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https://www.readbyqxmd.com/read/28079289/apocrine-metaplasia-found-at-mr-biopsy-is-there-something-to-be-learned
#1
Yiming Gao, Vandana Dialani, Carolynn DeBenedectis, Nicole Johnson, Elena Brachtel, Priscilla Slanetz
The purpose of this study was to determine (a) the frequency of apocrine metaplasia (ApoM) found on MR core biopsy of suspicious findings, and (b) to determine if there are specific MR imaging features that might obviate the need for biopsy. This HIPAA-compliant retrospective study was performed under IRB exemption for quality assurance studies. Patient demographics, MR imaging features, and pathology were reviewed. Breast lesions which underwent MR-guided biopsy, yielding ApoM on pathology analysis were included...
January 12, 2017: Breast Journal
https://www.readbyqxmd.com/read/28076721/effect-of-tumor-complexity-and-technique-on-efficacy-and-complications-after-percutaneous-microwave-ablation-of-stage-t1a-renal-cell-carcinoma-a-single-center-retrospective-study
#2
Marki E Klapperich, E Jason Abel, Timothy J Ziemlewicz, Sara Best, Meghan G Lubner, Stephen Y Nakada, J Louis Hinshaw, Christopher L Brace, Fred T Lee, Shane A Wells
Purpose To evaluate the effects of tumor complexity and technique on early and midterm oncologic efficacy and rate of complications for 100 consecutive biopsy-proved stage T1a renal cell carcinomas (RCCs) treated with percutaneous microwave ablation. Materials and Methods This HIPAA-compliant, single-center retrospective study was approved by the institutional review board. The requirement to obtain informed consent was waived. Ninety-six consecutive patients (68 men, 28 women; mean age, 66 years ± 9.4) with 100 stage T1a N0M0 biopsy-proved RCCs (median diameter, 2...
January 11, 2017: Radiology
https://www.readbyqxmd.com/read/28064345/osseous-metastases-of-chordoma-imaging-and-clinical-findings
#3
Connie Chang, Ivan Chebib, Martin Torriani, Miriam Bredella
PURPOSE: To describe the imaging and clinical characteristics of chordoma osseous metastases (COM). MATERIALS AND METHODS: Our study was IRB approved and HIPAA compliant. A retrospective search of our pathology database for pathology-proven COM yielded 15 patients who had undergone MRI, CT, bone scan, and/or FDG-PET/CT. The imaging and clinical features of the COMs were recorded. A control group of age and gender matched chordoma patients without osseous metastasis was evaluated...
January 7, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28063601/bone-marrow-fat-content-is-correlated-with-hepatic-fat-content-in-paediatric-non-alcoholic-fatty-liver-disease
#4
N Y Yu, T Wolfson, M S Middleton, G Hamilton, A Gamst, J E Angeles, J B Schwimmer, C B Sirlin
AIM: To investigate the relationship between bone marrow fat content and hepatic fat content in children with known or suspected non-alcoholic fatty liver disease (NAFLD). MATERIALS AND METHODS: This was an institutional review board-approved, Health Insurance Portability and Accountability Act (HIPAA)-compliant, cross-sectional, prospective analysis of data collected between October 2010 to March 2013 in 125 children with known or suspected NAFLD. Written informed consent was obtained for same-day research magnetic resonance imaging (MRI) of the lumbar spine, liver, and abdominal adiposity...
January 4, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28058550/do-calcifications-seen-on-mammography-after-neoadjuvant-chemotherapy-for-breast-cancer-always-need-to-be-excised
#5
Yara Feliciano, Anita Mamtani, Monica Morrow, Michelle M Stempel, Sujata Patil, Maxine S Jochelson
BACKGROUND: This study aimed to determine the relationship between mammographic calcifications and magnetic resonance imaging (MRI) tumoral enhancement before and after neoadjuvant chemotherapy (NAC) and to assess the impact of these findings on surgical management. METHODS: This Institutional Review Board-approved, Health Insurance Portability and Accountability Act (HIPAA)-compliant retrospective study involved breast cancer patients who underwent NAC between 2009 and 2015...
