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https://www.readbyqxmd.com/read/29346717/anterior-cruciate-ligament-tear-induces-a-sustained-loss-of-muscle-fiber-force-production
#1
Jonathan P Gumucio, Kristoffer B Sugg, Elizabeth R Sibilsky Enselman, Alexis C Konja, Logan R Eckhardt, Asheesh Bedi, Christopher L Mendias
INTRODUCTION: Patients with anterior cruciate ligament (ACL) tears have persistent quadriceps strength deficits that are thought to be due to altered neurophysiological function. Our goal was to determine the changes in muscle fiber contractility independent of the ability of motor neurons to activate fibers. METHODS: We obtained quadriceps biopsies of patients undergoing ACL reconstruction, and additional biopsies one, two, and six months after surgery. Muscles fiber contractility was assessed in vitro, along with whole muscle strength testing...
January 18, 2018: Muscle & Nerve
https://www.readbyqxmd.com/read/29342246/associations-of-quadriceps-torque-properties-with-muscle-size-attenuation-and-intra-muscular-adipose-tissue-in-older-adults
#2
Andrew W Frank-Wilson, Didier Chalhoub, Pedro Figueiredo, Pálmi V Jónsson, Kristín Siggeirsdóttir, Sigurdur Sigurdsson, Gudny Eiriksdottir, Vilmundur Guðnason, Lenore Launer, Tamara B Harris
Background: Atrophy and fatty infiltration of muscle with aging are associated with fractures and falls, however, their direct associations with muscle function are not well described. It was hypothesized that participants with lower quadriceps muscle attenuation, area, and greater intra-muscular adipose tissue (IMAT) will exhibit slower rates of torque development (RTD) and lower peak knee extension torques. Methods: Data from 4842 participants (2041 men, 2801 women) from the Age Gene/Environment Susceptibility Reykjavik Study (mean age 76±0...
January 12, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29340537/bedside-ultrasound-is-a-practical-measurement-tool-for-assessing-muscle-mass
#3
Diogo Oliveira Toledo, Débora Carneiro de Lima E Silva, Dyaiane Marques Dos Santos, Branca Jardini de Freitas, Rogério Dib, Ricardo Luiz Cordioli, Evandro José de Almeida Figueiredo, Silvia Maria Fraga Piovacari, João Manoel Silva
OBJECTIVE: To evaluate the intra- and inter-reliability and the ease of measuring the quadriceps muscle thickness using bedside ultrasound. METHODS: This is a prospective, observational study. The assessment of quadriceps muscle thickness was performed at two reference points and was quantified using portable B-mode ultrasound in two healthy volunteers. For standardization of measurements and validation of image collections, the team was trained through theoretical and practical classes, with a 6-hour workload...
October 2017: Revista Brasileira de Terapia Intensiva
https://www.readbyqxmd.com/read/29338824/effects-of-preoperative-isokinetic-eccentric-training-and-whey-protein-isolate-supplement-on-quadriceps-strength-and-knee-function-in-patients-with-anterior-cruciate-ligament-rupture
#4
Xiao Yuan Zhang, Hong Shi Huang, Jie Yang, Yuan Yuan Yu, Dong Xia Zhang, Cui Qing Chang
Objective To explore the effect of preoperative isokinetic eccentric training with or not whey protein isolate supplement before operation on lower limb muscle strength and knee function in patients with anterior cruciate ligament (ACL) rupture. Methods A total of 22 male volunteers aged 18-40 years with ACL rupture were recruited in outpatient service. With randomized block design,subjects were randomly assigned to isokinetic eccentric training (IE) group and isokinetic eccentric training with whey protein isolate supplement (IE+WPI) group...
December 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/29334339/impact-of-spasticity-on-transfers-and-activities-of-daily-living-in-individuals-with-spinal-cord-injury
#5
Jacqueline Tibbett, Eva G Widerström-Noga, Christine K Thomas, Edelle C Field-Fote
CONTEXT/OBJECTIVE: For persons with spinal cord injury, spasticity commonly interferes with activities of daily living such as transfers. Electromyography can be used to objectively measure muscle spasms during transfers, but how electromyographic measures relate to the impact spasticity has on life, or to clinically-rated spasticity, is unclear. We aimed to characterize relationships among spasm duration and magnitude, impact of spasticity on daily life, and a clinical measure of extensor spasticity, as well as to determine reliability of the electromyographic measures...
