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Maria Fragala-Pinkham, Andrew Fehlner
No abstract text is available yet for this article.
April 2018: Pediatric Physical Therapy
Giulia Ognibene, Salvatore Mannino, Maria Elena Fragalà, Gianluca Cicala
Electrospun veils from copolyethersulfones (coPES) were prepared as soluble interlaminar veils for carbon fiber/epoxy composites. Neat, resin samples were impregnated into coPES veils with unmodified resin, while dry carbon fabrics were covered with electrospun veils and then infused with the unmodified epoxy resin to prepare reinforced laminates. The thermoplastic content varied from 10 wt% to 20 wt%. TGAP epoxy monomer showed improved and fast dissolution for all the temperatures tested. The unreinforced samples were cured first at 180 °C for 2 h and then were post-cured at 220 °C for 3 h...
March 9, 2018: Materials
Seok-Won Kang, Joe Fragala, Su-Ho Kim, Debjyoti Banerjee
This paper presents a design optimization method based on theoretical analysis and numerical calculations, using a commercial multi-physics solver (e.g., ANSYS and ESI CFD-ACE+), for a 3D continuous model, to analyze the bending characteristics of an electrically heated bimorph microcantilever. The results from the theoretical calculation and numerical analysis are compared with those measured using a CCD camera and magnification lenses for a chip level microcantilever array fabricated in this study. The bimorph microcantilevers are thermally actuated by joule heating generated by a 0...
November 1, 2017: Sensors
Maren S Fragala, Caixia Bi, Michael Chaump, Harvey W Kaufman, Martin H Kroll
OBJECTIVES: Physical exercise may affect levels of blood-based biomarkers. However, exercise status is seldom considered in the interpretation of laboratory results. This study reports the associations between habitual exercise participation and clinical laboratory test results. METHODS: The effects of days per week of aerobic and strength exercise participation on laboratory test results for 26 biomarkers in young adults aged 18 to 34 years (n = 80,111) were evaluated using percentile distribution analyses and multivariate regression...
2017: PloS One
Jane E O'Brien, Helene M Dumas, Maria A Fragala-Pinkham, Jay G Berry
OBJECTIVES: Of all hospitalized children, those with medical complexity have the highest likelihood of hospital readmission. Post-acute hospital care could potentially help stabilize the health of these children. We examined the frequency of acute care hospital admissions after discharge home from a post-acute care hospital (PACH). METHODS: A retrospective cohort analysis of 448 children with medical complexity discharged from a PACH from January 1, 2010, to December 31, 2015, with the main outcomes of acute care hospital readmissions 0 to 30 and 31 to 90 days after discharge home from a PACH...
October 12, 2017: Hospital Pediatrics
Guy Fragala, Manon Labreche, Patti Wawzynieki
OBJECTIVES: Ambulatory care is a rapidly growing segment of overall healthcare delivery and populations seen in ambulatory care settings are aging resulting in many patients with mobility limitations. Mounting a fixed height examination table can present a challenge to a patient with mobility limitations and may be somewhat difficult for the general patient population. This study sought to investigate potential benefits to the patient which might be achieved through introduction of height adjustable examination tables...
September 2017: Journal of Patient Experience
Annalinda Contino, Giuseppe Maccarrone, Maria E Fragalà, Luca Spitaleri, Antonino Gulino
Gold nanoparticles show important properties owing to their electronic structures. A limitation of some gold nanoparticles is that they either show surface plasmons or luminescence. The increase in size of the gold nanoparticles, and the appearance of the surface plasmons may result in the disappearance of luminescence. The aim of our study is the nanoscale assembly of Au nanoparticles on a monolayer of porphyrin molecules anchored to functionalized inorganic surfaces. This functional architecture not only exhibits a strong surface plasmon due to the gold nanoparticles, but also a strong luminescence signal from the porphyrin molecules...
October 20, 2017: Chemistry: a European Journal
Elaine C Lee, Maren S Fragala, Stavros A Kavouras, Robin M Queen, John Luke Pryor, Douglas J Casa
Biomarker discovery and validation is a critical aim of the medical and scientific community. Research into exercise and diet-related biomarkers aims to improve health, performance, and recovery in military personnel, athletes, and lay persons. Exercise physiology research has identified individual biomarkers for assessing health, performance, and recovery during exercise training. However, there are few recommendations for biomarker panels for tracking changes in individuals participating in physical activity and exercise training programs...
