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https://www.readbyqxmd.com/read/28079831/gastric-cancer-burden-of-last-40-years-in-north-china-hebei-province-a-population-based-study
#1
Di Liang, Suoyuan Liang, Jing Jin, Daojuan Li, Jin Shi, Yutong He
Gastric cancer (GC) is the second leading cause of cancer death in China. It is well known that Cixian in Hebei Province is one of the highest risk areas of GC in China and worldwide. This study aims to accurate assessment of GC burden and trend in high-risk area (Hebei Province) from 1973 to 2013. The authors analyzed GC data from 21 population-based cancer registries which represented 15.25% of the entire population of Hebei Province. The collected data were stratified by 5-year age groups, gender, and area...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28079232/predictive-features-for-histology-of-gastric-subepithelial-lesions
#2
Ricardo Teles Schulz, Lizandra Castilho Fabio, Matheus Cavalcante Franco, Sheila A Siqueira, Paulo Sakai, Fauze Maluf-Filho
BACKGROUND: - Gastric subepithelial lesion is a relatively common diagnosis after routine upper endoscopy. The diagnostic workup of an undetermined gastric subepithelial lesion should take into consideration clinical and endoscopic features. OBJECTIVE: - We aimed to investigate the association between patients' characteristics, endoscopic and echographic features with the histologic diagnosis of the gastric subepithelial lesions. METHODS: - This is a retrospective study with 55 patients, who were consecutively diagnosed with gastric subepithelial lesions, from October 2008 to August 2011...
January 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28076476/do-proximal-and-distal-gastric-tumours-behave-differently
#3
Laurence Bedin da Costa, Marcelo Garcia Toneto, Luis Fernando Moreira
Background: Although the incidence of gastric (adenocarcinoma) cancer has been decreasing over time, it is still one of the most common malignancies worldwide, and proximal tumours tend to have a worse prognosis. Aim: To compare surgical outcomes and prognosis between proximal - excluding tumours of the cardia - and distal gastric cancer. Methods: Out of 293 cases reviewed - 209 with distal and 69 with proximal gastric cancer - were compared for clinical and pathological features, stage, surgical outcome, mortality and survival...
November 2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/28067081/-relationship-of-consequences-of-anastomotic-insufficiency-and-bacterial-flora-of-oral-cavity-in-patients-with-esophageal-and-cardia-cancer
#4
Ákos Balázs, Beáta Winkler, Katalin Kristóf, László Harsányi, Lívia Bokor
INTRODUCTION: In the course of anastomotic insufficiency following resection of esophageal cancers the bacterial compound of the esophageal substance has a remarkable, presumable role in the outcome of complications. AIM: The purpose of this study is to compare the consequences of the anastomotic leak with the bacterial flora of patients' oral cavity. METHOD: In this prospective study a total of 131 patients were investigated directly before the surgical intervention taking a bacterial sample...
January 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28057966/abdominal-manifestations-of-extranodal-lymphoma-pictorial-essay
#5
Laís Fajardo, Guilherme de Araujo Ramin, Thiago José Penachim, Daniel Lahan Martins, Patrícia Prando Cardia, Adilson Prando
In the appropriate clinical setting, certain aspects of extranodal abdominal lymphoma, as revealed by current cross-sectional imaging techniques, should be considered potentially diagnostic and can hasten the diagnosis. In addition, diagnostic imaging in the context of biopsy-proven lymphoma can accurately stage the disease for its appropriate treatment. The purpose of this article was to illustrate the various imaging aspects of extranodal lymphoma in the abdomen.
November 2016: Radiologia Brasileira
https://www.readbyqxmd.com/read/28053294/investigation-of-factors-affecting-clinical-outcomes-after-stent-placement-in-malignant-obstruction-of-the-esophagus-or-the-gastric-cardia
#6
EDITORIAL
Ji Bong Jeong, Dong-Won Ahn
No abstract text is available yet for this article.
