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https://www.readbyqxmd.com/read/28722536/travel-burden-associated-with-granulocyte-colony-stimulating-factor-administration-in-a-medicare-aged-population-a-geospatial-analysis
#1
J Mark Stephens, Mark Bensink, Charles Bowers, Christopher S Hollenbeak
OBJECTIVE: Prophylaxis with granulocyte colony-stimulating factors (G-CSFs) is recommended for patients receiving myelosuppressive chemotherapy regimens with a high risk of febrile neutropenia (FN). G-CSFs should be administered starting the day after chemotherapy, necessitating return trips to the oncology clinic at the end of each cycle. We examined the travel burden related to prophylactic G-CSF injections after chemotherapy in the United States (US). METHODS: We used 2012-2014 Medicare claims data to identify a national cohort of beneficiaries age 65+ with non-myeloid cancers who received both chemotherapy and prophylactic G-CSFs...
July 19, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28684524/citywide-effects-of-high-occupancy-vehicle-restrictions-evidence-from-three-in-one-in-jakarta
#2
Rema Hanna, Gabriel Kreindler, Benjamin A Olken
Widespread use of single-occupancy cars often leads to traffic congestion. Using anonymized traffic speed data from Android phones collected through Google Maps, we investigated whether high-occupancy vehicle (HOV) policies can combat congestion. We studied Jakarta's "three-in-one" policy, which required all private cars on two major roads to carry at least three passengers during peak hours. After the policy was abruptly abandoned in April 2016, delays rose from 2.1 to 3.1 minutes per kilometer (min/km) in the morning peak and from 2...
July 7, 2017: Science
https://www.readbyqxmd.com/read/28646857/overview-of-post-discharge-predictors-for-psychiatric-re-hospitalisations-a-systematic-review-of-the-literature
#3
R Sfetcu, S Musat, P Haaramo, M Ciutan, G Scintee, C Vladescu, K Wahlbeck, H Katschnig
BACKGROUND: High levels of hospital readmission (rehospitalisation rates) is widely used as indicator of a poor quality of care. This is sometimes also referred to as recidivism or heavy utilization. Previous studies have examined a number of factors likely to influence readmission, although a systematic review of research on post-discharge factors and readmissions has not been conducted so far. The main objective of this review was to identify frequently reported post-discharge factors and their effects on readmission rates...
June 24, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28628586/building-a-pediatric-oral-health-training-curriculum-for-community-health-workers
#4
Molly Martin, William Frese, Christie Lumsden, Anna Sandoval
OBJECTIVES: Community health workers (CHWs) are a promising approach to oral health promotion in high-risk populations. This article describes the process of creating a pediatric oral health CHW training curriculum. DESIGN: Existing curricula were identified through outreach efforts to experts in the oral health and CHW fields, as well as PubMed and Google searches. After coding basic information, curricula were mapped to define oral health domains. Then group discussion was employed to determine final curriculum contents...
