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https://www.readbyqxmd.com/read/29241089/association-of-psychosis-with-antiphospholipid-antibody-syndrome-a-systematic-review-of-clinical-studies
#1
Asma Hallab, Sadiq Naveed, Ahmed Altibi, Mariam Abdelkhalek, Huyen Thi Ngo, Thao Phuong Le, Kenji Hirayama, Nguyen Tien Huy
OBJECTIVE: In this systematic review, we reviewed the association between Antiphospholipid antibody syndrome (APS) and psychosis and focused on the prevalence, clinical presentation, immunologic and neurological workup, treatment options, and clinical outcomes. METHODOLOGY: We performed this systematic review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)'s guidelines. We searched eight databases for potential articles and manually searched references and relevant articles of included studies...
November 16, 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/29240853/the-evaluation-of-medical-inpatients-who-are-admitted-on-long-term-opioid-therapy-for-chronic-pain
#2
Hilary Mosher, Shoshana J Herzig, Itai Danovitch, Christina Boutsicaris, Sameer Hassamal, Karl Wittnebel, Azadeh Dashti, Teryl Nuckols
Individuals who are on long-term opioid therapy (LTOT) for chronic noncancer pain are frequently admitted to the hospital with acute pain, exacerbations of chronic pain, or comorbidities. Consequently, hospitalists find themselves faced with complex treatment decisions in the context of uncertainty about the effectiveness of LTOT as well as concerns about risks of overdose, opioid use disorders, and adverse events. Our multidisciplinary team sought to synthesize guideline recommendations and primary literature relevant to assessing medical inpatients on LTOT, with the objective of assisting practitioners in balancing effective pain treatment and opioid risk reduction...
December 6, 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29240741/a-retrospective-audit-of-the-characteristics-and-treatment-outcomes-in-patients-with-diabetes-related-charcot-neuropathic-osteoarthropathy
#3
Joanne Dixon, Joshua Coulter, Michele Garrett, Rick Cutfield
AIMS: To review the characteristics, management and outcomes one year after diagnosis in patients with diabetes related charcot neuropathic osteoarthropathy (CN) treated at the Diabetes Podiatry service, Waitemata District Health Board (WDHB) between 2000-2014. METHODS: Patients with diabetes and recorded diagnosis of CN were identified from the podiatry service records. Clinical details were retrospectively obtained from WDHB databases and patient medical records...
December 15, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29240035/acinic-cell-carcinoma-of-the-parotid-gland-in-children-and-adolescents
#4
Shifra Ash, Isaac Yaniv, Raphael Feinmesser, Osnat Konen, Meora Feinmesser
Acinic cell carcinoma of the parotid gland is a rare low-grade malignant neoplasm. Data on children are sparse. For the present study, the database of a tertiary pediatric medical center was reviewed for all patients with parotid gland acinic cell carcinoma diagnosed and treated between 2004 and 2013. Clinical, histologic, treatment, and outcome parameters were collected from the medical files. Four patients were identified, 3 female and 1 male, aged 13.5 to 18 years (median 15.7) at diagnosis. One patient had a family history of parotid tumor and 1 of hypothyroidism/hyperthyroidism...
December 12, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29239865/large-databases-for-pediatric-research-on-children-with-autism-spectrum-disorder
#5
Karen A Kuhlthau, L Charles Bailey, Briella L Baer, Daniel L Coury, J Kiely Law, Donna S Murray, Hanieh Razzaghi, Christopher B Forrest, Paul H Lipkin
OBJECTIVE: This article reviews the data available in 3 large databases for use in conducting studies of children with autism spectrum disorder (ASD). METHODS: The article describes the data structure, data elements, and strengths and weaknesses of the 3 data sets. RESULTS: Each of the 3 data sets, the Interactive Autism Network (IAN), the Autism Treatment Network (ATN), and PEDSnet have large cohorts of children with ASD. IAN has strengths in patient-reported measures, ATN in clinical characterization, and PEDSnet in health care encounters and electronic medical record data...
