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https://www.readbyqxmd.com/read/29468802/synergistic-effect-of-strontium-bioactive-glass-and-nano-hydroxyapatite-promotes-bone-regeneration-of-critical-sized-radial-bone-defects
#1
Ahmad Oryan, Mohamadreza Baghaban Eslaminejad, Amir Kamali, Samaneh Hosseini, Forough Azam Sayahpour, Hossein Baharvand
Critical-sized bone defects constitute a major health issue in orthopedics and usually cause mal-unions due to an inadequate number of migrated progenitor cells into the defect site or their incomplete differentiation into osteogenic precursor cells. The current study aimed to develop an optimized osteoinductive and angiogenic scaffold by incorporation of strontium (Sr) and bioglass (BG) into gelatin/nano-hydroxyapatite (G/nHAp) seeded with bone marrow mesenchymal stem cells to enhance bone regeneration. The scaffolds were fabricated by a freeze-drying technique and characterized in terms of morphology, structure, porosity and degradation rate...
February 21, 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29457246/randomized-controlled-prospective-clinical-trial-of-autologous-greater-omentum-free-graft-versus-autogenous-cancellous-bone-graft-in-radial-and-ulnar-fractures-in-miniature-breed-dogs
#2
Jennifer J Ree, Wendy I Baltzer, Sarah Nemanic
OBJECTIVE: To determine the rate of radiographic healing, complications, vascularization, and bone density after repair of radial and ulnar fractures in dogs <6 kg that were treated with an autogenous cancellous bone graft (BG) or free autologous omentum graft (OG). STUDY DESIGN: Prospective, randomized, controlled clinical trial with owners/radiologists blinded to treatment. ANIMALS: 25 dogs with naturally occurring traumatic radial/ulnar fractures...
February 19, 2018: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/29432893/improvement-of-cognitive-functions-in-response-to-a-regular-nordic-walking-training-in-elderly-women-a-change-dependent-on-the-training-experience
#3
A Gmiąt, J Jaworska, K Micielska, J Kortas, K Prusik, K Prusik, M Lipowski, A Radulska, N Szupryczyńska, J Antosiewicz, E Ziemann
Although regular physical activity is known to benefit health of aging populations, there are still many factors, which regulate exercise-induced adaptive changes. Among many vitamin D and myokines are under consideration. We, therefore, evaluated the influence of a single session of and regular Nordic Walking (NW) training combined with vitamin D supplementation on cognitive functions and muscle strength and some elements of the amino-acid profile. Thirty-five healthy elderly women (68 ± 5 years old) from health promotion programmes took part in the study...
February 9, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29430266/minimally-invasive-sacroiliac-joint-fusion-2-year-radiographic-and-clinical-outcomes-with-a-principles-based-sij-fusion-system
#4
William W Cross, Arnold Delbridge, Donald Hales, Louis C Fielding
Background: Sacroiliac joint (SIJ) degeneration is a common source of low back pain (LBP). Minimally invasive (MI) SIJ fusion procedures have demonstrated meaningful clinical improvement. A recently developed MI SIJ fusion system incorporates decortication, placement of bone graft and fixation with threaded implants (DC/BG/TF). Patients and Methods: Nineteen patients who had MI SIJ fusion with DC/BG/TF were enrolled at three centers. Fusion was assessed in CT images obtained 12 and 24 months postoperatively by an independent radiographic core laboratory...
2018: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/29427529/efficient-bioconversion-of-oleuropein-from-olive-leaf-extract-to-antioxidant-hydroxytyrosol-by-enzymatic-hydrolysis-and-high-temperature-degradation
#5
Min Liu, Qiang Yong, Shiyuan Yu
Hydroxytyrosol (HT), a powerful antioxidant, clears free radicals and exhibits many biological activities. Because contents of HT are low in natural sources, bioconversion of oleuropein (OLE) to HT is of increasing interest. A biotechnological process was investigated to produce HT from OLE presented in olive leaf extract. Enzymatic hydrolysis using two cellulases with high BG activity, Novozymes CTec2 and commercial cellulase KDN (Qingdao, China), was carried out at 50 °C for 12 h followed by raising the temperature to 90 °C for chemical hydrolysis...
