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https://www.readbyqxmd.com/read/28628760/tuberculosis-incidence-among-people-living-with-hiv-aids-with-virological-failure-of-antiretroviral-therapy-in-salvador-bahia-brazil
#1
Monaliza Cardozo Rebouças, Márcio Oliveira da Silva, Tatiana Haguihara, Carlos Brites, Eduardo Martins Netto
Antiretroviral therapy (ART) for HIV has led to increased survival of HIV-infected patients. However, tuberculosis (TB) remains the leading opportunistic infection and cause of death among people living with HIV/AIDS (PLWHA). TB has been shown to be a good predictor of virological failure among PLWHA. This study aimed to evaluate the incidence of TB and its consequences among individuals diagnosed with virological failure of HIV. This was a retrospective cohort study involving PLWHA being followed-up in an AIDS reference center in Salvador, Bahia, Brazil...
June 16, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28564695/efficacy-and-tolerance-of-anti-tumor-necrosis-factor-%C3%AE-agents-in-cutaneous-sarcoidosis-a-french-study-of-46-cases
#2
Valentine Heidelberger, Saskia Ingen-Housz-Oro, Alicia Marquet, Matthieu Mahevas, Didier Bessis, Laurence Bouillet, Frédéric Caux, Catherine Chapelon-Abric, Sébastien Debarbieux, Emmanuel Delaporte, Anne-Bénédicte Duval-Modeste, Olivier Fain, Pascal Joly, Sylvain Marchand-Adam, Jean-Benoît Monfort, Nicolas Noël, Thierry Passeron, Marc Ruivard, Françoise Sarrot-Reynauld, Denis Verrot, Diane Bouvry, Laurence Fardet, Olivier Chosidow, Pascal Sève, Dominique Valeyre
Importance: Evidence for the long-term efficacy and safety of anti-tumor necrosis factor α agents (anti-TNF) in treating cutaneous sarcoidosis is lacking. Objective: To determine the efficacy and safety of anti-TNF in treating cutaneous sarcoidosis in a large observational study. Design, Setting, and Participants: STAT (Sarcoidosis Treated with Anti-TNF) is a French retrospective and prospective multicenter observational database that receives data from teaching hospitals and referral centers, as well as several pneumology, dermatology, and internal medicine departments...
May 31, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28533875/-management-of-spontaneous-pneumothorax-about-138-cases
#3
Bouchra Habibi, Leila Achachi, Sohaib Hayoun, Mohammed Raoufi, Laila Herrak, Mustapha El Ftouh
Pneumothorax is a collection of air in the pleural cavity. We conducted a retrospective study of patients with spontaneous pneumothorax in the Department of Pneumology at the Ibn Sina Hospital in Rabat (2009-2011) with the aim to determine the epidemiological, clinical, radiological, therapeutic and evolutionary manifestation of spontaneous pneumothorax. The study involved 138 patients: 128 men and 10 women (17-83 years), with an average age of 44.5 +/- 17.4 years and sex ratio of 12/8. 81.2% of patients were smokers...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28533690/accreditation-of-specialized-asthma-units-for-adults-in-spain-an-applicable-experience-for-the-management-of-difficult-to-control-asthma
#4
Carolina Cisneros, Rocío Magdalena Díaz-Campos, Núria Marina, Carlos Melero, Alicia Padilla, Silvia Pascual, Celia Pinedo, Andrea Trisán
This paper, developed by consensus of staff physicians of accredited asthma units for the management of severe asthma, presents information on the process and requirements for already-existing asthma units to achieve official accreditation by the Spanish Society of Pneumology and Thoracic Surgery (SEPAR). Three levels of specialized asthma care have been established based on available resources, which include specialized units for highly complex asthma, specialized asthma units, and basic asthma units. Regardless of the level of accreditation obtained, the distinction of "excellence" could be granted when more requirements in the areas of provision of care, technical and human resources, training in asthma, and teaching and research activities were met at each level...
