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https://www.readbyqxmd.com/read/29241086/practical-aspects-of-the-automated-preparation-of-aqueous-two-phase-systems-for-the-analysis-of-biological-macromolecules
#1
Rana Hameed, Jonathan Huddleston, Svetlana Ignatova
A robust strategy for the automated preparation of aqueous two-phase systems (ATPS) using a liquid handling sample processor was developed using gravimetric methods: to determine the accuracy of preparation. The major robotic control parameters requiring adjustment were; speed of aspiration and dispense; delay times following aspiration and dispense alongside measures to control cross-contamination during phase sampling. In general mixture compositions of both polymer/polymer and polymer/salt mixtures could be prepared with a target bias accuracy of less than 5%...
October 3, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29241058/a-novel-robotic-arm-driven-by-sandwich-piezoelectric-transducers
#2
Zheng Jiang, Liang Wang, Jiamei Jin
In this work, a novel robotic arm driven by sandwich piezoelectric transducers is proposed. The proposed robotic arm is composed of three arms and four joints. Each arm consists of a sandwich piezoelectric transducer and an H-shaped hollow frame. The sandwich piezoelectric transducer utilizes frictional force to drive the joints on its both sides to rotate simultaneously. The joint between two arms can be driven to rotate in two perpendicular directions by two sandwich piezoelectric transducers. The rotation of joints results in the arm motion...
December 2, 2017: Ultrasonics
https://www.readbyqxmd.com/read/29240876/machine-learning-for-classifying-tuberculosis-drug-resistance-from-dna-sequencing-data
#3
Yang Yang, Katherine E Niehaus, Timothy M Walker, Zamin Iqbal, A Sarah Walker, Daniel J Wilson, Tim E Peto, Derrick W Crook, E Grace Smith, Tingting Zhu, David A Clifton
Motivation: Correct and rapid determination of Mycobacterium tuberculosis (MTB) resistance against available tuberculosis (TB) drugs is essential for the control and management of TB. Conventional molecular diagnostic test assumes that the presence of any well-studied single nucleotide polymorphisms is sufficient to cause resistance, which yields low sensitivity for resistance classification. Methods: Given the availability of DNA sequencing data from MTB, we developed machine learning models for a cohort of 1839 UK bacterial isolates to classify MTB resistance against eight anti-TB drugs (isoniazid, rifampicin, ethambutol, pyrazinamide, ciprofloxacin, moxifloxacin, ofloxacin, streptomycin) and to classify multi-drug resistance...
December 12, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29240281/comparative-analysis-of-2-robotic-thyroidectomy-procedures-transoral-versus-bilateral-axillo-breast-approach
#4
Young Jun Chai, Hoon Yub Kim, Hong Kyu Kim, Sang Ho Jun, Gianlorenzo Dionigi, Angkoon Anuwong, Jeremy D Richmon, Ralph P Tufano
BACKGROUND: The surgical outcomes of a single surgeon's initial cases of transoral robotic thyroidectomy (TORT) were compared with the surgeon's initial cases of a bilateral axillo-breast approach (BABA) robotic thyroidectomy. METHODS: The medical reports were retrospectively reviewed. The BABA robotic thyroidectomies were performed between 2008 and 2009, and TORTs were performed between 2012 and 2016. RESULTS: Each group comprised 50 patients...
December 14, 2017: Head & Neck
https://www.readbyqxmd.com/read/29239992/comparison-of-resistance-based-walking-cardiorespiratory-test-to-the-bruce-protocol
#5
Christopher P Hurt, Marcas Bamman, Avantika Naidu, David A Brown
Cardiorespiratory fitness is assessed through graded exercise tests that determine the maximum amount of sustained mechanical work that an individual can perform while also providing health and fitness related information. This manuscript describes a novel method to perform graded exercise tests that uses posteriorly directed resistive forces. The purpose of this investigation is to validate a novel resistance based test in comparison to a traditional speed and incline based test in a cohort of non-impaired individuals...
