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https://www.readbyqxmd.com/read/28144686/-new-technical-developments-for-inhaled-sedation
#1
A Meiser, H Bomberg, T Volk, H V Groesdonk
The circle system has been in use for more than 100 years, whereas the first clinical application of an anaesthetic reflector was reported just 15 years ago. In the circle system, all breathing gas is rebreathed after carbon dioxide absorption. A reflector, on the other hand, with the breathing gas flowing to and fro, specifically retains the anaesthetic during expiration and resupplies it during the next inspiration. A high reflection efficiency (number of molecules resupplied/number of molecules exhaled, RE 80-90%) decreases consumption...
January 31, 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/28048560/tu-h-campus-jep1-04-deformable-image-registration-performances-in-pelvis-patients-impact-of-cbct-image-quality
#2
M Fusella, G Loi, C Fiandra, E Lanzi
PURPOSE: To investigate the accuracy and robustness, against image noise and artifacts (typical of CBCT images), of a commercial algorithm for deformable image registration (DIR), to propagate regions of interest (ROIs) in computational phantoms based on real prostate patient images. METHODS: The Anaconda DIR algorithm, implemented in RayStation was tested. Two specific Deformation Vector Fields (DVFs) were applied to the reference data set (CTref) using the ImSimQA software, obtaining two deformed CTs...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046332/su-d-202-04-validation-of-deformable-image-registration-algorithms-for-head-and-neck-adaptive-radiotherapy-in-routine-clinical-setting
#3
L Zhang, Z Wang, C Shi, Y Pi, T Long, W Luo, F Wang, Z Chen, X Xu
PURPOSE: To evaluate the ROI contours and accumulated dose difference using different deformable image registration (DIR) algorithms for head and neck (H&N) adaptive radiotherapy. METHODS: Eight H&N cancer patients were randomly selected from the affiliated hospital. During the treatment, patients were rescanned every week with ROIs well delineated by radiation oncologist on each weekly CT. New weekly treatment plans were also re-designed with consistent dose prescription on the rescanned CT and executed for one week on Siemens CT-on-rails accelerator...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28029566/midterm-results-of-the-fenestrated-anaconda-endograft-for-short-neck-infrarenal-and-juxtarenal-abdominal-aortic-aneurysm-repair
#4
Louise L Blankensteijn, Martijn L Dijkstra, Ignace F J Tielliu, Michel M P J Reijnen, Clark J Zeebregts
OBJECTIVE: The fenestrated Anaconda endograft (Vascutek, Renfrewshire, Scotland) was introduced in 2010 and showed promising short-term results with high technical success and low morbidity rates. The aim of this study was to present the midterm results, with a minimum of 12 months follow-up, for all patients treated with the fenestrated Anaconda endograft in The Netherlands. METHODS: Patients treated with the fenestrated Anaconda endograft between May 2011 and February 2015 were included...
February 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27938703/detection-and-prevalence-of-boid-inclusion-body-disease-in-collections-of-boas-and-pythons-using-immunological-assays
#5
L Chang, D Fu, M D Stenglein, J A Hernandez, J L DeRisi, E R Jacobson
Inclusion body disease (IBD) of boas and pythons is characterized by the intracytoplasmic accumulation of an antigenic 68 kDa viral protein IBDP, more recently known as the nucleoprotein (NP) of the reptarenaviruses. Blood samples of 131 captive boas and pythons (53 boa constrictors, Boa constrictor; 35 rainbow boas, Epicrates cenchria; 22 ball pythons, Python regius; 5 carpet pythons, Morelia spilota; 6 Burmese pythons, Python bivittatus; 4 Jamaican boas, Epicrates subflavus; 5 anacondas, Eunectes spp.; and 1 green tree python, Morelia viridis) were obtained from 28 collections in the USA...
