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https://www.readbyqxmd.com/read/28745525/balance-and-falls-in-acute-exacerbation-of-chronic-obstructive-pulmonary-disease-a-prospective-study
#1
Cristino C Oliveira, Annemarie L Lee, Jennifer McGinley, Gary P Anderson, Ross A Clark, Michelle Thompson, Sandy Clarke, Tamara Baker, Louis B Irving, Linda Denehy
Individuals with chronic obstructive pulmonary disease (COPD) have demonstrated balance impairment and a higher fall incidence. However, these have not been investigated in acute exacerbations of the disease (ECOPD). This study evaluates balance in patients during an ECOPD compared to stable COPD and healthy controls, and examines the fall incidence rate after hospitalisation due to ECOPD compared to individuals with stable COPD. Balance performance of 26 hospitalised patients with ECOPD was compared to 26 community-dwelling participants with stable COPD and 25 matched healthy controls...
July 26, 2017: COPD
https://www.readbyqxmd.com/read/28744048/effects-of-kinesio-taping-to-the-quadriceps-femoris-muscles-on-functions-of-elderly-women
#2
Eun Ja Kim, Kyoung Bo Lee
[Purpose] The purpose of this study is to investigate effects of kinesio taping to the quadriceps femoris on functions of elderly women. [Subjects and Methods] The subjects of this study were 22 elderly women with osteoarthritis, who were divided into two groups of a general exercise group 12 elderly and a kinesiology taping group 12 elderly. Two groups underwent a 30-min exercise for strengthening the lower limb muscles three times per week for four weeks. After the exercise, the kinesiology taping group was treated by the kinesio taping...
July 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28743821/the-effect-of-dietary-nitrate-supplementation-on-the-spatial-heterogeneity-of-quadriceps-deoxygenation-during-heavy-intensity-cycling
#3
Brynmor C Breese, David C Poole, Dai Okushima, Stephen J Bailey, Andrew M Jones, Narihiko Kondo, Tatsuro Amano, Shunsaku Koga
This study investigated the influence of dietary inorganic nitrate (NO3(-)) supplementation on pulmonary O2 uptake (V˙O2) and muscle deoxyhemoglobin/myoglobin (i.e. deoxy [Hb + Mb]) kinetics during submaximal cycling exercise. In a randomized, placebo-controlled, cross-over study, eight healthy and physically active male subjects completed two step cycle tests at a work rate equivalent to 50% of the difference between the gas exchange threshold and peak V˙O2 over separate 4-day supplementation periods with NO3(-)-rich (BR; providing 8...
July 2017: Physiological Reports
https://www.readbyqxmd.com/read/28739425/associations-of-isokinetic-and-isotonic-knee-strength-with-knee-function-and-activity-level-after-anterior-cruciate-ligament-reconstruction-a-prospective-cohort-study
#4
Yong-Hao Pua, Jia-Ying Ho, Suelyn Ai-Sim Chan, Shin-Jiun Khoo, Hwei-Chi Chong
BACKGROUND: Although isokinetic dynamometry often serves as a reference to assess the concurrent validity of weight-machine isotonic strength testing, it is unknown whether isokinetic knee strength is associated with knee function and activity level more strongly than isotonic knee strength in patients with an anterior cruciate ligament reconstruction (ACLR). This study aimed to compare the associations of isokinetic and isotonic knee strength with knee function and work-and-sports activity levels in patients with ACLR...
July 21, 2017: Knee
https://www.readbyqxmd.com/read/28736080/the-effect-of-ankle-foot-orthosis-alignment-on-walking-in-individuals-treated-for-traumatic-lower-extremity-injuries
#5
Starr E Brown, Elizabeth Russell Esposito, Jason M Wilken
Limb salvage surgeries are performed to treat a variety of lower limb pathologies and traumatic injuries. Individuals who have undergone limb salvage surgeries may require an ankle foot orthosis (AFO) to compensate for limb impairments and restore walking ability. Understanding the effects of AFO design parameters on gait biomechanics is important to refine AFO prescription criteria. In this study sagittal plane kinematic and kinetic data, muscle activity and alignment preference were examined as individuals treated for traumatic lower extremity injuries (N=12) walked over level ground with Plantarflexed (PF), Neutral, and Dorsiflexed (DF) aligned AFOs...
