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https://www.readbyqxmd.com/read/29776733/exploratory-study-of-the-course-of-posttraumatic-stress-disorder-after-aneurysmal-subarachnoid-hemorrhage
#1
Irene M C Huenges Wajer, Anouk R Smits, Gabriel J E Rinkel, Martine J E van Zandvoort, Leoniek Wijngaards-de Meij, Johanna M A Visser-Meily
OBJECTIVE: Posttraumatic stress disorder (PTSD) occurs often in aneurysmal subarachnoid hemorrhage (aSAH) survivors, but how PTSD develops over time post-aSAH is still unclear. We examined the course of PTSD symptoms during the first year after aSAH. METHOD: In this prospective cohort study, the Impact of Event Scale (IES) was applied in 128 patients 3, 6 and 12 months after aSAH. Multilevel modelling was used to assess changes in levels of PTSD symptoms over time and to explore if demographic characteristics, aSAH characteristics, level of education, cognitive functioning and neuroticism are associated to the course of PTSD symptoms...
May 9, 2018: General Hospital Psychiatry
https://www.readbyqxmd.com/read/29762759/measuring-the-impact-of-delayed-cerebral-ischemia-on-neuropsychological-outcome-after-aneurysmal-subarachnoid-hemorrhage-protocol-of-a-swiss-nationwide-observational-study-moca-dci-study
#2
Martin N Stienen, Christian Fung, Philippe Bijlenga, Daniel W Zumofen, Rodolfo Maduri, Thomas Robert, Martin A Seule, Serge Marbacher, Olivia Geisseler, Peter Brugger, Klemens Gutbrod, Christian Chicherio, Andreas U Monsch, Valérie Beaud, Stefania Rossi, Severin Früh, Nicole Schmid, Nicolas R Smoll, Emanuela Keller, Luca Regli
BACKGROUND: The exact relationship between delayed cerebral ischemia (DCI) following aneurysmal subarachnoid hemorrhage (aSAH) and neuropsychological impairment remains unknown, as previous studies lacked a baseline examination after aneurysm occlusion but before the DCI-period. Neuropsychological evaluation of acutely ill patients is often applied in a busy intensive care unit (ICU), where distraction represents a bias to the obtained results. OBJECTIVE: To evaluate the relationship between DCI and neuropsychological outcome after aSAH by comparing the Montreal Cognitive Assessment (MoCA) results in aSAH patients with and without DCI at 3 mo with a baseline examination before the DCI-period (part 1)...
May 11, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29760013/severity-of-cerebral-vasospasm-associated-with-development-of-collaterals-following-aneurysmal-subarachnoid-hemorrhage
#3
Fawaz Al-Mufti, Jens Witsch, Nathan Manning, Michael Crimmins, Krishna Amuluru, Sachin Agarwal, Soojin Park, Joshua Z Willey, Hooman Kamel, E Sander Connolly, Philip M Meyers, Jan Claassen
INTRODUCTION: Cerebral collateral circulation has been studied extensively in ischemic stroke where it has been shown to be a predictor of reperfusion, final infarct size, and outcome. Little is known about the significance of the collaterals in the setting of aneurysmal subarachnoid hemorrhage (aSAH). We sought to evaluate the effect of cerebral vasospasm on the development of cerebral collaterals following aneurysmal subarachnoid hemorrhage and the effects of the latter on delayed cerebral ischemia (DCI)...
May 14, 2018: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29749915/continuous-infusion-of-low-dose-unfractionated-heparin-after-aneurysmal-subarachnoid-hemorrhage-a-preliminary-study-of-cognitive-outcomes
#4
Robert F James, Nicolas K Khattar, Zaid S Aljuboori, Paul S Page, Elaine Y Shao, Lacey M Carter, Kimberly S Meyer, Michael W Daniels, John Craycroft, John R Gaughen, M Imran Chaudry, Shesh N Rai, D Erik Everhart, J Marc Simard
OBJECTIVE Cognitive dysfunction occurs in up to 70% of aneurysmal subarachnoid hemorrhage (aSAH) survivors. Low-dose intravenous heparin (LDIVH) infusion using the Maryland protocol was recently shown to reduce clinical vasospasm and vasospasm-related infarction. In this study, the Montreal Cognitive Assessment (MoCA) was used to evaluate cognitive changes in aSAH patients treated with the Maryland LDIVH protocol compared with controls. METHODS A retrospective analysis of all patients treated for aSAH between July 2009 and April 2014 was conducted...
