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https://www.readbyqxmd.com/read/29051516/stromal-striae-a-new-insight-into-corneal-physiology-and-mechanics
#1
Kate Grieve, Djida Ghoubay, Cristina Georgeon, Gael Latour, Amir Nahas, Karsten Plamann, Caroline Crotti, Romain Bocheux, Marie Borderie, Thu-Mai Nguyen, Felipe Andreiuolo, Marie-Claire Schanne-Klein, Vincent Borderie
We uncover the significance of a previously unappreciated structural feature in corneal stroma, important to its biomechanics. Vogt striae are a known clinical indicator of keratoconus, and consist of dark, vertical lines crossing the corneal depth. However we detected stromal striae in most corneas, not only keratoconus. We observed striae with multiple imaging modalities in 82% of 118 human corneas, with pathology-specific differences. Striae generally depart from anchor points at Descemet's membrane in the posterior stroma obliquely in a V-shape, whereas in keratoconus, striae depart vertically from posterior toward anterior stroma...
October 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29034606/do-mid-crown-enamel-formation-front-angles-reflect-factors-linked-to-the-pace-of-primate-growth-and-development
#2
Debbie Guatelli-Steinberg, James D Pampush, Mackie C O'Hara, Song Xing, W Scott McGraw, Rebecca J Ferrell
Enamel formation front (EFF) angles represent the leading edge of enamel matrix secretion at particular points in time. These angles are influenced by rates of enamel extension (the rates at which tooth crowns grow in height), rates of enamel matrix secretion and the angles that prisms make with the enamel-dentine junction. Previous research suggests, but has not yet established, that these angles reflect aspects of primate biology related to their pace of growth and development, most notably brain and body size...
October 16, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28980136/treatment-of-striae-distensae-with-non-ablative-fractional-laser-clinical-and-in-vivo-microscopic-documentation-of-treatment-efficacy
#3
Stefania Guida, M G Galimberti, M Bencini, G Pellacani, P L Bencini
The efficacy of NAFL in the treatment of striae distensae (SD) has been demonstrated. Nevertheless, the base for this improvement has not been clarified yet. The aim of this study is to describe in vivo variations occurring in the skin after the treatment, using reflectance confocal microscopy (RCM). Ten patients asking for the treatment of SD were enrolled. Clinical and RCM images were acquired before the treatment, immediately after 1 and 6 months after the first treatment. One thousand five hundred forty-nanometer laser treatments were performed every 4 weeks for 6 sessions...
October 4, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28979866/cutaneous-manifestations-of-chikungunya-fever-observations-from-an-outbreak-at-a-tertiary-care-hospital-in-southeast-rajasthan-india
#4
Ramesh Kumar, Manoj K Sharma, Suresh K Jain, Sumit K Yadav, Anil K Singhal
BACKGROUND: Chikungunya fever is caused by chikungunya virus which is transmitted by the bite of infected Aedes aegypti and A. albopictus mosquitoes. AIMS: To study the various mucocutaneous manifestations in suspected cases of chikungunya fever. MATERIALS AND METHODS: The patients who attended our outpatient department from July 2016 to October 2016 and fulfilled the criteria for "suspect cases" of chikungunya infection stipulated by the National Institute of Communicable Diseases, Directorate General of Health Services, Government of India, were included in the study prospectively...
September 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/28979657/nonablative-fractional-laser-resurfacing-in-skin-of-color-evidence-based-review
#5
REVIEW
Shivani B Kaushik, Andrew F Alexis
Background: Nonablative laser resurfacing represents one of the major advances in procedural dermatology over the past decade. However, its use in darker skin types is limited by safety concerns and a relative lack of available data. Aim: To provide evidence-based recommendations for the use of fractional lasers in darker skin types. Evidence review: A broad literature search of PubMed/Medline database was conducted in April 2016 using the term fractional lasers. A free text search of keywords including fractional resurfacing, nonablative lasers, skin type, skin of color, ethnic skin, Fitzpatrick skin type, Asian skin, African Americans, Afro-Caribbean, and Hispanics was also executed...
June 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28966524/k%C3%A3-ebner-phenomenon-induced-by-striae-distensae-in-a-vitiligo-patient
#6
Rui-Xing Yu, Yun Hui, Cheng-Rang Li
No abstract text is available yet for this article.
October 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28944123/preventing-cushing-iatrogenic-cushing-syndrome-due-to-ritonavir-fluticasone-interaction
#7
Fasil Tiruneh, Ahmad Awan, Abiot Didana, Saumil Doshi
Ritonavir is commonly used in low doses to boost plasma levels of protease inhibitors in patients with human immunodeficiency virus (HIV) infections. It is also a potent inhibitor of cytochrome P450. We present a 50-year-old African American male with past medical history of HIV on highly active antiretroviral therapy (HAART), which also included ritonavir and long standing asthma that has been treated with inhaled fluticasone, who presented with back pain. He had central obesity, prominent abdominal striae and wasted extremities on physical examination...