June 16, 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28626426/potential-of-central-eastern-and-western-africa-medicinal-plants-for-cancer-therapy-spotlight-on-resistant-cells-and-molecular-targets
#5
REVIEW
Armelle T Mbaveng, Victor Kuete, Thomas Efferth
Cancer remains a major health hurdle worldwide and has moved from the third leading cause of death in the year 1990 to second place after cardiovascular disease since 2013. Chemotherapy is one of the most widely used treatment modes; however, its efficiency is limited due to the resistance of cancer cells to cytotoxic agents. The present overview deals with the potential of the flora of Central, Eastern and Western African (CEWA) regions as resource for anticancer drug discovery. It also reviews the molecular targets of phytochemicals of these plants such as ABC transporters, namely P-glycoprotein (P-gp), multi drug-resistance-related proteins (MRPs), breast cancer resistance protein (BCRP, ABCG2) as well as the epidermal growth factor receptor (EGFR/ErbB-1/HER1), human tumor suppressor protein p53, caspases, mitochondria, angiogenesis, and components of MAP kinase signaling pathways...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28608393/the-impact-of-the-use-of-intraoperative-radiotherapy-on-costs-travel-time-and-distance-for-women-with-breast-cancer-in-the-mexico-city-metropolitan-area
#6
Juan Enrique Bargallo-Rocha, Enrique Soto-Perez-de-Celis, Francisco Javier Picó-Guzmán, Carlos Eduardo Quintero-Rodríguez, David Almog, Gabriel Santiago-Concha, Christian Haydee Flores-Balcazar, Jaime Corona, Rafael Vazquez-Romo, Cynthia Villarreal-Garza, Alejandro Mohar
BACKGROUND AND OBJECTIVES: The low availability and poor access to external beam radiotherapy (EBRT) in developing countries makes it hard for women with breast cancer to receive breast conservation. We studied the effect of providing intraoperative radiotherapy (IORT) on the travel time, distance, and costs of in the Mexico City Metropolitan Area (MCMA). METHODS: Sixty-nine patients treated between January 2013 and September 2014 were analyzed. Travel distance and transit time was calculated using Google Maps...
June 12, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28602837/a-review-on-epidemiology-global-prevalence-and-economical-losses-of-fasciolosis-in-ruminants
#7
REVIEW
Khalid Mehmood, Hui Zhang, Ahmad Jawad Sabir, Rao Zahid Abbas, Muhammad Ijaz, Aneela Zameer Durrani, Muhammad Hassan Saleem, Mujeeb Ur Rehman, Muhammad Kashif Iqbal, Yajing Wang, Hafiz Ishfaq Ahmad, Tariq Abbas, Riaz Hussain, Muhammad Taslim Ghori, Sadaqat Ali, Aman Ullah Khan, Jiakui Li
Fasciolosis is an important plant borne trematode zoonosis in ruminants caused by the Fasciola hepatica and Fasciola gigentica, It is classified as a neglected tropical disease and found in more than 50 countries especially where sheep and cattle are reared. Fasciolosis is a serious animal health problems in many rural and urban areas of world, causing significant financial losses due to decrease in production and viscera condemnation in animals. Accurate diagnosis of fasciolosis is always remained a challenging task for the field practitioners...
June 7, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28587186/measuring-neighborhood-walkable-environments-a-comparison-of-three-approaches
#8
Yen-Cheng Chiang, William Sullivan, Linda Larsen
Multiple studies have revealed the impact of walkable environments on physical activity. Scholars attach considerable importance to leisure and health-related walking. Recent studies have used Google Street View as an instrument to assess city streets and walkable environments; however, no study has compared the validity of Google Street View assessments of walkable environment attributes to assessments made by local residents and compiled from field visits. In this study, we involved nearby residents and compared the extent to which Google Street View assessments of the walkable environment correlated with assessments from local residents and with field visits...
June 3, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28578585/high-resolution-air-pollution-mapping-with-google-street-view-cars-exploiting-big-data
#9
Joshua S Apte, Kyle P Messier, Shahzad Gani, Michael Brauer, Thomas W Kirchstetter, Melissa M Lunden, Julian D Marshall, Christopher J Portier, Roel C H Vermeulen, Steven P Hamburg
Air pollution affects billions of people worldwide, yet ambient pollution measurements are limited for much of the world. Urban air pollution concentrations vary sharply over short distances (≪1 km) owing to unevenly distributed emission sources, dilution, and physicochemical transformations. Accordingly, even where present, conventional fixed-site pollution monitoring methods lack the spatial resolution needed to characterize heterogeneous human exposures and localized pollution hotspots. Here, we demonstrate a measurement approach to reveal urban air pollution patterns at 4-5 orders of magnitude greater spatial precision than possible with current central-site ambient monitoring...
