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Malnutrition in HIV

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https://www.readbyqxmd.com/read/28187062/risk-factors-for-growth-retardation-in-hiv-infected-senegalese-children-on-antiretroviral-treatment-the-anrs-12279-maggsen-pediatric-cohort-study
#1
Cecile Cames, Lea Pascal, Aminata Diack, Helene Mbodj, Baly Ouattara, Ndeye Rama Diagne, Ndeye Fatou Diallo, Philippe Msellati, Ngagne Mbaye, Haby Sy Signate
OBJECTIVES: We described prevalence and risk factors for wasting and stunting among HIV-infected children with a median duration of 3 years of antiretroviral therapy (ART) at the time of their enrollment in the cohort study. METHODS: Wasting and stunting at ART initiation and at enrollment were defined as weight-for-height/body mass index-for-age z-scores < -2 and height-for-age z-scores < -2, respectively. Logistic regression was used to assess risk factors for wasting and stunting...
December 13, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28166247/recovery-rate-and-associated-factors-of-children-age-6-to-59-months-admitted-with-severe-acute-malnutrition-at-inpatient-unit-of-bahir-dar-felege-hiwot-referral-hospital-therapeutic-feeding-unite-northwest-ethiopia
#2
Hanna Demelash Desyibelew, Abel Fekadu, Haile Woldie
BACKGROUND: Despite numerous advances made in improving child health and the clinical management protocols for treating severe acute malnutrition at treatment centers, evidences concerning the treatment outcomes are scarce. Therefore, this study was conducted to assess the recovery rate and associated factors of severely acute malnourished children of age 6 to 59 months admitted to inpatient therapeutic feeding unit at Felege Hiwot Referral Hospital. METHODS: We conducted a hospital-based cross-sectional study including 401 severely malnourished children who were admitted from September 2012 to January 2016...
2017: PloS One
https://www.readbyqxmd.com/read/28164028/the-clinical-spectrum-of-severe-acute-malnutrition-in-children-in-cameroon-a-hospital-based-study-in-yaounde-cameroon
#3
Andreas Chiabi, Berthe Malangue, Seraphin Nguefack, Félicitée Nguefack Dongmo, Florence Fru, Virginie Takou, Fru Angwafo
BACKGROUND: Severe acute malnutrition (SAM) is a major health problem, and the cause of more than half of childhood deaths in children less than 5 years in developing countries. Globally, 20 million children under 5 years of age are severely malnourished according to the World Health Organization (WHO). In Cameroon, the prevalence of SAM remains high and estimated at 1.9% in 2011 and 1.3% in 2014. The aim of this study was to determine the epidemiology, clinical aspects and outcome of SAM at the Yaounde Gynaeco-Obstetric and Pediatric Hospital (YGOPH)...
January 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28150466/who-will-be-lost-identifying-patients-at-risk-of-loss-to-follow-up-in-malawi-the-dream-program-experience
#4
S Mancinelli, K Nielsen-Saines, P Germano, G Guidotti, E Buonomo, P Scarcella, R Lunghi, H Sangare, S Orlando, G Liotta, M C Marazzi, L Palombi
OBJECTIVES: Retention of subjects in HIV treatment programmes is crucial for the success of treatment. We evaluated retention/loss to follow-up (LTFU) in subjects receiving established care in Malawi. METHODS: Data for HIV-positive patients registered in Drug Resource Enhancement Against AIDS and Malnutrition centres in Malawi prior to 2014 were reviewed. Visits entailing HIV testing/counselling, laboratory evaluations, nutritional evaluation/supplementation, community support, peer education, and antiretroviral (ART) monitoring/pharmacy were noted...
