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https://www.readbyqxmd.com/read/28922391/impedance-biosensor-for-real-time-monitoring-and-prediction-of-thrombotic-individual-profile-in-flowing-blood
#1
Denise De Zanet, Monica Battiston, Elisabetta Lombardi, Ruben Specogna, Francesco Trevisan, Luigi De Marco, Antonio Affanni, Mario Mazzucato
A new biosensor for the real-time analysis of thrombus formation is reported. The fast and accurate monitoring of the individual thrombotic risk represents a challenge in cardiovascular diagnostics and in treatment of hemostatic diseases. Thrombus volume, as representative index of the related thrombotic status, is usually estimated with confocal microscope at the end of each in vitro experiment, without providing a useful behavioral information of the biological sample such as platelets adhesion and aggregation in flowing blood...
2017: PloS One
https://www.readbyqxmd.com/read/28920416/effects-of-aflatoxin-b1-combined-with-ochratoxin-a-and-or-zearalenone-on-metabolism-immune-function-and-antioxidant-status-in-lactating-dairy-goats
#2
Shuai Huang, Nan Zheng, CaiYun Fan, Ming Cheng, Shang Wang, Adil Jabar, JiaQi Wang, JianBo Cheng
Objective: This experiment was conducted to investigate the effects of aflatoxin B1 (AFB1) alone or mixed with ochratoxin A (OTA) and/or zearalenone (ZEA) on the metabolism, immune function, and antioxidant status of dairy goats. Methods: Fifty lactating Laoshan dairy goats were randomly assigned to one of five treatment groups (n = 10) for 14 days. Goats were fed no additive (control) or administered with 50 μg AFB1/kg DM (AFB1), 50 μg AFB1/kg DM + 100 μg OTA/kg DM (AFB1+OTA), 50 μg AFB1/kg DM + 500 μg ZEA/kg DM (AFB1+ZEA), or 50 μg AFB1/kg DM + 100 μg OTA/kg DM + 500 μg ZEA/kg DM (AFB1+OTA+ZEA)...
September 18, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28919829/age-and-sex-related-changes-in-hematological-parameters-in-healthy-malawians
#3
Wilson L Mandala, Esther N Gondwe, Jenny M MacLennan, Malcolm E Molyneux, Calman A MacLennan
AIM: The aim of the study was to determine how values for white blood cell (WBC) counts, hemoglobin (Hb), hematocrit (Hct), mean corpuscular volume (mcv), and platelet counts vary with age and sex in healthy Malawians. METHODS: We recruited 660 (316 male and 344 female) participants in 12 different age groups. An ethylenediaminetetraacetic acid-anticoagulated blood sample collected from each participant was analyzed using a hematological analyzer. RESULTS: WBC counts decreased with age with the lowest counts observed in the 20 to <60 years old group...
2017: Journal of Blood Medicine
https://www.readbyqxmd.com/read/28919711/protective-role-of-quercetin-against-manganese-induced-injury-in-the-liver-kidney-and-lung-and-hematological-parameters-in-acute-and-subchronic-rat-models
#4
Entaz Bahar, Geum-Hwa Lee, Kashi Raj Bhattarai, Hwa-Young Lee, Hyun-Kyoung Kim, Mallikarjun Handigund, Min-Kyung Choi, Sun-Young Han, Han-Jung Chae, Hyonok Yoon
Manganese (Mn) is an important mineral element required in trace amounts for development of the human body, while over- or chronic-exposure can cause serious organ toxicity. The current study was designed to evaluate the protective role of quercetin (Qct) against Mn-induced toxicity in the liver, kidney, lung, and hematological parameters in acute and subchronic rat models. Male Sprague Dawley rats were divided into control, Mn (100 mg/kg for acute model and 15 mg/kg for subchronic model), and Mn + Qct (25 and 50 mg/kg) groups in both acute and subchronic models...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28918942/withdrawn-relation-of-mean-platelet-volume-to-lymphocyte-ratio-and-contrast-induced-acute-kidney-injury-in-patients-with-acute-coronary-syndrome-undergoing-percutaneous-coronary-intervention
#5
Alparslan Kurtul, Selcuk Ozturk
This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal.
