keyword
https://read.qxmd.com/read/38696874/cadmium-promoted-lps-induced-inflammation-through-tlr4-i%C3%AE%C2%BAb%C3%AE-nf%C3%AE%C2%BA-b-signaling-by-increasing-ros-mediated-incomplete-autophagy
#1
JOURNAL ARTICLE
Chuanzhi Guo, Jiacheng Ruan, Zehua Li, Huilin Fu, Kongdong Li, Xun Gong, Xin Gu, Jie Gu, Haifeng Shi
Cadmium (Cd) exposure is considered as non-infectious stressor to human and animal health. Recent studies suggest that the immunotoxicity of low dose Cd is not directly apparent, but disrupts the immune responses when infected with some bacteria or virus. But how Cd alters the adaptive immunity organ and cells remains unclear. In this study, we applied lipopolysaccharide (LPS, infectious stressor) to induced inflammation in spleen tissues and T cells, and investigated the effects after Cd exposure and the underlying mechanism...
May 1, 2024: Ecotoxicology and Environmental Safety
https://read.qxmd.com/read/38692149/passive-biomonitoring-of-airborne-microplastics-using-lichens-a-comparison-between-urban-natural-and-protected-environments
#2
JOURNAL ARTICLE
Davide Taurozzi, Luca Gallitelli, Giulia Cesarini, Susanna Romano, Monica Orsini, Massimiliano Scalici
Currently, natural and urban ecosystems are affected by different types of atmospheric deposition, which can compromise the balance of the environment. Plastic pollution represents one of the major threats for biota, including lichens. Epiphytic lichens have value as bioindicators of environmental pollution, climate change, and anthropic impacts. In this study, we aim to investigate the lichen bioaccumulation of airborne microplastics along an anthropogenic pollution gradient. We sampled lichens from the Genera Cladonia and Xanthoria to highlight the effectiveness of lichens as tools for passive biomonitoring of microplastics...
April 26, 2024: Environment International
https://read.qxmd.com/read/38690838/improvement-of-photovoltaic-performance-of-perovskite-solar-cells-by-synergistic-modulation-of-sno-2-and-perovskite-via-interfacial-modification
#3
JOURNAL ARTICLE
Jinliang Shen, Xiang Ge, Qing Ge, Na Li, Yuhang Wang, Xudong Liu, Junlei Tao, Tingwei He, Shaopeng Yang
In the past decade, perovskite solar cell (PSC) photoelectric conversion efficiency has advanced significantly, and tin dioxide (SnO2 ) has been extensively used as the electron transport layer (ETL). Due to its high electron mobility, strong chemical stability, energy level matching with perovskite, and easy low-temperature fabrication, SnO2 is one of the most effective ETL materials. However, the SnO2 material as an ETL has its limitations. For example, SnO2 films prepared by low-temperature spin-coating contain a large number of oxygen vacancies, resulting in energy loss and high open-circuit voltage ( V OC ) loss...
May 1, 2024: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/38686891/highly-stable-localized-surface-plasmon-resonance-of-cu-nanoparticles-obtained-via-oxygen-plasma-irradiation
#4
JOURNAL ARTICLE
Yingcui Fang, Bin Xu, Shuai Wang, Hongjun Liu, Jie Wang, Mengting Si
Copper nanoparticles (CuNPs) possess strong localized surface plasmon resonance (LSPR) in visible light. However, CuNPs are not chemically stable in air, which has seriously hindered the applications based on the LSPR of CuNPs. We developed an artificial method to passivate CuNPs as Al naturally does in air, preventing the oxidation of CuNPs through swift oxidation of the surface atoms via oxygen plasma irradiation. A hemispheric core-shell structure of CuNPs uniformly covered by a dense CuO shell (CuNPs@d-CuO) was constructed...
