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https://www.readbyqxmd.com/read/29353157/phytochemical-analysis-of-salal-berry-gaultheria-shallon-pursh-a-traditionally-consumed-fruit-from-western-north-america-with-exceptionally-high-proanthocyanidin-content
#1
Andrew Ferguson, Elisabete Carvalho, Geraldine Gourlay, Vincent Walker, Stefan Martens, Juha-Pekka Salminen, C Peter Constabel
Salal (Gaultheria shallon Pursh.) is a wild perennial shrub of the Ericaceae and common in coastal forests of western North America, and its berries were an important traditional food for First Nations in British Columbia. Salal berries were investigated for phytochemical content and antioxidant capacity over the course of fruit development. The proanthocyanidin content was extremely high in young berries (280.7 mg/g dry wt) but dropped during development to 52.8 mg/g dry wt. By contrast, anthocyanins accumulated only at the late berry stages...
January 17, 2018: Phytochemistry
https://www.readbyqxmd.com/read/29353020/ultrasound-improves-antimicrobial-effect-of-sodium-dichloroisocyanurate-to-reduce-salmonella-typhimurium-on-purple-cabbage
#2
Ana Lúcia Almeida Duarte, Denes Kaic Alves do Rosário, Syllas Borburema Silva Oliveira, Hygor Lendell Silva de Souza, Raquel Vieira de Carvalho, Joel Camilo Souza Carneiro, Pollyanna Ibrahim Silva, Patrícia Campos Bernardes
The consumer's interest in ready-to-eat, fast-ready, nutritious and fresh foods is a major challenge for the food industry. Thus, studies on new sanitization methods are relevant. The effect of Sodium Hypochlorite (SH), Benzalkonium Chloride (BC), and Sodium Dichloroisocyanurate (SD) isolated or combined with Ultrasound (US) in purple cabbage quality over 7 days of storage at 8 ± 1 °C was evaluated. The natural microbiota (mesophilic aerobic bacteria, lactic acid bacteria and coliforms), intentionally inoculated Salmonella Typhimurium, physicochemical quality (anthocyanins, pH, total titratable acidity, instrumental color and mass loss) and sensorial quality (multiple comparison test and visual sensory acceptance) were analyzed...
January 8, 2018: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29351247/b-type-and-complex-a-b-type-epicatechin-trimers-isolated-from-litchi-pericarp-aqueous-extract-show-high-antioxidant-and-anticancer-activity
#3
Yihui Gong, Fang Fang, Xin Zhang, Bin Liu, Honghui Luo, Zhen Li, Xuelian Zhang, Zhaoqi Zhang, Xuequn Pang
Litchi (Litchi chinensis Sonn.) fruit is known for its rich source of phenolics. Litchi pericarp contains high levels of epicatechin that may form oligomers of various lengths. Except for several A or B type epicatechin dimers, other soluble oligomers have rarely been identified in the pericarp. Here, bioassay-guided column fractionation was applied to isolate bioactive phenolics from aqueous pericarp extract. A fraction (S3) was obtained by two rounds of Sephadex LH-20 column chromatography, and showed higher antioxidant activity and inhibition on the proliferation of human lung cancer cells (A549) than Litchi anthocyanins...
January 19, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29350256/analysis-of-phenolic-compounds-in-different-parts-of-pomegranate-punica-granatum-fruit-by-hplc-pda-esi-ms-and-evaluation-of-their-antioxidant-activity-application-to-different-italian-varieties
#4
Marina Russo, Chiara Fanali, Giusy Tripodo, Paola Dugo, Rosario Muleo, Laura Dugo, Laura De Gara, Luigi Mondello
The analysis of pomegranate phenolic compounds belonging to different classes in different fruit parts was performed by high-performance liquid chromatography coupled with photodiode array and mass spectrometry detection. Two different separation methods were optimized for the analysis of anthocyanins and hydrolyzable tannins along with phenolic acids and flavonoids. Two C18 columns, core-shell and fully porous particle stationary phases, were used. The parameters for separation of phenolic compounds were optimized considering chromatographic resolution and analysis time...
January 19, 2018: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29345498/effects-of-blueberry-and-cranberry-consumption-on-type-2-diabetes-glycemic-control-a-systematic-review
#5
Dmup Rocha, Aps Caldas, Bp da Silva, Hh Hermsdorff, Rcg Alfenas
The metabolic effects of cranberry and blueberry consumption on glycemic control have been evaluated in vitro and in animal models as well as in human studies, although findings have not been systematically reviewed yet. Therefore, a systematic review was carried out of relevant randomized clinical trials (RCTs) in order to assess the effect of berries (blueberry and cranberry) consumption on type 2 diabetes (T2DM) glycemic control. Some evidences were also discussed on the anti-diabetic mechanisms exerted by berries polyphenols...
