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https://www.readbyqxmd.com/read/28645108/prognostic-factors-influencing-the-survival-of-patients-with-carcinoma-of-the-gastric-cardia-receiving-preoperative-interventional-embolization-chemotherapy
#1
Hai-Li Cao, Shu-Qiang Jin, Kai-Bing Wang, Bin Bai
The purpose of this study was to analyze the characteristics of patients with gastric cardia cancer (GCC) to identify the main factors the influence the survival rate after interventional embolization chemotherapy (IEC). One hundred and fifty-six patients with advanced GCC were treated with IEC via the left gastric artery. Survival time was defined as from the date of diagnosis until death or the end of this study in June 2015. The median survival time was 15 months (range 3 to 29 months). The Cox proportional hazard model found that patients' age (p< 0...
June 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/28642615/the-bethe-slater-curve-revisited-new-insights-from-electronic-structure-theory
#2
R Cardias, A Szilva, A Bergman, I Di Marco, M I Katsnelson, A I Lichtenstein, L Nordström, A B Klautau, O Eriksson, Y O Kvashnin
The Bethe-Slater (BS) curve describes the relation between the exchange coupling and interatomic distance. Based on a simple argument of orbital overlaps, it successfully predicts the transition from antiferromagnetism to ferromagnetism, when traversing the 3d series. In a previous article [Phys. Rev. Lett. 116, 217202 (2016)] we reported that the dominant nearestneighbour (NN) interaction for 3d metals in the bcc structure indeed follows the BS curve, but the trends through the series showed a richer underlying physics than was initially assumed...
June 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28628619/south-african-ebola-diagnostic-response-in-sierra-leone-a-modular-high-biosafety-field-laboratory
#3
Janusz T Paweska, Petrus Jansen van Vuren, Gunther H Meier, Chantel le Roux, Ousman S Conteh, Alan Kemp, Cardia Fourie, Prabha Naidoo, Serisha Naicker, Phumza Ohaebosim, Nadia Storm, Orienka Hellferscee, Lisa K Ming Sun, Busisiwe Mogodi, Nishi Prabdial-Sing, Desiree du Plessis, Deidre Greyling, Shayne Loubser, Mark Goosen, Stewart D McCulloch, Terence P Scott, Alexandra Moerdyk, Wesley Dlamini, Kelfala Konneh, Idrissa L Kamara, Dauda Sowa, Samuel Sorie, Brima Kargbo, Shabir A Madhi
BACKGROUND: In August 2014, the National Institute for Communicable Diseases (NICD) in South Africa established a modular high-biosafety field Ebola diagnostic laboratory (SA FEDL) near Freetown, Sierra Leone in response to the rapidly increasing number of Ebola virus disease (EVD) cases. METHODS AND FINDINGS: The SA FEDL operated in the Western Area of Sierra Leone, which remained a "hotspot" of the EVD epidemic for months. The FEDL was the only diagnostic capacity available to respond to the overwhelming demand for rapid EVD laboratory diagnosis for several weeks in the initial stages of the EVD crisis in the capital of Sierra Leone...
June 19, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28621190/-watermelon-stomach-can-be-the-cause-of-severe-gastrointestinal-bleeding
#4
István Sugár, Zoltán Ráth, Pál Ondrejka, Zsolt Iványi, Bálint Scheich, Judit Várkonyi
Irregular vascular dilatation in the antrum or the cardia of the stomach can be the cause of severe gastrointestinal bleeding. The first term for it - in the beginning of the 50's of the previous century - was GAVE (Gastric Antral Vascular Ectasia) since at that time no similar phenomenon had been registered before. A quarter of a century later, after publishing a few cases, a witty internist described it as "watermelon stomach" because the macroscopic picture is similarly looking as the aforesaid fruit's appearing...
