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https://www.readbyqxmd.com/read/28549104/near-infrared-image-guided-lymphatic-mapping-in-minimally-invasive-oesophagectomy-of-distal-oesophageal-cancer
#1
Olli Helminen, Johanna Mrena, Eero Sihvo
OBJECTIVES: We aimed to assess the potential of near-infrared (NIR) imaging during minimally invasive oesophagectomy in patients with distal oesophageal cancer for detection of nodal metastases inside and outside the standard en bloc surgical field. METHODS: We enrolled 6 patients diagnosed with distal oesophageal cancer for intraoperative lymphatic mapping with NIR imaging. Indocyanine green dye was injected endoscopically in 8 corners of the primary tumour at the start of the operation...
May 26, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28533838/-predictive-factors-of-medication-adherence-in-patients-with-chronic-heart-failure-morocco-s-experience
#2
Yassine Ragbaoui, Imad Nouamou, Ayoub El Hammiri, Rachida Habbal
Medication adherence in patients with chronic heart failure is recognized as one of the major issues in the management of this pathology. Demographic status and socioeconomic conditions in African countries may have an impact on chronic heart failure treatment adherence. We conducted a cross-sectional study of patients with heart failure treated in the center of heart failure in the Department of Cardiology at the IBN ROCHD University Hospital (Morocco) from September 2014 to January 2015. The extent of medication adherence was based on a questionary: CARDIA-Questionary...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28523307/mir-149-rs2292832-c-t-polymorphism-and-risk-of-gastric-cancer
#3
Raluca Alexandra Cîmpeanu, Dragoş Marian Popescu, Florin Burada, Mihai Gabriel Cucu, Dan IonuŢ Gheonea, Mihai Ioana, Ion Rogoveanu
Accumulating evidence that microRNA (miRNA) genes are involved in different processes associated with gastric carcinogenesis. The polymorphisms located on miRNA sequences may affect the interaction with their target messenger RNAs (mRNAs) and, consequently, genetic susceptibility to disease. The aim of our study was to investigate the association of miR-149 rs2292832 C>T polymorphism and gastric cancer susceptibility in Romanian patients. A total of 142 patients with gastric adenocarcinoma and 288 healthy controls were included in this study...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28521815/proportion-of-cancer-in-a-middle-eastern-country-attributable-to-established-risk-factors
#4
Maya A Charafeddine, Sara H Olson, Deborah Mukherji, Sally N Temraz, Ghassan K Abou-Alfa, Ali I Shamseddine
BACKGROUND: Providing an estimate of the percentage of cancer in Lebanon by 2018 that is due to the exposure to risk factors in 2008. Factors include: smoking, body mass index (BMI), physical inactivity, dietary factors, alcohol consumption, infections, and air pollution in adults. METHOD: Population Attributable Fraction (PAF) was calculated using the proportion of the population exposed and relative risks for each risk factor from meta-analyses. The PAF estimates the proportion of cases in which exposure may have played a causal role...
May 18, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28521427/immunoexpression-of-lactoferrin-in-triple-negative-breast-cancer-patients-a-proposal-to-select-a-less-aggressive-subgroup
#5
Antonio Ieni, Valeria Barresi, Luana Licata, Roberta Cardia, Carmine Fazzari, Giuseppe Nuciforo, Francesco Caruso, Michele Caruso, Vincenzo Adamo, Giovanni Tuccari
Triple-negative breast cancer (TNBC) indicates a subset of breast carcinomas that does not express estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor-2 (HER2). According to the literature, TNBCs are aggressive tumors, characterized by a high incidence of recurrence and a high risk of disease progression. Lactoferrin (LF) is a single-chain, iron-binding glycoprotein of ~700 amino acids, which is involved in a wide range of biological activities, including iron-trafficking and carcinogenesis...
May 2017: Oncology Letters
https://www.readbyqxmd.com/read/28511859/reference-ranges-and-regional-patterns-of-left-ventricular-strain-and-strain-rate-using-two-dimensional-speckle-tracking-echocardiography-in-a-healthy-middle-aged-black-and-white-population-the-cardia-study
#6
Henrique T Moreira, Chike C Nwabuo, Anderson C Armstrong, Satoru Kishi, Ola Gjesdal, Jared P Reis, Pamela J Schreiner, Kiang Liu, Cora E Lewis, Stephen Sidney, Samuel S Gidding, João A C Lima, Bharath Ambale-Venkatesh
BACKGROUND: Strain and strain rate are sensitive markers of left ventricular (LV) myocardial function. The aim of this study was to assess reference ranges and regional patterns of LV strain and strain rate using two-dimensional speckle-tracking echocardiography in a large population of black and white subjects. METHODS: This study involved a retrospective review of prospectively collected images in 557 participants in the Coronary Artery Risk Development in Young Adults study who remained healthy at the year 25 examination...
