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https://www.readbyqxmd.com/read/28616897/alcohol-and-other-substance-use-among-a-sample-of-young-people-in-the-solomon-islands
#1
Brendan Quinn, Elizabeth Peach, Cassandra J C Wright, Megan S C Lim, Lisa Davidson, Paul Dietze
OBJECTIVE: Investigate alcohol and other substance use, with a focus on harmful alcohol use patterns, among young people in the Solomon Islands. METHODS: A structured, interviewer-administered questionnaire was administered to respondents aged 15-24 years across four of the country's provinces in late 2015. RESULTS: Four hundred young people completed the questionnaire across urban, peri-urban and rural communities. The most common substances ever used by participants were betel nut (94%), licit/store-bought and/or illicit alcohol (79%) and tobacco (76%)...
June 14, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/28608829/providing-a-clean-environment-for-adolescents-evaluation-of-the-tobacco-hazards-prevention-act-in-taiwan
#2
Min-Li Chen, Li-Na Chou, Ya-Cheng Zheng
Cigarette smoking not only damages the health of adolescents, but also contributes to air pollution. The Tobacco Hazards Prevention Act in Taiwan stipulates that cigarettes should not be sold to persons younger than 18 years. Therefore, schools should actively educate students and raise awareness of the Tobacco Hazards Prevention Act to reduce the level of damage to the health of adolescents and maintain good air quality. This study had two main goals: (1) to evaluate the stipulation that no person shall provide tobacco products to persons under the age of 18 and the effects of counseling strategies on store managers confirming customer ages before tobacco sale in southern Taiwan; and (2) to evaluate the situation of tobacco hazard prevention education conducted by school in southern Taiwan...
June 13, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28607245/opportunities-in-oral-health-policy-for-timor-leste
#3
Lucio F Babo Soares, Silvana S Bettiol, Isaac J Dalla-Fontana, Penny Allen, Leonard A Crocombe
Timor-Leste faces an urgent set of challenges in oral health. The impact of oral diseases in terms of reduced quality of life and cost of treatment is considerable. This paper reviews progress on policy recommendations since the National Oral Health Survey in 2002, the first such national survey. Few proposals have been implemented to date, owing to (i) lack of local support for the recommendations, particularly on promotion of oral health; (ii) lack of financial and budgetary provisions for oral health; (iii) lack of focus on services, human resources and dental personnel; (iv) poor focus, design and implementation of policy and planning in oral health; and (v) lack of transport to facilitate health-care workers' access to remote areas...
September 2016: WHO South-East Asia Journal of Public Health
https://www.readbyqxmd.com/read/28580560/-a-symbol-of-connectedness-between-the-self-and-the-tribal-home-betel-quid-in-the-lives-of-indigenous-taiwanese
#4
Wei-Fen Ma, Chia-Ing Li, Ellen R Gritz, Irene Tamí-Maury, Cho Lam, Cheng-Chieh Lin
BACKGROUND: Betel quid chewing plays a significant role in the development of oral cancer, yet the high prevalence of betel quid use remains a serious health problem in Taiwan, especially among indigenous Taiwanese. PURPOSE: The present study aimed to understand the reasons behind betel-quid chewing among indigenous Taiwanese people by examining the larger context of their culture and traditions. METHODS: This descriptive, qualitative study recruited ten regular betel quid indigenous chewers using purposive and snowball sampling...
June 2017: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/28573260/trend-analysis-of-betel-nut-associated-oral-cancer-%C3%A2-and-health-burden-in-china
#5
Yan Jia Hu, Jie Chen, Wai Sheng Zhong, Tian You Ling, Xin Chun Jian, Ruo Huang Lu, Zhan Gui Tang, Lin Tao
OBJECTIVE: To forecast the future trend of betel nut-associated oral cancer and the resulting burden on health based on historical oral cancer patient data in Hunan province, China. METHODS: Oral cancer patient data in five hospitals in Changsha (the capital city of Hunan province) were collected for the past 12 years. Three methods were used to analyse the data; Microsoft Excel Forecast Sheet, Excel Trendline, and the Logistic growth model. A combination of these three methods was used to forecast the future trend of betel nut-associated oral cancer and the resulting burden on health...