December 11, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29239753/the-use-of-intranasal-analgesia-for-acute-pain-control-in-the-emergency-department-a-literature-review
#6
REVIEW
Billy Sin, Jennifer Wiafe, Christine Ciaramella, Luis Valdez, Sergey M Motov
BACKGROUND: Traditional routes for administration of pain medications include oral (PO), intravenous (IV), or intramuscular routes (IM). When these routes are not feasible, the intranasal (IN) route may be considered. The objectives of this evidence-based review were: to review the literature which compared the safety and efficacy of IN analgesia to traditional routes and to determine if IN analgesia should be considered over traditional routes for acute pain control in the ED. METHODS: The MEDLINE and EMBASE databases from July 1970 to July 2017 were searched...
November 20, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29239630/a-meta-analytic-review-of-two-modes-of-learning-and-the-description-experience-gap
#7
Dirk U Wulff, Max Mergenthaler-Canseco, Ralph Hertwig
People can learn about the probabilistic consequences of their actions in two ways: One is by consulting descriptions of an action's consequences and probabilities (e.g., reading up on a medication's side effects). The other is by personally experiencing the probabilistic consequences of an action (e.g., beta testing software). In principle, people taking each route can reach analogous states of knowledge and consequently make analogous decisions. In the last dozen years, however, research has demonstrated systematic discrepancies between description- and experienced-based choices...
December 14, 2017: Psychological Bulletin
https://www.readbyqxmd.com/read/29239621/a-qualitative-analysis-of-gabapentin-misuse-and-diversion-among-people-who-use-drugs-in-appalachian-kentucky
#8
Rachel Vickers Smith, Elaine M Boland, April M Young, Michelle R Lofwall, Alexa Quiroz, Michele Staton, Jennifer R Havens
Gabapentin, an anticonvulsant and analgesic for postherpetic neuralgia, has been thought to have no abuse potential despite numerous published reports to the contrary. Gabapentin has been linked with impaired driving and opioid use, highlighting the need to more fully understand its risk profile. Thirty-three individuals reporting recent nonmedical use of gabapentin were recruited from two ongoing longitudinal studies of drug users in Appalachian Kentucky to participate in focus groups. Four sessions were held (two in the community and two in jail settings), during which participants responded to questions regarding their personal experiences with gabapentin misuse...
December 14, 2017: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
https://www.readbyqxmd.com/read/29239196/clinical-experience-of-positron-emission-tomography-in-infective-aortic-disease
#9
Julian S Tsang, Yiu Che Chan, Yuk Law, Stephen W Cheng
Background Fluorine-18-fluorodeoxyglucose positron-emission tomography with computed tomography has revolutionized medical diagnosis by adding functional activity to anatomic imaging. We report our experience with this technique in patients with mycotic aortic pathology and aortic vascular graft infection. Methods We conducted a retrospective review of a prospective database of patients who underwent 18F-fluorodeoxyglucose positron-emission tomography with computed tomography for suspected infective aortic disease...
January 1, 2017: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/29238799/association-of-clinical-dermoscopic-and-histopathologic-findings-with-gene-expression-in-patients-with-balloon-cell-melanoma
#10
Ben J Friedman, Rebecca Stoner, Joya Sahu, Jason B Lee
Importance: Balloon cell melanoma is a rare subtype of melanoma that is underrecognized clinically and is challenging to diagnose on histologic studies. Objective: To further characterize the clinical, dermoscopic, and histopathologic features of balloon cell melanomas and their correlation to gene expression. Design, Setting, and Participants: Case series of 2 patients with balloon cell melanoma whose medical records were retrieved from the database of Thomas Jefferson University Dermatopathology Center in Philadelphia, Pennsylvania...
