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https://www.readbyqxmd.com/read/28945023/-research-and-application-of-hepatotoxicity-evaluation-technique-of-traditional-chinese-medicine
#1
REVIEW
Jie Song, Rong-Ling Zhong, Zhi Xia, Hao Wu, Qing-Xiang Zhong, Zhen-Hai Zhang, Ying-Jie Wei, Zi-Qi Shi, Liang Feng, Xiao-Bin Jia
The safety of traditional Chinese medicine (TCM) has received the widespread attention in recent years. Hepatotoxicity of TCM is one of the key problems of the safety of TCM. This article summarized research progress and application prospect in the mechanism of TCM hepatotoxicity, biomarkers, toxic omics database, prevention of hepatotoxicity of the liver cell lines, subcellular fraction, three-dimensional cultivation models, the model animals, aiming to provide theoretical basis for TCM toxicity evaluation and technical guidelines, thus promoting the development of TCM toxicity studies...
January 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28944995/comparative-analysis-of-serum-proteome-in-congenital-scoliosis-patients-with-tbx6-haploinsufficiency-a-first-report-pointing-to-lipid-metabolism
#2
Qiankun Zhu, Nan Wu, Gang Liu, Yangzhong Zhou, Sen Liu, Jun Chen, Jiaqi Liu, Yuzhi Zuo, Zhenlei Liu, Weisheng Chen, Yixin Chen, Jia Chen, Mao Lin, Yanxue Zhao, Yang Yang, Shensgru Wang, Xu Yang, Yufen Ma, Jian Wang, Xiaoli Chen, Jianguo Zhang, Jianxiong Shen, Zhihong Wu, Guixing Qiu
Congenital scoliosis (CS) is a three-dimensional deformity of the spine affecting quality of life. We have demonstrated TBX6 haploinsufficiency is the most important contributor to CS. However, the pathophysiology at the protein level remains unclear. Therefore, this study was to explore the differential proteome in serum of CS patients with TBX6 haploinsufficiency. Sera from nine CS patients with TBX6 haploinsufficiency and nine age- and gender-matched healthy controls were collected and analysed by isobaric tagged relative and absolute quantification (iTRAQ) labelling coupled with mass spectrometry (MS)...
September 25, 2017: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/28944810/microfluidic-step-emulsification-in-axisymmetric-geometry
#3
I Chakraborty, J Ricouvier, P Yazhgur, P Tabeling, A M Leshansky
Biphasic step-emulsification (Z. Li et al., Lab Chip, 2015, 15, 1023) is a promising microfluidic technique for high-throughput production of μm and sub-μm highly monodisperse droplets. The step-emulsifier consists of a shallow (Hele-Shaw) microchannel operating with two co-flowing immiscible liquids and an abrupt expansion (i.e., step) to a deep and wide reservoir. Under certain conditions the confined stream of the disperse phase, engulfed by the co-flowing continuous phase, breaks into small highly monodisperse droplets at the step...
September 25, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28944673/exploring-antipolar-nature-of-methylammonium-lead-halides-a-monte-carlo-and-pyrocurrent-study
#4
Mantas Šimėnas, Sergejus Balciunas, Miroslaw Maczka, Juras Banys, Evaldas E Tornau
The high power conversion efficiency of the hybrid CH3NH3PbX3 (where X = I, Br, Cl) solar cells is believed to be tightly related to the dynamics and arrangement of the methylammonium cations. In this Letter, we propose a statistical phase transition model which accurately describes the ordering of the CH3NH3(+) cations and the whole phase transition sequence of the CH3NH3PbI3 perovskite. The model is based on the available structural information and involves the short-range strain-mediated and long-range dipolar interactions between the cations...
September 25, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28944395/combined-measurement-of-directional-raman-scattering-and-surface-plasmon-polariton-cone-from-adsorbates-on-smooth-planar-gold-surfaces
#5
Charles K A Nyamekye, Stephen C Weibel, Jonathan M Bobbitt, Emily A Smith
Directional-surface-plasmon-coupled Raman scattering (directional RS) has the combined benefits of surface plasmon resonance and Raman spectroscopy, and provides the ability to measure adsorption and monolayer-sensitive chemical information. Directional RS is performed by optically coupling a 50 nm gold film to a Weierstrass prism in the Kretschmann configuration and scanning the angle of the incident laser under total internal reflection. The collected parameters on the prism side of the interface include a full surface-plasmon-polariton cone and the full Raman signal radiating from the cone as a function of incident angle...
September 25, 2017: Analyst
https://www.readbyqxmd.com/read/28944383/-open-top-microfluidic-device-for-in-vitro-three-dimensional-capillary-beds
#6
Soojung Oh, Hyunryul Ryu, Dongha Tahk, Jihoon Ko, Yoojin Chung, Hae Kwang Lee, Tae Ryong Lee, Noo Li Jeon
We introduce a novel microfluidic device to co-culture a blood vessel network and cell tissues in an in vivo-like niche. Our "open-top" microfluidic device is composed of microchannels with micropores in the ceiling, which provides direct fluid access from reservoir to microchannel. Fluid connections through micropores afford novel advantages, including: i) the long-term culture of large-scale microvessel network, ii) access of different fluids to inner and exterior sides of the microvessel, and iii) co-culturing of the microvessel network and small cell tissue...
