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https://www.readbyqxmd.com/read/28812035/bioabsorbable-versus-metal-screw-in-the-fixation-of-tibial-tubercle-transfer-a-cadaveric-biomechanical-study
#1
Janne T Nurmi, Ari Itälä, Raine Sihvonen, Petri Sillanpää, Pekka Kannus, Harri Sievänen, Teppo L N Järvinen
BACKGROUND: In tibial tubercle transfer (TTT) procedures, the osteotomized and transferred tibial tubercle is usually fixed into the host bone using metal screws. PURPOSE: To compare the strength of fixation provided by a single bioabsorbable screw versus a metal screw for TTT. STUDY DESIGN: Controlled laboratory study. METHODS: Twenty-two pairs of human cadaveric tibiae were used to compare the fixation strength of a single 4...
July 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28811108/methylene-blue-guided-debridement-as-an-intraoperative-adjunct-for-the-surgical-treatment-of-periprosthetic-joint-infection
#2
Jeremy D Shaw, Steve Miller, Anna Plourde, Daniel L Shaw, Rosanna Wustrack, Erik N Hansen
BACKGROUND: Current methods to identify infected tissue in periprosthetic joint infection (PJI) are inadequate. The purpose of this study was (1) to assess methylene blue-guided surgical debridement as a novel technique in PJI using quantitative microbiology and (2) to evaluate clinical success based on eradication of infection and infection-free survival. METHODS: Sixteen total knee arthroplasty patients meeting Musculoskeletal Infection Society criteria for PJI undergoing the first stage of 2-stage exchange arthroplasty were included in this prospective study...
July 21, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28810991/posterior-cruciate-ligament-injuries-associated-with-military-survival-swim-training
#3
Michael S Crowell, John S Mason, Matthew A Posner, Chad A Haley
OBJECTIVES: Posterior cruciate ligament (PCL) injuries are relatively common injuries associated with athletic activities and high-energy trauma. Posterolateral corner (PLC) injuries frequently accompany injury to the PCL. Diagnosis can be challenging and requires a comprehensive history and physical examination. Patients frequently report vague, nonspecific symptoms and the mechanism of injury is often useful in localizing injured structures. Two of the more common mechanisms for PCL injury include a direct blow to the proximal anterior tibia with the knee flexed, as well as a significant knee hyperextension injury...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28810567/factors-related-to-infection-after-fixation-in-the-process-of-late-healed-bone-fracture
#4
Xiaoming Zhang, Xuebin Zhan, Peng Zou, Huixia An
We studied the factors related to infection after fixation in the process of bone late healed fracture and explored the factors that could predict the risk of postoperative infection. A total of 100 patients with open fractures of the tibia and fibula diagnosed in Zhengzhou No. 7 People's Hospital from 2007 to 2016 were enrolled in this study. Patients were subjected to staging surgery treatment. We divided them into the infection group (n=52) and the non-infection group (n=48) according to whether or not infection occurred after operation...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28808631/painless-swollen-calf-muscles-of-a-75-year-old-patient-caused-by-bilateral-venous-malformations
#5
Roderick S M Piekaar, Eline W Zwitser, Paul P A Hedeman Joosten, Joris A Jansen
A 75-year-old man presented with knee pain due to medial osteoarthritis of the knee in the orthopedic outpatient clinic. Conservative treatment was started with steroid infiltration. Besides his knee complaint reported a bilateral painless swollen calf muscle without traumatic cause, and also without any pain at night, fever or medical illness. On physical examination the soleus muscle had a swollen aspect in both calfs. The skin appeared normal without deformities and the arterial pulsations were intact. An X-ray did not show abnormalities in the tibia...