December 11, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29239095/structural-and-conformational-chemistry-from-electrochemical-molecular-machines-replicating-biological-functions-a-review
#6
REVIEW
Toribio F Otero
Each constitutive chain of a conducting polymer electrode acts as a reversible multi-step electrochemical molecular motor: reversible reactions drive reversible conformational movements of the chain. The reaction-driven cooperative actuation of those molecular machines generates, or destroys, inside the film the free volume required to lodge/expel balancing counterions and solvent: reactions drive reversible film volume variations, which basic structural components are here identified and quantified from electrochemical responses...
December 14, 2017: Chemical Record: An Official Publication of the Chemical Society of Japan ... [et Al.]
https://www.readbyqxmd.com/read/29239049/a-new-3d-printing-strategy-by-harnessing-deformation-instability-and-fracture-of-viscoelastic-inks
#7
Hyunwoo Yuk, Xuanhe Zhao
Direct ink writing (DIW) has demonstrated great potential as a multimaterial multifunctional fabrication method in areas as diverse as electronics, structural materials, tissue engineering, and soft robotics. During DIW, viscoelastic inks are extruded out of a 3D printer's nozzle as printed fibers, which are deposited into patterns when the nozzle moves. Hence, the resolution of printed fibers is commonly limited by the nozzle's diameter, and the printed pattern is limited by the motion paths. These limits have severely hampered innovations and applications of DIW 3D printing...
December 14, 2017: Advanced Materials
https://www.readbyqxmd.com/read/29238636/functional-outcome-of-neurologic-controlled-hal-exoskeletal-neurorehabilitation-in-chronic-spinal-cord-injury-a-pilot-with-one-year-treatment-and-variable-treatment-frequency
#8
Oliver Jansen, Thomas A Schildhauer, Renate C Meindl, Martin Tegenthoff, Peter Schwenkreis, Matthias Sczesny-Kaiser, Dennis Grasmücke, Christian Fisahn, Mirko Aach
Study Design: Longitudinal prospective study. Objectives: Whether 1-year HAL-BWSTT of chronic spinal cord injured patients can improve independent ambulated mobility further as a function of training frequency, after an initial 3-month training period. Methods: Eight patients with chronic SCI were enrolled. They initially received full standard physical therapy and neurorehabilitation in the acute/subacute posttrauma phase. During this trial, all patients first underwent a daily (5 per week) HAL-BWSTT for 12 weeks...
December 2017: Global Spine Journal
https://www.readbyqxmd.com/read/29238155/postoperative-pain-after-single-site-versus-multiport-hysterectomy
#9
Chris Kliethermes, Kelly Blazek, Kausar Ali, J Biba Nijjar, Stephanie Kliethermes, Xiaoming Guan
Background and Objectives: With advances in laparoscopic surgery, the goal of surgeons and patients is to minimize pain to allow for faster recovery and return to normal daily activities. One of these advances is single-site surgery. In this study, we compared postoperative pain in laparoendoscopic single-site surgery (LESS) to that in traditional multiple-incision hysterectomy. Methods: Seventy patients were selected for this prospective cohort study, with 35 undergoing multiple-incision and 35 undergoing LESS hysterectomy...
October 2017: JSLS: Journal of the Society of Laparoendoscopic Surgeons
https://www.readbyqxmd.com/read/29238153/risk-factors-for-open-conversion-in-minimally-invasive-cholecystectomy
#10
Antonio Gangemi, Richard Danilkowicz, Francesco Bianco, Mario Masrur, Pier Cristoforo Giulianotti
Background and Objectives: Open conversion (OC) occurs in 5 to 10% of laparoscopic cholecystectomies (LCs) and results in suboptimal outcomes. Herein, we report our experience with OC in cholecystectomy performed with the minimally invasive (MIS) approach. Methods: Data from 960 minimally invasive cholecystectomies performed in the University of Illinois at Chicago (UIC) Division of General, Minimally Invasive, and Robotic Surgery were retrospectively compiled. Patient demographics and outcomes were analyzed for the major indicators that may predispose to OC...
