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https://www.readbyqxmd.com/read/29353269/clinical-characteristics-and-allergen-sensitization-patterns-of-patients-with-local-allergic-rhinitis-in-southern-china
#1
Xiao Yao Tao, Chew Lip Ng, Dong Chen, Zhi Bin Lin, Shu Lian Wu, Mei Jun Liang, Chun Wei Li, Rui Xu
BACKGROUND: Local allergic rhinitis (LAR) is characterized by the production of specific IgE (sIgE) in the nasal mucosa without evidence of systemic atopy. The characteristics of LAR in Caucasians have been well documented. LAR is understudied in China, with prevalence, patient demographics, symptomatology, and the allergen sensitization profile being poorly understood. The purpose of this study is to investigate the demographics, characteristics, and allergen sensitization profile of patients with LAR in Southern China...
January 20, 2018: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/29350800/acquisition-remission-and-persistence-of-eczema-asthma-and-rhinitis-in-children
#2
Hongmei Zhang, Akhilesh Kaushal, Nelís Soto-Ramírez, Ali H Ziyab, Susan Ewart, John W Holloway, Wilfried Karmaus, Hasan Arshad
BACKGROUND: Allergic sensitization is associated with eczema, asthma, and rhinitis. However, it is unknown whether and how allergic sensitization is associated over time with acquisition, remission, and persistence of these diseases and their comorbidity. OBJECTIVE: To gain a better understanding of factors including allergic sensitization transitions that influence the temporal pattern of asthma, eczema, and rhinitis and their comorbidity during childhood. METHODS: In the Isle of Wight birth cohort information on allergic sensitization to common allergens was collected at ages 4, 10, and 18 years along with asthma, rhinitis, and eczema status determined by clinical diagnosis...
January 19, 2018: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29350019/cypress-pollen-allergy-is-responsible-for-two-distinct-phenotypes-of-allergic-rhinitis-different-from-other-pollinosis
#3
L Pahus, M Gouitaa, T Sofalvi, K Alagha, D Gras, P Chanez, D Charpin
Different phenotypes of allergic rhinitis have been identified based on the seasonality of the allergen involved. Within pollinosis, importance has to be paid to the responsible pollen species. Guidelines for clinical management are mostly based on studies performed in patients with grass pollen allergy. Only few data is available on tree pollen allergy and more specifically on cypress pollen allergy. We focused on the clinical and biological features of cypress pollen allergy to determine whether it is associated with a specific phenotype of allergic rhinitis or not...
January 2018: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29350017/skin-prick-test-analysis-reveals-cross-sensitization-to-tomato-profilin-and-grass-pollen-in-nasobronchialallergic-patients-with-history-of-tomato-food-allergy
#4
V L Hegde, P A Mahesh, Y P Venkatesh
The association between grass pollen sensitization and food allergy to tomato is of great interest. We report here, the first such study in Indian population. We investigated 246 allergic rhinitis / asthma patients by diagnostic case history and skin prick test (SPT); grass pollen mix, tomato extract and purified tomato profilin were used for SPT. Tomato profilin was purified by affinity chromatography, and analyzed by HPLC (95% purity) and SDS-PAGE (14 kDa). We observed that 38% of the patients had sensitization to both grass pollen and tomato fruit, of which 92% were sensitized to tomato profilin...
January 2018: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29350016/biomarkers-of-treatment-efficacy-in-patients-with-chronic-spontaneous-urticaria
#5
M Sánchez-Borges, A Capriles-Hulett, F Caballero-Fonseca, L González-Aveledo
Background. Currently there are no biomarkers useful to predict the future evolution and the therapeutic response in patients with chronic spontaneous urticaria (CSU). Objective. To review the available information on biomarkers that might be applied for the follow up of the response to guideline recommended therapies for CSU. Methods. A review of the medical literature on CSU potential clinical and laboratory biomarkers in PubMed and MEDLINE including the terms urticaria, chronic urticaria, chronic idiopathic urticaria, chronic spontaneous urticaria, antihistamines (AHs), omalizumab (OMA), cyclosporine (CyA), and treatment...