September 25, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28944086/development-of-spinal-deformities-in-the-tight-skin-mouse
#7
Bing Li, Jill Pg Urban, Jing Yu
Tight-skin (TSK) mice are commonly used as an animal model to study the pathogenesis of Marfan syndrome (MFS), but little is known of their skeletal phenotype and in particular of the development of the spinal deformities, common in MFS. Here we examined growth of the axial skeletons of TSK and wild-type(B6) mice during their period of rapid growth. The whole bodies of mice, 4-12 weeks of age, were scanned after sacrifice, by micro-computed tomography (microCT). We reconstructed three-dimensional models of the spine and ribs, and measured vertebral body heights and rib lengths using the Mac-based image-processing software "OsiriX"...
2017: Bone Research
https://www.readbyqxmd.com/read/28943965/dosimetric-comparison-and-observation-of-three-dimensional-conformal-radiotherapy-for-recurrent-nasopharyngeal-carcinoma
#8
Rongqiang Pan, Jingming Wang, Feng Qi, Ruizhen Liu
The aim of the study was to investigate the effect of three-dimensional conformal radiation therapy (3D-CRT) on nasopharyngeal carcinoma (NPC) and the incidence of complications. Between May 2010 and June 2012, 141 patients diagnosed with local recurrence of NPC due to cranial base lesions or cranial nerve symptoms, confirmed by pathology biopsy and/or by CT/MRI, were included in the present study. In accordance with the principle of randomized control, the patients were divided into three groups and treated with three different doses of 3D-CRT...
October 2017: Oncology Letters
https://www.readbyqxmd.com/read/28943927/measurement-of-exhaled-nitric-oxide-and-serum-surfactant-protein-d-levels-for-monitoring-radiation-pneumonitis-following-thoracic-radiotherapy
#9
Hideya Yamazaki, Norihiro Aibe, Satoaki Nakamura, Naomi Sasaki, Gen Suzuki, Ken Yoshida, Kei Yamada, Masahiko Koizumi, Taichiro Arimoto, Yoshinobu Iwasaki, Yoshiko Kaneko, Koichi Takayama
The present study aimed to examine the role of exhaled nitric oxide (eNO) and serum surfactant protein D (SP-D) level in the determination of radiation pneumonitis (RP) after thoracic radiotherapy (RT). The study included 34 treatments for 33 patients, including 16 three-dimensional conformal and 18 stereotactic body RT treatments. eNO levels were measured prior to RT, immediately subsequent to RT, every week during the RT course and at 1, 3, 6, 9 and 12 months following the treatment. The therapy reduced the eNO from 24...
October 2017: Oncology Letters
https://www.readbyqxmd.com/read/28943797/topological-cell-clustering-in-the-atlas-calorimeters-and-its-performance-in-lhc-run-1
#10
G Aad, B Abbott, J Abdallah, O Abdinov, R Aben, M Abolins, O S AbouZeid, H Abramowicz, H Abreu, R Abreu, Y Abulaiti, B S Acharya, L Adamczyk, D L Adams, J Adelman, S Adomeit, T Adye, A A Affolder, T Agatonovic-Jovin, J Agricola, J A Aguilar-Saavedra, S P Ahlen, F Ahmadov, G Aielli, H Akerstedt, T P A Åkesson, A V Akimov, G L Alberghi, J Albert, S Albrand, M J Alconada Verzini, M Aleksa, I N Aleksandrov, C Alexa, G Alexander, T Alexopoulos, M Alhroob, G Alimonti, L Alio, J Alison, S P Alkire, B M M Allbrooke, P P Allport, A Aloisio, A Alonso, F Alonso, C Alpigiani, A Altheimer, B Alvarez Gonzalez, D Álvarez Piqueras, M G Alviggi, B T Amadio, K Amako, Y Amaral Coutinho, C Amelung, D Amidei, S P Amor Dos Santos, A Amorim, S Amoroso, N Amram, G Amundsen, C Anastopoulos, L S Ancu, N Andari, T Andeen, C F Anders, G Anders, J K Anders, K J Anderson, A Andreazza, V Andrei, S Angelidakis, I Angelozzi, P Anger, A Angerami, F Anghinolfi, A V Anisenkov, N Anjos, A Annovi, M Antonelli, A Antonov, J Antos, F Anulli, M Aoki, L Aperio Bella, G Arabidze, Y Arai, J P Araque, A T H Arce, F A Arduh, J-F Arguin, S Argyropoulos, M Arik, A J Armbruster, O Arnaez, H Arnold, M Arratia, O Arslan, A Artamonov, G Artoni, S Artz, S Asai, N Asbah, A Ashkenazi, B Åsman, L Asquith, K Assamagan, R Astalos, M Atkinson, N B Atlay, K Augsten, M Aurousseau, G Avolio, B Axen, M K Ayoub, G Azuelos, M A Baak, A E Baas, M J Baca, C Bacci, H Bachacou, K Bachas, M Backes, M Backhaus, P