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cvt, cerebral venous thrombosis

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https://www.readbyqxmd.com/read/29441008/diagnosis-and-treatment-of-cerebral-venous-thrombosis-a-review
#1
REVIEW
Yaxi Luo, Xin Tian, Xuefeng Wang
Cerebral venous thrombosis (CVT), also called cerebral venous sinus thrombosis (CVST), is a cerebrovascular disease with diverse clinical manifestations that often affects young adults, women of childbearing age, and children. It's most common clinical manifestations are headache, seizures, altered consciousness, and neurological focal signs on physical examination. CVT can manifest as a single symptom, or it can present as a syndrome consisting of multiple symptoms. This non-specific clinical picture makes diagnosing CVT difficult...
2018: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29436443/diagnosis-and-management-of-cerebral-venous-thrombosis
#2
Roya Behrouzi, Martin Punter
Cerebral venous thrombosis (CVT) is rare and accounts for 0.5% of all strokes. Its clinical presentation is variable and diagnosis requires a high index of clinical suspicion in conjunction with neuroradiological diagnostic support. Treatment options are limited and are mostly based on consensus. Therefore, familiarity with international guidelines is important. Outcome is often good and most patients make a full recovery, although a small proportion suffers death or disability. Here, we describe the clinical features, risk factors, acute imaging features, management and complications of CVT...
February 2018: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/29402471/direct-oral-anticoagulant-use-in-patients-with-thrombophilia-antiphospholipid-syndrome-or-venous-thrombosis-of-unusual-sites-a-narrative-review
#3
REVIEW
Laurent Bertoletti, Ygal Benhamou, Yannick Béjot, Sylvestre Marechaux, Saida Cheggour, Boris Aleil, Nicolas Lellouche, Jean-Guillaume Dillinger, Aurélien Delluc
Direct oral anticoagulants (DOACs) are indicated in the treatment and prevention of venous thromboembolism (VTE). However, the use of DOACs in unusual VTE, including cerebral venous thrombosis (CVT) and splanchnic venous thrombosis (SVT), and in patients with biological thrombophilia including minor thrombophilia (Factor V Leiden and prothrombin G20210A), major innate thrombophilia (protein C and S deficiency, and antithrombin) and major acquired thrombophilia (antiphospholipid syndrome [APS]), remains controversial due to the paucity of available data...
February 2, 2018: Blood Reviews
https://www.readbyqxmd.com/read/29390539/oral-contraceptives-caused-venous-sinus-thrombosis-complicated-with-cerebral-artery-infarction-and-secondary-epileptic-seizures-a-case-report-and-literature-review
#4
Feng Xu, Cuifang Liu, Xiaobo Huang
RATIONALE: Venous sinus thrombosis is a special type of cerebrovascular disease. Its incidence is low and its symptoms are lack of specificity. And its early diagnosis and treatment are very difficult. PATIENT CONCERNS: This paper reported a rare case of a 43-year-old female who presented with cerebral venous thrombosis (CVT) complicated with cerebral artery infarction and secondary epileptic seizures due to oral contraceptives. DIAGNOSES: The final diagnosis was intracranial venous sinus thrombosis, acute cerebral infarction in the left parietal lobe, intracranial hypertension syndrome, and continuous epilepsy...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29362628/cerebral-venous-thrombosis-in-a-patient-with-iron-deficiency-anemia-and-thrombocytopenia-a-case-report
#5
Walaa A Kamel, Jasem Y Al-Hashel, K John Alexander, Fathi Massoud, Fatima Al Shawaf, Ibtisam E Al Huwaidi
AIM: To report a potential association of thrombosis, thrombocytopenia with iron deficiency anaemia. CASE REPORT: A 43-year-old female experienced an episode of a headache, with bilateral papilledema by neurological examination, magnetic resonance venography (MRV) brain showed cerebrovenous thrombosis (CVT), iron deficiency anaemia and thrombocytopenia by blood investigations, that was treated with iron supplementations and anticoagulation. CONCLUSION: In this patient, cerebrovenous thrombosis (CVT) was discovered in a patient with thrombocytopenia and iron deficiency anaemia and treated with iron supplements and anticoagulation, we concluded that thrombocytopenia is not a protective factor against thrombosis especially with iron deficiency anaemia...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29341411/the-effect-of-recanalization-on-long-term-neurological-outcome-after-cerebral-venous-thrombosis
#6
E Rezoagli, I Martinelli, D Poli, U Scoditti, S M Passamonti, P Bucciarelli, W Ageno, F Dentali
BACKGROUND: Studies with limited sample size and with discordant results described the recanalization time course of cerebral venous thrombosis (CVT). The neurological outcome after a first episode of CVT is good, but the role of recanalization on the neurological dependency is still debated. OBJECTIVES: The aim of the study is to assess the recanalization rate after cerebral venous thrombosis (CVT) and its prognostic role on long-term neurological outcome. PATIENTS/METHODS: In a retrospective observational multicentre cohort study, patients with an acute first episode of CVT with at least one available imaging test during follow-up were enrolled...
