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https://www.readbyqxmd.com/read/29245170/-consequences-of-a-failed-project-introduction-and-management-of-a-hospitalization-substituting-treatment-model
#1
Uwe Peters
This article is a report on a psychiatric project introducing services that substitute in-patient treatment and a new control and management system. The implementation of the project was a failure. Nevertheless, the project has made a contribution to further development of community-based psychiatry. Design, organization and course of the project are described and analyzed from the point of view of the communal actors involved. Effects going beyond the time course of the project have been taken into consideration...
December 15, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/29245168/-school-entrance-examination-for-lateral-entrants-what-can-and-what-should-they-be-able-to-do-a-discussion-contribution-based-on-the-data-from-the-health-authority-frankfurt-am-main-2006-2016
#2
Maria Karathana, Bernhard Krackhardt, Manuela Schade, Ursel Heudorf
Question The medical investigation of school beginners is one of the essential tasks of the child and youth services of the health authorities. While in all federal states in Germany, the examination of all school beginners is legally clearly stipulated, the situation for "lateral entry", that is, children of school age, who are moving from a foreign country to a local German community and attending school there, is not clearly regulated in the respective school laws. This article presents the experiences of the lateral entry investigations in Frankfurt am Main...
December 15, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/29245135/acidogenic-fermentation-of-iron-enhanced-primary-sedimentation-sludge-under-different-ph-conditions-for-production-of-volatile-fatty-acids
#3
Lin Lin, Xiao-Yan Li
Iron-based chemically enhanced primary sedimentation (CEPS) is increasingly adopted for wastewater treatment in mega cities, producing a large amount of sludge (Fe-sludge) with a high content of organics for potential organic resource recovery. In this experimental study, acidogenic fermentation was applied treat FeCl3-based CEPS sludge for production of volatile fatty acids (VFAs) at different pHs. Batch fermentation tests on the Fe-sludge with an organic content of 10 g-COD/L showed that the maximum VFAs production reached 2782...
December 6, 2017: Chemosphere
https://www.readbyqxmd.com/read/29245111/community-based-rehabilitation-offers-cost-effective-epilepsy-treatment-in-rural-guinea-bissau
#4
Eric van Diessen, Frank van der Maas, Vladimir Cabral, Willem M Otte
Treatment of epilepsy in low-income countries is a challenge considering the lack of resources, availability of antiepileptic drugs, and cultural beliefs. We used a community-based rehabilitation (CBR) service for the detection, monitoring, and treatment of epilepsy. A local network of trained community volunteers provided education, good quality antiepileptic drugs, and clinical follow-up for people with epilepsy (PWE). In a period of 2years, approximately 22,500 people were screened in central Guinea-Bissau, and 112 PWE were identified and registered...
December 12, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29245043/participation-and-needs-of-children-with-developmental-coordination-disorder-at-home-and-in-the-community-perceptions-of-children-and-parents
#5
Emmanuelle Jasmin, Sylvie Tétreault, Nadine Larivière, Jacques Joly
BACKGROUND: The existing literature provides only a partial understanding of the viewpoints of elementary school-aged children with developmental coordination disorder (DCD) regarding their participation and needs. In order to plan and develop health and social services driven by a personalized approach, it is essential to further document their perceptions with those of their parents. AIMS: The aim of the study was to explore the participation and needs of school-aged children with DCD at home and in the community, as perceived by children and parents...
December 12, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29245042/is-the-diagnostic-threshold-for-bulimia-nervosa-clinically-meaningful
#6
Danielle A N Chapa, Brittany K Bohrer, Kelsie T Forbush
The DSM-5 differentiates full- and sub-threshold bulimia nervosa (BN) according to average weekly frequencies of binge eating and inappropriate compensatory behaviors. This study was the first to evaluate the modified frequency criterion for BN published in the DSM-5. The purpose of this study was to test whether community-recruited adults (N=125; 83.2% women) with current full-threshold (n=77) or sub-threshold BN (n=48) differed in comorbid psychopathology and eating disorder (ED) illness duration, symptom severity, and clinical impairment...
