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https://www.readbyqxmd.com/read/28343328/skeletal-development-of-the-hand-and-wrist-digital-bone-age-companion-a-suitable-alternative-to-the-greulich-and-pyle-atlas-for-bone-age-assessment
#1
Paul M Bunch, Talissa A Altes, Joan McIlhenny, James Patrie, Cree M Gaskin
PURPOSE: To assess reader performance and subjective workflow experience when reporting bone age studies with a digital bone age reference as compared to the Greulich and Pyle atlas (G&P). We hypothesized that pediatric radiologists would achieve equivalent results with each method while digital workflow would improve speed, experience, and reporting quality. MATERIALS AND METHODS: IRB approval was obtained for this HIPAA-compliant study. Two pediatric radiologists performed research interpretations of bone age studies randomized to either the digital (Digital Bone Age Companion, Oxford University Press) or G&P method, generating reports to mimic clinical workflow...
March 25, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28343309/breast-cancer-detection-and-tumor-characteristics-in-brca1-and-brca2-mutation-carriers
#2
Julia Krammer, Katja Pinker-Domenig, Mark E Robson, Mithat Gönen, Blanca Bernard-Davila, Elizabeth A Morris, Debra A Mangino, Maxine S Jochelson
PURPOSE: To describe imaging findings, detection rates, and tumor characteristics of breast cancers in a large series of patients with BRCA1 and BRCA2 mutations to potentially streamline screening strategies. METHODS: An IRB-approved, HIPAA-compliant retrospective analysis of 496 BRCA mutation carriers diagnosed with breast carcinoma from 1999 to 2013 was performed. Institutional database and electronic medical records were reviewed for mammography and MRI imaging...
March 25, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28323377/accuracy-of-pdff-estimation-by-magnitude-based-and-complex-based-mri-in-children-with-mr-spectroscopy-as-a-reference
#3
William M Haufe, Tanya Wolfson, Catherine A Hooker, Jonathan C Hooker, Yesenia Covarrubias, Alex N Schlein, Gavin Hamilton, Michael S Middleton, Jorge E Angeles, Diego Hernando, Scott B Reeder, Jeffrey B Schwimmer, Claude B Sirlin
PURPOSE: To assess and compare the accuracy of magnitude-based magnetic resonance imaging (MRI-M) and complex-based MRI (MRI-C) for estimating hepatic proton density fat fraction (PDFF) in children, using MR spectroscopy (MRS) as the reference standard. A secondary aim was to assess the agreement between MRI-M and MRI-C. MATERIALS AND METHODS: This was a HIPAA-compliant, retrospective analysis of data collected in children enrolled in prospective, Institutional Review Board (IRB)-approved studies between 2012 and 2014...
March 21, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28301777/vertebral-body-compression-fractures-and-bone-density-automated-detection-and-classification-on-ct-images
#4
Joseph E Burns, Jianhua Yao, Ronald M Summers
Purpose To create and validate a computer system with which to detect, localize, and classify compression fractures and measure bone density of thoracic and lumbar vertebral bodies on computed tomographic (CT) images. Materials and Methods Institutional review board approval was obtained, and informed consent was waived in this HIPAA-compliant retrospective study. A CT study set of 150 patients (mean age, 73 years; age range, 55-96 years; 92 women, 58 men) with (n = 75) and without (n = 75) compression fractures was assembled...
March 16, 2017: Radiology
https://www.readbyqxmd.com/read/28296979/feasibility-of-assessing-bone-matrix-and-mineral-properties-in-vivo-by-combined-solid-state-1h-and-31p-mri
#5
Xia Zhao, Hee Kwon Song, Alan C Seifert, Cheng Li, Felix W Wehrli
PURPOSE: To develop and evaluate an integrated imaging protocol for bone water and phosphorus quantification in vivo by solid-state 1H and 31P MRI. MATERIALS AND METHODS: All studies were HIPAA-compliant and were performed with institutional review board approval and written informed consent. Proton (1H) ultra-short echo-time (UTE) and phosphorus (31P) zero echo-time (ZTE) sequences were designed and implemented on a 3 T clinical MR scanner to quantify bone water and mineral in vivo...