June 2017: Magyar Sebészet
https://www.readbyqxmd.com/read/28611977/clinicopathology-of-early-gastric-carcinoma-an-update-for-pathologists-and-gastroenterologists
#5
REVIEW
Qin Huang, Xiaoping Zou
BACKGROUND: The WHO defines early gastric carcinoma (EGC) as invasive carcinoma up to the submucosal layer, regardless of nodal metastasis. The recent study results indicate that EGC varies in location, histology, nodal metastasis, and prognosis. SUMMARY: The heterogeneity in EGC may be related to various types of epithelial stem cells. The most important stem cells include Lgr5(+) cells at the base of a gastric unit in the antrum-pylorus-cardia, Mist1(+) cells at the isthmus/Troy(+) cells at the base in the corpus-fundus, and Sox2(+) cells at the base in almost all regions...
March 2017: Gastrointestinal Tumors
https://www.readbyqxmd.com/read/28610678/anti-m%C3%A3-llerian-hormone-follicle-stimulating-hormone-antral-follicle-count-and-risk-of-menopause-within-5-years
#6
Catherine Kim, James C Slaughter, Erica T Wang, Duke Appiah, Pamela Schreiner, Benjamin Leader, Ronit Calderon-Margalit, Barbara Sternfeld, David Siscovick, Melissa Wellons
OBJECTIVE: To evaluate the ability of concentration of anti-Müllerian hormone (AMH), antral follicle count (AFC), and concentration of follicle stimulating hormone (FSH) to predict the onset of menopause. STUDY DESIGN: The Coronary Artery Risk Development in Young Adults Study (CARDIA) Women's Study was an ancillary study to CARDIA, a population-based study of adults aged 18-30 years followed for 3 decades. For this report, participants were women (n=426) who had attended the CARDIA year 15-16 (2000-2001) examination, had at least one ovary, were not pregnant, and underwent serum AMH and FSH measurement and transvaginal ultrasonography in 2002-2003...
August 2017: Maturitas
https://www.readbyqxmd.com/read/28606594/biodanza-reduces-acute-pain-severity-in-women-with-fibromyalgia
#7
Víctor Segura-Jiménez, Claudia M Gatto-Cardia, Clélia M Martins-Pereira, Manuel Delgado-Fernández, Virginia A Aparicio, Ana Carbonell-Baeza
Biodanza is a useful therapy for the fibromyalgia management; however, there is no evidence of its effectiveness on acute pain. The objectives of the present study were: to determine the changes of a 3-month Biodanza program on acute pain severity (before vs. after session) and cumulative pain severity in women with fibromyalgia; and to check the associations of acute pain severity reduction with presession pain severity, body fat percentage, and satisfaction with the session. This was a 3-month low-moderate intensity (rate of perceived exertion around 12, based on a 6-20 point scale) Biodanza intervention study (1 session/week)...
June 9, 2017: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
https://www.readbyqxmd.com/read/28605327/impact-of-high-altitude-on-clinicopathological-features-and-prognosis-after-r0-resection-for-gastric-cancer-a-population-based-multicenter-study
#8
MULTICENTER STUDY
Jiuda Zhao, Feng Du, Yu Zhang, Haihong Zhu, Li Dong, Guoshuang Shen, Fangchao Zheng, Hui Chen, Junhui Zhao, Faxiang Ji, Yang Luo, Fei Ma, Ziyi Wang, Binghe Xu
Geographic variation has an important role in both carcinogenesis and prognosis of gastric cancer (GC). High altitude is a special hypoxic environment that is also correlated with the occurrence of GC. Different onset features and prognoses of GC in high altitude with respect to plains are rarely reported and remain unknown. This multicenter study compared different clinicopathological characteristics and prognoses of patients with resected GC who were from locations of both high altitudes and plains in China...
2017: Journal of Environmental Pathology, Toxicology and Oncology
https://www.readbyqxmd.com/read/28600361/coding-of-barrett-s-oesophagus-with-high-grade-dysplasia-in-national-administrative-databases-a-population-based-cohort-study
#9
Georgina Chadwick, Mira Varagunam, Christian Brand, Stuart A Riley, Nick Maynard, Tom Crosby, Julie Michalowski, David A Cromwell
OBJECTIVES: The International Classification of Diseases 10th Revision (ICD-10) system used in the English hospital administrative database (Hospital Episode Statistics (HES)) does not contain a specific code for oesophageal high-grade dysplasia (HGD). The aim of this paper was to examine how patients with HGD were coded in HES and whether it was done consistently. SETTING: National population-based cohort study of patients with newly diagnosed with HGD in England...
