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vascular prosthesis

Madathipat Unnikrishnan, P R Umashankar, Sidharth Viswanathan, Ajay Savlania, Roy Joseph, C V Muraleedharan, Vivek Agrawal, Sachin J Shenoy, Lissy K Krishnan, P V Mohanan, A Sabareeswaran
Background & objectives: Polyethylene terephthalate (PET) graft, designed and developed at our institute for vascular reconstruction, is porous to promote optimal incorporation and neointima formation, requiring pre-clotting or biomodification by sealing the pores before implantation. The objective of this study was to characterize, test and perform preclinical evaluation of hydrogel (alginate dialdehyde cross-linked gelatin) sealed fluoropassivated PET vascular prosthesis in pig model, so as to avoid pre-clotting, for its safety and efficacy before employing the indigenous and less expensive graft for clinical use...
November 2017: Indian Journal of Medical Research
Mathieu van Steenberghe, Thomas Schubert, Caroline Bouzin, Carlo Caravaggio, Yves Guiot, Daela Xhema, Pierre Gianello
BACKGROUND: There is a need for small caliber vascular prosthesis. Synthetic grafts are hindered by thrombogenicity and rapid occlusion. Decellularized matrices could be an alternative. We assessed in vitro and in vivo the biocompatibility of porcine artery treated with a chemical/physical process for decellularization and graft securization with non/conventional pathogens inactivation. METHODS: Porcine carotid arteries (PCA) were treated. First, biopsies (n=4/tissue) were performed before/after treatment to assess decellularization (HE / DAPI / DNA / Miller)...
February 28, 2018: Annals of Vascular Surgery
Bruno Zanotti, Nicola Zingaretti, Angela Verlicchi, Alex Alfieri, Pier Camillo Parodi
When a cranioplasty implant becomes infected, standard operating procedure dictates its removal and the initiation of a long course of antibiotic therapy. However, removing such a prosthesis can have a series of adverse consequences, including delayed cognitive and motor recovery, lack of brain tissue protection, unsightly deformity, and the need for two additional surgical procedures, not to mention the additional costs involved. To maintain the advantages of cranioplasty, we opted for a conservative approach (levofloxacin and rifampicin every 24 hours for 8 weeks) in a 68-year-old woman whose custom-made porous hydroxyapatite implant, fitted following aneurysm clipping, had become infected...
March 1, 2018: Journal of Craniofacial Surgery
Guan-Yi Liu, Ling-Yong Jing, Zhi-Jun Pan, Long-Jun Chen, Ming Li, Jian-Xiang Feng, Wei-Hu Ma
OBJECTIVE: To explore the clinical outcomes of internal fixation or replacement for the treatment of radial head fractures through the extensor digitorum communis splitting approach. METHODS: From July 2012 to May 2015, 25 patients with radial head fractures were reviewed. There were 17 males and 8 females, ranging in age from 20 to 67 years old, with a mean age of 39 years old. Twenty-one patients were treated with reconstruction of plate internal fixation, and 4 patients were treated with radial head replacement...
November 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
Cynthia Aristei, Orit Kaidar-Person, Luca Tagliaferri, Meritxell Arenas, Charlotte E Coles, Birgitte V Offersen, Giovanni Frezza, Maria Cristina Leonardi, Vincenzo Valentini, Céline Bourgier, Philip M P Poortmans
PURPOSE: To describe the current European practise on post-mastectomy radiation therapy (PMRT) in relation to breast reconstruction. METHODS: A 21-item questionnaire was distributed online via Survey Monkey. Items referred to 1. general topics (country, centre, years of experience in breast cancer); 2. clinical decision making; 3. RT techniques and dosimetry; 4. dose fractionation. RESULTS: 283 responses were received from 19 countries. Most responders worked in public health services and in academic institutions and had 5-20 years experience...
January 12, 2018: European Journal of Surgical Oncology
Bin-Fei Zhang, Yu-Xuan Cong, Peng-Fei Wang, Hai Huang, Hu Wang, Yan Zhuang
INTRODUCTION: Complications involving vascular injuries after hip fracture are rare, and the diagnosis and management of deep femoral artery (DFA) injuries are challenging. We reported 4 cases of DFA injuries after hip fracture surgery and aimed to discuss their early detection, treatment, and prevention. METHODS: We reviewed 4 cases of deep femoral injury after hip fracture. Case 1: a 71-year-old woman suffered a fracture around a prosthesis. Cases 2-4: 2 men and 1 woman suffered subtrochanteric or intertrochanteric fracture...