2017: Chinese Journal of Dental Research
https://www.readbyqxmd.com/read/28573078/petroleum-carcinogenicity-and-aerodigestive-tract-in-context-of-developing-nations
#6
REVIEW
Sunali Khanna, Amit S Gharpure
Head and neck cancers from a diverse group of neoplasms, the occurrence of which can be attributed to habitual tobacco use, race, alcohol consumption, ultraviolet (UV) exposure, occupational exposure, viruses, and diet. The surging incidence rates reflect the prevalence of risk factors such as tobacco use (smoked and smokeless), betel nut chewing, urbanization and issues relating to urban air quality. Urbanization and development have catalyzed a multifold rise in levels of pollution in metropolitan cities...
April 30, 2017: Curēus
https://www.readbyqxmd.com/read/28473740/adult-mortality-of-diseases-and-injuries-attributable-to-selected-metabolic-lifestyle-environmental-and-infectious-risk-factors-in-taiwan-a-comparative-risk-assessment
#7
Wei-Cheng Lo, Chu-Chang Ku, Shu-Ti Chiou, Chang-Chuan Chan, Chi-Ling Chen, Mei-Shu Lai, Hsien-Ho Lin
BACKGROUND: To facilitate priority-setting in health policymaking, we compiled the best available information to estimate the adult mortality (>30 years) burden attributable to 13 metabolic, lifestyle, infectious, and environmental risk factors in Taiwan. METHODS: We obtained data on risk factor exposure from nationally representative health surveys, cause-specific mortality from the National Death Registry, and relative risks from epidemiological studies and meta-analyses...
2017: Population Health Metrics
https://www.readbyqxmd.com/read/28468625/adult-mortality-of-diseases-and-injuries-attributable-to-selected-metabolic-lifestyle-environmental-and-infectious-risk-factors-in-taiwan-a-comparative-risk-assessment
#8
Wei-Cheng Lo, Chu-Chang Ku, Shu-Ti Chiou, Chang-Chuan Chan, Chi-Ling Chen, Mei-Shu Lai, Hsien-Ho Lin
BACKGROUND: To facilitate priority-setting in health policymaking, we compiled the best available information to estimate the adult mortality (>30 years) burden attributable to 13 metabolic, lifestyle, infectious, and environmental risk factors in Taiwan. METHODS: We obtained data on risk factor exposure from nationally representative health surveys, cause-specific mortality from the National Death Registry, and relative risks from epidemiological studies and meta-analyses...
May 3, 2017: Population Health Metrics
https://www.readbyqxmd.com/read/28468586/alteration-in-the-expression-of-mgmt-and-runx3-due-to-non-cpg-promoter-methylation-and-their-correlation-with-different-risk-factors-in-esophageal-cancer-patients
#9
Snigdha Saikia, Asad Ur Rehman, Prajjalendra Barooah, Preeti Sarmah, Mallika Bhattacharyya, Muktanjalee Deka, Manab Deka, Bhabadev Goswami, Syed Akhtar Husain, Subhash Medhi
Promoter methylation reflects in the inactivation of different genes like O(6)-methylguanine-DNA methyltransferase DNA repair gene and runt-related transcription factor 3, a known tumor suppressor gene in various cancers such as esophageal cancer. The promoter methylation was evaluated for O(6)-methylguanine-DNA methyltransferase and runt-related transcription factor 3 in CpG, CHH, and CHG context (where H is A, T, or C) by next-generation sequencing. The methylation status was correlated with quantitative messenger RNA expression...
May 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28426731/effect-of-genetic-variation-in-microrna-binding-site-in-wnt1-inducible-signaling-pathway-protein-1-gene-on-oral-squamous-cell-carcinoma-susceptibility
#10
Hon-Kit Lau, Edie-Rosmin Wu, Mu-Kuan Chen, Ming-Ju Hsieh, Shun-Fa Yang, Lyu-Yao Wang, Ying-Erh Chou
BACKGROUND: Oral squamous cell carcinoma (OSCC), which is the most common head and neck cancer, accounts for 1%-2% of all human malignancies and is characterized by poor prognosis and reduced survival rates. WNT1-inducible signaling pathway protein 1 (WISP1), a cysteine-rich protein belonging to the Cyr61, CTGF, Nov (CCN) family of matricellular proteins, has many developmental functions and may be involved in carcinogenesis. This study investigated WISP1 single-nucleotide polymorphisms (SNPs) to elucidate OSCC susceptibility and clinicopathologic characteristics...
