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Primary spine ewing sarcoma

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https://www.readbyqxmd.com/read/27895949/primary-ewing-s-sarcoma-of-the-spine-in-a-two-year-old-boy
#1
Ali J Electricwala, Jaffer T Electricwala
Ewing's Sarcoma (ES) is a highly malignant bone tumour. It may involve any part of the skeleton but the most frequent parts are the ilium and diaphysis of femur and tibia (Alfeeli et al., 2005; Zhu et al., 2012). Primary ES of the spine is extremely rare (Yan et al., 2011). It accounts for only 3.5 to 14.9 percent of all primary bone sarcomas. The age of presentation ranges from 12 to 24 years (median 21 years) (Ferguson, 1999; Sharafuddin et al., 1992; Klimo Jr. et al., 2009). We report an unusual case of primary ES of the spine in a two-year-old boy, who presented to us with paraparesis and features of cauda equina syndrome...
2016: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/27856382/prognostic-determinants-and-treatment-outcomes-analysis-of-osteosarcoma-and-ewing-sarcoma-of-the-spine
#2
Armin Arshi, Justin Sharim, Don Y Park, Howard Y Park, Hamed Yazdanshenas, Nicholas M Bernthal, Arya N Shamie
BACKGROUND CONTEXT: Osteosarcoma (OGS) and Ewing sarcoma (EWS) are the two classic primary malignant bone tumors. Due to the rarity of these tumors, evidence on demographics, survival determinants, and treatment outcomes for primary disease of the spine are limited and derived from small case series. PURPOSE: To use population-level data to determine the epidemiology and prognostic indicators in patients with OGS and EWS of the osseous spine. STUDY DESIGN/SETTING: Large-scale retrospective study...
November 14, 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/26917429/primary-bone-tumors-of-the-spine
#3
A Navas Cañete, H L Bloem, H M Kroon
Primary bone tumors of the spine are less common than metastases or multiple myeloma. Based on the patient's age and the radiologic pattern and topography of the tumor, a very approximate differential diagnosis can be established for an osseous vertebral lesion. This article shows the radiologic manifestations of the principal primary bone tumors of the spine from a practical point of view, based on our personal experience and a review of the literature. If bone metastases, multiple myeloma, lymphomas, hemangiomas, and enostoses are excluded, only eight types of tumors account for 80% of all vertebral tumors...
April 2016: Radiología
https://www.readbyqxmd.com/read/26882852/primary-ewing-sarcoma-of-the-lumbar-spine-presenting-as-cauda-equina-syndrome-in-a-pediatric-patient
#4
Cahit Kafadar, Onur Levent Ulusoy, Ersin Ozturk, Ayhan Mutlu
No abstract text is available yet for this article.
September 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/26776236/a-rare-cause-of-low-back-pain-primary-ewing-sarcoma-of-the-lumbar-spine
#5
Hatice Resorlu, Adem B Aras, Coskun Zateri, Ferdi Goksel
No abstract text is available yet for this article.
July 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/26335676/reconstruction-of-the-upper-cervical-spine-using-a-personalized-3d-printed-vertebral-body-in-an-adolescent-with-ewing-sarcoma
#6
Nanfang Xu, Feng Wei, Xiaoguang Liu, Liang Jiang, Hong Cai, Zihe Li, Miao Yu, Fengliang Wu, Zhongjun Liu
STUDY DESIGN: Case report. OBJECTIVE: To describe a three-dimensional (3D) printed axial vertebral body used in upper cervical spine reconstruction after a C2 Ewing sarcoma resection in an adolescent boy. SUMMARY OF BACKGROUND DATA: Ewing sarcoma is a malignant musculoskeletal neoplasm with a peak incidence in adolescents. Cervical spine as the primary site of the tumor has been related to a worse prognosis. Tumor resection is particularly challenging in the atlantoaxial region due to complexity of the anatomy, necessity for extensive resection according to oncological principles, and a lack of specialized implants for reconstruction...
January 2016: Spine
https://www.readbyqxmd.com/read/26308634/the-neurological-compromised-spine-due-to-ewing-sarcoma-what-first-surgery-or-chemotherapy-therapy-survival-and-neurological-outcome-of-15-cases-with-primary-ewing-sarcoma-of-the-vertebral-column
#7
Lida Mirzaei, Suzanne E J Kaal, Hendrik W B Schreuder, Ronald H M A Bartels
BACKGROUND: The vertebral column is an infrequent site of primary involvement in Ewing sarcoma. Yet when Ewing sarcoma is found in the spine, the urge for decompression is high because of the often symptomatic compression of neural structures. It is unclear in alleviating a neurological deficit whether chemotherapy is preferred over decompressive laminectomy. OBJECTIVE: To underline, in this case series, the efficiency of initial chemotherapy before upfront surgery in the setting of high-grade spinal cord or cauda equina compression of primary Ewing sarcoma...
