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"Betel nut"

Palak Hasmukhbhai Shah, Rashmi Venkatesh, Chandramani Bhagawan More, Vaishnavee Vassandacoumara
INTRODUCTION: Oral Submucous Fibrosis (OSMF) is a potentially malignant disease of the oral cavity associated with betel nut chewing. The management of OSMF has been a subject of controversy and no definitive and widely accepted treatment is currently available for this condition. AIM: To retrospectively evaluate the therapeutic efficacy of two treatment regimens (placental extract with dexamethasone and hyaluronic acid with dexamethasone) for the treatment of OSMF...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
Chuan-Yi Lin, Yi-Ho Young
OBJECTIVE: This study investigated the effect of betel nut chewing on the otolithic reflex system. METHODS: Seventeen healthy volunteers without any experience of chewing betel nut (fresh chewers) and 17 habitual chewers underwent vital sign measurements, ocular vestibular-evoked myogenic potential (oVEMP), and cervical VEMP (cVEMP) tests prior to the study. Each subject then chewed two pieces of betel nut for 2min (dosing). The same paradigm was repeated immediately, 10min, and 20min after chewing...
October 13, 2016: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
Manjiri Joshi, Mansi Tailor
BACKGROUND: Oral cancer is a major health problem in tobacco users worldwide and is one of the ten most common cancers. India alone accounts for 1/3 rd of the world's oral cancer and has a high rate of potentially malignant disorders (PMDs). The most common predisposing factors are smoking, smokeless tobacco, betel nut in quid form (pan), alcohol, spicy food, and sharp broken tooth. There are various tobacco-associated lesions (TALs) which can be diagnosed at very early stage. This study was conducted to rule out association of smoking and smokeless tobacco with occurrence of TALs and its dose-response relationship...
July 2016: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
Chien-Pang Lee, Yen-Hsin Lee, Ie-Bin Lian, Che-Chun Su
Background: Heavy metal pollution in farm soils is a grave concern in Taiwan. Previously, we found the incidence of oral cancer (OC) correlated positively with levels of nickel and arsenic in farm soils. Many OC patients have a second malignancy, among which esophageal cancer (EC) is the most common one in Taiwan. Objectives: We aimed to investigate whether these two cancers share some common risk factors. Methods: Taiwan began a compulsory national health insurance program in 1995. We used a database from this program to calculate the prevalence of EC and OC in Taiwan...
2016: Journal of Cancer
Tsui-Yun Yang, Hung-Ru Lin
AIM AND OBJECTIVES: To understand taxi drivers' successful experiences of quitting betel nut chewing. BACKGROUND: Previous studies verified that betel nut chewing significantly increases the risk of oral cancer. In Taiwan, taxi drivers work for approximately 10-13 hours per day, and 31.7-80% of them choose to chew betel nuts for their invigorating qualities, which enable them to work more hours and receive more income. DESIGN: A qualitative research design was used...
September 29, 2016: Journal of Clinical Nursing
Darrin V Bann, Daniel G Deschler, Neerav Goyal
The immune system plays a key role in preventing tumor formation by recognizing and destroying malignant cells. For over a century, researchers have attempted to harness the immune response as a cancer treatment, although this approach has only recently achieved clinical success. Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide and is associated with cigarette smoking, alcohol consumption, betel nut use, and human papillomavirus infection. Unfortunately, worldwide mortality from HNSCC remains high, partially due to limits on therapy secondary to the significant morbidity associated with current treatments...
September 22, 2016: Cancers
Narongrit Juntanong, Pallop Siewchaisakul, Peter Bradshaw, Patravoot Vatanasapt, Sam Li-Sheng Chen, Amy Ming-Fang Yen, Tony Hsiu-Hsi Chen, Supannee Promthet
BACKGROUND: Oral cavity cancer (OCC) is one of the most common cancers worldwide. No studies have reported on the prevalence and epidemiologic risk factors of oral premalignant lesions (OPLs) in Thailand. The purpose of this study was to investigate the prevalence of OPLs and associated factors in Roi Et Province, Thailand. MATERIALS AND METHODS: To investigate the prevalence of OPLs, a cross-sectional descriptive study was conducted in which 2,300 subjects over 40 years of age were recruited and screened for the prevalence of OPLs...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
Kshama Nimkar, Dinesh Sood, Pawan Soni, Narvir Chauhan, Mukesh Surya
BACKGROUND: We present unique case of a giant extracranial atretic occipital lipoencephalocele in an adult patient with new bone formation within it which was not associated with any developmental malformation of brain. Resection of the lipoencephalocele was performed for esthetic reasons. CASE REPORT: 18 year old female patient presented to the surgery OPD with complains of a large mass in the occipital region present since birth. It was of size of a betel nut at the time of birth and gradually increased in size over a long period of time...
