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https://www.readbyqxmd.com/read/29924787/-staged-treatment-of-a-multilevel-lesion-of-brachiocephalic-arteries-in-combination-with-coronary-and-valvular-pathology-of-the-heart
#1
M A Cherniavskiĭ, A A Gusev, D V Chernova, I V Iarkov, M L Gordeev
Prevention of neurological complications in cardiosurgical and reconstructive vascular surgery is one of the priority tasks of preserving ability to work and decreasing invalidization of patients in the postoperative period. Presented in the article is a clinical case report regarding multiple-stage treatment of a female patient with a combined aortic defect, coronary pathology, and a multilevel bilateral lesion of the brachiocephalic arteries. The first stage consisted in performing a hybrid operation, i. e...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/29924778/-comparative-3-year-results-of-phlebectomy-and-thermal-ablation-for-lower-limb-varicose-veins
#2
E P Burleva, S A Tiurin, O A Smirnov, R R Faskhiev
The study was aimed at comparing clinical and ultrasonographic results during 3 years of postoperative follow up of patients presenting with lower limb varicose veins (LLVV) and subjected to either surgical or thermal-ablation procedures for removal of pathological reflux along the great saphenous vein (GSV) within the femur The study included a total of 185 patients with clinical class C2-3 LLVV in the system of the GSV. The patients were divided into three groups: Group One consisted of 63 patients subjected to short stripping of the GSV trunk + treatment of the perforant veins (66...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/29923763/novel-haemodynamic-structures-in-the-human-glomerulus
#3
Christopher R Neal, Kenton Arkill, James Stephen Bell, Kai B Betteridge, David O Bates, C Peter Winlove, Andrew Hj Salmon, Steven J Harper
To investigate human glomerular structure under conditions of physiological perfusion we have analysed fresh and perfusion fixed normal human glomeruli at physiological hydrostatic and oncotic pressures using serial resin section reconstruction, confocal, multiphoton and electron microscope imaging. Afferent and efferent arterioles (21.5{plus minus}1.2µm and 15.9{plus minus}1.2µm diameter), recognised from vascular origins, lead into previously undescribed wider regions (43.2{plus minus}2.8 µm and 38.4{plus minus}4...
June 20, 2018: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/29923473/importance-of-transcatheter-closure-test-for-giant-ventricular-septal-defect-associated-with-pulmonary-hypertension-a-case-with-successful-surgical-repair-of-the-defect
#4
Xiaoke Shang, Rong Lu, Nianguo Dong
This is the first attempt to use a temporary occluder to close a giant perimembranous ventricular septal defect (32 mm), which obtains clinical evidence of good haemodynamics in patients with severe pulmonary hypertension. This may provide an alternative assessment to guide cardiac surgeons in determining a definitive treatment.
June 20, 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29921685/stepped-wedge-cluster-randomised-controlled-trial-to-assess-the-effectiveness-of-an-optimisation-strategy-for-general-anaesthesia-on-postoperative-morbidity-and-mortality-in-elderly-patients-the-opti-aged-study-a-study-protocol
#5
Serge Molliex, Sylvie Passot, Emmanuel Futier, Marlène Bonnefoi, Florence Rancon, Yannick Lemanach, Bruno Pereira
INTRODUCTION: Elderly patients constitute an increasingly large proportion of the high-risk surgical group. In adult patients, several specific intraoperative approaches such as cardiac output-guided haemodynamic therapy, depth of anaesthesia monitoring (DAM) or lung-protective ventilation (LPV) are designed to reduce postoperative mortality and surgical complications. However, none of these approaches has been specifically performed in the elderly, and no evaluation of a multimodal optimisation strategy for general anaesthesia has been achieved in this population...