Bagiacchi, P Bagnaia, Y Bai, T Bain, J T Baines, O K Baker, E M Baldin, P Balek, T Balestri, F Balli, W K Balunas, E Banas, Sw Banerjee, A A E Bannoura, L Barak, E L Barberio, D Barberis, M Barbero, T Barillari, M Barisonzi, T Barklow, N Barlow, S L Barnes, B M Barnett, R M Barnett, Z Barnovska, A Baroncelli, G Barone, A J Barr, F Barreiro, J Barreiro Guimarães da Costa, R Bartoldus, A E Barton, P Bartos, A Basalaev, A Bassalat, A Basye, R L Bates, S J Batista, J R Batley, M Battaglia, M Bauce, F Bauer, H S Bawa, J B Beacham, M D Beattie, T Beau, P H Beauchemin, R Beccherle, P Bechtle, H P Beck, K Becker, M Becker, M Beckingham, C Becot, A J Beddall, A Beddall, V A Bednyakov, C P Bee, L J Beemster, T A Beermann, M Begel, J K Behr, C Belanger-Champagne, W H Bell, G Bella, L Bellagamba, A Bellerive, M Bellomo, K Belotskiy, O Beltramello, O Benary, D Benchekroun, M Bender, K Bendtz, N Benekos, Y Benhammou, E Benhar Noccioli, J A Benitez Garcia, D P Benjamin, J R Bensinger, S Bentvelsen, L Beresford, M Beretta, D Berge, E Bergeaas Kuutmann, N Berger, F Berghaus, J Beringer, C Bernard, N R Bernard, C Bernius, F U Bernlochner, T Berry, P Berta, C Bertella, G Bertoli, F Bertolucci, C Bertsche, D Bertsche, M I Besana, G J Besjes, O Bessidskaia Bylund, M Bessner, N Besson, C Betancourt, S Bethke, A J Bevan, W Bhimji, R M Bianchi, L Bianchini, M Bianco, O Biebel, D Biedermann, N V Biesuz, M Biglietti, J Bilbao De Mendizabal, H Bilokon, M Bindi, S Binet, A Bingul, C Bini, S Biondi, D M Bjergaard, C W Black, J E Black, K M Black, D Blackburn, R E Blair, J-B Blanchard, J E Blanco, T Blazek, I Bloch, C Blocker, W Blum, U Blumenschein, S Blunier, G J Bobbink, V S Bobrovnikov, S S Bocchetta, A Bocci, C Bock, M Boehler, J A Bogaerts, D Bogavac, A G Bogdanchikov, C Bohm, V Boisvert, T Bold, V Boldea, A S Boldyrev, M Bomben, M Bona, M Boonekamp, A Borisov, G Borissov, S Borroni, J Bortfeldt, V Bortolotto, K Bos, D Boscherini, M Bosman, J Boudreau, J Bouffard, E V Bouhova-Thacker, D Boumediene, C Bourdarios, N Bousson, S K Boutle, A Boveia, J Boyd, I R Boyko, I Bozic, J Bracinik, A Brandt, G Brandt, O Brandt, U Bratzler, B Brau, J E Brau, H M Braun, W D Breaden Madden, K Brendlinger, A J Brennan, L Brenner, R Brenner, S Bressler, T M Bristow, D Britton, D Britzger, F M Brochu, I Brock, R Brock, J Bronner, G Brooijmans, T Brooks, W K Brooks, J Brosamer, E Brost, P A Bruckman de Renstrom, D Bruncko, R Bruneliere, A Bruni, G Bruni, M Bruschi, N Bruscino, L Bryngemark, T Buanes, Q Buat, P Buchholz, A G Buckley, I A Budagov, F Buehrer, L Bugge, M K Bugge, O Bulekov, D Bullock, H Burckhart, S Burdin, C D Burgard, B Burghgrave, S Burke, I Burmeister, E Busato, D Büscher, V Büscher, P Bussey, J M Butler, A I Butt, C M Buttar, J M Butterworth, P Butti, W Buttinger, A Buzatu, A R Buzykaev, S Cabrera Urbán, D Caforio, V M Cairo, O Cakir, N Calace, P Calafiura, A Calandri, G Calderini, P Calfayan, L P Caloba, D Calvet, S Calvet, R Camacho Toro, S Camarda, P Camarri, D Cameron, R Caminal Armadans, S Campana, M Campanelli, A Campoverde, V Canale, A Canepa, M Cano Bret, J Cantero, R Cantrill, T Cao, M D M Capeans Garrido, I Caprini, M Caprini, M Capua, R Caputo, R M Carbone, R Cardarelli, F Cardillo, T Carli, G Carlino, L Carminati, S Caron, E Carquin, G D Carrillo-Montoya, J R Carter, J Carvalho, D Casadei, M P Casado, M Casolino, D W Casper, E Castaneda-Miranda, A Castelli, V Castillo Gimenez, N F Castro, P Catastini, A Catinaccio, J R Catmore, A Cattai, J Caudron, V Cavaliere, D Cavalli, M Cavalli-Sforza, V Cavasinni, F Ceradini, L Cerda Alberich, B C Cerio, K Cerny, A S Cerqueira, A Cerri, L Cerrito, F Cerutti, M Cerv, A Cervelli, S A Cetin, A Chafaq, D Chakraborty, I Chalupkova, Y L Chan, P Chang, J D Chapman, D G Charlton, C C Chau, C A Chavez Barajas, S Che, S Cheatham, A Chegwidden, S Chekanov, S V Chekulaev, G A Chelkov, M A Chelstowska, C Chen, H Chen, K Chen, L Chen, S Chen, S Chen, X Chen, Y Chen, H C Cheng, Y Cheng, A Cheplakov, E Cheremushkina, R Cherkaoui El Moursli, V Chernyatin, E Cheu, L Chevalier, V Chiarella, G Chiarelli, G Chiodini, A S Chisholm, R T Chislett, A Chitan, M V Chizhov, K Choi, S Chouridou, B