May 11, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29741146/cognitive-outcomes-after-anterior-communicating-artery-aneurysm-repair
#5
Farshad Nassiri, Adriana M Workewych, Jetan H Badhiwala, Michael D Cusimano
Background The long-term cognitive and quality-of-life (QoL) outcomes after treatment of ruptured anterior communicating artery (ACoA) aneurysms are unknown. Methods Potential participants were all consecutive patients with ruptured ACoA aneurysms who were treated at one institution from July 1992 to December 2008. All potential participants were asked to complete the Cognitive Failures Questionnaire (CFQ), Center for Epidemiology Studies-Depression (CES-D) questionnaire, Short Form 36 (SF-36) questionnaire, and Telephone Interview for Cognitive Status-Modified (TICS-M)...
May 9, 2018: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29730271/intraventricular-extension-of-an-aneurysmal-subarachnoid-hemorrhage-is-an-independent-predictor-of-a-worse-functional-outcome
#6
Mario Zanaty, Daichi Nakagawa, Robert M Starke, Enrique C Leira, Edgar A Samaniego, Waldo R Guerrero, James Torner, Yasunori Nagahama, Olatilewa Awe, Jeremy Greenlee, Joseph S Hudson, Lauren Allan, Reem Elwy, Nohra Chalouhi, Pascal Jabbour, Royce Woodroffe, Anthony Piscopo, David Hasan
OBJECTIVE: The objective of this study is to determine the impact of intraventricular hemorrhage (IVH) on the cognitive prognosis of subarachnoid hemorrhage (SAH) due to ruptured cerebral aneurysm, independent of the presence of intraparenchymal hemorrhage, hydrocephalus or vasospasm. PATIENT AND METHODS: A Retrospective review of a prospectively collected database of patients with aneurysmal SAH from July 2009 to November 2016 was performed. Patients were included if they had a saccular aneurysm with a Hunt-Hess grade (HHG) 1-3...
April 30, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29694980/a-twelve-week-moderate-exercise-programme-improved-symptoms-of-depression-insomnia-and-verbal-learning-in-post-aneurysmal-subarachnoid-haemorrhage-patients-a-comparison-with-meningioma-patients-and-healthy-controls
#7
Flora Colledge, Serge Brand, Uwe Pühse, Edith Holsboer-Trachsler, Stefan Zimmerer, Ramona Schleith, Markus Gerber
OBJECTIVES: Deficits in psychological functioning, cognitive functioning, and sleep are frequently experienced by individuals who have survived aneurysmal subarachnoid haemorrhage (aSAH). Exercise has been shown to improve these domains; to date, it has never been explored in patients following aSAH. The aim of this exploratory study is to compare the effects of an exercise programme in this population with another patient group, and a group of healthy controls. METHODS: The present study explored the effects of 12 weeks of moderate aerobic exercise training on 15 aSAH patients, 16 meningioma patients, and 17 healthy controls...
April 25, 2018: Neuropsychobiology
https://www.readbyqxmd.com/read/29685515/cerebral-embolization-during-endovascular-infrarenal-juxtarenal-and-suprarenal-aortic-aneurysm-repair-high-risk-maneuvers-and-associated-neurologic-outcomes
#8
Ruth A Benson, David Matthews, Vanessa Loftus, Grainne Nicholson, David Tropman, Ian M Loftus
BACKGROUND: Risk factors for postoperative cognitive decline after noncardiac surgery are multifactorial and poorly understood. Evidence suggests that perioperative microembolic damage to the brain on movement of wires and catheters during endovascular aortic procedures may play an important role. Endovascular aortic aneurysm repair requires invasive manipulation of wires and cannulas within the aorta, but research into cerebral emboli during aortic aneurysm repair and cognitive or neurologic injury is scarce and limited to thoracic aneurysms...
April 20, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29676694/keyhole-strategy-aiming-at-minimizing-hospital-stay-for-surgical-clipping-of-unruptured-middle-cerebral-artery-aneurysms
#9
Kentaro Mori, Kojiro Wada, Naoki Otani, Arata Tomiyama, Terushige Toyooka, Satoru Takeuchi, Takuji Yamamoto, Yasuaki Nakao, Hajime Arai
OBJECTIVE Aneurysms of the middle cerebral artery (MCA) are still most often treated by clipping through standard craniotomy, but a longer hospital stay is one of the main drawbacks of this treatment. The authors developed a pterional keyhole clipping strategy for unruptured MCA aneurysms with the intention of minimizing hospital stay. In this paper, they report on their experience with this approach and analyze the long-term neurological and radiological outcomes. METHODS A total of 160 relatively small unruptured MCA aneurysms (mean 6...