2017: Journal of Asthma and Allergy
https://www.readbyqxmd.com/read/28504184/lessons-from-healthcare-utilization-in-children-with-obstructive-sleep-apnoea-syndrome
#5
Paz Martinez-Beneyto, Cristina E Soria Checa, Paloma Botella-Rocamora, Inés Rincon-Piedrahita, Francisco J Garcia Callejo, Jaime Marco Algarra
INTRODUCTION AND OBJECTIVES: Paediatric Obstructive Sleep Apnoea-Hypopnoea Syndrome (OSAS) is a multisystemic condition affecting child's health status that may be investigated analyzing demand for healthcare. OBJECTIVE: to quantify the frequency of medical consultations in children with OSAS over a 5-year period, compared to a healthy population. METHODS: A longitudinal, case-control, ambispective study was conducted at a hospital pertaining to the national public health system...
May 12, 2017: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/28484823/-prolonged-weaning-during-early-neurological-and-neurosurgical-rehabilitation-s2k-guideline-published-by-the-weaning-committee-of-the-german-neurorehabilitation-society-dgnr
#6
REVIEW
J D Rollnik, J Adolphsen, J Bauer, M Bertram, J Brocke, C Dohmen, E Donauer, M Hartwich, M D Heidler, V Huge, S Klarmann, S Lorenzl, M Lück, M Mertl-Rötzer, T Mokrusch, D A Nowak, T Platz, L Riechmann, F Schlachetzki, A von Helden, C W Wallesch, D Zergiebel, M Pohl
Prolonged weaning of patients with neurological or neurosurgery disorders is associated with specific characteristics, which are taken into account by the German Society for Neurorehabilitation (DGNR) in its own guideline. The current S2k guideline of the German Society for Pneumology and Respiratory Medicine is referred to explicitly with regard to definitions (e.g., weaning and weaning failure), weaning categories, pathophysiology of weaning failure, and general weaning strategies. In early neurological and neurosurgery rehabilitation, patients with central of respiratory regulation disturbances (e...
May 8, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/28431790/-barriers-to-referral-to-pulmonary-rehabilitation-in-copd-patients-from-the-perspective-of-general-practitioners
#7
O Galera, G Grimal, D Bajon, Y Darolles
INTRODUCTION: In spite of recommendations of the highest level of proof (rank A), the respiratory rehabilitation remains very widely sub-prescribed by general practitioners, who are nevertheless in the front line in the care and the follow-up of the patients affected by BPCO. MATERIAL AND METHODS: Semi-qualitative study with the general practitioners installed in the city of Montauban (Tarn-et-Garonne). RESULTS: The rate of answer was 57%...
April 18, 2017: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/28425888/-satisfa%C3%A3-%C3%A3-o-com-o-internato-m%C3%A3-dico-em-portugal
#8
Miguel Bigotte Vieira, Pedro Godinho, Nuno Gaibino, Raquel Dias, Agostinho Sousa, Inês Madanelo, Francisco Ribeiro-Mourão, Mariana Brandão, Sónia Duarte, Tiago Meirinhos, Ana Luísa Catarino, Cláudio Espírito Santo, Ricardo Caiado, Ricardo Marques, Ana Gonçalves Ferreira, Carlos Ramalheira, João Valente Jorge, Marta Losada, Mário Santos, Edson Oliveira, João Paulo Farias, José Manuel Silva
INTRODUCTION: In the last years, the global context of medical education and Medical Residency programs in Portugal suffered substantial changes. The primary objective of this study was to evaluate and characterize medical residents ́ satisfaction with medical residency programs in Portugal and to identify features that could be improved. MATERIAL AND METHODS: We utilized as model the survey Postgraduate Hospital Educational Environment Measure that has been developed in the United Kingdom and is speci cally targeted to medical residents...