August 8, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28912725/enhanced-strength-and-sprint-levels-and-changes-in-blood-parameters-during-a-complete-athletics-season-in-800-m-high-level-athletes
#6
Beatriz Bachero-Mena, Fernando Pareja-Blanco, Juan J González-Badillo
The purpose of this study was to analyze changes in sprint, strength, hematological, and hormonal parameters in high-level 800 m athletes during a complete athletics season. Thirteen male athletes of national and international level in 800 m (personal best ranging from 1:43 to 1:58 min:ss) participated in this study. A total of 5 tests were conducted during a complete athletics season. Athletes performed sprint tests (20 and 200 m), countermovement jump (CMJ), jump squat (JS), and full squat (SQ) tests. Blood samples (red and white blood profile) and hormones were collected in test 1 (T1), test 3 (T3), and test 5 (T5)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28904970/responders-to-platelet-rich-plasma-in-osteoarthritis-a-technical-analysis
#7
REVIEW
Christophe Milants, Olivier Bruyère, Jean-François Kaux
PURPOSE: To evaluate the similarities and differences between the variety of platelet-rich plasma (PRP) formulations, preparation, and uses to try to determine the best responses for the treatment of knee osteoarthritis. MATERIALS AND METHODS: A comparison of the outcomes of randomized controlled trials (RCTs) included in the 3 most recent and high-quality meta-analyses to classify the different studies in 2 groups (bad responders group (BRG) and very good responders group (VGRG))...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28902040/long-term-rifaximin-therapy-as-a-primary-prevention-of-hepatorenal-syndrome
#8
El-Sayed Ibrahim, Ayman Alsebaey, Hassan Zaghla, Sabry Moawad Abdelmageed, Khalid Gameel, Eman Abdelsameea
BACKGROUND: Hepatorenal syndrome (HRS) is a severe complication of liver cirrhosis, with poor survival. Rifaximin is a gut-selective broad-spectrum antibiotic. AIM: The aim of this study was to evaluate the role of rifaximin as a primary prevention of HRS. PATIENTS AND METHODS: Eighty patients with liver cirrhosis and ascites were enrolled. They were randomized into two groups: control (n=40) and rifaximin group (n=40). Baseline liver function tests, renal function tests, complete blood count, international normalized ratio, urine analysis, and abdominal ultrasonography were carried out...
September 8, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28892906/changes-in-haematological-parameters-in-newborns-born-to-preeclamptic-mothers-a-case-control-study-in-a-rural-hospital
#9
Kalavakuru Mouna, Shilpa Manigatta Doddagowda, Krishnappa Junjegowda, Latha Krishnamurthy
INTRODUCTION: Pregnancy is a physiological phenomenon. However, some women develop problems during pregnancy period, which puts both the mother's and the foetus health at risk. Hypertensive disorders of pregnancy are the type of the maternal diseases that can cause the most detrimental effects to the mother and foetus. AIMS: To determine the haematological parameters in neonates born to preeclamptic mothers. MATERIALS AND METHODS: It was a prospective case control study carried out on neonates born to preeclamptic mothers in our institute from March 2016 to November 2016...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28885341/differences-in-platelet-related-parameters-among-patients-with-audiographically-distinct-sudden-sensorineural-hearing-loss-a-retrospective-study
#10
Yuanyuan Sun, Yang Guo, Hui Wang, Zhengnong Chen, Yaqin Wu, Haibo Shi, Yanmei Feng, Shankai Yin
We explored possible relationships between sudden sensorineural hearing loss (SSNHL) in patients differing in terms of audiographic data and the levels of vascular markers in routine blood data.We included 37 patients with low-frequency SSNHL (LF-SSNHL), 28 with high-frequency SSNHL (HF-SSNHL), 32 with all-frequency SSNHL (AF-SSNHL), 32 with total-deafness SSNHL (TD-SSNHL), and 31 age- and sex-matched healthy controls. Peripheral venous blood samples were collected, and routine blood parameters including platelet and lymphocyte count, mean platelet volume (MPV), and platelet-to-lymphocyte ratio (PLR) were measured...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28884559/artificial-neural-network-predicts-hemorrhagic-contusions-following-decompressive-craniotomy-in-traumatic-brain-injury
#11
Jian-Li Wang, Guo-Liang Jin, Zi-Gang Yuan
OBJECTIVE: This study aimed to explore relevant factors of hemorrhagic contusions following decompressive craniotomy (DC) in traumatic brain injury (TBI), and create an artificial neural network (ANN) prediction model of the risk factors of hemorrhagic contusions. METHODS: This study analyzed 425 patients with TBI who underwent DC in the Neurosurgery Department of Shaoxing People's Hospital between 2009 and 2014. Patients were divided into two groups according to the first postoperative CT scans: hemorrhage group and non-hemorrhage group...