May 13, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28505341/association-of-changes-in-neighborhood-level-racial-residential-segregation-with-changes-in-blood-pressure-among-black-adults-the-cardia-study
#7
Kiarri N Kershaw, Whitney R Robinson, Penny Gordon-Larsen, Margaret T Hicken, David C Goff, Mercedes R Carnethon, Catarina I Kiefe, Stephen Sidney, Ana V Diez Roux
Importance: Despite cross-sectional evidence linking racial residential segregation to hypertension prevalence among non-Hispanic blacks, it remains unclear how changes in exposure to neighborhood segregation may be associated with changes in blood pressure. Objective: To examine the association of changes in neighborhood-level racial residential segregation with changes in systolic and diastolic blood pressure over a 25-year period. Design, Setting, and Participants: This observational study examined longitudinal data of 2280 black participants of the Coronary Artery Risk Development in Young Adults (CARDIA) study, a prospective investigation of adults aged 18 to 30 years who underwent baseline examinations in field centers in 4 US locations from March 25, 1985, to June 7, 1986, and then were re-examined for the next 25 years...
May 15, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28484733/per-oral-endoscopic-myotomy-for-achalasia-cardia-outcomes-in-over-400-consecutive-patients
#8
Zaheer Nabi, Mohan Ramchandani, Radhika Chavan, Rakesh Kalapala, Santosh Darisetty, Guduru Venkat Rao, Nageshwar Reddy
Background and study aims Per-oral endoscopic myotomy (POEM) has emerged as an efficacious treatment modality for the management of achalasia cardia (AC) and non-achalasia spastic esophageal motility disorders. Initial results are encouraging. We analyzed the safety and efficacy of POEM in a large cohort of patients with AC. Patients and methods The data from patients who underwent POEM (from January 2013 to June 2016) was prospectively collected and analyzed. Clinical success was defined as Eckardt score ≤ 3 after POEM procedure...
May 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28480729/an-unusual-cause-of-boerhaave%C3%A2-s-syndrome-in-a-young-patient
#9
Samuel Fernandes, Carlos Noronha Ferreira, José Freire, José Velosa
An 18-year-old male patient with a history of atopy and intermittent dysphagia for solids, presented to the emergency department with sudden onset total dysphagia followed by hematemesis, after ingesting an ibuprofen tablet. Urgent upper gastrointestinal endoscopy revealed a deep laceration just above the tablet impacted in the distal esophagus. Abdominal CT-scan confirmed the suspicion of an esophageal perforation. The impacted tablet was broken up with biopsy forceps, and a covered metallic stent (Hanarostent® 60/100x20/26mm) was placed across the cardia effectively excluding the fistula...
May 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28469215/postoperative-eyelid-metastasis-of-a-gastric-cardia-adenocarcinoma
#10
Gao-Shi Huang, Yun Jin
No abstract text is available yet for this article.
May 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28467284/clinical-topographical-anatomy-of-the-gastro-oesophageal-junction-in-the-cat
#11
Agni Voutsinou, Lysimachos G Papazoglou, Ioannis Antonopoulos, Timoleon S Rallis
Objectives The purpose of the present study was to describe histologically the gastro-oesophageal junction in the cat and interrelationships of this region. Our hypothesis was that cats are devoid of abdominal oesophagus. Methods Three centimetres of the terminal oesophagus, the phreno-oesophageal membrane with 1-2 cm margins of the diaphragmatic crural muscle and the proximal 3 cm of the gastric cardia were obtained from nine domestic shorthair cats and one domestic longhair cat that were euthanased for reasons other than digestive tract pathology...
