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R Nirupa, Satinder Gombar, Vanita Ahuja, Preeti Sharma
BACKGROUND AND AIMS: i-gel™ is a newer supraglottic airway device with a unique non-inflatable cuff. We aimed to compare i-gel™ with ProSeal™ laryngeal mask airway (PLMA™) in children scheduled for surgery under general anaesthesia (GA) with controlled ventilation. METHODS: This prospective, randomised controlled study was conducted in 100 surgical patients, aged 2-6 years of American Society of Anesthesiologists Physical Status I-II scheduled under GA. Patients were randomly allocated to receive either size 2 i-gel™ or PLMA™ as an airway device...
October 2016: Indian Journal of Anaesthesia
Joël L'Hermite, Elisabeth Dubout, Sophie Bouvet, Laure-Hélène Bracoud, Philippe Cuvillon, Jean-Emmanuel de La Coussaye, Jacques Ripart
BACKGROUND: Sore throat is a common complaint after surgery. It affects patient satisfaction and can affect activity after discharge. The supraglottic airway device (SAD) offers an alternative to traditional tracheal intubation with potential benefit in preventing sore throat. OBJECTIVE: The aim of this study was to compare the incidence of sore throat following three different SADs, the laryngeal mask airway Unique (LMA-U) and the more recent LMA Supreme (LMA-S) and the I-gel...
October 15, 2016: European Journal of Anaesthesiology
Young Yong Kim, Gu Hyun Kang, Won Hee Kim, Hyun Young Choi, Yong Soo Jang, Young Jae Lee, Jae Guk Kim, Hyeongtae Kim, Gyoung Yong Kim
OBJECTIVE: This study aimed to compare intubation performance between blind intubation through supraglottic airway devices and direct laryngoscopy by novices under manikin simulation. We hypothesized that the intubation time by novices using supraglottic airway devices was superior to that with the Macintosh laryngoscope (MCL). METHODS: A prospective, randomized crossover study was conducted with 95 participants, to evaluate i-gel, air-Q, LMA Fastrach, and MCL devices...
June 2016: Clin Exp Emerg Med
N Pratheeba, G S Ramya, R V Ranjan, R Remadevi
CONTEXT: Laryngeal mask airway (LMA) Classic™ has an inflatable cuff while i-gel™ has a noninflatable cuff made of thermoplastic elastomer. AIMS: To compare ease of insertion, number, and duration of insertion attempts among the two device. Secondary objectives were to evaluate the hemodynamic response and SpO2 during device insertion and during maintenance of general anesthesia. SETTINGS AND DESIGN: This study was conducted as randomized observational study in a teaching hospital...
September 2016: Anesthesia, Essays and Researches
Jodi Taylor, Sarah Black, Stephen J Brett, Kim Kirby, Jerry P Nolan, Barnaby C Reeves, Maria Robinson, Chris A Rogers, Lauren J Scott, Adrian South, Elizabeth A Stokes, Matthew Thomas, Sarah Voss, Sarah Wordsworth, Jonathan R Benger
Health outcomes after out of hospital cardiac arrest (OHCA) are extremely poor, with only 7-9% of patients in the United Kingdom (UK) surviving to hospital discharge. Currently emergency medical services (EMS) use either tracheal intubation or newer supraglottic airway devices (SGAs) to provide advanced airway management during OHCA. Equipoise between the two techniques has led to calls for a well-designed randomised controlled trial. The primary objective of the AIRWAYS-2 trial is to assess whether the clinical effectiveness of the i-gel, a second-generation SGA, is superior to tracheal intubation in the initial airway management of OHCA patients in the UK...
September 30, 2016: Resuscitation
Asako Watanabe, Mitsutaka Edanaga, Hiromichi Ichinose, Michiaki Yamakage
STUDY OBJECTIVES: Recently, i-Gel intubating laryngeal airway (ILA) has been frequently used because of the ease for airway insertion by residents and young anesthesiologists. However, it sometimes fails to fit or ventilate sufficiently in Japanese patients. Use of Air-Qsp, which is a new non-inflatable cuffed ILA, in a clinical setting has become possible. The purpose of this study was to compare the clinical performance of Air-Qsp with that of i-Gel for airway management in Japanese adult patients...
