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https://www.readbyqxmd.com/read/28493444/impact-of-hyperlipidaemia-on-intermediary-metabolism-faecal-microbial-metabolites-and-urinary-characteristics-of-lipoprotein-lipase-deficient-vs-normal-cats
#1
N Paßlack, J Zentek, J A Larsen, J L Westropp, A J Fascetti
Findings in humans and rats indicate that hyperlipidaemia may be associated with enhanced endogenous oxalate (Ox) synthesis, which may be relevant for calcium oxalate (CaOx) urolith formation. Moreover, changes in lipid metabolism are proposed to negatively affect gut microbiota. This study aimed to investigate those potential interactions in hyperlipidaemic cats. Therefore, 10 normal control cats and seven lipoprotein lipase (LPL)-deficient cats were fed a low-fat diet for seven weeks. During the last week of the study, cats were housed in metabolic cages to collect urine and faeces...
May 11, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28463428/single-layer-cystotomy-closure-of-excised-porcine-bladders-with-barbed-versus-smooth-suture-material
#2
Joshua S Montel, Daniel J Duffy, Hsin-Yi Weng, Lynetta J Freeman
OBJECTIVE: To determine which of 2 suture materials would be superior in terms of closure time and leakage pressure in open single-layer cystotomy closure. STUDY DESIGN: Experimental study. ANIMALS: Twenty-four freshly harvested porcine urinary bladders. METHODS: A cystotomy was performed and the incision closed with a single layer simple continuous suture pattern with barbed (n = 12) or smooth (n = 12) suture...
May 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28444749/transurethral-removal-of-a-cystic-urolith-in-a-mare-using-a-laparoscopic-specimen-pouch
#3
A J Williamson, A O McKinnon
CASE REPORT: Cystic urolithiasis is the most common form of urolithiasis reported in horses. In contrast to the gelding or stallion, clinical disease is less common in the mare and manual removal techniques are possible because of their shorter, wider urethral anatomy. However, these manual removal techniques can be traumatic and are limited by the size of the urolith. This report describes the use of a commercial laparoscopic specimen pouch to remove a cystic urolith in a mare. CONCLUSION: This approach may allow the extraction of larger uroliths per urethra in the mare, while affording some protection to the mucosa of the bladder neck and urethra...
May 2017: Australian Veterinary Journal
https://www.readbyqxmd.com/read/28384169/serum-concentrations-of-symmetric-dimethylarginine-and-creatinine-in-cats-with-kidney-stones
#4
Jean A Hall, Maha Yerramilli, Edward Obare, Jun Li, Murthy Yerramilli, Dennis E Jewell
Serum concentrations of symmetric dimethylarginine (SDMA) correlate with renal function in cats and SDMA has been shown to be a more reliable and earlier marker for chronic kidney disease (CKD) compared with serum creatinine (Cr). Calcium oxalate uroliths tend to develop in mid-to-older aged cats and kidney stones may cause a reduction in renal function with increased SDMA, but normal serum Cr. The purpose of this retrospective study was to determine if cats with kidney stones had increased serum SDMA concentrations, and whether SDMA increased earlier than serum creatinine concentrations...
2017: PloS One
https://www.readbyqxmd.com/read/28380506/dietary-cation-anion-difference-may-explain-why-ammonium-urate-nephrolithiasis-occurs-more-frequently-in-common-bottlenose-dolphins-under-human-care-than-in-free-ranging-common-bottlenose-dolphins
#5
A J Ardente, R S Wells, C R Smith, M T Walsh, E D Jensen, T L Schmitt, J Colee, B J Vagt, R C Hill
Ammonium urate nephrolithiasis frequently develops in common bottlenose dolphins () managed under human care but is rare in free-ranging common bottlenose dolphins. In other species, the dietary cation-anion difference (DCAD) can affect ammonium urate urolith formation by increasing proton excretion as ammonium ions. Therefore, differences in diet between the 2 dolphin populations could affect urolith formation, but the DCAD of most species consumed by free-ranging and managed dolphins is unknown. To compare the nutrient composition of diets consumed by free-ranging and managed bottlenose dolphins, samples ( = 5) of the 8 species of fish commonly consumed by free-ranging bottlenose dolphins in Sarasota Bay, FL, and the 7 species of fish and squid commonly fed to managed bottlenose dolphins were analyzed for nutrient content...
