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https://www.readbyqxmd.com/read/28813158/continuous-flow-synthesis-of-morpholines-and-oxazepanes-with-silicon-amine-protocol-slap-reagents-and-lewis-acid-facilitated-photoredox-catalysis
#1
Moritz K Jackl, Luca Legnani, Bill Morandi, Jeffrey W Bode
Photocatalytic coupling of aldehydes and silicon amine protocol (SLAP) reagents enables the simple, scalable synthesis of substituted morpholines, oxazepanes, thiomorpholines, and thiazepanes under continuous flow conditions. Key to the success of this process is the combination of an inexpensive organic photocatalyst (TPP) and a Lewis acid additive, which form an amine radical cation that is easily reduced to complete the catalytic cycle. Di- and trisubstituted SLAP reagents are formed in one step by an iron-catalyzed aminoetherification of olefins...
August 16, 2017: Organic Letters
https://www.readbyqxmd.com/read/28794582/what-are-the-anatomical-predictive-factors-of-degenerative-superior-labrum-anterior-to-posterior-lesion-in-rotator-cuff-tear
#2
Joong-Bae Seo, Jae-Sung Yoo, Joon-Yeul Lee, Kyoo-Hong Han
The purpose of this study was to evaluate the influence of anatomical factors degenerative superior labrum anterior to posterior lesion in rotator cuff tear. The study included 421 middle-aged patients treated using arthroscopic surgery for rotator cuff tears. Patients were divided into two groups based on the superior labrum anterior-to-posterior (SLAP). Glenoid inclination, glenoid length, humeral head diameter, acromio-humeral distance (AHD) head-glenoid difference (HGD), head glenoid angle (HGA), size and retraction of rotator cuff tears were evaluated in both groups...
December 2017: Journal of Orthopaedics
https://www.readbyqxmd.com/read/28777213/glenohumeral-instability-related-to-special-conditions-slap-tears-pan-labral-tears-and-multidirectional-instability
#3
Gregory S Van Blarcum, Steven J Svoboda
Glenohumeral instability is one of the more common conditions seen by sports medicine physicians, especially in young, active athletes. The associated anatomy of the glenohumeral joint (the shallow nature of the glenoid and the increased motion it allows) make the shoulder more prone to instability events as compared with other joints. Although traumatic dislocations or instability events associated with acute labral tears (ie, Bankart lesions) are well described in the literature, there exists other special shoulder conditions that are also associated with shoulder instability: superior labrum anterior/posterior (SLAP) tears, pan-labral tears, and multidirectional instability...
September 2017: Sports Medicine and Arthroscopy Review
https://www.readbyqxmd.com/read/28768619/lessons-to-be-learnt-from-the-study-sham-surgery-versus-labral-repair-or-biceps-tenodesis-for-type-ii-slap-lesions-of-the-shoulder-a-three-armed-randomised-clinical-trial
#4
EDITORIAL
Ann M Cools, Dorien Borms
No abstract text is available yet for this article.
August 2, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28763786/child-maltreatment-in-nepal-prevalence-and-associated-factors
#5
P Kandel, R Kunwar, S Karki, D Kandel, P Lamichhane
OBJECTIVES: Child maltreatment is a global public health problem. There is limited information about this problem in low-income countries. We aimed to document the prevalence and factors associated with physical punishment of children less than 14 years of age in Nepal. STUDY DESIGN: Population-based cross-sectional study. METHODS: We conducted an in-depth analysis using data from the Nepal Multiple Indicator Cluster Survey, a nationally representative multi-stage-stratified cluster sampling survey...
