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hyperlipidemia and ischemic stroke

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https://www.readbyqxmd.com/read/29325919/patients-with-cerebral-stroke-have-an-increased-risk-of-gastroesophageal-reflux-disease-a-population-based-cohort-study
#1
Chen-Shu Chang, Hsuan-Ju Chen, Chun-Hui Liao
BACKGROUND: Medical complications following stroke often result in significant morbidity. This study was designed to investigate the prevalence and risk of gastroesophageal reflux disease (GERD) between patients with stroke and those without stroke in Taiwan. METHODS AND RESULTS: This retrospective cohort study was conducted using the Taiwan National Health Insurance Research Database. The study included 18,412 patients newly diagnosed as having stroke during 2000-2006 and 18,412 patients without stroke frequency-matched by sex, age, and index year...
January 8, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29284738/comparison-of-risk-factor-control-in-the-year-after-discharge-for-ischemic-stroke-versus-acute-myocardial-infarction
#2
Dawn M Bravata, Joanne Daggy, Jared Brosch, Jason J Sico, Fitsum Baye, Laura J Myers, Christianne L Roumie, Eric Cheng, Jessica Coffing, Greg Arling
BACKGROUND AND PURPOSE: The Veterans Health Administration has engaged in quality improvement to improve vascular risk factor control. We sought to examine blood pressure (<140/90 mm Hg), lipid (LDL [low-density lipoprotein] cholesterol <100 mg/dL), and glycemic control (hemoglobin A1c <9%), in the year post-hospitalization for acute ischemic stroke or acute myocardial infarction (AMI). METHODS: We identified patients who were hospitalized (fiscal year 2011) with ischemic stroke, AMI, congestive heart failure, transient ischemic attack, or pneumonia/chronic obstructive pulmonary disease...
December 28, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29284570/prognosis-of-midlife-stroke
#3
Lynda D Lisabeth, Jonggyu Baek, Lewis B Morgenstern, Darin B Zahuranec, Erin Case, Lesli E Skolarus
OBJECTIVE: To characterize stroke outcomes in a midlife population-based stroke cohort, and to describe comorbidities, quality of care, and risk of recurrence in this age group. MATERIALS AND METHODS: Ischemic strokes (ISs) were identified from the population-based Brain Attack Surveillance in Corpus Christi Project (2000-2012). Data were from medical records and patient interviews. Ninety-day outcomes (functional, neurologic, cognitive, quality of life [QOL]), prevalence of comorbidities, quality of care, and 1-year recurrence were estimated for those aged 45-64 (midlife) and compared with those aged ≥65 using sex and race-ethnicity adjusted regression models...
December 25, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29275418/opium-addiction-and-ischemic-stroke-in-isfahan-iran-a-case-control-study
#4
Homa Ebrahimi, Shaghayegh Haghjoo Javanmard, Sedigheh Asgary, Leila Dehghani, Masoud Amiri, Mohammad Saadatnia
BACKGROUND: The effect of opium addiction (OA) on cerebrovascular disease is controversial. The aim of this study was to clarify this relationship in Iranian patients with ischemic stroke. METHODS: In a case-control study, 672 patients with ischemic stroke and 293 controls without a previous history of cerebrovascular or cardiovascular diseases were compared. OA as well as other risk factors such as diabetes mellitus (DM), hypertension (HTN), hyperlipidemia, tobacco smoking (TS) were compared between the 2 groups...
December 22, 2017: European Neurology
https://www.readbyqxmd.com/read/29201550/dehydration-is-a-strong-predictor-of-long-term-prognosis-of-thrombolysed-patients-with-acute-ischemic-stroke
#5
Sha-Sha Li, Ming-Ming Yin, Zhong-He Zhou, Hui-Sheng Chen
Background and Purpose: Dehydration was found to be involved in the poor prognosis of patients with acute ischemic stroke. It is unclear whether dehydration status before onset is related with prognosis of thrombolysed patients with acute ischemic stroke. If it is the case, quickly hydrating may improve the prognosis. The present study was designed to explore the issue. Methods: Eligible 294 patients with acute ischemic stroke after thrombolysis were enrolled in the present study according to inclusion/exclusion criteria...