July 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28808627/non-ossifying-fibromas-case-series-including-in-uncommon-upper-extremity-sites
#6
Akio Sakamoto, Ryuzo Arai, Takeshi Okamoto, Shuichi Matsuda
AIM: To investigate non-ossifying fibromas (NOFs) common fibrous bone lesions in children that occur in bones of the lower extremities. METHODS: We analyzed 44 cases of NOF including 47 lesions, which were referred with a working diagnosis of neoplastic lesions. Lesions were located in the upper extremities (1 proximal humerus, 1 distal radius) and the lower extremities (25 distal femurs, 12 proximal and 4 distal tibias, and 4 proximal fibulas). RESULTS: Three cases had NOFs in multiple anatomical locations (femur and fibula in 1 case, femur and tibia in 2 cases)...
July 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28806709/in-vivo-kinematics-of-early-stage-osteoarthritic-knees-during-pivot-and-squat-activities
#7
Keisuke Matsuki, Kei O Matsuki, Tomonori Kenmoku, Satoshi Yamaguchi, Takahisa Sasho, Scott A Banks
Kinematic changes have been shown to accompany severe knee osteoarthritis, but no studies have analyzed early-stage osteoarthritic knee kinematics in the transverse plane during functional activities. The purpose of this study was to analyze kinematics of early-stage osteoarthritic knees using model registration techniques. Fifteen early-stage osteoarthritic knees from eight females with a mean age of 52 years old (range, 43-57years old) were involved in this study. A radiologist confirmed with plain radiographs that knees had Kellgren-Lawrence grade-1 or -2 arthritic changes...
August 4, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28804716/open-wedge-high-tibial-osteotomy-with-distal-tubercle-osteotomy-lessens-change-in-patellar-position
#8
Hoon Park, Hyun Woo Kim, Jin Hwa Kam, Dong Hoon Lee
The purpose of this study was to investigate the change in patellar position after open wedge high tibial osteotomy (OWHTO) with distal tubercle osteotomy (DTO), comparing outcomes of conventional OWHTO in young adults with proximal tibia varus deformity but no arthritic manifestations. Thirty-three patients (mean age, 31.8 years) subjected to OWHTO/DTO were matched with 30 patients (mean age, 33.5 years) undergoing conventional OWHTO. Patellar position, as measured in pre- and postoperative standing lateral radiographs, was compared...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28804540/restoration-of-bone-defects-using-modified-heterogeneous-deproteinized-bone-seeded-with-bone-marrow-mesenchymal-stem-cells
#9
Jun Li, Zeyu Huang, Liyan Chen, Xin Tang, Yue Fang, Lei Liu
The aim of the present study was to investigate the effect of modified heterogeneous deproteinized bone combined with bone marrow mesenchymal stem cells (BMSCs) in the restoration of a validated bone defect model. BMSCs were identified by flow cytometry and multilineage differentiation assay. The structural features of the modified heterogeneous deproteinized bone scaffold and biocompatibility between BMSCs and the scaffold were confirmed by scanning electron microscope (SEM) detection. The cytotoxicity of the modified heterogeneous deproteinized bone scaffolds were detected by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenytetrazolium bromide (MTT) assay...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/28803758/association-between-body-weight-and-proximal-tibial-bone-mineral-density-after-bilateral-total-knee-arthroplasty
#10
Yoshinori Ishii, Hideo Noguchi, Junko Sato, Hana Ishii, Koji Todoroki, Shin-Ichi Toyabe
BACKGROUND: Proximal tibial bone mineral density (BMD) has been studied for its potential impact on subsidence and loosening of the tibial component after total knee arthroplasty (TKA). However, no known studies of proximal tibial BMD after TKA have evaluated the effect of major impact factors such as body weight (BW), muscle strength, and level of activity. We aim to determine whether factors such as level of activity, quadriceps strength, BW, gender, age, and prosthetic design affect proximal tibial BMD over the mid- to long-term following TKA...
