Talar S Habeshian, Noah C Peeri, Immaculata De Vivo, Leo J Schouten, Xiao-Ou Shu, Michele L Cote, Kimberly A Bertrand, Yu Chen, Megan A Clarke, Tess V Clendenen, Linda S Cook, Laura Costas, Luigino Dal Maso, Jo L Freudenheim, Christine M Friedenreich, Grace Gallagher, Gretchen L Gierach, Marc T Goodman, Susan J Jordan, Carlo La Vecchia, James V Lacey, Fabio Levi, Linda M Liao, Loren Lipworth, Lingeng Lu, Xavier Matías-Guiu, Kirsten B Moysich, George L Mutter, Renhua Na, Jeffin Naduparambil, Eva Negri, Kelli O'Connell, Tracy A O'Mara, Irene Onieva Hernández, Julie R Palmer, Fabio Parazzini, Alpa V Patel, Kathryn L Penney, Anna E Prizment, Fulvio Ricceri, Harvey A Risch, Carlotta Sacerdote, Sven Sandin, Rachael Z Stolzenberg-Solomon, Piet A van den Brandt, Penelope M Webb, Nicolas Wentzensen, Akemi T Wijayabahu, Lynne R Wilkens, Wanghong Xu, Herbert Yu, Anne Zeleniuch-Jacquotte, Wei Zheng, Mengmeng Du, Veronica Wendy Setiawan
BACKGROUND: The incidence rates of endometrial cancer (EC) are increasing, which may partly be explained by the rising prevalence of obesity, an established risk factor for EC. Hypertension, another component of metabolic syndrome, is also increasing in prevalence, and emerging evidence suggests that it may be associated with the development of certain cancers. The role of hypertension independent of other components of metabolic syndrome in the etiology of EC remains unclear. In this study we evaluated hypertension as an independent risk factor for EC and whether this association is modified by other established risk factors...
March 26, 2024: Cancer Epidemiology, Biomarkers & Prevention