January 18, 2018: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29344660/purple-sweet-potato-color-attenuates-high-fat-induced-neuroinflammation-in-mouse-brain-by-inhibiting-mapk-and-nf-%C3%AE%C2%BAb-activation
#6
Jian Li, Zhao Shi, Yongjie Mi
Purple sweet potato color (PSPC) is a natural anthocyanin pigment that is derived from purple sweet potato storage roots. PSPC possesses a variety of biological activities, including antioxidant, anti‑inflammatory and neuroprotective effects; however, the detailed effects of PSPC on high‑fat diet (HFD)‑induced neuroinflammation remain to be determined. The aim of the present study was to investigate whether PSPC has a protective role in HFD‑associated neuroinflammation in the mouse brain and to provide novel insight into the mechanisms of the action...
January 17, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29344587/an-exploratory-study-of-red-raspberry-rubus-idaeus-l-poly-phenols-metabolites-in-human-biological-samples
#7
Xuhuiqun Zhang, Amandeep Sandhu, Indika Edirisinghe, Britt Burton-Freeman
Red raspberry (Rubus idaeus L.) contains a variety of polyphenols including anthocyanins and ellagitannins. Red raspberry polyphenols absorbed in different forms (parent compounds, degradants or microbial metabolites) are subject to xenobiotic metabolism in the intestine, liver, and/or kidney, forming methylate, glucuronide, and sulfate conjugated metabolites. Upon acute exposure, (poly)phenol/metabolite presence in the blood depends mainly on intestinal absorption, enterohepatic circulation, and metabolism by resident microbiota...
January 18, 2018: Food & Function
https://www.readbyqxmd.com/read/29343201/the-impact-of-blackcurrant-juice-on-attention-mood-and-brain-wave-spectral-activity-in-young-healthy-volunteers
#8
A W Watson, E J Okello, H J Brooker, S Lester, G J McDougall, K A Wesnes
There is a growing body of evidence from randomized controlled trials which indicates that consumption of berries has a positive effect upon the cognitive function of healthy adults. It has been recommended that studies combining cognitive and physiological measures be undertaken in order to strengthen the evidence base for the putative effects of flavonoid consumption on cognitive outcomes. This pilot study utilized a randomized, double-blind and placebo controlled crossover design to assess the influence of the acute administration of anthocyanin-rich blackcurrant juice, standardized at 500 mg of polyphenols, on mood and attention...
January 17, 2018: Nutritional Neuroscience
https://www.readbyqxmd.com/read/29338343/molecular-analysis-of-anthocyanin-biosynthesis-pathway-genes-and-their-differential-expression-in-mango-peel
#9
Anju Bajpai, Kasim Khan, M Muthukumar, S Rajan, Nagendra Kumar Singh
Mango fruit is cherished by masses for its taste and nutrition, contributed by color, flavor and aroma. Among these, peel color is an important trait contributing to fruit quality and market value. We attempted to elucidate the role of key genes of anthocyanin biosynthesis pathway related to fruit peel color from the leaf transcriptome of cv. Amrapali. A total of 108 mined transcript sequences were assigned to phenylpropanoid flavonoid pathway from which 15 contigs representing anthocyanin biosynthesis genes were annotated...
January 16, 2018: Genome Génome / Conseil National de Recherches Canada
https://www.readbyqxmd.com/read/29337409/engineering-of-purple-embryo-maize-with-a-multigene-expression-system-derived-from-a-bidirectional-promoter-and-self-cleaving-2a-peptides
#10
Xiaoqing Liu, Wenzhu Yang, Bona Mu, Suzhen Li, Ye Li, Xiaojin Zhou, Chunyi Zhang, Yunliu Fan, Rumei Chen
Anthocyanins are polyhydroxy and polymethoxy 2-phenylbenzopyrylium glucosides that belong to a large group of plant secondary metabolites termed flavonoids. The most common anthocyanidins (anthocyanin aglycones) in higher plants are cyanidin, pelargonidin, peonidin, delphinidin, petunidin and malvidin. Flavonoid biosynthesis has been suggested to occur on the cytoplasmic face of the endoplasmic reticulum (ER), where sequential enzymes of the pathway loosely form a metabolon (Winkel-Shirley, 1999). Known structural genes along the anthocyanin biosynthesis pathway in maize include chalcone synthase (CHS), chalcone isomerase (CHI), flavanone 3-hydroxylase (F3H), flavonoid 3'-hydroxylase (F3'H), dihydroflavonol 4-reductase (DFR), anthocyanidin synthase (ANS), flavonoid 3-O-glucosyltransferase (3UFGT) and glutathione S-transferase (GST)...