March 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28361470/pathogenesis-of-calcium-oxalate-urinary-stone-disease-species-comparison-of-humans-dogs-and-cats
#6
REVIEW
Allison L O'Kell, David C Grant, Saeed R Khan
Idiopathic calcium oxalate nephrolithiasis is a highly recurrent disease that is increasing in prevalence. Decades of research have not identified effective methods to consistently prevent the formation of nephroliths or induce medical dissolution. Idiopathic calcium oxalate nephroliths form in association with renal papillary subepithelial calcium phosphate deposits called Randall's plaques (RPs). Rodent models are commonly used to experimentally induce calcium oxalate crystal and stone formation, but a rodent model that conclusively forms RPs has not been identified...
March 30, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28306489/evaluation-for-association-between-urolithiasis-and-chronic-kidney-disease-in-cats
#7
Andréanne Cléroux, Kate Alexander, Guy Beauchamp, Marilyn Dunn
OBJECTIVE To determine whether urolithiasis is associated with chronic kidney disease (CKD) in cats. DESIGN Retrospective case-control study. ANIMALS 126 cats (59 and 67 with and without urolithiasis, respectively). PROCEDURES Medical records from June 2006 to July 2013 were searched to identify cats that underwent abdominal or focal urinary tract ultrasonography and for which serum creatinine concentration and urine specific gravity data were obtained ≤ 14 days before or after the examination. In cats with (urolithiasis group) and without (control group) urolithiasis, the presence of CKD was determined according to International Renal Interest Society guidelines...
April 1, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28247720/-the-influence-of-alternating-magnetic-field-on-in-vitro-litholysis-of-uroliths-in-blemaren-water-solutions
#8
V M Popkov, D A Usanov, V G Rebrov, A D Usanov, D G Verkhov, V M Bulanov
THE AIM OF THE RESEARCH: increase of efficiency of urolith in vitro solution using water Blemaren medication solutions after their exposure to 2 Hz alternating magnetic field. MATERIALS AND METHODS: water solution of Blemaren medication with pH=6,15 in concentrations corresponding to single portion of medication (1 tablet m=3,5282 g per 250 ml of water) and uroliths (oxalates, urates including uncommon xanthine calculi). Composition of calculi was determined by means of X-ray tests and IR spectroscopy...
August 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28207316/calcium-sulfate-dihydrate-urolithiasis-in-a-pet-rabbit
#9
Jaroslav Kucera, Tamara Koristkova, Barbora Gottwaldova, Vladimir Jekl
CASE DESCRIPTION A 3-year-old sexually intact male rabbit (Oryctolagus cuniculus) was evaluated because of a 1-day history of signs of anorexia and depression. CLINICAL FINDINGS Clinical examination revealed signs of depression, hunched posture, low skin elasticity (suggesting dehydration), slightly distended abdomen, and penile and preputial edema. The owner reported that the rabbit had been fed a routine diet, received water via a sipper bottle, and was allowed free movement around the home. It had been observed by the owner to bite and chew gypsum-based plaster from the walls of the home...
March 1, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28139077/systematic-review-and-meta-analysis-of-the-diagnostic-accuracy-of-low-dose-computed-tomography-of-the-kidneys-ureters-and-bladder-for-urolithiasis
#10
REVIEW
Hao Xiang, Michael Chan, Victoria Brown, Ya Ruth Huo, Lewis Chan, Lloyd Ridley
Renal colic is a common clinical condition which is often investigated with a CT of the kidneys, ureters and bladder (CTKUB). Recent technological improvements have allowed a reduction in dose with the emergence of low-dose CTKUB (LD-CTKUB) techniques. The present meta-analysis aims to determine the diagnostic accuracy of LD-CTKUB in the diagnosis of clinically significant uroliths. A systematic review was performed using nine electronic databases from their dates of inception to May 2016. Inclusion criteria included studies reporting comparative outcomes using LD-CTKUB with a dose less than 3 millisieverts compared to an imaging gold standard or clinical and surgical evaluation...
