keyword
MENU ▼
Read by QxMD icon Read
search

Looi

keyword
https://www.readbyqxmd.com/read/27905023/distinct-cortical-and-sub-cortical-neurogenic-domains-for-gabaergic-interneuron-precursor-transcription-factors-nkx2-1-olig2-and-coup-tfii-in-early-fetal-human-telencephalon
#1
Ayman Alzu'bi, Susan Lindsay, Janet Kerwin, Shi Jie Looi, Fareha Khalil, Gavin J Clowry
The extent of similarities and differences between cortical GABAergic interneuron generation in rodent and primate telencephalon remains contentious. We examined expression of three interneuron precursor transcription factors, alongside other markers, using immunohistochemistry on 8-12 post-conceptional weeks (PCW) human telencephalon sections. NKX2.1, OLIG2, and COUP-TFII expression occupied distinct (although overlapping) neurogenic domains which extended into the cortex and revealed three CGE compartments: lateral, medial, and ventral...
November 30, 2016: Brain Structure & Function
https://www.readbyqxmd.com/read/27888241/neuropsychiatry-a-synthesis-of-clinical-and-scientific-fields-for-disorders-of-mind-and-body
#2
EDITORIAL
Jeffrey Cl Looi
No abstract text is available yet for this article.
December 2016: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/27801388/a-review-of-stroke-research-in-malaysia-from-2000-2014
#3
W K Cheah, C P Hor, A A Zariah, I Looi
Over 100 articles related to stroke were found in a search through a database dedicated to indexing all literature with original data involving the Malaysian population between years 2000 and 2014. Stroke is emerging as a major public health problem. The development of the National Stroke Registry in the year 2009 aims to coordinate and improve stroke care, as well as to generate more data on various aspects of stroke in the country. Studies on predictors of survival after strokes have shown potential to improve the overall management of stroke, both during acute event and long term care...
June 2016: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/27775047/repetitive-electroacupuncture-attenuates-cold-induced-hypertension-through-enkephalin-in-the-rostral-ventral-lateral-medulla
#4
Min Li, Stephanie C Tjen-A-Looi, Zhi-Ling Guo, John C Longhurst
Acupuncture lowers blood pressure (BP) in hypertension, but mechanisms underlying its action are unclear. To simulate clinical studies, we performed electroacupuncture (EA) in unanesthetized rats with cold-induced hypertension (CIH) induced by six weeks of cold exposure (6 °C). EA (0.1 - 0.4 mA, 2 Hz) was applied at ST36-37 acupoints overlying the deep peroneal nerve for 30 min twice weekly for five weeks while sham-EA was conducted with the same procedures as EA except for no electrical stimulation...
October 24, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27760460/role-of-electrochemistry-in-desorption-ionization-mass-spectrometry-ls-desi-ms-of-aqueous-samples-containing-electrolyte-salts
#5
Wen Donq Looi, Laura Chamand, Blake Brown, Anna F Brajter-Toth
The ionization of liquid samples in desorption ionization mass spectrometry (LS DESI MS), supplied continuously through a liquid interface separated in space from the spray emitter, was investigated in this work. The role of electrochemistry (EC) in the ionization process was addressed. The visual (observation) of the operation of the LS DESI MS system showed a thick spray plume generated by electrosonic ionization (ESSI) forming a liquid cone at the liquid interface. When the liquid interface was grounded the cone collapsed and the MS ion signal was lost, indicating that the LS was carried to the MS inlet by the spray that emerged from the cone...
October 20, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/27750041/paracrine-il-6-signaling-mediates-the-effects-of-pancreatic-stellate-cells-on-epithelial-mesenchymal-transition-via-stat3-nrf2-pathway-in-pancreatic-cancer-cells
#6
Yuan Seng Wu, Ivy Chung, Won Fen Wong, Atsushi Masamune, Maw Shin Sim, Chung Yeng Looi
BACKGROUND: We previously showed that pancreatic stellate cells (PSC) secreted interleukin (IL)-6 and promoted pancreatic ductal adenocarcinoma (PDAC) cell proliferation via nuclear factor erythroid 2 (Nrf2)-mediated metabolic reprogramming. Epithelial-mesenchymal transition (EMT) is a key process for the metastatic cascade. To study the mechanism of PDAC progression to metastasis, we investigated the role of PSC-secreted IL-6 in activating EMT and the involvement of Nrf2 in this process...