June 19, 2018: BMJ Open
https://www.readbyqxmd.com/read/29921553/il-33-initiates-vascular-remodelling-in-hypoxic-pulmonary-hypertension-by-up-regulating-hif-1%C3%AE-and-vegf-expression-in-vascular-endothelial-cells
#6
Jie Liu, Wang Wang, Lei Wang, Shihao Chen, Bo Tian, Kewu Huang, Chris J Corrigan, Sun Ying, Wei Wang, Chen Wang
IL-33 may play a role in the vascular remodelling of hypoxic pulmonary hypertension (PH) but the precise mechanisms are still unclear. We hypothesized that hypoxia promotes expression of IL-33 and its receptor ST2 on vascular endothelial cells, which in turn leads to dysfunction of vascular endothelial cells and smooth muscle cells contributing to PH. Immunohistochemistry showed that immunoreactivity for IL-33 and ST2 was significantly increased in lung tissue of murine model of hypoxia-induced PH (HPH) and of subjects with bronchiectasis-PH...
June 16, 2018: EBioMedicine
https://www.readbyqxmd.com/read/29920539/clinical-phenotypes-and-outcomes-of-pulmonary-hypertension-due-to-left-heart-disease-role-of-the-pre-capillary-component
#7
Sergio Caravita, Andrea Faini, Sandy Carolino D'Araujo, Céline Dewachter, Laura Chomette, Antoine Bondue, Robert Naeije, Gianfranco Parati, Jean-Luc Vachiéry
BACKGROUND: In pulmonary hypertension (PH), both wedge pressure elevation (PAWP) and a precapillary component may affect right ventricular (RV) afterload. These changes may contribute to RV failure and prognosis. We aimed at describing the different haemodynamic phenotypes of patients with PH due to left heart disease (LHD) and at characterizing the impact of pulmonary haemodynamics on RV function and outcome PH-LHD. METHODS: Patients with PH-LHD were compared with treatment-naïve idiopathic/heritable pulmonary arterial hypertension (PAH, n = 35)...
2018: PloS One
https://www.readbyqxmd.com/read/29916728/quantitative-assessment-of-the-flow-distribution-in-the-branches-of-the-external-carotid-by-non-injected-flow-mri
#8
Jérémie Bettoni, Gwénaël Pagé, Anne-Virginie Salsac, Jean-Marc Constans, Sylvie Testelin, Bernard Devauchelle, Olivier Balédent, Stéphanie Dakpé
Owing to the lack of databases of blood flow distributions in the external carotid branches, surgeons currently rely on per-operative imaging and on their experience to choose the recipient vessels for microsurgical facial reconstructions. But, thanks to three-dimensional phase contrast angiography (PCA) and kinematic CINE phase contrast (PC) sequences, MRI technologies have the potential to provide quantitative anatomical and hemodynamic information without injection of contrast agent. Having developed and optimized PC-MRI sequences for the small facial vessels, our objective was to investigate the haemodynamic and blood flow distribution in the external carotid branches...
June 19, 2018: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/29912679/oral-indomethacin-versus-oral-ibuprofen-for-treatment-of-patent-ductus-arteriosus-a-randomised-controlled-study-in-very-low-birthweight-infants
#9
Varangthip Khuwuthyakorn, Chuleeporn Jatuwattana, Suchaya Silvilairat, Watcharee Tantiprapha
Background In low- and middle-income countries (LMIC), haemodynamically significant patent ductus arteriosus (hsPDA) is treated with oral indomethacin (IDC) and ibuprofen (IB) instead of intravenous formulations. No significant differences in efficacy have been reported. However, previous studies had small numbers of VLBW infants (<1500 g). Objective To evaluate the efficacy of oral IDC and IB for closing PDA in VLBW infants with a gestational age of 24-32 weeks. Methods This randomised controlled study enrolled 32 infants with hsPDA for treatment with either three doses of oral IDC or oral IB...
June 18, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/29910489/does-the-phase-of-the-menstrual-cycle-really-matter-to-anaesthesia
#10
Madhuri S Kurdi, Ashwini H Ramaswamy
The menstrual cycle is a physiological phenomenon that is accompanied by several hormonal fluctuations involving oestrogen and progesterone. Oestrogen and progesterone exert several physiological effects. There are many questions pertaining to the influence of the physiology of menstruation on anaesthesia. We attempted to find out whether the phase of the menstrual cycle can alter the physiological functions during anaesthesia, the perioperative management and outcomes. We performed a literature search in Google Scholar, PubMed and Cochrane databases for original and reviewed articles on the phases of the menstrual cycle and their relation to anaesthesia-related physiological parameters to find an answer to these questions...
