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https://www.readbyqxmd.com/read/28819359/screening-for-cushing-syndrome-at-the-primary-care-level-what-every-general-practitioner-must-know
#1
REVIEW
Ernest Yorke, Yacoba Atiase, Josephine Akpalu, Osei Sarfo-Kantanka
Cushing's syndrome is a rare entity, and a high index of suspicion is needed for screening in a primary care setting. The clinical awareness of the primary care physician (PCP) to the highly indicative signs and symptoms such as facial plethora, proximal myopathy, reddish purple striae, and easy bruisability should alert him to look for biochemical evidence of Cushing's syndrome through any of the first-line screening tests, namely, 24-hour urinary free cortisol, overnight dexamethasone suppression test, or late-night salivary cortisol...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28819015/adrenal-cushing-s-syndrome-during-pregnancy
#2
Corina Andreescu, Rehmat Ali Alwani, Johannes Hofland, Leendert Looijenga, Wouter de Herder, Leo Hofland, Richard A Feelders
Cushing syndrome (CS) during pregnancy is a rare condition with only a few cases reported in the literature. Misdiagnosis of CS is common because of overlapping features like fatigue, weight gain, striae and emotional changes that can occur during normal pregnancy. Changes in maternal hormones and their binding proteins complicate assessment of glucocorticoid hormone levels during gestation. CS during pregnancy is most frequently due to an adrenal adenoma and to a lesser degree to adrenocorticotropic hormone (ACTH) hypersecretion by a pituitary adenoma...
August 17, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28818731/association-between-severities-of-striae-gravidarum-and-obstetric-anal-sphincter-injuries-oasis
#3
Ofra Halperin, Anita Noble, Shosh Balachsan, Ester Klug, Michal Liebergall-Wischnitzer
OBJECTIVES: to examine the association between the severities of Striae Gravidarum (SG) and Obstetric Anal Sphincter Injuries (OASIS) and to measure the symptoms regarding urinary incontinence, fecal/flatus incontinence, and dyspareunia, at 6 and 12 months postpartum. DESIGN: this is a cohort study. SETTING: four university teaching medical centers in Israel, two in the north and two in the center of the country. PARTICIPANTS: women with OASIS were interviewed and assessed for SG...
August 1, 2017: Midwifery
https://www.readbyqxmd.com/read/28815554/severe-disruption-and-disorganization-of-dermal-collagen-fibrils-in-early-striae-gravidarum
#4
F Wang, K Calderone, T T Do, N R Smith, Y R Helfrich, T R B Johnson, S Kang, J J Voorhees, G J Fisher
BACKGROUND: Striae gravidarum (SG), or stretch marks of pregnancy, begin as erythematous streaks, and mature into hypopigmented atrophic bands. OBJECTIVES: To investigate molecular alterations that may promote atrophy of SG, we investigated dermal type I collagen fibrils, which provide human skin with support. METHODS: We obtained skin samples of recently developed, erythematous abdominal SG from pregnant women. To examine the organization of collagen fibrils, second-harmonic generation imaging was performed using multiphoton microscopy...
August 17, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28802685/results-at-7years-after-cross-linking-procedure-in-keratoconic-patients
#5
C Nicula, N Dorin, P R Nicolae
PURPOSE: Long-term evaluation of functional results based on visual acuity, keratometry, spherical equivalent and refractive cylinder in patients with progressive keratoconus treated with corneal collagen cross-linking (CXL). MATERIALS AND METHODS: We studied a group of 114 eyes of 91 consecutive patients treated from 2006 to 2009 by "Epi-off type" CXL. In the preoperative period, all patients had a complete ophthalmologic examination. The inclusion criteria were: patients aged 15 to 54years, with various stages of keratoconus, with a corneal thickness of at least 400μm at the thinnest point...
August 9, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28796657/microneedling-a-review-and-practical-guide
#6
Tina S Alster, Paul M Graham
BACKGROUND: Microneedling is a relatively new treatment option in dermatology and has been touted for a broad range of applications including skin rejuvenation, acne scarring, rhytides, surgical scars, dyschromia, melasma, enlarged pores, and transdermal drug delivery. The significant increase in minimally invasive procedures that has been reported over the past several years suggest that microneedling may occupy a specific niche for patients who desire measurable clinical results from treatments with little to no recovery...
August 7, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28792112/a-pilot-study-of-treatment-of-striae-distensae-with-variable-square-pulse-erbium-yag-laser-resurfacing
#7
Rungsima Wanitphakdeedecha, Walailak Meeprathom, Woraphong Manuskiatti
BACKGROUND: Striae distensae (SD) are a frequent skin condition for which treatment remains a challenge. Various laser treatments have been employed to remove the epidermis and cause dermal wound and heating with subsequent dermal collagen remodeling. OBJECTIVE: To determine the efficacy and safety of a variable square pulse Erbium: YAG (VSP Er:YAG) laser for the treatment of striae in skin phototypes III-IV. METHODS: Twenty-one women with SD were treated monthly for 2 months with VSP Er:YAG laser resurfacing using a 7-mm spot size...