January 16, 2018: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29322704/evaluation-of-cerebral-venous-thrombosis-by-ct-mri-and-mr-venography
#7
Pratibha Issar, Sirasapalli Chinna, Sanjeev Kumar Issar
Objective: To study and compare cerebral parenchymal changes and sinuses involvement in CT with MRI and MRV in Cerebral Venous Thrombosis patients. Method: This study was carried out in the Department of Radiodiagnosis, JLN Hospital and Research Center, Bhilai, Chhattisgarh from October 2012 to Nov 2014 and includes fifty patients of all age groups presenting with clinical symptoms of CVT, admitted in Neurology, Neurosurgery, Medicine, Pediatric, obstetric and Gynecology wards...
November 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/29310406/cerebral-venous-thrombosis-originating-from-internal-jugular-vein-outflow-impairment-a-case-report
#8
Chunxiao Li, Li Sun, Xiuzhen Zhao, Mingqin Zhu, Ying Zhang
RATIONALE: Cerebral venous thrombosis (CVT) comprises a group of cerebral vascular diseases resulting from cerebral venous outflow obstruction caused by various etiologies. The etiology of CVT is complex, including infectious and noninfectious factors. The diagnosis is difficult. As a result, many patients are misdiagnosed or never diagnosed. This patient was diagnosed with CVT due to unilateral internal jugular vein compression. PATIENT CONCERNS: In this report, we present a case of acute onset CVT in a 15-year-old female patient who presented with a headache, nausea, and vomiting as the main clinical manifestations...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29284999/high-burden-of-stroke-risk-factors-in-developing-country-the-case-study-of-bosnia-herzegovina
#9
Marija Bender, Edin Jusufovic, Vesna Railic, Sima Kelava, Selma Tinjak, Damir Dzevdetbegovic, Dario Mot, Mensuda Tresnjo, Sandra Lakicevic, Natasa Pejanovic-Skobic, Osman Sinanovic
Introduction: The burden of stroke has been increasing worldwide, especially in developing countries. Very few data regarding epidemiology of stroke are available in Bosnia and Herzegovina (BH). Patients and methods: We undertook a retrospective hospital-based study in all hospitals existing in five cantons and one district of BH. The patients were recruited between January 1st, 2014, and December 31st, 2014, and only first-ever-in-lifetime strokes (FES) were included for evaluation...
December 2017: Materia Socio-medica
https://www.readbyqxmd.com/read/29277281/yield-of-computed-tomography-ct-angiography-in-patients-with-acute-headache-normal-neurological-examination-and-normal-non-contrast-ct-a-meta-analysis
#10
Imanda M E Alons, Ben F J Goudsmit, Korne Jellema, Marianne A A van Walderveen, Marieke J H Wermer, Ale Algra
BACKGROUND: Patients with acute severe headache, normal neurological examination, and a normal noncontrast head computed tomography (NCCT) may still have subarachnoid hemorrhage, cerebral venous thrombosis (CVT), cervical arterial dissection, or reversible cerebral vasoconstriction syndrome (RCVS). Computed tomography angiography (CTA) is used increasingly in the emergency department for evaluating this, but its added value remains controversial. METHODS: We retrospectively collected data on the diagnostic yield of CTA in patients with acute severe headache, normal neurological examination, and normal NCCT who received additional CTA in the acute phase in 2 secondary referral centers for vascular neurology...
