keyword
MENU ▼
Read by QxMD icon Read
search

i-gel

keyword
https://www.readbyqxmd.com/read/28518082/maturation-of-human-stem-cell-derived-cardiomyocytes-in-biowires-using-electrical-stimulation
#1
Xuetao Sun, Sara S Nunes
Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have been a promising cell source and have thus encouraged the investigation of their potential applications in cardiac research, including drug discovery, disease modeling, tissue engineering, and regenerative medicine. However, cells produced by existing protocols display a range of immaturity compared with native adult ventricular cardiomyocytes. Many efforts have been made to mature hPSC-CMs, with only moderate maturation attained thus far. Therefore, an engineered system, called biowire, has been devised by providing both physical and electrical cues to lead hPSC-CMs to a more mature state in vitro...
May 6, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28489804/comparison-of-learning-performance-of-2-intubating-laryngeal-mask-airways-in-novice-a-randomized-crossover-manikin-study
#2
Zi-Jia Liu, Jie Yi, Wei-Yun Chen, Xiu-Hua Zhang, Yu-Guang Huang
BACKGROUND: Intubating laryngeal mask airways (LMAs) such as i-gel and Aura-i could serve as rescue devices in resuscitation and further ensure the airway by facilitating trachea intubation without ventilation interruption. But data regarding intubating LMAs in novice are limited and skill degeneration without regular training has not been evaluated. So we designed this prospective randomized crossover manikin study to compare the learning performance of 2 intubating LMAs (i-gel and Aura-i)...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28471973/a-randomized-comparison-of-volume-and-pressure-controlled-ventilation-in-children-with-the-i-gel-effects-on-peak-inspiratory-pressure-oropharyngeal-leak-pressure-and-gastric-insufflation
#3
Jin Ha Park, Ji Young Kim, Kyoungun Park, Hae Keum Kil
BACKGROUND: The i-gel provides good airway sealing but gastric insufflation may occur when peak inspiratory pressure (PIP) exceeds the sealing pressure of the i-gel without a gastric tube. Pressure-controlled ventilation (PCV) provides lower PIP compared with volume-controlled ventilation (VCV) and low PIP may reduce the incidence of gastric insufflation in children during positive pressure ventilation. This study was designed to evaluate PIP, oropharyngeal leak pressure, and gastric insufflation during VCV or PCV in children undergoing general anesthesia with i-gel without a gastric tube in situ...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28439597/ambu-auraonce-versus-i-gel-laryngeal-mask-airway-in-infants-and-children-undergoing-surgical-procedures-a-randomized-controlled-trial
#4
Abdulrahman M Alzahem, Mansoor Aqil, Tariq A Alzahrani, Ayman H Aljazaeri
To compare the efficacy and performance of the pediatric Ambu AuraOnce (Ambu AO) mask (Ambu, Copenhagen, Denmark) and i-gel mask (Intersurgical Ltd., Wokingham, United Kingdom). Methods: From May 2015 to September 2016, 112 patients, 0-14 years old, underwent elective surgery at a tertiary university hospital (Riyadh, Saudi Arabia). They were randomly assigned to the Ambu AO or i-gel group. Three groups underwent a subgroup analysis: ≤5 kg (group 1), 5.1-10.0 kg (group 2), and >10 kg (group 3). Results: The oropharyngeal leak pressure was significantly higher for the i-gel (25...
May 2017: Saudi Medical Journal
https://www.readbyqxmd.com/read/28423706/identification-of-ras-suppressor-1-rsu-1-as-a-potential-breast-cancer-metastasis-biomarker-using-a-three-dimensional-in-vitro-approach
#5
Vasiliki Gkretsi, Andreas Stylianou, Maria Louca, Triantafyllos Stylianopoulos
Breast cancer (BC) is the most common malignant disease in women, with most patients dying from metastasis to distant organs, making discovery of novel metastasis biomarkers and therapeutic targets imperative. Extracellular matrix (ECM)-related adhesion proteins as well as tumor matrix stiffness are important determinants for metastasis. As traditional two-dimensional culture does not take into account ECM stiffness, we employed 3-dimensional collagen I gels of increasing concentration and stiffness to embed BC cells of different invasiveness (MCF-7, MDA-MB-231 and MDA-MB-231-LM2) or tumor spheroids...