April 30, 2024: Nanoscale
https://read.qxmd.com/read/38673181/corrosion-induced-on-aluminum-by-biodiesel-components-in-non-oxygen-environments
#5
JOURNAL ARTICLE
Fabiola Vergara-Juarez, Jesus Porcayo-Calderon, Juan Pablo Perez-Orozco, Macdiel Emilio Acevedo-Quiroz, Victoria Bustos-Terrones, Alfredo Quinto-Hernandez
Biodiesel is a mixture of saturated and unsaturated Fatty Acid Methyl Esters (FAMEs) whose composition affects the corrosion behavior of metal containers during storage. This study examines the effect of the C=C bond present in selected FAMEs (Methyl Stearate, Methyl Oleate, and Methyl Linoleate) in aluminum corrosion in the absence of oxygen. First, mass loss assays were carried out at 100, 200, and 280 °C for 1000 h using pure Methyl Stearate (MS), 5% Methyl Oleate in Methyl Stearate (MS-5% MO), and 5% Methyl Linoleate in Methyl Stearate (MS-5% ML)...
April 16, 2024: Materials
https://read.qxmd.com/read/38669997/highly-efficient-deep-blue-emitting-cspbbr-3-nanoplatelets-synthesized-via-surface-ligand-mediated-strategy
#6
JOURNAL ARTICLE
Xue Zhang, Yanyu Cui, Siyuan Ye, Zhuohan Lin, Yan Li
Two-dimensional (2D) CsPbBr3 nanoplatelets (NPLs) have attracted great attention as one of promising semiconductor nanomaterials due to their large exciton binding energy and narrow emission spectra. However, the labile ionic and weakly bound surfaces of deep-blue emitting CsPbBr3 NPLs with wide bandgap result in their colloidal instability, thus degrading their optical properties. It is challenging to obtain deep-blue emitting CsPbBr3 NPLs with excellent optical properties. In this study, high-quality blue-emitting CsPbBr3 NPLs with tunable thickness were prepared adopting the DBSA-mediated confinement effect based on the hot-injection method...
March 30, 2024: Journal of Colloid and Interface Science
https://read.qxmd.com/read/38668498/oxidative-dissolution-process-of-sphalerite-in-fe-2-so-4-3-o-3-system-implications-for-heavy-metals-removal-and-recovery
#7
JOURNAL ARTICLE
Mingtong Zhang, Hongbo Zhao, Yisheng Zhang, Xin Lv, Luyuan Zhang, Li Shen, Liang Hu, Jiankang Wen, Louyan Shen, Xianping Luo
Metal sulfides in waste rocks and tailings are susceptible to serious soil and water contamination due to the generation of acid mine drainage (AMD) during stockpiling. The hydrometallurgical process is one of the most essential heavy metal remediation technologies through harmless disposal and resource utilization of the waste sulfides. However, atmospheric hydrometallurgy of sulfides still faces great challenges due to low leaching efficiency and high cost. In this work, we proposed a cooperative leaching system (Fe2 (SO4 )3 -O3 ) and investigated the oxidative dissolution process of sphalerite (ZnS)...
April 8, 2024: Toxics
https://read.qxmd.com/read/38668147/hexylammonium-acetate-regulated-buried-interface-for-efficient-and-stable-perovskite-solar-cells
#8
JOURNAL ARTICLE
Ruiyuan Hu, Taomiao Wang, Fei Wang, Yongjun Li, Yonggui Sun, Xiao Liang, Xianfang Zhou, Guo Yang, Qiannan Li, Fan Zhang, Quanyao Zhu, Xing'ao Li, Hanlin Hu
Due to current issues of energy-level mismatch and low transport efficiency in commonly used electron transport layers (ETLs), such as TiO2 and SnO2 , finding a more effective method to passivate the ETL and perovskite interface has become an urgent matter. In this work, we integrated a new material, the ionic liquid (IL) hexylammonium acetate (HAAc), into the SnO2 /perovskite interface to improve performance via the improvement of perovskite quality formed by the two-step method. The IL anions fill oxygen vacancy defects in SnO2 , while the IL cations interact chemically with Pb2+ within the perovskite structure, reducing defects and optimizing the morphology of the perovskite film such that the energy levels of the ETL and perovskite become better matched...