October 2017: JSLS: Journal of the Society of Laparoendoscopic Surgeons
https://www.readbyqxmd.com/read/29237220/-new-approaches-for-young-surgeons-students-symposium-on-minimally-invasive-surgery
#11
Paul Jonathan Roch, Mirco Friedrich, Karl-Friedrich Kowalewski, Mona Wanda Schmidt, Javier De la Garza Herrera, Philip Christoph Müller, Laura Benner, Philipp Romero, Beat Peter Müller-Stich, Felix Nickel
Background Physician shortage is particularly striking in surgical specialities. Umbrella organisations are making an effort to recruit medical students. Students' symposia during congresses seem to provide a promising approach to developing motivation and promoting interest. An exemplary students' symposium took place at the three nations meeting for minimally invasive surgery (MIS). Our aim was to evaluate the students' symposium from the students' perspective, in order to give recommendations for the future...
December 2017: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/29236304/enterovirus-detection-in-patients-with-acute-gastroenteritis-in-switzerland
#12
Rainer Gosert, Ulrich Heininger, Hans H Hirsch
Acute gastroenteritis (GE) has a major impact on morbidity and mortality worldwide, yet comprehensive data regarding infectious agents including enteroviruses are scarce. We hypothesized that enteroviruses constitute a significant cause of acute GE. We analyzed 677 stool samples from 504 patients, which had been submitted for suspected infectious GE. 0.2 ml of stool suspension was extracted using the Abbott m2000 sp robot and analysed by multiplex nucleic acid testing (NAT) using the Luminex xTAG gastrointestinal pathogen panel (GPP) as well as by specific NATs detecting enteroviruses and polioviruses...
December 13, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/29236300/creepiness-creeps-in-uncanny-valley-feelings-are-acquired-in-childhood
#13
Kimberly A Brink, Kurt Gray, Henry M Wellman
The uncanny valley posits that very human-like robots are unsettling, a phenomenon amply demonstrated in adults but unexplored in children. Two hundred forty 3- to 18-year-olds viewed one of two robots (machine-like or very human-like) and rated their feelings toward (e.g., "Does the robot make you feel weird or happy?") and perceptions of the robot's capacities (e.g., "Does the robot think for itself?"). Like adults, children older than 9 judged the human-like robot as creepier than the machine-like robot-but younger children did not...
December 13, 2017: Child Development
https://www.readbyqxmd.com/read/29235838/hydrogel-with-ultra-fast-self-healing-property-both-in-air-and-underwater
#14
Weipeng Chen, Dezhao Hao, Wanjun Hao, Xinglin Guo, Lei Jiang
Self-healing hydrogels have a great potential utilization in 3D printing, soft robotics, and tissue engineering, due to the ability to expand the useful lifespan. There has been a large number of successful strategies in developing hydrogels which exhibit rapid and autonomous recovery. However, a gel with an excellent self-healing performance within several seconds is still an enormous challenge. Here, an ultra-fast self-healing hydrogel based on a PVA/agarose double network is presented. The gel utilizing dynamic borate bond exhibits 100% cure in strength and elongation after healing for 10 seconds in air, and this hydrogel shows an excellent self-healing property underwater as well...
December 13, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29235521/infrared-actuation-induced-simultaneous-reconfiguration-of-surface-color-and-morphology-for-soft-robotics
#15
Seyedali Banisadr, Jian Chen
Cephalopods, such as cuttlefish, demonstrate remarkable adaptability to the coloration and texture of their surroundings by modulating their skin color and surface morphology simultaneously, for the purpose of adaptive camouflage and signal communication. Inspired by this unique feature of cuttlefish skins, we present a general approach to remote-controlled, smart films that undergo simultaneous changes of surface color and morphology upon infrared (IR) actuation. The smart film has a reconfigurable laminated structure that comprises an IR-responsive nanocomposite actuator layer and a mechanochromic elastomeric photonic crystal layer...