2017: PloS One
https://www.readbyqxmd.com/read/28291311/the-hipaa-security-rule-are-you-in-compliance
#6
Daniel F Shay
No abstract text is available yet for this article.
March 2017: Family Practice Management
https://www.readbyqxmd.com/read/28281784/image-quality-of-cone-beam-computed-tomography-for-evaluation-of-extremity-fractures-in-the-presence-of-metal-hardware-visual-grading-characteristics-analysis
#7
Greg M Osgood, Gaurav K Thawait, Nima Hafezi-Nejad, Delaram Shakoor, Adam Shaner, John Yorkston, Wojciech B Zbijewski, Jeffrey H Siewerdsen, Shadpour Demehri
OBJECTIVES: To evaluate image quality and inter-observer reliability of novel Cone Beam CT (CBCT) scanner in comparison with plain radiography for assessment of fracture healing in presence of metal hardware. METHODS: In this prospective IRB approved HIPAA complaint study, written informed consent was obtained from 27 patients (10 females; 17 males, mean age 44 years, age range 21- 83 years) with either upper or lower extremity fracture, and with metal hardware, who underwent CBCT scans and had a clinical radiograph of the affected part...
March 10, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28278002/quantifying-abdominal-adipose-tissue-and-thigh-muscle-volume-and-hepatic-proton-density-fat-fraction-repeatability-and-accuracy-of-an-mr-imaging-based-semiautomated-analysis-method
#8
Michael S Middleton, William Haufe, Jonathan Hooker, Magnus Borga, Olof Dahlqvist Leinhard, Thobias Romu, Patrik Tunón, Gavin Hamilton, Tanya Wolfson, Anthony Gamst, Rohit Loomba, Claude B Sirlin
Purpose To determine the repeatability and accuracy of a commercially available magnetic resonance (MR) imaging-based, semiautomated method to quantify abdominal adipose tissue and thigh muscle volume and hepatic proton density fat fraction (PDFF). Materials and Methods This prospective study was institutional review board- approved and HIPAA compliant. All subjects provided written informed consent. Inclusion criteria were age of 18 years or older and willingness to participate. The exclusion criterion was contraindication to MR imaging...
March 9, 2017: Radiology
https://www.readbyqxmd.com/read/28265706/type-1-papillary-renal-cell-carcinoma-differentiation-from-type-2-papillary-rcc-on-multiphasic-mdct
#9
Jonathan R Young, Heidi Coy, Michael Douek, Pechin Lo, James Sayre, Allan J Pantuck, Steven S Raman
PURPOSE: To investigate whether multiphasic MDCT enhancement can help differentiate type 1 papillary renal cell carcinoma (RCC) from type 2 papillary RCC. METHODS: With IRB approval for this HIPAA-compliant retrospective study, we derived a cohort of 36 type 1 papillary RCCs and 33 type 2 papillary RCCs with preoperative multiphasic MDCT with up to four phases (unenhanced, corticomedullary, nephrographic, and excretory) from 2000 to 2013. Following segmentation, a computer-assisted detection (CAD) algorithm selected a 0...
March 7, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28258904/a-simplified-approach-to-encephalitis-and-its-mimics-key-clinical-decision-points-in-the-setting-of-specific-imaging-abnormalities
#10
Colin D McKnight, Aine M Kelly, Myria Petrou, Anna E Nidecker, Matthew T Lorincz, Duaa K Altaee, Stephen S Gebarski, Bradley Foerster
RATIONALE AND OBJECTIVES: Infectious encephalitis is a relatively common cause of morbidity and mortality. Treatment of infectious encephalitis with antiviral medication can be highly effective when administered promptly. Clinical mimics of encephalitis arise from a broad range of pathologic processes, including toxic, metabolic, neoplastic, autoimmune, and cardiovascular etiologies. These mimics need to be rapidly differentiated from infectious encephalitis to appropriately manage the correct etiology; however, the many overlapping signs of these various entities present a challenge to accurate diagnosis...