April 9, 2024: Nanomaterials
https://read.qxmd.com/read/38666450/endogenous-melanin-and-hydrogen-based-specific-activated-theranostics-nanoagents-a-novel-multi-treatment-paradigm-for-rheumatoid-arthritis
#9
JOURNAL ARTICLE
Lin Chen, Mingxin Zhao, Weiwei Kang, Lujie Yu, Chongqing Zhang, Shutong Wu, Xiaorui Song, Keqi Zhao, Pengmin Liu, Qin Liu, Rong Dai, Ziliang Zheng, Ruiping Zhang
Rheumatoid arthritis (RA) is a systemic autoimmune disorder characterized by excessive proliferation of rheumatoid arthritis synovial fibroblasts (RASFs) and accumulation of inflammatory cytokines. Exploring the suppression of RASFs and modulation of the RA microenvironment is considered a comprehensive strategy for RA. In this work, specifically activated nanoagents (MAHI NGs) based on the hypoxic and weakly acidic RA microenvironment are developed to achieve a second near-infrared fluorescence (NIR-II FL)/photoacoustic (PA) dual-model imaging-guided multi-treatment...
April 26, 2024: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://read.qxmd.com/read/38657902/nanozyme-based-visual-diagnosis-and-therapeutics-for-myocardial-infarction-the-application-and-strategy
#10
REVIEW
Yuan Zhang, Wanpeng Yu, Lei Zhang, Peifeng Li
BACKGROUND: Myocardial infarction (MI) is a heart injury caused by ischemia and low oxygen conditions. The occurrence of MI lead to the activation of a large number of neutrophils and macrophages, inducing severe inflammatory injury. Meanwhile, the inflammatory response produces much more free radicals, further exacerbating the inflammatory response and tissue damage. Efforts are being dedicated to developing antioxidants and enzymes, as well as small molecule drugs, for treating myocardial ischemia...
April 22, 2024: Journal of Advanced Research
https://read.qxmd.com/read/38651809/light-induced-photoluminescence-enhancement-in-chiral-cdse-quantum-dot-films
#11
JOURNAL ARTICLE
Yang Wang, Pan Liang, Yumeng Men, Meizhen Jiang, Lin Cheng, Jinlei Li, Tianqing Jia, Zhenrong Sun, Donghai Feng
Chiral quantum dots (QDs) are promising materials applied in many areas, such as chiral molecular recognition and spin selective filter for charge transport, and can be prepared by facile ligand exchange approaches. However, ligand exchange leads to an increase in surface defects and reduces the efficiencies of radiative recombination and charge transport, which restricts further applications. Here, we investigate the light-induced photoluminescence (PL) enhancement in chiral L- and D-cysteine CdSe QD thin films, providing a strategy to increase the PL...
April 28, 2024: Journal of Chemical Physics
https://read.qxmd.com/read/38650173/regulating-the-electron-distribution-of-metal-oxygen-for-enhanced-oxygen-stability-in-li-rich-layered-cathodes
#12
JOURNAL ARTICLE
Zijia Yin, Jun Zhao, Dong Luo, Yi-Ying Chin, Chien-Te Chen, Huaican Chen, Wen Yin, Yu Tang, Tingting Yang, Jincan Ren, Tianyi Li, Kamila M Wiaderek, Qingyu Kong, Jun Fan, He Zhu, Yang Ren, Qi Liu
Li-rich Mn-based layered oxides (LLO) hold great promise as cathode materials for lithium-ion batteries (LIBs) due to their unique oxygen redox (OR) chemistry, which enables additional capacity. However, the LLOs face challenges related to the instability of their OR process due to the weak transition metal (TM)-oxygen bond, leading to oxygen loss and irreversible phase transition that results in severe capacity and voltage decay. Herein, a synergistic electronic regulation strategy of surface and interior structures to enhance oxygen stability is proposed...