July 17, 2017: Curēus
https://www.readbyqxmd.com/read/28900469/necrotic-ulcerated-and-bleeding-striae-distensae-following-bevacizumab-in-a-palliative-setting-for-gliobastomatosis-cerebri
#8
Olivia Laugier, Laetitia Padovani, Arnauld Verschuur, Caroline Gaudy-Marqueste, Nicolas André
Glioblastoma cerebri is a rare paediatric malignancy with dismal prognosis [Chappé C, Riffaud L, and Tréguier C et al (2013) Primary gliomatosis cerebri involving gray matter in pediatrics: a distinct entity? A multicenter study of 14 casesChilds Nerv Syst29 565-571 https://doi.org/10.1007/s00381-012-2016-1 PMID: 23306961] and no established standard of care. Here, we report a case of ulcerated and bleeding striae distensae in a teenage girl following palliative treatment with bevacizumab and steroids.
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/28879667/clinical-biomicroscopy-and-retinoscopy-findings-of-keratoconus-in-a-middle-eastern-population
#9
Mohammad Naderan, Ali Jahanrad, Mahgol Farjadnia
BACKGROUND: The present work was conducted to investigate the prevalence of clinical biomicroscopy and retinoscopy findings of corneas with keratoconus (KC) at first presentation and their relationship with disease severity. METHOD: In a prospective cross-sectional study, 371 consecutive KC patients were examined by slitlamp biomicroscopy and retinoscopy at the time of diagnosis. This research evaluates the prevalence of clinical findings such as a corneal protrusion, Vogt's striae, Fleischer's ring, Munson's sign, Rizzuti's sign, corneal scars, as well as any additional KC signs such as prominent nerve fibres, scissoring reflex and Charleaux 'oil droplet' sign on retinoscopy...
September 6, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28874240/-review-of-online-prescriptions-of-topical-steroids-for-an-obese-boy-with-iatrogenic-cushing-s-syndrome
#10
Sina Dalby, Inge Østergaard
A 14-year-old boy with obesity developed iatrogenic Cushing's syndrome after having received topical steroid therapy for psoriasis. The diagnosis was suspected when he developed striae, moon face and stunted growth. A review of the Danish online registration of prescriptions: Shared Medicine Card, revealed that an amount of 5.1 kg topical steroids had been prescribed during a period of twelve months. Blood tests showed stunted cortisol release. Primary obesity in children is associated with increased growth...
August 28, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28844655/a-missed-diagnosis-of-multiple-intraocular-foreign-bodies-for-21-years
#11
Xubo Yang, Chunling Liu, Longqian Liu, Lanlan Zhang
A 30-year-old patient went to the emergency department because of a chemical burn to the left eye more than 10 days ago by toilet cleanser. Surprisingly, a small piece of glass was found in the inferior anterior chamber in the same eye. The visual acuity was counting fingers. There was conjunctival congestion, corneal oedema and Descemet's membrane striae. And there was also a corneal leukoma around 4 to 5 o'clock. Through repeated questioning he recalled that he was injured by an exploded light bulb around 21 years ago...
August 24, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28819359/screening-for-cushing-syndrome-at-the-primary-care-level-what-every-general-practitioner-must-know
#12
REVIEW
Ernest Yorke, Yacoba Atiase, Josephine Akpalu, Osei Sarfo-Kantanka
Cushing's syndrome is a rare entity, and a high index of suspicion is needed for screening in a primary care setting. The clinical awareness of the primary care physician (PCP) to the highly indicative signs and symptoms such as facial plethora, proximal myopathy, reddish purple striae, and easy bruisability should alert him to look for biochemical evidence of Cushing's syndrome through any of the first-line screening tests, namely, 24-hour urinary free cortisol, overnight dexamethasone suppression test, or late-night salivary cortisol...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28819015/adrenal-cushing-s-syndrome-during-pregnancy
#13
C E Andreescu, R A Alwani, J Hofland, L H J Looijenga, W W de Herder, L J Hofland, R A Feelders
Cushing syndrome (CS) during pregnancy is a rare condition with only a few cases reported in the literature. Misdiagnosis of CS is common because of overlapping features like fatigue, weight gain, striae and emotional changes that can occur during normal pregnancy. Changes in maternal hormones and their binding proteins complicate assessment of glucocorticoid hormone levels during gestation. CS during pregnancy is most frequently due to an adrenal adenoma and to a lesser degree to adrenocorticotropic hormone (ACTH) hypersecretion by a pituitary adenoma...