November 2015: Neurosurgery
https://www.readbyqxmd.com/read/25993237/chemotherapy-for-bone-sarcomas-in-adults-the-md-anderson-experience
#8
REVIEW
Robert S Benjamin, Michael J Wagner, J Andrew Livingston, Vinod Ravi, Shreyaskumar R Patel
Increasing age is an adverse prognostic factor in the treatment of primary bone tumors. There are few published data on treatment of primary bone tumors in adults. This paper presents data from the Department of Sarcoma Medical Oncology at The University of Texas MD Anderson Cancer Center, summarizing our treatment results. To treat primary osteosarcoma, we used 90 mg/m2 of doxorubicin as a continuous intravenous infusion over 48 to 96 hours and 120 to 160 mg/m2 of cisplatin intravenously or intra-arterially...
2015: American Society of Clinical Oncology Educational Book
https://www.readbyqxmd.com/read/25954672/unusual-presentation-of-a-primary-ewing-s-sarcoma-of-the-spine-with-paraplegia-a-case-report
#9
Karthik Kailash Kannan, Rajkumar Jayachandran Sundarapandian, Vignesh Jayabalan Surulivel
Ewing's sarcoma is a primary malignancy of the bone affecting individuals in the second decade of life. Primary sarcomas of the spine are rare and the occurrence of Primary Ewing's sarcoma in the spine is very rare. Ewing's sarcoma occurring in the spine is divided into two types, Ewing's sarcoma of sacral spine which are very aggressive with poor prognosis and Ewing's sarcoma of the non sacral spine which is an extremely rare occurrence. Patient may present with neurological deficit when the tumour extends into the spinal canal causing spinal cord compression...
March 2015: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/25802527/a-unique-case-of-primary-ewing-s-sarcoma-of-the-cervical-spine-in-a-53-year-old-male-a-case-report-and-review-of-the-literature
#10
Marshall T Holland, Oliver E Flouty, Liesl N Close, Chandan G Reddy, Matthew A Howard
Extraskeletal Ewing's sarcoma (EES) is a rare presentation, representing only 15% of all primary Ewing's sarcoma cases. Even more uncommon is EES presenting as a primary focus in the spinal canal. These rapidly growing tumors often present with focal neurological symptoms of myelopathy or radiculopathy. There are no classic characteristic imaging findings and thus the physician must keep a high index of clinical suspicion. Diagnosis can only be definitively made by histopathological studies. In this report, we discuss a primary cervical spine EES in a 53-year-old man who presented with a two-month history of left upper extremity pain and acute onset of weakness...
2015: Case Reports in Medicine
https://www.readbyqxmd.com/read/25724431/primary-extraosseous-ewing-sarcoma-of-the-lumbar-spine-presenting-with-left-leg-weakness
#11
Recep Sade, Mürteza Çakır, Hayri Ogul, Ihsan Yuce, Mecit Kantarci
No abstract text is available yet for this article.
June 1, 2015: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/25557999/developing-a-prognostic-model-for-localized-ewing-sarcoma-family-of-tumors-a-single-institutional-experience-of-224-cases-treated-with-uniform-chemotherapy-protocol
#12
Bivas Biswas, S Rastogi, S A Khan, N K Shukla, S V S Deo, S Agarwala, B K Mohanti, M C Sharma, Sreenivas Vishnubhatla, S Bakhshi
BACKGROUND: Data on patients with localized Ewing sarcoma family of tumors (ESFT) who have received a uniform chemotherapy protocol are minimal. METHODS: This is a single institutional review of patients with ESFT treated between June 2003 and November 2011. RESULTS: 224/374 (60%) patients with ESFT presented with localized disease; median age was 15 years (range: 0.1-55). Ninety-nine patients underwent surgery of which 50 received adjuvant radiotherapy; 80 patients received radical radiotherapy following neoadjuvant chemotherapy...
May 2015: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/24896744/primary-tumors-of-the-spine
#13
REVIEW
Sebnem Orguc, Remide Arkun
Spinal tumors consist of a large spectrum of various histologic entities. Multiple spinal lesions frequently represent known metastatic disease or lymphoproliferative disease. In solitary lesions primary neoplasms of the spine should be considered. Primary spinal tumors may arise from the spinal cord, the surrounding leptomeninges, or the extradural soft tissues and bony structures. A wide variety of benign neoplasms can involve the spine including enostosis, osteoid osteoma, osteoblastoma, aneurysmal bone cyst, giant cell tumor, and osteochondroma...
July 2014: Seminars in Musculoskeletal Radiology
https://www.readbyqxmd.com/read/24847440/fine-needle-aspiration-cytology-of-ewing-s-sarcoma-of-thoracic-spine-with-extension-into-the-intradural-space
#14
Sandhya Bordia, Sweta Meena, Bijendar Kumar Meena, Vijay Rajak
Ewing's sarcoma/peripheral primitive neuroectodermal tumor is a small, round, and blue cell malignancy that occurs most often in bone and soft tissues of children and young adults. The intraspinal manifestation of the disease is rare, and when present, this is often misdiagnosed with other varieties of primary spinal tumors. Fine-needle aspiration cytology (FNAC) plays important role in the early diagnosis of these cases. We report such a case of Ewing's sarcoma of thoracic spine with extension into the intradural space, which was initially suspected to be a case of metastatic lesion in an 18-year-old boy...