January 16, 2018: Plant Biotechnology Journal
https://www.readbyqxmd.com/read/29337349/phytochemicals-anti-inflammatory-antiproliferative-and-methylglyoxal-trapping-properties-of-zijuan-tea
#11
Xiong Gao, Chi-Tang Ho, Xiaofei Li, Xiaorong Lin, Yuanyuan Zhang, Zhongzheng Chen, Bin Li
Zijuan tea (Camellia sinensis var. assamica) is a unique anthocyanin-rich tea cultivar in China. Although chemical component analysis of Zijuan tea and extraction technology of anthocyanins was widely documented, its functional properties have not been extensively explored. In this study, the anti-inflammatory, antiproliferative, and methylglyoxal (MGO) trapping activities of water extract (ZWE) and ethyl acetate extract (ZEE) of Zijuan tea were investigated for the 1st time. Results showed that ZWE and ZEE exhibited inhibitory effects on nitric oxide (NO), tumor necrosis factor (TNF)-α, and interleukin (IL)-6 production as well as inducible nitric oxide synthase protein (iNOS) expression in lipopolysaccharide (LPS)-induced RAW 264...
January 16, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29336479/inhibition-of-glycolytic-metabolism-in-glioblastoma-cells-by-pt3glc-combinated-with-pi3k-inhibitor-via-sirt3-mediated-mitochondrial-and-pi3k-akt-mapk-pathway
#12
Gang Wang, Xing-Li Fu, Jun-Jie Wang, Rui Guan, Yan Sun, Shing-Shun Tony To
Glioblastoma multiforme (GBM) is the most malignant and aggressive glioma with abnormal expression of genes that mediate glycolytic metabolism and tumor cell growth. Petunidin-3-O- glucoside (Pt3glc) is a kind of anthocyanin in the red grape and derived beverages, representing the most common naturally occurring anthocyanins with a reduced incidence of cancer and heart diseases. In this study, whether Pt3glc could effectively regulate glycolysis to inhibit GBM cell was investigated by using the DBTRG-05MG cell lines...
January 16, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29335878/antioxidant-compounds-recovery-from-ju%C3%A3-ara-residue-by-thermal-assisted-extraction
#13
Leilson O Ribeiro, Ricardo N C Pereira, Renata V Tonon, Lourdes Maria C Cabral, Manuela Cristina P A Santiago, António A Vicente, José António C Teixeira, Virgínia M Matta, Suely P Freitas
This study aimed to recover bioactive compounds by solid-liquid extraction from the agro-industrial residue obtained during juçara fruits processing into pulp. A preliminary study using different solvents (methanol, ethanol and water) indicated ethanol in aqueous solution as the best solvent for antioxidants recovery. Then, a Box-Behnken design was applied considering as independent variables the solvent composition (30-70% ethanol in water), temperature (30-70 °C) and time (30-60 min), in order to evaluate the effects of these factors on antioxidant activity in juçara extract...
January 15, 2018: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/29333856/analysis-of-the-ph-dependent-fe-iii-ion-chelating-activity-of-anthocyanin-extracted-from-black-soybean-glycine-max-l-merr-coats
#14
Yanli Xie, Xiaolu Zhu, Yuan Li, Cheng Wang
The Fe(III) chelating activity of anthocyanin extracted from black soybean coats was investigated at pH 3.0, 5.0, 6.5, 7.0 and 7.4 with fluorescence spectroscopy and microscale thermophoresis (MST). Cyanidin-3-glucoside (C3G) was determined to be 98% of the total anthocyanin by HPLC. The binding affinity (Ka) exhibited significant pH-dependent behavior; Ka was 9.7167, 1.0837, 1.4284, 5.4550 and 3.0269×104 M-1 at pH 3.0, 5.0, 6.5, 7.0 and 7.4, respectively (p<0.05). The MST data showed that ΔG<0 and ΔH<0, demonstrating that chelation is spontaneous and exothermic...