August 10, 2017: Knee
https://www.readbyqxmd.com/read/28803236/enhancement-of-bone-healing-by-local-administration-of-carbon-nanotubes-functionalized-with-sodium-hyaluronate-in-rat-tibiae
#11
Vanessa B Andrade, Marcos A Sá, Renato M Mendes, Paulo A Martins-Júnior, Gerluza A B Silva, Bruna R Sousa, Marcelo V Caliari, Erick S Ávila, Luiz Orlando Ladeira, Rodrigo R Resende, Anderson J Ferreira
It has been reported that carbon nanotubes (CNTs) serve as nucleation sites for the deposition of bone matrix and cell proliferation. Here, we evaluated the effects of multi-walled CNTs (MWCNTs) on bone repair of rat tibiae. Furthermore, because sodium hyaluronate (HY) accelerates bone restoration, we associated CNTs with HY (HY-MWCNTs) in an attempt to boost bone repair. The bone defect was created by a 1.6-mm-diameter drill. After 7 and 14 days, tibiae were processed for histological and morphometric analyses...
August 12, 2017: Cells, Tissues, Organs
https://www.readbyqxmd.com/read/28803215/structural-tribological-and-mechanical-properties-of-the-hind-leg-joint-of-a-jumping-insect-using-katydids-to-inform-bioinspired-lubrication-systems
#12
Jun Kyun Oh, Spencer T Behmer, Richelle Marquess, Cengiz Yegin, Ethan A Scholar, Mustafa Akbulut
This study investigates the structural properties of the hind leg femur-tibia joint in adult katydids (Orthoptera: Tettigoniidae), including its tribological and mechanical properties. It is of particular interest because the orthopteran (e.g., grasshoppers, crickets, and katydids) hind leg is highly specialized for jumping. We show that the katydid hind leg femur-tibia joint had unique surfaces and textures, with a friction coefficient (μ) at its coupling surface of 0.053 ± 0.001. Importantly, the sheared surfaces at this joint showed no sign of wear or damage, even though it had undergone thousands of external shearing cycles...
August 9, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28802745/circumferential-bone-grafting-around-an-absorbable-gelatin-sponge-core-reduced-the-amount-of-grafted-bone-in-the-induced-membrane-technique-for-critical-size-defects-of-long-bones
#13
Jae-Woo Cho, Jinil Kim, Won-Tae Cho, Jin-Kak Kim, Jong Hoon Song, Hyung-Jin Kim, Alain C Masquelet, Jong-Keon Oh
OBJECTIVES: The objectives of the study were to introduce a circumferential bone graft around an absorbable gelatin sponge core using an induced membrane technique, to assess its ability to reduce the required amount of graft and to maintain the bone graft, and to evaluate the clinical outcomes in the management of critical-size bone defects. PATIENTS AND METHODS: Circumferential bone grafting using a staged induced membrane technique for managing critical-size bone defects was performed in 21 patients...
August 8, 2017: Injury
https://www.readbyqxmd.com/read/28800714/sagittal-subtalar-and-talocrural-joint-assessment-during-ambulation-with-controlled-ankle-movement-cam-boots
#14
Benjamin D McHenry, Emily L Exten, Janelle A Cross, Karen M Kruger, Brian Law, Jessica M Fritz, Gerald Harris
BACKGROUND: The purpose of the current study was to determine sagittal plane talocrural and subtalar kinematic differences between barefoot and controlled ankle movement (CAM) boot walking. This study used fluoroscopic images to determine talar motion relative to tibia and calcaneal motion relative to talus. METHODS: Fourteen male subjects (mean age 24.1 ± 3.5 years) screened for normal gait were tested. A fluoroscopy unit was used to collect images at 200 Hz during stance...
August 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/28799995/fassier-duval-telescopic-system-how-i-do-it
#15
Francois Fassier
The author describes step-by-step the technique for Fassier-Duval rodding of both femurs and tibiae in osteogenesis imperfecta. Preoperative evaluations and planning, postoperative care and place of bisphosphonates as explained. Emphasis is given on the different tricks to avoid intraoperative problems.
September 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28799855/surgical-management-of-cervical-spine-deformity-in-chondrodysplasia-punctata
#16
Nobuhito Morota, Satoshi Ihara, Hideki Ogiwara, Goichiro Tamura
OBJECTIVE Chondrodysplasia punctata (CDP), a rare skeletal dysplasia, can lead to cervical spine instability and deformity. However, an optimal neurosurgical intervention has yet to be established. Thus, a retrospective study was conducted to assess the efficacy of various surgical interventions for children with CDP. METHODS The authors retrospectively reviewed 9 cases of CDP in which cervical decompression with or without posterior fusion was performed between April 2007 and May 2016. Patient demographics, preoperative clinical conditions, radiographic findings, surgical procedures, and the postoperative course were analyzed in detail...
