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https://www.readbyqxmd.com/read/29428417/juicebox-js-provides-a-cloud-based-visualization-system-for-hi-c-data
#1
James T Robinson, Douglass Turner, Neva C Durand, Helga Thorvaldsdóttir, Jill P Mesirov, Erez Lieberman Aiden
Contact mapping experiments such as Hi-C explore how genomes fold in 3D. Here, we introduce Juicebox.js, a cloud-based web application for exploring the resulting datasets. Like the original Juicebox application, Juicebox.js allows users to zoom in and out of such datasets using an interface similar to Google Earth. Juicebox.js also has many features designed to facilitate data reproducibility and sharing. Furthermore, Juicebox.js encodes the exact state of the browser in a shareable URL. Creating a public browser for a new Hi-C dataset does not require coding and can be accomplished in under a minute...
February 5, 2018: Cell Systems
https://www.readbyqxmd.com/read/29407657/modeling-of-passengers-safety-perception-for-buses-on-mountainous-roads
#2
Hooi Ling Khoo, Muaid Ahmed
This study had developed a passenger safety perception model specifically for buses taking into consideration the various factors, namely driver characteristics, environmental conditions, and bus characteristics using Bayesian Network. The behaviour of bus driver is observed through the bus motion profile, measured in longitudinal, lateral, and vertical accelerations. The road geometry is recorded using GPS and is computed with the aid of the Google map while the perceived bus safety is rated by the passengers in the bus in real time...
January 31, 2018: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29398924/implementing-a-geographical-information-system-to-assess-endemic-fluoride-areas-in-lamphun-thailand
#3
Nonthaphat Theerawasttanasiri, Surasak Taneepanichskul, Wichain Pingchai, Yuwaree Nimchareon, Sangworn Sriwichai
Introduction: Many studies have shown that fluoride can cross the placenta and that exposure to high fluoride during pregnancy may result in premature birth and/or a low birth weight. Lamphun is one of six provinces in Thailand where natural water fluoride (WF) concentrations >10.0 mg/L were found, and it was also found that >50% of households used water with high fluoride levels. Nevertheless, geographical information system (GIS) and maps of endemic fluoride areas are lacking...
2018: Risk Management and Healthcare Policy
https://www.readbyqxmd.com/read/29396220/access-to-emergency-hospital-care-provided-by-the-public-sector-in-sub-saharan-africa-in-2015-a-geocoded-inventory-and-spatial-analysis
#4
Paul O Ouma, Joseph Maina, Pamela N Thuranira, Peter M Macharia, Victor A Alegana, Mike English, Emelda A Okiro, Robert W Snow
BACKGROUND: Timely access to emergency care can substantially reduce mortality. International benchmarks for access to emergency hospital care have been established to guide ambitions for universal health care by 2030. However, no Pan-African database of where hospitals are located exists; therefore, we aimed to complete a geocoded inventory of hospital services in Africa in relation to how populations might access these services in 2015, with focus on women of child bearing age. METHODS: We assembled a geocoded inventory of public hospitals across 48 countries and islands of sub-Saharan Africa, including Zanzibar, using data from various sources...
January 25, 2018: Lancet Global Health
https://www.readbyqxmd.com/read/29379836/cost-effectiveness-of-colorectal-cancer-screening-and-treatment-methods-mapping-of-systematic-reviews
#5
REVIEW
Hossein Mashhadi Abdolahi, Ali Sarabi Asiabar, Saber Azami-Aghdash, Fatemeh Pournaghi-Azar, Aziz Rezapour
Objective: Due to extensive literature on colorectal cancer and their heterogeneous results, this study aimed to summarize the systematic reviews which review the cost-effectiveness studies on different aspects of colorectal cancer. Methods: The required data were collected by searching the following key words according to MeSH: "colorectal cancer," "colorectal oncology," "colorectal carcinoma," "colorectal neoplasm," "colorectal tumors," "cost-effectiveness," "systematic review," and "meta-analysis...