December 8, 2017: Eating Behaviors
https://www.readbyqxmd.com/read/29245022/cost-effective-way-to-reduce-stimulant-abuse-among-gay-bisexual-men-and-transgender-women-a-randomized-clinical-trial-with-a-cost-comparison
#7
S X Zhang, S Shoptaw, C J Reback, K Yadav, A M Nyamathi
OBJECTIVES: A randomized controlled study was conducted with 422 homeless, stimulant-using gay/bisexual (G/B) men and 29 transgender women (n = 451) to assess two community-based interventions to reduce substance abuse and improve health: (a) a nurse case-managed program combined with contingency management (NCM + CM) versus (b) standard education plus contingency management (SE + CM). STUDY DESIGN: Hypotheses tested included: a) completion of hepatitis A/B vaccination series; b) reduction in stimulant use; and c) reduction in number of sexual partners...
December 12, 2017: Public Health
https://www.readbyqxmd.com/read/29244898/climate-driven-diversity-change-in-annual-grasslands-drought-plus-deluge-does-not-equal-normal
#8
Susan P Harrison, Marina L LaForgia, Andrew M Latimer
Climate forecasts agree that increased variability and extremes will tend to reduce the availability of water in many terrestrial ecosystems. Increasingly severe droughts may be exacerbated both by warmer temperatures and by the relative unavailability of water that arrives in more sporadic and intense rainfall events. Using long-term data and an experimental water manipulation, we examined the resilience of a heterogeneous annual grassland community to a prolonged series of dry winters that led to a decline in plant species richness (2000-2014), followed by a near-record wet winter (2016-2017), a climatic sequence that broadly resembles the predicted future in its high variability...
December 15, 2017: Global Change Biology
https://www.readbyqxmd.com/read/29244845/diet-and-stable-isotope-analyses-reveal-the-feeding-ecology-of-the-orangeback-squid-sthenoteuthis-pteropus-steenstrup-1855-mollusca-ommastrephidae-in-the-eastern-tropical-atlantic
#9
Véronique Merten, Bernd Christiansen, Jamileh Javidpour, Uwe Piatkowski, Oscar Puebla, Rebeca Gasca, Henk-Jan T Hoving
In the eastern tropical Atlantic, the orangeback flying squid Sthenoteuthis pteropus (Steenstrup 1855) (Cephalopoda, Ommastrephidae) is a dominant species of the epipelagic nekton community. This carnivore squid has a short lifespan and is one of the fastest-growing squids. In this study, we characterise the role of S. pteropus in the pelagic food web of the eastern tropical Atlantic by investigating its diet and the dynamics of its feeding habits throughout its ontogeny and migration. During three expeditions in the eastern tropical Atlantic in 2015, 129 specimens were caught by hand jigging...
2017: PloS One
https://www.readbyqxmd.com/read/29244837/frailty-and-quality-of-life-among-older-people-with-and-without-a-cancer-diagnosis-findings-from-topics-mds
#10
Noralie Geessink, Yvonne Schoon, Harry van Goor, Marcel Olde Rikkert, René Melis
BACKGROUND: The number of older cancer patients is rising. Especially in older people, treatment considerations should balance the impact of disease and treatment on quality of life (QOL) and survival. How a cancer diagnosis in older people interacts with concomitant frailty to impact on QOL is largely unknown. We aimed to determine the association between frailty and QOL among community-dwelling older people aged 65 years or above with and without a cancer diagnosis cross-sectionally and at 12 months follow-up...