January 2018: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29349047/reduction-of-the-isolated-anterior-wall-of-the-maxillary-sinus-fracture-with-double-urinary-balloon-catheters-and-fibrin-glue
#6
Jaehee Kim, Ho Jik Yang, Jong Hwan Kim, Su Jin Kim
Background: Conservative treatment is performed for isolated anterior wall of the maxillary sinus fractures, in many cases when the fracture is clinically not severe and asymptomatic. Despite the absence of symptoms, complications such as sinusitis, rhinitis, and chronic purulent secretion may develop; therefore, successful reduction is required. We attempted to reduce the risk of complications using an alternative technique: reduction of the fracture with two urinary balloon catheters inserted through the maxillary ostium and fixation using fibrin glue, which minimizes the damage to the bony fragments and sinus mucosa...
December 2017: Archives of Craniofacial Surgery
https://www.readbyqxmd.com/read/29348379/the-differences-in-serum-quantitative-specific-ige-levels-induced-by-dermatophagoides-pteronyssinus-dermatophagoides-farinae-and-blomia-tropicalis-sensitization-in-intermittent-and-persistent-allergic-asthma
#7
Agus Joko Susanto, Iris Rengganis, Cleopas M Rumende, Kuntjoro Harimurti
BACKGROUND: house dust mites (HDM) are an important inhalant allergen in allergic asthma. However, molecular diagnostic study of specific IgE to HDM allergens has not been done in Indonesia. In addition, the association of quantitative specific IgE measurement with asthma severity has not been investigatedd. This study aimed to investigate the difference of serum quantitative specific IgE levels induced by Dermatophagoides (D.) pteronyssinus, D. farinae and Blomia tropicalis sensitization in intermittent and persistent allergic asthma...
October 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/29348359/complete-genome-sequence-of-the-type-strain-of-macrococcus-canis
#8
Stefanie Gobeli Brawand, Lorenz Rychener, Sybille Schwendener, Roman Pantůček, Vincent Perreten
The first complete genome sequence of the recently described Macrococcus canis species has been determined for the strain KM45013T (=DSM 101690T = CCOS 969T = CCUG 68920T = CCM 8748T). The strain was isolated from a dog with rhinitis and contains a putative γ-hemolysin and a mecB-carrying staphylococcal cassette chromosome mec element (SCCmecKM45013).
January 18, 2018: Genome Announcements
https://www.readbyqxmd.com/read/29343309/could-seasonal-allergy-be-a-risk-factor-for-acute-rhinosinusitis-in-children
#9
G Leo, C Incorvaia, A Cazzavillan, D Consonni, G V Zuccotti
OBJECTIVE: To evaluate the incidence of acute rhinosinusitis in children with grass pollen induced rhinitis during the period of grass pollinosis. METHODS: Children with nasal symptoms from grass pollen induced rhinitis but without rhinosinusitis symptoms were selected. Their parents were asked to complete a diary during pollen exposure to report nasal symptoms and drugs used daily. When rhinosinusitis was suspected, the confirmatory diagnosis of acute rhinosinusitis was made by fibro-endoscopy...
January 18, 2018: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/29343306/nasal-changes-associated-with-exercise-in-athletes-systematic-review
#10
P Surda, A Walker, J Limpens, W Fokkens, M Putala
BACKGROUND: The prevalence of rhinitis in athletes has frequently been studied in combination with asthma, but the impact of exercise on the paracrine and secretory functions of nasal mucosa is less well established. This systematic review aimed to examine the effect of exercise on nasal mucosa in elite athletes. METHOD: A systematic search of Medline, Embase and the non-Medline subset of PubMed, from inception to 8th March 2016, was performed to identify studies on rhinitis in athletes...
January 18, 2018: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/29341484/nasal-ventilation-is-an-important-factor-in-evaluating-the-diagnostic-value-of-nasal-nitric-oxide-in-allergic-rhinitis
#11
Jing Hou, Hongfei Lou, Yang Wang, Fei He, Feifei Cao, Chengshuo Wang, Luo Zhang
BACKGROUND: The role of nasal nitric oxide (NO) in the diagnosis of allergic rhinitis (AR) is controversial. The aim of this study was to identify factors that may affect levels of nasal NO in AR patients and evaluate the role of nasal NO in the diagnosis of AR. METHODS: Seventy-five AR patients and 31 healthy controls were enrolled in this study. AR symptom scores were assessed using the visual analog scale. Eosinophil cationic protein (ECP) was detected by enzyme-linked immunoassay, nasal NO was measured using a chemiluminescence analyzer, and nasal airway resistance (NAR) was assessed by active anterior rhinomanometry...
