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https://www.readbyqxmd.com/read/28645001/a-role-for-visceral-feedback-and-interoception-in-feelings-of-knowing
#1
Chris M Fiacconi, Jane E Kouptsova, Stefan Köhler
Guided by the framework that autonomic feedback shapes emotional experience and other feeling states, we asked whether feeling-of-knowing (FOK) judgments may be influenced by visceral information through interoception. Participants performed a FOK task for previously studied face-name pairs while changes in cardiovascular and facial muscle activity were recorded. Previously studied face cues for which the corresponding name could not be recalled elicited an increased cardiac rate relative to novel face cues...
June 20, 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/28644975/a-neural-blood-pressure-marker-for-bioelectronic-medicines-for-treatment-of-hypertension
#2
Cristian Sevcencu, Thomas N Nielsen, Johannes J Struijk
A novel therapeutic approach for treating resistant hypertension could be the use of bioelectronic medicines to achieve blood pressure (BP) control in implanted patients by closed-loop stimulation of the left vagus nerve (LVN). However, such a technology would require an implantable BP marker, which is not available yet. As it is known that the LVN conducts afferent BP-related signals, this study aimed to investigate if such signals could be recorded with implantable means and used to derive BP markers. The present experiments were performed in anesthetized pigs subjected to a transient or stable BP increase induced by adrenaline administration...
June 17, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28644711/screening-for-squamous-cell-anal-cancer-in-hiv-positive-patients-a-five-year-experience
#3
Chiara Santorelli, Cosimo Alex Leo, Jonathan D Hodgkinson, Franco Baldelli, Francesco Cantarella, Emanuel Cavazzoni
AIM: Potential screening modalities for early diagnosis of squamous cell anal cancer (SCC) in HIV patients include digital anorectal examination (DARE), anal Papanicolaou testing (Pap test), human papilloma virus (HPV) co-testing, and high-resolution anoscopy. The aim of this study was to demonstrate the results of a five-year screening program for SCC in HIV patients. MATERIALS AND METHODS: We conducted a retrospective study on 204 HIV patients who underwent a screening program for SCC from October 2010 to January 2015...
June 23, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28644180/mucosal-healing-in-clinical-practice-a-single-center-pediatric-ibd-experience
#4
Savini L Santha, Prabhu R Shankar, Anqi Pan, Bess Schoen, Subra Kugathasan, Cary G Sauer
BACKGROUND: Mucosal healing (MH) is associated with improved clinical outcomes in patients with Crohn's disease (CD) and ulcerative colitis (UC). MH as a target for treatment has been suggested, although there is little pediatric data. The goal of this study was to evaluate MH in clinical practice in pediatric patients with inflammatory bowel disease in clinical remission. METHODS: A retrospective review of electronic health record data was performed on all patients with CD or UC who underwent at least 2 colonoscopies from 2010 through 2016...
June 20, 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28643840/synchronization-of-excitable-cardiac-cultures-of-different-origin
#5
N N Agladze, O V Halaidych, V A Tsvelaya, T Bruegmann, C Kilgus, P Sasse, K I Agladze
In the present work, we investigated the synchronization of electrical activity in cultured cardiac cells of different origin put in direct contact. In the first set of experiments synchronization was studied in the primary culture cells of neonatal rats taken at different developmental ages, and in the second - in the neonatal rat cardiomyocytes and HL-1 cells. The electrical excitation of cells was recorded using the calcium transient marker Fluor-4. In the confluent cell layers created with the aid of a specially devised mask, the excitation waves and their propagation between areas occupied by cells of different origin were observed...