2016: Polish Journal of Radiology
I-Hsuan Su, Chen-Fu Lee, Yu-Pin Su, Lai-Hao Wang
OBJECTIVES: To study using cobalt-tetraphenylporphyrin/reduced graphene oxide (CoTPP/RGO), a nanocomposite highly catalytic both for oxidizing and for reducing hydrogen peroxide (H2 O2 ), to whiten teeth. METHODS: Dyes (D&C Red 34, Orange No. 4), tea, and betel nuts (Areca catechu) were used to stain the tooth specimens for three days and subsequently bleached using H2 O2 alone, H2 O2 plus CoTPP, or H2 O2 plus CoTPP/RGO for 0.5-70 hours. The process was photographed using an electronic chromometer and a camera...
September 2016: Journal of Esthetic and Restorative Dentistry
Shih-Chi Su, Ming-Ju Hsieh, Yu-Fan Liu, Ying-Erh Chou, Chiao-Wen Lin, Shun-Fa Yang
BACKGROUND: Oral cancer is a common malignancy that is shown to be causally associated with hereditary and acquired factors. ADAMTS14 is a member of the ADAMTS (a disintegrin-like and metalloproteinase domain with thrombospondin motifs) metalloproteinase family that plays an important role in extracellular matrix (ECM) assembly and degradation. Elevation or deficiency of certain ADAMTS proteinases has been known to be implicated in a wide range of pathological processes including atherosclerosis, arthritis, and cancer...
2016: PloS One
Pai-Tai Tsai, Yi-Shing Shieh, Chi-Tsung Wu, Shiao-Pieng Lee, Yuan-Wu Chen
PURPOSE: Little is known about whether buccal mucosa elasticity influences the determination of surgical margins for buccal carcinomas. This study investigated whether there is a difference in elasticity of the buccal mucosa in patients with buccal carcinoma compared with controls without the disease. PATIENTS AND METHODS: A case-and-control study comprised of patients with buccal carcinoma and controls without the disease was conducted. In each patient, 2 gutta-percha points were attached to the buccal mucosa horizontally and examined twice by lateral cephalometry, once with the mouth closed and once during maximal mouth opening (MMO)...
September 2016: Journal of Oral and Maxillofacial Surgery
Szu-Yuan Wu, Alexander T H Wu, Shing-Hwa Liu
Betel nut chewing is associated with oral cavity cancer. Radiotherapy is one of the therapeutic approaches. Here, we used miR-17-5p antisense oligonucleotides (AS-ODNs) and human apoptosis protein array to clarify which apoptosis-related proteins are increased or decreased by miR-17-5p in betel nut chewing- oral squamous cell carcinoma OC3 cells. Furthermore, miR-17-5p AS-ODN was used to evaluate the radio-sensitization effects both in vitro and in vivo. An OC3 xenograft tumor model in severe combined immunodeficiency mice was used to determine the effect of miR-17-5p AS ODN on tumor irradiation...
June 6, 2016: Oncotarget
R Merchant, J E Gallagher, S E Scott
OBJECTIVES: First, to evaluate awareness of oral cancer amongst the young South-Asian community in London and identify any aspects of knowledge about oral cancer that are lacking; and, second, to determine whether demographic factors or health-related behaviours are associated with knowledge of oral cancer. RESEARCH DESIGN: Cross-sectional questionnaire survey. PARTICIPANTS: South Asians aged 18-44 years attending community centres or places of worship in London...
March 2016: Community Dental Health
Wen-Lun Wang, I-Wei Chang, Chien-Chuan Chen, Chi-Yang Chang, Jaw-Town Lin, Lein-Ray Mo, Hsiu-Po Wang, Ching-Tai Lee
Early esophageal squamous cell neoplasias (ESCNs) are easily missed with conventional white-light endoscopy. This study aimed to assess whether early ESCNs have a spatial predilection and the patterns of recurrence after endoscopic treatment. We analyzed the circumferential and longitudinal location of early ESCNs, as well as their correlations with exposure to carcinogens in a cohort of 162 subjects with 248 early ESCNs; 219 of which were identified by screening and 29 by surveillance endoscopy. The circumferential location was identified using a clock-face orientation, and the longitudinal location was identified according to the distance from the incisor...
