keyword
MENU ▼
Read by QxMD icon Read
search

strain muscle

keyword
https://www.readbyqxmd.com/read/29331367/molecular-characterization-and-differential-expression-analysis-of-interleukin-1%C3%AE-from-ovis-aries
#1
Yi-Ming Shui, Shi-Ying Lu, Xing Guo, Xi-Lin Liu, Bao-Quan Fu, Pan Hu, Lin-Lin Qu, Nan-Nan Liu, Yan-Song Li, Lu-Lu Wang, Fei-Fei Zhai, Dan-Di Ju, Zeng-Shan Liu, Yu Zhou, Hong-Lin Ren
The interleukin-1 family is an important component of the innate immune system and plays an important role in regulating immune responses on the invasion of intracellular parasites in the acquired immune system. Interleukin 1β (IL-1β) is one of the members of the IL-1 family that predominantly activates downstream signaling pathways to play immunological functions of stimulating T and B lymphocyte activation and promoting the various syntheses of inflammatory substances in conjunction with other cytokines...
January 10, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29330951/dynamic-musculoskeletal-functional-morphology-integrating-dicect-and-xromm
#2
Courtney P Orsbon, Nicholas J Gidmark, Callum F Ross
The tradeoff between force and velocity in skeletal muscle is a fundamental constraint on vertebrate musculoskeletal design (form:function relationships). Understanding how and why different lineages address this biomechanical problem is an important goal of vertebrate musculoskeletal functional morphology. Our ability to answer questions about the different solutions to this tradeoff has been significantly improved by recent advances in techniques for quantifying musculoskeletal morphology and movement. Herein, we have three objectives: (1) review the morphological and physiological parameters that affect muscle function and how these parameters interact; (2) discuss the necessity of integrating morphological and physiological lines of evidence to understand muscle function and the new, high resolution imaging technologies that do so; and (3) present a method that integrates high spatiotemporal resolution motion capture (XROMM, including its corollary fluoromicrometry), high resolution soft tissue imaging (diceCT), and electromyography to study musculoskeletal dynamics in vivo...
February 2018: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29318858/-effects-of-acupotomy-therapy-on-mrna-expressions-of-bcl-2-bax-caspase-3-in-posterior-cervical-extensor-muscles-in-cervical-spondylosis-rabbits
#3
Fu-Shui Liu, Fan-Yuan Zhou, Yi Zhang, Chang-Qing Guo
OBJECTIVE: To observe the effect of acupotomy therapy on mRNA expressions of Bcl-2, Bax , Caspase-3 in posterior cervical extensor muscles in cervical spondylosis rabbits, and explore its mechanisms for apoptosis of cervical muscles. METHODS: New Zealand rabbits were randomly divided into normal, model, electroacupuncture (EA) and acupotomy groups, 6 in each group. The cervical spondylosis model was established by forced head-bowing for a long term. After model establishment, acupotomy was used at the trapezius muscle starting point and attachment site of sternocleidomastoid muscle, etc...
December 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29317262/sensitivity-to-strain-and-shear-stress-of-isolated-mechanosensitive-enteric-neurons
#4
Eva Maria Kugler, Klaus Michel, David Kirchenbüchler, Georg Dreissen, Agnes Csiszár, Rudolf Merkel, Michael Schemann, Gemma Mazzuoli-Weber
Within the enteric nervous system, the neurons in charge to control motility of the gastrointestinal tract reside in a particular location nestled between two perpendicular muscle layers which contract and relax. We used primary cultured myenteric neurons of male guinea pigs to study mechanosensitivity of enteric neurons in isolation. Ultrafast Neuroimaging with a voltage sensitive dye technique was used to record neuronal activity in response to shear stress and strain. Strain was induced by locally deforming the elastic cell culture substrate next to a neuron...
January 6, 2018: Neuroscience
https://www.readbyqxmd.com/read/29317055/scapholunate-interosseous-ligament-dysfunction-as-a-source-of-elbow-pain-syndromes-possible-mechanisms-and-implications-for-hand-surgeons-and-therapists
#5
Cigdem Ayhan, Seval Tanrıkulu, Gursel Leblebicioglu
Elbow pain syndromes are common upper extremity musculoskeletal disorders, and they are usually associated with repetitive occupational exposure. Ligaments are often one of the sources of musculoskeletal disorders because of their mechanical and neurological properties. The wrist ligaments are some of the ligaments most vulnerable to occupational exposure. Since most occupational tasks require wrist extension for handling tools and loading, the scapholunate interosseous ligament (SLIL) bears greater strain during loading, which results in creep deformation and hysteresis...