January 15, 2017: Gut and Liver
https://www.readbyqxmd.com/read/28053055/cancer-incidence-and-mortality-risks-in-a-large-us-barrett-s-oesophagus-cohort
#7
Michael B Cook, Sally B Coburn, Jameson R Lam, Philip R Taylor, Jennifer L Schneider, Douglas A Corley
OBJECTIVE: Barrett's oesophagus (BE) increases the risk of oesophageal adenocarcinoma by 10-55 times that of the general population, but no community-based cancer-specific incidence and cause-specific mortality risk estimates exist for large cohorts in the USA. DESIGN: Within Kaiser Permanente Northern California (KPNC), we identified patients with BE diagnosed during 1995-2012. KPNC cancer registry and mortality files were used to estimate standardised incidence ratios (SIR), standardised mortality ratios (SMR) and excess absolute risks...
January 4, 2017: Gut
https://www.readbyqxmd.com/read/28041610/-paediatric-pharmacobezoar-in-vitamin-overdose
#8
Nataliz Vega-Mata, Laura Fernández-García, Carolina Lara-Cardenas, Lucía Raposo-Rodríguez, María Montes-Granda
BACKGROUND: Pharmacobezoars are aggregates of undigested medications that accumulate in the gastrointestinal tract and can cause obstructive or toxic complications. In this paper, the first case is reported of a paediatric pharmacobezoar formation after a vitamin overdose. The objective of this report is to prevent the occurrence of this complication and the action to be taken. CLINIC CASE: A 6-year-old child, 6h after ingesting 40 chewable tablets of a hydrophobic vitamin E with high capacity to form a pharmacobezoar, underwent urgent oesophagogastroscopy...
December 29, 2016: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/28040054/histological-and-histochemical-characterization-of-the-digestive-tract-of-european-catfish-silurus-glanis-linnaeus-1758
#9
S Köprücü, M Yaman
In this study was to examined the morphology, histology and histochemically the digestive tract of European catfish, Silurus glanis. Two-four age S. glanis obtained from Çelik Lake (Gölbaşı-Adıyaman, Turkey). Six S. glanis, 59-71 cm length, 1.5-3.2 kg weight used for in the investigation. The body cavity was opened and samples of digestive tract (esophagus, stomach and intestine) were fixed in neutral buffered 10% formalin and embedded in paraffin. Dewaxed section (5-6 µm) were deparaffinized and stained with haematoxylin and eosin (H&E), Crossman triple, periodic acid-shiff (PAS), alcian blue (AB, pH 1...
November 30, 2016: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28036293/a-retrospective-study-of-nens-and-mir-224-promotes-apoptosis-of-bon-1-cells-by-targeting-pcsk9-inhibition
#10
Jian'an Bai, He Na, Xiumei Hua, Yaling Wei, Tian Ye, Yiqiang Zhang, Guo Jian, Weiwen Zeng, Lijun Yan, Qiyun Tang
Neuroendocrine neoplasms (NENs) represent relatively rare tumors. The lack of diagnostic, therapeutic method and prognostic factors makes them a challenge to us. We retrospectively reviewed the data of 205 NENs patients among which 157 cases were followed-up. Proprotein convertase subtilisin/kexin 9 (PCSK9), a regulator of low density lipoprotein cholesterol (LDL-C), was confirmed as a target gene of microRNA-224. We found an increased incidence of NENs from 2012 to 2015. Women were usually diagnosed at earlier stages than men (P < 0...
