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https://www.readbyqxmd.com/read/28935380/-factors-associated-with-asthma-in-children-and-adolescents-in-rural-areas-of-navarre-spain
#1
Itsaso Elizalde-Beiras, Francisco Guillén-Grima, Inés Aguinaga-Ontoso
OBJECTIVES: To determine the factors associated with asthma and asthma-related symptoms in children and adolescents in rural areas of Navarre (Spain). PARTICIPANTS AND METHODS: A cross-sectional study using the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire, as well as additional variables, was conducted on 797 children and adolescents. These provided prevalence data on asthma symptoms and associated factors without further diagnostic testing...
September 18, 2017: Atencion Primaria
https://www.readbyqxmd.com/read/28932387/peak-nasal-inspiratory-flow-as-outcome-for-provocation-studies-in-allergen-exposure-chambers-a-ga-2-len-study
#2
Georg Boelke, Uwe Berger, Karl-Christian Bergmann, Carsten Bindslev-Jensen, Jean Bousquet, Julia Gildemeister, Marek Jutel, Oliver Pfaar, Torsten Sehlinger, Torsten Zuberbier
BACKGROUND: The GA(2)LEN chamber has been developed as a novel mobile allergen exposure chamber (AEC) allowing standardized multicenter trials in allergy. Hitherto, subjective nasal symptom scores have been the most often used outcome parameter, but in standardized modern trials objective parameters are preferred. Despite its practicability, the objective parameter peak nasal inspiratory flow (PNIF) has been rarely used for allergy trials in the setting of allergen exposure chambers. This study aims to evaluate PNIF as an outcome parameter for provocation studies in AECs...
2017: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/28932345/the-grass-pollen-season-2015-a-proof-of-concept-multi-approach-study-in-three-different-european-cities
#3
Maximilian Kmenta, Katharina Bastl, Uwe Berger, Matthias F Kramer, Matthew D Heath, Sanna Pätsi, Anna-Mari Pessi, Annika Saarto, Barbora Werchan, Matthias Werchan, Reinhard Zetter, Karl-Christian Bergmann
BACKGROUND: Grasses release the most widespread aeroallergens with considerable sensitization rates, while different species produce several pollen concentration peaks throughout the season. This study analyzed the prevalence of grass species in three different European city areas and compared the flowering period of these species with daily pollen concentrations and the symptom loads of grass pollen allergy sufferers. METHODS: The most prevalent grass species in Vienna (Austria), Berlin (Germany) and Turku (Finland) were studied and examined by use of three different approaches: phenology, pollen monitoring and symptom load evaluation...
2017: World Allergy Organization Journal
https://www.readbyqxmd.com/read/28931869/dermatophagoides-pteronyssinus-immunotherapy-changes-the-t-regulatory-cell-activity
#4
M Gonzalez, I Doña, F Palomares, P Campo, M J Rodriguez, C Rondon, F Gomez, T D Fernandez, J R Perkins, M M Escribese, M J Torres, C Mayorga
Subcutaneous specific immunotherapy (SCIT) has been shown to modify the Dermatophagoides pteronissinus (DP) allergic response, characterized by generation of Treg cells. However, studies have reported no changes in the proportion of Treg cells after immunotherapy, indicating that the effects may be due to modifications in their regulatory activities. We aimed to determine whether Tregs generated by DP-SCIT can switch the allergic response to tolerant and study the involvement of suppressive cytokines on it...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28929717/-thunderstorm-and-asthma-outbreaks-during-pollen-season
#5
Maria D'Amato, Isabella Annesi-Maesano, Antonio Molino, Mauro Mormile, Carolina Vitale, Alessandro Vatrella, Alessandro Sanduzzi, Gennaro D'Amato
An increasing body of evidence shows the occurrence of asthma epidemics, sometimes also severe, during thunderstorms in the pollen season in various geographical zones. The main hypothesis explaining association between thunderstorms and asthma claims that thunderstorms can concentrate pollen grains at ground level; these grains may then release allergenic particles of respirable size in the atmosphere after their rupture by osmotic shock. During the first 20-30 minutes of a thunderstorm, patients suffering from pollen allergy may inhale a high concentration of the allergenic material dispersed into the atmosphere, which can, in turn, induce asthmatic reactions, often severe...