K B Chow, V Christodoulou, D Chromek-Burckhart, J Chudoba, A J Chuinard, J J Chwastowski, L Chytka, G Ciapetti, A K Ciftci, D Cinca, V Cindro, I A Cioara, A Ciocio, F Cirotto, Z H Citron, M Ciubancan, A Clark, B L Clark, P J Clark, R N Clarke, C Clement, Y Coadou, M Cobal, A Coccaro, J Cochran, L Coffey, J G Cogan, L Colasurdo, B Cole, S Cole, A P Colijn, J Collot, T Colombo, G Compostella, P Conde Muiño, E Coniavitis, S H Connell, I A Connelly, V Consorti, S Constantinescu, C Conta, G Conti, F Conventi, M Cooke, B D Cooper, A M Cooper-Sarkar, T Cornelissen, M Corradi, F Corriveau, A Corso-Radu, A Cortes-Gonzalez, G Cortiana, G Costa, M J Costa, D Costanzo, D Côté, G Cottin, G Cowan, B E Cox, K Cranmer, G Cree, S Crépé-Renaudin, F Crescioli, W A Cribbs, M Crispin Ortuzar, M Cristinziani, V Croft, G Crosetti, T Cuhadar Donszelmann, J Cummings, M Curatolo, J Cúth, C Cuthbert, H Czirr, P Czodrowski, S D'Auria, M D'Onofrio, M J Da Cunha Sargedas De Sousa, C Da Via, W Dabrowski, A Dafinca, T Dai, O Dale, F Dallaire, C Dallapiccola, M Dam, J R Dandoy, N P Dang, A C Daniells, M Danninger, M Dano Hoffmann, V Dao, G Darbo, S Darmora, J Dassoulas, A Dattagupta, W Davey, C David, T Davidek, E Davies, M Davies, P Davison, Y Davygora, E Dawe, I Dawson, R K Daya-Ishmukhametova, K De, R de Asmundis, A De Benedetti, S De Castro, S De Cecco, N De Groot, P de Jong, H De la Torre, F De Lorenzi, D De Pedis, A De Salvo, U De Sanctis, A De Santo, J B De Vivie De Regie, W J Dearnaley, R Debbe, C Debenedetti, D V Dedovich, I Deigaard, J Del Peso, T Del Prete, D Delgove, F Deliot, C M Delitzsch, M Deliyergiyev, A Dell'Acqua, L Dell'Asta, M Dell'Orso, M Della Pietra, D Della Volpe, M Delmastro, P A Delsart, C Deluca, D A DeMarco, S Demers, M Demichev, A Demilly, S P Denisov, D Derendarz, J E Derkaoui, F Derue, P Dervan, K Desch, C Deterre, K Dette, P O Deviveiros, A Dewhurst, S Dhaliwal, A Di Ciaccio, L Di Ciaccio, A Di Domenico, C Di Donato, A Di Girolamo, B Di Girolamo, A Di Mattia, B Di Micco, R Di Nardo, A Di Simone, R Di Sipio, D Di Valentino, C Diaconu, M Diamond, F A Dias, M A Diaz, E B Diehl, J Dietrich, S Diglio, A Dimitrievska, J Dingfelder, P Dita, S Dita, F Dittus, F Djama, T Djobava, J I Djuvsland, M A B do Vale, D Dobos, M Dobre, C Doglioni, T Dohmae, J Dolejsi, Z Dolezal, B A Dolgoshein, M Donadelli, S Donati, P Dondero, J Donini, J Dopke, A Doria, M T Dova, A T Doyle, E Drechsler, M Dris, Y Du, E Dubreuil, E Duchovni, G Duckeck, O A Ducu, D Duda, A Dudarev, L Duflot, L Duguid, M Dührssen, M Dunford, H Duran Yildiz, M Düren, A Durglishvili, D Duschinger, B Dutta, M Dyndal, C Eckardt, K M Ecker, R C Edgar, W Edson, N C Edwards, W Ehrenfeld, T Eifert, G Eigen, K Einsweiler, T Ekelof, M El Kacimi, M Ellert, S Elles, F Ellinghaus, A A Elliot, N Ellis, J Elmsheuser, M Elsing, D Emeliyanov, Y Enari, O C Endner, M Endo, J Erdmann, A Ereditato, G Ernis, J Ernst, M Ernst, S Errede, E Ertel, M Escalier, H Esch, C Escobar, B Esposito, A I Etienvre, E Etzion, H Evans, A Ezhilov, L Fabbri, G Facini, R M Fakhrutdinov, S Falciano, R J Falla, J Faltova, Y Fang, M Fanti, A Farbin, A Farilla, T Farooque, S Farrell, S M Farrington, P Farthouat, F Fassi, P Fassnacht, D Fassouliotis, M Faucci Giannelli, A Favareto, L Fayard, O L Fedin, W Fedorko, S Feigl, L Feligioni, C Feng, E J Feng, H Feng, A B Fenyuk, L Feremenga, P Fernandez Martinez, S Fernandez Perez, J Ferrando, A Ferrari, P Ferrari, R Ferrari, D E Ferreira de Lima, A Ferrer, D Ferrere, C Ferretti, A Ferretto Parodi, M Fiascaris, F Fiedler, A Filipčič, M Filipuzzi, F Filthaut, M Fincke-Keeler, K D Finelli, M C N Fiolhais, L Fiorini, A Firan, A Fischer, C Fischer, J Fischer, W C Fisher, N Flaschel, I Fleck, P Fleischmann, G T Fletcher, G Fletcher, R R M Fletcher, T Flick, A Floderus, L R Flores Castillo, M J Flowerdew, A Formica, A Forti, D Fournier, H Fox, S Fracchia, P Francavilla, M Franchini, D Francis, L Franconi, M Franklin, M Frate, M Fraternali, D Freeborn, S T French, S M Fressard-Batraneanu, F Friedrich, D Froidevaux, J A Frost, C Fukunaga, E Fullana Torregrosa, B G Fulsom, T Fusayasu, J Fuster, C Gabaldon, O Gabizon, A Gabrielli, A Gabrielli, G P