December 22, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29250028/the-structural-imaging-characteristics-and-its-clinical-relevance-in-patients-with-cerebral-venous-thrombosis-a-retrospective-analysis-from-one-single-center-in-china
#11
Li-Xin Zhou, Ming Yao, Li-Ying Cui, Ming-Li Li, Yi-Cheng Zhu, Jun Ni, Bin Peng
Background: Few studies have investigated structural imaging findings of cerebral venous thrombosis (CVT) in China. The structural imaging [head computed tomography (CT) and routine brain magnetic resonance imaging (MRI)] can assess any parenchymal lesion secondary to the venous thrombosis and reveal direct signs of intraluminal thrombus. In recent years, many patients can be diagnosed with CVT more rapidly and directly by structural imaging. The aim of the present study is to determine the performance of structural imaging in the diagnosis and outcome of CVT in a large cohort single center of Chinese patients...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29246198/cortical-vein-thrombosis-in-adult-patients-of-cerebral-venous-sinus-thrombosis-correlates-with-poor-outcome-and-brain-lesions-a-retrospective-study
#12
Jiahui Liang, Hongbing Chen, Zhuhao Li, Shaofu He, Boning Luo, Shujin Tang, Wenjin Shang, Jinsheng Zeng
BACKGROUND: Cortical vein thrombosis (CVT) receives little attention in adult patients with cerebral venous sinus thrombosis (CVST). This study aimed to investigate the clinical and radiological features of adult CVST patients with concomitant CVT. METHODS: From May 2009 to May 2016, we recruited 44 adult CVST patients (diagnosed within 1 month of onset; 33.8 ± 14.0 years of age, 28 males). CVT was primarily confirmed using computed tomography venography and magnetic resonance imaging sequence of contrast enhanced three dimensions magnetization prepared rapid acquisition with gradient echo...
December 15, 2017: BMC Neurology
https://www.readbyqxmd.com/read/29230173/blueberry-phenolics-reduce-gastrointestinal-infection-of-patients-with-cerebral-venous-thrombosis-by-improving-depressant-induced-autoimmune-disorder-via-mir-155-mediated-brain-derived-neurotrophic-factor
#13
Ning Xu, Hao Meng, Tianyi Liu, Yingli Feng, Yuan Qi, Donghuan Zhang, Honglei Wang
Cerebral venous thrombosis (CVT) often causes human depression, whereas depression-induced low immunity makes the patients susceptible to gastrointestinal infection. Blueberry possesses antidepressant properties which may improve autoimmunity and reduce gastrointestinal infection. Brain-derived neurotrophic factor (BDNF) performs antidepressant function and can be regulated by miR-155, which may be affected by blueberry. To explore the possible molecular mechanism, blueberry compounds were analyzed by high-performance liquid chromatography...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29211360/cerebral-venous-thrombosis-as-a-diagnostic-challenge-clinical-and-radiological-correlation-based-on-the-retrospective-analysis-of-own-cases
#14
Anna Zimny, Edyta Dziadkowiak, Joanna Bladowska, Justyna Chojdak-Łukasiewicz, Aleksandra Loster-Niewińska, Marek Sąsiadek, Bogusław Paradowski
BACKGROUND: Cerebral venous thrombosis (CVT) is a rare condition which constitutes 0.5-1% of all strokes. The clinical and radiological picture of CVT is non-specific and can mimic other disorders. OBJECTIVES: The aim of the study was to retrospectively evaluate and correlate clinical and radiological symptoms presented by patients with CVT, both in the initial and follow-up neurological and neuroimaging examinations, with a special emphasis on diagnostic difficulties...
October 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29203685/cerebral-venous-thrombosis-in-older-patients
#15
Susanna M Zuurbier, Sini Hiltunen, Erik Lindgren, Suzanne M Silvis, Katarina Jood, Sharon Devasagayam, Timothy J Kleinig, Frank L Silver, Daniel M Mandell, Jukka Putaala, Turgut Tatlisumak, Jonathan M Coutinho
BACKGROUND AND PURPOSE: Cerebral venous thrombosis (CVT) is rare in older patients. We investigated whether clinical features and outcomes differ in older and younger patients. METHODS: We used data from a multicenter observational registry of consecutive adult patients with CVT admitted between 1987 and 2016. We compared demographics, clinical manifestations, and outcomes between older (upper quartile of the age distribution) and younger (lower 3 quartiles of the age distribution) patients...
