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Ewing sarcoma intraspine

Amit Agarwal, Sangam Kanekar, Krishnamurthy Thamburaj, Kanupriya Vijay
Intraspinal hemorrhage is very rare and intramedullary hemorrhage, also called hematomyelia, is the rarest form of intraspinal hemorrhage, usually related to trauma. Spinal vascular malformations such intradural arteriovenous malformations are the most common cause of atraumatic hematomyelia. Other considerations include warfarin or heparin anticoagulation, bleeding disorders, spinal cord tumors. Radiation-induced hematomyelia of the cord is exceedingly rare with only one case in literature to date. We report the case of an 8 year old girl with Ewing's sarcoma of the thoracic vertebra, under radiation therapy, presenting with hematomyelia...
October 23, 2014: Neurology International
Sandhya Bordia, Sweta Meena, Bijendar Kumar Meena, Vijay Rajak
Ewing's sarcoma/peripheral primitive neuroectodermal tumor is a small, round, and blue cell malignancy that occurs most often in bone and soft tissues of children and young adults. The intraspinal manifestation of the disease is rare, and when present, this is often misdiagnosed with other varieties of primary spinal tumors. Fine-needle aspiration cytology (FNAC) plays important role in the early diagnosis of these cases. We report such a case of Ewing's sarcoma of thoracic spine with extension into the intradural space, which was initially suspected to be a case of metastatic lesion in an 18-year-old boy...
2014: Case Reports in Oncological Medicine
Qing Zhu, Jisheng Zhang, Jianru Xiao
Ewing's sarcoma is the second most common malignant bone tumor in children and adolescents. The 4 cases described in this study were diagnosed with dumbbell-shaped intraspinal and extraspinal Ewing's sarcomas. The incidence of dumbbell-shaped tumors of this type in the spine is 17.5%. These tumors are often misdiagnosed as neurogenic tumors (schwannoma, neurofibromatosis) or giant cell tumors based on imaging. Radiculopathy is more common than spinal cord compression in Ewing's sarcoma. Preoperative biopsy is strongly recommended...
March 2012: Oncology Letters
Saeed Saeedinia, Mohsen Nouri, Meysam Alimohammadi, Hedieh Moradi, Abbas Amirjamshidi
BACKGROUND: Primary spinal primitive neuroectodermal tumors (PNET) and/or spinal extraskeletal Ewing's sarcoma family tumors (ESET) are rare lesions appearing in the spinal extradural space. One hundred forty-one primary spinal PNETs, including 29 intramedullary lesions, have been reported in the literature. Encountering a case of primary epidural EES/peripheral PNET (pPNET) in sacral level, which is the fifth one occurring at this level in the literature, we have tried to conduct a meta-analysis of the reported cases...
2012: Surgical Neurology International
Santhanagopal Srinivasalu, Albert D'Souza
A 15-yr old boy presented with low backache for 4 months associated with weakness of left lower limb. MRI of lumbosacral spine showed a sacral lesion with intraspinal and presacral soft tissue extension with neural compression. A diagnosis of tuberculosis was considered in the view of high prevalence in this part of the world, however biopsy revealed Ewing's sarcoma. Ewing's tumor of sacrum is rare, but should be suspected in low backache in children. Differential diagnosis for a sacral lesion includes tuberculosis, pyogenic osteomyelitis, lymphoma, chordoma, osteosarcoma and Ewing's sarcoma...
2009: Journal of Radiology Case Reports
Sung Wook Choi, Sung Jin Shin, Kwang Woo Nam, Kyu Bum Seo, Gyeong Min Kim
Primary Ewing's sarcoma of the mobile spine is rare, but nevertheless, is the second most common primary malignant bone neoplasm in children. Furthermore, in contrast to long bone involvement, delays may occur because symptoms may not be present until neurological deficits occur. Here, we report a case of an 8-year-old boy with lower back pain and radicular pain on the posterior lower extremities with tingling and progressively reduced sensation in both feet. The patient initially seemed to have muscle sprain but was eventually diagnosed with Ewing's sarcoma of the L5 vertebra with intraspinal extension...
July 2012: Journal of Pediatric Orthopedics. Part B
Yong Yan, Tao Xu, Juxiang Chen, Guohan Hu, Yicheng Lu
Intraspinal Ewing's sarcoma (ES) and primitive neuroectodermal tumors (PNET) are very rare, and the characteristics and prognoses of the disease remain unclear. We present an illustrative patient with an intradural, extramedullary PNET arising within the cervical spinal canal, with clinical and radiological manifestations of leptomeningeal spread, and review the reports of a further 77 patients with intraspinal ES/PNET. Cox regression analyses showed that tumor location (extradural, intradural) (p=0.002, RR=4...
May 2011: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
A C Iplikcioglu, M A Hatiboglu, E Ozek, C Dinc, M Erdal
OBJECTIVE: The open door laminoplasty technique has been previously used to treat cervical spondylotic myelopathy. We adapted this technique for the removal of spinal tumors all along the spinal axis. METHODS: Between January 2002 and January 2003, 17 patients with various intraspinal lesions underwent open door laminoplasty. The thoracal level was involved in 10 cases, the cervical level in 3 patients and the lumbar level in 4. Location of the tumor was intradural-intramedullary in 7, intradural-extramedullary in 6 and extradural in 4 patients...
