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https://www.readbyqxmd.com/read/28346659/is-universal-hla-b-15-02-screening-a-cost-effective-option-in-an-ethnically-diverse-population-a-case-study-of-malaysia
#1
H Y Chong, Z Mohamed, L L Tan, D B C Wu, F H Shabaruddin, M Dahlui, Y D Apalasamy, S R Snyder, M S Williams, J Hao, L H Cavallari, N Chaiyakunapruk
BACKGROUND: Strong association was documented between human leukocyte antigen (HLA)-B*15:02 and carbamazepine-induced severe cutaneous adverse reactions (SCARs) in Asians. Beyond Asia, the HLA testing is potentially valuable in many countries with increasingly diverse communities of Asian ancestry, to facilitate an early recognition of patient susceptibility to SCARs. OBJECTIVE: To determine the cost-effectiveness of universal HLA-B*15:02 screening in preventing carbamazepine-induced Stevens-Johnson syndrome/ toxic epidermal necrolysis in an ethnically-diverse Malaysian population...
March 27, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28346633/one-stage-posterior-approach-in-the-treatment-of-consecutive-multi-segment-thoracic-tuberculosis-with-kyphosis
#2
Zhong Nanzhe, Kong Jinhai, Sun Zhengwang, Qian Ming, Liu Tielong, Xiao Jianru
AIM: This study is to evaluate the clinical efficacy of one-stage posterior approach in treating consecutive multiple-segment thoracic tuberculosis with kyphosis. MATERIAL AND METHODS: A retrospective study was performed. The data of 22 patients with consecutive multi-level thoracic tuberculosis who underwent one-stage posterior approach of debridement, bone grafting, and drainage with pedicle screws fixation were collected. The kyphotic angle was 61.6°±3.1° pre-operatively...
February 27, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28346562/joint-association-of-obesity-and-hypertension-with-disability-in-the-elderly-a-community-based-study-of-residents-in-shanghai-china
#3
P Su, H Ding, W Zhang, G Duan, Y Yang, J Long, L Du, C Xie, C Jin, C Hu, Z Sun, Z Duan, L Gong, W Tian
BACKGROUND: Although both obesity and hypertension are known risk factors for disability, the joint association of obesity and hypertension with risk of disability is unknown. This paper is aim to examine the joint association of obesity and hypertension with risk of disability. METHODS: Cross-sectional study with 8060 elderly community-dwelling individuals participating in the survey initiated by Shanghai Health and Family Planning Commission from March to September 2013...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28346031/chromogranin-a-cell-density-in-the-large-intestine-of-asian-and-european-patients-with-irritable-bowel-syndrome
#4
Magdy El-Salhy, Tanisa Patcharatrakul, Jan Gunnar Hatlebakk, Trygve Hausken, Odd Helge Gilja, Sutep Gonlachanvit
OBJECTIVE: Patients with irritable bowel syndrome (IBS) in Asia show distinctive differences from those in the western world. The gastrointestinal endocrine cells appear to play an important role in the pathophysiology of IBS. The present study aimed at studying the density of chromogranin A (CgA) cells in the large intestine of Thai and Norwegian IBS patients. METHODS: Thirty Thai IBS patients and 20 control subjects, and 47 Norwegian IBS patients and 20 control subjects were included...
March 27, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/28345890/relationship-of-microbiota-and-cyanobacterial-secondary-metabolites-in-planktothricoides-dominated-bloom
#5
Shu Harn Te, Boon Fei Tan, Janelle Renee Thompson, Karina Yew-Hoong Gin
Identification of phytoplankton species and microbial biodiversity is necessary to assess water ecosystem health and the quality of water resources. We investigated the short-term (2 days) vertical and diel variations in bacterial community structure and microbially-derived secondary metabolites during a cyanobacterial bloom that emerged in a highly urbanized tropical reservoir. The waterbody was largely dominated by the cyanobacteria Planktothricoides spp., together with the Synechococcus, Pseudanabaena, Prochlorothrix and Limnothrix...
March 27, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28345829/high-fluoroquinolone-resistant-strains-of-helicobacter-pylori-in-the-golden-triangle
#6
Ratha Korn Vilaichone, Thawee Ratanachu ek, Pornpen Gamnarai, Phawinee Subsomwong, Tomahisa Uchida, Yoshio Yamaoka, Varocha Mahachai
Background and aims: Helicobacter pylori (H. pylori) infections, associated with fatal GI diseases such as gastric cancer and MALT lymphoma, remain a major health problem in ASEAN countries. The Golden triangle has long been known as one of Asia’s main opium-producing areas. There have been no prior studies of H. pylori infection in this area. The major objectives of this project were therefore to establish prevalence, antibiotic resistance patterns and associated predictive in the Golden triangle. Methods: We recruited dyspeptic patients in Chiang khong and Chiang saen districts, Chiangrai province of Thailand...