October 14, 2016: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27729850/an-in-vivo-multi-modal-structural-template-for-neonatal-piglets-using-high-angular-resolution-and-population-based-whole-brain-tractography
#7
Jidan Zhong, David Q Chen, Matthew Walker, Adam Waspe, Thomas Looi, Karolina Piorkowska, James M Drake, Mojgan Hodaie
An increasing number of applications use the postnatal piglet model in neuroimaging studies, however, these are based primarily on T1 weighted image templates. There is a growing need for a multimodal structural brain template for a comprehensive depiction of the piglet brain, particularly given the growing applications of diffusion weighted imaging for characterizing tissue microstructures and white matter organization. In this study, we present the first multimodal piglet structural brain template which includes a T1 weighted image with tissue segmentation probability maps, diffusion weighted metric templates with multiple diffusivity maps, and population-based whole-brain fiber tracts for postnatal piglets...
2016: Frontiers in Neuroanatomy
https://www.readbyqxmd.com/read/27726456/effect-of-human-rhinovirus-infection-on-airway-epithelium-tight-junction-protein-disassembly-and-transepithelial-permeability
#8
Kevin Looi, Niamh M Troy, Luke W Garratt, Thomas Iosifidis, Anthony Bosco, Alysia G Buckley, Kak-Ming Ling, Kelly M Martinovich, Elizabeth Kicic-Starcevich, Nicole C Shaw, Erika N Sutanto, Graeme R Zosky, Paul J Rigby, Alexander N Larcombe, Darryl A Knight, Anthony Kicic, Stephen M Stick
RATIONALE: No studies have assessed the effects of human rhinovirus (HRV) infection on epithelial tight junctions (TJs) and resultant barrier function. AIM OF THE STUDY: To correlate viral infection with TJ disassembly, epithelial barrier integrity, and function. MATERIALS AND METHODS: Human airway epithelial cells were infected with HRV minor serotype 1B (HRV-1B) at various 50% tissue culture infectivity doses (TCID50) over 72 hours. HRV replication was assessed by quantitative-polymerase chain reaction (qPCR) while cell viability and apoptosis were assessed by proliferation and apoptotic assays, respectively...
October 11, 2016: Experimental Lung Research
https://www.readbyqxmd.com/read/27681025/alignment-of-governance-and-senior-executive-perceptions-of-culture
#9
Evelyn Suk Yi Looi, Richard Greatbanks, André M Everett
Purpose The purpose of this paper is to examine the alignment of perceived organizational culture between Health Board chairs and Board members with that of their respective senior executive teams. It compares the degree of alignment between these two groups, and analyses them against District Health Board (DHB) performance using the New Zealand Ministry of Health's national measure "shorter stays in Emergency Departments." Design/methodology/approach Primary survey data were collected across eight DHBs using a modified version of the Organizational Culture Assessment Instrument and utilizes a sample of both higher and lower performing DHBs as defined by the "shorter stays" measure...
September 19, 2016: Journal of Health Organization and Management
https://www.readbyqxmd.com/read/27673709/family-impact-and-infant-emotional-outcomes-following-diagnosis-of-serious-liver-disease-or-transplantation-in-infancy
#10
Michael R Bowden, Looi C Ee, Usha Krishnan, Edward V O'Loughlin, Winita Hardikar, Diana Carmody, Cassandra Hainsworth, Vicki Jermyn, Mee-Mee Lee, Janine Sawyer, Michael Stormon, Kathe Holmes, Daniel A Lemberg, Andrew S Day, Campbell Paul, Philip Hazell
OBJECTIVES: Research is lacking into the emotional effects on families of serious chronic illness in infants. We examined the impact of the diagnosis of serious liver disease in infants upon parent psychological symptoms and family functioning. We hypothesized that parent psychological symptoms, family functioning and father engagement will predict infant emotional outcomes. METHODS: Parents of infants recently diagnosed with serious liver disease completed validated questionnaires about parent stress, family function, impact of the illness on the family, and father engagement...