November 2010: Central European Neurosurgery
Paul Klimo, Patrick J Codd, Holcombe Grier, Liliana C Goumnerova
Sarcomas that arise from within the spinal canal are rare, particularly within the pediatric population. In general, these primary intraspinal sarcomas are highly aggressive, posing unique treatment challenges with respect to surgery and choice of adjuvant therapy. The goal must be to obtain the most complete resection possible to minimize the risk of recurrence and metastasis, while preventing potential neurological deficits that may result from aggressive surgery. Among these primary intraspinal sarcomas are malignant peripheral nerve sheath tumors and members of the Ewing sarcoma family of tumors...
September 2009: Journal of Neurosurgery. Pediatrics
Seok Won Kim, Ho Shin
Ewing's sarcoma usually arises from skeletal bone, but rarely may have an extraskeletal origin. However, Ewing's sarcoma that originates around the spinal column, especially, the intradural extramedullary type is extremely rare. We report a rare case of primary intraspinal extraskeletal Ewing's sarcoma.
March 2009: Journal of Korean Neurosurgical Society
Ulf Liljenqvist, Thomas Lerner, Henry Halm, Horst Buerger, Georg Gosheger, Winfried Winkelmann
En bloc spondylectomy is a technique that enables wide or marginal resection of malignant lesions of the spine. Both all posterior techniques as well as combined approaches are reported. Aim of the present study was to analyse the results of 21 patients with malignant lesions of the spine, all treated with en bloc excision in a combined posteroanterior (n = 19) or all posterior approach (n = 2). Twenty-one consecutive patients, operated between 1997 and 2005, were included into this retrospective study. Thirteen patients had primary malignant lesions, eight patients had solitary metastases, all located in the thoracolumbar spine...
April 2008: European Spine Journal
Xianyuan Song, Jai Choi, Chandrakant Rao, Sagarika Nallu, Anthony D Nicastri
Primary vertebral Ewing sarcoma-primitive neuroectodermal tumor is uncommon. Although epidural extension has been seen in such tumors, cases with massive intraspinal involvement are decidedly rare. Here we present the case of a 4-year-old girl with back pain and difficulty walking. Magnetic resonance imaging showed a mass filling the spinal canal from T(11) to the L(3)/L(4) levels. Vertebral involvement with extension into the paraspinal soft tissue through neural foramina was seen. Histologically, a small-blue-cell tumor with strong membranous CD99 reactivity was noted...
January 2008: Pediatric Neurology
E Perouli, H Chrysikopoulos, A Vlachos, A Koskinas, A Batistatou, K Polyzoidis
We present a case of extraskeletal Ewing sarcoma (ES) in a 32-year-old male patient. The patient reported a painful mass in the thoracic paraspinal area which reached a considerable size in a one-month interval. Sonography and CT showed a heterogeneous, hypoechoic/hypodense soft tissue mass embedded in the dorsal paraspinal musculature. MRI with contrast enhancement showed a solid tumor surrounding areas of necrosis/cystic degeneration. Despite wide contact with the spine and ribs there was no intrathoracic/intraspinal extension or neural foraminal invasion...
November 2006: JBR-BTR: Organe de la Société Royale Belge de Radiologie (SRBR)
R Kumar, K K Prasad, N Krishnani, D K Chhabra
An unusual case of extradural, intraspinal Ewing's sarcoma with significant extraspinal extension is reported. In view of associated constitutional symptoms, suggestive signs, leucocytosis, elevated ESR and operative findings, the initial diagnosis of Pott's spine was entertained. The lesion however turned out to be infected Ewing's sarcoma on histopathology and bacteriological examination.
December 2000: Neurology India
P A Isotalo, C Agbi, B Davidson, A Girard, S Verma, S J Robertson
Primitive neuroectodermal tumors (PNETs) are aggressive neoplasms composed predominantly of undifferentiated cells that show evidence of neural differentiation. Although their classification has been controversial, PNETs are well recognized primary tumors of both central and peripheral nervous systems. PNETs must be distinguished from other round-cell tumors, including Ewing's sarcoma, lymphoma, rhabdomyosarcoma, and small cell carcinoma. Intraspinal PNETs are rare neoplasms that are usually metastatic in origin...
August 2000: Human Pathology
G Dorfmüller, F G Würtz, H W Umschaden, R Kleinert, P F Ambros
Two patients with primary intraspinal primitive neuroectodermal tumour are presented. In a 32-year-old man, the tumour evolved intradurally from a sacral nerve root. Despite repeated surgery and radiochemotherapy, the patient suffered multiple intraspinal tumour relapses and intracranial seedings, and died 29 months after the first diagnosis. In a 17-year-old male adolescent, the tumour was located in the lumbar epidural space, extending into the paraspinal muscles. Following resection and radiochemotherapy, the patient is free from disease 23 months after the initial presentation...
1999: Acta Neurochirurgica
R J Coombs, E A Bayar, Y H Matloub, M E Velasco
No abstract text is available yet for this article.
January 1999: Radiographics: a Review Publication of the Radiological Society of North America, Inc
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