December 28, 2016: Oncotarget
https://www.readbyqxmd.com/read/28031722/low-plce1-levels-are-correlated-with-poor-prognosis-in-hepatocellular-carcinoma
#11
Ya Cheng, Song-Ge Xing, Wei-Dong Jia, Mei Huang, Na-Na Bian
BACKGROUND: Previous reports show that phospholipase C epsilon-1 (PLCE1) expression is positively correlated with esophageal squamous cell carcinoma and gastric cardia adenocarcinomas; however, the expression of PLCE1 in hepatocellular carcinoma (HCC) and its correlation with clinical outcome still remain unclear. The aim of this study was to explore the expression of PLCE1 in HCC tissue and to determine whether PLCE1 was a prognostic factor for HCC patients. MATERIALS AND METHODS: PLCE1 levels in 20 paired HCC tissues and corresponding paracarcinomatous tissues was investigated by quantitative real-time polymerase chain reaction and Western blot assays...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/28028499/barrett-s-mucosa-segmentation-in-endoscopic-images-using-a-hybrid-method-spatial-fuzzy-c-mean-and-level-set
#12
Hossein Yousefi-Banaem, Hossein Rabbani, Peyman Adibi
Barrett's mucosa is one of the most important diseases in upper gastrointestinal system that caused by gastro-esophagus reflux. If left untreated, the disease will cause distal esophagus and gastric cardia adenocarcinoma. The malignancy risk is very high in short segment Barrett's mucosa. Therefore, lesion area segmentation can improve specialist decision for treatment. In this paper, we proposed a combined fuzzy method with active models for Barrett's mucosa segmentation. In this study, we applied three methods for special area segmentation and determination...
October 2016: Journal of Medical Signals and Sensors
https://www.readbyqxmd.com/read/28018426/combination-of-five-body-positions-can-effectively-improve-the-rate-of-gastric-mucosa-s-complete-visualization-by-applying-magnetic-guided-capsule-endoscopy
#13
Yuting Qian, Sheng Wu, Qi Wang, Lumin Wei, Wei Wu, Lifu Wang, Ye Chu
Objectives. Achieving a comprehensive view of gastric mucosa has been a challenge for magnetic-guided capsule endoscopy (MGCE) for years. This study works on optimizing the performance of MGCE by changing the conventional positions to the five body positions. Methods. Sixty patients were enrolled in the study and underwent MGCE. All patients were asked to adopt five body positions (left lateral, supine, right lateral, knee-chest, and sitting). In each position, the ability to visualize the six gastric landmarks (cardia, fundus, body, angulus, antrum, and pylorus) was assessed...
2016: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28018111/clinical-features-of-upper-gastrointestinal-serrated-lesions-an-endoscopy-database-analysis-of-98746-patients
#14
Hai-Long Cao, Wen-Xiao Dong, Meng-Que Xu, Yu-Jie Zhang, Si-Nan Wang, Mei-Yu Piao, Xiao-Cang Cao, Bang-Mao Wang
AIM: To analyse the clinical features of patients with the serrated lesions in the upper gastrointestinal tract (UPGI) tract. METHODS: Patients who underwent routine esophagogastroduodenoscopy (EGD) at the Digestive Endoscopy Centre of General Hospital, Tianjin Medical University between January 2011 and December 2015 were consecutively recruited. Patients with UPGI serrated lesions were consecutively identified. The patients' demographics and histopathology were recorded...
December 7, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28002320/ca125-is-a-potential-biomarker-to-predict-surgically-incurable-gastric-and-cardia-cancer-a-retrospective-study
#15
Taobo Luo, Wenhu Chen, Lifang Wang, Hongguang Zhao
Preoperative evaluation of the curability of gastric and cardia cancer is important to avoid risks of unnecessary surgery. Our previous study has reported several clinical parameters associated with incurable gastric surgery. In this study, we aimed to evaluate the correlation between CA125 and the curability of gastric and cardia cancer.A total of 297 cases of gastric and cardia cancer were analyzed retrospectively, including 153 cases with radical surgery and 144 with surgery for incurable gastric or cardia cancer...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27999828/a-case-of-abdominal-mesenteric-castleman-s-disease-with-left-renal-cell-carcinoma-and-stomach-leiomyoma
#16
Shunjun Chen, Lele Song, Xinli Xie, Xingmin Han, Bing Cheng
: A rare case of abdominal mesenteric Castleman's disease with left renal cell carcinoma and stomach leiomyoma is reported. A 57 years old male patient was transferred to our hospital for investigation of a left kidney tumor. Physical examination and routine laboratory tests were normal. Multi mode imaging by 64-slices spiral computed tomography (CT) scan, the enhanced CT scan and the fluorine-18-fluorodeoxyglucose positron emission tomography/CT ((18)F-FDG PET/CT) scan were applied. Computed tomography showed a 5...