September 24, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27607083/adherence-to-the-current-guidelines-for-bradycardic-pacing-in-the-octogenarian-and-nonagenarian-populations
#11
Vivienne Kim, James Pemberton, Fiona Riddell, Khang-Li Looi
AIM: A significant proportion of single-chamber ventricular pacemakers are implanted in octogenarian and nonagenarian patients. We aimed to assess whether the current pacing guideline is adhered for these populations. METHODS: We retrospectively identified patients ≥80 years of age, who received their first pacemaker from July 2010 to June 2013. RESULTS: A total of 356 patients were identified. Mean age was 86.1 years and 82.6 years for single and dual-chamber pacemakers respectively (p<0...
2016: New Zealand Medical Journal
https://www.readbyqxmd.com/read/27598341/assessment-of-telomere-length-in-archived-formalin-fixed-paraffinized-human-tissue-is-confounded-by-chronological-age-and-storage-duration
#12
Po-Lian Kong, Lai-Meng Looi, Tze-Pheng Lau, Phaik-Leng Cheah
Telomeres shorten with physiological aging but undergo substantial restoration during cancer immortalization. Increasingly, cancer studies utilize the archive of formalin-fixed, paraffin-embedded (FFPE) tissues in diagnostic pathology departments. Conceptually, such studies would be confounded by physiological telomere attrition and loss of DNA integrity from prolonged tissue storage. Our study aimed to investigate these two confounding factors. 145 FFPE tissues of surgically-resected, non-diseased appendixes were retrieved from our pathology archive, from years 2008 to 2014...
2016: PloS One
https://www.readbyqxmd.com/read/27587029/design-and-validation-of-an-mr-conditional-robot-for-transcranial-focused-ultrasound-surgery-in-infants
#13
Karl D Price, Vivian W Sin, Charles Mougenot, Samuel Pichardo, Thomas Looi, Adam C Waspe, James M Drake
PURPOSE: Current treatment of intraventricular hemorrhage (IVH) involves cerebral shunt placement or an invasive brain surgery. Magnetic resonance-guided focused ultrasound (MRgFUS) applied to the brains of pediatric patients presents an opportunity to treat IVH in a noninvasive manner, termed "incision-less surgery." Current clinical and research focused ultrasound systems lack the capability to perform neonatal transcranial surgeries due to either range of motion or dexterity requirements...
September 2016: Medical Physics
https://www.readbyqxmd.com/read/27568677/erratum-phyllodes-tumours-of-the-breast-retrospective-analysis-of-a-university-hospital-s-experience
#14
Y F Toh, P L Cheah, L M Looi, K H Teoh, P H Tan
No abstract available.
August 2016: Malaysian Journal of Pathology
https://www.readbyqxmd.com/read/27510230/targeting-multiple-oncogenic-pathways-for-the-treatment-of-hepatocellular-carcinoma
#15
Supritha G Swamy, Vivek H Kameshwar, Priya B Shubha, Chung Yeng Looi, Muthu K Shanmugam, Frank Arfuso, Arunasalam Dharmarajan, Gautam Sethi, Nanjunda Swamy Shivananju, Anupam Bishayee
Hepatocellular carcinoma (HCC) is one of the most common forms of liver cancer diagnosed worldwide. HCC occurs due to chronic liver disease and is often diagnosed at advanced stages. Chemotherapeutic agents such as doxorubicin are currently used as first-line agents for HCC therapy, but these are non-selective cytotoxic molecules with significant side effects. Sorafenib, a multi-targeted tyrosine kinase inhibitor, is the only approved targeted drug for HCC patients. However, due to adverse side effects and limited efficacy, there is a need for the identification of novel pharmacological drugs beyond sorafenib...