July 29, 2017: Public Health
https://www.readbyqxmd.com/read/28749175/direct-shoulder-magnetic-resonance-arthrography-for-superior-labral-anterior-to-posterior-slap-and-bankart-lesions-investigation-into-the-appropriate-dose-and-level-of-local-anesthesia
#6
Sun Hwa Lee, Seong Jong Yun, Hyeon Hwan Jo, Dong Hyeon Kim, Jae Gwang Song, Yong Sung Park
OBJECTIVES: To compare contrast leakage, pain score, image quality, and diagnostic performance at different doses and levels of local anesthesia for direct shoulder magnetic resonance arthrography (MRA). METHODS: Patients (n=157) were prospectively enrolled and allocated to group 1 (no local anesthetic), group 2 (local anesthesia to subcutaneous fat level; lidocaine 1-2 mL), group 3 (to deltoid muscle level; 3-5 mL), or group 4 (to subscapularis muscle level; 6-8 mL)...
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28745258/-a-fact-free-medicine-report-by-dutch-council-for-public-health-and-society-is-slap-in-the-face
#7
P M M Bossuyt
A recently released report by the Dutch Council for Public Health and Society ('Raad voor Volksgezondheid en Samenleving') is subtitled "About the illusion of evidence-based practice in healthcare". The author argues that this report is a sign of the times, a period of "post-truth medicine" and "alternative facts", in which "science offers nothing but a reduction". Although the report rightly - but superfluously - argues that having an evidence base is insufficient for delivering quality care (no decisions without considering context), its depiction of the illusory nature of evidence-based practice represents a brutal slap in the face of all those who turn to sound clinical and biomedical research to back up or refute claims about the effectiveness of healthcare interventions...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28713337/the-s-layer-associated-serine-protease-homolog-prtx-impacts-cell-surface-mediated-microbe-host-interactions-of-lactobacillus-acidophilus-ncfm
#8
Brant R Johnson, Sarah O'Flaherty, Yong Jun Goh, Ian Carroll, Rodolphe Barrangou, Todd R Klaenhammer
Health-promoting aspects attributed to probiotic microorganisms, including adhesion to intestinal epithelia and modulation of the host mucosal immune system, are mediated by proteins found on the bacterial cell surface. Notably, certain probiotic and commensal bacteria contain a surface (S-) layer as the outermost stratum of the cell wall. S-layers are non-covalently bound semi-porous, crystalline arrays of self-assembling, proteinaceous subunits called S-layer proteins (SLPs). Recent evidence has shown that multiple proteins are non-covalently co-localized within the S-layer, designated S-layer associated proteins (SLAPs)...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28696789/arthroscopic-knot-removal-for-failed-superior-labrum-anterior-posterior-repair-secondary-to-knot-induced-pain
#9
Jung Gwan Park, Nam Su Cho, Jung Youn Kim, Jong Hoon Song, Se Jung Hong, Yong Girl Rhee
BACKGROUND: Studies on failed superior labrum anterior-posterior (SLAP) repair are increasing. However, the number of reports on treatment options for failed SLAP repair remains quite low, and the clinical results vary between different study groups. PURPOSE: To describe the clinical presentation of failed SLAP repair due to knot-induced pain and evaluate the efficacy of arthroscopic knot removal. STUDY DESIGN: Case series; Level of evidence, 4...
July 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28677337/the-multiple-functions-of-male-song-within-the-humpback-whale-megaptera-novaeangliae-mating-system-review-evaluation-and-synthesis
#10
Louis M Herman
Humpback whales (Megaptera novaeangliae) are seasonal breeders, annually migrating from high-latitude summer feeding grounds to low-latitude winter breeding grounds. The social matrix on the winter grounds is a loose network of interacting individuals and groups and notably includes lone males that produce long bouts of complex song that collectively yield an asynchronous chorus. Occasionally, a male will sing while accompanying other whales. Despite a wealth of knowledge about the social matrix, the full characterization of the mating system remains unresolved, without any firm consensus, as does the function of song within that system...