January 17, 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29341029/in-vitro-and-in-situ-absorption-and-metabolism-of-sesquiterpenes-from-petasites-hybridus-extracts
#12
Lucia Disch, Kristina Forsch, Beate Siewert, Jürgen Drewe, Gert Fricker
Petasites hybridus extract is used in the treatment of seasonal allergic rhinitis. The aim of this study was to evaluate the active constituent petasin and its isomers isopetasin and neopetasin (petasins) in the P. hybridus extract Ze 339 for liberation, dissolution, absorption, and metabolism. The determination of pH-dependent thermodynamic solubility was performed via the shake-flask method. Petasins exhibited a low solubility that was pH independent. In vivo, the concentration of solute drugs is decreased continuously by intestinal absorption...
January 16, 2018: Planta Medica
https://www.readbyqxmd.com/read/29338964/validation-of-the-children-s-sleep-habits-questionnaire-in-a-sample-of-greek-children-with-allergic-rhinitis
#13
A Mavroudi, E-A Chrysochoou, R J Boyle, G Trypsianis, I Xinias, D Cassimos, G Imvrios, M Katotomichelakis, A Karagiannidou, N Karantaglis, G Kourentas, J O Warner
BACKGROUND: Obstructive respiratory disorders, such as allergic rhinitis and asthma may impair sleep quality. The aim of this study is to validate the Children's Sleep Habits Questionnaire (CSHQ) for Greek children from 6 to 14 years of age. No validated tool has been developed so far to assess sleep disturbances in Greek school-aged children. METHODS: We examined the reliability and validity of the CSHQ in a sample of children with allergic rhinitis (AR) and a non-clinical population of parents of these children as a proxy measure of children's AR quality of life (QoL) as evaluated by the Pediatric Allergic Rhinitis Quality of Life (PedARQoL) questionnaire...
January 12, 2018: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/29338960/small-airway-dysfunction-precedes-the-development-of-asthma-in-children-with-allergic-rhinitis
#14
E Skylogianni, M Triga, K Douros, K Bolis, K N Priftis, S Fouzas, M B Anthracopoulos
BACKGROUND: Epidemiological evidence suggests the existence of a direct link between allergic rhinitis (AR) and asthma. Several studies also support the presence of small-airway dysfunction (SAD) in non-asthmatic children with AR. However, it remains unknown whether SAD can predict the progression of AR to asthma. Our objective was to explore the existence of SAD in non-asthmatic children with AR and to assessed its ability to predict the development of asthma. METHODS: Seventy-three 6-year-old children with intermittent moderate-severe AR but without asthma symptoms/medication within the last two years, underwent spirometry and measurement of respiratory resistance (Rrs) and reactance (Xrs) before and after bronchodilation (BD) (300mcg salbutamol)...
January 12, 2018: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/29337654/oral-antihistamines-alone-vs-in-combination-with-leukotriene-receptor-antagonists-for-allergic-rhinitis-a-meta-analysis
#15
Guo Liu, Xu Zhou, Jianrong Chen, Feng Liu
Objective To evaluate whether an adjuvant therapy of leukotriene receptor antagonists (LTRAs) based on oral H1-antihistamines (H1) can increase efficacy of allergic rhinitis (AR) treatment. Data Sources The search involved databases of PubMed, EMBASE, and Cochrane Central Register of Controlled Trials, from inception up to September 23, 2017. Randomized controlled trials (RCTs) that compared efficacy of LTRAs + H1 vs H1 alone were eligible. Review Methods Pooled comparative effects were measured using weighted mean difference (WMD) and 95% confidence interval (CI)...
January 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29336285/optimal-cutoff-values-of-allergen-specific-immunoglobulin-e-to-house-dust-mites-and-animal-dander-based-on-skin-prick-test-results-analysis-in-16-209-patients-with-allergic-rhinitis
#16
Sang Duk Hong, Gwanghui Ryu, Min Young Seo, Jong In Jeong, Hyo Yeol Kim, Seung-Kyu Chung, Hun-Jong Dhong
BACKGROUND: The most common tests for allergen sensitization in patients with allergic rhinitis are the skin-prick test (SPT) and an in vitro test to detect serum specific immunoglobulin E (sIgE). However, in vitro allergen test results were interpreted dichotomically as positive or negative at a threshold of 0.35 kU/L of sIgE, regardless of the patient characteristics or antigen types. OBJECTIVE: The purpose of this study was to determine the cutoff value for sIgE in house-dust mites and animal dander, and to analyze differences in cutoff value according to age and gender...