January 5, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28054731/lung-adenocarcinoma-assessment-of-epidermal-growth-factor-receptor-mutation-status-based-on-extended-models-of-diffusion-weighted-image
#6
Mei Yuan, Xue-Hui Pu, Xiao-Quan Xu, Yu-Dong Zhang, Yan Zhong, Hai Li, Jiang-Fen Wu, Tong-Fu Yu
PURPOSE: To evaluate the diagnostic performance of extended models of diffusion-weighted (DW) imaging to help differentiate the epidermal growth factor receptor (EGFR) mutation status in stage IIIA-IV lung adenocarcinoma. MATERIALS AND METHODS: This retrospective study had institutional research board approval and was HIPAA compliant. Preoperative extended DW imaging including intravoxel incoherent motion (IVIM) and diffusional kurtosis imaging (DKI) 3 Tesla MRI were retrospectively evaluated in 53 patients with pathologically confirmed non-early stage (IIIA-IV) lung adenocarcinoma...
January 5, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28051912/utility-of-pet-ct-to-evaluate-retroperitoneal-lymph-node-metastasis-in-high-risk-endometrial-cancer-results-of-acrin-6671-gog-0233-trial
#7
Mostafa Atri, Zheng Zhang, Farrokh Dehdashti, Susanna I Lee, Helga Marques, Shamshad Ali, Wui-Jin Koh, Robert S Mannel, Paul DiSilvestro, Stephanie A King, Michael Pearl, XunClare Zhou, Marie Plante, Katherine M Moxley, Michael Gold
Purpose To assess the diagnostic accuracy of fluorine 18 fluorodeoxyglucose (FDG) positron emission tomography (PET) combined with diagnostic contrast material-enhanced computed tomography (CT) in detecting lymph node (LN) metastasis in high-risk endometrial cancer. Materials and Methods This prospective multicenter HIPAA-compliant study had institutional review board approval, and all participants gave written informed consent. Data were accrued between January 2010 and June 2013. Patients underwent PET/CT and pelvic and abdominal lymphadenectomy...
January 3, 2017: Radiology
https://www.readbyqxmd.com/read/28051911/quantification-of-human-cortical-bone-bound-and-free-water-in-vivo-with-ultrashort-echo-time-mr-imaging-a-model-based-approach
#8
Shahrokh Abbasi-Rad, Hamidreza Saligheh Rad
Purpose To quantify free and bound water components of cortical bone with a model-based numeric approach with use of ultrashort echo time (UTE) magnetic resonance (MR) imaging in vivo in order to introduce a new predictor for age-related deterioration of cortical bone structure. Materials and Methods Human studies were compliant with HIPAA and approved by the institutional review board. Dual-repetition time three-dimensional hybrid-radial UTE imaging was performed, followed by the application of postprocessing algorithms, to quantify free and bound water parameters (concentration [ρ] and longitudinal relaxation time [T1]) of human cortical bone in vivo...
January 4, 2017: Radiology
https://www.readbyqxmd.com/read/28050658/development-of-a-searchable-database-of-cryoablation-simulations-for-use-in-treatment-planning
#9
F Edward Boas, Govindarajan Srimathveeravalli, Jeremy C Durack, Elena A Kaye, Joseph P Erinjeri, Etay Ziv, Majid Maybody, Hooman Yarmohammadi, Stephen B Solomon
PURPOSE: To create and validate a planning tool for multiple-probe cryoablation, using simulations of ice ball size and shape for various ablation probe configurations, ablation times, and types of tissue ablated. MATERIALS AND METHODS: Ice ball size and shape was simulated using the Pennes bioheat equation. Five thousand six hundred and seventy different cryoablation procedures were simulated, using 1-6 cryoablation probes and 1-2 cm spacing between probes. The resulting ice ball was measured along three perpendicular axes and recorded in a database...