May 2017: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/28928804/efficacy-of-a-leukotriene-receptor-antagonist-for-pediatric-cedar-pollen-allergy-complicated-by-asthma
#6
Shigemi Yoshihara, Yutaka Kikuchi, Mari Saitou, Susumu Yanagawa, Noriko Kanno, Hiroshi Igarashi, Hironobu Fukuda, Akiko Iimura, Toshio Abe, Yumi Yamada, Tamotsu Andou, Osamu Arisaka
Leukotriene receptor antagonists (LTRAs) are identified as a monotherapy for asthma and allergic rhinitis; however, their use in children for treatment of these diseases has not been examined. Accordingly, the present study investigated the efficacy of pranlukast dry syrup for children with both pollinosis and asthma. The subjects were children receiving treatment for asthma who were also diagnosed with cedar pollen allergy. Patients were divided into a group that received continuous treatment with pranlukast (group A; n=20) and a group that commenced add-on treatment for pollinosis following the onset of symptoms (group B; n=20)...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28926718/corrigendum
#7
(no author information available yet)
Brunner JP, Jawad BA, McCoul ED. Polypoid change of the middle turbinate and paranasal sinus polyposis are distinct entities. Otolaryngol Head Neck Surg. 2017;157:519-523. (Original doi: 10.1177/0194599817711887) The Results section of this article and its abstract contained several errors in describing data that appears in Tables 1 and 2. The tables contain the correct information, the corrected abstract and article text appears below. Abstract: Results. Of 593 patients, 23 (3.9%) had PCMT and 44 (7.4%) had PSP...
September 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28919832/seasonal-patterns-of-oral-antihistamine-and-intranasal-corticosteroid-purchases-from-australian-community-pharmacies-a-retrospective-observational-study
#8
A Simon Carney, David B Price, Pete K Smith, Richard Harvey, Vicky Kritikos, Sinthia Z Bosnic-Anticevich, Louise Christian, Derek A Skinner, Victoria Carter, Alice Ms Durieux
PURPOSE: To explore patterns in the purchase of prescription and over-the-counter (OTC) oral antihistamines (OAHs) and intranasal corticosteroids (INCSs) by patients, from pharmacies in different geographical regions of Australia. PATIENTS AND METHODS: Retrospective observational study using a database containing anonymous pharmacy transaction data from 20.0% of the pharmacies in Australia that link doctor prescriptions and OTC information. Pharmacy purchases of at least one prescription or OTC rhinitis treatment during 2013 and 2014 were assessed...
2017: Pragmatic and Observational Research
https://www.readbyqxmd.com/read/28918658/the-role-of-upper-airway-pathology-as-a-co-morbidity-in-severe-asthma
#9
Amelia Licari, Ilaria Brambilla, Maria De Filippo, Dimitri Poddighe, Riccardo Castagnoli, Gian Luigi Marseglia
Severe asthma is a complex heterogeneous disease that is refractory to standard treatment and is complicated by multiple co-morbidities and risk factors. Several co-morbidities may contribute to worsen asthma control and complicate diagnostic and therapeutic management of severe asthmatic patients. Areas covered: A prevalent cluster of chronic upper airway co-morbid diseases is recognized in severe asthma. Evaluation for these disorders should always be considered in clinical practice. The aim of this review is to provide an updated overview of the prevalence, the pathogenetic mechanisms, the clinical impact and the therapeutic options for upper airway pathology in severe asthma, focusing on chronic rhinosinusitis and allergic rhinitis...
September 16, 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/28917723/increased-innate-type-2-immune-response-in-house-dust-mite-allergic-patients-with-allergic-rhinitis
#10
Hua Zhong, Xing-Liang Fan, Qiu-Ning Yu, Zi-Li Qin, Dong Chen, Rui Xu, De-Hua Chen, Zhi-Bin Lin, Weiping Wen, Qing-Ling Fu
Group 2 innate lymphoid cells (ILC2s) are essential in initiating and driving allergic immune responses. However, there were inconsistent findings of the ILC2 levels in allergic rhinitis (AR) patients. This study investigated the ILC2 levels in the peripheral blood of house dust mite (HDM)-allergic AR patients and their ability to secrete type 2 cytokines. The levels of ILC2s with phenotypic ILC2 characteristics were increased in the HDM-AR patients. The AR patients' symptom score and IL-13 levels were positively associated with the ILC2s in HDM-AR patients...