July 5, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28735881/recurrent-bilateral-quadriceps-tendon-rupture-due-to-indirect-trauma-in-a-patient-with-sickle-cell-trait-a-case-report
#6
Nathan Sherman, Rory Sandberg, Jolene Hardy
No abstract text is available yet for this article.
July 20, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28735802/correction-of-patellofemoral-malalignment-with-patellofemoral-arthroplasty
#7
Marco Valoroso, Mo Saffarini, Giuseppe La Barbera, Cécile Toanen, Gerjon Hannink, Luca Nover, David H Dejour
BACKGROUND: The goal of patellofemoral arthroplasty (PFA) is to replace damaged cartilage and correct underlying deformities to reduce pain and prevent maltracking. We aimed to determine how PFA modifies patellar height, tilt, and tibial tuberosity-trochlear groove (TT-TG) distance. The hypothesis was that PFA would correct trochlear dysplasia or extensor mechanism malalignment. METHODS: The authors prospectively studied a series of 16 patients (13 women and 3 men) aged 64...
July 8, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28735780/electromyographic-activity-of-the-vastus-intermedius-muscle-in-patients-with-stiff-knee-gait-after-stroke-a-retrospective-observational-study
#8
Davide Mazzoli, Erika Giannotti, Mario Manca, Maria Longhi, Paolo Prati, Michela Cosma, Giovanni Ferraresi, Monica Morelli, Paolo Zerbinati, Stefano Masiero, Andrea Merlo
Stiff-knee gait (SKG) in hemiplegic patients is often due to an inappropriate activity of the quadriceps femoris. However, there are no studies in literature addressing the vastus intermedius (VI) involvement in SKG. In this study, VI activity was analyzed in a sample of 46 chronic stroke patients with SKG, during spontaneous gait. VI activity was recorded by fine-wire electrodes inserted under ultrasound guidance then confirmed by electrical stimulation. The measured VI activity was compared to the normal reference pattern reported in literature and classified (e...
July 5, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28735354/transplantation-sites-for-human-and-murine-islets
#9
Rebecca A Stokes, Kim Cheng, Amit Lalwani, Michael M Swarbrick, Helen E Thomas, Thomas Loudovaris, Tom W Kay, Wayne J Hawthorne, Philip J O'Connell, Jenny E Gunton
AIMS/HYPOTHESIS: Beta cell replacement is a potential cure for type 1 diabetes. In humans, islet transplants are currently infused into the liver via the portal vein, although this site has disadvantages. Here, we investigated alternative transplantation sites for human and murine islets in recipient mice, comparing the portal vein with quadriceps muscle and kidney, liver and spleen capsules. METHODS: Murine islets were isolated from C57BL6/J mice and transplanted into syngeneic recipients...
July 22, 2017: Diabetologia
https://www.readbyqxmd.com/read/28730965/efficient-non-invasive-plasmid-dna-administration-into-tibialis-cranialis-muscle-of-little-mice
#10
C R Cecchi, E Higuti, E R Lima, D P Vieira, P L Squair, C N Peroni, P Bartolini
An alternative treatment for growth hormone deficiency based on hGH-DNA administration, followed by electro gene transfer, was investigated by injecting the plasmid into surgically exposed or non-exposed quadriceps or tibialis muscle of immunodeficient "little" mice. Previously optimized electrotransfer conditions were also improved via a new combination of high/low voltage pulses: after 3 days, serum hGH was determined. Both groups exhibited similar results: 5.0 ± 2.2 (SD) and 3.5 ± 0.9 ng hGH/ml (P>0...