November 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28818731/association-between-severities-of-striae-gravidarum-and-obstetric-anal-sphincter-injuries-oasis
#14
Ofra Halperin, Anita Noble, Shosh Balachsan, Ester Klug, Michal Liebergall-Wischnitzer
OBJECTIVES: to examine the association between the severities of Striae Gravidarum (SG) and Obstetric Anal Sphincter Injuries (OASIS) and to measure the symptoms regarding urinary incontinence, fecal/flatus incontinence, and dyspareunia, at 6 and 12 months postpartum. DESIGN: this is a cohort study. SETTING: four university teaching medical centers in Israel, two in the north and two in the center of the country. PARTICIPANTS: women with OASIS were interviewed and assessed for SG...
November 2017: Midwifery
https://www.readbyqxmd.com/read/28815554/severe-disruption-and-disorganization-of-dermal-collagen-fibrils-in-early-striae-gravidarum
#15
F Wang, K Calderone, T T Do, N R Smith, Y R Helfrich, T R B Johnson, S Kang, J J Voorhees, G J Fisher
BACKGROUND: Striae gravidarum (SG), or stretch marks of pregnancy, begin as erythematous streaks, and mature into hypopigmented atrophic bands. OBJECTIVES: To investigate molecular alterations that may promote atrophy of SG, we investigated dermal type I collagen fibrils, which provide human skin with support. METHODS: We obtained skin samples of recently developed, erythematous abdominal SG from pregnant women. To examine the organization of collagen fibrils, second-harmonic generation imaging was performed using multiphoton microscopy...
August 17, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28804042/four-hand-suction-irrigation-technique-leads-to-gross-total-resection-and-long-term-progression-free-survival-in-fourth-ventricular-ependymoma
#16
Sascha Marx, Ehab El Refaee, Soenke Langner, Henry W S Schroeder
BACKGROUND: Gross total resection is often avoided in posterior fossa ependymoma surgery due to the fear of permanent neurological deficits after operation. However, the extent of resection is a major prognostic factor for progression free and overall survival. The present study evaluates the outcome of posterior fossa ependymoma gross total resection in adult patients using a four-hand suction-irrigation technique at the floor of the fourth ventricle. METHODS: All surgical procedures for posterior fossa ependymomas performed since 2001 in the Department of Neurosurgery, University Medicine Greifswald, were analysed...
August 10, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28802685/results-at-7years-after-cross-linking-procedure-in-keratoconic-patients
#17
C Nicula, D Nicula, R N Pop
PURPOSE: Long-term evaluation of functional results based on visual acuity, keratometry, spherical equivalent and refractive cylinder in patients with progressive keratoconus treated with corneal collagen cross-linking (CXL). MATERIALS AND METHODS: We studied a group of 114 eyes of 91 consecutive patients treated from 2006 to 2009 by "Epi-off type" CXL. In the preoperative period, all patients had a complete ophthalmologic examination. The inclusion criteria were: patients aged 15 to 54years, with various stages of keratoconus, with a corneal thickness of at least 400μm at the thinnest point...
September 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28796657/microneedling-a-review-and-practical-guide
#18
Tina S Alster, Paul M Graham
BACKGROUND: Microneedling is a relatively new treatment option in dermatology and has been touted for a broad range of applications including skin rejuvenation, acne scarring, rhytides, surgical scars, dyschromia, melasma, enlarged pores, and transdermal drug delivery. The significant increase in minimally invasive procedures that has been reported over the past several years suggest that microneedling may occupy a specific niche for patients who desire measurable clinical results from treatments with little to no recovery...
August 7, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28792112/a-pilot-study-of-treatment-of-striae-distensae-with-variable-square-pulse-erbium-yag-laser-resurfacing
#19
Rungsima Wanitphakdeedecha, Walailak Meeprathom, Woraphong Manuskiatti
BACKGROUND: Striae distensae (SD) are a frequent skin condition for which treatment remains a challenge. Various laser treatments have been employed to remove the epidermis and cause dermal wound and heating with subsequent dermal collagen remodeling. OBJECTIVE: To determine the efficacy and safety of a variable square pulse Erbium: YAG (VSP Er:YAG) laser for the treatment of striae in skin phototypes III-IV. METHODS: Twenty-one women with SD were treated monthly for 2 months with VSP Er:YAG laser resurfacing using a 7-mm spot size...
August 9, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28762352/a-comparative-study-to-associate-the-presence-of-neonatal-line-in-deciduous-teeth-of-infants-with-the-occurrence-of-live-birth
#20
Shruti Srinivasan, Prashanth Sadashiva Murthy, Seema Deshmukh, N M Shamsundar
CONTEXT: The prominent striae of retzius corresponding to the occurrence of live birth is known as the neonatal line (NNL). The very presence of this line indicates the exposure of the infant to the stressful event of birth. AIMS: The study was aimed at locating the NNL in the developing primary teeth of the neonate and associating the presence of NNL to the occurrence of live birth. MATERIALS AND METHODS: The donated bodies of the neonates were taken, and a surgical incision was made along the crest of the alveolar ridge in the maxillary anterior region, enabling the careful removal of the tooth germs from within the jaw segment...
July 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
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