September 13, 2017: Clinical Immunology: the Official Journal of the Clinical Immunology Society
https://www.readbyqxmd.com/read/28915242/a-retrospective-cost-analysis-of-additional-homeopathic-treatment-in-germany-long-term-economic-outcomes
#11
Julia K Ostermann, Claudia M Witt, Thomas Reinhold
OBJECTIVES: This study aimed to provide a long-term cost comparison of patients using additional homeopathic treatment (homeopathy group) with patients using usual care (control group) over an observation period of 33 months. METHODS: Health claims data from a large statutory health insurance company were analysed from both the societal perspective (primary outcome) and from the statutory health insurance perspective (secondary outcome). To compare costs between patient groups, homeopathy and control patients were matched in a 1:1 ratio using propensity scores...
2017: PloS One
https://www.readbyqxmd.com/read/28913994/mouse-model-of-il-17-dominant-rhinitis-using-polyinosinic-polycytidylic-acid
#12
Jun Sang Bae, Eun Hee Kim, Ji Hye Kim, Ji Hun Mo
Interleukin (IL)-17 plays an important role in rhinitis and the level thereof correlates with the severity of disease. However, no mouse model for IL-17-dominant rhinitis has yet been developed. Our objective was to establish a mouse model of IL-17-dominant rhinitis via intranasal application of polyinosinic-polycytidylic acid (abbreviated as Poly(I:C)). Mice were divided into 6 groups (n=8 for each group); 1) 1 negative control group, 2) 1 positive control group (OVA/alum model), 3) 2 Poly(I:C) groups (10 or 100 μg), and 4) 2 OVA/Poly(I:C) groups (10 or 100 μg)...
November 2017: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/28913993/a-retrospective-study-of-korean-adults-with-food-allergy-differences-in-phenotypes-and-causes
#13
So Hee Lee, Ga Young Ban, Kyunguk Jeong, Yoo Seob Shin, Hae Sim Park, Sooyoung Lee, Young Min Ye
PURPOSE: Increasing in prevalence, food allergy (FA) is becoming an important public health concern. In Korean adults, however, clinical phenotypes and causes of FA have not been studied. We aimed to study common causative allergens and clinical manifestations of FA in Korean adults. METHODS: This study was conducted as a retrospective review of medical records for 95 patients (≥19 years old) diagnosed with FA from September 2014 to August 2015 at a single university hospital...
November 2017: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/28913986/chronic-spontaneous-urticaria-pathogenesis-and-treatment-considerations
#14
REVIEW
Allen P Kaplan
The treatment of chronic spontaneous urticaria begins with antihistamines; however, the dose required typically exceeds that recommended for allergic rhinitis. Second-generation, relatively non-sedating H₁-receptor blockers are typically employed up to 4 times a day. First-generation antihistamines, such as hydroxyzine or diphenhydramine (Atarax or Benadryl), were employed similarly in the past. Should high-dose antihistamines fail to control symptoms (at least 50%), omalizumab at 300 mg/month is the next step...