August 9, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28762352/a-comparative-study-to-associate-the-presence-of-neonatal-line-in-deciduous-teeth-of-infants-with-the-occurrence-of-live-birth
#8
Shruti Srinivasan, Prashanth Sadashiva Murthy, Seema Deshmukh, N M Shamsundar
CONTEXT: The prominent striae of retzius corresponding to the occurrence of live birth is known as the neonatal line (NNL). The very presence of this line indicates the exposure of the infant to the stressful event of birth. AIMS: The study was aimed at locating the NNL in the developing primary teeth of the neonate and associating the presence of NNL to the occurrence of live birth. MATERIALS AND METHODS: The donated bodies of the neonates were taken, and a surgical incision was made along the crest of the alveolar ridge in the maxillary anterior region, enabling the careful removal of the tooth germs from within the jaw segment...
July 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28755402/combination-of-a-2940%C3%A2-nm-er-yag-laser-with-recombinant-bovine-basic-fibroblast-growth-factor-rb-bfgf-and-light-emitting-diode-red-light-led-rl-for-the-treatment-of-striae-alba-a-pilot-study
#9
Jie Shen, Xin-Gang Lu, Jing-Jing Jin, Hong-Wei Wang
BACKGROUND: Striae distensae (SD) are a common dermatologic problem that plagues many people. Although there are many therapeutic modalities have been used to treat SD, effective method has been disappointing for striae Alba. AIMS: To evaluate the clinical and histopathologic efficacy and safety of the 2940-nm erbium yttrium aluminum garnet (Er:YAG) ablative fractional laser (AFL) with recombinant bovine basic fibroblast growth factor (rb-bFGF) and light-emitting diode-red light (LED-RL) for the treatment of striae alba...
July 29, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28742840/glaucomatous-changes-in-lamina-pores-shape-within-the-lamina-cribrosa-using-wide-bandwidth-femtosecond-mode-locked-laser-oct
#10
Takuhei Shoji, Hiroto Kuroda, Masayuki Suzuki, Hisashi Ibuki, Makoto Araie, Shin Yoneya
PURPOSE: The lamina cribrosa (LC) is known to play a critical role in the pathogenesis of glaucoma. Although it has been reported that striae-shaped or slit-shaped lamina pores are more frequent in eyes with primary open angle glaucoma (POAG), this observation is based only on fundus photography. The primary object of this study is to perform layer-by-layer comparisons of the shape of lamina pores within the LC in vivo. DESIGN: Cross-sectional study. METHODS: Optic nerve head B-scans were obtained using custom-made broad-wavelength optical coherence tomography with a mode-locked laser...
2017: PloS One
https://www.readbyqxmd.com/read/28716850/fluid-filled-striae-in-a-patient-with-hypoalbuminemia
#11
Maria Jogova, Stephen W Hwang
No abstract text is available yet for this article.
July 17, 2017: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/28706489/difference-in-striae-periodicity-of-heilongjiang-and-singaporean-chinese-teeth
#12
Sharon H X Tan, Yu Fan Sim, Chin-Ying S Hsu
Striae periodicity refers to the number of cross-striations between successive lines of Retzius in tooth enamel. A regular time dependency of striae periodicity, known as the circaseptan interval, has been proposed. Previous studies on striae periodicity have been carried out on both modern and early humans given its potential applications in forensic age estimations and anthropology. Nevertheless, research comparing striae periodicities across gender groups and populations in different geographical locations, particularly in Asia, is lacking...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28690124/microneedling-where-do-we-stand-now-a-systematic-review-of-the-literature
#13
REVIEW
Lisa Ramaut, Henk Hoeksema, Ali Pirayesh, Filip Stillaert, Stan Monstrey
BACKGROUND: Patients who suffer from scars or wrinkles have several therapeutic options to improve the appearance of their skin. The available treatment modalities that provide desirable results are often overtly invasive and entail a risk of undesirable adverse effects. Microneedling has recently emerged as a non-ablative alternative for treating patients who are concerned with the aesthetic changes that result from injury, disease or ageing. OBJECTIVE: This review aims to evaluate the current evidence in the literature on microneedling...
June 17, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28665161/long-term-results-of-the-treatment-of-pregnancy-induced-striae-distensae-using-a-1550-nm-non-ablative-fractional-laser
#14
Hilal Gokalp
BACKGROUND: Striae distensae (SD) are a type of dermal scarring that is quite common and difficult to treat. Two forms are known: striae rubrae (SR) and striae albae (SA). OBJECTIVE: We evaluated and compared the long-term clinical effectiveness of SR and SA treatment using a 1550-nm non-ablative fractional laser (NAFL). MATERIALS AND METHODS: We included 16 female patients (8 with SR and 8 with SA) who had developed abdominal SD during pregnancy...