October 2017: Journal of Strength and Conditioning Research
William J Kraemer, Mary J Kennett, Andrea M Mastro, Roger J McCarter, Connie J Rogers, William H DuPont, Shawn D Flanagan, William J Turbitt, Maren S Fragala, Emily M Post, Wesley C Hymer
OBJECTIVE: The consequences of age-related decline in the somatotropic axis of humans are complex and remain largely unresolved. We tested the hypothesis that hGH measurements of plasma by bioassay vs immunoassay from samples obtained from free-living, elderly individuals would reveal a dichotomy in GH activities that are correlated with the functional status of the donors, i.e. their healthspan. DESIGN: Forty-one men and women of advanced age (men: N=16, age, 80...
June 2017: Growth Hormone & IGF Research
Benjamin J Shore, Benjamin G Allar, Patricia E Miller, Travis H Matheney, Brian D Snyder, Maria A Fragala-Pinkham
Background: The Pediatric Evaluation of Disability Inventory-Computer Adaptive Test (PEDI-CAT) is a new clinical assessment for children and youth from birth through 20 years of age. Objective: To determine the discriminant validity of the PEDI-CAT according to the Gross Motor Function Classification System (GMFCS) and Manual Ability Classification System (MACS) in children with cerebral palsy (CP). Design: A prospective convenience cross-sectional sample of 101 school-age children with CP was stratified by GMFCS level...
June 1, 2017: Physical Therapy
William H DuPont, William J Kraemer, Bradley C Nindl, Elaine C Lee, Maren S Fragala, Disa L Hatfield, Lydia K Caldwell, Emily M Post, Matthew K Beeler, Jeff S Volek, Carl M Maresh
Due to the important interactions of proenkephalin fragments (e.g., proenkephalin [107-140] Peptide F) to enhance activation of immune cells and potentially combat pain associated with exercise-induced muscle tissue damage, we examined the differential plasma responses of Peptide F to different exercise training programs. Participants were tested pre-training (T1), and after 8 weeks (T2) of training. Fifty-nine healthy women were matched and then randomly assigned to one of four groups: heavy resistance strength training (STR, n=18), high intensity endurance training (END, n=14), combined strength and endurance training (CMB, n=17), or control (CON, n=10)...
May 2017: Peptides
Rosaly Correa-de-Araujo, Michael O Harris-Love, Iva Miljkovic, Maren S Fragala, Brian W Anthony, Todd M Manini
A growing body of scientific literature suggests that not only changes in skeletal muscle mass, but also other factors underpinning muscle quality, play a role in the decline in skeletal muscle function and impaired mobility associated with aging. A symposium on muscle quality and the need for standardized assessment was held on April 28, 2016 at the International Conference on Frailty and Sarcopenia Research in Philadelphia, Pennsylvania. The purpose of this symposium was to provide a venue for basic science and clinical researchers and expert clinicians to discuss muscle quality in the context of skeletal muscle function deficit and other aging-related muscle dysfunctions...
2017: Frontiers in Physiology
Helene M Dumas, Maria A Fragala-Pinkham, Elaine L Rosen, Eric Folmar
PURPOSE: To examine differences in physical therapy dosing frequency recommendations based on children's characteristics and to describe types of intervention recommended at postacute hospital admission. METHODS: Demographic and clinical information, recommended physical therapy intervention frequency, and intervention types were collected for all admissions from April 1, 2015, to March 1, 2016. Differences across 2 groups, children with recommendations for "less" (≤3x/wk) or "more" (≥4x/wk) frequent therapy, were examined...
January 2017: Pediatric Physical Therapy
Meysam Roostaei, Hamzeh Baharlouei, Hamidreza Azadi, Maria A Fragala-Pinkham
AIMS: To review the literature on the effects of aquatic intervention on gross motor skills for children with cerebral palsy (CP). DATA SOURCES: Six databases were searched from inception to January 2016. REVIEW METHODS: Aquatic studies for children aged 1-21 years with any type or CP classification and at least one outcome measuring gross motor skills were included. Information was extracted on study design, outcomes, and aquatic program type, frequency, duration, and intensity...