December 2016: Veterinary Journal
https://www.readbyqxmd.com/read/27903013/isoflurane-associated-mydriasis-mimicking-blown-pupils-in-a-patient-treated-in-a-neurointensive-care-unit
#6
Eva Magdalena Korf, Volker Martin Tronnier, Jan Gliemroth, Jan Nils Küchler
We report a misinterpretation of bilateral mydriasis as blown pupils related to elevated intracranial pressure (ICP) under volatile sedation with isoflurane (Anesthetic Conserving Device [AnaConDa], Hudson RCI, Uppland Vasby, Sweden) in a 59-year-old patient with a severe traumatic brain injury with frontal contusion. The patient showed bilateral mydriasis and a missing light reflex 8 hours after changing sedation from intravenous treatment with midazolam and esketamine to volatile administration of isoflurane...
November 30, 2016: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/27875262/autoregulation-of-cardiac-output-is-overcome-by-adrenergic-stimulation-in-the-anaconda-heart
#7
William Joyce, Michael Axelsson, Tobias Wang
Most vertebrates increase cardiac output during activity by elevating heart rate with relatively stable stroke volume. However, several studies have demonstrated 'intrinsic autoregulation' of cardiac output where artificially increased heart rate is associated with decreased stroke volume, leaving cardiac output unchanged. We explored the capacity of noradrenaline to overcome autoregulation in the anaconda heart. Electrically pacing in situ perfused hearts from the intrinsic heart rate to the maximum attainable resulted in a proportional decrease in stroke volume...
November 10, 2016: Journal of Experimental Biology
https://www.readbyqxmd.com/read/27728949/fenestrated-endografts-for-complex-abdominal-aortic-aneurysm-repair
#8
Arne de Niet, Michel Mpj Reijnen, Ignace Fj Tielliu, Jan Willem Hp Lardenoije, Clark J Zeebregts
Since the introduction of fenestrated endovascular aneurysm repair (FEVAR) in 1996, great advances have been made in endograft development. Custom-made and off-the-shelf fenestrated and branched endografts have been used to treat patients with complex abdominal aortic and thoraco-abdominal aneurysms. Most experience has been gained with the Cook Zenith® fenestrated endograft (Cook Medical Inc., Limerick, Ireland). The Cook Zenith® endograft is customized with fenestrations, (fixed) inner or outer branches, or a combination of them, to cover a wide range of complex aneurysms...
October 6, 2016: Surgical Technology International
https://www.readbyqxmd.com/read/27594350/structural-implications-of-fenestrated-stent-graft-misalignment
#9
S A Crawford, M Itkina, M G Doyle, L W Tse, C H Amon, G Roche-Nagle
BACKGROUND: Endovascular aneurysm repair is a minimally-invasive method for the treatment of abdominal aortic aneurysms. For aneurysms that involve the visceral arteries, a custom-made stent graft with fenestrations for the branch arteries is required. The purpose of the current study is to evaluate the structural impact of misaligned fenestrations with respect to luminal patency and proximal aortic neck apposition in an in vitro model. METHODS: A custom apparatus was used to evaluate seven Anaconda and three Zenith fenestrated stent grafts...
September 1, 2016: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/27573021/operative-and-midterm-outcomes-of-the-fenestrated-anaconda-stent-graft-in-the-endovascular-treatment-of-juxtarenal-suprarenal-and-type-iv-thoracoabdominal-aortic-aneurysms
#10
Drosos Kotelis, Karina Schleimer, Houman Jalaie, Jochen Grommes, Michael J Jacobs, Johannes Kalder
PURPOSE: To report operative and midterm outcomes of fenestrated endovascular aneurysm repair (FEVAR) with the Anaconda device. METHODS: A retrospective analysis was conducted of 39 consecutive patients (median age 74 years; 36 men) treated with the fenestrated Anaconda stent-graft between July 2011 and December 2015 at a single center. Indications for FEVAR were abdominal aortic aneurysms (AAAs) with neck anatomy unsuitable for a standard stent-graft. Median infrarenal neck length was 4 mm (range 0-9)...