January 2018: Asia-Pacific Journal of Oncology Nursing
https://www.readbyqxmd.com/read/29372085/distribution-of-trauma-care-facilities-in-oman-in-relation-to-high-incidence-road-traffic-injury-sites-pilot-study
#6
Sara M Al-Kindi, Ahmed A Naiem, Kadhim M Taqi, Najla M Al-Gheiti, Ikhtiyar S Al-Toobi, Nasra Q Al-Busaidi, Ahmed Z Al-Harthy, Alaa M Taqi, Sharif A Ba-Alawi, Hani A Al-Qadhi
Objectives: Road traffic injuries (RTIs) are considered a major public health problem worldwide. In Oman, high numbers of RTIs and RTI-related deaths are frequently registered. This study aimed to evaluate the distribution of trauma care facilities in Oman with regards to their proximity to RTI-prevalent areas. Methods: This descriptive pilot study analysed RTI data recorded in the national Royal Oman Police registry from January to December 2014. The distribution of trauma care facilities was analysed by calculating distances between areas of peak RTI incidence and the closest trauma centre using Google Earth and Google Maps software (Google Inc...
November 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29359958/effect-of-resveratrol-on-blood-pressure-a-systematic-review-and-meta-analysis-of-randomized-controlled-clinical-trials
#7
Federica Fogacci, Giuliano Tocci, Vivianne Presta, Andrea Fratter, Claudio Borghi, Arrigo F G Cicero
INTRODUCTION: Results of previous clinical trials evaluating the effect of resveratrol supplementation on blood pressure (BP) are controversial. PURPOSE: We aimed to assess the impact of resveratrol on BP through systematic review of literature and meta-analysis of available randomized, controlled clinical trials (RCTs). METHODS: Literature search included SCOPUS, PubMed-Medline, ISI Web of Science and Google Scholar databases up to 17th October 2017 to identify RCTs investigating the impact of resveratrol on BP...
January 23, 2018: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29358567/multi-frame-super-resolution-of-gaofen-4-remote-sensing-images
#8
Jieping Xu, Yonghui Liang, Jin Liu, Zongfu Huang
Gaofen-4 is China's first geosynchronous orbit high-definition optical imaging satellite with extremely high temporal resolution. The features of staring imaging and high temporal resolution enable the super-resolution of multiple images of the same scene. In this paper, we propose a super-resolution (SR) technique to reconstruct a higher-resolution image from multiple low-resolution (LR) satellite images. The method first performs image registration in both the spatial and range domains. Then the point spread function (PSF) of LR images is parameterized by a Gaussian function and estimated by a blind deconvolution algorithm based on the maximum a posteriori (MAP)...
September 18, 2017: Sensors
https://www.readbyqxmd.com/read/29351899/web-based-survey-application-to-collect-contextually-relevant-geographic-data-with-exposure-times-application-development-and-feasibility-testing
#9
Abby Rudolph, Karin Tobin, Jonathan Rudolph, Carl Latkin
BACKGROUND: Although studies that characterize the risk environment by linking contextual factors with individual-level data have advanced infectious disease and substance use research, there are opportunities to refine how we define relevant neighborhood exposures; this can in turn reduce the potential for exposure misclassification. For example, for those who do not inject at home, injection risk behaviors may be more influenced by the environment where they inject than where they live...
January 19, 2018: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/29351802/objectively-measured-active-transportation-to-school-and-other-destinations-among-10-13%C3%A2-year-olds
#10
Gillian C Williams, Michael M Borghese, Ian Janssen
BACKGROUND: Descriptive data on active transportation in children focuses on the trip to school and has relied on subjective reports. The purpose of this study was to use objective measures to describe total active transportation and active transportation to common destinations within children. METHODS: This was a descriptive study of 388 children aged 10-13 years from Kingston, Ontario, Canada. Participants wore a Garmin GPS watch during waking hours for seven days...
