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https://www.readbyqxmd.com/read/28222835/clinical-assessment-of-urinary-tract-damage-during-sustained-release-estrogen-supplementation-in-mice
#1
Dalis E Collins, Kathleen R Mulka, Mark J Hoenerhoff, Russell S Taichman, Jason S Villano
Estrogen supplementation is a key component of numerous mouse research models but can adversely affect the urinary system. The goal of this study was to develop a clinical scoring system and identify biomarkers of occult urinary tract lesions prior to the development of systemic illness in mice. Ovariectomized or sham-surgery SCID mice were implanted subcutaneously with a placebo pellet or one containing sustained-release estradiol (0.18 mg 60-d release 17β-estradiol). Mice were assessed twice weekly for 4 to 6 wk by using a clinical scoring system that included body condition, general activity, posture, hair coat, hydration, abdominal distension, urine staining of coat and skin, and ability to urinate...
February 1, 2017: Comparative Medicine
https://www.readbyqxmd.com/read/28222149/ultrasonographic-evaluation-of-urinary-tract-morbidity-in-school-aged-and-preschool-aged-children-infected-with-schistosoma-haematobium-and-its-evolution-after-praziquantel-treatment-a-randomized-controlled-trial
#2
Beatrice Barda, Jean T Coulibaly, Christoph Hatz, Jennifer Keiser
BACKGROUND: Schistosoma haematobium infections are responsible for significant urinary tract (UT) complications. Schistosomiasis control programs aim to reduce morbidity, yet the extent of morbidity in preschool-aged children and the impact of treatment on morbidity reduction are not well studied. METHODOLOGY: Our study was embedded in a randomized, placebo-controlled, single-blind trial in Côte d'Ivoire, which evaluated the efficacy and safety of three doses (20, 40 and 60 mg/kg) of praziquantel in school-aged (SAC) and preschool-aged (PSAC) children infected with S...
February 21, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28216926/urological-disorders-and-pregnancy-an-overall-experience
#3
Debasmita Mandal, Mriganka Mouli Saha, Dillip Kumar Pal
AIM: Pregnancy is an anatomical and physiological altered state and the presence of various urological problems not only aggravates the disease itself, but also results in unfavourable pregnancy outcome. Aim is to highlight obstetric outcome in pregnant women with urological problems. MATERIALS AND METHODS: Longitudinal prospective cohort study conducted in tertiary care hospital, IPGME and R, Kolkata from Jan 2011 to Dec 2012. All pregnant women with urological problems were included as subjects...
January 2017: Urology Annals
https://www.readbyqxmd.com/read/28215834/time-to-resolution-a-prospective-evaluation-from-the-society-for-fetal-urology-hydronephrosis-registry
#4
R S Zee, C D Anthony Herndon, C S Cooper, C Kim, P H McKenna, A Khoury, K W Herbst
INTRODUCTION: The resolution rate of prenatal urinary tract dilation (UTD) has been documented in several retrospective studies. The present study analyzed prospective observational registry data, with the aim of determining time to resolution among patients prenatally identified with mild postnatal UTD. MATERIALS AND METHODS: A total of 248 subjects, from four centers, were prospectively enrolled from 2008 to 2015. Exclusion criteria included other anomalies (n = 69), fewer than two ultrasounds, and/or <3 months follow-up (n = 26)...
January 19, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28209548/the-iatrogenic-fibroepithelial-polyps-in-children-with-hydronephrosis
#5
Houwei Lin, Maosheng Xu, Dapeng Jiang, Guofeng Xu, Xiaoliang Fang, Lei He, Hongquan Geng
OBJECTIVE: To discover the possible factor of the iatrogenic fibroepithelial polyps. MATERIALS AND METHODS: A retrospective chart review of 28 pediatric patients who have undergone pyeloplasties for ureteropelvic junction obstructio with pathologically proven FEPs was performed from January 2009 to June 2016 at our hospital. Among them, six patients without apparent FEPs at the time of the first pyeloplasty were found to have FEPs at the time of reoperation. The medical history and clinical, diagnostic, intraoperative, pathologic, and follow-up data of the six patients were reviewed...