June 30, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28665146/pressure-and-dose-controlled-transcutaneous-pneumatic-injection-of-hypertonic-glucose-solution-for-the-treatment-of-atrophic-skin-disorders
#15
Heesu Kim, Kwang Ho Yoo, Zhenlong Zheng, Sung Bin Cho
Background Needleless transcutaneous pneumatic injections (TPI) are a minimally invasive way to deliver solution into the skin for therapeutic purposes. The suggested action mechanisms of TPI therapy include mechanical stimulation, immediate tissue shrinkage, and late wound healing. Methods Thirteen Korean patients were treated with TPI for atrophic skin disorders, including acne scars, striae albae, post-furuncle or carbuncle scars, and horizontal wrinkles with lipoatrophy. At each TPI treatment session, a single pass was made along on the atrophic skin lesions without overlapping...
June 30, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28658887/a-screening-study-on-dermatoses-in-pregnancy
#16
K Kannambal, G K Tharini
INTRODUCTION: Pregnancy produces many cutaneous changes, some of which are specifically related to pregnancy (dermatoses of pregnancy), some are modifiable by pregnancy and others that are common are named physiologic. These physiologic skin changes, usually do not impair the health of the mother or the fetus but some of them can be cosmetically significant and of importance to the dermatologist. AIM: The present study was undertaken to find out the prevalence of the physiological and pathological skin changes in pregnancy, and to correlate the prevalence of the major cutaneous changes and diseases in relation to different trimesters of pregnancy and with gravidity...
May 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28648713/zoonotic-infection-with-onchocerca-dewittei-japonica-in-an-11-year-old-boy-in-kansai-region-western-honshu-japan
#17
Shigehiko Uni, Masako Fukuda, Kou Ogawa, Yvonne Ai-Lian Lim, Takeshi Agatsuma, Naruemon Bunchom, Weerachai Saijuntha, Yasushi Otsuka, Subha Bhassu, Ahmad Syihan Mat Udin, Nur Afiqah Zainuri, Hasmahzaiti Omar, Jun Nakatani, Makoto Matsubayashi, Haruhiko Maruyama, Rosli Ramli, Mohd Sofian Azirun, Hiroyuki Takaoka
An 11-year-old boy living in Otsu City, Shiga Prefecture, Kansai Region, Western Honshu, Japan had zoonotic onchocercosis. The patient developed a painful swelling on the little finger of his left hand. The worm detected in the excised mass had external transverse ridges but did not have inner striae in the cuticle. On the basis of the parasite's histopathological characteristics, the causative agent was identified as a female Onchocerca dewittei japonica (Spirurida: Onchocercidae). The species of the filarial parasite was confirmed by sequencing the cox1 gene of the parasite...
June 23, 2017: Parasitology International
https://www.readbyqxmd.com/read/28643710/postoperative-posterior-capsular-striae-and-the-posterior-capsular-opacification-in-patients-implanted-with-two-types-of-intraocular-lens-material
#18
Rajesh Subhash Joshi
AIM: To evaluate the incidence of postoperative posterior capsular striae (PCS) and its influence on posterior capsular opacification (PCO) in patients implanted with two types of lens material. SETTING: Tertiary eye care center in central rural India. STUDY DESIGN: A prospective, observational, nonrandomized study. MATERIALS AND METHODS: The study included 1247 patients having age-related cataract scheduled for removal by phacoemulsification technique and implantation of hydrophilic or hydrophobic intraocular lens (IOL)...
June 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28639683/traitement-m%C3%A3-dicamenteux-du-lichen-plan-buccal
#19
Jan S Schenkel, Heinz-Theo Lübbers, Claudio Rostetter, Philipp Metzler
Oral lichen planus is a relatively common T-cell mediated inflammatory disease with potential malignant transformation. It may present itself with pain and oral lesions such as ulcers and Wickham’s striae. Treatment includes topical corticosteroids, preferably Clobetasol, immunosuppressive drugs and retinoids. Hyaluronic acid and aloe vera have been proven to be successful. If topical treatment fails, systemic therapy with corticosteroids may be needed. Because of the potential malignant transformation periodic follow-up is mandatory...
2017: Swiss Dental Journal
https://www.readbyqxmd.com/read/28639555/ginkgo-biloba-and-lycopene-are-effective-on-cisplatin-induced-ototoxicity
#20
Erkan Esen, Fatih Özdoğan, Seren Gülşen Gürgen, Halil Erdem Özel, Serdar Başer, Selahattin Genç, Adin Selçuk
OBJECTIVE: The purpose of this study was to examine the anti-ototoxic impact of Ginkgo biloba extract and lycopene on the model of cisplatin-induced ototoxicity in rats. MATERIALS AND METHODS: Thirty-two Wistar albino rats were examined with the distortion product otoacoustic emission (DPOAE) test (MADSEN Capella2 ; GN Otometrics, ICS Medical, Chicago USA), and they were randomly divided into four groups. Group 1 (n=8) was defined as the healthy control group. Cisplatin was given intraperitoneally as single dose of 12 mg/kg to group 2 (n=8), group 3 (n=8), and group 4 (n=8)...
June 21, 2017: Journal of International Advanced Otology
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