February 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28345752/recent-field-experiments-with-commercial-satellite-imagery-direct-downlink
#7
Anthony R Gonzalez, Samuel H Amber
US Pacific Command's strategy includes assistance to United States government relief agencies and nongovernment organizations during humanitarian aid and disaster relief operations in the Asia-Pacific region. Situational awareness during these operations is enhanced by broad interagency access to unclassified commercial satellite imagery. The Remote Ground Terminal-a mobile satellite downlink ground station-has undergone several technology demonstrations and participated in an overseas deployment exercise focused on a natural disaster scenario...
January 2017: Journal of Emergency Management: JEM
https://www.readbyqxmd.com/read/28345563/chlamydial-eye-infections-current-perspectives
#8
Gita Satpathy, Himanshu Sekhar Behera, Nishat Hussain Ahmed
Chlamydia trachomatis, an obligate intraocular bacteria causing trachoma, adult and neonatal inclusion conjunctivitis, was the leading cause of blindness in the last century worldwide. Improvement in socioeconomic and living conditions, availability of antibiotics, and introduction of National Trachoma Control Programmes reduced the prevalence in developed countries, but it persisted in resource-poor settings of Africa and Asia, including India. In 2016, as per the WHO report, trachoma is restricted to 42 countries, causing blindness/visual impairment in ~1...
February 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28345507/plasmodium-knowlesi-invasion-following-spread-by-infected-mosquitoes-macaques-and-humans
#9
Laith Yakob, Alun L Lloyd, Rowland R Kao, Heather M Ferguson, Patrick M Brock, Chris Drakeley, Michael B Bonsall
Plasmodium knowlesi is increasingly recognized as a major cause of malaria in Southeast Asia. Anopheles leucosphyrous group mosquitoes transmit the parasite and natural hosts include long-tailed and pig-tailed macaques. Despite early laboratory experiments demonstrating successful passage of infection between humans, the true role that humans play in P. knowlesi epidemiology remains unclear. The threat posed by its introduction into immunologically naïve populations is unknown despite being a public health priority for this region...
March 27, 2017: Parasitology
https://www.readbyqxmd.com/read/28345200/all-roads-lead-to-weediness-patterns-of-genomic-divergence-reveal-extensive-recurrent-weedy-rice-origins-from-south-asian-oryza
#10
Zhongyun Huang, Nelson D Young, Michael Reagon, Katie E Hyma, Kenneth M Olsen, Yulin Jia, Ana L Caicedo
Weedy rice (Oryza spp.), a weedy relative of cultivated rice (O. sativa), infests and persists in cultivated rice fields worldwide. Many weedy rice populations have evolved similar adaptive traits, considered part of the "agricultural weed syndrome," making this an ideal model to study the genetic basis of parallel evolution. Understanding parallel evolution hinges on accurate knowledge of the genetic background and origins of existing weedy rice groups. Using population structure analyses of South Asian and US weedy rice, we show that weeds in South Asia have highly heterogeneous genetic backgrounds, with ancestry contributions both from cultivated varieties (aus and indica) and wild rice...
March 27, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28344929/comparing-regional-precipitation-and-temperature-extremes-in-climate-model-and-reanalysis-products
#11
Oliver Angélil, Sarah Perkins-Kirkpatrick, Lisa V Alexander, Dáithí Stone, Markus G Donat, Michael Wehner, Hideo Shiogama, Andrew Ciavarella, Nikolaos Christidis
A growing field of research aims to characterise the contribution of anthropogenic emissions to the likelihood of extreme weather and climate events. These analyses can be sensitive to the shapes of the tails of simulated distributions. If tails are found to be unrealistically short or long, the anthropogenic signal emerges more or less clearly, respectively, from the noise of possible weather. Here we compare the chance of daily land-surface precipitation and near-surface temperature extremes generated by three Atmospheric Global Climate Models typically used for event attribution, with distributions from six reanalysis products...