August 29, 2016: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/27552931/single-centre-results-of-total-endovascular-repair-of-complex-aortic-aneurysms-with-custom-made-anaconda-fenestrated-stent-grafts
#11
R Shahverdyan, D Gray, M Gawenda, J Brunkwall
OBJECTIVE: Fenestrated endovascular aneurysm repair (F-EVAR) has increased the number of patients with aneurysmal disease and a short or no existing neck being eligible for endovascular treatment. The aim of the study is to report experience using the Anaconda fenestrated device with special emphasis on target vessel patency and pitfalls with the device. METHODS: Between 2011 and 2016, 48 F-EVAR procedures were performed in 37 males and 11 females under general anaesthesia using the Anaconda custom made device (CMD)...
October 2016: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/27539918/reassessing-the-link-between-airborne-arsenic-exposure-among-anaconda-copper-smelter-workers-and-multiple-causes-of-death-using-the-parametric-g-formula
#12
Alexander P Keil, David B Richardson
BACKGROUND: Prior studies have indicated associations between ingestion of inorganic arsenic and ischemic heart disease, non-malignant respiratory disease, and lung, skin, bladder and kidney cancers. In contrast, inhaled arsenic has been consistently associated only with lung cancer. Evidence for health effects of inhaled arsenic derives mainly from occupational studies that are subject to unique biases that may attenuate or obscure such associations. OBJECTIVES: Estimate the excess mortality from respiratory cancers, heart disease, and other causes due to occupational arsenic exposure while controlling for confounding using the parametric g-formula...
August 19, 2016: Environmental Health Perspectives
https://www.readbyqxmd.com/read/27427345/technical-notes-for-treatment-of-a-pluri-relapsing-iliac-and-femoral-pseudoaneurysm
#13
Emiliano Chisci, Enrico Barbanti, Eugenio Romano, Nicola Troisi, Leonardo Ercolini, Stefano Michelagnoli
BACKGROUND: To describe a technique that connects an Anaconda stent graft (Vascutek, Terumo, Inchinnan, Scotland) to a target artery in a hybrid method. CASE REPORT: The patient was a 65-year-old man with a huge pluri-relapsing iliac and femoral pseudoaneurysm of a previous aortobifemoral bypass. An Anaconda stent graft was used to repair the lesion. After partial dissection of the femoral bifurcation, the Anaconda stent graft was partially introduced via a direct puncture in the anterior wall of the femoral artery over a guidewire...
October 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27392660/evaluating-the-efficiency-of-desflurane-reflection-in-two-commercially-available-reflectors
#14
Hagen Bomberg, Marcel Wessendorf, Martin Bellgardt, Max Veddeler, Stefan Wagenpfeil, Thomas Volk, Heinrich V Groesdonk, Andreas Meiser
With the AnaConDa™ and the MIRUS™ system, volatile anesthetics can be administered for inhalation sedation in intensive care units. Instead of a circle system, both devices use anesthetic reflectors to save on the anesthetic agent. We studied the efficiency of desflurane reflection with both devices using different tidal volumes (VT), respiratory rates (RR), and 'patient' concentrations (CPat) in a bench study. A test lung was ventilated with four settings (volume control, RR × VT: 10 × 300 mL, 10 × 500 mL, 20 × 500 mL, 10 × 1000 mL)...
July 8, 2016: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/27362849/sevoflurane-therapy-for-severe-refractory-bronchospasm-in-children
#15
Alba Palacios, Santiago Mencía, Ana M Llorente, Jaime Cruz, Blanca Toledo, Olga Ordóñez, Marta Olmedilla, Jesus Lopez-Herce
OBJECTIVES: To describe the effect of inhaled sevoflurane in the treatment of severe refractory bronchospasm in children. DESIGN: Retrospective case series. SETTING: Two PICUs of tertiary general university hospitals in Spain. PATIENTS: Ten patients ranging from 5 months to 14 years old with severe bronchospasm and acute respiratory failure requiring tracheal intubation and mechanical ventilation and treated with sevoflurane from 2008 to 2015...