January 15, 2018: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/29332757/activation-of-lower-limb-muscles-with-different-types-of-mount-in-hippotherapy
#6
Mariane Fernandes Ribeiro, Ana Paula Espindula, Domingos Emanuel Bevilacqua Júnior, Jéssica Aparecida Tolentino, Carolina Fioroni Ribeiro da Silva, Márcia Fernandes Araújo, Alex Abadio Ferreira, Vicente de Paula Antunes Teixeira
OBJECTIVES: To analyze muscle activation of lower limbs (LL) of subjects in hippotherapy sessions. METHODS: The study included 10 healthy subjects, five male and five female, with an average age of 24.03 (±4.06) years. Subjects underwent four hippotherapy sessions of 30 min with interval of one week, and each session was performed with a different type of mount material in the following order: 1st performed with saddle and feet in the stirrups (S1), 2nd with saddle and feet off the stirrups (S2), 3rd with blanket and feet off the stirrup (S3) and 4th with blanket and feet in the stirrups (S4)...
January 2018: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29332742/the-effects-of-dorso-lumbar-motion-restriction-on-emg-activity-of-selected-muscles-during-running
#7
Joseph J Morley, Edward Traum
The effects of restricting dorso-lumbar spine mobility on electromyographic activity of the erector spinae, quadriceps femoris, hamstrings and gastrocnemius muscles in runners was investigated. Thermoplastic casting material was fashioned into a rigid orthosis and used to restrict spinal motion during running. Volunteers ran on a treadmill at 2.78 m/sec, under normal conditions and with spinal motion restricted. Surface electromyographic data was collected during both sets of trials. Normal electromyographic data was also compared with previous authors to determine similarity with their electromyographic data...
January 2018: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29332207/skeletal-muscle-expression-of-p43-a-truncated-thyroid-hormone-receptor-%C3%AE-affects-lipid-composition-and-metabolism
#8
François Casas, Gilles Fouret, Jérome Lecomte, Fabienne Cortade, Laurence Pessemesse, Emilie Blanchet, Chantal Wrutniak-Cabello, Charles Coudray, Christine Feillet-Coudray
Thyroid hormone is a major regulator of metabolism and mitochondrial function. Thyroid hormone also affects reactions in almost all pathways of lipids metabolism and as such is considered as the main hormonal regulator of lipid biogenesis. The aim of this study was to explore the possible involvement of p43, a 43 Kda truncated form of the nuclear thyroid hormone receptor TRα1 which stimulates mitochondrial activity. Therefore, using mouse models overexpressing p43 in skeletal muscle (p43-Tg) or lacking p43 (p43-/-), we have investigated the lipid composition in quadriceps muscle and in mitochondria...
January 13, 2018: Journal of Bioenergetics and Biomembranes
https://www.readbyqxmd.com/read/29330345/a-computational-simulation-study-to-determine-the-biomechanical-influence-of-posterior-condylar-offset-and-tibial-slope-in-cruciate-retaining-total-knee-arthroplasty
#9
K-T Kang, Y-G Koh, J Son, O-R Kwon, J-S Lee, S K Kwon
OBJECTIVES: Posterior condylar offset (PCO) and posterior tibial slope (PTS) are critical factors in total knee arthroplasty (TKA). A computational simulation was performed to evaluate the biomechanical effect of PCO and PTS on cruciate retaining TKA. METHODS: We generated a subject-specific computational model followed by the development of ± 1 mm, ± 2 mm and ± 3 mm PCO models in the posterior direction, and -3°, 0°, 3° and 6° PTS models with each of the PCO models...
January 2018: Bone & Joint Research
https://www.readbyqxmd.com/read/29320561/%C3%AE-smooth-muscle-actin-is-not-a-marker-of-fibrogenic-cell-activity-in-skeletal-muscle-fibrosis
#10
Wanming Zhao, Xingyu Wang, Kai-Hui Sun, Lan Zhou
α-Smooth muscle actin (α-SMA) is used as a marker for a subset of activated fibrogenic cells, myofibroblasts, which are regarded as important effector cells of tissue fibrogenesis. We address whether α-SMA-expressing myofibroblasts are detectable in fibrotic muscles of mdx5cv mice, a mouse model for Duchenne muscular dystrophy (DMD), and whether the α-SMA expression correlates with the fibrogenic function of intramuscular fibrogenic cells. α-SMA immunostaining signal was not detected in collagen I (GFP)-expressing cells in fibrotic muscles of ColI-GFP/mdx5cv mice, but it was readily detected in smooth muscle cells lining intramuscular blood vessel walls...