September 7, 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28884390/patients-treated-for-acute-vte-during-periods-of-treatment-related-thrombocytopenia-have-high-rates-of-recurrent-thrombosis-and-transfusion-related-adverse-outcomes
#12
B T Samuelson Bannow, R B Walter, T B Gernsheimer, D A Garcia
Venous thromboembolism (VTE) is a common complication of hematologic malignancies. Prolonged periods of thrombocytopenia are experienced universally by patients undergoing treatment for these diseases, yet data to guide management of anticoagulation in this setting are lacking. To obtain data on the management and outcomes of VTE in patients with thrombocytopenia related to the treatment of hematologic malignancies. This was an observational cohort study of patients experiencing VTE during periods of treatment-related thrombocytopenia over a 5-year period at the Fred Hutchinson Cancer Research Center...
September 7, 2017: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/28883472/the-relationship-between-hematological-indices-and-autoimmune-rheumatic-diseases-ards-a-meta-analysis
#13
Xuanyu Hao, Dongyang Li, Dan Wu, Ning Zhang
This meta-analysis was undertaken to investigate the relationship between hematological indices and autoimmune rheumatic diseases (ARDs). PubMed, Embase, and Web of Science were searchedfor studies of ARDs and hematological indices. Standardized mean difference (SMD) was calculated with confidence interval (CI) of 95%. 18 studies were included in our meta-analysis. Compared to the healthy control group, neutrophil-lymphocyte ratio (NLR) was increased in patients with ankylosing spongdylitis(AS), Behçet's disease(BD), andrheumatoid arthritis(RA)(SMD = 0...
September 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28879723/mean-platelet-volume-and-platelet-count-are-elevated-in-patients-with-subacute-thyroiditis
#14
Zhe Fan, Shunxiong Tang
BACKGROUND: Platelet parameters have been studied in many diseases. This study explored the changes of mean platelet volume (MPV) and platelet count (PLT) in subacute thyroiditis (SAT). METHODS: We retrospectively studied 44 patients with SAT and 45 healthy individuals. Diagnosis was confirmed by pathologic examination of surgical specimens. RESULTS: There were no significant differences in age and gender between the SAT group and the control group...
September 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/28874620/diagnostic-value-of-platelet-indices-in-acute-appendicitis-and-comparison-with-histopathology
#15
Mehmet Emin Gu Nes, Mehmet Mehdi Deniz, Serhan Yılmaz
BACKGROUND: Acute appendicitis is one of the most common surgical emergencies. An early and accurate diagnosis of acute appendicitis is vital. Evidence for a link between platelets indices and inflammation disease comes from recent studies. We aimed to evaluate preoperative diagnostic values of platelet indices (Mean platelet volume-MPV, Platelet Distribution Width-PDW, Plateletcrit-PCT) and leukocyte count (WBC) in comparison with post-operative histopathology results in patients who underwent appendectomy...