February 28, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28257467/diagnostic-features-of-quantitative-comb-push-shear-elastography-for-breast-lesion-differentiation
#11
Mahdi Bayat, Max Denis, Adriana Gregory, Mohammad Mehrmohammadi, Viksit Kumar, Duane Meixner, Robert T Fazzio, Mostafa Fatemi, Azra Alizad
BACKGROUND: Lesion stiffness measured by shear wave elastography has shown to effectively separate benign from malignant breast masses. The aim of this study was to evaluate different aspects of Comb-push Ultrasound Shear Elastography (CUSE) performance in differentiating breast masses. METHODS: With written signed informed consent, this HIPAA- compliant, IRB approved prospective study included patients from April 2014 through August 2016 with breast masses identified on conventional imaging...
2017: PloS One
https://www.readbyqxmd.com/read/28247870/teledermatology-in-the-inpatient-setting
#12
Rechelle Tull, Karolyn A Wanat
Teledermatology (TD) is a health care delivery modality that uses telecommunication technology to provide dermatologic care. It has grown to be a reliable and diagnostically accurate means of producing quality care while increasing access and reducing wait times in the outpatient setting. In the inpatient setting, TD may be an effective method to improve access to dermatologic care by remotely triaging, assisting, or providing dermatologic consultative services. For inpatient dermatology, there is the potential for TD to increase access to care in the community setting where dermatologists have full outpatient schedules...
March 2017: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28221241/hyperpolarized-helium-3-diffusion-weighted-magnetic-resonance-imaging-detects-abnormalities-of-lung-structure-in-children-with-bronchopulmonary-dysplasia
#13
Lucia Flors, John P Mugler, Alix Paget-Brown, Deborah K Froh, Eduard E de Lange, James T Patrie, Talissa A Altes
PURPOSE: The aim of the study was to determine whether hyperpolarized He diffusion-weighted magnetic resonance imaging detects abnormalities in the lungs in children with bronchopulmonary dysplasia (BPD) as compared with age-matched normal children. MATERIALS AND METHODS: All experiments were compliant with Health Insurance Portability and Accountability Act (HIPAA) and performed with Food and Drug Administration approval under an IND application. The protocol was approved by our Institutional Review Board, and written informed consent was obtained...
February 17, 2017: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/28221096/clinical-performance-of-synthesized-two-dimensional-mammography-combined-with-tomosynthesis-in-a-large-screening-population
#14
Mireille P Aujero, Sara C Gavenonis, Ron Benjamin, Zugui Zhang, Jacqueline S Holt
Purpose To compare the clinical performance of synthesized two-dimensional (s2D) mammography combined with digital breast tomosynthesis (DBT) with that of full-field digital mammography (FFDM) alone and FFDM combined with DBT in a large community-based screening population by analyzing recall rate, positive predictive value, and cancer detection rate. Materials and Methods This was a retrospective study approved by the institutional review board and was HIPAA compliant with waiver of informed consent. A total of 78 810 screening mammograms from October 11, 2011, to June 30, 2016, were retrospectively collected...
April 2017: Radiology
https://www.readbyqxmd.com/read/28212059/pediatric-chest-ct-diagnostic-reference-ranges-development-and-application
#15
Keith J Strauss, Marilyn J Goske, Alexander J Towbin, Debapriya Sengupta, Michael J Callahan, Kassa Darge, Daniel J Podberesky, Donald P Frush, Charles Maxfield, Sjirk J Westra, Jeffrey S Prince, Huimin Wu, Mythreyi Bhargavan-Chatfield
Purpose To determine diagnostic reference ranges on the basis of the size of a pediatric patient's chest and to develop a method to estimate computed tomographic (CT) scanner-specific mean size-specific dose estimates (SSDEs) as a function of patient size and the radiation output of each CT scanner at a site. Materials and Methods The institutional review boards of each center approved this retrospective, HIPAA-compliant, multicenter study; informed consent was waived. CT dose indexes (SSDE, volume CT dose index, and dose length product) of 518 pediatric patients (mean age, 9...