January 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/29315914/coupling-mechanical-and-electrical-properties-in-spin-crossover-polymer-composites
#6
Sylvain Rat, Mario Piedrahita-Bello, Lionel Salmon, Gábor Molnár, Philippe Demont, Azzedine Bousseksou
Spin crossover particles of formula [Fe{(Htrz)2 (trz)}0.9 (NH2 -trz)0.3 ](BF4 )1.1 and average size of 20 nm ± 8 nm are homogeneously dispersed in poly(vinylidene fluoride-co-trifluoro-ethylene), P(VDF-TrFE), and poly(vinylidene fluoride) (PVDF) matrices to form macroscopic (cm-scale), freestanding, and flexible nanocomposite materials. The composites exhibit concomitant thermal expansion and discharge current peaks on cycling around the spin transition temperatures, i.e., new "product properties" resulting from the synergy between the particles and the matrix...
January 8, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29313270/ultrasound-elastography-based-assessment-of-the-elasticity-of-the-supraspinatus-muscle-in-impingement-syndrome-does-elastography-has-any-diagnostic-value
#7
Adnan Demirel, Murat Baykara, Tuba Tülay Koca, Ejder Berk
Ultrasound elastography (UE) is a new ultrasound-based imaging technique that provides information about elasticity and stiffness of tissues. This cross-sectional study aimed to identify the diagnostic importance of UE in supraspinatus impingement syndrome. Forty-one subjects, aged 38-70 years, were included in the study. UE was used to determine the elasticity of the supraspinatus muscle. The strain ratio was calculated as the evaluation criteria to measure the elasticity of the muscle. High strain ratio indicated low elasticity...
January 8, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29312873/left-ventricular-deformation-abnormalities-in-a-patient-with-calpainopathy-a-case-from-the-three-dimensional-speckle-tracking-echocardiographic-magyar-path-study
#8
Attila Nemes, Lívia Dézsi, Péter Domsik, Anita Kalapos, Tamás Forster, László Vécsei
Calpainopathy or limb-girdle muscular dystrophy type 2A (LGMD2A) is the most common type of autosomal recessive limb-girdle muscular dystrophies. The disease is caused by mutations in the CAPN3 gene encoding calpain, a protein involved in muscle membrane remodeling and repair. This paper gives an overview of the genetic background, clinical course, and diagnosis of the disease, and presents the first case of calpainopathy in which cardiac deformation mechanics was investigated. Three-dimensional speckle-tracking echocardiography (3DSTE) demonstrated reduced left ventricular (LV) strains and increased LV apical rotation and twist, suggestive of asymptomatic subclinical LV dysfunction...
December 2017: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29307686/purified-protein-derivative-skin-test-prior-to-bacillus-calmette-gu%C3%A3-rin-therapy-may-have-therapeutic-impact-in-patients-with-non-muscle-invasive-bladder-cancer
#9
Naoya Niwa, Eiji Kikuchi, Kazuhiro Matsumoto, Takeo Kosaka, Ryuichi Mizuno, Mototsugu Oya
PURPOSE: To investigate the clinical impact of the purified protein derivative (PPD) skin test prior to bacillus Calmette-Guérin (BCG) therapy in patients with non-muscle-invasive bladder cancer (NMIBC) treated with adjuvant BCG therapy. MATERIALS AND METHODS: A total of 498 NMIBC patients treated with adjuvant BCG therapy were included, among which 320 received the PPD skin test 1 to 2 weeks prior to BCG therapy. Oncological outcomes and the rate of BCG-related side effects were statistically evaluated...
January 4, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29306866/mechanical-stress-potentiates-the-differentiation-of-periodontal-ligament-stem-cells-into-keratocytes
#10
Jialin Chen, Wei Zhang, Ludvig J Backman, Peyman Kelk, Patrik Danielson
AIMS: To explore the role of corneal-shaped static mechanical strain on the differentiation of human periodontal ligament stem cells (PDLSCs) into keratocytes and the possible synergistic effects of mechanics and inducing medium. METHODS: PDLSCs were exposed to 3% static dome-shaped mechanical strain in a Flexcell Tension System for 3 days and 7 days. Keratocyte phenotype was determined by gene expression of keratocyte markers. Keratocyte differentiation (inducing) medium was introduced in the Flexcell system, either continuously or intermittently combined with mechanical stimulation...