September 2016: Weather Clim Extrem
https://www.readbyqxmd.com/read/28344513/a-final-year-nursing-student-survey-rural-attitudes-perceived-competencies-and-intention-to-work-across-five-asian-countries
#12
Nareerut Pudpong, Rapeepong Suphanchaimat, Bipin Batra, Jianlin Hou, Lan T H Vu, Paul Dipika
BACKGROUND: Shortages and maldistribution of nurses remain significant problems in many countries. Having appropriate intervention strategies to retain nurses in underserved areas, where they are most needed, are crucial for health system strengthening. This study aimed to quantify attitudes to working in rural areas, perceived competencies, and intention to work among final-year nursing students, and to analyze the associations between those factors and their background characteristics across five countries in the Asia-Pacific Network for Health Professional Education Reforms (ANHER), namely Bangladesh, China, India, Thailand, and Vietnam...
2017: BMC Nursing
https://www.readbyqxmd.com/read/28344127/replicated-association-between-the-european-gwas-locus-rs10503253-at-csmd1-and-schizophrenia-in-asian-population
#13
Weiqing Liu, Fang Liu, Xiufeng Xu, Yan Bai
Schizophrenia is one of the most severe mental disorders with significant heritability. Recent genetic association studies including genome-wide association studies (GWAS) have identified multiple common variants conferring risk of schizophrenia. An intronic SNP within CSMD1, rs10503253, is one of the top risk SNPs for schizophrenia in Europeans discovered through large GWAS. However, whether rs10503253 is also a risk SNP for schizophrenia in other populations, such as Asians, is still unknown. To answer this question, we examined the association of rs10503253 with schizophrenia in a total of 7,514 schizophrenia patients, 9,058 healthy controls and 1,115 nuclear families originated from Asia using a meta-analytic approach...
March 23, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28344107/molecular-phylogenetics-and-historical-biogeography-of-sorbus-sensu-stricto-rosaceae
#14
Meng Li, Ohi-Toma Tetsuo, Yun-Dong Gao, Bo Xu, Zhang-Ming Zhu, Wen-Bin Ju, Xin-Fen Gao
Explaining how plants from eastern Asia migrated to other Northern Hemisphere regions is still challenging. The genus Sorbus sensu stricto (including c. 88 species) is considered as a good example to illuminate this scenario, due to the wide distribution in the temperate zone and high diversity in the Himalayas and Hengduan Mountains. Based on four nuclear markers (LEAFY-2, GBSSI-1, SBEI and WD) and one chloroplast marker (rps16-trnK), we reconstructed the phylogenetic relationship of Sorbus using 54 taxa (60% of the genus representing all subgenera, sections, or series and geographical areas in the previous classifications), and estimated divergence time and historical biogeography of the genus...
March 23, 2017: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/28344011/the-epidemiology-pathogenesis-transmission-diagnosis-and-management-of-multidrug-resistant-extensively-drug-resistant-and-incurable-tuberculosis
#15
REVIEW
Keertan Dheda, Tawanda Gumbo, Gary Maartens, Kelly E Dooley, Ruth McNerney, Megan Murray, Jennifer Furin, Edward A Nardell, Leslie London, Erica Lessem, Grant Theron, Paul van Helden, Stefan Niemann, Matthias Merker, David Dowdy, Annelies Van Rie, Gilman K H Siu, Jotam G Pasipanodya, Camilla Rodrigues, Taane G Clark, Frik A Sirgel, Aliasgar Esmail, Hsien-Ho Lin, Sachin R Atre, H Simon Schaaf, Kwok Chiu Chang, Christoph Lange, Payam Nahid, Zarir F Udwadia, C Robert Horsburgh, Gavin J Churchyard, Dick Menzies, Anneke C Hesseling, Eric Nuermberger, Helen McIlleron, Kevin P Fennelly, Eric Goemaere, Ernesto Jaramillo, Marcus Low, Carolina Morán Jara, Nesri Padayatchi, Robin M Warren
Global tuberculosis incidence has declined marginally over the past decade, and tuberculosis remains out of control in several parts of the world including Africa and Asia. Although tuberculosis control has been effective in some regions of the world, these gains are threatened by the increasing burden of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis. XDR tuberculosis has evolved in several tuberculosis-endemic countries to drug-incurable or programmatically incurable tuberculosis (totally drug-resistant tuberculosis)...