July 21, 2017: Current Molecular Medicine
https://www.readbyqxmd.com/read/28729393/time-course-effects-of-aerobic-physical-training-in-the-prevention-of-cigarette-smoke-induced-copd
#11
Alessandra Choqueta Toledo-Arruda, Rodolfo Paula Vieira, Flavia Alessandra Guarnier, Camila Liyoko Suehiro, Agostinho Caleman-Neto, Clarice Rosa Olivo, Petra Mello Motta Arantes, Francine Maria Almeida, Fernanda Degobbi Tenorio Quirino Dos Santos Lopes, Ercy Mara Cipulo Ramos, Rubens Cecchini, Chin Jia Lin, Mílton A Martins
A previous study by our group showed that regular exercise training (ET) attenuated pulmonary injury in an experimental model of chronic exposure to cigarette smoke (CS) in mice, but the time-course effects of the mechanisms involved in this protection remain poorly understood. We evaluated the temporal effects of regular ET in an experimental model of chronic CS exposure. MaleC57BL/6 mice were divided into four groups: Control (sedentary+air), Exercise (aerobic training+air), Smoke (sedentary+smoke) and Smoke+Exercise (aerobic training+smoke)...
July 20, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28728611/effect-of-electrode-position-of-low-intensity-neuromuscular-electrical-stimulation-on-the-evoked-force-in-the-quadriceps-femoris-muscle
#12
Kohei Watanabe, Shuhei Kawade, Toshio Moritani
OBJECTIVE: The present study aimed to test the effect of the electrode position and inter-electrode distance on the evoked force by neuromuscular electrical stimulation (NMES) with a low current intensity and a single pair of electrodes. Knee extensor forces during NMES to quadriceps femoris muscles were compared among four different electrode configurations in seven healthy men. Electrodes were located at 10 cm proximal and 15 cm distal (P10-D15), 10 cm proximal and 10 cm distal (P10-D10), 5 cm proximal and 15 cm distal, and 5 cm proximal and 10 cm distal (P5-D10) to the center of the longitudinal axis of the quadriceps femoris muscles...
July 20, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28725437/towards-evidence-based-strength-training-a-comparison-of-muscle-forces-during-deadlifts-goodmornings-and-split-squats
#13
Florian Schellenberg, William R Taylor, Silvio Lorenzetti
BACKGROUND: To ensure an efficient and targeted adaptation with low injury risk during strength exercises, knowledge of the participant specific internal loading conditions is essential. The goal of this study was to calculate the lower limb muscles forces during the strength exercises deadlifts, goodmornings and splits squats by means of musculoskeletal simulation. METHODS: 11 participants were assessed performing 10 different variations of split squats by varying the step length as well as the maximal frontal tibia angle, and 13 participants were measured performing deadlift and goodmorning exercises...
2017: BMC Sports Science, Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28723717/localized-muscle-vibration-reverses-quadriceps-muscle-hypotrophy-and-improves-physical-function-a-clinical-and-electrophysiological-study
#14
Maria Grazia Benedetti, Gennaro Boccia, Lorenzo Cavazzuti, Elena Magnani, Elisabetta Mariani, Alberto Rainoldi, Roberto Casale
Quadriceps weakness has been associated with knee osteoarthritis (OA). High-frequency localized muscle vibration (LMV) has been proposed recently for quadriceps strengthening in patients with knee OA. The purpose of this study was (a) to investigate the clinical effectiveness of high-frequency LMV on quadriceps muscle in patients with knee OA and (b) to disentangle, by means of surface electromyography (sEMG), the underlying mechanism. Thirty patients, aged between 40 and 65 years, and clinically diagnosed with knee OA were included in this randomized, controlled, single-blinded pilot study...
July 18, 2017: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/28722815/influence-of-morphine-and-naloxone-on-pain-modulation-in-rheumatoid-arthritis-chronic-fatigue-syndrome-fibromyalgia-and-controls-a-double-blind-randomized-placebo-controlled-cross-over-study
#15
Linda Hermans, Jo Nijs, Patrick Calders, Luc De Clerck, Greta Moorkens, Guy Hans, Sofie Grosemans, Tine Roman De Mettelinge, Joanna Tuynman, Mira Meeus
BACKGROUND: Impaired pain inhibitory and enhanced pain facilitatory mechanisms are repeatedly reported in patients with central sensitization pain. However, the exact effects of frequently prescribed opioids on central pain modulation are still unknown. METHODS: A randomized, double-blind, placebo-controlled cross-over trial was carried out. Ten CFS/FM patients, 11 RA patients and 20 controls were randomly allocated to the experimental (10 mg morphine or 0.2 mg/ml Naloxone) and placebo (2 ml Aqua) group...