Gach, S Gadatsch, S Gadomski, G Gagliardi, P Gagnon, C Galea, B Galhardo, E J Gallas, B J Gallop, P Gallus, G Galster, K K Gan, J Gao, Y Gao, Y S Gao, F M Garay Walls, F Garberson, C García, J E García Navarro, M Garcia-Sciveres, R W Gardner, N Garelli, V Garonne, C Gatti, A Gaudiello, G Gaudio, B Gaur, L Gauthier, P Gauzzi, I L Gavrilenko, C Gay, G Gaycken, E N Gazis, P Ge, Z Gecse, C N P Gee, Ch Geich-Gimbel, M P Geisler, C Gemme, M H Genest, C Geng, S Gentile, M George, S George, D Gerbaudo, A Gershon, S Ghasemi, H Ghazlane, B Giacobbe, S Giagu, V Giangiobbe, P Giannetti, B Gibbard, S M Gibson, M Gignac, M Gilchriese, T P S Gillam, D Gillberg, G Gilles, D M Gingrich, N Giokaris, M P Giordani, F M Giorgi, F M Giorgi, P F Giraud, P Giromini, D Giugni, C Giuliani, M Giulini, B K Gjelsten, S Gkaitatzis, I Gkialas, E L Gkougkousis, L K Gladilin, C Glasman, J Glatzer, P C F Glaysher, A Glazov, M Goblirsch-Kolb, J R Goddard, J Godlewski, S Goldfarb, T Golling, D Golubkov, A Gomes, R Gonçalo, J Goncalves Pinto Firmino Da Costa, L Gonella, S González de la Hoz, G Gonzalez Parra, S Gonzalez-Sevilla, L Goossens, P A Gorbounov, H A Gordon, I Gorelov, B Gorini, E Gorini, A Gorišek, E Gornicki, A T Goshaw, C Gössling, M I Gostkin, D Goujdami, A G Goussiou, N Govender, E Gozani, H M X Grabas, L Graber, I Grabowska-Bold, P O J Gradin, P Grafström, J Gramling, E Gramstad, S Grancagnolo, V Gratchev, H M Gray, E Graziani, Z D Greenwood, C Grefe, K Gregersen, I M Gregor, P Grenier, J Griffiths, A A Grillo, K Grimm, S Grinstein, Ph Gris, J-F Grivaz, S Groh, J P Grohs, A Grohsjean, E Gross, J Grosse-Knetter, G C Grossi, Z J Grout, L Guan, J Guenther, F Guescini, D Guest, O Gueta, E Guido, T Guillemin, S Guindon, U Gul, C Gumpert, J Guo, Y Guo, S Gupta, G Gustavino, P Gutierrez, N G Gutierrez Ortiz, C Gutschow, C Guyot, C Gwenlan, C B Gwilliam, A Haas, C Haber, H K Hadavand, N Haddad, P Haefner, S Hageböck, Z Hajduk, H Hakobyan, M Haleem, J Haley, D Hall, G Halladjian, G D Hallewell, K Hamacher, P Hamal, K Hamano, A Hamilton, G N Hamity, P G Hamnett, L Han, K Hanagaki, K Hanawa, M Hance, B Haney, P Hanke, R Hanna, J B Hansen, J D Hansen, M C Hansen, P H Hansen, K Hara, A S Hard, T Harenberg, F Hariri, S Harkusha, R D Harrington, P F Harrison, F Hartjes, M Hasegawa, Y Hasegawa, A Hasib, S Hassani, S Haug, R Hauser, L Hauswald, M Havranek, C M Hawkes, R J Hawkings, A D Hawkins, T Hayashi, D Hayden, C P Hays, J M Hays, H S Hayward, S J Haywood, S J Head, T Heck, V Hedberg, L Heelan, S Heim, T Heim, B Heinemann, L Heinrich, J Hejbal, L Helary, S Hellman, C Helsens, J Henderson, R C W Henderson, Y Heng, C Hengler, S Henkelmann, A Henrichs, A M Henriques Correia, S Henrot-Versille, G H Herbert, Y Hernández Jiménez, G Herten, R Hertenberger, L Hervas, G G Hesketh, N P Hessey, J W Hetherly, R Hickling, E Higón-Rodriguez, E Hill, J C Hill, K H Hiller, S J Hillier, I Hinchliffe, E Hines, R R Hinman, M Hirose, D Hirschbuehl, J Hobbs, N Hod, M C Hodgkinson, P Hodgson, A Hoecker, M R Hoeferkamp, F Hoenig, M Hohlfeld, D Hohn, T R Holmes, M Homann, T M Hong, W H Hopkins, Y Horii, A J Horton, J-Y Hostachy, S Hou, A Hoummada, J Howard, J Howarth, M Hrabovsky, I Hristova, J Hrivnac, T Hryn'ova, A Hrynevich, C Hsu, P J Hsu, S-C Hsu, D Hu, Q Hu, X Hu, Y Huang, Z Hubacek, F Hubaut, F Huegging, T B Huffman, E W Hughes, G Hughes, M Huhtinen, T A Hülsing, N Huseynov, J Huston, J Huth, G Iacobucci, G Iakovidis, I Ibragimov, L Iconomidou-Fayard, E Ideal, Z Idrissi, P Iengo, O Igonkina, T Iizawa, Y Ikegami, M Ikeno, Y Ilchenko, D Iliadis, N Ilic, T Ince, G Introzzi, P Ioannou, M Iodice, K Iordanidou, V Ippolito, A Irles Quiles, C Isaksson, M Ishino, M Ishitsuka, R Ishmukhametov, C Issever, S Istin, J M Iturbe Ponce, R Iuppa, J Ivarsson, W Iwanski, H Iwasaki, J M Izen, V Izzo, S Jabbar, B Jackson, M Jackson, P Jackson, M R Jaekel, V Jain, K B Jakobi, K Jakobs, S Jakobsen, T Jakoubek, J Jakubek, D O Jamin, D K Jana, E Jansen, R Jansky, J Janssen, M Janus, G Jarlskog, N Javadov, T Javůrek, L Jeanty, J Jejelava, G-Y Jeng, D Jennens, P Jenni, J Jentzsch, C Jeske, S Jézéquel, H Ji, J Jia, H Jiang, Y Jiang, S Jiggins, J Jimenez Pena, S Jin, A 