August 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27207643/in-situ-cardiac-perfusion-reveals-interspecific-variation-of-intraventricular-flow-separation-in-reptiles
#16
William Joyce, Michael Axelsson, Jordi Altimiras, Tobias Wang
The ventricles of non-crocodilian reptiles are incompletely divided and provide an opportunity for mixing of oxygen-poor blood and oxygen-rich blood (intracardiac shunting). However, both cardiac morphology and in vivo shunting patterns exhibit considerable interspecific variation within reptiles. In the present study, we develop an in situ double-perfused heart approach to characterise the propensity and capacity for shunting in five reptile species: the turtle Trachemys scripta, the rock python Python sebae, the yellow anaconda Eunectes notaeus, the varanid lizard Varanus exanthematicus and the bearded dragon Pogona vitticeps To simulate changes in vascular bed resistance, pulmonary and systemic afterloads were independently manipulated and changes in blood flow distribution amongst the central outflow tracts were monitored...
July 15, 2016: Journal of Experimental Biology
https://www.readbyqxmd.com/read/27174351/endovascular-treatment-of-infrarenal-aneurysms-comparison-of-the-results-of-second-and-third-generation-stent-grafts
#17
COMPARATIVE STUDY
Antoine Maudet, Anne Daoudal, Alain Cardon, Elodie Clochard, Antoine Lucas, Jean-Philippe Verhoye, Adrien Kaladji
BACKGROUND: The stent grafts used for endovascular abdominal aortic repair (EVAR) profited from many technological changes since their appearance. The objective of this study was to compare the medium-term results of the second- and third-generation stent grafts. METHODS: Three hundred thirty-four patients treated by EVAR between 2005 and 2013 were included in this retrospective study. Demographic, anatomical, perioperative, and follow-up data were collected in a prospective way in an electronic database and compared between 2 groups...
July 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27099825/anaconda%C3%A2-and-mirus%C3%A2-for-intensive-care-sedation-24%C3%A2-h-desflurane-versus-isoflurane-in-one-patient
#18
Hagen Bomberg, Heinrich V Groesdonk, Martin Bellgardt, Thomas Volk, Andreas Meiser
INTRODUCTION: With the AnaConDa™ system, inhalational sedation in the intensive care unit has become popular. The device can be used with common intensive care unit ventilators and is inserted between the Y-piece and the patient. Liquid isoflurane or sevoflurane are delivered by a syringe pump. 90 % of anesthetic exhaled by the patient is absorbed by a reflector and resupplied during the next inspiration. The new Mirus™ system also uses a reflector. Its control unit identifies end-tidal concentrations from the flow, injects anesthetics during early inspiration, controls anesthetic concentrations automatically, and can also apply desflurane...
2016: SpringerPlus
https://www.readbyqxmd.com/read/26637838/use-of-the-off-the-shelf-t-branch-device-to-treat-an-acute-type-ia-endoleak-in-a-symptomatic-juxtarenal-abdominal-aortic-aneurysm
#19
Adib Khanafer, Manar Khashram, Carmen-Maria Ruiz, Dana Mann, Andrew Laing
PURPOSE: To report the use of the off-the-shelf Zenith t-Branch Thoracoabdominal Endovascular Graft for the treatment of a symptomatic acute type Ia endoleak subsequent to previous infrarenal bifurcated endovascular aneurysm repair. CASE REPORT: A 72-year-old man presented 4 years after implantation of an Anaconda stent-graft with sac expansion and type II endoleak, which was treated over the next 18 months with repeated coil and glue embolization of the leak and sac...
February 2016: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/26530724/phyluce-is-a-software-package-for-the-analysis-of-conserved-genomic-loci
#20
Brant C Faircloth
UNLABELLED: Targeted enrichment of conserved and ultraconserved genomic elements allows universal collection of phylogenomic data from hundreds of species at multiple time scales (<5 Ma to > 300 Ma). Prior to downstream inference, data from these types of targeted enrichment studies must undergo preprocessing to assemble contigs from sequence data; identify targeted, enriched loci from the off-target background data; align enriched contigs representing conserved loci to one another; and prepare and manipulate these alignments for subsequent phylogenomic inference...
March 1, 2016: Bioinformatics
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