May 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28461064/evaluation-of-transabdominal-ultrasound-with-oral-cellulose-based-contrast-agent-in-the-detection-and-surveillance-of-gastric-ulcer
#12
Zhijun Liu, Jintao Guo, Shupeng Wang, Ying Zhao, Zhining Liu, Jing Li, Weidong Ren, Shaoshan Tang, Limei Xie, Ying Huang, Siyu Sun, Liping Huang
The aim of this study was to assess the role of transabdominal ultrasound with cellulose-based oral contrast agent (TUS-OCCA) in the detection and surveillance of gastric ulcer. The study was approved by the institutional review board at Shengjing Hospital of China Medical University. A total of 124 consecutive patients with benign gastric ulcer diagnosed by gastroscopy and biopsy were enrolled. Serial TUS-OCCA (approximately 1 exam every 2 wk) was performed to monitor the effects of treatment, and additional interventions were planned according to the results...
April 28, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28458240/vibrational-and-optical-characterization-of-s-triazine-derivatives
#13
Luigi Stagi, Daniele Chiriu, Marek Scholz, Carlo Maria Carbonaro, Riccardo Corpino, Andrea Porcheddu, Suvi Rajamaki, Giancarlo Cappellini, Roberto Cardia, Pier Carlo Ricci
The optical and electron properties of three different s-triazine derivatives are investigated to ascertain the role of the donor acceptor character in amine-triazine systems depending on the bridging radical of the ammine group. The three derivatives were obtained starting from three different ammine compounds allowing to achieve a structure with a triazine core, surrounded by three ammine group and terminated with cyano or methyl or oxy-methyl functional group. Experimental optical data were interpreted in view of the electronic insights gathered by means of density functional theory simulations on base compounds...
April 20, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28453616/prevalence-and-predictors-of-diastolic-dysfunction-according-to-different-classification-criteria-the-coronary-artery-risk-development-in-young-in-adults-study
#14
Laura J Rasmussen-Torvik, Laura A Colangelo, Joao A C Lima, David R Jacobs, Carlos J Rodriguez, Samuel S Gidding, Donald M Lloyd-Jones, Sanjiv J Shah
Heart failure with preserved ejection fraction is often preceded by diastolic dysfunction (DD). Of several published DD criteria, it is unclear which, if any, are applicable to data obtained in epidemiologic cohorts. We evaluated the prevalence of DD using previously published definitions in a population-based study, the Coronary Artery Risk Development in Young Adults (CARDIA) Study, using data gathered in 2010-2011. Echocardiography was performed on 3,474 individuals (mean age = 50.2 years) at the CARDIA year 25 examination...
April 27, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28453609/invited-commentary-searching-for-the-perfect-measure-of-diastolic-dysfunction-a-futile-exercise
#15
Ambarish Pandey, Jarett D Berry
Heart failure with preserved ejection fraction (HFpEF) is common, recalcitrant to treatment, and associated with poor outcomes. Diastolic dysfunction (DD) is an independent predictor of HFpEF risk, associated clinical manifestations, and long-term outcomes. However, the usefulness of diastolic function assessment is limited by the heterogeneity in the existing definitions of DD. In this issue of the Journal, Rasmussen-Torvik et al. (Am J Epidemiol. 2017;000(00):000-000) have highlighted this problem by evaluating the prevalence and concordance of 4 established definitions of DD in the Coronary Artery Risk Development in Young Adults (CARDIA) cohort...
April 27, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28443204/association-of-genotypes-of-rs671-withinaldh2-with-risk-for-gastric-cardia-adenocarcinoma-in-the-chinese-han-population-in-high-and-low-incidence-areas
#16
Lian-Qun Zhang, Xin Song, Xue-Ke Zhao, Jia Huang, Peng Zhang, Lu-Wen Wang, Hui Meng, Jian-Wei Ku, Guo-Qiang Kong, Tao Jiang, Xin-Min Li, Xiao-Long Lv, Teng Ma, Guo Yuan, Min-Jie Wu, Shou-Jia Hu, Shuang Lv, Tang-Juan Zhang, Ling-Fen Ji, Zong-Min Fan, Neng-Chao Wang, Yao-Wen Zhang, Fu-You Zhou, Li-Dong Wang
OBJECTIVE: : This study aimed to determine if gastric cardia adenocarcinoma (GCA) risk was associated with the lys (A or *2) allele at the rs671 (glu504lys) polymorphism within the aldehyde dehydrogenase 2 (ALDH2) gene in a Chinese Han population. We also aimed to investigateALDH2 genotypic distributions between subjects from high- and low-incidence areas for both GCA and esophageal squamous cell carcinoma (ESCC). METHODS: : We designed a case-control study including 2,686 patients with GCA and 3,675 control subjects from high- and low-incidence areas for both GCA and ESCC in China...