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C Taccini, K Tackmann, J Taenzer, A Taffard, R Tafirout, N Taiblum, H Takai, R Takashima, H Takeda, T Takeshita, Y Takubo, M Talby, A A Talyshev, J Y C Tam, K G Tan, J Tanaka, R Tanaka, S Tanaka, B B Tannenwald, S Tapia Araya, S Tapprogge, S Tarem, F Tarrade, G F Tartarelli, P Tas, M Tasevsky, T Tashiro, E Tassi, A Tavares Delgado, Y Tayalati, A C Taylor, F E Taylor, G N Taylor, P T E Taylor, W Taylor, F A Teischinger, P Teixeira-Dias, K K Temming, D Temple, H Ten Kate, P K Teng, J J Teoh, F Tepel, S Terada, K Terashi, J Terron, S Terzo, M Testa, R J Teuscher, T Theveneaux-Pelzer, J P Thomas, J Thomas-Wilsker, E N Thompson, P D Thompson, R J Thompson, A S Thompson, L A Thomsen, E Thomson, M Thomson, R P Thun, M J Tibbetts, R E Ticse Torres, V O Tikhomirov, Yu A Tikhonov, S Timoshenko, E Tiouchichine, P Tipton, S Tisserant, K Todome, T Todorov, S Todorova-Nova, J Tojo, S Tokár, K Tokushuku, K Tollefson, E Tolley, L Tomlinson, M Tomoto, L Tompkins, K Toms, E Torrence, H Torres, E Torró Pastor, J Toth, F Touchard, D R Tovey, T Trefzger, L Tremblet, A Tricoli, I M Trigger, S Trincaz-Duvoid, M F Tripiana, W Trischuk, B Trocmé, C Troncon, M Trottier-McDonald, M Trovatelli, L Truong, M Trzebinski, A Trzupek, C Tsarouchas, J C-L Tseng, P V Tsiareshka, D Tsionou, G Tsipolitis, N Tsirintanis, S Tsiskaridze, V Tsiskaridze, E G Tskhadadze, K M Tsui, I I Tsukerman, V Tsulaia, S Tsuno, D Tsybychev, A Tudorache, V Tudorache, A N Tuna, S A Tupputi, S Turchikhin, D Turecek, R Turra, A J Turvey, P M Tuts, A Tykhonov, M Tylmad, M Tyndel, I Ueda, R Ueno, M Ughetto, F Ukegawa, G Unal, A Undrus, G Unel, F C Ungaro, Y Unno, C Unverdorben, J Urban, P Urquijo, P Urrejola, G Usai, A Usanova, L Vacavant, V Vacek, B Vachon, C Valderanis, N Valencic, S Valentinetti, A Valero, L Valery, S Valkar, S Vallecorsa, J A Valls Ferrer, W Van Den Wollenberg, P C Van Der Deijl, R van der Geer, H van der Graaf, N van Eldik, P van Gemmeren, J Van Nieuwkoop, I van Vulpen, M C van Woerden, M Vanadia, W Vandelli, R Vanguri, A Vaniachine, F Vannucci, G Vardanyan, R Vari, E W Varnes, T Varol, D Varouchas, A Vartapetian, K E Varvell, F Vazeille, T Vazquez Schroeder, J Veatch, L M Veloce, F Veloso, T Velz, S Veneziano, A Ventura, D Ventura, M Venturi, N Venturi, A Venturini, V Vercesi, M Verducci, W Verkerke, J C Vermeulen, A Vest, M C Vetterli, O Viazlo, I Vichou, T Vickey, O E Vickey Boeriu, G H A Viehhauser, S Viel, R Vigne, M Villa, M Villaplana Perez, E Vilucchi, M G Vincter, V B Vinogradov, I Vivarelli, S Vlachos, D Vladoiu, M Vlasak, M Vogel, P Vokac, G Volpi, M Volpi, H von der Schmitt, H von Radziewski, E von Toerne, V Vorobel, K Vorobev, M Vos, R Voss, J H Vossebeld, N Vranjes, M Vranjes Milosavljevic, V Vrba, M Vreeswijk, R Vuillermet, I Vukotic, Z Vykydal, P Wagner, W Wagner, H Wahlberg, S Wahrmund, J Wakabayashi, J Walder, R Walker, W Walkowiak, C Wang, F Wang, H Wang, H Wang, J Wang, J Wang, K Wang, R Wang, S M Wang, T Wang, T Wang, X Wang, C Wanotayaroj, A Warburton, C P Ward, D R Wardrope, A Washbrook, C Wasicki, P M Watkins, A T Watson, I J Watson, M F Watson, G Watts, S Watts, B M Waugh, S Webb, M S Weber, S W Weber, J S Webster, A R Weidberg, B Weinert, J Weingarten, C Weiser, H Weits, P S Wells, T Wenaus, T Wengler, S Wenig, N Wermes, M Werner, P Werner, M Wessels, J Wetter, K Whalen, A M Wharton, A White, M J White, R White, S White, D Whiteson, F J Wickens, W Wiedenmann, M Wielers, P Wienemann, C Wiglesworth, L A M Wiik-Fuchs, A Wildauer, H G Wilkens, H H Williams, S Williams, C Willis, S Willocq, A Wilson, J A Wilson, I Wingerter-Seez, F Winklmeier, B T Winter, M Wittgen, J Wittkowski, S J Wollstadt, M W Wolter, H Wolters, B K Wosiek, J Wotschack, M J Woudstra, K W Wozniak, M Wu, M Wu, S L Wu, X Wu, Y Wu, T R Wyatt, B M Wynne, S Xella, D Xu, L Xu, B Yabsley, S Yacoob, R Yakabe, M Yamada, D Yamaguchi, Y Yamaguchi, A Yamamoto, S Yamamoto, T Yamanaka, K Yamauchi, Y Yamazaki, Z Yan, H Yang, H Yang, Y Yang, W-M Yao, Y C Yap, Y Yasu, E Yatsenko, K H Yau Wong, J Ye, S Ye, I Yeletskikh, A L Yen, E Yildirim, K Yorita, R Yoshida, K Yoshihara, C Young, C J S Young, S