April 18, 2017: Oncotarget
https://www.readbyqxmd.com/read/28245809/mesenchymal-stem-cells-and-myoblast-differentiation-under-hgf-and-igf-1-stimulation-for-3d-skeletal-muscle-tissue-engineering
#6
R Witt, A Weigand, A M Boos, A Cai, D Dippold, A R Boccaccini, D W Schubert, M Hardt, C Lange, A Arkudas, R E Horch, J P Beier
BACKGROUND: Volumetric muscle loss caused by trauma or after tumour surgery exceeds the natural regeneration capacity of skeletal muscle. Hence, the future goal of tissue engineering (TE) is the replacement and repair of lost muscle tissue by newly generating skeletal muscle combining different cell sources, such as myoblasts and mesenchymal stem cells (MSCs), within a three-dimensional matrix. Latest research showed that seeding skeletal muscle cells on aligned constructs enhance the formation of myotubes as well as cell alignment and may provide a further step towards the clinical application of engineered skeletal muscle...
February 28, 2017: BMC Cell Biology
https://www.readbyqxmd.com/read/28236864/a-comparison-of-various-supraglottic-airway-devices-for-fiberoptical-guided-tracheal-intubation
#7
Thomas Metterlein, Anna Dintenfelder, Christoph Plank, Bernhard Graf, Gabriel Roth
BACKGROUND: Fiberoptical assisted intubation via placed supraglottic airway devices has been described as safe and easy procedure to manage difficult airways. However visualization of the glottis aperture is essential for fiberoptical assisted intubation. Various different supraglottic airway devices are commercially available and might offer different conditions for fiberoptical assisted intubation. The aim of this study was to compare the best obtainable view of the glottic aperture using different supraglottic airway devices...
March 2017: Brazilian Journal of Anesthesiology
https://www.readbyqxmd.com/read/28209486/vasodilator-stimulated-phosphoprotein-vasp-depletion-from-breast-cancer-mda-mb-231-cells-inhibits-tumor-spheroid-invasion-through-downregulation-of-migfilin-%C3%AE-catenin-and-urokinase-plasminogen-activator-upa
#8
Vasiliki Gkretsi, Andreas Stylianou, Triantafyllos Stylianopoulos
A hallmark of cancer cells is their ability to invade surrounding tissues and form metastases. Cell-extracellular matrix (ECM)-adhesion proteins are crucial in metastasis, connecting tumor ECM with actin cytoskeleton thus enabling cells to respond to mechanical cues. Vasodilator-stimulated phosphoprotein (VASP) is an actin-polymerization regulator which interacts with cell-ECM adhesion protein Migfilin, and regulates cell migration. We compared VASP expression in MCF-7 and MDA-MB-231 breast cancer (BC) cells and found that more invasive MDA-MB-231 cells overexpress VASP...
March 15, 2017: Experimental Cell Research
https://www.readbyqxmd.com/read/28194529/a-randomized-clinical-study-on-postoperative-pain-comparing-between-the-supraglottic-airway-device-and-endotracheal-tubing-in-transabdominal-preperitoneal-repair-tapp
#9
Y Nagahisa, K Hashida, R Matsumoto, R Kawashima, M Okabe, K Kawamoto
BACKGROUND: Transabdominal preperitoneal (TAPP) repair is the most widely used laparoscopic technique for the treatment of inguinal hernia in Japan. Many studies have shown that in comparison with open hernia repair, laparoscopic repair results in less pain and a shorter convalescence. However, postoperative pain remains a concern. One possible cause of postoperative pain in the early postoperative phase is strain or cough on removal of the endotracheal tube. Use of a supraglottic airway (SGA) device helps to avoid such complaints...