February 2, 2017: HIV Medicine
https://www.readbyqxmd.com/read/28149793/our-experience-with-smartphone-and-spherical-lens-for-the-eye-fundus-examination-during-humanitarian-project-in-africa
#5
Alena Furdova, Adriana Furdova, Vladimir Krcmery
To present the experience of eye fundus photo documentation by using the plus 20 diopters spherical Volk lens and a smartphone with 4.2 Mpix camera and LED flash within the screening project of eye disorders in countries where the standard ophthalmology equipment is not available. Totally 241 patients underwent ophthalmology screening examination. The documentation of the eye fundus included patients with Burkitt lymphoma, Kala Azar, malnutrition with unknown etiology, tuberculosis, HIV positive patients, Usher syndrome and hypertension...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28110145/virusseeker-a-computational-pipeline-for-virus-discovery-and-virome-composition-analysis
#6
Guoyan Zhao, Guang Wu, Efrem S Lim, Lindsay Droit, Siddharth Krishnamurthy, Dan H Barouch, Herbert W Virgin, David Wang
The advent of Next Generation Sequencing (NGS) has vastly increased our ability to discover novel viruses and to systematically define the spectrum of viruses present in a given specimen. Such studies have led to the discovery of novel viral pathogens as well as broader associations of the virome with diverse diseases including inflammatory bowel disease, severe acute malnutrition and HIV/AIDS. Critical to the success of these efforts are robust bioinformatic pipelines for rapid classification of microbial sequences...
January 18, 2017: Virology
https://www.readbyqxmd.com/read/28093536/noma-overview-of-a-neglected-disease-and-human-rights-violation
#7
M Leila Srour, Klaas Marck, Denise Baratti-Mayer
Noma is an orofacial gangrene affecting malnourished children and mainly observed in tropical countries, particularly sub-Saharan Africa. Epidemiological data on noma are scarce, but a current estimate of the global incidence is 30,000-40,000 cases per year, with a mortality rate of approximately 85% and a burden of disease calculated to be a loss of 1-10 million disability-adjusted life years. The etiology of noma is multifactorial with malnutrition as an ever present factor, often in combination with concomitant diseases, such as measles, malaria, and human immunodeficiency virus (HIV), and poor oral hygiene...
February 8, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28056035/a-systematic-review-of-the-incidence-risk-factors-and-case-fatality-rates-of-invasive-nontyphoidal-salmonella-ints-disease-in-africa-1966-to-2014
#8
Ifeanyi Valentine Uche, Calman A MacLennan, Allan Saul
This study systematically reviews the literature on the occurrence, incidence and case fatality rate (CFR) of invasive nontyphoidal Salmonella (iNTS) disease in Africa from 1966 to 2014. Data on the burden of iNTS disease in Africa are sparse and generally have not been aggregated, making it difficult to describe the epidemiology that is needed to inform the development and implementation of effective prevention and control policies. This study involved a comprehensive search of PubMed and Embase databases...
January 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28031190/risk-factors-for-death-in-children-during-inpatient-treatment-of-severe-acute-malnutrition-a-prospective-cohort-study
#9
Maren Jh Rytter, Esther Babirekere-Iriso, Hanifa Namusoke, Vibeke B Christensen, Kim F Michaelsen, Christian Ritz, Charlotte G Mortensen, Ezekiel Mupere, Henrik Friis
BACKGROUND: Children who receive in-hospital treatment of severe acute malnutrition often have high mortality rates, and the reasons are not well understood. OBJECTIVE: We assessed risk factors for death in children who were treated for malnutrition in a hospital. DESIGN: In a prospective observational study of 120 children who were receiving in-hospital treatment of severe acute malnutrition in Uganda with therapeutic formulas F-75 and F-100, we collected data on symptoms, clinical findings, plasma markers of refeeding syndrome (electrolytes and phosphate), and acute phase reactants, and recorded the nutritional therapy given in hospital...
December 28, 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28030608/predicting-hospitalised-paediatric-pneumonia-mortality-risk-an-external-validation-of-risc-and-mrisc-and-local-tool-development-risc-malawi-from-malawi
#10
Shubhada Hooli, Tim Colbourn, Norman Lufesi, Anthony Costello, Bejoy Nambiar, Satid Thammasitboon, Charles Makwenda, Charles Mwansambo, Eric D McCollum, Carina King
BACKGROUND: Pneumonia is the leading infectious cause of under-5 mortality in sub-Saharan Africa. Clinical prediction tools may aide case classification, triage, and allocation of hospital resources. We performed an external validation of two published prediction tools and compared this to a locally developed tool to identify children admitted with pneumonia at increased risk for in-hospital mortality in Malawi. METHODS: We retrospectively analyzed the performance of the Respiratory Index of Severity in Children (RISC) and modified RISC (mRISC) scores in a child pneumonia dataset prospectively collected during routine care at seven hospitals in Malawi between 2011-2014...