May 2018: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/29909817/technical-factors-are-associated-with-complications-and-repeat-intervention-in-neonates-undergoing-transcatheter-right-ventricular-decompression-for-pulmonary-atresia-and-intact-ventricular-septum-results-from-the-congenital-catheterisation-research-collaborative
#11
Christopher J Petit, Athar M Qureshi, Andrew C Glatz, Michael S Kelleman, Courtney E McCracken, R Allen Ligon, Namrita Mozumdar, Wendy Whiteside, Asra Khan, Bryan H Goldstein
BACKGROUND: Transcatheter right ventricle decompression in neonates with pulmonary atresia and intact ventricular septum is technically challenging, with risk of cardiac perforation and death. Further, despite successful right ventricle decompression, re-intervention on the pulmonary valve is common. The association between technical factors during right ventricle decompression and the risks of complications and re-intervention are not well described. METHODS: This is a multicentre retrospective study among the participating centres of the Congenital Catheterization Research Collaborative...
June 18, 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29909466/successful-non-operative-management-of-haemodynamically-unstable-traumatic-splenic-injuries-4-year-case-series-in-a-uk-major-trauma-centre
#12
Richard A Armstrong, Andrew Macallister, Benjamin Walton, Julian Thompson
PURPOSE: Management of traumatic splenic injury may be operative or non-operative (including embolization and conservative management). Traditionally, haemodynamic instability has been an indication for operative intervention. We aimed to report our experience of managing traumatic splenic injury at a regional major trauma centre in the UK over a 4-year period, with a particular focus on the non-operative management (NOM) of haemodynamically unstable patients. METHODS: All patients with splenic injuries admitted to North Bristol NHS Trust from April 2012 to March 2016 were included...
June 16, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29908713/current-indications-for-the-intra-aortic-balloon-pump-the-cp-garo-registry
#13
Benoit Helleu, Vincent Auffret, Marc Bedossa, Martine Gilard, Vincent Letocart, Stephan Chassaing, Denis Angoulvant, Philippe Commeau, Grégoire Range, Fabrice Prunier, Remi Sabatier, Emmanuelle Filippi, Régis Delaunay, Dominique Boulmier, Hervé Le Breton, Guillaume Leurent
BACKGROUND: Intra-aortic balloon pumps (IABPs) have been used routinely since the 1970s. Recently, large randomized trials failed to show that IABP therapy has meaningful benefit, and international recommendations downgraded its place, particularly in cardiogenic shock. AIMS: The aim of this registry was to describe the contemporary use of IABP therapy, in light of these new data. METHODS: This prospective multicentre registry included 172 patients implanted with an IABP in 19 French cardiac centres in 2015...
June 13, 2018: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/29905796/heart-failure-with-preserved-ejection-fraction-from-mechanisms-to-therapies
#14
Carolyn S P Lam, Adriaan A Voors, Rudolf A de Boer, Scott D Solomon, Dirk J van Veldhuisen
This review aims to provide a translational perspective on recent developments in heart failure with preserved ejection fraction (HFpEF), linking mechanistic insights to potential therapies. A key concept in this review is that HFpEF is a haemodynamic condition wherein the heart fails to keep up with the circulatory demands of the body, or does so at the expense of raised left ventricular filling pressures. We, therefore, propose that the 'final common pathway' for development of congestion, i.e. basic haemodynamic mechanisms of increased left ventricular end-diastolic pressure, left atrial hypertension, pulmonary venous congestion, and plasma volume expansion, represents important initial targets for therapy in HFpEF...
June 13, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29903693/mechanical-circulatory-support-in-patients-with-cardiogenic-shock-in-intensive-care-units-a-position-paper-of-the-unit%C3%A3-de-soins-intensifs-de-cardiologie-group-of-the-french-society-of-cardiology-endorsed-by-the-groupe-ath%C3%A3-rome-et-cardiologie-interventionnelle
#15
REVIEW
Laurent Bonello, Clement Delmas, Guillaume Schurtz, Guillaume Leurent, Eric Bonnefoy, Nadia Aissaoui, Patrick Henry
Cardiogenic shock (CS) is a major challenge in contemporary cardiology. Despite a better understanding of the pathophysiology of CS, its management has only improved slightly. The prevalence of CS has remained stable over the past decade, but its outcome has seen few improvements, with the 1-month mortality rate still in the range of 40-60%. Inotropes and vasopressors are the first-line therapies for CS, but they are associated with significant hazards, and have well-known deleterious effects. Furthermore, a significant number of patients develop refractory CS with haemodynamic instability, causing critical organ hypoperfusion and/or pulmonary congestion, despite increasing doses of catecholamines...