November 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29196059/importance-rating-of-risk-factors-of-ischemic-stroke-in-patients-over-85-years-old-in-the-polish-population
#6
REVIEW
Żanna Pastuszak, Ewa Koźniewska, Adam Stępień, Anna Piusińska-Macoch, Zbigniew Czernicki, Waldemar Koszewski
INTRODUCTION: The European population is aging and the number of elderly patients suffering from ischemic brain stroke increases. A better knowledge of the correlation between the risk factors and the course of the disease in old people may be useful for planning medical care and prophylactic strategies. AIM: This prospective study aimed to perform a demographic and clinical analysis of the etiology of ischemic stroke, survival rate and severity of post-stroke disability in patients who developed ischemic stroke at the age of over 85 years in the Polish population...
November 16, 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/29184342/risk-factors-vascular-lesion-distribution-outcome-and-recurrence-of-strokes-due-to-intracranial-atherosclerosis-one-year-data-from-hyderabad-stroke-registry
#7
Raghu Ram, Subhash Kaul, Suvarna Alladi, Jabeen S Afshan, T Surya Prabha, Abhijeet Kohat, Swetha Tandra, Jyotsna Y Rani
Background: Intracranial atherosclerotic stenosis (ICAS) is a common cause of ischemic stroke in Asian countries and probably in India. Aim: The aim of this study was to describe the risk factors, distribution of vascular lesions, recurrence and outcome of stroke due to ICAS. Methodology: A total of 100 consecutive patients of ischemic stroke due to ICAS were enrolled prospectively from January 1, 2015, to December 31, 2015, and followed for 1 year for treatment compliance and recurrence...
October 2017: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/29171361/canadian-stroke-best-practice-recommendations-secondary-prevention-of-stroke-sixth-edition-practice-guidelines-update-2017
#8
Theodore Wein, M Patrice Lindsay, Robert Côté, Norine Foley, Joseph Berlingieri, Sanjit Bhogal, Aline Bourgoin, Brian H Buck, Jafna Cox, Dion Davidson, Dar Dowlatshahi, Jim Douketis, John Falconer, Thalia Field, Laura Gioia, Gord Gubitz, Jeffrey Habert, Sharon Jaspers, Cheemun Lum, Dana McNamara Morse, Paul Pageau, Mubeen Rafay, Amanda Rodgerson, Bill Semchuk, Mukul Sharma, Ashkan Shoamanesh, Arturo Tamayo, Elisabeth Smitko, David J Gladstone
The 2017 update of The Canadian Stroke Best Practice Recommendations for the Secondary Prevention of Stroke is a collection of current evidence-based recommendations intended for use by clinicians across a wide range of settings. The goal is to provide guidance for the prevention of ischemic stroke recurrence through the identification and management of modifiable vascular risk factors. Recommendations include those related to diagnostic testing, diet and lifestyle, smoking, hypertension, hyperlipidemia, diabetes, antiplatelet and anticoagulant therapies, carotid artery disease, atrial fibrillation, and other cardiac conditions...
January 1, 2017: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/29167390/early-elevated-troponin-levels-after-ischemic-stroke-suggests-a-cardioembolic-source
#9
Shadi Yaghi, Andrew D Chang, Brittany A Ricci, Mahesh V Jayaraman, Ryan A McTaggart, Morgan Hemendinger, Priya Narwal, Katarina Dakay, Brian Mac Grory, Shawna M Cutting, Tina M Burton, Christopher Song, Emile Mehanna, Matthew Siket, Tracy E Madsen, Michael Reznik, Alexander E Merkler, Michael P Lerario, Hooman Kamel, Mitchell S V Elkind, Karen L Furie
BACKGROUND AND PURPOSE: Elevated cardiac troponin is a marker of cardiac disease and has been recently shown to be associated with embolic stroke risk. We hypothesize that early elevated troponin levels in the acute stroke setting are more prevalent in patients with embolic stroke subtypes (cardioembolic and embolic stroke of unknown source) as opposed to noncardioembolic subtypes (large-vessel disease, small-vessel disease, and other). METHODS: We abstracted data from our prospective ischemic stroke database and included all patients with ischemic stroke during an 18-month period...