January 25, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29336284/assessing-the-onset-of-allergic-rhinitis-by-nasal-cytology-and-immunoglobulin-e-antibody-levels-in-children
#17
Hirokuni Otsuka, Kuninori Otsuka, Shoji Matsune, Kimihiro Okubo
BACKGROUND: It is difficult to identify the onset of allergic rhinitis in infants because making a conclusive diagnosis can be challenging. OBJECTIVE: We used a combination of cell differentials in nasal swabs and immunoglobulin E (sIgE) antibody values to food and inhalant allergens to make the diagnosis and identify relevant allergens for investigation of the onset of allergic rhinitis. METHODS: We studied 302 children, 2 to 120 months old, who visited our clinic for rhinorrhea...
January 1, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29336067/treatment-of-allergic-rhinitis-using-mobile-technology-with-real-world-data-the-mask-observational-pilot-study
#18
REVIEW
J Bousquet, S Arnavielhe, A Bedbrook, G Alexis-Alexandre, M van Eerd, R Murray, G W Canonica, M Illario, E Menditto, G Passalacqua, C Stellato, M Triggiani, P Carreiro-Martins, J Fonseca, M Morais Almeida, L Nogueira-Silva, A M Pereira, A Todo Bom, I Bosse, D Caimmi, P Demoly, P Devillier, J F Fontaine, J Just, G L Onorato, M L Kowalski, P Kuna, B Samolinski, J M Anto, J Mullol, A Valero, P V Tomazic, K C Bergmann, T Keil, L Klimek, R Mösgues, S Shamai, T Zuberbier, E Murphy, Peter McDowall, D Price, D Ryan, A Sheikh, N H Chavannes, W J Fokkens, V Kvedariene, A Valiulis, C Bachert, P W Hellings, I Kull, E Melén, M Wickman, C Bindslev-Jensen, E Eller, T Haahtela, E Valovirta, N G Papadopoulos, I Annesi-Maesano, M Bewick, S Bosnic-Anticevich, A A Cruz, G De Vries, B Gemicioglu, D Larenas-Linnemann, D Laune, E Mathieu-Dupas, R E O'Hehir, F Portejoie, V Siroux, O Spranger, O VandenPlas, A Yorgancioglu
BACKGROUND: Large observational implementation studies are needed to triangulate the findings from randomized control trials (RCTs) as they reflect "real world" everyday practice. In a pilot study, we attempted to provide additional and complementary insights on the real life treatment of allergic rhinitis using mobile technology. METHODS: A mobile phone app (Allergy Diary, freely available Google Play and Apple App stores) collects the data of daily visual analogue scales (VAS) for (i) overall allergic symptoms, (ii) nasal, ocular and asthma symptoms, (iii) work, as well as (iv) medication use using a treatment scroll list including all medications (prescribed and over the counter (OTC)) for rhinitis customized for 15 countries...
January 15, 2018: Allergy
https://www.readbyqxmd.com/read/29334241/transcriptional-regulation-on-the-gene-expression-signature-in-combined-allergic-rhinitis-and-asthma-syndrome
#19
Zhengdao Mao, Yujia Shi, Qi Cao, Yi Chen, Yun Sun, Zhiguang Liu, Qian Zhang, Mao Huang
AIM: This study was intended to evaluate transcriptional regulation of gene expression signatures in combined allergic rhinitis and asthma syndrome (CARAS). MATERIALS & METHODS: The blood samples of three patients with CARAS, three patients with allergic rhinitis and three normal controls were obtained. The cuffdiff, miRDeep2 and DEGseq were used to quantify the expression of genes and miRNAs, respectively. And p-value < 0.01 and false discovery rate < 0...
January 15, 2018: Epigenomics
https://www.readbyqxmd.com/read/29331618/efficacy-and-safety-of-sublingual-immunotherapy-with-dermatophagoides-farinae-drops-in-pre-school-and-school-age-children-with-allergic-rhinitis
#20
L-X Tang, X-J Yang, P-P Wang, W-T Ge, J Zhang, Y-L Guo, J Lu, J Tai, Y-M Zhang, X Ni
BACKGROUND: The safety and efficacy of sublingual immunotherapy (SLIT) have been confirmed by many studies. However, in China, the research on efficacy and safety in young and older children with allergic rhinitis (AR) is still rare. OBJECTIVE: The aim of this retrospective study is to evaluate the efficacy and safety of SLIT with Dermatophagoides farinae drops in pre-school and school-age children with AR. METHODS: A total of 282 subjects aged 2-13 years with AR received a two-year course of sublingual immunotherapy along with pharmacotherapy...
January 10, 2018: Allergologia et Immunopathologia
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