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https://www.readbyqxmd.com/read/29347726/deceleration-of-one-dimensional-mixing-by-discontinuous-mappings
#1
Hannah Kreczak, Rob Sturman, Mark C T Wilson
We present a computational study of a simple one-dimensional map with dynamics composed of stretching, permutations of equally sized cells, and diffusion. We observe that the combination of the aforementioned dynamics results in eigenmodes with long-time exponential decay rates. The decay rate of the eigenmodes is shown to be dependent on the choice of permutation and changes nonmonotonically with the diffusion coefficient for many of the permutations. The global mixing rate of the map M in the limit of vanishing diffusivity approximates well the decay rates of the eigenmodes for small diffusivity, however this global mixing rate does not bound the rates for all values of the diffusion coefficient...
November 2017: Physical Review. E
https://www.readbyqxmd.com/read/29329275/chitosan-starch-films-with-natural-extracts-physical-chemical-morphological-and-thermal-properties
#2
Jessica I Lozano-Navarro, Nancy P Díaz-Zavala, Carlos Velasco-Santos, José A Melo-Banda, Ulises Páramo-García, Francisco Paraguay-Delgado, Ricardo García-Alamilla, Ana L Martínez-Hernández, Samuel Zapién-Castillo
The aim of this study is to analyze the properties of a series of polysaccharide composite films, such as apparent density, color, the presence of functional groups, morphology, and thermal stability, as well as the correlation between them and their antimicrobial and optical properties. Natural antioxidants such as anthocyanins (from cranberry; blueberry and pomegranate); betalains (from beetroot and pitaya); resveratrol (from grape); and thymol and carvacrol (from oregano) were added to the films. Few changes in the position and intensity of the FTIR spectra bands were observed despite the low content of extract added to the films...
January 12, 2018: Materials
https://www.readbyqxmd.com/read/29326087/a-multicomponent-exercise-program-improves-physical-function-in-long-term-nursing-home-residents-a-randomized-controlled-trial
#3
Haritz Arrieta, Chloe Rezola, Idoia Zarrazquin, Iñaki Echeverria, Jose Javier Yanguas, Miren Iturburu, Susana Maria Gil, Ana Rodriguez-Larrad, Jon Irazusta
To investigate the impact of a multicomponent exercise program on anthropometry, physical function, and physical activity on older adults living in long-term nursing homes (LTNH), we conducted a randomized controlled trial involving 112 participants aged 84.9 ± 6.9 years. Participants were randomly assigned to an intervention (IG) or control group (CG). The IG participated in a 3-month multicomponent exercise intervention focused on strength, balance, stretching exercises, and walking recommendations...
January 8, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29316152/clinical-and-immunohistochemical-comparative-study-of-the-efficacy-of-carboxytherapy-vs-platelet-rich-plasma-in-treatment-of-stretch-marks
#4
Abeer A Hodeib, Ghada F R Hassan, Marwa N M Ragab, Eiman A Hasby
BACKGROUND: Striae distensae are dermal scars with a linear atrophic depression. The exact origin of striae distensae remains unrevealed, but low expression of collagen and fibronectin genes in the affected tissue was found. Several treatment modalities have been proposed, yet no consistent modality is available. AIM OF THE WORK: To evaluate and compare the efficacy and safety of carboxytherapy vs platelet-rich plasma (PRP) in treatment of stretch marks. PATIENTS AND METHODS: This study included 20 patients with striae alba...
January 7, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29313060/an-md2-derived-peptide-promotes-lps-aggregation-facilitates-its-internalization-in-thp-1-cells-and-inhibits-lps-induced-pro-inflammatory-responses
#5
Anshika Tandon, Munesh Kumar Harioudh, Nayab Ishrat, Amit Kumar Tripathi, Saurabh Srivastava, Jimut Kanti Ghosh
MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS). Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host. However, not much is known about the segments in MD2 that are responsible for LPS interaction or internalization of pathogen inside the defense cells. A 16-residue stretch (MD54) from MD2 protein has been identified that possesses a short heptad repeat sequence and four cationic residues enabling it to participate in both hydrophobic and electrostatic interactions with LPS...