February 13, 2017: Urology
https://www.readbyqxmd.com/read/28207528/idiopathic-retroperitoneal-fibrosis-causing-unilateral-ureteral-and-sigmoid-colon-obstruction-a-case-report
#6
Ting Yan, Yujuan Wang, Zhijun Liu, Xiaolei Zhang, Qian Wu, Mingrong Xi
OBJECTIVE: The present report aimed to present a unique case of idiopathic retroperitoneal fibrosis (RPF) presenting features of unilateral ureteral and sigmoid colon obstruction. RPF is a rare disorder with unclear etiology. CASE REPORT: A 43-year-old female had a 10-day history of lower right abdominal and lumbar pain. Gynecological examination, ultrasound, and computed tomography (CT) were all suggestive of right ovarian tumor. An enhanced CT showed right-sided hydronephrosis...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28191792/laparoscopic-management-of-recurrent-ureteropelvic-junction-obstruction-following-pyeloplasty-a-single-surgical-team-experience-with-38-cases
#7
Francesco Chiancone, Maurizio Fedelini, Luigi Pucci, Clemente Meccariello, Paolo Fedelini
PURPOSE: To describe and analyze our experience with Anderson-Hynes transperitoneal laparoscopic pyeloplasty (LP) in the treatment of recurrent ureteropelvic junction obstruction (UPJO). MATERIALS AND METHODS: 38 consecutive patients who underwent transperitoneal laparoscopic redo-pyeloplasty between January 2007 and January 2015 at our department were included in the analysis. 36 patients were previously treated with dismembered pyeloplasty and 2 patients underwent a retrograde endopyelotomy...
January 27, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28180090/supernumerary-kidney-associated-with-horseshoe-malformation-a-case-report-and-review-of-literature
#8
Hassan Jamshidian, Kiana Tavakoli, Faeze Salahshour, Amirreza Nabighadim, Erfan Amini
We report a case of supernumerary kidney associated with horseshoe malformation. A 35-year-old man presented complaining of vague and intermittent left flank pain from few months ago. Ultrasonography of urinary tract showed bilateral hydronephrosis and was suggestive of the horseshoe anomaly. Further evaluation with Intravenous urography showed three renal moieties consisting of a horseshoe kidney and a malrotated right kidney cephalad to and fused with the right moiety of horseshoe kidney.
February 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28168568/purtscher-like-retinopathy-associated-with-squamous-cell-carcinoma-of-the-cervix
#9
Darren Shu Jeng Ting, Jonathan Smith, Stephen James Talks
PURPOSE: To describe a previously unreported case of Purtscher-like retinopathy secondary to severe acute renal failure associated with squamous cell carcinoma of the cervix. METHODS: This is a case report. RESULTS: A 31-year-old female presented with a week history of acute abdominal pain, vomiting and severe renal failure followed by a sudden onset of bilateral visual loss. Vision was hand movement in either eye with central scotoma. Ophthalmic examination demonstrated bilateral retinal thickening and whitening with intraretinal hemorrhages localized to the peripapillary area, consistent with the diagnosis of Purtscher-like retinopathy...
February 6, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28168226/does-the-use-of-bedside-ultrasonography-reduce-emergency-department-length-of-stay-for-patients-with-renal-colic-a-pilot-study
#10
Yong Hoon Park, Ru Bi Jung, Young Geun Lee, Chong Kun Hong, Jung-Hwan Ahn, Tae Yong Shin, Young Sik Kim, Young Rock Ha
OBJECTIVE: The aim of this study was to evaluate the effect of adding bedside ultrasonography to the diagnostic algorithm for nephrolithiasis on emergency department (ED) length of stay. METHODS: A prospective, randomized, controlled pilot study was conducted from October 2014 to December 2014 with patients with acute flank pain. In the non-ultrasonography group (NUSG), non-contrast computed tomography was selected based on clinical features and hematuria in the urinalysis...