August 11, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28799237/anticancer-efficacy-of-the-hypoxia-activated-prodrug-evofosfamide-is-enhanced-in-combination-with-proapoptotic-receptor-agonists-against-osteosarcoma
#17
Vasilios Liapis, Aneta Zysk, Mark DeNichilo, Irene Zinonos, Shelley Hay, Vasilios Panagopoulos, Alexandra Shoubridge, Christopher Difelice, Vladimir Ponomarev, Wendy Ingman, Gerald J Atkins, David M Findlay, Andrew C W Zannettino, Andreas Evdokiou
Tumor hypoxia is a major cause of treatment failure for a variety of malignancies. However, hypoxia also leads to treatment opportunities as demonstrated by the development of compounds that target regions of hypoxia within tumors. Evofosfamide is a hypoxia-activated prodrug that is created by linking the hypoxia-seeking 2-nitroimidazole moiety to the cytotoxic bromo-isophosphoramide mustard (Br-IPM). When evofosfamide is delivered to hypoxic regions of tumors, the DNA cross-linking toxin, Br-IPM, is released leading to cell death...
August 10, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28795206/children-and-adolescents-with-cystic-fibrosis-display-moderate-bone-microarchitecture-abnormalities-data-from-high-resolution-peripheral-quantitative-computed-tomography
#18
C Braun, J Bacchetta, P Braillon, R Chapurlat, J Drai, P Reix
We investigated whether bone microstructure assessed by high-resolution peripheral quantitative tomography (HR-pQCT) could be altered in children and teenagers with cystic fibrosis (CF). In comparison to their healthy counterparts, bone microstructure was mildly affected at the tibial level only. INTRODUCTION: Cystic fibrosis-related bone disease (CFBD) may alter bone health, ultimately predisposing patients to bone fractures. Our aim was to assess bone microstructure using high-resolution peripheral quantitative tomography (HR-pQCT) in a cohort of children and teenagers with CF in comparison to age-, puberty-, and gender-matched healthy volunteers (HVs)...
August 9, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28793051/resistance-training-attenuates-salt-overload-induced-cardiac-remodeling-and-diastolic-dysfunction-in-normotensive-rats
#19
D L M Barretti, S F S Melo, E M Oliveira, V G Barauna
Elevated salt intake induces changes in the extracellular matrix collagen, leading to myocardial stiffness and impaired relaxation. Resistance training (RT) has been used as a remarkably successful strategy in the treatment of heart disease. Therefore, the aim of this study was to investigate the effects of RT on preventing pathological adaptation of the left ventricle (LV) induced by salt overload. Male Wistar rats (10 weeks old) were distributed into four groups (n=8/group): control (CO), control+1% salt (CO+SALT), RT and RT+1% salt (RT+SALT)...
August 7, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/28791659/three-dimensional-analysis-of-the-tibial-resection-plane-relative-to-the-arthritic-tibial-plateau-in-total-knee-arthroplasty
#20
J Michael Johnson, Mohamed R Mahfouz, Mehmet Rüştü Midillioğlu, Alexander J Nedopil, Stephen M Howell
BACKGROUND: Kinematically aligned total knee arthroplasty strives to correct the arthritic deformity by restoring the native tibial joint line. However, the precision of such surgical correction needs to be quantified in order to reduce recuts of the resection and to design assisting instrumentation. This study describes a method for novel three-dimensional analysis of tibial resection parameters in total knee arthroplasty. Pre-operative versus post-operative differences in the slopes of the varus-valgus and flexion-extension planes and the proximal-distal level between the tibia resection and the arthritic tibial joint line can reliably be measured using the three-dimensional models of the tibia and fibula...
August 8, 2017: Journal of Experimental Orthopaedics
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