January 8, 2018: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/29272925/communication-spectroscopic-characterization-of-a-strongly-interacting-c-2-h-group-on-the-emim-cation-in-the-emim-2x-x-bf4-cl-br-and-i-ternary-building-blocks-of-ionic-liquids
#6
Olga Gorlova, Stephanie M Craig, Mark A Johnson
To unravel the intermolecular interactions at play in the assemblies of EMIM-based ionic liquids, we report the vibrational spectra of the cryogenically cooled, cationic ternary complexes with halide ions, (EMIM+)2X-, X = Cl, Br, and I. This series specifically addresses the spectral response of the acidic C(2)H group upon complexation with an atomic anion, which is isolated by selective deuteration at this position. Unlike the behavior of the related BF4- complex, the halide systems display large (∼175 cm-1) red-shifts and dramatic (∼30X) intensity enhancements in the C(2)D stretch (relative to that of the bare d(2)-EMIM+ cation), which are largest for the chloride anion...
December 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29258505/malaria-prevalence-in-mangaluru-city-area-in-the-southwestern-coastal-region-of-india
#7
Kiran K Dayanand, Kishore Punnath, Valleesha Chandrashekar, Rajeshwara N Achur, Srinivas B Kakkilaya, Susanta K Ghosh, Suchetha Kumari, D Channe Gowda
BACKGROUND: Malaria is highly prevalent in many parts of India and the Indian subcontinent. Mangaluru, a city in the southwest coastal region of Karnataka state in India, and surrounding areas are malaria endemic with 10-12 annual parasite index. Despite high endemicity, to-date, very little has been reported on the epidemiology and burden of malaria in this area. METHODS: A cross-sectional surveillance of malaria cases was performed among 900 febrile symptomatic native people (long-time residents) and immigrant labourers (temporary residents) living in Mangaluru city area...
December 19, 2017: Malaria Journal
https://www.readbyqxmd.com/read/29248638/peptide-and-peptide-carbon-nanotube-hydrogels-as-scaffolds-for-tissue-3d-tumor-engineering
#8
Mohammadali Sheikholeslam, Scott D Wheeler, Keely G Duke, Mungo Marsden, Mark Pritzker, P Chen
The use of hybrid self-assembling peptide (EFK8)-carbon nanotube (SWNT) hydrogels for tissue engineering and in vitro 3D cancer spheroid formation is reported. These hybrid hydrogels are shown to enhance the attachment, spreading, proliferation and movement of NIH-3T3 cells relative to that observed using EFK8-only hydrogels. After five days, ∼30% more cells are counted when the hydrogel contains SWNTs. Also, 3D encapsulation of these cells when injected in hydrogels does not adversely affect their behavior...
December 14, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29238214/pain-sensitivity-and-torque-used-during-measurement-predicts-change-in-range-of-motion-at-the-knee
#9
Mark D Bishop, Steven Z George
Objective: To determine the extent to which changes in knee range of motion (ROM) after a stretching program are related to sensory factors at the time of testing and the amount of force used during the measurement of ROM, rather than changes in soft-tissue properties. Design: Randomized, single-blind design. Participants were randomly assigned to a control or stretching group. Setting: Research laboratory. Participants: Forty-four healthy volunteers (22...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/29232713/long-disordered-regions-of-the-c-terminal-domain-of-abelson-tyrosine-kinase-have-specific-and-additive-functions-in-regulation-and-axon-localization
#10
Han S J Cheong, Mark F A VanBerkum
Abelson tyrosine kinase (Abl) is a key regulator of actin-related morphogenetic processes including axon guidance, where it functions downstream of several guidance receptors. While the long C-terminal domain (CTD) of Abl is required for function, its role is poorly understood. Here, a battery of mutants of Drosophila Abl was created that systematically deleted large segments of the CTD from Abl or added them back to the N-terminus alone. The functionality of these Abl transgenes was assessed through rescue of axon guidance defects and adult lethality in Abl loss-of-function, as well as through gain-of-function effects in sensitized slit or frazzled backgrounds that perturb midline guidance in the Drosophila embryonic nerve cord...