November 2016: Journal of Clinical Anesthesia
Cécile Magne, Vincent Pichenot, Péan Didier, Luc Bérard, Corinne Lejus-Bourdeau
BACKGROUND: Our purpose was to evaluate I-gel™ sizes 1 and 1.5. METHODS: I-Gel™ insertion was attempted in 60 children<2 years of age undergoing short elective surgery. The main endpoints were the determination of independent factors associated with successful first-attempt insertion and those associated with uneventful anaesthesia (i.e. no adverse events during insertion or during the intraoperative period of removal). RESULTS: Size 1 and a size 1...
September 23, 2016: Anaesthesia, Critical Care & Pain Medicine
Nicolas J Pejovic, Daniele Trevisanuto, Jolly J Nankunda, Thorkild Tylleskär
AIM: We compared the performance of personnel in a low-resource setting when they used the I-gel cuffless neonatal laryngeal mask or a face mask on a neonatal airway management manikin. METHODS: At Mulago Hospital, Uganda, 25 doctors, nurses and midwives involved in neonatal resuscitation were given brief training with the I-gel and face mask. Then, every participant was observed positioning both devices on three consecutive occasions. The success rate and insertion times leading to effective positive pressure ventilation (PPV) were recorded...
September 1, 2016: Acta Paediatrica
Souvik Maitra, Dalim K Baidya, Mahesh K Arora, Sulagna Bhattacharjee, Puneet Khanna
STUDY OBJECTIVE: i-gel is a single-use supraglottic airway device that has a gastric drain tube similar to laryngeal mask airway (LMA) ProSeal. Randomized trials, when compared i-gel with LMA ProSeal, reported a differing results. Primary objective of this study is to compare LMA ProSeal and i-gel in terms of oropharyngeal leak pressure. DESIGN: Meta-analysis of randomized controlled trials where i-gel has been compared to LMA ProSeal in adult airway management during general anesthesia...
September 2016: Journal of Clinical Anesthesia
Kazuo Hattori, Nobuyasu Komasawa, Yu Miyazaki, Haruki Kido, Shiho Deguchi, Toshiaki Minami
STUDY OBJECTIVE: This study aimed to determine whether muscle relaxants facilitates insertion efficacy of the i-gel supraglottic device (i-gel) by novice doctors in anesthetized patients. DESIGN: Randomized clinical trial. SETTING: Operating room. PATIENTS: Seventy adult patients scheduled for elective surgery under general anesthesia. INTERVENTIONS: Seventy adult patients were assigned to the rocuronium (MR group; 35 patients) or control group (C group; 35 patients)...
September 2016: Journal of Clinical Anesthesia
Geoffrey Haw Chieh Liew, Esther Dawen Yu, Shitalkumar Sharad Shah, Harikrishnan Kothandan
INTRODUCTION: The LMA Supreme™, i-gel® and LMA ProSeal™ are second-generation supraglottic airway devices. We tested the hypothesis that these devices differ in performance when used for spontaneous ventilation during anaesthesia. METHODS: 150 patients who underwent general anaesthesia for elective surgery were randomly allocated into three groups. Data was collected on oropharyngeal leak pressures, ease and duration of device insertion, ease of gastric tube insertion, and airway safety...
August 2016: Singapore Medical Journal
Zhiqing Gu, Quanying Jin, Junjun Liu, Lianhua Chen
The shortcomings of laryngeal mask airway (LMA™), such as upper airway obstruction and gastric distension or airway leakage, may limit its application in small children. The I-gel™ (I-gel), LMA-Supreme™ (LMA-S), and Ambu AuraOnce™ (Ambu) are three improvements upon these shortcomings. This study adopted respiratory dynamic monitoring to observe the ventilation parameters of the three laryngeal masks in small children. A total of 105 children were randomized into Ambu (n = 35), I-gel (n = 35), and LMA-S (n = 35) groups...
August 4, 2016: Journal of Clinical Monitoring and Computing
Latha Naik, Neerja Bhardwaj, Indu Mohini Sen, Rakesh V Sondekoppam
Introduction. The study aims to test whether flexible silicone tubes (FST) improve performance and provide similar intubation success through I-Gel as compared to ILMA. Our trial is registered in CTRI and the registration number is "CTRI/2016/06/006997." Methods. One hundred and twenty ASA status I-II patients scheduled for elective surgical procedures needing tracheal intubation were randomised to endotracheal intubation using FST through either I-Gel or ILMA. In the ILMA group (n = 60), intubation was attempted through ILMA using FST and, in the I-Gel group (n = 60), FST was inserted through I-Gel airway...