June 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28598812/cyclind1-and-p57-kip2-as-biomarkers-in-differentiation-metastasis-and-prognosis-of-gastric-cardia-adenocarcinoma
#10
Yi Ru, Xiao-Jie Chen, Zhi-Wei Zhao, Peng-Fei Zhang, Shuai-Hao Feng, Qiang Gao, She-Gan Gao, Xiao-Shan Feng
OBJECTIVE: This study aims to investigate the expression and significance of p57(kip2) and cyclinD1 in gastric cardia adenocarcinoma (GCA). p57(kip2) is a negative regulator in the cell cycle. On the contrary, cyclinD1 is a positive regulator of cell cycle progression. METHODS: Thirty-two cases of GCA tissues and adjacent non-cancerous tissues were collected for this study. Immunohistochemistry and fluorescence qualitative PCR was used to determine the level of p57(kip2) and cyclinD1 in GCA and its adjacent non-cancerous tissues...
May 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/28597288/safety-and-efficacy-of-endoscopic-submucosal-dissection-of-large-%C3%A2-3%C3%A2-cm-subepithelial-tumors-located-in-the-cardia
#11
Jun Li, Jian Tang, G W Lua, Jie Chen, Xingang Shi, Feng Liu, Zhaoshen Li
BACKGROUND: Upper gastrointestinal subepithelial tumors (SETs) may harbor potential malignancy. Although it is well recognized that large SETs should be resected, the treatment strategy remains controversial. Compared to surgical resection, endoscopic resection has many advantages such as less invasive, shorter hospital stay, lower costs, and better quality of life. However, Endoscopic resection of large SETs in the cardia is challenging. The purpose of this study was to evaluate the safety and efficacy of endoscopic submucosal dissection (ESD) in the treatment of such SETs...
June 8, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28596958/circulating-cellular-adhesion-molecules-and-cognitive-function-the-coronary-artery-risk-development-in-young-adults-study
#12
Cynthia Yursun Yoon, Lyn M Steffen, Myron D Gross, Lenore J Launer, Andrew Odegaard, Alexander Reiner, Otto Sanchez, Kristine Yaffe, Stephen Sidney, David R Jacobs
OBJECTIVE: Higher circulating concentrations of cellular adhesion molecules (CAMs) can be used as markers of endothelial dysfunction. Given that the brain is highly vascularized, we assessed whether endothelial function is associated with cognitive performance. METHOD: Within the Coronary Artery Risk Development in Young Adults (CARDIA) Study, excluding N = 54 with stroke before year 25, we studied CAMs among N = 2,690 black and white men and women in CARDIA year 7 (1992-1993, ages 25-37) and N = 2,848 in CARDIA year 15 (2000-2001, ages 33-45)...
2017: Frontiers in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28594442/body-mass-index-and-risk-of-gastric-cancer-a-30-year-follow-up-study-in-the-linxian-general-population-trial-cohort
#13
Jin-Hu Fan, Jian-Bing Wang, Shao-Ming Wang, Christian C Abnet, You-Lin Qiao, Philip R Taylor
Although a number of previous studies have noted either positive or no association for body mass index (BMI) and gastric cancers risk, little evidence exists in the Chinese population. We prospectively examined the associations of BMI with risk of gastric cancers in the Linxian General Population Trial cohort, with 29,584 healthy adults enrolled in 1985 and followed through the end of 2014. Body weight and height were measured during physical examination at baseline and BMI was calculated as weight in kilograms divided by height in meters squared...