2017: PloS One
https://www.readbyqxmd.com/read/28404909/impact-of-ccl4-gene-polymorphisms-and-environmental-factors-on-oral-cancer-development-and-clinical-characteristics
#11
Ming-Yu Lien, Chiao-Wen Lin, Hsiao-Chi Tsai, Yng-Tay Chen, Ming-Hsui Tsai, Chun-Hung Hua, Shun-Fa Yang, Chih-Hsin Tang
In Taiwan, oral cancer has causally been associated with environmental carcinogens. CCL4 (C-C chemokine ligand 4), a macrophage inflammatory protein with a key role in inflammation and immune-regulation, was implicated in carcinogenesis by facilitating instability in the tumor environment. The purpose of this study was to identify gene polymorphisms of CCL4 specific to patients with oral squamous cell carcinoma (OSCC) susceptibility and clinicopathological characteristics. A total of 2,053 participants, including 1192 healthy people and 861 patients with oral cancer, were recruited for this study...
May 9, 2017: Oncotarget
https://www.readbyqxmd.com/read/28383824/implication-for-second-primary-cancer-from-visible-oral-and-oropharyngeal-premalignant-lesions-in-betel-nut-chewing-related-oral-cancer
#12
Shyun-Yu Liu, I-Jung Feng, Yu-Wei Wu, Ching-Yuan Chen, Chao-Nan Hsiung, Hsueh-Wei Chang, Che-Yi Lin, Min-Te Chang, Hsi-Chien Yu, Sheng-Yang Lee, Ching-Yu Yen
BACKGROUND: Visible oral and oropharyngeal premalignant lesions may be used to monitor for a second primary oral cancer. To control for bias, we focused on the visible oral and oropharyngeal premalignant lesions of patients with oral cancer with a positive betel-nut chewing habit. Visible oral and oropharyngeal premalignant lesions that can predict second primary oral cancers were studied. METHODS: Nine hundred ninety-seven patients with positive betel-nut chewing habits and oral cancer were enrolled in this retrospective cohort study...
April 6, 2017: Head & Neck
https://www.readbyqxmd.com/read/28317358/-epidemiological-investigation-of-chewing-fresh-or-dried-betel-nut-and-oral-mucosal-disease
#13
Du Yongxiu, Sun Dongye, Jian Xinchun, Mao Qiuhua, Cheng Yanan, Xu Pu
OBJECTIVE: This study was conducted to investigate the effect of chewing fresh or dried betel nut on the inci-dence and canceration of oral mucosa disease in Haikou City in Hainan Province. METHODS: Through a survey questionnaire, clinical examination, and regular follow-up, we collected clinical data from 1 722 cases and divided them into two groups, among which 704 of the afflicted people chew dried betel nut, whereas the other 1 018 chew fresh betel nut. The data were 
statistically analyzed using different variables which included age, number, time of onset of the disease, and the cancerous condition associated with common oral mucosa disease, including oral submucous fibrosis (OSF), oral leukoplakia (OLK), and oral Lichen planus (OLP)...
August 1, 2016: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28278615/in-vitro-cholinesterase-inhibitory-activity-of-some-plants-used-in-iranian-traditional-medicine
#14
Mina Saeedi, Khatereh Babaie, Elahe Karimpour-Razkenari, Mahdi Vazirian, Tahmineh Akbarzadeh, Mahnaz Khanavi, Mannan Hajimahmoodi, Mohammad Reza Shams Ardekani
In this study, in vitro evaluation of cholinesterase inhibitory (ChEI) activity of various plants including betel nuts (Areca catechu L.), clove buds (Syzygium aromaticum L.), aerial parts of dodder (Cuscuta chinensis Lam.), common polypody rhizomes (Polypodium vulgare L.) and turpeth roots (Ipomoea turpethum R. Br.) which were recommended for the treatment of AD symptoms in Iranian Traditional Medicine (ITM) is reported. Among them, aqueous extract of A. catechu L. was found as the most potent anti-AChE (IC50 = 32...
