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https://www.readbyqxmd.com/read/28734256/3d-porous-polyurethanes-featured-by-different-mechanical-properties-characterization-and-interaction-with-skeletal-muscle-cells
#1
Lorenzo Vannozzi, Leonardo Ricotti, Tommaso Santaniello, Tercio Terencio, Reinier Oropesa-Nunez, Claudio Canale, Francesca Borghi, Arianna Menciassi, Cristina Lenardi, Irini Gerges
The fabrication of biomaterials for interaction with muscle cells has attracted significant interest in the last decades. However, 3D porous scaffolds featured by a relatively low stiffness (almost matching the natural muscle one) and highly stable in response to cyclic loadings are not available at present, in this context. This work describes 3D polyurethane-based porous scaffolds featured by different mechanical properties. Biomaterial stiffness was finely tuned by varying the cross-linking degree of the starting foam...
July 14, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28733091/histological-analysis-of-the-association-of-low-level-laser-therapy-and-platelet-rich-plasma-in-regeneration-of-muscle-injury-in-rats
#2
Thiago Alves Garcia, Regina Celi Trindade Camargo, Tatiana Emy Koike, Guilherme Akio Tamura Ozaki, Robson Chacon Castoldi, José Carlos Silva Camargo Filho
OBJECTIVE: Muscle injuries are common, and their treatment requires costs and time off. Platelet rich plasma and low level laser therapy have been shown to be affordable and easy to use. The aim of this study was to evaluate the associated effects of low level laser therapy and platelet rich plasma on the treatment of the soleus muscle injured by strain in rats. METHODS: Thirty-five rats were randomly allocated into five groups: Control (C), Injury Control (IC), injury PRP (IP), injury LLLT (ILT) and injury LLLT and PRP (ILTP)...
July 4, 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28731378/experimental-infection-of-cattle-with-a-novel-prion-derived-from-atypical-h-type-bovine-spongiform-encephalopathy
#3
Hiroyuki Okada, Kentaro Masujin, Kohtaro Miyazawa, Yoshihumi Iwamaru, Morikazu Imamura, Yuichi Matsuura, Shozo Arai, Shigeo Fukuda, Yuichi Murayama, Takashi Yokoyama
H-type bovine spongiform encephalopathy (H-BSE) is an atypical form of BSE in cattle. During passaging of H-BSE in transgenic bovinized (TgBoPrP) mice, a novel phenotype of BSE, termed BSE-SW emerged and was characterized by a short incubation time and host weight loss. To investigate the biological and biochemical properties of the BSE-SW prion, a transmission study was conducted in cattle, which were inoculated intracerebrally with brain homogenate from BSE-SW-infected TgBoPrP mice. The disease incubation period was approximately 15 months...
January 1, 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28730804/wearable-and-transparent-capacitive-strain-sensor-with-high-sensitivity-based-on-patterned-ag-nanowire-networks
#4
Seung-Rok Kim, Jin-Hoon Kim, Jin-Woo Park
In this study, a transparent and stretchable thin-film capacitive strain sensor based on patterned Ag nanowire networks (AgNWs) was successfully fabricated. The AgNWs were patterned using a capillary force lithography (CFL) method and were embedded onto the surface of the polydimethylsiloxane (PDMS) substrate. The strain (ε) sensitivity of the capacitive strain sensor was controlled and enhanced by patterning the AgNWs into electrodes with an interdigitated shape. Interdigitated capacitive strain sensor (ICSS) is expected to have -1...
July 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28729213/physical-exercise-increases-sestrin-2-protein-levels-and-induces-autophagy-in-the-skeletal-muscle-of-old-mice
#5
Luciene Lenhare, Barbara M Crisol, Vagner R R Silva, Carlos K Katashima, André V Cordeiro, Karina D Pereira, Augusto D Luchessi, Adelino S R da Silva, Dennys E Cintra, Leandro P Moura, José R Pauli, Eduardo R Ropelle
Sestrins and autophagy deficiencies are associated with several aging-related organic dysfunctions and metabolic disorders. Here we evaluate the effects of acute exercise on Sestrin 2 (Sesn2) protein content and autophagy markers in the skeletal muscle of experimental models of aging. Twenty-four months-old C57BL/6J male mice were submitted to a single bout of swimming exercise and the gastrocnemius muscle was evaluated by Western blot. Transcriptomic and phenotypic analysis were also performed by using strains of genetically-diverse BXD mice...