November 2017: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/28912627/il-25-could-be-involved-in-the-development-of-allergic-rhinitis-sensitized-to-house-dust-mite
#15
Dae Woo Kim, Dong-Kyu Kim, Kyoung Mi Eun, Jun-Sang Bae, Young-Jun Chung, Jun Xu, Yong Min Kim, Ji-Hun Mo
BACKGROUND AND PURPOSE: When house dust mite (HDM), a common allergen, comes into the mucosal membrane, it may stimulate innate immunity. However, the precise role of interleukin- (IL-) 25 in the development of HDM-induced nasal allergic inflammation is still unclear. Therefore, we investigated the role of IL-25 in allergic rhinitis (AR) patients sensitized to HDM. METHODS: To confirm the production of IL-25 in human nasal epithelial cells (HNECs), we stimulated HNECs...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/28912588/lipopolysaccharide-initiated-persistent-rhinitis-causes-gliosis-and-synaptic-loss-in-the-olfactory-bulb
#16
Sanae Hasegawa-Ishii, Atsuyoshi Shimada, Fumiaki Imamura
The olfactory mucosa (OM) is exposed to environmental agents and therefore vulnerable to inflammation. To examine the effects of environmental toxin-initiated OM inflammation on the olfactory bulb (OB), we induced persistent rhinitis in mice and analyzed the spatial and temporal patterns of histopathological changes in the OM and OB. Mice received unilateral intranasal administration of lipopolysaccharide (LPS) or saline three times per week, and were immunohistologically analyzed at 1, 3, 7, 14 and 21 days after the first administration...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28912020/intestinal-dysbiosis-featuring-abundance-of-ruminococcus-gnavus-associates-with-allergic-diseases-in-infants
#17
Huey-Huey Chua, Hung-Chieh Chou, Ya-Ling Tung, Bor-Luen Chiang, Chien-Chia Liao, Hong-Hsing Liu, Yen-Hsuan Ni
BACKGROUND & AIMS: Dysbiosis of the intestinal microbiota has been associated with development of allergies in infants. However, it is not clear what microbes might contribute to this process. We investigated what microbe(s) might be involved in analyses of infant twins and mice. METHODS: We studied fecal specimens prospectively in a twin cohort (n=30) and age-matched singletons (n=14) born at National Taiwan University Children's Hospital, Taipei, Taiwan, from April 2011 to March 2013...
September 11, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28906011/the-aria-score-of-allergic-rhinitis-using-mobile-technology-correlates-with-quality-of-life-the-mask-study
#18
J Bousquet, S Arnavielhe, A Bedbrook, J Fonseca, M Morais Almeida, A Todo Bom, I Annesi-Maesano, D Caimmi, P Demoly, P Devillier, V Siroux, E Menditto, G Passalacqua, C Stellato, M T Ventura, A A Cruz, F S Serpa, J da Silva, D Larenas-Linnemann, M Rodriguez Gonzalez, M T Burguete Cabañas, K C Bergmann, T Keil, L Klimek, R Mösges, S Shamai, T Zuberbier, M Bewick, D Price, D Ryan, A Sheikh, J M Anto, J Mullol, A Valero, T Haahtela, E Valovirta, W J Fokkens, P Kuna, B Samolinski, C Bindslev-Jensen, E Eller, S Bosnic-Anticevich, R E O'Hehir, P V Tomazic, A Yorgancioglu, B Gemicioglu, C Bachert, P W Hellings, I Kull, E Melén, M Wickman, M van Eerd, G De Vries
Mobile technology has been used to appraise allergic rhinitis control but more data are needed. In order to better assess the importance of mobile technologies in rhinitis control, the ARIA (Allergic Rhinitis and its Impact on Asthma) score ranging from 0 to 4 of the Allergy Diary was compared with EQ-5D (EuroQuol) and WPAI-AS (Work Productivity and Activity Impairment in allergy) in 1,288 users in 18 countries. This study showed that quality-of-life data (EQ-5D visual analogue scale and WPA-IS Question 9) are similar in users without rhinitis and in those with mild rhinitis (scores 0-2)...
September 14, 2017: Allergy
https://www.readbyqxmd.com/read/28904968/the-prevalence-of-ocular-allergy-and-comorbidities-in-chinese-school-children-in-shanghai
#19
Yanqing Feng, Xiangning Wang, Fang Wang, Rongming Liu, Lu Chen, Shuqin Wu, Xia Yang, Miaoying Chen, Yu-Qing Rao, Jing Li
OBJECTIVE: To investigate the prevalence and features of ocular allergy (OA) and comorbidities among school children in Shanghai, China. METHODS: This was a population-based cross-sectional study. Each participant completed an ISAAC-based questionnaire. The prevalence of OA symptoms, allergic rhinitis (AR) asthma, atopic dermatitis (AD), and sensitization to mites, pollen, and food was analyzed. RESULTS: A total of 724 and 942 completed questionnaires from the 7-9-year-old (young group) and the 12-14-year-old (teen group) groups were analyzed, respectively...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28904285/obesity-and-atopic-dermatitis-allergic-rhinitis
#20
Takashi Kusunoki
No abstract text is available yet for this article.
2017: Arerugī, [Allergy]
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