January 6, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29288355/ucs-protein-function-is-partially-restored-in-the-saccharomyces-cerevisiae-she4-mutant-with-expression-of-the-human-unc45-gc-but-not-unc45-sm
#11
Susana Gómez Escalante, Joseph A Brightmore, Peter W Piper, Stefan H Millson
A dedicated UNC45, Cro1, She4 (UCS) domain-containing protein assists in the Hsp90-mediated folding of the myosin head. Only weak sequence conservation exists between the single UCS protein of simple eukaryotes (She4 in budding yeast) and the two UCS proteins of higher organisms (the general cell and striated muscle UNC45s; UNC45-GC and UNC45-SM, respectively). In vertebrates, UNC45-GC facilitates cytoskeletal functions, whereas the 55% identical UNC45-SM assists assembly of the contractile apparatus of cardiac and skeletal muscles...
December 29, 2017: Cell Stress & Chaperones
https://www.readbyqxmd.com/read/29286554/effect-of-intravenous-administration-of-cobalt-chloride-to-horses-on-clinical-and-hemodynamic-variables
#12
T A Burns, K A Dembek, A Kamr, S B Dooley, L K Dunbar, T K Aarnes, L S Bednarski, C O'Brien, J Lakritz, B Byrum, A Wade, R Farmer, S Tan, R E Toribio
BACKGROUND: Cobalt chloride (CoCl2 ) is administered to racehorses to enhance performance. The purpose of this study was to evaluate the clinical, cardiovascular, and endocrine effects of parenterally administered CoCl2 . OBJECTIVES: To describe the effects of weekly intravenous doses of CoCl2 on Standardbred horses. ANIMALS: Five, healthy Standardbred mares. METHODS: Prospective, randomized, experimental dose-escalation pilot...
December 29, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29284661/effect-of-ibuprofen-on-skeletal-muscle-of-dysferlin-null-mice
#13
Alyssa F Collier, Jessica Gumerson, Jace W Jones, Maureen A Kane, Kimmo Lehtimaki, Jukka Puolivali, Sankeerth Manne, Andrea O'Neill, Hillarie P Windish, Toni Ahtoniemi, Bradley A Williams, Douglas E Albrecht, Robert J Bloch
Ibuprofen, a non-steroidal anti-inflammatory drug, and nitric oxide (NO) donors have been reported to reduce the severity of muscular dystrophies in mice associated with the absence of dystrophin or α-sarcoglycan, but their effects on mice that are dystrophic due to the absence of dysferlin have not been examined. We have tested ibuprofen, as well as isosorbide dinitrate (ISDN), an NO donor, to learn if used alone or together they protect dysferlin-null muscle in A/J mice from large strain injury (LSI) induced by a series of high strain lengthening contractions...
December 28, 2017: Journal of Pharmacology and Experimental Therapeutics
https://www.readbyqxmd.com/read/29282065/pulmonary-edema-following-central-nervous-system-lesions-induced-by-a-non-mouse-adapted-ev71-strain-in-neonatal-balb-c-mice
#14
Yuefei Jin, Chao Zhang, Rongguang Zhang, Jingchao Ren, Shuaiyin Chen, Meili Sui, Guangyuan Zhou, Dejian Dang, Jiehui Zhu, Huifen Feng, Yuanlin Xi, Haiyan Yang, Guangcai Duan
BACKGROUND: Enterovirus (EV) infection has been a serious health issue in Asia-Pacific region. It has been indicated that the occurrence of fatal hand foot and mouth disease (HFMD) cases following EV71 infection is mainly attributed to pulmonary edema. However, the development of pulmonary disorders after EV71 infection remains largely unknown. To establish an EV71-infected animal model and further explore the underlying association of central nervous system (CNS) invasion with pulmonary edema, we isolated a clinical source EV71 strain (ZZ1350) from a severe case in Henan Province...
December 28, 2017: Virology Journal
https://www.readbyqxmd.com/read/29281768/genome-characterization-of-piscine-scale-drop-and-muscle-necrosis-syndrome-associated-strain-of-vibrio-harveyi-focusing-on-bacterial-virulence-determinants
#15
Pattanapon Kayansamruaj, Ha Thanh Dong, Ikuo Hirono, Hidehiro Kondo, Saengchan Senapin, Channarong Rodkhum
AIMS: Genomic characterization of Harveyi clade vibrio strain Y6 causing 'Scale drop and Muscle Necrosis syndrome' (SDMN) isolated from barramundi (Lates calcarifer) in Vietnam. METHODS AND RESULTS: A bacterial genome was sequenced using Illumina MiSeq platform. Multilocus sequence analysis confirmed that the bacterium belongs to Vibrio harveyi species. Further phylogenetic analysis inferred from core genome SNPs revealed a close relationship between our bacterium and the V...