February 13, 2017: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/28164708/expanding-proteome-coverage-with-charge-ordered-parallel-ion-analysis-chopin-combined-with-broad-specificity-proteolysis
#10
Simon Davis, Philip D Charles, Lin He, Peter Mowlds, Benedikt M Kessler, Roman Fischer
The "deep" proteome has been accessible by mass spectrometry for some time. However, the number of proteins identified in cells of the same type has plateaued at ∼8000-10 000 without ID transfer from reference proteomes/data. Moreover, limited sequence coverage hampers the discrimination of protein isoforms when using trypsin as standard protease. Multienzyme approaches appear to improve sequence coverage and subsequent isoform discrimination. Here we expanded proteome and protein sequence coverage in MCF-7 breast cancer cells to an as yet unmatched depth by employing a workflow that addresses current limitations in deep proteome analysis in multiple stages: We used (i) gel-aided sample preparation (GASP) and combined trypsin/elastase digests to increase peptide orthogonality, (ii) concatenated high-pH prefractionation, and (iii) CHarge Ordered Parallel Ion aNalysis (CHOPIN), available on an Orbitrap Fusion (Lumos) mass spectrometer, to achieve 57% median protein sequence coverage in 13 728 protein groups (8949 Unigene IDs) in a single cell line...
March 3, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/28153678/i-gel-o2-resus-pack-a-rescue-device-in-case-of-severe-facial-injury-and-difficult-intubation
#11
Fabio Baratto, Giulia Gabellini, Anrdea Paoli, Annalisa Boscolo
No abstract text is available yet for this article.
January 26, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28125979/i-gel-is-a-suitable-alternative-to-endotracheal-tubes-in-the-laparoscopic-pneumoperitoneum-and-trendelenburg-position
#12
Chih-Jun Lai, Chih-Min Liu, Chun-Yu Wu, Feng-Fang Tsai, Ping-Huei Tseng, Shou-Zen Fan
BACKGROUND: The use of supraglottic airway devices (SADs) in surgeries with laparoscopic pneumoperitoneum and Trendelenburg (LPT) positioning is controversial due to concerns about insufficient pulmonary ventilation and aspiration. In this prospective, randomized-controlled trial, we evaluated whether the i-gel, a new second generation SAD, provides an effective alternative to an endotracheal tube (ETT) by comparing respiratory parameters and perioperative respiratory complications in non-obese patients...
January 6, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28095754/three-dimensional-coculture-of-meniscal-cells-and-mesenchymal-stem-cells-in-collagen-type-i-hydrogel-on-a-small-intestinal-matrix-a-pilot-study-toward-equine-meniscus-tissue-engineering
#13
Antje Kremer, Iris Ribitsch, Jenny Reboredo, Julia Dürr, Monika Egerbacher, Florien Jenner, Heike Walles
Meniscal injuries are the most frequently encountered soft tissue injuries in the equine stifle joint. Due to the inherent limited repair potential of meniscal tissue, meniscal injuries do not only affect the meniscus itself but also lead to impaired joint homeostasis and secondary osteoarthritis. The presented study compares 3D coculture constructs of primary equine mesenchymal stem cells (MSC) and meniscus cells (MC) seeded on three different scaffolds-a cell-laden collagen type I hydrogel (Col I gel), a tissue-derived small intestinal matrix scaffold (SIS-muc) and a combination thereof-for their qualification to be applied for meniscus tissue engineering...
May 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28089425/-a-comparison-of-various-supraglottic-airway-devices-for-fiberoptical-guided-tracheal-intubation
#14
Thomas Metterlein, Anna Dintenfelder, Christoph Plank, Bernhard Graf, Gabriel Roth
BACKGROUND: Fiberoptical assisted intubation via placed supraglottic airway devices has been described as safe and easy procedure to manage difficult airways. However visualization of the glottis aperture is essential for fiberoptical assisted intubation. Various different supraglottic airway devices are commercially available and might offer different conditions for fiberoptical assisted intubation. The aim of this study was to compare the best obtainable view of the glottic aperture using different supraglottic airway devices...