June 5, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28551861/determinants-of-clinic-absenteeism-a-novel-method-of-examining-distance-from-clinic-and-transportation
#10
Ryan W Dobbs, Neha R Malhotra, Brandon M Caldwell, Raymond Rojas, Daniel M Moreira, Michael R Abern
Delayed treatment and non-adherence are associated with inferior prostate cancer (CaP) outcomes. Missed clinic appointments (MA) are one form of non-adherence that may be preventable. We conducted a retrospective cohort study of 1341 scheduled clinic encounters for men referred to an academic urology clinic for evaluation of known or suspected CaP. Driving distance and public transit times were calculated using a Google Distance Matrix API algorithm. Zip code level data regarding socioeconomic status was obtained from the 2013 American Community Survey...
May 27, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28547345/where-are-adults-active-an-examination-of-physical-activity-locations-using-gps-in-five-us-cities
#11
Katelyn M Holliday, Annie Green Howard, Michael Emch, Daniel A Rodríguez, Wayne D Rosamond, Kelly R Evenson
Increasing physical activity (PA) at the population level requires appropriately targeting intervention development. Identifying the locations in which participants with various sociodemographic, body weight, and geographic characteristics tend to engage in varying intensities of PA as well as locations these populations underutilize for PA may facilitate this process. A visual location-coding protocol was developed and implemented in Google Fusion Tables and Maps using data from participants (N = 223, age 18-85) in five states...
May 25, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28536914/inter-comparison-of-remote-sensing-sensing-based-shoreline-mapping-techniques-at-different-coastal-stretches-of-india
#12
Swathy Sunder, Raaj Ramsankaran, Balaji Ramakrishnan
Many techniques are available for detection of shorelines from multispectral satellite imagery, but the choice of a certain technique for a particular study area can be tough. Hence, for the first time in literature, an inter-comparison of the most widely used shoreline mapping techniques such as Normalized Difference Water Index (NDWI), Modified NDWI (MNDWI), Improved Band Ratio (IBR) Method, and Automatic Water Extraction Index (AWEI) has been done along four different coastal stretches of India using multitemporal Landsat data...
June 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28499746/comparing-access-to-laser-capsulotomy-performed-by-optometrists-and-ophthalmologists-in-oklahoma-by-calculated-driving-distance-and-time
#13
Michael A Mahr, Jay C Erie
PURPOSE: To quantify Medicare beneficiary proximity to his or her yttrium-aluminum-garnet (YAG) laser capsulotomy-providing ophthalmologist and optometrist in Oklahoma by calculating driving distances and times. DESIGN: Cross-sectional cohort study using 2014 Oklahoma Medicare 100% and 5% data sets and Google Maps distance and travel time application programming interfaces. PARTICIPANTS: U.S. fee-for-service Medicare beneficiaries and Oklahoma ophthalmologist and optometrist laser capsulotomy providers...
May 9, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28478747/creation-of-a-virtual-antidotes-network-between-pharmacy-departments-of-catalan-hospitals
#14
Raquel Aguilar-Salmerón, Edurne Fernández de Gamarra-Martínez, Milagros García-Peláez, Antoni Broto-Sumalla, Lidia Martínez-Sánchez, Santiago Nogué-Xarau
Objetive: To design a virtual antidote network between hospitals that could help to locate on-line those hospitals that stocked those antidotes with the highest difficulty in terms of availability, and ensured that the medication was loaned in case of necessity. METHODS: The application was developed by four hospital pharmacists and two clinical toxicologists with the support of a Healthcare Informatics Consultant Company. RESULTS: The antidotes network in Catalonia, Spain, was launched in July 2015...
May 1, 2017: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/28471843/international-institutional-trauma-in-developmental-pediatric-practice
#15
Demetra Pappas, Jason Fogler, Sabrina Sargado, Leah Welchons, Marilyn Augustyn
"Aabis" is a school-aged boy from a predominantly conservative Muslim nation who presented to a tertiary developmental-behavioral pediatric (DBP) clinic to seek "expert opinion" for significant social and learning difficulties in the context of a history of frequent falling and "clumsiness." He was seen by a psychiatrist in his home country, who ordered an electroencephalogram and "brain map" (both normal), and received occupational and physical therapies. Frequent tantrums and intense emotional reactions to minor events-revealed to be related to a history of repeated physical beatings from groups of his "friends"-prompted referral to the DBP clinic...