June 23, 2017: Biomaterials Science
https://www.readbyqxmd.com/read/28642565/no-evidence-available-on-best-therapies-for-postextraction-haemorrhage
#6
Analia Veitz-Keenan, James Keenan
Data sourcesThe review searched for published and ongoing trials in several databases with no restrictions on language or date of publication which included the Cochrane Oral Health Group Trials, Central Register of Controlled Trials, Medline, CINAHL, Embase, WHO Clinical Trials Registry Platform and clinical trial.gov.Study selectionRandomised clinical trials were considered that evaluated any intervention compared with another or with placebo for treating postoperative bleeding (PEB), post extraction. The primary outcome measures sought were: bleeding, amount of blood loss and cessation time required to control bleeding...
June 23, 2017: Evidence-based Dentistry
https://www.readbyqxmd.com/read/28642213/development-of-a-web-based-intervention-for-addressing-distress-in-caregivers-of-patients-receiving-stem-cell-transplants-formative-evaluation-with-stakeholder-interviews-and-focus-groups
#7
Nicole Amoyal Pensak, Tanisha Joshi, Teresa Simoneau, Kristin Kilbourn, Alaina Carr, Jean Kutner, Mark L Laudenslager
BACKGROUND: Caregivers of cancer patients experience significant burden and distress including depression and anxiety. We previously demonstrated the efficacy of an eight session, in-person, one-on-one stress management intervention to reduce distress in caregivers of patients receiving allogeneic hematopoietic stem cell transplants (allo-HSCT). OBJECTIVE: The objective of this study was to adapt and enhance the in-person caregiver stress management intervention to a mobilized website (eg, tablet, smartphone, or computer-based) for self-delivery in order to enhance dissemination to caregiver populations most in need...
June 22, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28641929/initiation-and-engagement-with-methadone-treatment-among-pregnant-and-postpartum-women
#8
Kristin M Mattocks, Robin Clark, Linda Weinreb
PURPOSE: The purpose of this study was to explore perceptions of experiences and challenges with methadone maintenance treatment (MMT) and obstetrical care among pregnant and postpartum women enrolled in a methadone maintenance program. RESEARCH DESIGN: The study featured a grounded theory approach including two focus groups with pregnant and postpartum methadone users at a methadone maintenance clinic in Worcester, Massachusetts. Two research team members conducted and recorded focus groups, which took approximately 45 minutes to 1 hour...
June 19, 2017: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/28641170/efficacy-and-safety-of-eslicarbazepine-acetate-monotherapy-for-partial-onset-seizures-experience-from-a-multicenter-observational-study
#9
Rafael Toledano, Camilo Espinosa Jovel, Adolfo Jiménez-Huete, Pau Giner Bayarri, Dulce Campos, Elena López Gomariz, Beatriz González Giráldez, Irene García-Morales, Mercé Falip, Paula Martínez Agredano, Susana Palao, María José Aguilar Amat Prior, María Rosa Querol Pascual, Francisco José Navacerrada, Francisco Javier López González, Joaquín Ojeda, Aránzazu Alfaro Sáez, Pedro Emilio Bermejo, Antonio Gil-Nagel
Eslicarbazepine acetate (ESL, Aptiom™) is a once-daily anticonvulsant, approved as adjunctive treatment of partial-onset seizures (POS). Historical-controlled trials investigating the use of ESL as monotherapy have demonstrated a favorable efficacy and tolerability profile in patients with POS. This prospective, non-interventional study recruited POS patients in 17 hospitals in Spain. After a 3-month baseline period, ESL therapy was initiated as 400mg QD and up-titrated to an optimal maintenance dose based on clinical response and tolerance...
June 19, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28641089/combined-time-lapse-magnetic-resonance-imaging-and-modeling-to-investigate-colloid-deposition-and-transport-in-porous-media
#10
Alizée P Lehoux, Pamela Faure, François Lafolie, Stéphane Rodts, Denis Courtier-Murias, Philippe Coussot, Eric Michel
Colloidal particles can act as vectors of adsorbed pollutants in the subsurface, or be themselves pollutants. They can reach the aquifer and impair groundwater quality. The mechanisms of colloid transport and deposition are often studied in columns filled with saturated porous media. Time-lapse profiles of colloid concentration inside the columns have occasionally been derived from magnetic resonance imaging (MRI) data recorded in transport experiments. These profiles are valuable, in addition to particle breakthrough curves (BTCs), for testing and improving colloid transport models...