Youssef, D R Yu, J Yu, J M Yu, J Yu, L Yuan, S P Y Yuen, A Yurkewicz, I Yusuff, B Zabinski, R Zaidan, A M Zaitsev, J Zalieckas, A Zaman, S Zambito, L Zanello, D Zanzi, C Zeitnitz, M Zeman, A Zemla, J C Zeng, Q Zeng, K Zengel, O Zenin, T Ženiš, D Zerwas, D Zhang, F Zhang, G Zhang, H Zhang, J Zhang, L Zhang, R Zhang, X Zhang, Z Zhang, X Zhao, Y Zhao, Z Zhao, A Zhemchugov, J Zhong, B Zhou, C Zhou, L Zhou, L Zhou, M Zhou, N Zhou, C G Zhu, H Zhu, J Zhu, Y Zhu, X Zhuang, K Zhukov, A Zibell, D Zieminska, N I Zimine, C Zimmermann, S Zimmermann, Z Zinonos, M Zinser, M Ziolkowski, L Živković, G Zobernig, A Zoccoli, M Zur Nedden, G Zurzolo, L Zwalinski
The reconstruction of the signal from hadrons and jets emerging from the proton-proton collisions at the Large Hadron Collider (LHC) and entering the ATLAS calorimeters is based on a three-dimensional topological clustering of individual calorimeter cell signals. The cluster formation follows cell signal-significance patterns generated by electromagnetic and hadronic showers. In this, the clustering algorithm implicitly performs a topological noise suppression by removing cells with insignificant signals which are not in close proximity to cells with significant signals...
2017: European Physical Journal. C, Particles and Fields
https://www.readbyqxmd.com/read/28943216/-the-third-dimension-of-the-face-aging-improvement-of-its-understanding
#11
S Garson, E Delay, R Sinna, B Cornette de Saint Cyr, F Taha
OBJECTIVES: Over the past 30 years, surface imaging has made tremendous progress. Surgical management has also been subject of numerous technical and strategic developments. For a better understanding of the curative strategies of face aging, the authors have put into perspective the three-dimensional data acquired up to date. METHOD: A review of the literature focused on the three-dimensional study of facial aging was carried out. RESULTS: Thanks to the precision of new surface acquisition systems and larger patient cohorts, our understanding of surfaces and volumes is now much more accurate...
September 21, 2017: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/28943039/three-dimensional-analysis-of-accuracy-of-component-positioning-in-total-knee-arthroplasty-with-patient-specific-and-conventional-instruments-a-randomized-controlled-trial
#12
Raf De Vloo, Pim Pellikaan, Aad Dhollander, Jos Vander Sloten
BACKGROUND: Component malalignment remains a major concern in total knee arthroplasty (TKA). Patient-specific guides (PSG) were developed to increase accuracy of bone resections and component placement, but available evidence is contradictory. We assessed the accuracy of 3D component placement in TKA with PSG compared to conventional surgery using virtual 3D bone models. METHODS: Fifty patients were randomly assigned to the PSG or conventional instrumentation group, 44 were finally analyzed...
September 21, 2017: Knee
https://www.readbyqxmd.com/read/28942976/unlocking-vendor-specific-tags-three-dimensional-printing-of-echocardiographic-data-sets
#13
Ahmed Hosny, Tao Shen, Alexander S Kuo, Dustin Long, Michael N Andrawes, Joshua D Dilley
No abstract text is available yet for this article.
September 1, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28942698/neuroimaging-findings-using-transfontanellar-ultrasound-in-newborns-with-microcephaly-a-possible-association-with-congenital-zika-virus-infection
#14
Ana Sofia França Cruz Ximenes, Pedro Pires, Heron Werner, Patricia Mello Jungmann, Epitácio Leite Rolim Filho, Etiene Pedrosa Andrade, Roberto Souza Lemos, Alberto Borges Peixoto, Mohammad Zare Mehrjardi, Gabriele Tonni, Edward Araujo Júnior
OBJECTIVE: To determine the main neuroimaging findings of microcephalic newborns with possible Zika virus (ZIKV) intrauterine infection using transfontanellar cranial ultrasound. METHODS: We performed a retrospective study to describe the main neuroimaging in newborns with microcephaly and possible association with congenital ZIKV infection. Microcephaly was defined in the postnatal period using transfontanellar cranial examination which was performed using both two- (2D) and three-dimensional (3D) ultrasound...