December 2016: Clinical and Experimental Emergency Medicine
https://www.readbyqxmd.com/read/28166087/genitourinary-malformations-an-under-recognized-feature-of-ectrodactyly-ectodermal-dysplasia-and-cleft-lip-palate-syndrome
#11
Zerin Hyder, Victoria Beale, Ruth O'Connor, Jill Clayton-Smith
The ectodermal dysplasia and cleft lip/palate (EEC) syndrome describes the association of ectrodactyly, ectodermal dysplasia and orofacial clefting. As with many autosomal dominant disorders, there is variability in expression and not all of these three core features are present in every individual with the condition. Moreover, there may be additional associated features, which are under-recognized. One of these is the presence of genitourinary anomalies, some of which cause significant morbidity. This report details a further two patients with EEC syndrome and genitourinary involvement, including flaccid megacystis with detrusor muscle failure, bilateral hydronephrosis and megaureter, requiring significant renal and urological involvement during their childhood...
February 3, 2017: Clinical Dysmorphology
https://www.readbyqxmd.com/read/28166076/bedside-ultrasound-in-the-emergency-department-to-detect-hydronephrosis-for-the-evaluation-of-suspected-ureteric-colic
#12
R Shrestha, R M Shakya, A Khan A
Background Renal colic is a common emergency department presentation. Hydronephrosis is indirect sign of urinary obstruction which may be due to obstructing ureteric calculus and can be detected easily by bedside ultrasound with minimal training. Objective To compare the accuracy of detection of hydronephrosis performed by the emergency physician with that of radiologist's in suspected renal colic cases. Method This was a prospective observational study performed over a period of 6 months. Patients >8 years with provisional diagnosis of renal colic with both the bedside ultrasound and the formal ultrasound performed were included...
April 2016: Kathmandu University Medical Journal (KUMJ)
https://www.readbyqxmd.com/read/28161315/renal-development-in-the-fetus-and-premature-infant
#13
REVIEW
Stacy Rosenblum, Abhijeet Pal, Kimberly Reidy
Congenital abnormalities of the kidney and urinary tract (CAKUT) are one of the leading congenital defects to be identified on prenatal ultrasound. CAKUT represent a broad spectrum of abnormalities, from transient hydronephrosis to severe bilateral renal agenesis. CAKUT are a major contributor to chronic and end stage kidney disease (CKD/ESKD) in children. Prenatal imaging is useful to identify CAKUT, but will not detect all defects. Both genetic abnormalities and the fetal environment contribute to CAKUT. Monogenic gene mutations identified in human CAKUT have advanced our understanding of molecular mechanisms of renal development...
February 1, 2017: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28153776/robot-assisted-laparoscopic-pyeloureterostomy-in-infants-with-duplex-systems-and-upper-pole-hydronephrosis-variations-in-double-j-ureteral-stenting-techniques
#14
Minki Baek, Jason Au, Gene O Huang, Chester J Koh
OBJECTIVE: We describe our experience with robot-assisted laparoscopic (RAL) pyeloureterostomy in infants with duplex systems and upper pole hydronephrosis with an emphasis on the various double J (DJ) ureteral stent placement techniques. METHODS: We used our RAL pyeloureterostomy technique in two female infants with duplex systems and upper pole hydronephrosis. For case 1, we introduced the DJ stent and placed it in the recipient lower pole ureter during the robotic operation in an antegrade fashion...
January 19, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28149933/utility-of-clinical-risk-stratification-in-the-selection-of-muscle-invasive-bladder-cancer-patients-for-neoadjuvant-chemotherapy-a-retrospective-cohort-study
#15
Friedrich-Carl von Rundstedt, Douglas A Mata, Oleksandr N Kryvenko, Anup A Shah, Iny Jhun, Seth P Lerner
Introduction: Level I evidence supports the use of cisplatin-based neoadjuvant chemotherapy (NAC) for muscle-invasive bladder cancer prior to radical cystectomy (RC). On average, 30-40% of patients achieve a complete pathologic response (i.e., stage pT0) after receiving NAC. Some centers risk-stratify patients, suggesting that there may be a higher-risk population that would derive the most benefit from NAC. Recently, a risk-stratification model developed at M.D. Anderson Cancer Center (MDACC) specified criteria for clinical staging and patient selection for NAC...