December 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29235355/facile-fabrication-of-electrically-conductive-low-density-polyethylene-carbon-fiber-tubes-for-novel-smart-materials-via-multi-axial-orientation
#16
Yijun Li, Min Nie, Qi Wang
Electromechanical sensors are indispensable components in functional devices and robotics application. However, the fabrication of the sensors still maintain a challenging issue that high percolation threshold and easy failure of conductive network are derived from uniaxial orientation of conductive fillers in practical melt processing. Herein, we reported a facile fabrication method to prepare multi-axial low density polyethylene (LDPE) /carbon fibers (CFs) tube with bidirectional controllable electrical conductivity and sensitive strain-responsive performance via rotation extrusion technology...
December 13, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29232985/outcome-of-robotic-radical-prostatectomy-in-men-over-74
#17
Burkhard Ubrig, Anselm Merklinghaus, Markus Heiland, Alexander Roosen
Introduction We set out to evaluate outcomes in patients over 74 after robotic radical prostatectomy . Material and Methods 647 patients over 74 patients≥75 were analyzed for preoperative factors (BMI,ASA,PSA,IPSS,IIEF), operative and perioperative characteristics (technique,erythrocyte conc.,complications), and histopathological results. After 12 months, following items were assessed: PSA, frequency of urine loss, number of pads used (including safety), incontinence at night and potency as quantified by IIEF-5...
December 12, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/29232764/brain-biopsy-performed-with-the-ronna-g3-system-a-case-study-on-using-a-novel-robotic-navigation-device-for-stereotactic-neurosurgery
#18
Domagoj Dlaka, Marko Švaco, Darko Chudy, Bojan Jerbić, Bojan Šekoranja, Filip Šuligoj, Josip Vidaković, Fadi Almahariq, Dominik Romić
BACKGROUND: Robotic neuronavigation is becoming an important tool for neurosurgeons. We present a case study of a frameless stereotactic biopsy guided by the RONNA G3 robotic neuronavigation system. METHODS: A 45 year-old patient with a history of vertigo, nausea and vomiting was diagnosed with multiple periventricular lesions. Neurological status was unremarkable. A frameless robotic biopsy of a brain lesion was performed. RESULTS: Three tissue samples were obtained...
December 12, 2017: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://www.readbyqxmd.com/read/29232300/three-dimensional-printing-of-life-like-models-for-simulation-and-training-of-minimally-invasive-cardiac-surgery
#19
Toshiyuki Yamada, Motohiko Osako, Tomoya Uchimuro, Ryogen Yoon, Toshiaki Morikawa, Maki Sugimoto, Hisao Suda, Hideyuki Shimizu
OBJECTIVE: As the use of minimally invasive surgery in cardiothoracic surgery increases, so does the need for simulation and training. We developed a heart model for simulation and training of minimally invasive cardiac surgery, particularly minimally invasive mitral valve repair using our new three-dimensional printing system. METHODS: Digital imaging and communication in medicine data from patient computed tomography, three-dimensional computer-aided design, and three-dimensional printing helped create replicas of the heart and thoracic cavity...
December 7, 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29232296/morbid-obesity-does-not-increase-morbidity-or-mortality-in-robotic-cardiac-surgery
#20
Hiroto Kitahara, Brooke Patel, Mackenzie McCrorey, Sarah Nisivaco, Husam H Balkhy
OBJECTIVE: Morbid obesity (body mass index ≥ 35 kg/m) usually confers a higher perioperative risk in cardiac surgery. Robotic cardiac surgery may have many advantages for these high-risk patients. METHODS: We retrospectively reviewed patients undergoing robotic cardiac surgery from July 2013 to April 2017 at our institution. We compared the outcomes of morbidly obese patients versus nonobese patients. RESULTS: A total of 486 patients underwent robotic cardiac surgery (322 men, median age = 65 years)...
December 7, 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
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