March 6, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28277392/impaired-kidney-function-and-associated-factors-among-rural-adults-with-disabilities-in-taiwan
#15
Chu-Yeh Chen, Wen-Nan Chiu, Yu-Chen Lin, Sui-Hwi Jane, Hsin-Hung Chiang, Mei-Yen Chen
BACKGROUND: The results of numerous studies indicate that people with disabilities seek more healthcare than those who are not disabled, particularly for conditions such as chronic kidney disease, cardiovascular disease, and obesity. However, little is known about the incidence of impaired kidney function and its associated factors among adults with disabilities in Taiwan. PURPOSE: The aim of this study was to explore the prevalence and factors associated with impaired kidney function among adults with disabilities...
April 2017: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/28272042/utilization-of-two-agrowastes-for-adsorption-and-removal-of-methylene-blue-kinetics-and-isotherm-studies
#16
Manash Deep Dey, Minhaz Ahmed, Ranjana Singh, Ratan Boruah, Rupak Mukhopadhyay
Fresh water streams contaminated with synthetic dye-containing effluents pose a threat to aquatic and human life either by preventing aquatic photosynthesis or by entering into the food chain. Adsorptive removal of such dyes with potent biosorbents is an important technique to reduce bioaccumulation and biomagnifications of the dyes in human life. We report use of betel nut (BN) husk and banana peel (BP), two most abundant ligno-cellulosic wastes, as efficient adsorbents for the removal of the basic dye methylene blue (MB)...
March 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28265049/the-ethics-of-betel-nut-consumption-in-taiwan
#17
Joseph Tham, Geoffrey Sem, Eugene Sit, Michael Cheng-Tek Tai
The ethics of betel nut use in Taiwan are examined in this article. It first presents scientific facts about the betel quid, its consumption and negative health consequences and then analyses the cultural background and economic factors contributing to its popularity in Asia. Governmental and institutional attempts to curb betel nut cultivation, distribution and sales are also described. Finally, the bioethical implications of this often ignored subject are considered.
March 6, 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/28230921/prevalence-of-promoter-mutations-in-the-tert-gene-in-oral-cavity-squamous-cell-carcinoma
#18
Kai-Ping Chang, Chun-I Wang, Curtis R Pickering, Yenlin Huang, Chi-Neu Tsai, Ngan-Ming Tsang, Huang-Kai Kao, Ming-Huei Cheng, Jeffrey N Myers
BACKGROUND: Mutations in the human telomerase reverse transcriptase (TERT) promoter contribute to increased TERT activity. The purpose of the present study was to assess the prevalence of TERT promoter mutations in oral cavity squamous cell carcinoma (SCC). METHODS: Total DNA was extracted from 201 oral cavity SCC tumors and adjacent normal tissues. Primers were used to amplify the sequence region containing 2 TERT promoter mutations (C228T and C250T) that were then sequenced using the Sanger method...
February 23, 2017: Head & Neck
https://www.readbyqxmd.com/read/28225785/betel-nut-chewing-oral-premalignant-lesions-and-the-oral-microbiome
#19
Brenda Y Hernandez, Xuemei Zhu, Marc T Goodman, Robert Gatewood, Paul Mendiola, Katrina Quinata, Yvette C Paulino
Oral cancers are attributed to a number of causal agents including tobacco, alcohol, human papillomavirus (HPV), and areca (betel) nut. Although betel nut chewing has been established as an independent cause of oral cancer, the mechanisms of carcinogenesis are poorly understood. An investigation was undertaken to evaluate the influence of betel nut chewing on the oral microbiome and oral premalignant lesions. Study participants were recruited from a dental clinic in Guam. Structured interviews and oral examinations were performed...
2017: PloS One
https://www.readbyqxmd.com/read/28219593/betel-nut-chewing-is-associated-with-reduced-tacrolimus-concentration-in-taiwanese-liver-transplant-recipients
#20
COMPARATIVE STUDY
W-Y Chen, C-Y Lee, P-Y Lin, C-E Hsieh, C-J Ko, K-H Lin, C-C Lin, Y-Z Ming, Y-L Chen
PURPOSE: Studies have shown that arecoline, the major alkaloid component of betel nuts, alters the activity of enzymes in the cytochrome P450 (CYP-450) family. Tacrolimus, an immunosuppressant that protects against organ rejection in transplant recipients, not only is mainly metabolized by CYP3A enzymes but also has a narrow therapeutic range. We aimed to investigate whether dose-adjusted blood trough levels of tacrolimus differed over time between betel nut-chewing and non-betel nut-chewing liver transplant recipients...
March 2017: Transplantation Proceedings
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