January 27, 2017: Bladder Cancer
https://www.readbyqxmd.com/read/28146287/vesicopreputial-anastomosis-for-the-treatment-of-obstructive-urolithiasis-in-goats
#16
Elizabeth Erin Cypher, Sarel R van Amstel, Ricardo Videla, Kyle Force Clark, David E Anderson
OBJECTIVE: To describe a novel surgical technique for the correction of recurrent obstructive urolithiasis in male goats. STUDY DESIGN: Clinical case series. ANIMALS: Castrated male goats (n = 4). METHODS: Medical records of male goats having undergone vesicopreputial anastomosis (VPA) as a treatment for obstructive urolithiasis were reviewed for history, signalment, clinical signs, and intraoperative and postoperative complications...
February 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28145916/hydronephrosis-presenting-6-months-after-sacral-colpopexy-case-report-and-literature-review
#17
Emily Weber LeBrun, Estefania Santamaria, Louis Moy
OBJECTIVES: The aim of this study was to describe a case of uterovaginal prolapse managed with robotic-assisted sacral colpopexy complicated by severe right-sided hydronephrosis despite normal intraoperative cystoscopy. METHODS: A 68-year-old woman presented with a worsening vaginal bulge over the past 2 years. Tricompartment stage 2 uterovaginal prolapse, with dominant cystocele and skin erosion at the posterior fourchette from prolapse friction, was identified on physical examination, and the patient underwent pelvic reconstructive surgery, including sacral colpopexy...
January 31, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28138408/kidney-ultrasound-what-is-important-for-a-urologist
#18
REVIEW
Tomasz Szopiński, Elżbieta Keller, František Záťura
Kidney ultrasound is one of the basic procedures in the practice of a urologist. Apart from the location and the size, description of renal morphology should contain the thickness of the anterior lip parenchyma in a transverse section and the location of possible narrowings. Uneven outline of the kidney is a sign of past inflammatory conditions. In the case of the pelvicalyceal system dilation, it is advised to specify the dimensions of the pelvis and calyces. Convex shape of the calyces proves elevated pressure within the pelvicalyceal system...
December 2016: Journal of Ultrasonography
https://www.readbyqxmd.com/read/28133847/fetal-megacystis-prediction-of-spontaneous-resolution-and-outcome
#19
F Fontanella, L Duin, P N Adama van Scheltema, T E Cohen-Overbeek, E Pajkrt, M Bekker, C Willekes, C J Bax, C M Bilardo
OBJECTIVES: To predict likelihood of spontaneous resolution during fetal life and postnatal outcome of fetal megacystis, diagnosed in all trimesters in pregnancy. METHODS: This was a national retrospective cohort study. Fetal megacystis was defined in the first trimester as a longitudinal bladder diameter (LBD) ≥ 7 mm, and in the 2(nd) and 3(rd) trimester as an enlarged bladder failing to empty during the entire extended ultrasound (US) examination. LBD and GA at resolution were investigated as of likelihood of resolution and of postnatal outcome, respectively...
January 30, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28133307/-a-case-of-familial-adenomatous-polyposis-with-a-desmoid-tumor-probably-communicating-to-the-intestinal-lumen-that-was-successfully-treated-with-non-surgical-therapy
#20
Tetsuya Ito, Noriyasu Chika, Azusa Yamamoto, Toshiro Ogura, Kunihiko Amano, Toru Ishiguro, Minoru Fukuchi, Youichi Kumagai, Keiichiro Ishibashi, Hidetaka Eguchi, Yasushi Okazaki, Erito Mochiki, Hideyuki Ishida
A 44-year-old man with familial adenomatous polyposis underwent laparoscopic-assistedtotal proctocolectomy with ilealpouch anal anastomosis(IPAA). Computed tomography conducted 21 months after IPAA demonstrated bilateral hydronephrosis andan intra-abdominal mass with a maximal diameter of 22 cm, leading to a diagnosis of stage IV desmoid disease, according to the classification by Church and associates. Six courses of combination chemotherapy with doxorubicin plus dacarbazine were administered. Computed tomography after chemotherapy demonstrated marked shrinkage of the desmoidtumor with intraabdominal air andfluidcollection extending just below the skin of the ileostomy closure site...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
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