April 22, 2024: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://read.qxmd.com/read/38628989/a-rare-case-of-a-patient-being-alert-and-communicative-despite-severe-hypothermia
#13
Emile Jeunesse, Patrick O'Malley, Nick Petrus, Chelsea McCoy
Hypothermia is defined as a significant drop in core body temperature below 35°C (95°F). It is traditionally staged as mild, moderate, severe, and profound at temperatures of 35°C to 32°C (95°F to 89.6°F), 32°C to 28°C (89.6°F to 82.4°F), <28°C (<82.4°F), and <24°C (75.2°F), respectively. It can also be classified into the same stages by clinical presentations. We present a patient that fits into two different stages based on core body temperature and clinical presentation...
March 2024: Curēus
https://read.qxmd.com/read/38624192/inspiratory-muscle-training-in-phase-1-and-2-postoperative-cardiac-rehabilitation-following-coronary-artery-bypass-graft-surgery-systematic-review-with-meta-analysis
#14
JOURNAL ARTICLE
Clênia Oliveira Araújo, Carla Cristina Araújo Alves, Francisco R A Santos, Lawrence P Cahalin, Graziella França Bernardelli Cipriano, Gerson Cipriano
OBJECTIVE: This study aimed to determine the effects of inspiratory muscle training (IMT) on exercise capacity, respiratory muscle strength, length of hospital stay (LOS), and quality of life (QOL) following coronary artery bypass graft surgery. METHODS: The search was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and the Cochrane Handbook and included the databases MEDLINE, EMBASE, CINAHL, Scopus, and CENTRAL...
April 16, 2024: Physical Therapy
https://read.qxmd.com/read/38623770/fractional-amplitude-of-low-frequency-fluctuation-and-voxel-mirrored-homotopic-connectivity-in-patients-with-persistent-postural-perceptual-dizziness-resting-state-functional-magnetic-resonance-imaging-study
#15
JOURNAL ARTICLE
Yueji Liu, Xiyu Peng, Cunxin Lin, Dan Liu, Yang Sun, Feiran Huang, Tengfei Liu, Lijie Xiao, Xiue Wei, Kai Wang, Zhengwei Chen, Liangqun Rong
PURPOSE: Persistent postural-perception dizziness (PPPD) is a chronic subjective form of dizziness characterized by the exacerbation of dizziness with active or passive movement, complex visual stimuli, and upright posture. Therefore, we aimed to analyze the resting-state functional magnetic resonance imaging (fMRI) in patients with PPPD using fractional amplitude of low-frequency fluctuation (fALFF) and voxel-mirrored homotopic connectivity (VMHC) and evaluate the correlation between abnormal regions in the brain and clinical features to investigate the pathogenesis of PPPD...
April 16, 2024: Brain Connectivity
https://read.qxmd.com/read/38622591/a-ph-responsive-nanoplatform-with-dual-modality-imaging-for-enhanced-cancer-phototherapy-and-diagnosis-of-lung-metastasis
#16
JOURNAL ARTICLE
Mujie Yuan, Zeyu Han, Yan Li, Xin Zhan, Yong Sun, Bin He, Yan Liang, Kui Luo, Fan Li
To address the limitations of traditional photothermal therapy (PTT)/ photodynamic therapy (PDT) and real-time cancer metastasis detection, a pH-responsive nanoplatform (NP) with dual-modality imaging capability was rationally designed. Herein, 1 H,1 H-undecafluorohexylamine (PFC), served as both an oxygen carrier and a 19 F magnetic resonance imaging (MRI) probe, and photosensitizer indocyanine green (ICG) were grafted onto the pH-responsive peptide hexahistidine (H6 ) to form H6 -PFC-ICG (HPI). Subsequently, the heat shock protein 90 inhibitor, gambogic acid (GA), was incorporated into hyaluronic acid (HA) modified HPI (HHPI), yielding the ultimate HHPI@GA NPs...