January 15, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29333387/physicochemical-and-antioxidant-properties-of-honeys-from-the-sundarbans-mangrove-forest-of-bangladesh
#15
M Rabiul Islam, Tahmina Pervin, Hemayet Hossain, Badhan Saha, Sheikh Julfikar Hossain
This study evaluated the physicochemical, nutritional, antioxidant, and phenolic properties of ten honey samples from the Sundarbans mangrove forest, Bangladesh. The average pH, electrical conductivity, total dissolved solid, ash, moisture, hydroxymethyl furfural, titrable acidity, and absorbance were 4.3, 0.38 mS/cm, 187.5 ppm, 0.14%, 17.88%, 4.4 mg/kg, 37.7 meq/kg, and 483 mAU, respectively. In the honeys, the average contents of Ca, Cu, Fe, K, Mg, Mn, and Na were 95.5, 0.19, 6.4, 302, 39.9, 3.4, and 597 ppm, respectively, whereas Cd, Cr, Pb, and Ni were not found...
December 2017: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/29332189/the-arabidopsis-histone-chaperone-fact-is-required-for-stress-induced-expression-of-anthocyanin-biosynthetic-genes
#16
Alexander Pfab, Matthias Breindl, Klaus D Grasser
The histone chaperone FACT is involved in the expression of genes encoding anthocyanin biosynthetic enzymes also upon induction by moderate high-light and therefore contributes to the stress-induced plant pigmentation. The histone chaperone FACT consists of the SSRP1 and SPT16 proteins and associates with transcribing RNAPII (RNAPII) along the transcribed region of genes. FACT can promote transcriptional elongation by destabilising nucleosomes in the path of RNA polymerase II, thereby facilitating efficient transcription of chromatin templates...
January 13, 2018: Plant Molecular Biology
https://www.readbyqxmd.com/read/29332168/efficient-crispr-cas9-based-genome-editing-in-carrot-cells
#17
Magdalena Klimek-Chodacka, Tomasz Oleszkiewicz, Levi G Lowder, Yiping Qi, Rafal Baranski
The first report presenting successful and efficient carrot genome editing using CRISPR/Cas9 system. Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated (Cas9) is a powerful genome editing tool that has been widely adopted in model organisms recently, but has not been used in carrot-a model species for in vitro culture studies and an important health-promoting crop grown worldwide. In this study, for the first time, we report application of the CRISPR/Cas9 system for efficient targeted mutagenesis of the carrot genome...
January 13, 2018: Plant Cell Reports
https://www.readbyqxmd.com/read/29331904/anthocyanins-in-perilla-plants-and-dried-leaves
#18
Yumi Fujiwara, Miya Kono, Airi Ito, Michiho Ito
High-quality perilla leaves are purple on upper and lower surfaces and have a good aroma. The Japanese Pharmacopoeia specifies the content of essential oils in perilla leaves but not that of anthocyanins. Several reports have described the chemical species of anthocyanins in red perilla, but a complete analysis of anthocyanins in perilla has not been reported. In this study, the anthocyanins in the leaves of cultivated and wild species of perilla and those in commercially available perilla herbs were studied...
January 11, 2018: Phytochemistry
https://www.readbyqxmd.com/read/29331819/new-strategy-for-determination-of-anthocyanins-polyphenols-and-antioxidant-capacity-of-brassica-oleracea-liquid-extract-using-infrared-spectroscopies-and-multivariate-regression
#19
Isadora R N de Oliveira, Jussara V Roque, Mariza P Maia, Paulo C Stringheta, Reinaldo F Teófilo
A new method was developed to determine the antioxidant properties of red cabbage extract (Brassica oleracea) by mid (MID) and near (NIR) infrared spectroscopies and partial least squares (PLS) regression. A 70% (v/v) ethanolic extract of red cabbage was concentrated to 9° Brix and further diluted (12 to 100%) in water. The dilutions were used as external standards for the building of PLS models. For the first time, this strategy was applied for building multivariate regression models. Reference analyses and spectral data were obtained from diluted extracts...
January 4, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/29329847/encapsulation-of-anthocyanins-from-bilberries-effects-on-bioavailability-and-intestinal-accessibility-in-humans
#20
Dolores Mueller, Kathrin Jung, Manuel Winter, Dorothee Rogoll, Ralph Melcher, Ulrich Kulozik, Karin Schwarz, Elke Richling
Anthocyanins are flavonoids that have been suggested to provide beneficial health effects. The biological activity of anthocyanins is influenced by their pharmacokinetic properties, but anthocyanins are associated with limited bioavailability in humans. In the presented study, we investigated how the encapsulation of bilberry extract (BE), a source of anthocyanins, with either whey protein or citrus pectin influences the bioavailability and intestinal accessibility of anthocyanins in humans. We performed an intervention study that analyzed anthocyanins and their degradation products in the urine, plasma, and ileal effluent of healthy volunteers and ileostomists (subjects without an intact colon)...
May 15, 2018: Food Chemistry
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