September 24, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28942609/custom-extracellular-matrix-cylinder-mitral-valve-in-a-pediatric-patient
#15
Clifford L Cua, Pace Johnston, Jill Harmon, Kathryn Shelton, Patrick I McConnell
Mitral valve construction using extracellular matrix (ECM) is a relatively new procedure. In this case, a 15-month-old boy with a history of severe mitral valve regurgitation secondary to endocarditis underwent mitral valve surgery. Mitral valve repair was not possible, and thus, a 17 mm extracellular matrix cylinder valve (ECM-CV) was constructed for valve replacement. The ECM-CV is clearly imaged using echocardiography, especially three-dimensional imaging, that helped define valve function. As the use of ECM for valve construction increases, echocardiography will play an essential role in evaluating the function and mechanics of these novel valves...
September 24, 2017: Echocardiography
https://www.readbyqxmd.com/read/28942230/investigation-of-zeolitic-imidazolate-frameworks-using-13-c-and-15-n-solid-state-nmr-spectroscopy
#16
Scott Sneddon, Jürgen Kahr, Angelica F Orsi, David J Price, Daniel M Dawson, Paul A Wright, Sharon E Ashbrook
Zeolitic imidazolate frameworks (ZIFs) are a subclass of metal-organic frameworks (MOFs) with extended three-dimensional networks of transition metal nodes (bridged by rigid imidazolate linkers), with potential applications in gas storage and separation, sensing and controlled delivery of drug molecules. Here, we investigate the use of (13)C and (15)N solid-state NMR spectroscopy to characterise the local structure and disorder in a variety of single- and dual-linker ZIFs. In most cases, a combination of a basic knowledge of chemical shifts typically observed in solution-state NMR spectroscopy and the use of dipolar dephasing NMR experiments to reveal information about quaternary carbon species are combined to enable spectral assignment...
September 9, 2017: Solid State Nuclear Magnetic Resonance
https://www.readbyqxmd.com/read/28942194/the-2-oxoglutarate-carrier-promotes-liver-cancer-by-sustaining-mitochondrial-gsh-despite-cholesterol-loading
#17
Anna Baulies, Joan Montero, Nuria Matías, Naroa Insausti, Oihana Terrones, Gorka Basañez, Carmen Vallejo, Laura Conde de La Rosa, Laura Martinez, David Robles, Albert Morales, Joaquin Abian, Montserrat Carrascal, Keigo Machida, Dinesh B U Kumar, Hidekazu Tsukamoto, Neil Kaplowitz, Carmen Garcia-Ruiz, José C Fernández-Checa
Cancer cells exhibit mitochondrial cholesterol (mt-cholesterol) accumulation, which contributes to cell death resistance by antagonizing mitochondrial outer membrane (MOM) permeabilization. Hepatocellular mt-cholesterol loading, however, promotes steatohepatitis, an advanced stage of chronic liver disease that precedes hepatocellular carcinoma (HCC), by depleting mitochondrial GSH (mGSH) due to a cholesterol-mediated impairment in mGSH transport. Whether and how HCC cells overcome the restriction of mGSH transport imposed by mt-cholesterol loading to support mGSH uptake remains unknown...
September 14, 2017: Redox Biology
https://www.readbyqxmd.com/read/28942083/intracellular-localization-of-pregnane-x-receptor-in-hepg2-cells-cultured-by-the-hanging-drop-method
#18
Kosuke Yokobori, Kaoru Kobayashi, Ikuko Azuma, Hidetaka Akita, Kan Chiba
Pregnane X receptor (PXR) is localized in the cytoplasm of liver cells, whereas it is localized in the nucleus of monolayer-cultured HepG2 cells. Since cultured cells are affected by the microenvironment in which they are grown, we studied the effect of three-dimensional (3D) culture on the localization of PXR in HepG2 cells using the hanging drop method. The results showed that PXR was retained in the cytoplasm of HepG2 cells and other human hepatocarcinoma cell lines (FLC5, FLC7 and Huh7) when they were cultured by the hanging drop method...
August 26, 2017: Drug Metabolism and Pharmacokinetics
https://www.readbyqxmd.com/read/28942003/inhalation-exposure-to-three-dimensional-printer-emissions-stimulates-acute-hypertension-and-microvascular-dysfunction
#19
A B Stefaniak, R F LeBouf, M G Duling, J Yi, A B Abukabda, C R McBride, T R Nurkiewicz
Fused deposition modeling (FDM™), or three-dimensional (3D) printing has become routine in industrial, occupational and domestic environments. We have recently reported that 3D printing emissions (3DPE) are complex mixtures, with a large ultrafine particulate matter component. We and others have reported that inhalation of xenobiotic particles in this size range is associated with an array of cardiovascular dysfunctions. Sprague-Dawley rats were exposed to 3DPE aerosols via nose-only exposure for ~3h. Twenty-four hours later, intravital microscopy was performed to assess microvascular function in the spinotrapezius muscle...
September 20, 2017: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/28941956/design-and-verification-of-a-simple-3d-dynamic-model-of-speed-skating-which-mimics-observed-forces-and-motions
#20
E van der Kruk, H E J Veeger, F C T van der Helm, A L Schwab
Advice about the optimal coordination pattern for an individual speed skater, could be addressed by simulation and optimization of a biomechanical speed skating model. But before getting to this optimization approach one needs a model that can reasonably match observed behaviour. Therefore, the objective of this study is to present a verified three dimensional inverse skater model with minimal complexity, which models the speed skating motion on the straights. The model simulates the upper body transverse translation of the skater together with the forces exerted by the skates on the ice...
September 14, 2017: Journal of Biomechanics
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