April 15, 2024: Journal of Nanobiotechnology
https://read.qxmd.com/read/38614154/pulmonary-hypertension-impairs-vasomotor-function-in-rat-diaphragm-arterioles
#17
JOURNAL ARTICLE
Kiana M Schulze, Andrew G Horn, Judy M Muller-Delp, Zachary J White, Stephanie E Hall, Steven L Medarev, Ramona E Weber, David C Poole, Timothy I Musch, Bradley J Behnke
Pulmonary hypertension (PH) is a chronic, progressive condition in which respiratory muscle dysfunction is a primary contributor to exercise intolerance and dyspnea in patients. Contractile function, blood flow distribution, and the hyperemic response are altered in the diaphragm with PH, and we sought to determine whether this may be attributed, in part, to impaired vasoreactivity of the resistance vasculature. We hypothesized that there would be blunted endothelium-dependent vasodilation and impaired myogenic responsiveness in arterioles from the diaphragm of PH rats...
April 11, 2024: Microvascular Research
https://read.qxmd.com/read/38613052/a-novel-tetrapeptide-ala-phe-phe-pro-affp-derived-from-antarctic-krill-prevents-scopolamine-induced-memory-disorder-by-balancing-lipid-metabolism-of-mice-hippocampus
#18
JOURNAL ARTICLE
Jingqi Yang, Yan Qi, Beiwei Zhu, Songyi Lin
Memory impairment is a serious problem with organismal aging and increased social pressure. The tetrapeptide Ala-Phe-Phe-Pro (AFFP) is a synthetic analogue of Antarctic krill derived from the memory-improving Antarctic krill peptide Ser-Ser-Asp-Ala-Phe-Phe-Pro-Phe-Arg (SSDAFFPFR) after digestion and absorption. The objective of this research was to assess the neuroprotective effects of AFFP by reducing oxidative stress and controlling lipid metabolism in the brains of mice with memory impairment caused by scopolamine...
March 31, 2024: Nutrients
https://read.qxmd.com/read/38610042/bacteria-driven-nanosonosensitizer-delivery-system-for-enhanced-breast-cancer-treatment-through-sonodynamic-therapy-induced-immunogenic-cell-death
#19
JOURNAL ARTICLE
Meng Du, Ting Wang, Wangrui Peng, Renjie Feng, MeeiChyn Goh, Zhiyi Chen
BACKGROUND: Sonodynamic therapy (SDT) has shown promise as a non-invasive cancer treatment due to its local effects and excellent tissue penetration. However, the limited accumulation of sonosensitizers at the tumor site hinders its therapeutic efficacy. Although nanosonosensitizers have improved local tumor accumulation through passive targeting via the enhanced permeability and retention effect (EPR), achieving sufficient accumulation and penetration into tumors remains challenging due to tumor heterogeneity and inaccurate targeting...
April 12, 2024: Journal of Nanobiotechnology
https://read.qxmd.com/read/38607956/polymetal-chelated-fabrication-of-bimetallic-nanophosphides-as-electrocatalysts-for-zinc-air-batteries
#20
JOURNAL ARTICLE
Xuan-Wen Gao, Jian-Jia Mu, Ran Wei, Xue Wang, Qinfen Gu, Lu-Kang Zhao, Wen-Bin Luo
Bimetallic phosphides are considered as promising electrocatalysts for zinc-air batteries toward oxygen evolution reaction (OER) and oxygen reduction reaction (ORR). To address the semi-conductor inherent low electronic conductivity and catalytic activity, a polymetal-chelated strategy is employed to in situ fabricate bimetallic nanophosphides within carbon matrix anchoring by chemical bonding. The employment of biomolecule polydopamine (PDA) efficiently anchors various transition metal ions due to its strong chelating capability via inherent functional groups...
April 12, 2024: Small Methods
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