April 2016: Medicine (Baltimore)
Sindy Hu, Wen-Chyuan Chen, Guey-Shyang Hwang, Szu-Tah Chen, Song-Bor Kuo, Yifen Chen, Galina Idova, Shyi-Wu Wang
Betel nut is the second largest economic food product in Taiwan. In Southeast Asia, the habit of chewing betel nut seems to be highly correlated with oral submucous fibrosis and oral squamous cell carcinoma. Oral submucous fibrosis is characterized by abnormal accumulation of oral submucous collagen fibers and limitation of mouth opening. Although the mechanism responsible for tissue damage is still unknown, prolonged irritation caused by betel nut and tobacco is considered to be a major factor contributing to the pathogenesis of oral submucous fibrosis...
July 2016: Steroids
Yan-Ye Su, Chih-Yen Chien, Sheng-Dean Luo, Tai-Lin Huang, Wei-Che Lin, Fu-Min Fang, Tai-Jan Chiu, Yen-Hao Chen, Chi-Chih Lai, Cheng-Ming Hsu, Shau-Hsuan Li
BACKGROUND: Smoking and betel nut chewing are well-known risk factors for head and neck squamous cell carcinoma (HNSCC). Smoking is also a strong prognosticator for patients with locally advanced HNSCC receiving induction chemotherapy. Smoking with or without betel nut chewing is a common practice in Asia. However, little is known regarding whether betel nut chewing can serve as a prognostic factor for smoking patients with locally advanced HNSCC receiving induction chemotherapy. The aim of this study was to evaluate the prognostic impact of betel nut chewing in such patients receiving induction chemotherapy with docetaxel, cisplatin, and fluorouracil (TPF)...
2016: World Journal of Surgical Oncology
Chu-Yeh Chen, Wen-Nan Chiu, Yu-Chen Lin, Sui-Hwi Jane, Hsin-Hung Chiang, Mei-Yen Chen
BACKGROUND: The results of numerous studies indicate that people with disabilities seek more healthcare than those who are not disabled, particularly for conditions such as chronic kidney disease, cardiovascular disease, and obesity. However, little is known about the incidence of impaired kidney function and its associated factors among adults with disabilities in Taiwan. PURPOSE: The aim of this study was to explore the prevalence and factors associated with impaired kidney function among adults with disabilities...
March 19, 2016: Journal of Nursing Research: JNR
Katherine E Berger, James Masterson, Joy Mascardo, Jayvee Grapa, Inger Appanaitis, Everlynn Temengil, Berry Moon Watson, Haley L Cash
The small Pacific Island nation of Palau has alarmingly high rates of betel nut with tobacco use and obesity among the entire population including pregnant women. This study aimed to determine the effects of betel nut with tobacco use and pre-pregnancy obesity on adverse birth outcomes. This study used retrospective cohort data on 1171 Palauan women who gave birth in Belau National Hospital in Meyuns, Republic of Palau between 2007 and 2013. The exposures of interest were pre-pregnancy obesity and reported betel nut with tobacco use during pregnancy...
August 2016: Maternal and Child Health Journal
Jessica Nishikawa
No abstract text is available yet for this article.
October 20, 2016: Nurse Practitioner
S Preethi, Joy Idiculla Jose, B Sivapathasundharam, B Sabarinath
INTRODUCTION: Nitric oxide (NO), a free radical, acts as a signalling molecule affecting numerous physiological and pathological processes. Role of nitric oxide as a mediator in tobacco related habits and the resultant oral lichenoid reactions was assessed. AIM: The aim of the study is to evaluate and compare the salivary nitric oxide levels in normal patients with that of smokers, tobacco chewers and patients with oral lichenoid reactions. MATERIALS AND METHODS: One hundred and twenty patients were enrolled in the study which included 30 healthy patients without any chronic inflammatory lesion and habit as controls (group I), 30 smokers without the habit of tobacco/betel nut chewing and any oral lesion (group II), 30 tobacco chewers without the habit of smoking and any oral lesion (group III) and 30 histologically confirmed cases of oral lichenoid reaction with the habit of tobacco usage (group IV)...
January 2016: Journal of Clinical and Diagnostic Research: JCDR
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