July 17, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28728791/the-effects-of-achilles-tendon-compliance-on-triceps-surae-mechanics-and-energetics-in-walking
#6
Maria Isabel V Orselli, Jason R Franz, Darryl G Thelen
Achilles tendon (AT) compliance can affect the generation and transmission of triceps surae muscle forces, and thus has important biomechanical consequences for walking performance. However, the uniarticular soleus (SOL) and the biarticular (GAS) function differently during walking, with in vivo evidence suggesting that their associated fascicles and tendinous structures exhibit unique kinematics during walking. Given the strong association between muscle fiber length, velocity and force production, we conjectured that SOL and GAS mechanics and energetic behavior would respond differently to altered AT compliance...
June 29, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28728790/a-mechanistic-damage-model-for-ligaments
#7
Jeff M Barrett, Jack P Callaghan
PURPOSE: The accuracy of biomechanical models is predicated on the realism by which they represent their biomechanical tissues. Unfortunately, most models use phenomenological ligament models that neglect the behaviour in the failure region. Therefore, the purpose of this investigation was to test whether a mechanistic model of ligamentous tissue portrays behaviour representative of actual ligament failure tests. MODEL: The model tracks the time-evolution of a population of collagen fibres in a theoretical ligament...
July 11, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28728078/femoral-head-necrosis-a-finite-element-analysis-of-common-and-novel-surgical-techniques
#8
Myriam Cilla, Sara Checa, Bernd Preininger, Tobias Winkler, Carsten Perka, Georg N Duda, Matthias Pumberger
BACKGROUND: Femoral head necrosis is a common cause of secondary osteoarthritis. At the early stages, treatment strategies are normally based on core decompression techniques, where the number, location and diameter of the drilling holes varies depending on the selected approach. The purpose of this study was to investigate the risk of femoral head, neck and subtrochanteric fracture following six different core decompression techniques. MATERIALS: Five common and a newly proposed techniques were analyzed in respect to their biomechanical consequences using finite element analysis...
July 6, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28727929/na-h-exchanger-and-proton-channel-in-heart-failure-associated-with-becker-and-duchenne-muscular-dystrophy
#9
Ghassan Bkaily, Danielle Jacques
Cardiomyopathy is found in patients with Duchenne (DMD) and Becker (BMD) muscular dystrophies which are linked muscle diseases caused by mutations in the dystrophin gene. Dystrophin defects are not limited to DMD but are also present in mild BMD. The hereditary cardiomyopathic hamster of the UM-X7.1 strain is a particular experimental model of heart failure (HF) leading to early death in muscular dystrophy (dystrophin deficiency and sarcoglycan mutation) and heart disease (δ-sarcoglycan deficiency and dystrophin mutation) in human DMD...
July 20, 2017: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/28727745/evaluation-of-tissue-displacement-and-regional-strain-in-the-achilles-tendon-using-quantitative-high-frequency-ultrasound
#10
Stijn Bogaerts, Catarina De Brito Carvalho, Lennart Scheys, Kaat Desloovere, Jan D'hooge, Frederik Maes, Paul Suetens, Koen Peers
The Achilles tendon has a unique structure-function relationship thanks to its innate hierarchical architecture in combination with the rotational anatomy of the sub-tendons from the triceps surae muscles. Previous research has provided valuable insight in global Achilles tendon mechanics, but limitations with the technique used remain. Furthermore, given the global approach evaluating muscle-tendon junction to insertion, regional differences in tendon mechanical properties might be overlooked. However, recent advancements in the field of ultrasound imaging in combination with speckle tracking have made an intratendinous evaluation possible...
