Michael Linecker, Florin Botea, Dimitri Aristotele Raptis, Diana Nicolaescu, Përparim Limani, Ruslan Alikhanov, Pavel Kim, Andrea Wirsching, Philipp Kron, Marcel A Schneider, Christoph Tschuor, Patryk Kambakamba, Christian Oberkofler, Michelle L De Oliveira, John Bonvini, Michail Efanov, Rolf Graf, Henrik Petrowsky, Igor Khatkov, Pierre-Alain Clavien, Irinel Popescu
BACKGROUND & AIMS: In a variety of animal models, omega-3 polyunsaturated fatty acids (Ω3-FAs) conferred strong protective effects, alleviating hepatic ischemia/reperfusion injury and steatosis, as well as enhancing regeneration after major tissue loss. Given these benefits along with its safety profile, we hypothesized that perioperative administration of Ω3-FAs in patients undergoing liver surgery may ameliorate the postoperative course. The aim of this study was to investigate the perioperative use of Ω3-FAs to reduce postoperative complications after liver surgery...
March 2020: Journal of Hepatology