January 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29137053/prognostic-value-of-high-resolution-magnetic-resonance-imaging-in-evaluating-carotid-atherosclerotic-plaque-in-patients-with-ischemic-stroke
#10
Jin-Er Shu, Ming-Liang Ying, Xiao-Rong Chen, Jian-Jun Hua, Jie-Ting Fu, Xiu-Mei Xia, Yong-Hao Pan, Yang Jiang
BACKGROUND: Ischemic stroke (IS) is a devastating occurrence affecting millions worldwide. This study aimed to evaluate the prognostic value of high-resolution magnetic resonance imaging (HRMRI) in assessing carotid atherosclerotic plaque in IS patients. METHODS: Between January 2013 and March 2015, 338 IS patients were recruited for the investigative purposes of the study. All participants of the study underwent an HRMRI inspection procedure after being admitted into the hospital...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29118311/factors-associated-with-intima-media-complex-thickness-of-the-common-carotid-artery-in-japanese-noncardioembolic-stroke-patients-with-hyperlipidemia-the-j-stars-echo-study
#11
Shinichi Wada, Masatoshi Koga, Kazunori Toyoda, Kazuo Minematsu, Masahiro Yasaka, Yoji Nagai, Shiro Aoki, Tomohisa Nezu, Naohisa Hosomi, Tatsuo Kagimura, Hideki Origasa, Kenji Kamiyama, Rieko Suzuki, Toshiho Ohtsuki, Hirofumi Maruyama, Kazuo Kitagawa, Shinichiro Uchiyama, Masayasu Matsumoto
AIMS: There may be ethnic differences in carotid atherosclerosis and its contributing factors between Asian and other populations. The purpose of this study was to examine intima-media complex thickness (IMT) of the carotid artery and associated clinical factors in Japanese stroke patients with hyperlipidemia from a cohort of the Japan Statin Treatment Against Recurrent Stroke Echo Study. METHODS: Patients with hyperlipidemia, not on statins, who developed noncardioembolic ischemic stroke were included in this study...
November 8, 2017: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/29094912/recurrent-ischemic-stroke-strategies-for-prevention
#12
REVIEW
Rupal Oza, Kristen Rundell, Miriam Garcellano
Recurrent strokes make up almost 25% of the nearly 800,000 strokes that occur annually in the United States. Risk factors for ischemic stroke include hypertension, diabetes mellitus, hyperlipidemia, sleep apnea, and obesity. Lifestyle modifications, including tobacco cessation, decreased alcohol use, and increased physical activity, are also important in the management of patients with a history of stroke or transient ischemic attack. Antiplatelet therapy is recommended to reduce the risk of recurrent ischemic stroke...
October 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/29069841/impact-of-hyperlipidemia-and-atrial-fibrillation-on-the-efficacy-of-endovascular-treatment-for-acute-ischemic-stroke-a-meta-analysis
#13
Jingwei Zheng, Ligen Shi, Weilin Xu, Ningning Zhao, Feng Liang, Jingyi Zhou, Jianmin Zhang
INTRODUCTION: Stroke is the crucial cause of death annually. Inconsistent results from the randomized controlled trials (RCTs) aroused controversy on efficacy of endovascular treatment (EVT). MATERIALS AND METHODS: To evaluate the efficacy of EVT in stroke patients. We searched three databases including PubMed, Web of science and the Cochrane Library from Jan 2011 to Apr 2017. Eligible studies were RCTs comparing EVT versus standard medical therapy alone. The primary outcomes were favorable functional outcomes (modified Rankin Scale score, 0-2) at 3 months...
September 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/29065954/the-relationship-between-obstructive-sleep-apnea-and-ruptured-intracranial-aneurysms
#14
Oleg Y Chernyshev, Shyamal C Bir, Tanmoy K Maiti, Devi Prasad Patra, Hai Sun, Bharat Guthikonda, Cesar Liendo, Hugo Cuellar, Alireza Minagar, Anil Nanda
STUDY OBJECTIVES: The role of obstructive sleep apnea (OSA) in the overall outcome of ruptured intracranial aneurysms (RIAs) is unknown. We have investigated the role of OSA in overall outcome of RIAs. METHODS: Data from 159 consecutive patients were retrospectively reviewed. A chi-square test and regression analysis were performed to determine the significant difference. A value of P< .05 was considered significant. RESULTS: The prevalence of OSA in RIAs was fivefold higher in the nonaneurysm patient group, P = ...
October 18, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29053913/morphological-changes-of-the-internal-carotid-artery-prevalence-and-characteristics-a-clinical-and-ultrasonographic-study-in-a-series-of-19-804-patients-over-25-years-old
#15
H F G Martins, A Mayer, P Batista, F Soares, V Almeida, A J Pedro, V Oliveira
BACKGROUND AND PURPOSE: Morphological changes of the internal carotid arteries (McICA) are frequently found during cervical ultrasound studies. However, the etiology of McICA remains controversial. During this study, the prevalence and demographic characteristics of McICA, such as kinking, coiling or looping identified by Doppler ultrasound, were analysed and its relationship with vascular risk factors and stroke was assessed. METHODS: A retrospective study was performed by analysing 19 804 patients who were subjected to cervical ultrasonographic study between January 2000 and June 2012...
