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https://www.readbyqxmd.com/read/27906505/what-do-we-learn-about-development-from-baby-robots
#1
Pierre-Yves Oudeyer
Understanding infant development is one of the great scientific challenges of contemporary science. In addressing this challenge, robots have proven useful as they allow experimenters to model the developing brain and body and understand the processes by which new patterns emerge in sensorimotor, cognitive, and social domains. Robotics also complements traditional experimental methods in psychology and neuroscience, where only a few variables can be studied at the same time. Moreover, work with robots has enabled researchers to systematically explore the role of the body in shaping the development of skill...
December 1, 2016: Wiley Interdisciplinary Reviews. Cognitive Science
https://www.readbyqxmd.com/read/27906467/-nursing-research-culture-in-the-context-of-clinical-nursing-practice-addressing-a-conceptual-problem
#2
Connie Bøttcher Berthelsen, Bibi Hølge-Hazelton
AIM: To report an analysis of the concept of nursing research culture in the context of clinical nursing practice. BACKGROUND: Nursing research culture should be valued for its contribution to improving patient care and should be considered as a routine hospital activity. However, the demand for efficiency, nurses' barriers to research use and the lack of definition of the concept of nursing research culture make it difficult to establish. DESIGN: Concept analysis...
December 1, 2016: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/27906461/measurement-of-intestinal-and-peripheral-cholesterol-fluxes-by-a-dual-tracer-balance-method
#3
Onne A H O Ronda, Theo H van Dijk, H J Verkade, Albert K Groen
Long-term elevated plasma cholesterol levels put individuals at risk for developing atherosclerosis. Plasma cholesterol levels are determined by the balance between cholesterol input and output fluxes. Here we describe in detail the methodology to determine the different cholesterol fluxes in mice. The percentage of absorbed cholesterol is calculated from a stable isotope-based double-label method. Cholesterol synthesis is calculated from MIDA after (13) C-acetate enrichment. Cholesterol is removed from the body via the feces...
December 1, 2016: Current Protocols in Mouse Biology
https://www.readbyqxmd.com/read/27906447/validation-of-the-parental-facilitation-of-mastery-scale-ii
#4
Alyson K Zalta, Kelly M Allred, Eranda Jayawickreme, Laura E R Blackie, Dianne L Chambless
To develop a more reliable and comprehensive version of the Parental Facilitation of Mastery Scale (PFMS) METHOD: In Study 1, 387 undergraduates completed an expanded PFMS (PFMS-II) and measures of parenting, perceived control, responses to early life challenges, and psychopathology. In Study 2, 182 trauma-exposed community participants completed the PFMS-II and measures of perceived control, psychopathology, and well-being RESULTS: In Study 1, exploratory factor analysis of the PFMS-II revealed two factors...
December 1, 2016: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/27906394/formal-nucleophilic-borylation-and-borylative-cyclization-of-organic-halides
#5
REVIEW
K Kubota, H Iwamoto, H Ito
This review describes recent advances in direct borylation reactions of organic halides, including both transition-metal-catalyzed and metal-free methods. Since the pioneering work on palladium-catalyzed boryl substitution of aryl halides with a diboron compound reported by Miyaura and co-workers in 1995, various catalytic systems for the borylation of aryl, alkneyl, and alkyl halides have been developed to give a wide range of organoboronate esters that cannot be synthesized using conventional methods. Borylative cyclization of alkyl halides is also discussed...
December 1, 2016: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/27906387/hierarchically-porous-materials-synthesis-strategies-and-structure-design
#6
REVIEW
Xiao-Yu Yang, Li-Hua Chen, Yu Li, Joanna Claire Rooke, Clément Sanchez, Bao-Lian Su
Owing to their immense potential in energy conversion and storage, catalysis, photocatalysis, adsorption, separation and life science applications, significant interest has been devoted to the design and synthesis of hierarchically porous materials. The hierarchy of materials on porosity, structural, morphological, and component levels is key for high performance in all kinds of applications. Synthesis and applications of hierarchically structured porous materials have become a rapidly evolving field of current interest...
