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Acute kindey injury

Daniel Hertzberg, Linda Rydén, Ulrik Sartipy, Martin Holzmann
An acute worsening of renal function, so called acute kidney injury, is common in patients admitted to hospital. Acute kidney injury is associated with an increased long-term risk for chronic kidney disease, myocardial infarction, heart failure, and death. In order to prevent further deterioration of kidney function early identification of causes for acute kindey injury is of utmost importance. In most cases, there is no specific treatment of acute kidney injury, but several general principles should be followed: to strive for normovolemia, optimize hemodynamics, treat electrolyte disturbances, discontinue nephrotoxic agents, and to adjust dosages of medications which are renally eliminated...
May 3, 2016: Läkartidningen
C S C Bouman
OBJECTIVE: To summarize the general guidelines for drug dosing in critically-ill patients with acute kidney injury and continuous venovenous haemofiltration (CVVH), and to discuss whether the predicted dose adjustment is an as reliable estimate than one based on observed data, considering the recent literature. METHODS: Literature search was done in PubMed database for human studies. CONCLUSIONS: In critically-ill patients receiving CVVH, dosing of antibiotics based on the predicted clearances yield rough estimates...
2007: Acta Clinica Belgica
D Frei, J Briner, U Binswanger
The reported case of 2 brothers suffering from medullary sponge kindeys is unique in that uremia developed in spite of the absence of urinary tract obstruction, infection or hypertension. With the exception of congenital nystagmus and psoriasis, none of the extrarenal malformations often associated with medullary sponge kidneys was observed.
September 22, 1979: Schweizerische Medizinische Wochenschrift
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