December 13, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/29238730/interaction-of-pubertal-development-and-metabolic-control-in-adolescents-with-type-1-diabetes-mellitus
#11
M Plamper, B Gohlke, J Woelfle, K Konrad, T Rohrer, S Hofer, W Bonfig, K Fink, R W Holl
Background: In T1DM, delayed pubertal development and reduced final height are associated with inadequate metabolic control. Objective: To assess whether T1DM affects pubertal growth spurt and whether metabolic control during puberty is gender-related. Methods: Using a large multicentre database, longitudinal data from 1294 patients were analysed. Inclusion criteria: complete records of height and HbA1c from the age of seven to 16 years. Exclusion criteria: other significant chronic diseases and medications, T1DM duration less than three months, and initial BMI < 3rd or >97th percentile...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/29238663/prevention-identification-and-management-of-post-operative-penile-implant-complications-of-infection-hematoma-and-device-malfunction
#12
REVIEW
Timothy K O'Rourke, Alexander Erbella, Yu Zhang, Matthew S Wosnitzer
Penile prosthesis implant surgery is an effective management approach for a number of urological conditions, including medication refractory erectile dysfunction (ED). Complications encountered post-operatively include infection, bleeding/hematoma, and device malfunction. Since the 1970s, modifications to these devices have reduced complication rates through improvement in antisepsis and design using antibiotic coatings, kink-resistant tubing, lock-out valves to prevent autoinflation, and modified reservoir shapes...
November 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29238635/anesthesia-duration-as-an-independent-risk-factor-for-early-postoperative-complications-in-adults-undergoing-elective-acdf
#13
Kevin Phan, Jun S Kim, Joung Heon Kim, Sulaiman Somani, John Di'Capua, James E Dowdell, Samuel K Cho
Study Design: Retrospective study. Objective: To determine the presence of any potential associations between anesthesia time with postoperative outcome and complications following elective anterior cervical discectomy and fusion (ACDF). Methods: Patients who underwent elective ACDF were identified in the American College of Surgeons National Quality Improvement Program database. Patient demographics, medical comorbidities, and perioperative and postoperative complications up to 30 days were analyzed by univariate and multivariate analysis...
December 2017: Global Spine Journal
https://www.readbyqxmd.com/read/29238479/vitamin-d-receptor-gene-polymorphisms-as-a-risk-factor-for-obesity-in-saudi-men
#14
Ayman Saeed Al-Hazmi, Mazin Mohammed Al-Mehmadi, Sarah Mohammad Al-Bogami, Ashjan Ali Shami, Ahmed Ali Al-Askary, Anas Mohammad Alomery, Saad Saeed Al-Shehri, Haytham Dahlawi, Khadija Abdulrazag, Tariq Ali, Abdalaziz Al-Bogami, Emad Sheshah, Abdalaziz Al-Mutairi, Salh Al-Suhimi, Faris Alharb
Background: The prevalence of obesity and vitamin D deficiency in Saudi Arabia has increased recently. Decreased physical activity might play a role in obesity. Previous studies showed an association between low vitamin D level and its receptor polymorphism with obesity development. Objective: To determine association of low vitamin D level and its receptor polymorphism with obesity in Saudi men. Methods: This case control study was carried out from March 2016 through March 2017...
October 2017: Electronic Physician
https://www.readbyqxmd.com/read/29238462/mechanisms-of-spinal-cord-injury-regeneration-in-zebrafish-a-systematic-review
#15
REVIEW
Zeynab Noorimotlagh, Mahla Babaie, Mahdi Safdarian, Tahereh Ghadiri, Vafa Rahimi-Movaghar
Objectives: To determine the molecular and cellular mechanisms of spinal cord regeneration in zebrafish. Materials and Methods: Medical databases of PubMed and Scopus were searched with following key words: Zebrafish; spinal cord injuries; regeneration; recovery of function. The map of mechanisms was performed using Xmind software. Results: Wnt/ß-catenin signaling, L1.1, L1.2, Major vault protein (MVP), contactin-2 and High mobility group box1 (HMGB1) had positive promoting effects on axonal re-growth while Ptena had an inhibitory effect...