2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28872644/self-assembly-behaviour-of-hetero-nuclear-janus-dumbbells
#16
Patrick O'Toole, Gianmarco Munaò, Achille Giacometti, Toby S Hudson
We investigate the fluid structure and self-assembly of a system of Janus dumbbells by means of aggregation-volume-bias Monte Carlo simulations and Simulated Annealing techniques. In our approach, Janus dumbbells model asymmetric colloidal particles constituted by two tangent (touching) spheres (labelled as h and s) of different sizes and interaction properties: specifically, the h spheres interact with all other spheres belonging to different dumbbells via hard-sphere potentials, whereas two s spheres interact via a square-well potential...
September 5, 2017: Soft Matter
https://www.readbyqxmd.com/read/28872499/mean-platelet-volume-red-cell-distribution-width-and-neutrophil-to-lymphocyte-ratio-before-and-after-surgery-in-patients-with-carotid-body-tumors
#17
Nazim Bozan, Ömer Faruk Kocak, Mehmet Emre Dinc, Canser Yilmaz Demir, Mahfuz Turan, Ahmet Faruk Kiroglu
OBJECTIVE: Carotid body tumors (CBTs) are rare hypervascular benign tumors that originate from the paraganglia at the carotid bifurcation. The red cell distribution width (RDW), neutrophil-to-lymphocyte ratio (NLR), and mean platelet volume (MPV) may serve as markers in inflammatory, cardiovascular, and neoplastic diseases. However, their prognostic value in CBTs is unknown. The purpose of this study was to assess the leukocyte count, MPV, RDW, and NLR before and after surgery in patients with CBTs...
September 1, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28872144/volume-segmentation-and-analysis-of-biological-materials-using-survos-super-region-volume-segmentation-workbench
#18
Michele C Darrow, Imanol Luengo, Mark Basham, Matthew C Spink, Sarah Irvine, Andrew P French, Alun W Ashton, Elizabeth M H Duke
Segmentation is the process of isolating specific regions or objects within an imaged volume, so that further study can be undertaken on these areas of interest. When considering the analysis of complex biological systems, the segmentation of three-dimensional image data is a time consuming and labor intensive step. With the increased availability of many imaging modalities and with automated data collection schemes, this poses an increased challenge for the modern experimental biologist to move from data to knowledge...
August 23, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28869150/the-association-between-hematological-parameters-and-metabolic-syndrome-in-iranian-men-a-single-center-large-scale-study
#19
Jamal Ahmadzadeh, Behnam Mansorian, Mohammad Mirza-Aghazadeh Attari, Ira Mohebbi, Raha Naz-Avar, Karaim Moghadam, Seyyed Adel Khoshbou Ghareh-Bagh
AIMS: Some studies have demonstrated that metabolic syndrome is associated with hematological parameters. The present study explores the relationship between hematological parameters and numbers of metabolic syndrome conditions in Iranian men. METHODS: This cross-sectional study included 11,114 participants who were professional drivers of commercial motor vehicles, and were enrolled in the Iranian Health Surveys between 2014 and 2016. Diagnosis of metabolic syndrome was made according to International Diabetes Federation criteria...
August 23, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28865245/the-sh2b3-and-kcnk5-loci-may-be-implicated-in-regulation-of-platelet-count-volume-and-maturity
#20
Morten K Christiansen, Sanne B Larsen, Mette Nyegaard, Søs Neergaard-Petersen, Morten Würtz, Erik L Grove, Anne-Mette Hvas, Henrik K Jensen, Steen D Kristensen
INTRODUCTION: In recent genome-wide association studies, coronary artery disease (CAD) and myocardial infarction (MI) have been linked to a number of genetic variants, but their role in thrombopoiesis is largely unknown. AIM: We investigated the association between CAD and MI-associated genetic variants and five thrombopoiesis-related indices: platelet count (PC), mean platelet volume (MPV), immature platelet count (IPC), immature platelet fraction (IPF), and serum thrombopoietin (TPO)...
August 18, 2017: Thrombosis Research
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