January 3, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28048384/su-d-207b-06-predicting-breast-cancer-malignancy-on-dce-mri-data-using-pre-trained-convolutional-neural-networks
#10
N Antropova, B Huynh, M Giger
PURPOSE: We investigate deep learning in the task of distinguishing between malignant and benign breast lesions on dynamic contrast-enhanced MR images (DCE-MRIs), eliminating the need for lesion segmentation and extraction of tumor features. We evaluate convolutional neural network (CNN) after transfer learning with ImageNet, a database of thousands of non-medical images. METHODS: Under a HIPAA-compliant IRB protocol, a database of 551 (357 malignant and 194 benign) breast MRI cases was collected...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047907/th-ab-207a-03-skin-dose-to-patients-receiving-multiple-cta-and-ct-exams-of-the-head
#11
R D Nawfel, G Young
PURPOSE: To measure patient skin dose from CT angiography (CTA) and CT exams of the head, and determine if patients having multiple exams could receive cumulative doses that approach or exceed deterministic thresholds. METHODS: This study was HIPAA compliant and conducted with IRB approval. Patient skin doses were measured over a 4 month period using nanoDot OSL dosimeters placed on the head of 52 patients for two CT scanners. On each scanner, 26 patients received CT exams (scanner 1: 10 females, 16 males, mean age 64...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28040687/de-identification-of-patient-notes-with-recurrent-neural-networks
#12
Franck Dernoncourt, Ji Young Lee, Ozlem Uzuner, Peter Szolovits
OBJECTIVE: Patient notes in electronic health records (EHRs) may contain critical information for medical investigations. However, the vast majority of medical investigators can only access de-identified notes, in order to protect the confidentiality of patients. In the United States, the Health Insurance Portability and Accountability Act (HIPAA) defines 18 types of protected health information that needs to be removed to de-identify patient notes. Manual de-identification is impractical given the size of electronic health record databases, the limited number of researchers with access to non-de-identified notes, and the frequent mistakes of human annotators...
December 30, 2016: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/28029703/the-sonographic-stenosis-index-a-new-specific-quantitative-measure-of-transplant-hepatic-arterial-stenosis
#13
Thomas X Le, Daniel S Hippe, Michael F McNeeley, Manjiri K Dighe, Theodore J Dubinsky, Sherwin S Chan
OBJECTIVES: This study evaluates the sensitivity and specificity of stenosis index (SI), which accounts for the entire spectral Doppler waveform, to detect significant transplant hepatic arterial stenosis. MATERIALS AND METHODS: In this institutional review board-approved, HIPAA compliant study, we retrospectively analyzed 69 patients who had catheter angiography for suspected transplant hepatic arterial stenosis (THAS) between January 2006 and December 2010; all patients had Doppler ultrasound within 30 days before angiography...
December 28, 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28027742/prognostic-value-of-ct-derived-left-atrial-and-left-ventricular-measures-in-patients-with-acute-chest-pain
#14
Richard A P Takx, Rozemarijn Vliegenthart, U Joseph Schoepf, John W Nance, Fabian Bamberg, Joseph A Abro, Christine M Carr, Sheldon E Litwin, Paul Apfaltrer
PURPOSE: To determine which left atrial (LA) and left ventricular (LV) parameters are associated with future major adverse cardiac event (MACE) and whether these measurements have independent prognostic value beyond risk factors and computed tomography (CT)-derived coronary artery disease measures. MATERIALS AND METHODS: This retrospective analysis was performed under an IRB waiver and in HIPAA compliance. Subjects underwent coronary CT angiography (CCTA) using a dual-source CT system for acute chest pain evaluation...
January 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28017270/effect-of-fixed-volume-and-weight-based-dosing-regimens-on-the-cost-and-volume-of-administered-iodinated-contrast-material-at-abdominal-ct
#15
Matthew S Davenport, Kushal R Parikh, William W Mayo-Smith, Gary M Israel, Richard K J Brown, James H Ellis
PURPOSE: To determine the magnitude of subject-level and population-level cost savings that could be realized by moving from fixed-volume low-osmolality iodinated contrast material administration to an effective weight-based dosing regimen for contrast-enhanced abdominopelvic CT. METHODS: HIPAA-compliant, institutional review board-exempt retrospective cohort study of 6,737 subjects undergoing contrast-enhanced abdominopelvic CT from 2014 to 2015. Subject height, weight, lean body weight (LBW), and body surface area (BSA) were determined...
December 21, 2016: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28007583/towards-a-privacy-preserving-cohort-discovery-framework-for-clinical-research-networks
#16
Jiawei Yuan, Bradley Malin, François Modave, Yi Guo, William R Hogan, Elizabeth Shenkman, Jiang Bian
BACKGROUND: The last few years have witnessed an increasing number of clinical research networks (CRNs) focused on building large collections of data from electronic health records (EHRs), claims, and patient-reported outcomes (PROs). Many of these CRNs provide a service for the discovery of research cohorts with various health conditions, which is especially useful for rare diseases. Supporting patient privacy can enhance the scalability and efficiency of such processes; however, current practice mainly relies on policy, such as guidelines defined in the Health Insurance Portability and Accountability Act (HIPAA), which are insufficient for CRNs (e...