April 20, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29673817/combined-outcomes-of-endovascular-or-surgical-treatment-of-unruptured-anterior-communicating-artery-aneurysms-is-a-more-aggressive-management-strategy-warranted
#10
Philip G R Schmalz, Alejandro Enriquez-Marulanda, Abdulrahman Alturki, Christopher J Stapleton, Ajith J Thomas, Christopher S Ogilvy
BACKGROUND: Updated natural history studies suggest anterior communicating artery aneurysms have a higher risk of rupture than formerly appreciated. As endovascular and open techniques advance, morbidity may fall to levels which suggest intervention even for small aneurysms. OBJECTIVE: Assess treatment risk for smaller, unruptured anterior communicating artery aneurysms. METHODS: A cross-sectional study of 149 patients with unruptured anterior communicating aneurysms treated over a six-year period was performed...
April 16, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29567870/-blister-like-aneurysm-originating-from-the-anterior-communicating-artery-a-case-report
#11
Tomohiro Abiko, Katsuya Saito, Makoto Murase, Hideyuki Tomita
Blister-like aneurysms(BLA)are morphologically thin-walled fragile structures that are associated with a high risk of intraoperative rupture. BLAs presumably originate from an arterial dissection and often stem from a non-branching site on the supraclinoid segment of the internal carotid artery. We report a rare case of a patient who was successfully treated for a ruptured BLA originating from the anterior communicating artery(Acom). A 60-year-old woman presented with severe headache and loss of consciousness...
March 2018: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/29548966/significant-injury-of-the-mammillothalamic-tract-without-injury-of-the-corticospinal-tract-after-aneurysmal-subarachnoid-hemorrhage-a-retrospective-diffusion-tensor-imaging-study
#12
Rami Darwazeh, Miao Wei, Jianjun Zhong, Zhaosi Zhang, Fajin Lv, Mazhar Darwazeh, Yi Guo, Yi Yan, Samer S Hoz, Xiaochuan Sun
OBJECTIVE: Little is known about the pathophysiologic mechanisms of white matter injury after aneurysmal subarachnoid hemorrhage (aSAH). The purpose of this study is to investigate whether the mammillothalamic tract (MTT) or corticospinal tract (CST) is more affected by aSAH in the same patients with good outcome (Grade 5 on Glasgow Outcome Scale at 3 months) using diffusion tensor imaging (DTI). METHODS: Between June 2013 and September 2016, 21 patients with aSAH with good outcome and 21 sex- and age-matched normal healthy control participants were recruited...
March 13, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29498974/successful-strategies-for-dealing-with-infected-custom-made-hydroxyapatite-cranioplasty
#13
Bruno Zanotti, Nicola Zingaretti, Angela Verlicchi, Alex Alfieri, Pier Camillo Parodi
When a cranioplasty implant becomes infected, standard operating procedure dictates its removal and the initiation of a long course of antibiotic therapy. However, removing such a prosthesis can have a series of adverse consequences, including delayed cognitive and motor recovery, lack of brain tissue protection, unsightly deformity, and the need for two additional surgical procedures, not to mention the additional costs involved. To maintain the advantages of cranioplasty, we opted for a conservative approach (levofloxacin and rifampicin every 24 hours for 8 weeks) in a 68-year-old woman whose custom-made porous hydroxyapatite implant, fitted following aneurysm clipping, had become infected...
March 1, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29498579/functional-outcomes-and-quality-of-life-after-microsurgical-clipping-of-unruptured-intracranial-aneurysms-a-prospective-cohort-study
#14
Joan Margaret O'Donnell, Michael Kerin Morgan, Maurizio Manuguerra
OBJECTIVE Few studies have examined patients' ability to drive and quality of life (QOL) after microsurgical repair for unruptured intracranial aneurysms (uIAs). However, without a strong evidentiary basis, jurisdictional road transport authorities have recommended driving restrictions following brain surgery. In the present study, authors examined the outcomes of the microsurgical repair of uIAs by measuring patients' perceived QOL and cognitive abilities related to driving. METHODS Between January 2011 and January 2016, patients with a new diagnosis of uIA were prospectively enrolled in this study...