June 14, 2017: Water Research
https://www.readbyqxmd.com/read/28640786/a-standardized-approach-for-transfusion-medicine-support-in-patients-with-morbidly-adherent-placenta
#11
Anil K Panigrahi, Amanda Yeaton-Massey, Sara Bakhtary, Jennifer Andrews, Deirdre J Lyell, Alexander J Butwick, Lawrence Tim Goodnough
BACKGROUND: The incidence of placenta accreta (PA) has increased from 0.8 to 3.0 in 1000 pregnancies, driven by increased rates of cesarean deliveries (32.2% in 2014) of births in the United States. The average blood loss for a delivery complicated by PA ranges from 2000 to 5000 mL, frequently requiring substantial transfusion medicine support. We report our own institutional multidisciplinary approach for managing such patients, along with transfusion medicine outcomes, in this setting over a 5-year period...
June 20, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28640166/missing-documentation-in-breast-cancer-survivors-genitourinary-syndrome-of-menopause
#12
Elise D Cook, Elena I Iglehart, George Baum, Leslie L Schover, Lonzetta L Newman
OBJECTIVE: Breast cancer survivors often take hormonal treatments to prevent the recurrence of breast cancer, particularly aromatase inhibitors that can worsen the symptoms of genitourinary syndrome of menopause (GSM) such as dyspareunia, dysuria, and urinary incontinence, all of which may adversely affect survivors' quality of life. Few breast cancer survivors experiencing GSM receive adequate assessment or treatment. METHODS: In this descriptive study, we reviewed medical records for documented GSM and any treatments administered or referrals for treatment in 800 female patients who visited the Breast Cancer Survivorship Clinic at a comprehensive cancer center between July 1, 2010 and June 30, 2011, either at least 5 years after completion of treatment for invasive breast cancer or at least 6 months after completion of treatment for ductal carcinoma in situ...
June 19, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28639824/upside-down-perceived-space-affects-object-based-attention
#13
Frank Papenmeier, Hauke S Meyerhoff, Alisa Brockhoff, Georg Jahn, Markus Huff
Object-based attention influences the subjective metrics of surrounding space. However, does perceived space influence object-based attention, as well? We used an attentive tracking task that required sustained object-based attention while objects moved within a tracking space. We manipulated perceived space through the availability of depth cues and varied the orientation of the tracking space. When rich depth cues were available (appearance of a voluminous tracking space), the upside-down orientation of the tracking space (objects appeared to move high on a ceiling) caused a pronounced impairment of tracking performance compared with an upright orientation of the tracking space (objects appeared to move on a floor plane)...
July 2017: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/28639823/our-own-action-kinematics-predict-the-perceived-affective-states-of-others
#14
Rosanna Edey, Daniel Yon, Jennifer Cook, Iroise Dumontheil, Clare Press
Our movement kinematics provide useful cues about our affective states. Given that our experiences furnish models that help us to interpret our environment, and that a rich source of action experience comes from our own movements, in the present study, we examined whether we use models of our own action kinematics to make judgments about the affective states of others. For example, relative to one's typical kinematics, anger is associated with fast movements. Therefore, the extent to which we perceive anger in others may be determined by the degree to which their movements are faster than our own typical movements...
July 2017: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/28639821/perceived-discrimination-associations-with-physical-and-cognitive-function-in-older-adults
#15
Aparna Shankar, Petra Hinds
OBJECTIVES: Perceived discrimination has been associated with poor physical and psychological health. There is limited research examining perceived discrimination in older adults, and its effects on health in later life. The aim of this study is to extend research in this area by examining longitudinal associations between reported everyday discrimination and physical and cognitive function in older adults. METHOD: The present study uses a national sample of 4,886 community-dwelling individuals aged 60 years and older from the English Longitudinal Study of Ageing...