July 19, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28722298/development-of-a-bedside-viable-ultrasound-protocol-to-quantify-appendicular-lean-tissue-mass
#16
Michael T Paris, Benoit Lafleur, Joel A Dubin, Marina Mourtzakis
BACKGROUND: Ultrasound is a non-invasive and readily available tool that can be prospectively applied at the bedside to assess muscle mass in clinical settings. The four-site protocol, which images two anatomical sites on each quadriceps, may be a viable bedside method, but its ability to predict musculature has not been compared against whole-body reference methods. Our primary objectives were to (i) compare the four-site protocol's ability to predict appendicular lean tissue mass from dual-energy X-ray absorptiometry; (ii) optimize the predictability of the four-site protocol with additional anatomical muscle thicknesses and easily obtained covariates; and (iii) assess the ability of the optimized protocol to identify individuals with low lean tissue mass...
July 19, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28720481/knee-extension-and-flexion-strength-asymmetry-in-human-immunodeficiency-virus-positive-subjects-a-cross-sectional-study
#17
Vitor H F Oliveira, Susana L Wiechmann, Argéria M S Narciso, Rafael Deminice
BACKGROUND: Human Immunodeficiency Virus positive subjects present impairment in muscle function, neural activation, balance, and gait. In other populations, all of these factors have been associated with muscle strength asymmetry. OBJECTIVE: To investigate the existence of muscle strength asymmetry between dominant and non-dominant lower limbs and to determine the hamstrings-to-quadriceps strength ratio in Human Immunodeficiency Virus positive subjects. METHODS: In this cross-sectional study, 48 subjects were included (22 men and 26 women; mean age 44...
July 3, 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28718946/evidence-for-plical-support-of-the-patella
#18
Robert M Geraghty, Michelle Spear
There is a consensus that there is no overt anterior joint capsule in the knee. However, other anterior structures act in lieu of a joint capsule: the quadriceps tendon and patellar retinacular fibres. In the absence of a capsule, the synovium forms the suprapatellar pouch. Other synovial structures, the plicae, are more controversial. They are often described as embryonic remnants with no function, despite surrounding the patella. We aimed to identify plical anatomy and histology on cadaveric dissection and to examine their embryology using the human virtual embryo website...
July 18, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28718320/oral-prednisolone-for-4-days-does-not-increase-exercise-tolerance-in-men-with-copd
#19
S L Karlsson, V Backer, Nina Skavlan Godtfredsen
One of the primary objectives in management of chronic obstructive pulmonary disease (COPD) is preventing decrease in lung function and reducing the annual number of acute exacerbations of COPD (AECOPD). An oral course of systemic corticosteroids is a commonly used treatment in AECOPD. We hypothesize that this treatment also increases exercise performance and decreases muscle fatigue. In a randomized double-blinded, parallel, placebo-controlled trial, we investigated 14 men (8 on prednisolone 37.5 mg vs. 6 on placebo) with severe and very severe COPD...
January 1, 2017: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28717665/identification-of-an-alu-element-mediated-deletion-in-the-promoter-region-of-gne-in-siblings-with-gne-myopathy
#20
Jennifer Garland, Joshi Stephen, Bradley Class, Angela Gruber, Carla Ciccone, Aaron Poliak, Christina P Hayes, Vandana Singhal, Christina Slota, John Perreault, Ralitza Gavrilova, Joseph A Shrader, Prashant Chittiboina, Galen Joe, John Heiss, William A Gahl, Marjan Huizing, Nuria Carrillo, May Christine V Malicdan
BACKGROUND: GNE myopathy is a rare genetic disease characterized by progressive muscle atrophy and weakness. It is caused by biallelic mutations in the GNE gene that encodes for the bifunctional enzyme, uridine diphosphate (UDP)-N-acetylglucosamine (GlcNAc) 2-epimerase/N-acetylmannosamine (ManNAc) kinase. Typical characteristics of GNE myopathy include progressive myopathy, first involving anterior tibialis muscle and sparing the quadriceps, and rimmed vacuoles on muscle biopsy. Identifying biallelic mutations by sequencing of the GNE gene confirms the diagnosis of GNE myopathy...
July 2017: Molecular Genetics & Genomic Medicine
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