2014: Case Reports in Oncological Medicine
https://www.readbyqxmd.com/read/24760406/surgical-treatment-of-sarcomas-of-the-spine
#15
REVIEW
Ali K Ozturk, Ziya L Gokaslan, Jean-Paul Wolinsky
Primary sarcomas of the spine are rare diseases and include osteosarcoma, chondrosarcoma, chordoma, and Ewing's sarcoma. Surgery for these lesions remains an important part of their treatment. Strong evidence exists for the en bloc resection of chondrosarcoma and chordoma since these lesions respond poorly to both chemotherapy and radiation. Weaker but important evidence suggests that osteosarcoma and Ewing's sarcoma may also benefit from wide excisions, but after the application of neoadjuvant therapy, which may significantly aid the surgical process as well as independently prolong the survival...
September 2014: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/24716731/surgical-management-of-primary-tumors-of-the-cervical-spine-surgical-considerations-and-avoidance-of-complications
#16
REVIEW
Paul E Kaloostian, Ziya L Gokaslan
OBJECTIVE: Primary cervical spinal tumors are rare tumors of the spine and are associated with significant morbidity and mortality. Such tumors include multiple myeloma, chordomas, giant cell tumors, hemangiomas, osteosarcomas, chondrosarcomas, synovial sarcomas, aneurysmal bone cysts (ABC), hemangiomas, eosinophilic granulomas, osteoid osteomas, and osteoblastomas. We review the surgical decision-making process and identify critical key steps for surgical complication avoidance. We also present case illustrations demonstrating such pathological diagnoses and surgical treatments performed...
June 2014: Neurological Research
https://www.readbyqxmd.com/read/24437986/primary-atlantoaxial-bone-tumors-in-children-management-strategies-and-long-term-follow-up
#17
Arnold H Menezes, Raheel Ahmed
OBJECT: Atlantoaxial tumors account for a substantial proportion of primary bone tumors in children. Before resection, surgeons must consider the complex regional anatomy, the potential for neurological compromise, craniocervical instability, and the question of tumor resectability in a growing spine. Using current technology, the authors analyzed surgical cases in this light and present outcomes and treatment recommendations after long-term patient follow-up. METHODS: The authors reviewed clinical records for 23 children whose primary atlantoaxial bone tumors were treated from 1996 through 2010...
March 2014: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/23657430/magnetic-resonance-imaging-appearance-of-primary-spinal-extradural-ewing-s-sarcoma-case-report-and-literature-review
#18
REVIEW
S Tsutsumi, Y Yasumoto, A Manabe, I Ogino, H Arai, M Ito
PURPOSE: Primary spinal extradural Ewing's sarcoma (PSEES) or primitive neuroectodermal tumor (PNET) is uncommon. The present study summarizes the magnetic resonance (MR) imaging appearance of PSEES. METHODS: Literature search from 1994 to 2012 with our representative case presentation. RESULTS: Twenty-one patients, 12 males and 9 females, aged 3 weeks to 44 years, were identified. The thoracic spine was most frequently affected, followed by the cervical, cervicothoracic, and thoracolumbar spine...
June 2013: Clinical Neuroradiology
https://www.readbyqxmd.com/read/23623034/spontaneous-oral-extrusion-of-an-acrylic-vertebral-reconstruction-12-years-after-a-vertebrectomy-for-a-ewing-s-sarcoma-of-the-cervical-spine-a-case-report
#19
R Faguer, D Petit, P Menei, H-D Fournier
INTRODUCTION: Primary Ewing sarcoma of the cervical spine is rare, particularly in children population. The surgical management remains a challenge to associate the best oncological resection and to prevent spinal deformity. The situation is complicated owing to paucity of adapted instrumentation and their possible interactions with the growing bone. CLINICAL PRESENTATION: We described the case of a young 19-year-old woman admitted for an oral extrusion of a bone polymethyl methacrylate (PMMA) allograft 12 years after a C4 circumferential vertebrectomy for primary Ewing's sarcoma...
April 2013: Neuro-Chirurgie
https://www.readbyqxmd.com/read/23472623/primary-intradural-extraosseous-ewing-s-sarcoma-of-the-lumbar-spine-presenting-with-acute-bleeding
#20
M R Khalatbari, H Jalaeikhoo, Y Moharamzad
We report the case of a 28-year-old female with primary extraosseous Ewing's sarcoma who presented initially with a low back pain and a right S1 radicular pain. Before scheduled surgical removal, she suddenly developed an unusual complication of an acute hemorrhage and an acute cauda equina syndrome. Emergency surgery was done which demonstrated an acute bleeding. Treatment was followed by the chemotherapy and the adjuvant radiotherapy. Follow-up has been done for 6 years after presentation.
December 2013: British Journal of Neurosurgery
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