2018: PloS One
https://www.readbyqxmd.com/read/29315579/muscle-molecular-adaptations-to-endurance-exercise-training-are-conditioned-by-glycogen-availability-a-proteomics-based-analysis-in-the-mcardle-mouse-model
#11
Carmen Fiuza-Luces, Alejandro Santos-Lozano, Francisco Llavero, Rocío Campo, Gisela Nogales-Gadea, Jorge Díez Bermejo, Carlos Balandrón, África González-Murillo, Joaquín Arenas, Miguel A Martín, Antoni L Andreu, Tomàs Pinós, Beatriz G Gálvez, Juan A López, Jesús Vázquez, José L Zugaza, Alejandro Lucia
McArdle disease is an inborn disorder of skeletal muscle glycogen metabolism that results in blockade of glycogen breakdown due to mutations in the myophosphorylase gene. We recently developed a mouse model carrying the homozygous p.R50X common human mutation (McArdle mouse), facilitating the study of how glycogen availability affects muscle molecular adaptations to endurance exercise training. Using quantitative differential analysis by liquid chromatography with tandem-mass spectrometry, we analysed the quadriceps muscle proteome of 16-week-old McArdle (n = 5) and wild-type (WT) (n = 4) mice previously subjected to 8-week moderate-intensity treadmill training or to an equivalent control (no training) period...
January 7, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29315348/knee-strength-ratios-in-competitive-female-athletes
#12
Jaroslaw Kabacinski, Michal Murawa, Krzysztof Mackala, Lechoslaw Bogdan Dworak
Knee strength ratios are related to the movement patterns, sport-specific training and knee injuries in athletes. The purpose of this study was to determine the ratios in the concentric isokinetic strength of the hamstrings and quadriceps and the isometric strength of the knee extensors. In female basketball players (n = 14) and female volleyball players (n = 12) were evaluated: the hamstrings to quadriceps peak torque ratio (H/Q) and side-to-side peak torque ratio (TR) for hamstrings and quadriceps; the ratio of the maximal bilateral strength to the summed maximal unilateral strength (B/U) and side-to-side maximal strength ratio (SR) for knee extensors...
2018: PloS One
https://www.readbyqxmd.com/read/29310344/polymyositis-with-elevated-serum-igg4-levels-and-abundant-igg4-plasma-cell-infiltration-a-case-report-and-literature-review
#13
Ryusuke Anan, Mitsuhiro Akiyama, Yuko Kaneko, Jun Kikuchi, Kazuko Suzuki, Shiro Matsubara, Tsutomu Takeuchi
INTRODUCTION: Polymyositis (PM) is a type of autoimmune, inflammatory myopathy. IgG4-related disease (IgG4-RD) is a recently recognized disease entity characterized by elevated serum IgG4 levels and IgG4 plasma-cell infiltration of various organs. However, several reports have described cases of other diseases that present with those features, suggesting the importance of careful differential diagnosis. Herein, we report the first case of PM with elevated serum IgG4 levels and IgG4 plasma cells in the muscles, mimicking IgG4-RD...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29308949/a-comparison-of-two-manual-physical-therapy-approaches-and-electrotherapy-modalities-for-patients-with-knee-osteoarthritis-a-randomized-three-arm-clinical-trial
#14
Ebru Kaya Mutlu, Ersin Ercin, Arzu Razak Ozdıncler, Nadir Ones
A broad spectrum of physical therapy exercise programs provides symptom relief and functional benefit for patients with knee OA. Manual physical therapy, including tailored exercise programs provide relatively higher level benefit that persists to one year. It is currently unknown if there are important differences in the effects of different manual physical therapy techniques for patients with knee OA and there are virtually no studies comparing manual physical therapy and electrotherapy modalities. The aim of the study was to compare long-term results between three treatment groups (mobilization with movements [MWMs], passive joint mobilization [PJM], and electrotherapy) to determine which treatment is most effective in patients with knee OA...
January 8, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29303130/quadriceps-strength-and-anterior-knee-pain-following-tibia-intramedullary-nailing-any-clinical-relationship
#15
O Esan, A O Ojoawo, I C Ikem
INTRODUCTION: Anterior knee pain can be chronic sequelae of intramedullary nailing of the tibia. Several causes have been identified; no single reason can fully explain the occurrence. We, therefore, set out to find the rate of anterior knee pain in our practice and if any relationship exists between the anterior knee pain and extensor muscle strength. METHODOLOGY: A total of 72 knees in 36 patients with no prior history of knee pain, but had unilateral tibiofibular fracture, who had internal fixation with interlocking intramedullary nailing done and were followed up for at least 1 year were recruited into the study...