June 11, 2018: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/29902830/-extracorporeal-membrane-oxygenation-in-thoracic-surgery-lung-transplantation
#16
Clemens Aigner, Alexis Slama, Daniel Valdivia
Extracorporeal membrane oxygenation (ECMO) has become a routine method in thoracic surgery. Recent developments in lung transplantation have led to its widespread acceptance. Firstly, ECMO is increasingly being used to bridge patients to transplantation. The best results in this setting have been described with "awake ECMO". Secondly, ECMO has replaced cardio-pulmonary bypass as the intraoperative standard device in most centres and is used for treatment and prevention of primary graft dysfunction...
June 14, 2018: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/29902538/a-multicentre-observational-study-on-management-of-general-anaesthesia-in-elderly-patients-at-high-risk-of-postoperative-adverse-outcomes
#17
Serge Molliex, Sylvie Passot, Jerome Morel, Emmanuel Futier, Jean Yves Lefrant, Jean Michel Constantin, Yannick Le Manach, Bruno Pereira
INTRODUCTION: in elderly patients, goal directed haemodynamic therapy (GDHT), depth of anaesthesia monitoring and lung-protective ventilation have been shown to improve postoperative outcomes. The aim of this study was to evaluate current practices concerning strategies of anaesthesia optimisation in patients aged ≥ 75 years. PATIENTS AND METHODS: a multicentre observational study was performed from February to May 2015 in 23 French academic centres. On 30 consecutive days in each centre, patients ≥ 75 years with at least one major co-morbidity undergoing elective or emergency procedures (femoral-neck fractures surgery, intraperitoneal abdominal surgery or vascular surgery) were included...
June 11, 2018: Anaesthesia, Critical Care & Pain Medicine
https://www.readbyqxmd.com/read/29895487/virtual-functional-assessment-of-coronary-stenoses-using-intravascular-ultrasound-imaging-a-proof-of-concept-pilot-study
#18
Panagiotis K Siogkas, Michail I Papafaklis, Lampros Lakkas, Themis P Exarchos, Dimitri Karmpaliotis, Ziad A Ali, Gualtiero Pelosi, Oberdan Parodi, Christos S Katsouras, Dimitrios I Fotiadis, Lampros K Michalis
AIMS: We aimed to investigate the performance of virtual functional assessment of coronary stenoses using intravascular ultrasound (IVUS)-based three-dimensional (3D) coronary artery reconstruction against the invasively measured fractional flow reserve (FFR). METHODS AND RESULTS: Twenty-two patients with either typical symptoms of stable angina or a positive stress test, who underwent IVUS and FFR, were included in this study. Five patients presented FFR values lower than the 0...
March 2, 2018: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29895486/left-ventricular-assist-devices-in-pulmonary-hypertension-group-2-with-significantly-elevated-pulmonary-vascular-resistance-a-bridge-to-cure
#19
Ahmed M Selim, Lalit Wadhwani, Adam Burdorf, Eugenia Raichlin, Brian Lowes, Ronald Zolty
BACKGROUND: Pulmonary hypertension secondary to left heart disease (WHO Group 2) is a known risk factor in patients with heart failure. The favourable effect of left ventricular assist devices (LVAD) on pulmonary hypertension has been demonstrated before, although this effect has not been well-studied in advanced pulmonary arterial bed disease with a significant elevation in pulmonary vascular resistance. METHODS: We reviewed the records of 258 LVAD patients in our institution...
May 18, 2018: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29895426/sacubitril-valsartan-can-haemodynamic-monitoring-help-with-up-take
#20
EDITORIAL
Andrew J Stewart Coats
No abstract text is available yet for this article.
May 20, 2018: International Journal of Cardiology
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