October 20, 2017: Physical & Occupational Therapy in Pediatrics
Giuseppe Trusso Sfrazzetto, Salvatrice Millesi, Andrea Pappalardo, Gaetano A Tomaselli, Francesco P Ballistreri, Rosa Maria Toscano, Ignazio Fragalà, Antonino Gulino
A uranyl complex monolayer that easily allows the optical detection of a nerve gas simulant, namely, dimethyl methylphosphonate, is reported. Both UV/Vis spectroscopy and photoelectron data confirm that the functional hybrid material coordinates a Lewis base by means of the P=O group, which interacts with the uranium equatorial site available for complexation.
January 31, 2017: Chemistry: a European Journal
Helene M Dumas, Maria A Fragala-Pinkham, Elaine L Rosen, Jane E O'Brien
PURPOSE: To assess construct (convergent and divergent) validity of the Pediatric Evaluation of Disability Inventory Computer Adaptive Test (PEDI-CAT) in a sample of children with complex medical conditions. METHOD: Demographics, clinical information, PEDI-CAT normative score, and the Post-Acute Acuity Rating for Children (PAARC) level were collected for all post-acute hospital admissions (n = 110) from 1 April 2015 to 1 March 2016. Correlations between the PEDI-CAT Daily Activities, Mobility, and Social/Cognitive domain scores for the total sample and across three age groups (infant, preschool, and school-age) were calculated...
September 19, 2016: Disability and Rehabilitation
Maria A Fragala-Pinkham, Helene M Dumas, Kelly A Lombard, Jane E O'Brien
PURPOSE: Responsiveness of the PEDI-CAT Mobility, Daily Activities, and Social/Cognitive domains and Wheelchair subdomain was evaluated for youth admitted to a pediatric post-acute care hospital. METHODS: Inpatients ages 2-21 years, with a length of stay of ≥ 5 days and with both admission and discharge scores were included. The difference between mean admission and discharge PEDI-CAT scaled scores were analyzed using paired t-tests. Effect sizes, standard response means (SRMs), and minimal detectable change values were calculated...
September 2, 2016: Journal of Pediatric Rehabilitation Medicine
Simona Filice, Giuseppe Compagnini, Roberto Fiorenza, Salvatore Scirè, Luisa D'Urso, Maria Elena Fragalà, Paola Russo, Enza Fazio, Silvia Scalese
We have measured the photocatalytic water splitting activity of several titania colloids, modified by nanosecond pulsed laser irradiation. Photocatalysis has been tested using UV and visible light. We have found that laser irradiation increases the hydrogen production efficiency up to a factor of three for anatase, rutile and P25. A hydrogen production rate as high as 30mmolg(-1)h(-1) has been obtained with good stability, tested by repeated runs. The chemical and morphological properties of the nanoparticles have been studied by electron microscopy, X-ray photoelectron spectroscopy and Raman spectroscopy, showing that laser irradiation promotes the formation of disordered surface state and lattice distortion which could be responsible for the observed enhanced photocatalytic activity...
March 1, 2017: Journal of Colloid and Interface Science
A Di Mauro, R Randazzo, S F Spanò, G Compagnini, M Gaeta, L D'Urso, R Paolesse, G Pomarico, C Di Natale, V Villari, N Micali, M E Fragalà, A D'Urso, R Purrello
Graphene oxide (GO) is one of the most appealing bidimensional materials able to interact non-covalently with achiral molecules and to act as chiral inducers. Vortexes can tune chirality and, consequently transfer a specific handedness to non-covalent host molecules, either when dispersed in water or when deposited on a solid surface.
November 18, 2016: Chemical Communications: Chem Comm
Massimiliano Gaeta, Ivan Pietro Oliveri, Maria Elena Fragalà, Salvatore Failla, Alessandro D'Urso, Santo Di Bella, Roberto Purrello
Herein, we exploit the induction of chirality by chiral Zn(ii) Schiff-base complexes, followed by their spontaneous dissociation in aqueous solution, providing for the first time a possibility of overcoming the template removal steps, to demonstrate memorization of chirality in porphyrin hetero-aggregates.
June 30, 2016: Chemical Communications: Chem Comm
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