December 30, 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28415992/women-epidemiology-lung-cancer-welca-study-reproductive-hormonal-occupational-risk-factors-and-biobank
#9
MULTICENTER STUDY
Isabelle Stücker, Diane Martin, Monica Neri, Pierre Laurent-Puig, Hélène Blons, Martine Antoine, Anne Guiochon-Mantel, Sylvie Brailly-Tabard, Marianne Canonico, Marie Wislez, Jean Trédaniel
BACKGROUND: Lung cancer aetiology and clinical aspects have been mainly studied in men, although specific risk factors probably exist in women. Here we present the rationale, design and organization of the WELCA study (Women Epidemiology Lung CAncer) that has been launched to investigate lung cancer in women, focusing particularly on hormonal and occupational factors. METHODS/DESIGN: WELCA is a population based case-control study and planned to recruit 1000 cases and 1000 controls in three years, based on study power calculation...
April 17, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28341462/asthma-management-in-a-specialist-setting-results-of-an-italian-respiratory-society-survey
#10
Fulvio Braido, Ilaria Baiardini, Pietro Alleri, Elena Bacci, Carlo Barbetta, Michela Bellocchia, Alida Benfante, Francesco Blasi, Caterina Bucca, Maria Teresa Busceti, Stefano Centanni, Maria Cristina Colanardi, Marco Contoli, Angelo Corsico, Maria D'Amato, Fabiano Di Marco, Dottorini Marco, Marta Ferrari, Giovanni Florio, Alessandro Giuseppe Fois, Maria Pia Foschino Barbaro, Garuti Silvia, Giuseppe Girbino, Amelia Grosso, Manuela Latorre, Sara Maniscalco, Francesco Mazza, Carlo Mereu, Giorgia Molinengo, Josuel Ora, Pierluigi Paggiaro, Vincenzo Patella, Girolamo Pelaia, Pietro Pirina, Alfio Proietto, Paola Rogliani, Pierachille Santus, Nicola Scichilone, Francesca Simioli, Paolo Solidoro, Silvia Terraneo, Umberto Zuccon, Giorgio Walter Canonica
BACKGROUND: Asthma considerably impairs patients' quality of life and increases healthcare costs. Severity, morbidity, and degree of disease control are the major drivers of its clinical and economic impact. National scientific societies are required to monitor the application of international guidelines and to adopt strategies to improve disease control and better allocate resources. AIM: to provide a detailed picture of the characteristics of asthma patients and modalities of asthma management by specialists in Italy and to develop recommendations for the daily management of asthma in a specialist setting...
June 2017: Pulmonary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28328094/asthma-management-a-new-phenotype-based-approach-using-presence-of-eosinophilia-and-allergy
#11
REVIEW
Milan Terl, Vratislav Sedlák, Petr Cap, Renata Dvořáková, Viktor Kašák, Tomáš Kočí, Bronislava Novotna, Ester Seberova, Petr Panzner, Vladimir Zindr
Asthma is a heterogeneous disease. The Czech Pneumology and Allergology Societies commissioned 10 experts to review the literature and create joint national guidelines for managing asthma, reflecting this heterogeneity. The aim was to develop an easy-to-use diagnostic strategy as a rational approach to the widening opportunities for the use of phenotype-targeted therapy. The guidelines were presented on websites for public comments by members of both the societies. The reviewers' comments contributed to creating the final version of the guidelines...
March 22, 2017: Allergy
https://www.readbyqxmd.com/read/28296367/-burden-of-hospitalization-for-pneumonia-in-a-spanish-tertiary-hospital-period-2009-2014
#12
Miguel López-Gobernado, Alberto Pérez-Rubio, Eva López-García, Agustín Mayo-Iscar, José María Eiros
BACKGROUND: The aim of this paper is to estimate the burden of hospitalization for community-acquired pneumonia and pneumococcal pneumonia at a tertiary level hospital in the Spanish National Health System. METHODS: A retrospective study which compiles data from the Minimum Data Set using clinical codes of the International Code of Diseases, as well as the hospitalization rate index per thousand inhabitants, the hospitalization rate per thousand population, mortality and fatality rate, using as denominator the demographic data of the population of the Health Area...