February 17, 2017: Radiology
https://www.readbyqxmd.com/read/28212052/proton-density-fat-fraction-measurements-at-1-5-and-3-t-hepatic-mr-imaging-same-day-agreement-among-readers-and-across-two-imager-manufacturers
#16
Suraj D Serai, Jonathan R Dillman, Andrew T Trout
Purpose To determine the agreement of proton density fat fraction (PDFF) measurements obtained with hepatic magnetic resonance (MR) imaging among readers, imager manufacturers, and field strengths. Materials and Methods This HIPAA-compliant study was approved by the institutional review board. After providing informed consent, 24 adult volunteers underwent imaging with one 1.5-T MR unit (Ingenia; Philips Healthcare, Best, the Netherlands) and two different 3.0-T units (750 W [GE Healthcare, Waukesha, Wis] and Ingenia) on the same day to estimate hepatic PDFF...
February 17, 2017: Radiology
https://www.readbyqxmd.com/read/28212051/-99m-tc-mag3-image-wisely
#17
Andrew T Taylor, Russell D Folks, A K M Fazlur Rahman, Aruna Polsani, Eva V Dubovsky, Raghuveer Halkar, Amita Manatunga
Purpose To determine if commonly administered doses of technetium 99m ((99m)Tc) mertiatide (MAG3) in the range of 300-370 MBq (approximately 8-10 mCi) contribute to image interpretation and justify the resulting radiation exposure. Materials and Methods The respective institutional review boards approved this HIPAA-compliant study and waived informed consent. Baseline and furosemide (99m)Tc-MAG3 imaging examinations in 50 patients suspected of having renal obstruction and 48 patients suspected of having renovascular hypertension (RVH) were randomly selected from archived databases and were independently scored by three experienced readers without access to 2-second flow images...
February 17, 2017: Radiology
https://www.readbyqxmd.com/read/28206962/pi3k-pathway-mutations-are-associated-with-longer-time-to-local-progression-after-radioembolization-of-colorectal-liver-metastases
#18
Etay Ziv, Michael Bergen, Hooman Yarmohammadi, F Ed Boas, E Nadia Petre, Constantinos T Sofocleous, Rona Yaeger, David B Solit, Stephen B Solomon, Joseph P Erinjeri
PURPOSE: To establish the relationship between common mutations in the MAPK and PI3K signaling pathways and local progression after radioembolization. MATERIALS AND METHODS: Retrospective review of a HIPAA-compliant institutional review-board approved database identified 40 patients with chemo-refractory colorectal liver metastases treated with radioembolization who underwent tumor genotyping for hotspot mutations in 6 key genes in the MAPK/PI3K pathways (KRAS, NRAS, BRAF, MEK1, PIK3CA, and AKT1)...
February 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28193464/igas-a-framework-for-using-electronic-intraoperative-medical-records-for-genomic-discovery
#19
Matthew A Levin, Thomas T Joseph, Janina M Jeff, Rajiv Nadukuru, Stephen B Ellis, Erwin P Bottinger, Eimear E Kenny
OBJECTIVE: Design and implement a HIPAA and Integrating the Healthcare Enterprise (IHE) profile compliant automated pipeline, the integrated Genomics Anesthesia System (iGAS), linking genomic data from the Mount Sinai Health System (MSHS) BioMe biobank to electronic anesthesia records, including physiological data collected during the perioperative period. The resulting repository of multi-dimensional data can be used for precision medicine analysis of physiological readouts, acute medical conditions, and adverse events that can occur during surgery...
February 10, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28187264/development-of-a-combined-mr-fingerprinting-and-diffusion-examination-for-prostate-cancer
#20
Alice C Yu, Chaitra Badve, Lee E Ponsky, Shivani Pahwa, Sara Dastmalchian, Matthew Rogers, Yun Jiang, Seunghee Margevicius, Mark Schluchter, William Tabayoyong, Robert Abouassaly, Debra McGivney, Mark A Griswold, Vikas Gulani
Purpose To develop and evaluate an examination consisting of magnetic resonance (MR) fingerprinting-based T1, T2, and standard apparent diffusion coefficient (ADC) mapping for multiparametric characterization of prostate disease. Materials and Methods This institutional review board-approved, HIPAA-compliant retrospective study of prospectively collected data included 140 patients suspected of having prostate cancer. T1 and T2 mapping was performed with fast imaging with steady-state precession-based MR fingerprinting with ADC mapping...
February 10, 2017: Radiology
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