March 2017: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/28072732/comparison-of-the-i-gel-and-other-supraglottic-airways-in-adult-manikin-studies-systematic-review-and-meta-analysis
#15
Jiwon An, Sang Beom Nam, Jong Seok Lee, Jinae Lee, Hanna Yoo, Hye Mi Lee, Min-Soo Kim
BACKGROUND: The i-gel has a gel-like cuff composed of thermoplastic elastomer that does not require cuff inflation. As the elimination of cuff inflation may shorten insertion time, the i-gel might be a useful tool in emergency situations requiring prompt airway care. This systematic review and meta-analysis of previous adult manikin studies for inexperienced personnel was performed to compare the i-gel with other supraglottic airways. METHODS: We searched PubMed, the Cochrane Library, and EMBASE for eligible randomized controlled trials (RCTs) published before June 2015, including with a crossover design, using the following search terms: "i-gel," "igel," "simulation," "manikin," "manikins," "mannequin," and "mannequins...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27993429/a-comparison-of-the-macintosh-laryngoscope-and-blind-intubation-via-i-gel-in-intubating-an-entrapped-patient-a-randomized-crossover-manikin-study
#16
Karol Bielski, Jacek Smereka, Jerzy R Ladny, Lukasz Szarpak
No abstract text is available yet for this article.
November 22, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27977899/individual-evaluation-of-cardiac-marker-expression-and-self-beating-during-cardiac-differentiation-of-p19cl6-cells-on-different-culture-substrates
#17
Tetsuji Yamaoka, Mitsuhi Hirata, Takaaki Dan, Atsushi Yamashita, Akihisa Otaka, Takahiko Nakaoki, Azizi Miskon, Sachiro Kakinoki, Atsushi Mahara
Cell-based therapies using self-beating cardiomyocytes have been attracting great attention for use in cardiac regeneration, although an effective procedure to improve cardiac differentiation and self-beating induction is required. The purpose of this study is to clarify the effect of the culture substrate on cardiac maturation by separately evaluating the cardiac differentiation step and the beating induction step in vitro. To this end, the well-studied cardiomyocyte-like progenitor cell line P19CL6 and neonatal cardiomyocytes (NCMs) were selected and cultured on substrates coated with collagen type I (Col-I), gelatin (Gel), fibronectin (FN), or poly-l-lysine (PLL)...
April 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/27930894/the-i-gel-supraglottic-airway-as-a-conduit-for-fibreoptic-tracheal-intubation-a-randomized-comparison-with-the-single-use-intubating-laryngeal-mask-airway-and-ctrach-laryngeal-mask-in-patients-with-predicted-difficult-laryngoscopy
#18
Pavel Michálek, Will Donaldson, Francis McAleavey, Alexander Abraham, Rachel J Mathers, Claire Telford
Fibreoptic intubation through a supraglottic airway is an alternative plan for airway management in difficult or failed laryngoscopy. The aim of this study was to compare three supraglottic airways as conduits in patients with at least one predictor for difficult laryngoscopy. The i-gel was compared with the single-use intubating laryngeal mask airway (sILMA) and CTrach laryngeal mask in 120 adult patients scheduled for elective surgeries under general anaesthesia using a prospective, randomized and single-blinded design...
2016: Prague Medical Report
https://www.readbyqxmd.com/read/27924197/dexmedetomidine-infusion-as-an-anesthetic-adjuvant-to-general-anesthesia-for-appropriate-surgical-field-visibility-during-modified-radical-mastectomy-with-i-gel%C3%A2-a-randomized-control-study
#19
Kumkum Gupta, Bhawana Rastogi, Prashant K Gupta, Ivesh Singh, Vijendra Pal Singh, Manish Jain
BACKGROUND: Modified radical mastectomy is associated with appreciable blood loss, while endotracheal intubation leads to elevated hemodynamic responses. The present study aimed to evaluate the clinical efficacy of dexmedetomidine infusion as an anesthetic adjuvant to general anesthesia during modified radical mastectomy with I-Gel. METHODS: Sixty adult consenting female patients, of American Society of Anesthesiologists physical status 1 to 2 and aged 4,065 years, were blindly randomized into two groups of 30 patients each...
December 2016: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/27899211/are-nurses-able-to-perform-blind-intubation-randomized-comparison-of-i-gel-and-laryngeal-mask-airway
#20
Jerzy R Ladny, Karol Bielski, Lukasz Szarpak, Michal Cieciel, Roman Konski, Jacek Smereka
No abstract text is available yet for this article.
November 22, 2016: American Journal of Emergency Medicine
keyword
keyword
34178
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"