February 10, 2018: Biotechnology and Applied Biochemistry
https://www.readbyqxmd.com/read/29425471/antidiabetic-effect-of-rosella-stevia-tea-on-prediabetic-women-in-yogyakarta-indonesia
#6
Noor Rohmah Mayasari, Susetyowati, Mae Sri Hartati Wahyuningsih, Probosuseno
BACKGROUND: Rosella tea (Hibiscuss sabdariffa. Linn) with stevia sweetener (Stevia rebaudiana Bertoni) is a combined herbal drink that is expected to have antidiabetic effect by lowering glucose levels in people with diabetes and prediabetes. This research investigates the effect of rosella-stevia tea to decrease fasting blood glucose (FBG) and 2 hours postprandial blood glucose (2-hour postprandial BG) level in prediabetic women. METHOD: This is quasi-experimental research with control and treatment (rosella-stevia tea) group...
February 9, 2018: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/29421420/continuous-blood-glucose-monitoring-may-detect-carotid-occlusion-intolerance-during-carotid-artery-stenting
#7
Ryo Hiramatsu, Motomasa Furuse, Ryokichi Yagi, Tomohisa Ohmura, Hiroyuki Ohnishi, Naokado Ikeda, Naosuke Nonoguchi, Shinji Kawabata, Shigeru Miyachi, Toshihiko Kuroiwa
BACKGROUND: The frequency of the occurrence of adverse events associated with carotid artery stenting (CAS) is usually low, but serious adverse events such as cerebral hyperperfusion syndrome (CHS) may occur. Real-time monitoring is ideal for the early detection of adverse events during the surgical procedure. This study aimed to evaluate continuous blood glucose (BG) monitoring for the detection of adverse events during CAS. METHODS: Forty patients undergoing scheduled CAS were prospectively enrolled...
February 5, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29409264/a-comparison-of-the-all-inside-arthroscopic-brostr%C3%A3-m-procedure-with-the-traditional-open-modified-brostr%C3%A3-m-gould-technique-a-review-of-62-patients
#8
Ryan B Rigby, James M Cottom
BACKGROUND: The open Broström-Gould lateral ankle stabilization procedure has been the gold standard for primary lateral ankle stabilization. A new minimally invasive all-inside arthroscopic technique has been described for the correction of lateral ankle instability. METHODS: We performed a review of patients who underwent lateral ankle stabilization by either the traditional open Broström-Gould (BG) or the All-Inside Bröstrom (AIB) technique to compare and identify any discrepancies between functional and/or patient satisfaction outcomes...
February 5, 2018: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29381253/accuracy-and-precision-of-flash-glucose-monitoring-sensors-inserted-into-the-abdomen-and-upper-thigh-compared-to-the-upper-arm-out-of-sight
#9
Sara Charleer, Chantal Mathieu, Frank Nobels, Pieter Gillard
Nowadays, most Belgian patients with type 1 diabetes use flash glucose monitoring (FreeStyle® Libre™ [FSL]) to check their glucose values, but some patients find the sensor on the upper arm too visible. The aim of this study was to compare accuracy and precision of FSL sensors when placed on different sites. Twenty-three adults with type 1 diabetes used three FSL sensors simultaneously for 14 days on upper arm, abdomen, and upper thigh. FSL measurements were compared to capillary blood glucose (BG) measurements obtained with built-in FSL BG meter...
January 30, 2018: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/29375025/comparison-of-nostocean-hormogonium-induction-and-its-motility-on-solid-plates-between-agar-and-gellan-gum-at-varying-gel-matrix-concentrations
#10
Hiroaki Nishizuka, Yasuyuki Hashidoko
To establish a sensitive bioassay for Nostocean hormogonium induction, we compared the effectiveness of the morpho-differentiation induction on two gelled plates, agar and gellan gum, for anacardic acid C15:1-Δ8 decyl ester (1) (100 nmol/disc). On BG-110 (nitrogen-free) medium-based 0.6 and 0.8% agar plates, Nostoc sp. strain Yaku-1 isolated from a coralloid root of Cycas revoluta in Yakushima Island showed clear morpho-differentiation from filamentous aggregates into hormogonia, and the induced hormogonia dispersed within 24 h; however, similar hormogonium formation was not observed at agar concentrations of 1...