2017: PloS One
https://www.readbyqxmd.com/read/29230371/mass-marking-of-juvenile-schizothorax-wangchiachii-fang-with-alizarin-red-s-and-evaluation-of-stock-enhancement-in-the-jinping-area-of-the-yalong-river
#11
Kun Yang, Shu Li, Xiaoshuai Liu, Weixiong Gan, Longjun Deng, Yezhong Tang, Zhaobin Song
Schizothorax wangchiachii is a key fish species in the stock enhancement program of the Yalong River hydropower project, China. Alizarin red S (ARS) was used to mark large numbers of juvenile S. wangchiachii in the Jinping Hatchery and later used to evaluate stock enhancement in the Jinping area of the Yalong River. In a small-scale pilot study, 7,000 juveniles of the 2014 cohort were successfully marked by immersion in ARS solution, and no mortality was recorded during the marking process. The ARS mark in the fish otoliths remained visible 20 months later...
2017: PeerJ
https://www.readbyqxmd.com/read/29230070/assessing-climate-change-impacts-on-the-stability-of-small-tidal-inlets-part-2-data-rich-environments
#12
Trang Minh Duong, Roshanka Ranasinghe, Marcus Thatcher, Sarith Mahanama, Zheng Bing Wang, Pushpa Kumara Dissanayake, Mark Hemer, Arjen Luijendijk, Janaka Bamunawala, Dano Roelvink, Dirkjan Walstra
Climate change (CC) is likely to affect the thousands of bar-built or barrier estuaries (here referred to as Small tidal inlets - STIs) around the world. Any such CC impacts on the stability of STIs, which governs the dynamics of STIs as well as that of the inlet-adjacent coastline, can result in significant socio-economic consequences due to the heavy human utilisation of these systems and their surrounds. This article demonstrates the application of a process based snap-shot modelling approach, using the coastal morphodynamic model Delft3D, to 3 case study sites representing the 3 main STI types; Permanently open, locationally stable inlets (Type 1), Permanently open, alongshore migrating inlets (Type 2) and Seasonally/Intermittently open, locationally stable inlets (Type 3)...
January 1, 2018: Marine Geology
https://www.readbyqxmd.com/read/29223103/bilateral-early-activity-in-the-hip-flexors-associated-with-falls-in-stroke-survivors-preliminary-evidence-from-laboratory-induced-falls
#13
Dmitrijs Celinskis, Mark D Grabiner, Claire F Honeycutt
OBJECTIVE: Falls are the most common and expensive medical complication following stroke. Hypermetric reflexes have been suggested to impact post-stroke balance but no study has evaluated reflex amplitudes under real conditions of falls in this population. Our objective was to quantify the early reflexive responses during falls induced in the laboratory. METHODS: Sixteen stroke survivors were exposed to posteriorly directed treadmill perturbations that required a forward step to maintain a balance...
November 21, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29214715/cutometric-assessment-of-elasticity-of-skin-with-striae-distensae-following-carboxytherapy
#14
Kasjana Podgórna, Anna Kołodziejczak, Helena Rotsztejn
OBJECTIVE: The aim of the study was to evaluate the effectiveness of carboxytherapy in the treatment of striae distensae. Additionally, discomfort and side effects associated with the treatment were assessed. MATERIALS AND METHODS: This study involved 15 women aged 22-40 years. They underwent 3 sessions of carboxytherapy at one-week intervals. Treatment was performed in skin area within stretch marks located on stomach, buttocks, and thighs. Cutometric probe was used to evaluate skin elasticity...
December 6, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29199132/brainphys%C3%A2-increases-neurofilament-levels-in-cns-cultures-and-facilitates-investigation-of-axonal-damage-after-a-mechanical-stretch-injury-in-vitro
#15
Travis C Jackson, Shawn E Kotermanski, Edwin K Jackson, Patrick M Kochanek
Neurobasal®/B27 is a gold standard culture media used to study primary neurons in vitro. An alternative media (BrainPhys®/SM1) was recently developed which robustly enhances neuronal activity vs. Neurobasal® or DMEM. To the best of our knowledge BrainPhys® has not been explored in the setting of neuronal injury. Here we characterized the utility of BrainPhys® in a model of in vitro mechanical-stretch injury. METHODS/RESULTS: Primary rat cortical neurons were maintained in classic Neurobasal®, or sequentially maintained in Neurocult® followed by BrainPhys® (hereafter simply referred to as "BrainPhys® maintained neurons")...