February 2018: Medicine (Baltimore)
Jigang Lou, Beiyu Wang, Tingkui Wu, Wenjie Wu, Huibo Li, Ziyang Liu, Hao Liu
BACKGROUND: A study was designed to quantify the extent of porous osseointegration at the prosthesis-bone interface in the Prestige LP prosthesis containing a plasma-sprayed titanium coating. METHODS: Using an anterior surgical approach, cervical disc arthroplasty was performed in 8 mature male goats at the C3-C4 segment, followed by implantation of the Prestige LP prosthesis. The vertebral specimens were examined using microcomputed tomograph for histomorphometric quantification, and proceeded by routine paraffin processing for histological observation...
February 7, 2018: BMC Musculoskeletal Disorders
Alicia M Quesnel, Reuven Ishai, Michael J McKenna
Otosclerosis is pathologically characterized by abnormal bony remodeling, which includes bone resorption, new bone deposition, and vascular proliferation in the temporal bone. Sensorineural hearing loss in otosclerosis is associated with extension of otosclerosis to the cochlear endosteum and deposition of collagen throughout the spiral ligament. Persistent or recurrent conductive hearing loss after stapedectomy has been associated with incomplete footplate fenestration, poor incus-prosthesis connection, and incus resorption in temporal bone specimens...
February 2, 2018: Otolaryngologic Clinics of North America
Masaaki Karino, Takahiro Kanno, Ichiro Kaneko, Taichi Ide, Aya Yoshino, Joji Sekine
We usually perform surgery for resectable oral and maxillofacial carcinomas. Following complete cancer resection, reconstruction of soft and hard tissues using various types of local flaps and/or vascularized free flaps is usually performed. The maxilla is composed of various anatomical structures. In particular, reconstruction of the orbit is one of the most important and challenging procedures for prevention of functional and esthetic complications. Here we report 2 cases of orbital floor defect reconstruction following advanced maxillary cancer resection using a pedicled coronoid process and temporal muscle (fascial)combined(PCPTM)flap...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Peiji Wang, Man-Yi Cui, Jiaju Zhao, Jun Lv
RATIONALE: Serious external ankle injuries caused by high-energy trauma are often associated not only with bone defect but also with a loss of skin and soft tissue that seriously affects ankle function. Therefore, it is particularly important to reconstruct the external ankle. PATIENT CONCERNS: The patient was a 64-year-old man with destructive injury of both lower extremities due to a machine accident. His left ankle and heel bone, along with the soft tissue, were torn off, and the peripheral blood supply and sensation to the toes of the left foot were lost concerns...
December 2017: Medicine (Baltimore)
Xucheng Yang, Yingying Zhang, Yusheng Li, Ting Wen
Osteolysis associated with an implanted prosthesis is the major cause of failure in prosthesis implantation, and a severe public health issue worldwide. The type of bone metabolism associated with this disorder has been a major focus for improving the outcomes of patients with osteolysis. The role of metastasis‑associated lung adenocarcinoma transcript 1 (MALAT1; a member of the long coding RNA family) during the onset of osteolysis and the related molecular regulatory mechanism in ultra‑high molecular weight polyethylene (UHMWPE)‑treated hFOB 1...
January 4, 2018: International Journal of Molecular Medicine
Kashish Goel, David R Holmes
Transcatheter aortic valve replacement (TAVR) has been approved in the United States for intermediate and high-risk patients with severe symptomatic aortic stenosis. More than 80 000 TAVR procedures have been performed in the United States and the number is growing every year. Two valve designs are approved in the United States including the balloon expandable Edwards Sapien prosthesis and self-expanding CoreValve prosthesis. The PARTNER trial of the Sapien valve, involving patients who were considered inoperable, reported a 19% absolute risk reduction in mortality compared with medical therapy, with a number needed to treat of 5...
December 14, 2017: Journal of Cardiopulmonary Rehabilitation and Prevention
Achim Neufang, Christine Espinola-Klein, Savvas Savvidis, Walther Schmiedt, Alicia Poplawski, Christian Friedrich Vahl, Bernhard Dorweiler
OBJECTIVE: Use of autologous veins as peripheral bypass graft may become critical in the presence of significant varicose degeneration of the harvested vein. External support of such dilated veins with standard polytetrafluoroethylene (PTFE) prostheses was recommended as an option to use these veins for peripheral bypass. A single-center experience with this technique regarding long-term graft function, secondary reinterventions, and potential graft degeneration is presented. METHODS: Between January 1995 and January 2006, there were 54 patients with varicose veins who underwent 57 consecutive infrainguinal vein bypass operations with PTFE reinforcement in 57 limbs...
December 11, 2017: Journal of Vascular Surgery
Luiz Eduardo Moreira Teixeira, Thiago Marques Leão, Daniel Barbosa Regazzi, Cláudio Beling Gonçalves Soares
Objective: The objective of this study is to evaluate the efficacy of vascular reconstructive surgery after resection of bone and soft tissue tumors in extremities and the risk of progression to amputation. Methods: This is a retrospective, observational data collection from medical records of patients who underwent resection of bone and soft tissue tumors in the period of 2002-2015. Thirteen patients met the inclusion criteria, which evaluated the correlations between certain factors (gender, tumor type, location, reconstruction, revascularization and patency, infection) with amputation in the postoperative period...