January 29, 2018: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/29317385/development-and-evaluation-of-a-mobile-personalized-blood-glucose-prediction-system-for-patients-with-gestational-diabetes-mellitus
#11
Evgenii Pustozerov, Polina Popova, Aleksandra Tkachuk, Yana Bolotko, Zafar Yuldashev, Elena Grineva
BACKGROUND: Personalized blood glucose (BG) prediction for diabetes patients is an important goal that is pursued by many researchers worldwide. Despite many proposals, only a few projects are dedicated to the development of complete recommender system infrastructures that incorporate BG prediction algorithms for diabetes patients. The development and implementation of such a system aided by mobile technology is of particular interest to patients with gestational diabetes mellitus (GDM), especially considering the significant importance of quickly achieving adequate BG control for these patients in a short period (ie, during pregnancy) and a typically higher acceptance rate for mobile health (mHealth) solutions for short- to midterm usage...
January 9, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29313296/the-biological-effects-of-the-hypolipidaemic-drug-probucol-microcapsules-fed-daily-for-4%C3%A2-weeks-to-an-insulin-resistant-mouse-model-potential-hypoglycaemic-and-anti-inflammatory-effects
#12
Armin Mooranian, Rebecca Negrulj, Ryu Takechi, John Mamo, Hesham Al-Sallami, Hani Al-Salami
Probucol (PB) is an hypolipidaemic drug with potential antidiabetic effects. We showed recently using in vitro studies that when PB was incorporated with stabilising lipophilic bile acids and microencapsulated using the polymer sodium alginate, the microcapsules showed good stability but poor and irregular PB release. This suggests that PB microcapsules may exhibit better release profile and hence better absorption, if more hydrophilic bile acids were used, such as ursodeoxycholic acid (UDCA). Accordingly, this study aimed to produce PB-UDCA microcapsules and examine PB absorption and antidiabetic effects in our mouse-model of insulin-resistance and diabetes (fed high-fat diet; HFD)...
January 8, 2018: Drug Delivery and Translational Research
https://www.readbyqxmd.com/read/29303609/buffering-agent-induced-lactose-content-increases-via-growth-hormone-mediated-activation-of-gluconeogenesis-in-lactating-goats
#13
L Li, M L He, Y Liu, Y S Zhang
Dairy goats are often fed a high-concentrate (HC) diet to meet their lactation demands; however, long-term concentrate feeding is unhealthy and leads to milk yield and lactose content decreases. Therefore, we tested whether a buffering agent is able to increase the output of glucose in the liver and influence lactose synthesis. Eight lactating goats were randomly assigned to two groups: one group received a HC diet (Concentrate : Forage = 6:4, HG) and the other group received the same diet with a buffering agent added (0...
January 5, 2018: Physiological Research
https://www.readbyqxmd.com/read/29285031/efficacy-of-modified-bioactive-glass-for-dentin-remineralization-and-obstruction-of-dentinal-tubules
#14
Mahshid Saffarpour, Maryam Mohammadi, Mohammadreza Tahriri, Azadeh Zakerzadeh
Objectives: This study assessed the efficacy of modified bioactive glass (MBG) for dentin remineralization and obstruction of dentinal tubules. Materials and Methods: Thirty-six dentin discs were made from 20 third molars and were stored in 12% lactic acid solution for two weeks to induce demineralization. The samples were divided into three groups (n=12): 1- BG, 2- BG modified with 5% strontium (Sr) and 3- BG modified with 10% Sr. After applying the BG, the samples were stored in artificial saliva for 7, 14 and 21 days...
July 2017: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/29284522/dengue-and-yellow-fever-virus-vectors-seasonal-abundance-diversity-and-resting-preferences-in-three-kenyan-cities
#15
Sheila B Agha, David P Tchouassi, Armanda D S Bastos, Rosemary Sang
BACKGROUND: The transmission patterns of dengue (DENV) and yellow fever (YFV) viruses, especially in urban settings, are influenced by Aedes (Stegomyia) mosquito abundance and behavior. Despite recurrent dengue outbreaks on the Kenyan coast, these parameters remain poorly defined in this and other areas of contrasting dengue endemicity in Kenya. In assessing the transmission risk of DENV/YFV in three Kenyan cities, we determined adult abundance and resting habits of potential Aedes (Stegomyia) vectors in Kilifi (dengue-outbreak prone), and Nairobi and Kisumu (no dengue outbreaks reported)...