January 19, 2018: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/29340269/examining-relationships-between-perceptions-and-objective-assessments-of-neighborhood-environment-and-sedentary-time-data-from-the-washington-d-c-cardiovascular-health-and-needs-assessment
#11
Chaarushi Ahuja, Colby Ayers, Jacob Hartz, Joel Adu-Brimpong, Samantha Thomas, Valerie Mitchell, Marlene Peters-Lawrence, Dana Sampson, Alyssa T Brooks, Gwenyth Wallen, Allan Johnson, Lennox Graham, Avis Graham, Joshua Rivers, Leah Yingling, Tiffany M Powell-Wiley
Sedentary time (ST) and neighborhood environment (NE) are predictors of cardiovascular (CV) health. However, little is known about ST's relationship with NE. We examined associations of perceived and objective NE with ST in the predominantly African American faith-based population of the Washington, D.C. CV Health and Needs Assessment. After using community-based research principles, participants reported NE perceptions, including sidewalks, recreational areas, and crime presence. Factor analysis was conducted to explore pertinent constructs; factor sums were created and combined as Total Perception Score (TPS) (higher score = more favorable perception)...
March 2018: Preventive Medicine Reports
https://www.readbyqxmd.com/read/29320477/a-global-map-of-travel-time-to-cities-to-assess-inequalities-in-accessibility-in-2015
#12
D J Weiss, A Nelson, H S Gibson, W Temperley, S Peedell, A Lieber, M Hancher, E Poyart, S Belchior, N Fullman, B Mappin, U Dalrymple, J Rozier, T C D Lucas, R E Howes, L S Tusting, S Y Kang, E Cameron, D Bisanzio, K E Battle, S Bhatt, P W Gething
The economic and man-made resources that sustain human wellbeing are not distributed evenly across the world, but are instead heavily concentrated in cities. Poor access to opportunities and services offered by urban centres (a function of distance, transport infrastructure, and the spatial distribution of cities) is a major barrier to improved livelihoods and overall development. Advancing accessibility worldwide underpins the equity agenda of 'leaving no one behind' established by the Sustainable Development Goals of the United Nations...
January 10, 2018: Nature
https://www.readbyqxmd.com/read/29298131/a-systematic-review-of-p53-regulation-of-oxidative-stress-in-skeletal-muscle
#13
Kaitlyn Beyfuss, David A Hood
BACKGROUND: p53 is a tumor suppressor protein involved in regulating a wide array of signaling pathways. The role of p53 in the cell is determined by the type of imposed oxidative stress, its intensity and duration. The last decade of research has unravelled a dual nature in the function of p53 in mediating the oxidative stress burden. However, this is dependent on the specific properties of the applied stress and thus requires further analysis. METHODS: A systematic review was performed following an electronic search of Pubmed, Google Scholar, and ScienceDirect databases...
January 3, 2018: Redox Report: Communications in Free Radical Research
https://www.readbyqxmd.com/read/29277900/brain-maps-4-0-structure-of-the-rat-brain-an-open-access-atlas-with-global-nervous-system-nomenclature-ontology-and-flatmaps
#14
Larry W Swanson
The fourth edition (following editions in 1992, 1998, 2004) of Brain maps: structure of the rat brain is presented here as an open access internet resource for the neuroscience community. One new feature is a set of 10 hierarchical nomenclature tables that define and describe all parts of the rat nervous system within the framework of a strictly topographic system devised previously for the human nervous system. These tables constitute a global ontology for knowledge management systems dealing with neural circuitry...
December 26, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/29276627/patient-and-public-involvement-in-health-literacy-interventions-a-mapping-review
#15
Stephanie Howard Wilsher, Julii Brainard, Yoon Loke, Charlotte Salter
Plain English summary: If people can read, understand and act on health information to better their health and reduce illness, they are thought to have "adequate" health literacy. Poor health literacy can mean people are less able to access health care and manage their health. Health literacy tends to worsen as adults get older, and is especially poor in adults age 65 and over. Ideally, health literacy interventions target people before age 65, to establish good skills and habits before people have many health problems associated with ageing...