November 30, 2017: Experimental Neurology
https://www.readbyqxmd.com/read/29159996/demographic-characteristics-of-teenage-boys-with-horizontal-striae-distensae-of-the-lower-back
#16
Emily Boozalis, Anna L Grossberg, Katherine B Puttgen, Candrice R Heath, Bernard A Cohen
BACKGROUND: This study examines the clinical characteristics and demographics of teenage boys with horizontal striae distensae of the lower back in an outpatient setting. METHODS: Retrospective medical chart reviews and telephone survey studies were completed on an outpatient cohort of 12 boys 11 to 17 years of age with a clinical diagnosis of transverse striae distensae of the lower back at a single-center, university-based, pediatric dermatology practice. We evaluated the clinical features of the striae, participant demographic characteristics, and past medical history...
November 21, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/29142095/patterns-of-intermuscular-inhibitory-force-feedback-across-cat-hindlimbs-suggest-a-flexible-system-for-regulating-whole-limb-mechanics
#17
Mark A Lyle, T Richard Nichols
Prior work has suggested that Golgi tendon organ feedback, via its distributed network linking muscles spanning all joints, could be used by the nervous system to help regulate whole limb mechanics if appropriately organized. We tested this hypothesis by characterizing the patterns of intermuscular force dependent feedback between the primary extensor muscles spanning the knee, ankle and toes in decerebrate cat hindlimbs. Intermuscular force feedback was evaluated by stretching tendons of selected muscles in isolation and in pairwise combinations and then measuring the resulting force dependent intermuscular interactions...
November 15, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29131295/the-intracardiac-concentrations-of-the-n-terminal-pro-b-type-natriuretic-peptide-nt-probnp-and-the-determinants-of-its-secretion-in-patients-with-atrial-fibrillation
#18
Witold Streb, Katarzyna Mitręga, Magdalena Szymała, Aleksandra Woźniak, Tomasz Podolecki, Zbigniew Kalarus
BACKGROUND: N-terminal-pro Brain Natriuretic Peptide (NT-proBNP) is elevated not only in heart failure (HF) but also in atrial fibrillation (AF). The role and secretion pattern of NT-proBNP in AF is still undetermined. AIM: The study aimed to assess NT-proBNP concentrations in patients with and without preserved left ventricular ejection fraction (LV-EF) depending on the type of AF. It was also intended to define the main source of NT-proBNP production within the heart...
November 13, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/29120006/manufactured-brace-modalities-for-elbow-stiffness
#19
Nipun Sodhi, Anton Khlopas, Michael D Vaughn, Jaiben George, George Yakubek, Assem A Sultan, Steven F Harwin, Michael A Mont
Multiple surgical and nonsurgical treatment options exist for patients with elbow stiffness. Many nonsurgical mobilization bracing options have been implemented to increase elbow range of motion. Three of the main bracing options for these patients are turnbuckle, static progressive stretch, and dynamic bracing. The purpose of this study was to review the current literature on turnbuckle, static progressive stretch, and dynamic bracing to provide information for practitioners and patients regarding which brace is more appropriate to use for elbow stiffness...
November 8, 2017: Orthopedics
https://www.readbyqxmd.com/read/29116102/epigenetic-transitions-and-knotted-solitons-in-stretched-chromatin
#20
D Michieletto, E Orlandini, D Marenduzzo
The spreading and regulation of epigenetic marks on chromosomes is crucial to establish and maintain cellular identity. Nonetheless, the dynamic mechanism leading to the establishment and maintenance of tissue-specific, epigenetic pattern is still poorly understood. In this work we propose, and investigate in silico, a possible experimental strategy to illuminate the interplay between 3D chromatin structure and epigenetic dynamics. We consider a set-up where a reconstituted chromatin fibre is stretched at its two ends (e...
November 7, 2017: Scientific Reports
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