September 2016: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/27999692/polypoid-dysplasia-in-barrett-s-esophagus-diagnosis-management-and-very-different-outcomes-in-two-consecutive-cases
#17
Megan Murphy, Christina Tofani, Kunjal Gandhi, Anthony Infantolino
Background. Barrett's esophagus is associated with an increased risk of adenocarcinoma. Dysplasia in Barrett's esophagus is a precursor to adenocarcinoma. Rarely, dysplastic polypoid lesions are superimposed on Barrett's esophagus. Most reported cases of polypoid dysplasia in Barrett's esophagus have been advanced on presentation and treated with esophagectomy. We describe two cases of polypoid changes in Barrett's esophagus and treatment with polypectomy followed by radiofrequency ablation. Cases. A 75 yo male presented with esophageal polyps, which on biopsy showed gastric cardia/foveolar mucosa with focal intestinal metaplasia without dysplasia...
2016: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/27987905/physico-chemical-characterization-of-succinyl-chitosan-stabilized-liposomes-for-the-oral-co-delivery-of-quercetin-and-resveratrol
#18
Carla Caddeo, Ramon Pons, Claudia Carbone, Xavier Fernàndez-Busquets, Maria Cristina Cardia, Anna Maria Maccioni, Anna Maria Fadda, Maria Manconi
In the present work, quercetin and resveratrol, natural polyphenols with strong antioxidant and anti-inflammatory properties, were co-loaded in polymer-associated liposomes conceived for oral delivery, by exploiting the potential of pH-sensitive succinyl-chitosan. Chitosan was succinylated, characterized by Nuclear Magnetic Resonance spectroscopy and Gel Permeation Chromatography, and used to form a protective shell on the surface of liposomes. The physico-chemical properties of the succinyl-chitosan liposomes were assessed by light scattering, zeta potential, cryogenic transmission electron microscopy, and small angle X-ray scattering...
February 10, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/27986126/aberrant-cpg-island-shore-region-methylation-of-cav1-is-associated-with-tumor-progression-and-poor-prognosis-in-gastric-cardia-adenocarcinoma
#19
Yan-Li Guo, Tie-Nian Zhu, Wei Guo, Zhi-Ming Dong, Zhen Zhou, Yu-Jie Cui, Rui-Jing Zhao
BACKGROUND AND AIMS: Caveolin-1 (CAV1) is a multifunctional scaffolding protein and plays an important role in tumorigenesis. However, the epigenetic changes of CAV1 in gastric cardia adenocarcinoma (GCA) have not been investigated so far. The purpose of this study was to clarify the contribution of critical CpG sites in CAV1 to progression/prognosis of GCA and to further elucidate the effect of critical CpG sites on the ectopic expression of β-catenin in GCA. METHODS: Methylation-specific polymerase chain reaction (MSP) and bisulfite genomic sequencing (BGS) methods were, respectively, applied to examine the methylation status of CAV1...
August 2016: Archives of Medical Research
https://www.readbyqxmd.com/read/27977508/open-versus-hand-assisted-laparoscopic-total-gastric-resection-with-d2-lymph-node-dissection-for-adenocarcinoma-a-case-control-study
#20
Guang-Tan Zhang, Xue-Dong Zhang, Huan-Zhou Xue
OBJECTIVE: A case-control study was conducted to investigate the feasibility and safety of hand-assisted laparoscopic total gastrectomy (HALTG) with D2 lymphadenectomy for gastric cancer as opposed to traditional open total gastrectomy (OTG). METHODS: One hundred fifty-four patients suffering cardia, upper, middle, or whole gastric cancer operated in our department from February 2009 to February 2012 were divided into 2 groups: the open total gastrectomy group (the OTG group) and the hand-assisted laparoscopic total gastrectomy group (the HALTG group)...
December 13, 2016: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
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