August 2017: Biological Reviews of the Cambridge Philosophical Society
https://www.readbyqxmd.com/read/28676051/community-perceptions-on-outdoor-malaria-transmission-in-kilombero-valley-southern-tanzania
#11
Irene R Moshi, Halfan Ngowo, Angel Dillip, Daniel Msellemu, Edith P Madumla, Fredros O Okumu, Maureen Coetzee, Ladslaus L Mnyone, Lenore Manderson
BACKGROUND: The extensive use of indoor residual spraying (IRS) and insecticide-treated nets (ITNs) in Africa has contributed to a significant reduction in malaria transmission. Even so, residual malaria transmission persists in many regions, partly driven by mosquitoes that bite people outdoors. In areas where Anopheles gambiae s.s. is a dominant vector, most interventions target the reduction of indoor transmission. The increased use of ITNs/LLINs and IRS has led to the decline of this species...
July 4, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28675978/concomitant-slap-repair-does-not-influence-the-surgical-outcome-for-arthroscopic-bankart-repair-of-traumatic-shoulder-dislocations
#12
Nuri Aydin, Mehmet Bekir Unal, Mustafa Asansu, Okan Tok
BACKGROUND: Prior studies revealed the presence of superior labrum anterior-to-posterior (SLAP) injury together with Bankart lesions in some patients. The purpose of the study is to compare the clinical results of isolated Bankart repairs with the clinical results of Bankart repairs when performed with concomitant SLAP repairs. METHODS: The patients who underwent arthroscopic surgery for treatment of anterior glenohumeral instability were evaluated retrospectively...
May 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28610563/progression-of-function-and-pain-relief-as-indicators-for-returning-to-sports-after-arthroscopic-isolated-type-ii-slap-repair-a-prospective-study
#13
Sandra Boesmueller, Thomas M Tiefenboeck, Marcus Hofbauer, Adam Bukaty, Gerhard Oberleitner, Wolfgang Huf, Christian Fialka
BACKGROUND: One of the currently used surgical techniques in isolated type II SLAP lesions is arthroscopic SLAP repair. Postoperatively, patients tend to suffer from a prolonged period of pain and are restricted in their sports activities for at least 6 months. The aim of this study was to prospectively evaluate the clinical outcome as well as the postoperative course of pain after arthroscopic type II SLAP repair. METHODS: Outcome measures were assessed using the Individual Relative Constant Score (CSindiv), the American Shoulder and Elbow Surgeons (ASES) Score, the Visual Analogue Scale (VAS), and the Short Form 36 (SF-36)...
June 13, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28604236/diagnosis-of-superior-labrum-anterior-to-posterior-tears-by-using-mr-imaging-and-mr-arthrography-a-systematic-review-and-meta-analysis
#14
John S Symanski, Naveen Subhas, James Babb, Joseph Nicholson, Soterios Gyftopoulos
Purpose To evaluate the diagnostic accuracies of nonenhanced magnetic resonance (MR) imaging and MR arthrography for diagnosis of superior labrum anterior-to-posterior (SLAP) tears by using a systematic review and meta-analysis. Materials and Methods A comprehensive literature search was performed on the two main concepts of MR imaging (MR imaging, and direct and indirect MR arthrography) and SLAP tears. Inclusion criteria consisted of original studies that assessed the diagnostic accuracy of MR imaging, direct MR arthrography, and/or indirect MR arthrography for the detection of SLAP tears, by using surgical findings as the reference standard...
June 12, 2017: Radiology
https://www.readbyqxmd.com/read/28594489/diagnosis-and-management-of-the-biceps-labral-complex
#15
Robert J Thorsness, Anthony A Romeo
The long head of the biceps tendon (LHBT) is a common source of pathology. The biceps-labral complex (BLC) is the collective anatomic and clinical features shared by the biceps tendon and the superior labrum. LHBT pathology can be caused by inflammation, instability, or trauma. Numerous tests can be performed to determine the existence of biceps tendon and superior labrum anterior to posterior (SLAP) lesions; however, many of these tests do not have high sensitivity and specificity, which limit their clinical utility...