2016: Anesthesiology Research and Practice
Christine A Fiddler, Helen Parfrey, Andrew S Cowburn, Ding Luo, Gerard B Nash, Gillian Murphy, Edwin R Chilvers
Aminopeptidase N (CD13) is a widely expressed cell surface metallopeptidase involved in the migration of cancer and endothelial cells. Apart from our demonstration that CD13 modulates the efficacy of tumor necrosis factor-α-induced apoptosis in neutrophils, no other function for CD13 has been ascribed in this cell. We hypothesized that CD13 may be involved in neutrophil migration and/or homotypic aggregation. Using purified human blood neutrophils we confirmed the expression of CD13 on neutrophils and its up-regulation by pro-inflammatory agonists...
2016: PloS One
Mackenzie Katheryn Herroon, Jonathan Driscoll Diedrich, Izabela Podgorski
Adipocytes are a major component of the bone marrow that can critically affect metastatic progression in bone. Understanding how the marrow fat cells influence growth, behavior, and survival of tumor cells requires utilization of in vitro cell systems that can closely mimic the physiological microenvironment. Herein, we present two new three-dimensional (3D) culture approaches to study adipocyte-tumor cell interactions in vitro. The first is a transwell-based system composed of the marrow-derived adipocytes in 3D collagen I gels and reconstituted basement membrane-overlayed prostate tumor cell spheroids...
2016: Frontiers in Endocrinology
Gökhan Peker, Suna Akın Takmaz, Bülent Baltacı, Hülya Başar, Mustafa Kotanoğlu
OBJECTIVE: The aim of this study was to compare insertion parameters of four different types of supraglottic airway devices (SGAD) (Classic LMA, I-gel LMA, Proseal LMA, Cobra PLA) in children undergoing ophthalmic surgery and to determine the effect on intra-ocular pressure (IOP) and haemodynamic responses during insertion. METHODS: Sixty American society of Anesthesiologists (ASA) I-II children aged 1-10 years undergoing extra-ocular ophthalmic surgery were randomly divided into four groups (Group LMA, Group I-gel LMA, Group PLMA and Group CPLA) in this prospective, randomised study...
October 2015: Turkish Journal of Anaesthesiology and Reanimation
Dilek Erdoğan Arı, Arzu Yıldırım Ar, Ceren Şanlı Karip, İncifer Siyahkoç, Ahmet Hakan Arslan, Fatma Nur Akgün
OBJECTIVE: I-gel is a new supraglottic airway device without an inflatable cuff. We aimed to compare I-gel and the classic laryngeal mask airway (LMA) regarding the ease of use and clinical performance in Turkish population. METHODS: Fifty American Society of Anesthesiologists (ASA) I-II patients were randomly allocated into two groups: Group I-gel and Group LMA. Insertion time and success in first attempt were recorded. Peak, plato and mean airway pressures, EtCO2, airway compliance and leak volume were periodically recorded during the operation...
October 2015: Turkish Journal of Anaesthesiology and Reanimation
Mansoor Aqil, Bilal Delvi, Abdullah Abujamea, Tariq Alzahrani, Abdulrahman Alzahem, Saara Mansoor, Ayman Aaljazaeri
BACKGROUND: Gross morphological differences exist among different brands of pediatric supraglottic devices (SGDs). The aim of this study is to compare the spatial relationship of i-gel® and Ambu® AuraOnce (AO)TM on pediatric airway based on three dimensional (3-D) magnetic resonance imaging (MRI) measurements. METHODS: Sixty patients up to 12 years of age were enrolled and assigned in two groups, i-gel® or Ambu® AOTM. After confirmation of proper placement of these SGDs, 3-D MRI scans of head and neck were performed...
June 17, 2016: Minerva Anestesiologica
W Kim, H Y Choi, Y S Jang, G H Kang
No abstract text is available yet for this article.
December 2015: Intensive Care Medicine Experimental
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