2017: PloS One
https://www.readbyqxmd.com/read/28725529/recent-progress-on-piezoelectric-and-triboelectric-energy-harvesters-in-biomedical-systems
#11
REVIEW
Qiang Zheng, Bojing Shi, Zhou Li, Zhong Lin Wang
Implantable medical devices (IMDs) have become indispensable medical tools for improving the quality of life and prolonging the patient's lifespan. The minimization and extension of lifetime are main challenges for the development of IMDs. Current innovative research on this topic is focused on internal charging using the energy generated by the physiological environment or natural body activity. To harvest biomechanical energy efficiently, piezoelectric and triboelectric energy harvesters with sophisticated structural and material design have been developed...
July 2017: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://www.readbyqxmd.com/read/28723948/integrative-functional-analyses-using-rainbow-trout-selected-for-tolerance-to-plant-diets-reveal-nutrigenomic-signatures-for-soy-utilization-without-the-concurrence-of-enteritis
#12
Jason Abernathy, Andreas Brezas, Kevin R Snekvik, Ronald W Hardy, Ken Overturf
Finding suitable alternative protein sources for diets of carnivorous fish species remains a major concern for sustainable aquaculture. Through genetic selection, we created a strain of rainbow trout that outperforms parental lines in utilizing an all-plant protein diet and does not develop enteritis in the distal intestine, as is typical with salmonids on long-term plant protein-based feeds. By incorporating this strain into functional analyses, we set out to determine which genes are critical to plant protein utilization in the absence of gut inflammation...
2017: PloS One
https://www.readbyqxmd.com/read/28721578/preventive-chair-massage-with-algometry-to-maintain-psychosomatic-balance-in-white-collar-workers
#13
Anna Cabak, Mirosław Mikicin, Marek Łyp, Iwona Stanisławska, Ryszard Kaczor, Wiesław Tomaszewski
People working at computers often suffer from overload-related muscle pain, and physical and mental discomfort. The aim of the study was to evaluate the effectiveness of chair massage, conducted in the workplace among white-collar workers, in relieving symptoms of musculoskeletal strain related to prolonged sitting posture. The study was conducted in 124 white-collar workers, 55 women and 69 men, aged 33.7 ± 7.6 years. Subjects were randomly assigned to three groups: chair massage program, relaxing music sessions, and a control group, each of four-week duration...
July 19, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28717620/the-influence-of-muscle-tendon-forces-on-acl-loading-during-jump-landing-a-systematic-review
#14
REVIEW
Katja Oberhofer, S H Hosseini Nasab, Pascal Schütz, Barbara Postolka, Jess G Snedeker, William R Taylor, Renate List
BACKGROUND: The goal of this review is to summarise and discuss the reported influence of muscle-tendon forces on anterior cruciate ligament (ACL) loading during the jump-landing task by means of biomechanical analyses of the healthy knee. METHODS: A systematic review of the literature was conducted using different combinations of the terms "knee", "ligament", "load", "tension ", "length", "strain", "elongation" and "lengthening". 26 original articles (n=16 in vitro studies; n=10 in situ studies) were identified which complied with all inclusion/exclusion criteria...
January 2017: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28711604/an-animal-model-of-co-existing-sarcopenia-and-osteoporotic-fracture-in-senescence-accelerated-mouse-prone-8-samp8
#15
Ning Zhang, Simon Kwoon Ho Chow, Kwok Sui Leung, Ho Hin Lee, Wing Hoi Cheung
Sarcopenia and osteoporotic fracture are common aging-related musculoskeletal problems. Recent evidences report that osteoporotic fracture patients showed high prevalence of sarcopenia; however, current clinical practice basically does not consider sarcopenia in the treatment or rehabilitation of osteoporotic fracture. There is almost no report studying the relationship of the co-existing of sarcopenia and osteoporotic fracture healing. In this study, we validated aged senescence accelerated mouse prone 8 (SAMP8) and senescence accelerated mouse resistant 1 (SAMR1) as animal models of senile osteoporosis with/without sarcopenia...