December 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/29238392/risk-for-depression-burnout-and-low-quality-of-life-among-personnel-of-a-university-hospital-in-italy-is-a-consequence-of-the-impact-one-economic-crisis-in-the-welfare-system
#16
M G Carta, A Preti, I Portoghese, E Pisanu, D Moro, M Pintus, E Pintus, A Perra, S D'Oca, M Atzeni, M Campagna, E Fabrici Pascolo, F Sancassiani, G Finco, E D'Aloja, L Grassi
Background: Research literature suggests that burnout, depression, and a low mental quality of life (QOL) are common among health care workers. Economic crisis might have increased the burden of burnout, depression and low QOL in health care workers. Objectives: To identify depression risk, burnout levels, and quality of life in a sample of workers of an Italian university hospital. Method: Cross sectional study with comparison with two community surveys database results (n = 2000 and 1500, respectively)...
2017: Clinical Practice and Epidemiology in Mental Health: CP & EMH
https://www.readbyqxmd.com/read/29238240/the-effect-of-dpp-4-inhibitors-on-asthma-control-an-administrative-database-study-to-evaluate-a-potential-pathophysiological-relationship
#17
Gene Colice, David Price, Maria Gerhardsson de Verdier, Karma Rabon-Stith, Christopher Ambrose, Katherine Cappell, Debra E Irwin, Paul Juneau, Anna Vlahiotis
Rationale: DPP-4 may regulate immunological pathways implicated in asthma. Assessing whether DPP-4 inhibitor (DPP-4i) use might affect asthma control is clinically important because DPP-4i use in type 2 diabetes mellitus management (T2DM) is increasing. This study evaluated associations between DPP-4i use and asthma control. Methods: This was a retrospective, observational, matched cohort study using administrative claims in the MarketScan® Commercial Claims and Encounters (Commercial) and Medicare Supplemental and Coordination of Benefits (Medicare Supplemental) databases...
2017: Pragmatic and Observational Research
https://www.readbyqxmd.com/read/29238212/effects-of-an-antimicrobial-restriction-system-on-appropriate-carbapenem-use-in-a-hospital-without-infectious-diseases-consultation
#18
Warangkhana Wanla, Wasan Katip, Sakon Supakul, Porntipa Apiwatnakorn, Sompong Khamsarn
Background: Gram-negative bacteria are becoming increasingly resistant to carbapenems and are related to the use of carbapenems. Thus, the main objective of this study was to compare the appropriateness of prescribing carbapenem before and after using an antimicrobial restriction system without infectious diseases consultation. Materials and methods: A retrospective cross-sectional before and after study was conducted in Lamphun Hospital to limit the prescription of carbapenems...
2017: International Journal of General Medicine
https://www.readbyqxmd.com/read/29237929/contralateral-c7-nerve-root-transfer-for-function-recovery-in-adults-a-meta-analysis
#19
Wen-Jun Li, Li-Yue He, Shan-Lin Chen, Yan-Wei Lyu, Shu-Feng Wang, Yang Yong, Wen Tian, Guang-Lei Tian, Yu-Dong Gu
BACKGROUND: Root avulsion to all 5 roots of the brachial plexus is a common presentation and keeps a major reconstructive challenge. The contralateral C7 (CC7) nerve transfer has been used in treating brachial plexus avulsion injury (BPAI) since 1986. However, the effectiveness of the procedure remains a subject of controversy. The aim of this meta-analysis was to study surgical outcomes regarding motor and sensory recovery after CC7 nerve transfer. METHODS: Chinese or English (i...
December 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/29237436/high-flow-nasal-cannula-oxygen-therapy-versus-conventional-oxygen-therapy-in-patients-with-acute-respiratory-failure-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#20
Youfeng Zhu, Haiyan Yin, Rui Zhang, Jianrui Wei
BACKGROUND: Acute respiratory failure (ARF) is a common and life-threatening medical emergency in patients admitted to the hospital. Currently, there is a lack of large-scale evidence on the use of high-flow nasal cannulas (HFNC) in patients with ARF. In this systematic review and meta-analysis, we evaluated whether there were differences between HFNC therapy and conventional oxygen therapy (COT) for treating patients with ARF. METHODS: The EMBASE, Medline, and Wanfang databases and the Cochrane Library were searched...
December 13, 2017: BMC Pulmonary Medicine
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