March 2017: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/28246498/a-case-control-study-of-risk-factors-associated-with-pulmonary-tuberculosis-in-romania-experience-at-a-clinical-hospital-of-pneumology
#13
Pacifique Ndishimye, Bianca Domokos, Jonathan Stillo, Fouad Seghrouchni, Oulaya Mrabet, Daniela Homorodean, Carmen Monica Pop, Abderrahim Sadak
BACKGROUND AND AIM: Tuberculosis (TB) remains a major public health issue in Romania. The aim of the present study was to evaluate the potential demographic, socioeconomic and behavioral risk factors for TB among hospitalized patients in Romania. METHODS: This is a case-control study conducted between March 1st 2014 and March 30th 2015 at Leon Daniello Clinical Hospital of Pneumology, Cluj Napoca. A total of 150 TB patients defined as "cases" were matched for age, sex and county of residence to 150 controls selected from patients attending the same hospital with respiratory diseases other than TB...
2017: Clujul Medical (1957)
https://www.readbyqxmd.com/read/28238515/factors-influencing-hospital-stay-for-pulmonary-embolism-a-cohort-study
#14
Nuria Rodríguez-Núñez, Alberto Ruano-Raviña, Romina Abelleira, Lucía Ferreiro, Adriana Lama, Francisco J González-Barcala, Antonio Golpe, María E Toubes, José M Álvarez-Dobaño, Luis Valdés
INTRODUCTION: The aim of this study was to identify factors influencing hospital stay due to pulmonary embolism. METHODS: We performed a retrospective cohort study of patients hospitalized between 2010 and 2015. Patients were identified using information recorded in hospital discharge reports (ICD-9-CM codes 415.11 and 415.19). RESULTS: We included 965 patients with a median stay of 8 days (IQR 6-13 days). Higher scores on the simplified Pulmonary Embolism Severity Index (sPESI) were associated with increased probability of longer hospital stay...
February 23, 2017: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/28222476/-positionpaper-on-telemonitoring-in-sleep-related-breathing-disorders
#15
W Randerath, M Bögel, C Franke, A Hellmann, B Jany, G Nilius, T Penzel, T Voshaar, A Wiater
The use of telemonitoring in the care of patients with Sleep-related Breathing Disorders (SBD) can enhance medical support significantly. Telemonitoring aims at helping physicians to detect therapy problems early and thus improve patients' therapy adherence. Diagnostics and therapy decisions in the telemonitoring process nevertheless remain the responsibility of sleep specialists. The selection of data monitored, their evaluation and resulting consequences fall to the physician, who makes decisions and prescribes therapy in consultation with the patient...
February 2017: Pneumologie
https://www.readbyqxmd.com/read/28212540/expression-of-met-in-circulating-tumor-cells-correlates-with-expression-in-tumor-tissue-from-advanced-stage-lung-cancer-patients
#16
Marius Ilie, Edith Szafer-Glusman, Véronique Hofman, Elodie Long-Mira, Rebecca Suttmann, Walter Darbonne, Catherine Butori, Salomé Lalvée, Julien Fayada, Eric Selva, Wei Yu, Charles-Hugo Marquette, David S Shames, Elizabeth Punnoose, Paul Hofman
Given the difficulty in obtaining adequate tissue in NSCLC, we investigated the utility of circulating tumor cells (CTCs) for MET status assessment in NSCLC patients. We used two platforms for CTC capture, and assessed MET expression in CTCs and matched-bronchial biopsies in patients with advanced-stage III/IV lung adenocarcinoma. Baseline peripheral blood was collected from 256 advanced-stage III/IV NSCLC patients from Genentech clinical trials, and from 106 patients with advanced-stage III/IV lung adenocarcinoma treated at the Department of Pneumology, Pasteur Hospital, Nice...