November 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29299474/improvement-in-hamstring-and-quadriceps-muscle-strength-following-cruciate-retaining-single-radius-total-knee-arthroplasty
#16
Jennifer Kurowicki, Anton Khlopas, Assem A Sultan, Nipun Sodhi, Linsen T Samuel, Morad Chughtai, Martin Roche, Peter M Bonutti, Michael A Mont
Background: The ability to reach full functional capacity following total knee arthroplasty (TKA) is reliant on the strength of the quadriceps and hamstring muscles. Weakness of these muscles can persist anywhere from 1 to 3 years post-operatively. There remains considerable controversy as to what factors influence restoration of muscle strength after TKA. Implant designs have been implicated in the ability of patients to recover. Currently there is a paucity of literature available describing the influence of patient characteristics, surgical factors, and clinical outcomes on quadriceps and hamstring muscle strength following TKA with a cruciate-retaining, single radius (SR) implant...
December 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/29299224/the-effectiveness-of-functional-electrical-stimulation-fes-in-on-off-mode-for-enhancing-the-cycling-performance-of-team-phoenix-at-2016-cybathlon
#17
Kenry Wc Leung, Raymond Ky Tong, Xiaojun Wang, Ginny Ty Lee, Peter Mk Pang, H W Wai, H C Leung
In this study we designed a Functional Electrical Stimulation (FES) trike for a female subject with spinal cord injury to exercise her lower limbs and improve her lower limb muscle condition for attending the 2016 Cybathlon FES bike competition. Our FES pilot was the only female participant, in the FES cycling competition and she rode for Team Phoenix from the Chinese University of Hong Kong. Due to the weakness of muscles in the lower limb of the subject, and due to scoliosis over her thoracolumbar aéra, the mechanical structure of the trike had to be tailor-made to ensure she sat on the bike in a safe and secure position...
December 5, 2017: European Journal of Translational Myology
https://www.readbyqxmd.com/read/29299223/participation-to-the-first-cybathlon-an-overview-of-the-freewheels-team-fes-cycling-solution
#18
Benoît Sijobert, Charles Fattal, Anne Daubigney, Christine Azevedo-Coste
This article is a contribution to a special issue aiming at collecting data and documenting the different specificities of the teams which participated into Cybathlon 2016 FES-bike discipline. Our team prepared one paraplegic pilot over one year and developed a FES-cycling device based on existing commercial products. Our pilot (47 y.o, spinal cord lesion T3 AIS A since year 1995) was qualified for the final race and finished in 6th position over 12 participants in the discipline, covering a total distance of 750m at an average speed of 5...
December 5, 2017: European Journal of Translational Myology
https://www.readbyqxmd.com/read/29290379/relationships-between-muscle-mass-intramuscular-adipose-and-fibrous-tissues-of-the-quadriceps-and-gait-independence-in-chronic-stroke-survivors-a-cross-sectional-study
#19
Naoki Akazawa, Kazuhiro Harada, Naomi Okawa, Kimiyuki Tamura, Atsushi Hayase, Hideki Moriyama
OBJECTIVE: To examine the relationships between muscle mass, intramuscular adipose and fibrous tissues of the quadriceps, and gait independence in chronic stroke survivors. DESIGN: Cross-sectional study. SETTING: Hospital-based research. PARTICIPANTS: Seventeen chronic stroke survivors who were unable to walk independently (non-independent walker group) and 11 chronic stroke survivors who were able to walk independently (independent walker group) participated in this study...
December 1, 2017: Physiotherapy
https://www.readbyqxmd.com/read/29287785/evaluation-of-muscle-activity-just-after-straight-leg-raising-exercise-by-using-18fdg-pet
#20
Hiroyuki Shiozawa, Takashi Ohsawa, Yoshito Tsushima, Tetsuya Higuchi, Kenji Takagishi, Hirotaka Chikuda
BACKGROUND: Exercise therapy is one of the recognized treatment methods for knee osteoarthritis (KOA). One such exercise technique, straight leg raising (SLR), is widely known as a home exercise method for strengthening the quadriceps femoris muscle. However, whether this exercise truly strengthens the quadriceps is not known. The objective of the present study was to investigate which lower limb muscle is stimulated and shows increased activity with SLR. METHODS: A total of 14 lower limbs in seven healthy adult male volunteers (mean age: 31...
December 26, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
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