January 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29202678/approach-to-thrombosis-at-unusual-sites-splanchnic-and-cerebral-vein-thrombosis
#16
REVIEW
Nicoletta Riva, Walter Ageno
Splanchnic vein thrombosis (SVT) and cerebral vein thrombosis (CVT) are two manifestations of unusual site venous thromboembolism (VTE). SVT includes thrombosis in the portal, mesenteric or splenic veins, and the Budd-Chiari syndrome. CVT encompasses thrombosis of the dural venous sinuses and thrombosis of the cerebral veins. Unusual site VTE often represents a diagnostic and therapeutic challenge because of the heterogeneity in clinical presentation, the limited evidence available in the literature on the acute and long-term prognosis of these diseases, and the lack of large randomized controlled trials evaluating different treatment options...
December 2017: Vascular Medicine
https://www.readbyqxmd.com/read/29159843/vocational-outcome-in-cerebral-venous-thrombosis-long-term-follow-up-study
#17
E Lindgren, K Jood, T Tatlisumak
OBJECTIVES: Few studies have investigated long-term functional outcome in patients with cerebral venous thrombosis (CVT). We aimed to evaluate return to work (RTW) after CVT and its association with self-reported life satisfaction, quality of life, health, participation, fatigue, depression, and anxiety. METHODS: From hospital records, we identified all patients diagnosed with CVT in Sahlgrenska University Hospital between 1996 and 2016 and invited all survivors to a clinical follow-up visit >1 year after onset...
November 21, 2017: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29146874/imaging-characteristics-of-venous-parenchymal-abnormalities
#18
Audrey Arnoux, Aude Triquenot-Bagan, Daniela Andriuta, David Wallon, Evelyne Guegan-Massardier, Claire Leclercq, Olivier Martinaud, Mélody Castier-Amouyel, Olivier Godefroy, Jean-Marc Bugnicourt
BACKGROUND AND PURPOSE: There are few published data on the patterns of parenchymal imaging abnormalities in a context of cerebral venous thrombosis (CVT). The objectives of the present study were to describe the patterns of parenchymal lesions associated with CVT and to determine the lesion sites. METHODS: We included 44 consecutively hospitalized patients with CVT and parenchymal lesions on magnetic resonance imaging. The diagnosis of CVT had been confirmed by magnetic resonance imaging/magnetic resonance venography...
December 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29128928/serum-neuron-specific-enolase-may-be-a-marker-to-predict-the-severity-and-outcome-of-cerebral-venous-thrombosis
#19
Yanyu Hu, Ran Meng, Xuxiang Zhang, Linlin Guo, Sijie Li, Yan Wu, Jiangang Duan, Yuchuan Ding, Xunming Ji
The objective is to explore the effective of baseline serum neuron specific enolase (NSE) on predicting the severity and outcome in patients with cerebral venous thrombosis (CVT). A total of 156 patients confirmed as CVT in Xuanwu Hospital were enrolled in this retrospective study from March 2011 through September 2016. The severity was evaluated with the National Institutes of Health Stroke Score (NIHSS), intracranial pressure (ICP), and CVT-related complications; the outcome was evaluated by modified Rankin Scale (mRS); the relationship between baseline serum NSE and mRS was analyzed with receiver operating characteristic curve (ROC), logistic regression analysis, and Kaplan-Meier curves...
November 11, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/29125690/cancer-and-risk-of-cerebral-venous-thrombosis-a-case-control-study
#20
S M Silvis, S Hiltunen, E Lindgren, K Jood, S M Zuurbier, S Middeldorp, J Putaala, S C Cannegieter, T Tatlisumak, J M Coutinho
BACKGROUND: Cancer is an established risk factor for leg vein thrombosis and pulmonary embolism. Controlled studies assessing the risk of cerebral venous thrombosis (CVT) in patients with cancer have not been performed. OBJECTIVE: To assess whether cancer is a risk factor for CVT. PATIENTS/METHODS: Case-control study. We assessed consecutive adult patients with CVT from three academic hospitals from 1987-2015, and control subjects from the Dutch MEGA study (Multiple Environmental and Genetic Assessment of risk factors for venous thrombosis)...
November 10, 2017: Journal of Thrombosis and Haemostasis: JTH
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