2017: PloS One
https://www.readbyqxmd.com/read/29244829/cost-effectiveness-analysis-of-introducing-malaria-diagnostic-testing-in-drug-shops-a-cluster-randomised-trial-in-uganda
#11
Kristian Schultz Hansen, Siân E Clarke, Sham Lal, Pascal Magnussen, Anthony K Mbonye
BACKGROUND: Private sector drug shops are an important source of malaria treatment in Africa, yet diagnosis without parasitological testing is common among these providers. Accurate rapid diagnostic tests for malaria (mRDTs) require limited training and present an opportunity to increase access to correct diagnosis. The present study was a cost-effectiveness analysis of the introduction of mRDTs in Ugandan drug shops. METHODS: Drug shop vendors were trained to perform and sell subsidised mRDTs and artemisinin-based combination therapies (ACTs) in the intervention arm while vendors offered ACTs following presumptive diagnosis of malaria in the control arm...
2017: PloS One
https://www.readbyqxmd.com/read/29244775/spatial-temporal-and-dietary-variables-associated-with-elevated-mercury-exposure-in-peruvian-riverine-communities-upstream-and-downstream-of-artisanal-and-small-scale-gold-mining
#12
Lauren Wyatt, Ernesto J Ortiz, Beth Feingold, Axel Berky, Sarah Diringer, Ana Maria Morales, Elvis Rojas Jurado, Heileen Hsu-Kim, William Pan
Artisanal and small-scale gold mining (ASGM) is a primary contributor to global mercury and its rapid expansion raises concern for human exposure. Non-occupational exposure risks are presumed to be strongly tied to environmental contamination; however, the relationship between environmental and human mercury exposure, how exposure has changed over time, and risk factors beyond fish consumption are not well understood in ASGM settings. In Peruvian riverine communities (n = 12), where ASGM has increased 4-6 fold over the past decade, we provide a large-scale assessment of the connection between environmental and human mercury exposure by comparing total mercury contents in human hair (2-cm segment, n = 231) to locally caught fish tissue, analyzing temporal exposure in women of child bearing age (WCBA, 15-49 years, n = 46) over one year, and evaluating general mercury exposure risks including fish and non-fish dietary items through household surveys and linear mixed models...
December 15, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29244732/middleware-for-plug-and-play-integration-of-heterogeneous-sensor-resources-into-the-sensor-web
#13
Enoc Martínez, Daniel M Toma, Simon Jirka, Joaquín Del Río
The study of global phenomena requires the combination of a considerable amount of data coming from different sources, acquired by different observation platforms and managed by institutions working in different scientific fields. Merging this data to provide extensive and complete data sets to monitor the long-term, global changes of our oceans is a major challenge. The data acquisition and data archival procedures usually vary significantly depending on the acquisition platform. This lack of standardization ultimately leads to information silos, preventing the data to be effectively shared across different scientific communities...
December 15, 2017: Sensors
https://www.readbyqxmd.com/read/29244703/the-risk-of-assuming-abuse-in-an-infant-with-an-isolated-metaphyseal-lesion-a-case-report
#14
Kirsten Norrell, William Hennrikus
CASE: The classic metaphyseal lesion, or corner fracture, is considered a strong indicator of nonaccidental trauma. In the present case, the parents brought their 8-month-old boy to a community hospital after he stopped crawling on the right leg. A knee radiograph demonstrated an isolated metaphyseal lesion, which prompted concern for child abuse. The patient was transferred to the nearest academic medical center; the pediatric radiology expert in child abuse determined that the lesion was a normal variant and not the result of abuse...
July 2017: JBJS Case Connector
https://www.readbyqxmd.com/read/29244490/discovery-of-potent-and-selective-allosteric-inhibitors-of-protein-arginine-methyltransferase-3-prmt3
#15
H Ümit Kaniskan, Mohammad S Eram, Kehao Zhao, Magdalena M Szewczyk, Xiaobao Yang, Keith Schmidt, Xiao Luo, Sean Xiao, Miao Dai, Feng He, Irene Zang, Ying Lin, Fengling Li, Elena Dobrovetsky, David Smil, Sun-Joon Min, Jennifer Lin-Jones, Matthieu Schapira, Peter Atadja, En Li, Dalia Barsyte-Lovejoy, Cheryl H Arrowsmith, Peter J Brown, Feng Liu, Zhengtian Yu, Masoud Vedadi, Jian Jin
PRMT3 catalyzes the asymmetric dimethylation of arginine residues of various proteins. It is crucial for maturation of ribosomes, and has been implicated in several diseases. We recently disclosed a highly potent, selective and cell-active allosteric inhibitor of PRMT3, compound 4. Here, we report comprehensive structure-activity relationship studies that target the allosteric binding site of PRMT3. We conducted design, synthesis and evaluation of novel compounds in biochemical, selectivity and cellular assays that culminated in the discovery of 4 and other highly potent (IC50 values: ~10-36 nM), selective and cell-active allosteric inhibitors of PRMT3 (compounds 29, 30, 36 and 37)...