March 15, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28343779/antigenic-and-immunogenic-spectrum-of-foot-and-mouth-disease-vaccine-strain-o1-campos-against-representative-viruses-of-topotypes-that-circulated-in-asia-over-the-past-decade
#16
S Galdo Novo, V Malirat, E D Maradei, A M Espinoza, E Smitsaart, A R Pedemonte, N Mattion, I E Bergmann
Identifying vaccine strains to control outbreaks of foot-and-mouth disease virus that could spread to new regions is essential for contingency plans. This is the first report on the antigenic/immunogenic relationships of the South American O1/Campos vaccine strain with representative isolates of the three currently active Asian type O topotypes. Virus neutralization tests using O1/Campos post-vaccination sera derived from cattle and pigs predicted for both species acceptable cross-protection, even after single vaccination, established by r1 values and by expectancy of protection using monovalent or polyvalent vaccines...
March 23, 2017: Vaccine
https://www.readbyqxmd.com/read/28343759/incidence-of-postsuppression-virologic-rebound-in-perinatally-hiv-infected-asian-adolescents-on-stable-combination-antiretroviral-therapy
#17
Tavitiya Sudjaritruk, Linda Aurpibul, Penh Sun Ly, Thoa Phan Kim Le, Torsak Bunupuradah, Rawiwan Hansudewechakul, Pagakrong Lumbiganon, Kulkanya Chokephaibulkit, Nik Khairulddin Nik Yusoff, Lam Van Nguyen, Kamarul Azahar Mohd Razali, Moy Siew Fong, Revathy A Nallusamy, Nia Kurniati, Viet Chau Do, David C Boettiger, Annette H Sohn, Azar Kariminia
PURPOSE: To assess the incidence and predictors of postsuppression virologic rebound (VR) among adolescents on stable combination antiretroviral therapy in Asia. METHODS: Perinatally HIV-infected Asian adolescents (10-19 years) with documented virologic suppression (two consecutive viral loads [VLs] <400 copies/mL ≥6 months apart) were included. Baseline was the date of the first VL <400 copies/mL at age ≥10 years or the 10th birthday for those with prior suppression...
March 23, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28343405/htlv-1-associated-myelopathy-tropical-spastic-paraparesis-the-first-case-report-in-southeast-asia
#18
Sekh Thanprasertsuk, Suwapan Pleumkanitkul, Supaporn Wacharapluesadee, Teerada Ponpinit, Thiravat Hemachudha, Chusana Suankratay
Human T-lymphotropic virus type-1 (HTLV-1) infection was diagnosed in a Thai patient with chronic progressive myelopathy. The phylogenetic tree of the ltr sequencing of HTLV-1 indicated the virus belongs to the Transcontinental genotype of the Cosmopolitan subtype A. This is the first case report of HTLV-1-associated myelopathy in South East Asia. Awareness of HTLV-1 and related condition should be encouraged in this region and routine screening should be applied in blood donor.
March 26, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28343316/translation-and-validation-of-iciq-fluts-for-tamil-speaking-women
#19
Chanil D Ekanayake, Arunasalam Pathmeswaran, A A Nilanga Nishad, Kanishka U Samaranayake, Prasantha S Wijesinghe
AIMS: Research in to lower urinary tract symptoms (LUTS) in women in South Asia is hampered by lack of validated tools. Our aim was to validate the International Consultation on Incontinence Modular Questionnaire on Female Lower Urinary Tract Symptoms (ICIQ-FLUTS) from English to Tamil. METHOD: After translation to Tamil, a validation study was carried out among women attending the gynecology clinic at District General Hospital-Mannar. RESULTS: Content validity assessed by the level of missing data was <2%...
March 25, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28343099/source-apportionments-of-ambient-fine-particulate-matter-in-israeli-jordanian-and-palestinian-cities
#20
Jongbae Heo, Bo Wu, Ziad Abdeen, Radwan Qasrawi, Jeremy A Sarnat, Geula Sharf, Kobby Shpund, James J Schauer
This manuscript evaluates spatial and temporal variations of source contributions to ambient fine particulate matter (PM2.5) in Israeli, Jordanian, and Palestinian cities. Twenty-four hour integrated PM2.5 samples were collected every six days over a 1-year period (January to December 2007) in four cities in Israel (West Jerusalem, Eilat, Tel Aviv, and Haifa), four cities in Jordan (Amman, Aqaba, Rahma, and Zarka), and three cities in Palestine (Nablus, East Jerusalem, and Hebron). The PM2.5 samples were analyzed for major chemical components, including organic carbon and elemental carbon, ions, and metals, and the results were used in a positive matrix factorization (PMF) model to estimate source contributions to PM2...
March 23, 2017: Environmental Pollution
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