October 20, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29053905/distinct-predictive-role-of-collateral-status-on-clinical-outcome-in-variant-stroke-subtypes-of-acute-large-arterial-occlusion
#16
Xuting Zhang, Meixia Zhang, Wenhong Ding, Shenqiang Yan, David S Liebeskind, Min Lou
BACKGROUND: Clinical trials have showed that robust collateral flow has a relationship with good clinical outcome, however, different stroke subtypes were lumped together. This study explored the relationship between baseline collaterals and the onset-to-imaging time (OIT), and the correlation between pre-treatment collateral status and clinical outcome among different subtypes. METHOD: We reviewed prospectively collected data from consecutive acute ischemic stroke (AIS) patients with acute middle cerebral artery occlusion who received reperfusion therapy...
October 20, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29021257/presence-characteristics-and-prognostic-associations-of-carotid-plaque-among-people-living-with-hiv
#17
Sumbal A Janjua, Pedro V Staziaki, Balint Szilveszter, Richard A P Takx, Thomas Mayrhofer, Orla Hennessy, Hamed A Emami, Jakob Park, Alexander Ivanov, Travis R Hallett, Michael T Lu, Javier M Romero, Steven K Grinspoon, Udo Hoffmann, Markella V Zanni, Tomas G Neilan
BACKGROUND: Data from broad populations have established associations between incidental carotid plaque and vascular events. Among people living with HIV (PLWHIV), the risk of vascular events is increased; however, whether incidental carotid plaque is increased and there is an association between incidental carotid plaque, plaque characteristics, and vascular events among PLWHIV is unclear. METHODS AND RESULTS: Data from the multi-institutional Research Patient Data Registry were used...
October 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28948451/a-diagnostic-approach-to-stroke-in-young-adults
#18
REVIEW
Christopher A Stack, John W Cole
Optimal diagnosis and management of stroke in young adults benefit from a multidisciplinary team, including a vascular neurology specialist. In addition to the "standard" vascular risk factors including smoking, hypertension, diabetes, and hyperlipidemia, one needs to consider alternative etiologies including substance abuse, carotid/vertebral artery dissections, and rare genetic conditions among others. Once a young patient is determined to have had a stroke, the next question a clinician should ask is why did this patient have a stroke? A "heart to head" diagnostic approach is recommended...
September 25, 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28920508/internal-carotid-artery-dissection-among-younger-and-older-patients-with-acute-ischemic-stroke
#19
Y Amsalem, L Porat, M C Javitt, E Sprecher, G Telman
BACKGROUND: Carotid artery dissection (CAD) is a known causative factor in the etiology of acute ischemic stroke in young patients. However, the significance of CAD in older patients with acute ischemic stroke is unclear with only a few prior clinical studies. In order to isolate the influence of CAD as an independent factor, we performed multivariate analysis of common covariables in acute ischemic stroke patients in northern Israel. PATIENTS AND METHODS: 347 consecutive patients who suffered from acute ischemic stroke had initial CT angiography (CTA) ordered from the emergency room...
September 16, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28904464/clinical-features-risk-factors-and-short-term-outcome-of-ischemic-stroke-in-patients-with-atrial-fibrillation-data-from-a-population-based-study
#20
William G Akanksha, Kaur Paramdeep, Singh Gagandeep, Bansal Rajinder, S Paul Birinder, Singla Monika, Singh Shavinder, J Samuel Clarence, J Verma Shweta, Meenakshi Sharma, D Pandian Jeyaraj
OBJECTIVES: Atrial fibrillation (AF) is the most common sustained cardiac rhythm disorder associated with stroke. This study was done to describe risk factors, clinical features, and short-term outcomes of stroke patients with AF. MATERIALS AND METHODS: This study was a part of the Indian Council of Medical Research funded "Ludhiana urban population based Stroke Registry." Data were collected using WHO STEPS stroke method. All patients ≥18 years of age, who developed ischemic stroke between March 26, 2011, and March 25, 2013, were included in this study...
July 2017: Annals of Indian Academy of Neurology
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