December 1, 2016: Chemical Society Reviews
https://www.readbyqxmd.com/read/27906339/shaping-of-ultraviolet-femtosecond-laser-pulses-by-fourier-domain-harmonic-generation
#7
E Hertz, F Billard, G Karras, P Béjot, B Lavorel, O Faucher
We present a method to finely tailor ultraviolet femtosecond laser pulses using a pulse shaper with ability in the infrared/visible spectral range. We have developed to that end a frequency doubling module in which the up-conversion mechanism is carried out in the Fourier plane of a 4 f -line. The pulse shaper is used to imprint a spectral phase and/or amplitude onto the fundamental pulse. The shaped pulse is then frequency doubled through the module which transfers the applied spectral shaping to the second harmonic field in a predictable manner...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27906334/hyperspectral-face-recognition-using-improved-inter-channel-alignment-based-on-qualitative-prediction-models
#8
Woon Cho, Jinbeum Jang, Andreas Koschan, Mongi A Abidi, Joonki Paik
A fundamental limitation of hyperspectral imaging is the inter-band misalignment correlated with subject motion during data acquisition. One way of resolving this problem is to assess the alignment quality of hyperspectral image cubes derived from the state-of-the-art alignment methods. In this paper, we present an automatic selection framework for the optimal alignment method to improve the performance of face recognition. Specifically, we develop two qualitative prediction models based on: 1) a principal curvature map for evaluating the similarity index between sequential target bands and a reference band in the hyperspectral image cube as a full-reference metric; and 2) the cumulative probability of target colors in the HSV color space for evaluating the alignment index of a single sRGB image rendered using all of the bands of the hyperspectral image cube as a no-reference metric...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27906296/numerical-modeling-of-fiber-specklegram-sensors-by-using-finite-element-method-fem
#9
V H Arístizabal, F J Vélez, E Rueda, N D Gómez, J A Gómez
Although experimental advances in the implementation and characterization of fiber speckle sensor have been reported, a suitable model to interpret the speckle-pattern variation under perturbation is desirable but very challenging to be developed due to the various factors influencing the speckle pattern. In this work, a new methodology based on the finite element method (FEM) for modeling and optimizing fiber specklegram sensors (FSSs) is proposed. The numerical method allows computational visualization and quantification, in near field, of changes of a step multi-mode fiber (SMMF) specklegram, due to the application of a uniformly distributed force line (UDFL)...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27906290/polarization-variable-emitter-for-terahertz-time-domain-spectroscopy
#10
Dmitry S Bulgarevich, Makoto Watanabe, Mitsuharu Shiwa, Gudrun Niehues, Hideaki Kitahara, Masahiko Tani
We report on the progress in the development of linear polarization-variable multi-electrode emitters for terahertz time-domain spectroscopy. The results on its microfabrication, the finite element method modeling of appropriate bias distribution between electrodes, the finite-difference time-domain simulated spectral output, and actual experimental testing are presented. The rotation of the emitted terahertz field with linear polarization on an angle multiple of 45° can be achieved by synchronized bias and single polarizer rotations...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27906283/5kw-gtwave-fiber-amplifier-directly-pumped-by-commercial-976nm-laser-diodes
#11
Huan Zhan, Qinyong Liu, Yuying Wang, Weiwei Ke, Li Ni, Xiaolong Wang, Kun Peng, Cong Gao, Yuwei Li, Honghuan Lin, Jianjun Wang, Feng Jing, Aoxiang Lin
With home-made fiber perform and special fiber drawing & coating technique, a new-type of (3 + 1) GTWave fiber theoretically designed for bi-directional pump method, was successfully fabricated and justified of integrating multi-kW pump energy from commercial 976nm laser diodes. This (3 + 1) GTWave fiber amplifier demonstrated uniform absorption of pump light and easy thermal management characteristics along the whole fiber length. This amplifier is capable of simultaneously aggregating 5.19kW pump power at 976nm and finally generating 5...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27906258/optical-cryptosystem-based-on-single-pixel-encoding-using-the-modified-gerchberg-saxton-algorithm-with-a-cascaded-structure
#12
Wen Chen
In this paper, an optical cryptosystem is developed based on single-pixel encoding using the modified Gerchberg-Saxton algorithm with a cascaded structure. A series of random intensity-only patterns are pre-generated as principal security keys, and phase-only masks for optical encoding and decoding are generated by the modified Gerchberg-Saxton algorithm with a cascaded structure. Subsequently, a series of 1D intensity points, i.e., ciphertexts, are recorded by a single-pixel detector, which may provide a potential for establishing low-cost and compact security systems...
December 1, 2016: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/27906257/inverse-scattering-for-unbounded-fractally-corrugated-surfaces
#13
Lei Zhang
The phaseless inverse scattering of optical or electromagnetic waves from unbounded fractally corrugated surfaces are taken into account. The main characteristics of this inverse scattering problem are that only the phaseless scattered field is measured and the incident field is a tapered wave. In the previous recent works of the authors about the inverse scattering of rough surfaces, the cases of the Dirichlet boundary condition were considered [Inverse Prob.32, 085002 (2016)INPEEY0266-561110.1088/0266-5611/32/8/085002; Inverse Probl...
December 1, 2016: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/27906256/method-to-determine-the-degrees-of-consistency-in-experimental-datasets-of-perceptual-color-differences
#14
Samuel Morillas, Luis Gómez-Robledo, Rafael Huertas, Manuel Melgosa
We propose a fuzzy method to analyze datasets of perceptual color differences with two main objectives: to detect inconsistencies between couples of color pairs and to assign a degree of consistency to each color pair in a dataset. This method can be thought as the outcome of a previous one developed for a similar purpose [J. Mod. Opt.56, 1447 (2009)JMOPEW0950-034010.1080/09500340902944038], whose performance is compared with the proposed one. In this work, we present the results achieved using the dataset employed to develop the current CIE/ISO color-difference formula, CIEDE2000, but the method could be applied to any dataset...