December 27, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29280520/significance-of-isolated-papillary-muscle-hypertrophy-a-comparison-of-left-ventricular-hypertrophy-diagnosed-using-electrocardiography-vs-echocardiography
#16
Namiko Nomura, Tomoko Tani, Toshiko Konda, Kitae Kim, Takeshi Kitai, Natsumi Nomoto, Naoko Suganuma, Hitomi Nakamura, Toshiaki Sumida, Yoko Fujii, Junichi Kawai, Shuichiro Kaji, Yutaka Furukawa
AIMS: The clinical significance of papillary muscle hypertrophy and its electrocardiography (ECG) findings has not been fully elucidated. This study aimed to investigate the relationship between ECG findings and papillary muscle hypertrophy and to confirm the importance of papillary muscle measurements on transthoracic echocardiography (TTE). METHODS AND RESULTS: Of the 237 consecutive patients who showed left ventricular hypertrophy (LVH) pattern on a 12-lead ECG, TTE data were available for 101 patients...
December 27, 2017: Echocardiography
https://www.readbyqxmd.com/read/29278079/regional-and-age-dependent-residual-strains-curvature-and-dimensions-of-the-human-ureter
#17
Despoina C Petsepe, Stavros K Kourkoulis, Stavroula A Papadodima, Dimitrios P Sokolis
The ureters are retroperitoneal structures controlling urine transport from the kidneys to the bladder. Because of the relative scarcity of data on the biomechanical properties of human ureter and the established importance of knowing these properties for understanding its physiology, we initiated biomechanical studies in cadaveric tissue. Herein, we report definite zero-stress/no-load geometrical characterization at 15 regions along the ureter of human cadavers aged 23-82 years, estimating the opening angle, circumferential residual strains, axial curvature, and dimensional parameters...
December 1, 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/29277040/associations-of-components-of-sarcopenic-obesity-with-bone-health-and-balance-in-older-adults
#18
David Scott, Catherine Shore-Lorenti, Lachlan McMillan, Jakub Mesinovic, Ross A Clark, Alan Hayes, Kerrie M Sanders, Gustavo Duque, Peter R Ebeling
OBJECTIVES: To determine characteristics of sarcopenic obesity that are independently associated with bone health and balance in older adults. STUDY DESIGN: Cross-sectional study of 168 community-dwelling older adults (mean age 67.7 ± 8.4 years; 55% women). MAIN OUTCOME MEASURES: Appendicular lean mass (ALM), whole-body areal BMD (aBMD) and body fat percentage were assessed by dual-energy X-ray absorptiometry. Peripheral quantitative computed tomography assessed muscle density and cortical volumetric BMD (vBMD), area, thickness, and strength-strain index (SSI) at 66% tibial length...
December 16, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29276759/in-vivo-multiscale-and-spatially-dependent-biomechanics-reveals-differential-strain-transfer-hierarchy-in-skeletal-muscle
#19
Soham Ghosh, James G Cimino, Adrienne K Scott, Frederick W Damen, Evan H Phillips, Alexander I Veress, Corey P Neu, Craig J Goergen
Biological tissues have a complex hierarchical architecture that spans organ to subcellular scales and comprises interconnected biophysical and biochemical machinery. Mechanotransduction, gene regulation, gene protection, and structure-function relationships in tissues depend on how force and strain are modulated from macro to micro scales, and vice versa. Traditionally, computational and experimental techniques have been used in common model systems (e.g., embryos) and simple strain measures were applied. But the hierarchical transfer of mechanical parameters like strain in mammalian systems is largely unexplored in vivo...
November 13, 2017: ACS Biomaterials Science & Engineering
https://www.readbyqxmd.com/read/29276603/varicose-vein-appearance-caused-by-perforating-vein-incompetence-detected-after-intense-cycling
#20
Charlotte E Davies, Angie M White, Mark S Whiteley
The role of incompetent perforating veins in the aetiology of varicose veins is not well understood. Anecdotally, competitive cyclists appeared to be more prone to varicose veins than the general population. We present a case of a 63-year-old amateur competitive cyclist who acutely developed a painful varicosity of her left calf while straining during a hill climb in 106-mile cycle race. Duplex ultrasonography has shown an underlying incompetent perforating vein, feeding the varicosity directly through the underlying muscle...
2017: SAGE open medical case reports
keyword
keyword
34140
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"