December 19, 2016: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28005489/mr-neurography-of-brachial-plexus-at-3-0-t-with-robust-fat-and-blood-suppression
#17
Xinzeng Wang, Crystal Harrison, Yogesh K Mariappan, Karthik Gopalakrishnan, Avneesh Chhabra, Robert E Lenkinski, Ananth J Madhuranthakam
Purpose To develop and evaluate magnetic resonance (MR) neurography of the brachial plexus with robust fat and blood suppression for increased conspicuity of nerves at 3.0 T in clinically feasible acquisition times. Materials and Methods This prospective study was HIPAA compliant, with institutional review board approval and written informed consent. A low-refocusing-flip-angle three-dimensional (3D) turbo spin-echo (TSE) sequence was modified to acquire both in-phase and out-of-phase echoes, required for chemical shift (Dixon) reconstruction, in the same repetition by using partial echoes combined with modified homodyne reconstruction with phase preservation...
December 22, 2016: Radiology
https://www.readbyqxmd.com/read/28004326/utility-of-mdct-findings-in-predicting-patient-management-outcomes-in-renal-trauma
#18
Arthur H Baghdanian, Armonde A Baghdanian, Anthony Armetta, Richard K Babayan, Christina A LeBedis, Jorge A Soto, Stephan W Anderson
PURPOSE: The purpose of this study is to assess the utility of computed tomography (CT) in predicting clinical outcomes in renal trauma. MATERIALS/METHODS: This retrospective study was IRB approved and HIPAA compliant; informed consent was waived. One-hundred-sixty-two, trauma-related renal injuries (157 adults) from January 01, 2006 to December 31, 2013 were included in this retrospective study. CT findings of vascular and collecting system (CS) injuries were recorded, and American Association for the Surgery of Trauma (AAST) renal injury grades were assigned...
December 21, 2016: Emergency Radiology
https://www.readbyqxmd.com/read/27981651/mr-spectroscopy-of-breast-cancer-for-assessing-early-treatment-response-results-from-the-acrin-6657-mrs-trial
#19
Patrick J Bolan, Eunhee Kim, Benjamin A Herman, Gillian M Newstead, Mark A Rosen, Mitchell D Schnall, Etta D Pisano, Paul T Weatherall, Elizabeth A Morris, Constance D Lehman, Michael Garwood, Michael T Nelson, Douglas Yee, Sandra M Polin, Laura J Esserman, Constantine A Gatsonis, Gregory J Metzger, David C Newitt, Savannah C Partridge, Nola M Hylton
PURPOSE: To estimate the accuracy of predicting response to neoadjuvant chemotherapy (NACT) in patients with locally advanced breast cancer using MR spectroscopy (MRS) measurements made very early in treatment. MATERIALS AND METHODS: This prospective Health Insurance Portability and Accountability Act (HIPAA)-compliant protocol was approved by the American College of Radiology and local-site institutional review boards. One hundred nineteen women with invasive breast cancer of ≥3 cm undergoing NACT were enrolled between September 2007 and April 2010...
December 16, 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/27977329/reducing-artifacts-during-arterial-phase-of-gadoxetate-disodium-enhanced-mr-imaging-dilution-method-versus-reduced-injection-rate
#20
Young Kon Kim, Wei-Chan Lin, Kyunghyun Sung, Steven S Raman, Daniel Margolis, Yaeji Lim, Seonhye Gu, David Lu
Purpose To compare two contrast material-administration protocols (dilution vs slow injection) in terms of their effectiveness in arterial phase artifact reduction at gadoxetic acid-enhanced magnetic resonance (MR) imaging. Materials and Methods This HIPAA-compliant retrospective case-controlled cohort study was approved by the institutional review board, with a waiver of informed patient consent. A total of 318 consecutive patients undergoing gadoxetic acid-enhanced MR imaging were placed into one of two subcohorts of 159 consecutive patients each: the dilution subcohort (gadoxetic acid was diluted 1:1 with saline and injected at a rate of 2...
December 15, 2016: Radiology
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