March 2, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29489955/characterization-of-aphasia-in-aneurysmal-subarachnoid-hemorrhage
#15
Deborah Karolyne Mendes Maranhão, Moysés Loiola Ponte de Souza, Maria Lúcia Gurgel da Costa, Ana Cláudia de Carvalho Vieira
PURPOSE: Characterize the profile of aphasic syndromes determined by aneurysmal subarachnoid hemorrhage (aSAH) of the left middle cerebral artery (LMCA). METHODS: An analytical, retrospective, cross-sectional study was conducted using a database of cognitive assessments of 193 patients with aSAH admitted to Hospital da Restauração between March 2007 and November 2009. Of these, a total of 26 patients with aSAH in the LMCA territory confirmed by digital angiography were selected...
February 22, 2018: CoDAS
https://www.readbyqxmd.com/read/29434767/simvastatin-inhibits-the-apoptosis-of-hippocampal-cells-in-a-mouse-model-of-alzheimer-s-disease
#16
Xiaoqin Hu, Chengwei Song, Ming Fang, Chengyan Li
Alzheimer's disease is associated with cognitive impairments that affect memory and executive functions. Simvastatin is a cholesterol-lowering statin drug that is used to control levels of cholesterol in the blood, particularly in cases of hypercholesterolemia, and may be used in the treatment of aneurysmal subarachnoid hemorrhage. Previous results have indicated that the apoptosis of hippocampal cells may serve a critical role in the progression of Alzheimer's disease. In the present study, it was determined whether Simvastatin inhibited the apoptosis of hippocampal cells in vitro and in vivo ...
February 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29421452/marriage-and-partnership-integrity-after-aneurysmal-subarachnoid-hemorrhage-small-alterations-in-neurologic-status-matter-most
#17
Daniel Schöni, Lara Lauber, Christian Fung, Johannes Goldberg, René Müri, Andreas Raabe, Thomas Nyffeler, Jürgen Beck
OBJECTIVE: Common sequelae of subarachnoid hemorrhage (SAH) include somatic and/or cognitive impairment. This can cause emotional stress, social tensions, and difficulties in relationships. To test our hypothesis that more severe somatic and cognitive impairments increased the likelihood of disruption of a relationship after SAH, we assessed the integrity of marriage or partnership status in a well-evaluated subset of SAH patients. METHODS: Our sample comprised 50 SAH patients who were discharged to a neurologic, in-house rehabilitation center between 2005 and 2010...
May 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29354334/traumatic-pseudoaneurysm-of-the-distal-anterior-cerebral-artery-following-penetrating-brain-injury-caused-by-a-crossbow-bolt-a-case-report
#18
Daiichiro Ishigami, Takahiro Ota
Traumatic intracranial aneurysms are one possible complication after penetrating brain injury. A 25-year-old man with a history of major depression presented with a crossbow bolt penetrating the head. On arrival, Glasgow Coma Scale score was E4V5M6, with no apparent neurological deficit. Computed tomography (CT) of the head showed the crossbow bolt passing near the corpus callosum, with surrounding contusion. Three-dimensional rotational angiography showed no anterior cerebral artery injuries. The crossbow bolt was removed after bifrontal craniotomy, with no postoperative infection...
January 2018: NMC Case Report Journal
https://www.readbyqxmd.com/read/29322965/endovascular-strategies-for-management-of-intradural-vertebral-artery-dissecting-aneurysms
#19
Swati D Chinchure, Vijay Jaykrishnan, B P Krishna Prasad
OBJECTIVE: Endovascular treatment of vertebral intradural dissecting aneurysms is complex and requires different strategies for each case. The current study aims to classify these aneurysms for an easy selection of optimal strategies for endovascular therapy. MATERIALS AND METHODS: This study is a retrospective evaluation of 10 patients harbouring a vertebral intradural dissecting aneurysm (including 6 female and 4 male patients). The clinical, procedural, and angiographic data were evaluated...
January 2018: Neurology India
https://www.readbyqxmd.com/read/29288107/memory-deficits-after-aneurysmal-subarachnoid-hemorrhage-a-functional-magnetic-resonance-imaging-study
#20
Jiabin Su, Tongzhou E, Qihao Guo, Yu Lei, Yuxiang Gu
BACKGROUND: Patients who have sustained aneurysmal subarachnoid hemorrhage (aSAH) are thought to have cognitive impairment. However, little is known about the characteristics of functional imaging in patients with aSAH. In this study, we explored whole brain activity patterns in patients with aSAH using amplitude of low-frequency fluctuation (ALFF) and functional connectivity (FC). METHODS: Fifty patients with aSAH and 30 healthy controls were recruited and subjected to a resting-state functional magnetic resonance imaging scan and cognitive tasks...
March 2018: World Neurosurgery
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