2016: PloS One
https://www.readbyqxmd.com/read/27998310/pre-art-nutritional-status-and-its-association-with-mortality-in-adult-patients-enrolled-on-art-at-fiche-hospital-in-north-shoa-oromia-region-ethiopia-a-retrospective-cohort-study
#11
Kokeb Tesfamariam, Negga Baraki, Haji Kedir
BACKGROUND: Human immunodeficiency virus (HIV) compromises the nutritional status of infected individuals and in turn, malnutrition worsens the effects of the infection itself by weakening the immune system consequently accelerating disease progression and death. However, few studies have examined the association between nutritional status at antiretroviral therapy (ART) initiation and early mortality. Therefore, this study assesses pre-ART nutritional status and other baseline characteristics and mortality among adult patients on ART at Fiche Hospital, Ethiopia...
December 20, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27960210/community-acquired-pneumonia-in-latin-america
#12
Hernán A Iannella, Carlos M Luna
Community-acquired pneumonia (CAP) is associated with significant morbidity and mortality in Latin America and the Caribbean (LAC) region. Poverty, socioeconomic factors, and malnutrition influence the incidence and outcome of CAP in LAC. In LAC, Streptococcus pneumoniae is the most frequent microorganism responsible for CAP, (incidence: 24-78%); the incidence of atypical microorganisms is similar to other regions of the world. Human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) is a growing problem in the LAC region, with the Caribbean being the second most affected area worldwide after Sub-Saharan Africa...
December 2016: Seminars in Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27924741/health-and-health-related-indicators-in-slum-rural-and-urban-communities-a-comparative-analysis
#13
Blessing U Mberu, Tilahun Nigatu Haregu, Catherine Kyobutungi, Alex C Ezeh
BACKGROUND: It is generally assumed that urban slum residents have worse health status when compared with other urban populations, but better health status than their rural counterparts. This belief/assumption is often because of their physical proximity and assumed better access to health care services in urban areas. However, a few recent studies have cast doubt on this belief. Whether slum dwellers are better off, similar to, or worse off as compared with rural and other urban populations remain poorly understood as indicators for slum dwellers are generally hidden in urban averages...
2016: Global Health Action
https://www.readbyqxmd.com/read/27906025/nutritional-status-and-its-effect-on-treatment-outcome-among-hiv-infected-clients-receiving-haart-in-ethiopia-a-cohort-study
#14
Sadikalmahdi Hussen, Tefera Belachew, Nezif Hussien
PURPOSES: The aim of this study was to determine the effects of nutritional status at the start of highly active anti-retroviral therapy on treatment outcomes among HIV/AIDS patients taking HAART at Jimma University Specialized Hospital. METHODS: We performed a retrospective cohort study involving 340 adults who started highly active anti-retroviral therapy. The patients have been clinically followed for 2 years. Data were extracted from paper based medical charts by trained data collectors from January 30 to February 28, 2014 using data collection format...
September 22, 2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27905971/trends-causes-and-risk-factors-of-mortality-among-children-under-5-in-ethiopia-1990-2013-findings-from-the-global-burden-of-disease-study-2013
#15
Amare Deribew, Gizachew Assefa Tessema, Kebede Deribe, Yohannes Adama Melaku, Yihunie Lakew, Azmeraw T Amare, Semaw F Abera, Mesoud Mohammed, Abiy Hiruye, Efrem Teklay, Awoke Misganaw, Nicholas Kassebaum
BACKGROUND: Ethiopia has made remarkable progress in reducing child mortality over the last two decades. However, the under-5 mortality rate in Ethiopia is still higher than the under-5 mortality rates of several low- and middle-income countries (LMIC). On the other hand, the patterns and causes of child mortality have not been well investigated in Ethiopia. The objective of this study was to investigate the mortality trend, causes of death, and risk factors among children under 5 in Ethiopia during 1990-2013...