January 31, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/28042154/analysis-of-canine-urolith-submissions-to-the-canadian-veterinary-urolith-centre-1998-2014
#11
Doreen M Houston, Heather E Weese, Nick P Vanstone, Andrew E P Moore, J Scott Weese
Understanding urolith trends and risk factors is important for understanding urolithiasis, which is a common problem in dogs. This study evaluated 75 674 canine cystolith submissions to the Canadian Veterinary Urolith Centre between 1998 and 2014. Struvite and calcium oxalate uroliths comprised 80.8% of all uroliths, with calcium oxalate outnumbering struvite. There were significant increases in the proportions of calcium oxalate, mixed and cystine uroliths, and significant decreases in struvite, urate, silica, and calcium phosphate carbonate over the study period...
January 2017: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
https://www.readbyqxmd.com/read/27919260/a-frameshift-mutation-in-mocos-is-associated-with-familial-renal-syndrome-xanthinuria-in-tyrolean-grey-cattle
#12
Leonardo Murgiano, Vidhya Jagannathan, Christian Piffer, Inmaculada Diez-Prieto, Marilena Bolcato, Arcangelo Gentile, Cord Drögemüller
BACKGROUND: Renal syndromes are occasionally reported in domestic animals. Two identical twin Tyrolean Grey calves exhibited weight loss, skeletal abnormalities and delayed development associated with kidney abnormalities and formation of uroliths. These signs resembled inherited renal tubular dysplasia found in Japanese Black cattle which is associated with mutations in the claudin 16 gene. Despite demonstrating striking phenotypic similarities, no obvious presence of pathogenic variants of this candidate gene were found...
December 5, 2016: BMC Veterinary Research
https://www.readbyqxmd.com/read/27904786/a-targeted-metabolomics-assay-to-measure-eight-purines-in-the-diet-of-common-bottlenose-dolphins-tursiops-truncatus
#13
A J Ardente, T J Garrett, R S Wells, M Walsh, C R Smith, J Colee, R C Hill
Bottlenose dolphins managed under human care, human beings and Dalmatian dogs are prone to forming urate uroliths. Limiting dietary purine intake limits urate urolith formation in people and dogs because purines are metabolized to uric acid, which is excreted in urine. Managed dolphins develop ammonium urate nephroliths, whereas free-ranging dolphins do not. Free-ranging dolphins consume live fish, whereas managed dolphins consume different species that have been stored frozen and thawed. Differences in the purine content of fish consumed by dolphins under human care versus in the wild may be responsible for the difference in urolith prevalence...
October 2016: Journal of Chromatography & Separation Techniques
https://www.readbyqxmd.com/read/27875079/comparison-of-body-condition-score-and-urinalysis-variables-between-dogs-with-and-without-calcium-oxalate-uroliths
#14
Stephanie M Kennedy, Jody P Lulich, Michelle G Ritt, Eva Furrow
OBJECTIVE To compare body condition score (BCS) and urinalysis variables between dogs with and without calcium oxalate (CaOx) uroliths. DESIGN Case-control study. ANIMALS 46 Miniature Schnauzers, 16 Bichons Frises, and 6 Shih Tzus. PROCEDURES Medical records were reviewed for Miniature Schnauzers, Bichons Frises, and Shih Tzus that were examined between January 2001 and November 2014 for another urolithiasis study or for a urolith removal procedure. Dogs with CaOx uroliths were classified as cases. Dogs without a history of urinary tract disease and with no evidence of radiopaque uroliths on abdominal radiographs were classified as controls...