2017: Research Involvement and Engagement
https://www.readbyqxmd.com/read/29233800/participant-centric-initiatives-and-medical-research-scoping-review-protocol
#16
Victoria Coathup, Nao Hamakawa, Teresa Finlay, Jessica Bell, Jane Kaye, Kazuto Kato
BACKGROUND: Significant advances in digital technologies have meant that health care data can be collected, stored, transferred, and analyzed for research purposes more easily than ever before. Participant-centric initiatives (PCI) are defined as "tools, programs, and projects that empower participants to engage in the research process" using digital technologies and have the potential to provide a number of benefits to both participants and researchers, including the promotion of public trust in medical research, improved quality of research, increased recruitment and retention, and improved health care delivery...
December 12, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/29223936/-relationship-between-crowding-and-community-acquired-skin-and-soft-tissues-infections
#17
Marcelo A Beltrán, Horacio J García Del Corro, Mónica Couso, María D Gallo, Antonio Lettieri, Patricia V Barna
The association of the spread of community infections with poverty and overcrowding is well known. In our hospital, located in José C. Paz, we assist sporadic cases of post-cesarean infections caused by community acquired methicillin-resistant Staphylococcus aureus (CaMRSA). In a prospective study of families treated at our hospital, we investigated the relationship between a history of skin and soft tissue infections (SSTI) and extreme overcrowding defined as households with unsatisfied basic needs type 3 (NBI 3)...
2017: Medicina
https://www.readbyqxmd.com/read/29220396/improved-approach-for-electric-vehicle-rapid-charging-station-placement-and-sizing-using-google-maps-and-binary-lightning-search-algorithm
#18
Md Mainul Islam, Hussain Shareef, Azah Mohamed
The electric vehicle (EV) is considered a premium solution to global warming and various types of pollution. Nonetheless, a key concern is the recharging of EV batteries. Therefore, this study proposes a novel approach that considers the costs of transportation loss, buildup, and substation energy loss and that incorporates harmonic power loss into optimal rapid charging station (RCS) planning. A novel optimization technique, called binary lightning search algorithm (BLSA), is proposed to solve the optimization problem...
2017: PloS One
https://www.readbyqxmd.com/read/29211150/-use-of-google-maps-for-geocoding-data-from-the-mortality-information-system-in-rio-de-janeiro-municipality-brazil-2010-2012
#19
Ismael Henrique da Silveira, Beatriz Fátima Alves de Oliveira, Washington Leite Junger
OBJECTIVE: to describe the results of the application of a low cost procedure, using free software, for geocoding data from the Mortality Information System (SIM), in the municipality of Rio de Janeiro. METHODS: descriptive study using Google Maps database for geocoding deaths data recorded at SIM, occurred from 2010 to 2012, in Rio de Janeiro; the study was carried out in three stages, (i) standardization of addresses, (ii) geocoding by Google Maps, and (iii) manual intervention...
October 2017: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/29202866/tracheostomy-decannulation-methods-and-procedures-in-adults-a-systematic-scoping-review-protocol
#20
John Kutsukutsa, Tivani Phosa Mashamba-Thompson, Yougan Saman
BACKGROUND: The indications for and the number of tracheostomy procedures has increased with advances in critical care. Studies are indicating likely continued increase in number of tracheostomies. Despite the important benefits of a tracheostomy, its presence is associated with adverse health complications and lowered patient quality of life. Hence, it must be decannulated as soon as it is no longer indicated in a safe and effective manner. There is, however, no agreed universal standard of care for tracheostomy decannulation (TD) in adults...
December 4, 2017: Systematic Reviews
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