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V Camacho, A Gómez-Grande, P Sopena, D García-Solís, M Gómez Río, C Lorenzo, S Rubí, J Arbizu
Alzheimer's disease (AD) is a neurodegenerative condition characterized by progressive cognitive decline and memory loss, and is the most common form of dementia. Amyloid plaques with neurofibrillary tangles are a neuropathological hallmark of AD that produces synaptic dysfunction and culminates later in neuronal loss. Amyloid PET is a useful, available and non-invasive technique that provides in vivo information about the cortical amyloid burden. In the latest revised criteria for the diagnosis of AD biomarkers were defined and integrated: pathological and diagnostic biomarkers (increased retention on fibrillar amyloid PET or decreased Aβ1-42 and increased T-Tau or P-Tau in CSF) and neurodegeneration or topographical biomarkers (temporoparietal hypometabolism on 18 F-FDG PET and temporal atrophy on MRI)...
May 15, 2018: Revista Española de Medicina Nuclear e Imagen Molecular
M A Balsa, V Camacho, P Garrastachu, D García-Solís, M Gómez-Río, S Rubí, X Setoain, J Arbizu
OBJECTIVE: To determine the status of neuroimaging studies of Nuclear Medicine in Spain during 2013 and first quarter of 2014, in order to define the activities of the neuroimaging group of the Spanish Society of Nuclear Medicine and Molecular Imaging (SEMNIM). MATERIAL AND METHODS: A questionnaire of 14 questions was designed, divided into 3 parts: characteristics of the departments (equipment and professionals involved); type of scans and clinical indications; and evaluation methods...
July 2017: Revista Española de Medicina Nuclear e Imagen Molecular
Rebeca Losada-Del Pozo, Verónica Cantarín-Extremera, Juan J García-Peñas, Anna Duat-Rodríguez, Laura López-Marín, Luis G Gutiérrez-Solana, M Luz Ruiz-Falcó
INTRODUCTION: Alice in Wonderland syndrome is a process characterized for complex disorders of the visual perception with multiple etiologies. AIM: To evaluate the clinical, electrophysiological, etiological characteristics and natural evolution in children with Alice in Wonderland syndrome. PATIENTS AND METHODS: We have realized a retrospective study by what means of a review of 20 clinical histories of 18 year old minor patients diagnosed of Alice in Wonderland syndrome from January 1995 until February 2010...
December 1, 2011: Revista de Neurologia
Gustavo Lorenzo-Sanz, Antonio Sánchez-Herranz
INTRODUCTION: A number of genetic and neuroimagen proofs support the idea that attention-deficit/hyperactivity disorder (ADHD) present a neurobiological alteration. Vesicular monoamine transporters (VMATs) are important proteins that regulate the intraneuronal monoamine concentration and disposition as this protein sequesters cytoplasmic dopamine within synaptic vesicles thus contributing to subsequent excitotoxic release. DEVELOPMENT: Two pharmacologically distinct VMAT isoforms VMAT1 and VMAT2 have been cloned and described...
March 1, 2011: Revista de Neurologia
L de la Cueva, E Noé, D López-Aznar, J Ferri, R Sopena, C Martínez, J Chirivella, P Abreu, E Uruburu
INTRODUCTION: To describe the changes in cerebral glucose metabolism after a severe traumatic brain injury (TBI), at the beginning of the rehabilitation, to analyze its diagnostic agreement with morphologic neuroimaging technologies (MR/CT) and to correlate the neuroimaging findings with the intensity of the TBI and the functional ability for daily activities. MATERIAL AND METHODS: Prospective study of 55 patients who had sustained a severe TBI (GCS < or = 8) by means of 18F-FDG PET and MR/CT...
March 2006: Revista Española de Medicina Nuclear
M A Segarra Soria, J Cerda Fayos, D Geffner Sclarsky, R Adell Carceller, R Salas Pascual
Heterotopia is a neuronal migration disturbance, which clinical picture is characterized by mental retardation and seizures in childhood. We present a new case, a 45 year old man without any previous clinical manifestation, and two years follow-up with neuroimagen and electroencephalographic studies.
April 1997: Anales de Medicina Interna: Organo Oficial de la Sociedad Española de Medicina Interna
M I Cebrero García, R Simón de las Heras, F Mateos Beato, J Balseiro, J Torres Mohedas
In this publish we analyze etiologic, clinic, electroencephalografic, radiologic, therapeutic and evolutionary facts of a serie of 31 children with diagnostic of West's syndrome. Advances in diagnostic methodes, overall of neuroimagen have allowed us to identify the etiology of 87% of cases, with a great variability of causes. The treatment with ACTH and/or anticonvulsive drugs was effective; although for children's prognostic, etiology and previous neurologic situation before initial symptomatology was more important...
November 1990: Archivos de Neurobiologiá
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