July 12, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28711025/three-dimensional-mechano-electrochemical-model-for-smooth-muscle-contraction-of-the-urinary-bladder
#16
Robert Seydewitz, Robin Menzel, Tobias Siebert, Markus Böl
The urinary bladder is a central organ of vertebrates and imposes, based on its extreme deformation (volume changes up to several 100%), special requirements on the overall bladder tissue. However, studies focusing on three-dimensional modelling of bladder deformation and bladder function during micturition are rare. Based on three fields, namely, the membrane potential, calcium concentration, and placement, a mechano-electrochemical-coupled, three-dimensional model describing the contractile behaviour of urinary bladder smooth muscle is presented using a strain energy function...
April 12, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28710834/ultrastructure-of-skeletal-muscles-in-mice-lacking-muscle-specific-vegf-expression
#17
Oliver Baum, Lena Jentsch, Adolfo Odriozola, Stefan A Tschanz, I Mark Olfert
Vascular endothelial growth factor-A (VEGF) influences several physiological processes including endothelial cell function and maintenance of organ/tissue capillarity. While the functional aspects of VEGF were vigorously investigated, only little detail is known on structural integrity of skeletal muscle fibers and capillaries in mice lacking VEGF expression in their muscles. Therefore, we assessed systematically the architecture of the glycolytic plantaris and the oxidative soleus muscles obtained from muscle-specific VEGF knockout (mVEGF-KO, n=7) mice and their wild-type (WT, n=7) littermates by morphometry after transmission electron microscopy...
July 15, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28705295/strength-training-for-women-as-a-vehicle-for-health-promotion-at-work
#18
Kai Nestler, Alexander Witzki, Ulrich Rohde, Thomas Rüther, Kim Alexander Tofaute, Dieter Leyk
BACKGROUND: Women, on average, have less muscle strength than men. This anthropometric-physiological trait may make them more vulnerable to ex - cessive physical strain, injury, and inability to work. Strength training is used for preventive health maintenance and to lessen musculoskeletal symptoms. In this context, we studied whether the degree of muscle strength has any effect on women's health in everyday working life, and also the effects of strength training for women on their health in the workplace...
June 30, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/28704177/morphology-and-contractile-gene-expression-of-adipose-derived-mesenchymal-stem-cells-in-response-to-short-term-cyclic-uniaxial-strain-and-tgf-%C3%AE-1
#19
Neda Rashidi, Mohammad Tafazzoli-Shadpour, Nooshin Haghighipour, Mohammad-Mehdi Khani
Previous studies have shown smooth muscle induction in adipose-derived mesenchymal stem cells (ASCs) caused by long-term cyclic stretch. Here we examined the capability of the short-term straining with time steps of 4, 8, 16 and 24 h alone or combined with TGF-β1 on smooth muscle induction of rabbit ASCs. Alterations in cell morphology were quantified through the cell shape index and orientation angle, and expression levels of α-SMA, SM22-α, h-caldesmon and calponin3 markers were examined using the real-time polymerase chain reaction (PCR) method...
July 12, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28698572/the-effect-of-calorie-restriction-on-mouse-skeletal-muscle-is-sex-strain-and-time-dependent
#20
Luisa Boldrin, Jacob A Ross, Charlotte Whitmore, Bruno Doreste, Charlotte Beaver, Ayad Eddaoudi, Daniel J Pearce, Jennifer E Morgan
Loss of skeletal muscle mass and function occurs with increasing age. Calorie restriction (CR) increases the lifespan of C57Bl/6 mice, but not in the shorter-lived DBA/2 strain. There is some evidence that calorie restriction reduces or delays many of the age-related defects that occur in rodent skeletal muscle. We therefore investigated the effect of short (2.5 month) and longer term (8.5 and 18.5 months) CR on skeletal muscle in male and female C57Bl/6 and DBA/2 mice. We found that short-term CR increased the satellite cell number and collagen VI content of muscle, but resulted in a delayed regenerative response to injury...
July 11, 2017: Scientific Reports
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