December 1, 2016: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/27906170/generating-high-purity-cardiac-and-endothelial-derivatives-from-patterned-mesoderm-using-human-pluripotent-stem-cells
#15
Nathan J Palpant, Lil Pabon, Clayton E Friedman, Meredith Roberts, Brandon Hadland, Rebecca J Zaunbrecher, Irwin Bernstein, Ying Zheng, Charles E Murry
Human pluripotent stem cells (hPSCs) provide a valuable model for the study of human development and a means to generate a scalable source of cells for therapeutic applications. This protocol specifies cell fate efficiently into cardiac and endothelial lineages from hPSCs. The protocol takes 2 weeks to complete and requires experience in hPSC culture and differentiation techniques. Building on lessons taken from early development, this monolayer-directed differentiation protocol uses different concentrations of activin A and bone morphogenetic protein 4 (BMP4) to polarize cells into mesodermal subtypes that reflect mid-primitive-streak cardiogenic mesoderm and posterior-primitive-streak hemogenic mesoderm...
January 2017: Nature Protocols
https://www.readbyqxmd.com/read/27906168/immunofluorescent-antibody-staining-of-intact-drosophila-larvae
#16
Laurina Manning, Chris Q Doe
Antibody staining is a vital technique for studying the development of many model organisms, including Drosophila. Reliable protocols have long been available for antibody staining of Drosophila whole-mount embryos and dissected larvae. By contrast, methods for staining whole larvae have rarely been reported, are unreliable, and fail to work on large third-instar larvae. This has become a major limitation to understanding the role of multitissue interactions such as neural circuit formation and cell metastasis...
January 2017: Nature Protocols
https://www.readbyqxmd.com/read/27906131/the-mir-125-family-is-an-important-regulator-of-the-expression-and-maintenance-of-maternal-effect-genes-during-preimplantational-embryo-development
#17
Kyeoung-Hwa Kim, You-Mi Seo, Eun-Young Kim, Su-Yeon Lee, Jini Kwon, Jung-Jae Ko, Kyung-Ah Lee
Previously, we reported that Sebox is a new maternal effect gene (MEG) that is required for early embryo development beyond the two-cell (2C) stage because this gene orchestrates the expression of important genes for zygotic genome activation (ZGA). However, regulators of Sebox expression remain unknown. Therefore, the objectives of the present study were to use bioinformatics tools to identify such regulatory microRNAs (miRNAs) and to determine the effects of the identified miRNAs on Sebox expression. Using computational algorithms, we identified a motif within the 3'UTR of Sebox mRNA that is specific to the seed region of the miR-125 family, which includes miR-125a-5p, miR-125b-5p and miR-351-5p...
November 2016: Open Biology
https://www.readbyqxmd.com/read/27906100/an-isothermal-dna-amplification-method-for-detection-of-onchocerca-volvulus-infection-in-skin-biopsies
#18
Ole Lagatie, Michelle Merino, Linda Batsa Debrah, Alexander Y Debrah, Lieven J Stuyver
BACKGROUND: Diagnostic procedures for the diagnosis of infection with the nematode parasite Onchocerca volvulus are currently based on the microscopic detection of microfilariae in skin biopsies. Alternative approaches based on amplification of parasitic DNA in these skin biopsies are currently being explored. Mostly this is based on the detection of the O-150 repeat sequence using PCR based techniques. METHODS: An isothermal, loop-mediated amplification method has been designed using the mitochondrial O...
December 1, 2016: Parasites & Vectors
https://www.readbyqxmd.com/read/27906098/direct-reprogramming-of-urine-derived-cells-with-inducible-myod-for-modeling-human-muscle-disease
#19
Ellis Y Kim, Patrick Page, Lisa M Dellefave-Castillo, Elizabeth M McNally, Eugene J Wyatt
BACKGROUND: Cellular models of muscle disease are taking on increasing importance with the large number of genes and mutations implicated in causing myopathies and the concomitant need to test personalized therapies. Developing cell models relies on having an easily obtained source of cells, and if the cells are not derived from muscle itself, a robust reprogramming process is needed. Fibroblasts are a human cell source that works well for the generation of induced pluripotent stem cells, which can then be differentiated into cardiomyocyte lineages, and with less efficiency, skeletal muscle-like lineages...
September 15, 2016: Skeletal Muscle
https://www.readbyqxmd.com/read/27906041/implementation-of-the-better-2-program-a-qualitative-study-exploring-barriers-and-facilitators-of-a-novel-way-to-improve-chronic-disease-prevention-and-screening-in-primary-care
#20
Nicolette Sopcak, Carolina Aguilar, Mary Ann O'Brien, Candace Nykiforuk, Kris Aubrey-Bassler, Richard Cullen, Eva Grunfeld, Donna Patricia Manca
BACKGROUND: BETTER (Building on Existing Tools to Improve Chronic Disease Prevention and Screening in Primary Care) is a patient-based intervention to improve chronic disease prevention and screening (CDPS) for cardiovascular disease, diabetes, cancer, and associated lifestyle factors in patients aged 40 to 65. The key component of BETTER is a prevention practitioner (PP), a health care professional with specialized skills in CDPS who meets with patients to develop a personalized prevention prescription, using the BETTER toolkit and Brief Action Planning...
December 1, 2016: Implementation Science: IS
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