February 15, 2017: Instructional Course Lectures
https://www.readbyqxmd.com/read/28555366/pulley-lesions-in-rotator-cuff-tears-prevalence-etiology-and-concomitant-pathologies
#16
Nael Hawi, Emmanouil Liodakis, Christina Garving, Peter Habermeyer, Mark Tauber
PURPOSE: This study aimed to demonstrate the prevalence of lesions in the biceps pulley complex in a representative, consecutive series of rotator cuff tears and rotator cuff interval treatments. We also analyzed associated tear pattern of rotator cuff injuries and superior labrum anterior-posterior (SLAP) lesions. We evaluated the relationships of these lesions to traumatic genesis and the prevalence of pulley lesions in revision cases. METHODS: This retrospective study analyzed all pre- and intra-operative documentation on arthroscopic rotator cuff reconstructions and isolated pulley lesion treatments performed by a single surgeon over 2 consecutive years...
May 29, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28535755/the-relationships-between-harsh-physical-punishment-and-child-maltreatment-in-childhood-and-intimate-partner-violence-in-adulthood
#17
Tracie O Afifi, Natalie Mota, Jitender Sareen, Harriet L MacMillan
BACKGROUND: Physical punishment of children is an important public health concern. Yet, few studies have examined how physical punishment is related to other types of child maltreatment and violence across the lifespan. Therefore, the objective of the current study was to examine if harsh physical punishment (i.e., being pushed, grabbed, shoved, hit, and/or slapped without causing marks, bruises, or injury) is associated with an increased likelihood of more severe childhood maltreatment (i...
May 23, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28509865/detecting-and-classifying-human-touches-in-a-social-robot-through-acoustic-sensing-and-machine-learning
#18
Fernando Alonso-Martín, Juan José Gamboa-Montero, José Carlos Castillo, Álvaro Castro-González, Miguel Ángel Salichs
An important aspect in Human-Robot Interaction is responding to different kinds of touch stimuli. To date, several technologies have been explored to determine how a touch is perceived by a social robot, usually placing a large number of sensors throughout the robot's shell. In this work, we introduce a novel approach, where the audio acquired from contact microphones located in the robot's shell is processed using machine learning techniques to distinguish between different types of touches. The system is able to determine when the robot is touched (touch detection), and to ascertain the kind of touch performed among a set of possibilities: stroke, tap, slap, and tickle (touch classification)...
May 16, 2017: Sensors
https://www.readbyqxmd.com/read/28495804/sham-surgery-versus-labral-repair-or-biceps-tenodesis-for-type-ii-slap-lesions-of-the-shoulder-a-three-armed-randomised-clinical-trial
#19
Cecilie Piene Schrøder, Øystein Skare, Olav Reikerås, Petter Mowinckel, Jens Ivar Brox
BACKGROUND: Labral repair and biceps tenodesis are routine operations for superior labrum anterior posterior (SLAP) lesion of the shoulder, but evidence of their efficacy is lacking. We evaluated the effect of labral repair, biceps tenodesis and sham surgery on SLAP lesions. METHODS: A double-blind, sham-controlled trial was conducted with 118 surgical candidates (mean age 40 years), with patient history, clinical symptoms and MRI arthrography indicating an isolated type II SLAP lesion...
May 11, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28451607/outcomes-after-arthroscopic-bankart-repair-in-adolescent-athletes-participating-in-collision-and-contact-sports
#20
Michael G Saper, Charles Milchteim, Robert L Zondervan, James R Andrews, Roger V Ostrander
BACKGROUND: Literature on arthroscopic stabilization in adolescent patients participating in collision and contact sports is limited, as most studies include adolescents within a larger sample group comprised primarily of adults. PURPOSE: To review the outcomes of arthroscopic Bankart repair for anterior shoulder instability in an adolescent population participating in collision and contact sports. STUDY DESIGN: Case series; Level of evidence, 4...
March 2017: Orthopaedic Journal of Sports Medicine
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