November 14, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27891065/trends-causes-and-risk-factors-of-mortality-among-children-under-5-in-ethiopia-1990-2013-findings-from-the-global-burden-of-disease-study-2013
#16
Amare Deribew, Gizachew Assefa Tessema, Kebede Deribe, Yohannes Adama Melaku, Yihunie Lakew, Azmeraw T Amare, Semaw F Abera, Mesoud Mohammed, Abiy Hiruye, Efrem Teklay, Awoke Misganaw, Nicholas Kassebaum
BACKGROUND: Ethiopia has made remarkable progress in reducing child mortality over the last two decades. However, the under-5 mortality rate in Ethiopia is still higher than the under-5 mortality rates of several low- and middle-income countries (LMIC). On the other hand, the patterns and causes of child mortality have not been well investigated in Ethiopia. The objective of this study was to investigate the mortality trend, causes of death, and risk factors among children under 5 in Ethiopia during 1990-2013...
2016: Population Health Metrics
https://www.readbyqxmd.com/read/27881690/acceptability-of-outpatient-ready-to-use-food-based-protocols-in-hiv-infected-senegalese-children-and-adolescents-within-the-maggsen-cohort-study
#17
Cecile Cames, Marie Varloteaux, Ndeye Ngone Have, Alhadji Bassine Diom, Philippe Msellati, Ngagne Mbaye, Helene Mbodj, Haby Sy Signate, Aminata Diack
OBJECTIVES: To assess the acceptability of ready-to-use food (RUF)-based outpatient protocols in HIV-infected children and adolescents with severe acute malnutrition (SAM) and moderate acute malnutrition (MAM). METHODS: Plumpy Nut and Plumpy Sup were supplied every 2 weeks and prescribed by weight to SAM and MAM children, respectively. Forty-three children, 24 MAM and 19 SAM, were enrolled. Organoleptic appreciation, feeding modalities, and perceptions surrounding RUF were recorded at week 2...
November 22, 2016: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/27843745/bibliometric-analysis-of-medicine-related-publications-on-poverty-2005-2015
#18
Waleed M Sweileh, Samah W Al-Jabi, Ansam F Sawalha, Adham S AbuTaha, Sa'ed H Zyoud
BACKGROUND: Poverty is a global problem. The war against poverty requires not only financial support, but also poverty-related research to pinpoint areas of high need of intervention. In line with international efforts to fight poverty and negative consequences, we carried out this study to give a bibliometric overview of medicine-related literature on poverty. Such a s study is an indicator of the extent of interaction of various international key players on the war against poverty-related health problems...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27829445/improving-early-childhood-care-and-development-hiv-testing-treatment-and-support-and-nutrition-in-mokhotlong-lesotho-study-protocol-for-a-cluster-randomized-controlled-trial
#19
Mark Tomlinson, Sarah Skeen, Marguerite Marlow, Lucie Cluver, Peter Cooper, Lynne Murray, Shoeshoe Mofokeng, Nathene Morley, Moroesi Makhetha, Sarah Gordon, Tonya Esterhuizen, Lorraine Sherr
BACKGROUND: Since 1990, the lives of 48 million children under the age of 5 years have been saved because of increased investments in reducing child mortality. However, despite these unprecedented gains, 250 million children younger than 5 years in low- and middle-income countries (LMIC) cannot meet their developmental potential due to poverty, poor health and nutrition, and lack of necessary stimulation and care. Lesotho has high levels of poverty, HIV, and malnutrition, all of which affect child development outcomes...
November 9, 2016: Trials
https://www.readbyqxmd.com/read/27825956/psychosocial-factors-influencing-preferences-for-food-and-nutritional-supplements-among-people-living-with-hiv-in-bangkok-thailand
#20
Santiago Rodas-Moya, Supabhorn Pengnonyang, Stephen Kodish, Saskia de Pee, Praphan Phanuphak
Malnutrition and HIV are often coincident and may lead to wasting, a strong predictor of mortality. However; ready to use therapeutic foods (RUTF) are showing promising results in restoring the nutritional status of adult people living with HIV (PLHIV) in resource constrained settings but, its acceptability seems low. This study aimed to identify the psychosocial factors influencing general preferences for food and responses to five potential nutritional supplements to guide the development of novel products to treat malnutrition among PLHIV...
January 1, 2017: Appetite
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