June 22, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/28639810/overstated-evidence-for-short-term-effects-of-violent-games-on-affect-and-behavior-a-reanalysis-of-anderson-et-al-2010
#16
Joseph Hilgard, Christopher R Engelhardt, Jeffrey N Rouder
Violent video games are theorized to be a significant cause of aggressive thoughts, feelings, and behaviors. Important evidence for this claim comes from a large meta-analysis by Anderson and colleagues (2010), who found effects of violent games in experimental, cross-sectional, and longitudinal research. In that meta-analysis, the authors argued that there is little publication or analytic bias in the literature, an argument supported by their use of the trim-and-fill procedure. In the present manuscript, we reexamine their meta-analysis using a wider array of techniques for detecting bias and adjusting effect sizes...
July 2017: Psychological Bulletin
https://www.readbyqxmd.com/read/28639804/reflective-functioning-physiological-reactivity-and-overcontrol-in-mothers-links-with-school-aged-children-s-reflective-functioning
#17
Jessica L Borelli, Kajung Hong, Hannah F Rasmussen, Patricia A Smiley
Theorists argue that parental reflective functioning (PRF) is activated in response to emotions, potentially supporting parenting sensitivity even when arousal is high. That is, when parents become emotionally reactive when interacting with their children, those who can use PRF to understand their children's mental states should be able to parent sensitively, which, in turn, should promote children's ability to understand their own mental states. We test this theory by examining whether, in the face of physiological reactivity, mothers' PRF inhibits one form of parenting insensitivity, overcontrol (OC), and whether this process in turn predicts children's RF...
June 22, 2017: Developmental Psychology
https://www.readbyqxmd.com/read/28639799/aging-and-confidence-judgments-in-item-recognition
#18
Chelsea Voskuilen, Roger Ratcliff, Gail McKoon
We examined the effects of aging on performance in an item-recognition experiment with confidence judgments. A model for confidence judgments and response time (RTs; Ratcliff & Starns, 2013) was used to fit a large amount of data from a new sample of older adults and a previously reported sample of younger adults. This model of confidence judgments allows us to distinguish between changes evidence from memory and changes in decision-related components and it accounts for both RT distributions and response proportions...
June 22, 2017: Journal of Experimental Psychology. Learning, Memory, and Cognition
https://www.readbyqxmd.com/read/28639797/the-dark-side-of-fluency-fluent-names-increase-drug-dosing
#19
Simone Dohle, Amanda K Montoya
Prior research has demonstrated that high processing fluency influences a wide range of evaluations and behaviors in a positive way. But can high processing fluency also lead to potentially hazardous medical behavior? In 2 controlled experiments, we demonstrate that increasing the fluency of pharmaceutical drug names increases drug dosage. Experiment 1 shows that drugs with fluent names are perceived as safer than those with disfluent names and this effect increases drug dosage for both synthetically produced and herbal drugs...
June 22, 2017: Journal of Experimental Psychology. Applied
https://www.readbyqxmd.com/read/28639792/emodiversity-and-biomarkers-of-inflammation
#20
Anthony D Ong, Lizbeth Benson, Alex J Zautra, Nilam Ram
There is growing evidence that inflammatory responses may help to explain how emotions get "under the skin" to influence disease susceptibility. Moving beyond examination of individuals' average level of emotion, this study examined how the breadth and relative abundance of emotions that individuals experience-emodiversity-is related to systemic inflammation. Using diary data from 175 adults aged 40 to 65 who provided end-of-day reports of their positive and negative emotions over 30 days, we found that greater diversity in day-to-day positive emotions was associated with lower circulating levels of inflammation (indicated by IL-6, CRP, fibrinogen), independent of mean levels of positive and negative emotions, body mass index, anti-inflammatory medications, medical conditions, personality, and demographics...
June 22, 2017: Emotion
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