November 2017: Revista Brasileira de Ortopedia
E Brauner, A Quarato, F De Angelis, G Pompa, S Jamshir, V Valentini, S Di Carlo
INTRODUCTION: Osteosarcoma is an aggressive primary bone tumor composed of connective tissue cells directly producing osteoid and bone. Prosthetic rehabilitations in post-oncological patients after bone reconstruction are not substantially different than those of patients affected by severe atrophy of upper or lower jaw after bone reconstruction. The treatment for patients with a malignant neoplasia of the oral cavity requires multidisciplinary approach by a team of different specialists that follow the patient through the phases of diagnosis, therapy and oral rehabilitation...
November 2017: La Clinica Terapeutica
Sergio M Borghi, Sandra S Mizokami, Felipe A Pinho-Ribeiro, Victor Fattori, Jefferson Crespigio, Juliana T Clemente-Napimoga, Marcelo H Napimoga, Dimitrius L Pitol, João P M Issa, Sandra Y Fukada, Rubia Casagrande, Waldiceu A Verri
Titanium dioxide (TiO2 ) is a common component of orthopedic prosthesis. However, prosthesis wear releases TiO2 , which induces inflammation and osteolysis in peri-prosthetic tissues. Quercetin is a flavonoid widely present in human diet, which presents biological activities such as antinociceptive, anti-inflammatory and antioxidant effects. Therefore, the effect of intraperitoneal treatment with quercetin in TiO2 -induced arthritis model was evaluated. In the first set of experiments, mice received injection of TiO2 (0...
March 2018: Journal of Nutritional Biochemistry
Ayepa Alain Kouadio, Fabienne Jordana, N'goran Justin Koffi, Pierre Le Bars, Assem Soueidan
The objective of this work is to define the conditions for improving the use of laser Doppler flowmetry (LDF) and to determine the limits for the use of this technique. This article systematically reviews the literature on the evaluation of oral soft tissue blood microcirculation by LDF. We analysed the available literature through October 2016 using the database resources Medline/PubMed, the Cochrane Oral Health Group Specialist Trials Register and the ISI Web of Knowledge. Several points emerged from this literature review The use of LDF involves specific constraints; however, the influence of different factors (temperature, tobacco, pressure etc...
February 2018: Archives of Oral Biology
Daniel P O'Hair, Tanvir K Bajwa, Jeffrey J Popma, Daniel R Watson, Steven J Yakubov, David H Adams, Samin Sharma, Newell Robinson, George Petrossian, Michael Caskey, Timothy Byrne, Neal S Kleiman, Angie Zhang, Michael J Reardon
BACKGROUND: Transcatheter aortic valve replacement (TAVR) using a self-expanding valve has been shown to be superior to an open operation in high-risk patients. Extensive iliofemoral peripheral vascular disease can prohibit femoral access. In these cases, direct aortic (DA) implantation may be a suitable option. METHODS: The current analysis compared outcomes in patients undergoing TAVR with the self-expanding CoreValve prosthesis (Medtronic, Minneapolis, MN) by direct aortic (DA) access vs iliofemoral (IF) access...
February 2018: Annals of Thoracic Surgery
Artur I Milnerowicz, Aleksandra A Milnerowicz, Marcin Protasiewicz, Wiktor Kuliczkowski
BACKGROUND: Effectiveness of vascular closure devices during endovascular procedures requiring a direct puncture of a vascular prosthesis placed in the inguinal region is unknown. PATIENTS AND METHODS: The retrospective analysis included 134 patients with a history of polyethylene terephthalate (PETE) graft implantation in the inguinal region. In 20 (15 %) patients, haemostasis was achieved with manual compression, in 21 (16 %) with the StarClose™, and in 93 (69 %) with the AngioSeal™ device...
November 21, 2017: VASA. Zeitschrift Für Gefässkrankheiten
Andrea Denegri, Fabian Nietlispach, Jan Kottwitz, Gabor Suetsch, Philipp Haager, Hector Rodriguez, Maurizio Taramasso, Slayman Obeid, Francesco Maisano
BACKGROUND: Published procedural and short-term outcome of the Portico valve for Transcatheter Aortic Valve Implantation (TAVI) is limited. We report a single-center patient series assessing procedural and 30-day outcome of this device. METHODS AND RESULTS: Procedural and 30-day follow-up data were prospectively collected from a consecutive series of 73 patients (80.7±6.9years, 45% male, mean STS score: 4.8±3.9) with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI)...
November 10, 2017: International Journal of Cardiology
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