August 11, 2016: Targeted Oncology
https://www.readbyqxmd.com/read/27502829/differentiating-sibling-species-of-zeugodacus-caudatus-insecta-tephritidae-by-complete-mitochondrial-genome
#16
Hoi-Sen Yong, Sze-Looi Song, Phaik-Eem Lim, Praphathip Eamsobhana, I Wayan Suana
Zeugodacus caudatus is a pest of pumpkin flowers. It has a Palearctic and Oriental distribution. We report here the complete mitochondrial genome of the Malaysian and Indonesian samples of Z. caudatus determined by next-generation sequencing of genomic DNA and determine their taxonomic status as sibling species and phylogeny with other taxa of the genus Zeugodacus. The whole mitogenome of both samples possessed 37 genes (13 protein-coding genes-PCGs, 2 rRNA and 22 tRNA genes) and a control region. The mitogenome of the Indonesian sample (15,885 bp) was longer than that of the Malaysian sample (15,866 bp)...
October 2016: Genetica
https://www.readbyqxmd.com/read/27456351/neuropsychiatric-manifestations-of-parkinson-s-disease
#17
Rosa M Molina Ruiz, Andrew H Evans, Dennis Velakoulis, Jeffrey Cl Looi
OBJECTIVE: This clinical update review focuses on the classification and description of common neuropsychiatric manifestations in Parkinson's disease (PD). METHOD: We conducted a systematic search of the literature using Pubmed and selected the most recent and relevant papers for this review. RESULTS: Neuropsychiatric manifestations in PD are are very frequent and may arise from an abnormal psychopathological response to the disease, neurobiological changes related to the disease itself, complications of treatments or a combination of all of these...
July 25, 2016: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/27386357/natural-deep-eutectic-solvents-cytotoxic-profile
#18
Maan Hayyan, Yves Paul Mbous, Chung Yeng Looi, Won Fen Wong, Adeeb Hayyan, Zulhaziman Salleh, Ozair Mohd-Ali
The purpose of this study was to investigate the cytotoxic profiles of different ternary natural deep eutectic solvents (NADESs) containing water. For this purpose, five different NADESs were prepared using choline chloride as a salt, alongside five hydrogen bond donors (HBD) namely glucose, fructose, sucrose, glycerol, and malonic acid. Water was added as a tertiary component during the eutectics preparation, except for the malonic acid-based mixture. Coincidentally, the latter was found to be more toxic than any of the water-based NADESs...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27339019/brain-stimulation-mathematical-and-numerical-training-contribution-of-core-and-noncore-skills
#19
C Y Looi, R Cohen Kadosh
Mathematical abilities that are correlated with various life outcomes vary across individuals. One approach to improve mathematical abilities is by understanding the underlying cognitive functions. Theoretical and experimental evidence suggest that mathematical abilities are subserved by "core" and "noncore" skills. Core skills are commonly regarded as the "innate" capacity to attend to and process numerical information, while noncore skills are those that are important for mathematical cognition, but are not exclusive to the mathematical domain such as executive functions, spatial skills, and attention...
2016: Progress in Brain Research
https://www.readbyqxmd.com/read/27329644/affective-disorders-and-functional-non-epileptic-seizures-in-persons-with-epilepsy
#20
Keith A Johnson, Matthew D Macfarlane, Jeffrey Cl Looi
OBJECTIVE: This paper aims to describe the prevalence, assessment and management of affective disorders as well as functional (non-epileptic) seizures in people with epilepsy. METHOD: This paper comprises a selective review of the literature of the common affective manifestations of epilepsy. RESULTS: Affective disorders are the most common psychiatric comorbidity seen in people with epilepsy and assessment and management parallels that of the general population...
June 21, 2016: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
keyword
keyword
3413
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"