December 29, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29273446/stress-hyperglycemia-in-general-surgery-why-should-we-care
#16
Georgia Davis, Maya Fayfman, David Reyes-Umpierrez, Shahzeena Hafeez, Francisco J Pasquel, Priyathama Vellanki, J Sonya Haw, Limin Peng, Sol Jacobs, Guillermo E Umpierrez
AIMS: To determine the frequency of increasing levels of stress hyperglycemia and its associated complications in surgery patients without a history of diabetes. METHODS: We reviewed hospital outcomes in 1971 general surgery patients with documented preoperative normoglycemia [blood glucose (BG) <140mg/dL] who developed stress hyperglycemia (BG >140mg/dL or >180mg/dL) within 48h after surgery between 1/1/2010 and 10/31/2015. RESULTS: A total of 415 patients (21%) had ≥1 episode of BG between 140 and 180mg/dL and 206 patients (10...
November 29, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/29251061/use-of-decision-support-software-to-titrate-multiple-daily-injections-yielded-sustained-a1c-reductions-after-1-year
#17
Bruce Bode, John G Clarke, Joseph Johnson
PURPOSE: The purpose was to improve the quality of care of at-risk patients through the addition of connected BG meters and CDSS to improve workflow and thus provide more efficient titration of patient's insulin regimens remotely between office visits in an attempt to treat them to their glucose targets faster and efficiently, and maintain that improvement over time. METHODS: Hardware and software included a real-time cellular-enabled blood glucose (BG) meter and Glytec's Glucommander™ clinical decision support software (CDSS)...
December 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29243582/consensus-validation-of-simpler%C3%A2-a-tool-to-improve-pharmacist-delivery-of-quality-evidence-based-diabetes-care
#18
Shamala Ayadurai, V Bruce Sunderland, Lisa Bg Tee, H Laetitia Hattingh
BACKGROUND: Studies on a structured method used by pharmacists to provide comprehensive, evidence-based diabetes care are lacking. The aim of this study was to prioritise, rank and construct validate indicators categorised as seven treatment factors utilised in the management of diabetes namely: cholesterol, blood pressure and glycaemia control; medication and lifestyle management; cardiovascular risk strategies and education using the Delphi process. METHODS: A Delphi questionnaire consisted of 29 Part 1 and nine Part 2 indicators which were incorporated into a tool called Simpler™...
December 14, 2017: Current Diabetes Reviews
https://www.readbyqxmd.com/read/29227292/association-of-hyperglycemia-systolic-and-diastolic-hypertension-and-hyperthermia-relative-to-baseline-in-the-acute-phase-of-stroke-with-poor-outcome-after-intravenous-thrombolysis
#19
Stefano Forlivesi, Nicola Micheletti, Giampaolo Tomelleri, Paolo Bovi, Manuel Cappellari
: In the acute phase of ischemic stroke, the trend of some physiological variables, such as blood glucose (BG), blood pressure, and body temperature (BT), might influence outcome. We aimed to assess the association of hyperglycemia, systolic and diastolic hypertension, and hyperthermia relative to baseline BG, systolic blood pressure, diastolic blood pressure and BT, respectively, in the first 12 h with poor outcome after intravenous thrombolysis (IVT). We conducted a retrospective analysis of data prospectively collected from 200 consecutive anterior ischemic stroke patients treated with IVT...
December 8, 2017: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/29222837/low-melt-bioactive-glass-reinforced-3d-printing-akermanite-porous-cages-with-highly-improved-mechanical-properties-for-lumbar-spinal-fusion
#20
Xiurong Ke, Lei Zhang, Xianyan Yang, Juncheng Wang, Chen Zhuang, Zhouwen Jin, An Liu, Tengfei Zhao, Sanzhong Xu, Changyou Gao, Zhongru Gou, Guojing Yang
Although great strides have been made in medical technology, low back/neck pain and intervertebral disc degeneration initiated from disc degenerative disease remains a clinical challenge. Within the field of regenerative medicine therapy, we have sought to improve the biomechanical transformation of spinal fusion procedures conducted using biodegradable porous implants. Specifically, we have focused on developing mechanically strong bioceramic cages for spinal fusion and functional recovery. Herein we fabricated the akermanite (AKE) ceramic-based porous cages using low-melting bioactive glass (BG) and 3D printing technology...
December 9, 2017: Journal of Tissue Engineering and Regenerative Medicine
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