December 15, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29244262/when-religion-opens-the-door-despite-the-challenges-partnerships-with-religious-and-spiritual-communities-can-address-medical-disparities-and-improve-patients-wellbeing
#16
https://www.readbyqxmd.com/read/29244250/human-innate-lymphoid-cells-ilcs-towards-a-uniform-immune-phenotyping
#17
REVIEW
Sara Trabanelli, Alejandra Gomez Cadena, Domenico Mavilio, Basile Nicolas Landis, Peter Jandus, Camilla Jandus
Helper Innate Lymphoid Cells (ILCs), the most recently identified population of the Innate Lymphoid Cell family, plays a fundamental role in the restoration of tissue integrity, in the protection against infiltrating pathogens as well as in tumor immune-surveillance. ILCs have been divided into three main subsets, ILC1, ILC2 and ILC3, that can be specifically activated by different signals coming either from pathogens or from other cell populations, including cancer cells. Following activation, ILCs are in turn able to promptly secrete a wide range of soluble mediators that modulate effector cell functions...
December 15, 2017: Cytometry. Part B, Clinical Cytometry
https://www.readbyqxmd.com/read/29244197/evaluation-of-an-online-self-help-version-of-the-reach-forgiveness-program-outcomes-and-predictors-of-persistence-in-a-community-sample
#18
Jennifer A Nation, Eleanor H Wertheim, Everett L Worthington
OBJECTIVE: We evaluated outcomes of an online, self-directed REACH forgiveness intervention for community-based adults. Because many participants dropped out before program completion, predictors of program persistence were also examined. METHOD: Participants (N = 130 adults, 122 female; mean age 48) completed pretreatment assessment and were randomized to immediate treatment (IT) or delayed treatment (DT). Twenty-three IT and 13 DT participants completed the 7-hour REACH forgiveness modules and postintervention assessment; 32 participants completed 3-month follow-up...
December 15, 2017: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/29244123/emergence-and-genomic-analysis-of-mdr-laribacter-hongkongensis-strain-hlgz1-from-guangzhou-china
#19
Hong-Kai Wu, Jian-Huan Chen, Ling Yang, A-Rong Li, Dan-Hong Su, Yong-Ping Lin, Ding-Qiang Chen
Background: Laribacter hongkongensis is a facultative anaerobic, non-fermentative, Gram-negative bacillus associated with community-acquired gastroenteritis and traveller's diarrhoea. No clinical MDR L. hongkongensis isolate has been reported yet. Methods: We performed WGS (PacBio and Illumina) on a clinical L. hongkongensis strain HLGZ1 with an MDR phenotype. Results: HLGZ1 was resistant to eight classes of commonly used antibiotics. Its complete genome was a single circular chromosome of 3 424 272 bp with a G + C content of 62...
December 13, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29244107/the-importance-of-gender-analysis-in-research-for-health-systems-strengthening
#20
Sally Theobald, Rosemary Morgan, Kate Hawkins, Sarah Ssali, Asha George, Sassy Molyneux
This editorial discusses a collection of papers examining gender across a range of health policy and systems contexts, from access to services, governance, health financing, and human resources for health. The papers interrogate differing health issues and core health systems functions using a gender lens. Together they produce new knowledge on the multiple impacts of gender on health experiences and demonstrate the importance of gender analyses and gender sensitive interventions for promoting well-being and health systems strengthening...
December 1, 2017: Health Policy and Planning
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