April 18, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28459763/international-institutional-trauma-in-developmental-pediatric-practice
#16
Demetra Pappas, Jason Fogler, Sabrina Sargado, Leah Welchons, Marilyn Augustyn
"Aabis" is a school-aged boy from a predominantly conservative Muslim nation who presented to a tertiary developmental-behavioral pediatric (DBP) clinic to seek "expert opinion" for significant social and learning difficulties in the context of a history of frequent falling and "clumsiness." He was seen by a psychiatrist in his home country, who ordered an electroencephalogram and "brain map" (both normal), and received occupational and physical therapies. Frequent tantrums and intense emotional reactions to minor events-revealed to be related to a history of repeated physical beatings from groups of his "friends"-prompted referral to the DBP clinic...
May 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28459556/pred-skin-a-fast-and-reliable-web-application-to-assess-skin-sensitization-effect-of-chemicals
#17
Rodolpho C Braga, Vinicius M Alves, Eugene N Muratov, Judy Strickland, Nicole Kleinstreuer, Alexander Trospsha, Carolina Horta Andrade
Chemically induced skin sensitization is a complex immunological disease with a profound impact on quality of life and working ability. Despite some progress in developing alternative methods for assessing the skin sensitization potential of chemical substances, there is no in vitro test that correlates well with human data. Computational QSAR models provide a rapid screening approach and contribute valuable information for the assessment of chemical toxicity. We describe the development of a freely accessible web-based and mobile application for the identification of potential skin sensitizers...
May 22, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/28434408/secure-internet-of-things-based-cloud-framework-to-control-zika-virus-outbreak
#18
Sanjay Sareen, Sandeep K Sood, Sunil Kumar Gupta
OBJECTIVES: Zika virus (ZikaV) is currently one of the most important emerging viruses in the world which has caused outbreaks and epidemics and has also been associated with severe clinical manifestations and congenital malformations. Traditional approaches to combat the ZikaV outbreak are not effective for detection and control. The aim of this study is to propose a cloud-based system to prevent and control the spread of Zika virus disease using integration of mobile phones and Internet of Things (IoT)...
April 24, 2017: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/28382224/recutclub-com-an-open-source-whole-slide-image-based-pathology-education-system
#19
Paul A Christensen, Nathan E Lee, Michael J Thrall, Suzanne Z Powell, Patricia Chevez-Barrios, S Wesley Long
BACKGROUND: Our institution's pathology unknown conferences provide educational cases for our residents. However, the cases have not been previously available digitally, have not been collated for postconference review, and were not accessible to a wider audience. Our objective was to create an inexpensive whole slide image (WSI) education suite to address these limitations and improve the education of pathology trainees. MATERIALS AND METHODS: We surveyed residents regarding their preference between four unique WSI systems...
2017: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/28379077/perils-of-using-speed-zone-data-to-assess-real-world-compliance-to-speed-limits
#20
Anna Chevalier, Elizabeth Clarke, Aran John Chevalier, Julie Brown, Kristy Coxon, Rebecca Ivers, Lisa Keay
OBJECTIVE: Real-world driving studies, including those involving speeding alert devices and autonomous vehicles, can gauge an individual vehicle's speeding behavior by comparing measured speed with mapped speed zone data. However, there are complexities with developing and maintaining a database of mapped speed zones over a large geographic area that may lead to inaccuracies within the data set. When this approach is applied to large-scale real-world driving data or speeding alert device data to determine speeding behavior, these inaccuracies may result in invalid identification of speeding...
April 5, 2017: Traffic Injury Prevention
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