February 2017: Cancer Biology & Medicine
https://www.readbyqxmd.com/read/28441708/dosimetric-comparison-of-three-different-radiotherapy-techniques-in-antrum-located-stomach-cancer
#17
Alparslan Serarslan, Nilgun Ozbek Okumus, Bilge Gursel, Deniz Meydan, Yalcin Dastan, Talat Aksu
Background: The current optimal radiotherapy (RT) planning technique for stomach cancer is controversial. The design of RT for stomach cancer is difficult and differs according to tumor localization. Dosimetric and clinical studies have been performed in patients with different tumor localizations. This may be the main source of inconsistencies in study results. For this reason, we attempted to find the optimal RT technique for patients with stomach cancer in similar locations. Methods: This study was based on the computed tomography datasets of 20 patients with antrum-located stomach cancer...
March 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28441380/comparison-of-general-obesity-and-measures-of-body-fat-distribution-in-older-adults-in-relation-to-cancer-risk-meta-analysis-of-individual-participant-data-of-seven-prospective-cohorts-in-europe
#18
Heinz Freisling, Melina Arnold, Isabelle Soerjomataram, Mark George O'Doherty, José Manuel Ordóñez-Mena, Christina Bamia, Ellen Kampman, Michael Leitzmann, Isabelle Romieu, Frank Kee, Konstantinos Tsilidis, Anne Tjønneland, Antonia Trichopoulou, Paolo Boffetta, Vassiliki Benetou, H B As Bueno-de-Mesquita, José María Huerta, Hermann Brenner, Tom Wilsgaard, Mazda Jenab
BACKGROUND: We evaluated the associations of anthropometric indicators of general obesity (body mass index, BMI), an established risk factor of various cancer, and body fat distribution (waist circumference, WC; hip circumference, HC; and waist-to-hip ratio, WHR), which may better reflect metabolic complications of obesity, with total obesity-related and site-specific (colorectal and postmenopausal breast) cancer incidence. METHODS: This is a meta-analysis of seven prospective cohort studies participating in the CHANCES consortium including 18 668 men and 24 751 women with a mean age of 62 and 63 years, respectively...
May 23, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28440945/heterogeneity-in-esophageal-and-gastric-cardia-precursor-progression-during-six-year-endoscopic-surveillance-after-population-based-screening-in-a-chinese-high-risk-region
#19
Denggui Wen, Liwei Zhang, Xiaoling Wang, Xiaoduo Wen, Yi Yang, Yuetong Chen, Guiying Wang, Kohei Akazawa, Shijie Wang, Baoen Shan
BACKGROUND: The study was conducted to examine esophageal and gastric cardia precursor progression. METHODS: After population-based baseline screening, 145 precursor and 335 chronic inflammation cases were endoscopically surveyed for six years. RESULTS: Surveillance of interval and baseline diagnoses for 18 severe dysplasia (SD) cases later detected were: 13, 23, 39, and 44 months since a diagnosis of chronic inflammation in four cases; 6, 6, 6, 11, 13, 16, 16, and 23 months since mild dysplasia (mD) diagnoses in eight; and 6, 9, 10, 13, 18, and 48 months since moderate dysplasia (MD) diagnoses in six...
April 25, 2017: Thoracic Cancer
https://www.readbyqxmd.com/read/28430644/red-and-processed-meat-consumption-and-gastric-cancer-risk-a-systematic-review-and-meta-analysis
#20
REVIEW
Zhanwei Zhao, Zifang Yin, Qingchuan Zhao
The associations between red and processed meat consumption and gastric cancer risk have remained inconclusive. We performed a systematic review and meta-analysis to analyze these associations. We searched PubMed and EMBASE to identify studies published from inception through October 2016. Subtype analyses of gastric cancer (gastric cardia adenocarcinoma and gastric non-cardiac adenocarcinoma) and dose-response analyses were performed. We finally selected 42 eligible studies. The summary relative risks of highest versus lowest consumption were positive for case-control studies with 1...
May 2, 2017: Oncotarget
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