April 18, 2017: Oncotarget
https://www.readbyqxmd.com/read/28152018/acute-kidney-injury-burden-in-different-clinical-units-data-from-nationwide-survey-in-china
#17
Xiaojing Tang, Dongping Chen, Shengqiang Yu, Li Yang, Changlin Mei
BACKGROUND: The inpatient morbidity and mortality of acute kidney injury (AKI) vary considerably in different clinical units, yet studies to compare the difference remain limited. METHODS: We compared the clinical characteristics of AKI in Intensive Care Unit (ICU), medical and surgical departments by using the data derived from the 2013 nationwide cross-sectional survey of AKI in China to capture variations among different clinical departments in recognition, management, and outcomes of AKI...
2017: PloS One
https://www.readbyqxmd.com/read/28120698/short-course-daptomycin-lock-and-systemic-therapy-for-catheter-related-bloodstream-infections-a-retrospective-cohort-study-in-cancer-patients-with-surgically-implanted-devices
#18
Matteo Vassallo, Pierre-Luc Genillier, Brigitte Dunais, Regis Kaphan, Laurence Saudes, Yannick Duval, Fabien Rolland, Valerie Jullien, Nicolas Weiss, Elea Blanchouin, Annick Boscagli, Christophe Perrin, Nathalie Montagne
PURPOSE: Few in vivo studies have been reported describing efficacy and duration of antibiotic lock therapy (ALT) with daptomycin (DPT) for long-term catheter-related bloodstream infections (CRBSI) due to coagulase-negative staphylococci (CoNS). We retrospectively analysed the efficacy of short-course ALT with DPT in combination with systemic treatment (ST) for CoNS-associated CRBSI in our hospital. METHODS: Patients admitted for CoNS-associated CRBSI and treated with DPT as ALT and ST were retrospectively analysed...
January 25, 2017: Journal of Chemotherapy
https://www.readbyqxmd.com/read/28114706/-lung-health-data-of-the-study-of-health-in-pomerania-a-review-of-samples-methods-and-first-results
#19
R Ewert, T Ittermann, T Bollmann, T Spielhagen, M Dörr, C Schäper, C Warnke, A Obst, N Friedrich, S B Felix, M R P Markus, M Piontek, T Penzel, I Fietze, M Glos, B Stubbe, S Desole, S Kaczmarek, C O Schmidt, H Völzke, S Gläser
Investigating reasons for differing life expectancy and prevalence of cardiovascular risk factors between old and new states of the Federal Republic of Germany an epidemiological study in Western Pomerania - the population-based project Study of Health in Pomerania (SHIP) - was planned.Prevalence and incidence of common risk factors, subclinical disorders and clinical diseases have been assessed since 1997 in five-year intervals. The third follow up (SHIP-3) was assessed between 2014 and 2016. In addition, an independent representative population sample was investigated between 2008 - 2012 (SHIP-TREND)...
January 2017: Pneumologie
https://www.readbyqxmd.com/read/28051229/contribution-of-fixed-dose-combinations-in-the-treatment-of-tuberculosis
#20
Sonia Toujani, Boutheina Ben Safta, Nozha Ben Salah, Meriem Mjid, Yacine Ouahchi, Béchir Louzir, Jalloul Daghfous, Jouda Cherif, Nadia Mehiri, Majed Beji
Background - The introduction of fixed-dose combinations (FDCs) of TB treatment in Tunisia is recent (July 2009). WHO and the National Tuberculosis Programme recommend the use of fixed-dose combination (FDC) tablets for the treatment of tuberculosis (TB). The effectiveness of ADF has been demonstrated, however the risk of relapse and tolerance were controversial. Objective - Through a retrospective study, we evaluate, the contribution of FDCs compared with dissociated treatment (TD) (efficacy, tolerance and the occurrence of relapses)...
July 2016: La Tunisie Médicale
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