December 1, 2016: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/27707684/-uroliths-of-cats-in-switzerland-from-2002-to-2009
#15
B Gerber, F Brandenberger-Schenk, E Rothenanger, C Müller
In this study data on composition of uroliths collected from cats and epidemiologic data of affected cats in Switzerland from 2002 to 2009 are summarised. Of 884 stones analysed 50% (n=441) were composed of calcium oxalate, 45% (n=398) of struvite, 3% (n=18) of ammonium urate, 1% (n=12) were mixed stones, 1% (n=9) were composed of silica, 3 stones were solidified blood, 2 consisted of cystine and 1of xanthine. 40% of the ureteral stones were composed of struvite. Domestic cats had significantly less calcium oxalate stones compared to British Shorthair or Persian cats...
October 2016: Schweizer Archiv Für Tierheilkunde
https://www.readbyqxmd.com/read/27611724/acvim-small-animal-consensus-recommendations-on-the-treatment-and-prevention-of-uroliths-in-dogs-and-cats
#16
J P Lulich, A C Berent, L G Adams, J L Westropp, J W Bartges, C A Osborne
In an age of advancing endoscopic and lithotripsy technologies, the management of urolithiasis poses a unique opportunity to advance compassionate veterinary care, not only for patients with urolithiasis but for those with other urinary diseases as well. The following are consensus-derived, research and experience-supported, patient-centered recommendations for the treatment and prevention of uroliths in dogs and cats utilizing contemporary strategies. Ultimately, we hope that these recommendations will serve as a foundation for ongoing and future clinical research and inspiration for innovative problem solving...
September 2016: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/27562981/feline-calcium-oxalate-urolithiasis-risk-factors-and-rational-treatment-approaches
#17
REVIEW
Joseph W Bartges
PRACTICAL RELEVANCE: Uroliths occur commonly in the bladder and/or urethra of cats and can be lifethreatening if urethral obstruction occurs. Calcium oxalate accounts for 40-50% of urocystoliths and these stones are not amenable to medical dissolution; therefore, removal by surgery or minimally invasive techniques is required if uroliths must be treated. Medical protocols for prevention involve decreasing urine saturation for minerals that form uroliths. ETIOPATHOGENESIS: Formation of uroliths is not a disease, but rather a complication of several disorders...
September 2016: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/27540515/cystolithiasis-in-a-syrian-hamster-a-different-outcome
#18
D Petrini, M Di Giuseppe, G Deli, C De Caro Carella
A 14-month-old intact male Syrian hamster was admitted for lethargy and hematuria. A total body radiographic image and abdominal ultrasonography showed the presence of a vesical calculus. During cystotomy, a sterile urine sample was obtained and sent to the diagnostic laboratory along with the urolith for analysis. Urine culture was found negative for bacterial growth, and the urolith was identified as a calcium-oxalate stone. Diet supplementation with palmitoylethanolamide, glucosamine and hesperidin was adopted the day after discharge...
2016: Open veterinary journal
https://www.readbyqxmd.com/read/27404572/cystinuria-associated-with-different-slc7a9-gene-variants-in-the-cat
#19
Keijiro Mizukami, Karthik Raj, Carl Osborne, Urs Giger
Cystinuria is a classical inborn error of metabolism characterized by a selective proximal renal tubular defect affecting cystine, ornithine, lysine, and arginine (COLA) reabsorption, which can lead to uroliths and urinary obstruction. In humans, dogs and mice, cystinuria is caused by variants in one of two genes, SLC3A1 and SLC7A9, which encode the rBAT and bo,+AT subunits of the bo,+ basic amino acid transporter system, respectively. In this study, exons and flanking regions of the SLC3A1 and SLC7A9 genes were sequenced from genomic DNA of cats (Felis catus) with COLAuria and cystine calculi...
2016: PloS One
https://www.readbyqxmd.com/read/27388977/genetic-evaluation-of-english-bulldogs-with-cystine-uroliths
#20
B Ruggerone, S P Marelli, P Scarpa, M Polli
No abstract text is available yet for this article.
August 13, 2016: Veterinary Record
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