June 8, 2017: Cancer Science
https://www.readbyqxmd.com/read/28593551/esophageal-motility-disorders-symptomatic-and-manometric-spectrum-in-punjab-northern-india
#14
Omesh Goyal, Monika Bansal, Ajit Sood
BACKGROUND: Data on the spectrum of esophageal motility disorders in Indian population are scarce. We aimed to study the symptomatic and manometric profile of patients with suspected esophageal motility disorders. METHODS: Consecutive patients with esophageal symptoms who underwent esophageal high-resolution manometry (HRM) from January 2010 to December 2014 were included in this retrospective analysis of prospectively acquired data. HRM was performed with 22-channel water-perfusion system and patients classified using Chicago classification v3...
June 8, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28590771/non-contrast-mr-angiography-using-three-dimensional-balanced-steady-state-free-precession-imaging-for-evaluation-of-stenosis-in-the-celiac-trunk-and-superior-mesenteric-artery-a-preliminary-comparative-study-with-computed-tomography-angiography
#15
Patricia Prando Cardia, Thiago José Penachim, Adilson Prando, Ulysses S Torres, Giuseppe D'Ippólito
OBJECTIVES: Although non-contrast magnetic resonance angiography (NC-MRA) is well established for the evaluation of renal artery stenosis, its usefulness in the evaluation of other abdominal aortic branches remains to be studied. This study aimed at evaluating the image quality and diagnostic accuracy of NC-MRA using a three-dimensional balanced steady-state free precession sequence (bSSFP) in identifying stenosis in the celiac trunk and superior mesenteric artery as compared to computed tomography angiography (CTA) as the reference standard...
June 7, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28586464/does-unmeasured-confounding-influence-associations-between-the-retail-food-environment-and-body-mass-index-over-time-the-coronary-artery-risk-development-in-young-adults-cardia-study
#16
Pasquale E Rummo, David K Guilkey, Shu Wen Ng, Katie A Meyer, Barry M Popkin, Jared P Reis, James M Shikany, Penny Gordon-Larsen
Background: Findings in the observational retail food environment and obesity literature are inconsistent, potentially due to a lack of adjustment for residual confounding. Methods: Using data from the CARDIA study ( n  = 12 174 person-observations; 6 examinations; 1985-2011) across four US cities (Birmingham, AL; Chicago, IL; Minneapolis, MN; Oakland, CA), we used instrumental-variables (IV) regression to obtain causal estimates of the longitudinal associations between the percentage of neighbourhood food stores or restaurants (per total food outlets within 1 km network distance of respondent residence) with body mass index (BMI), adjusting for individual-level socio-demographics, health behaviours, city, year, total food outlets and market-level prices...
June 6, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28575250/characterization-of-tissue-chromogranin-a-cga-immunostaining-and-clinicohistopathological-changes-for-the-125-chinese-patients-with-primary-small-cell-carcinoma-of-the-esophagus
#17
J W Ku, D Y Zhang, X Song, X M Li, X K Zhao, S Lv, S J Hu, R Cheng, F Y Zhou, H F Wu, L D Wang
The rarity of primary small cell carcinoma of the esophagus (PSCE) has limited the clinical feature and survival analysis with large sample size. Tissue chromogranin A (CgA) protein expression has been reported to be a useful biomarker for diagnosing PSCE. Interestingly, recent studies have indicated tissue CgA as a significant prognostic marker in multiple human cancers, but without PSCE. The present study, thus, was undertaken to characterize the clinicopathological changes and to evaluate the associations of tissue CgA expression with clinical response on Chinese PSCE patients...
August 1, 2017: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/28574971/per-oral-endoscopic-myotomy-in-children-first-experience-with-a-new-triangular-knife
#18
Zaheer Nabi, Mohan Ramchandani, Radhika Chavan, Manu Tandan, Rakesh Kalapala, Santosh Darisetty, D Nageshwar Reddy
OBJECTIVES: Per-oral endoscopic myotomy (POEM) is a novel treatment modality for achalasia cardia (AC). The procedure is technically challenging and time consuming. Recently, a new triangle knife (TTJ) has been introduced which is equipped with water jet facility. In this study, we analysed the feasibility, safety and efficacy of POEM in children with new triangle tip knife. METHODS: We retrospectively evaluated the data of children (≤18 years) who underwent POEM using TTJ knife at our institution...
June 2, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28568053/low-vitamin-b12-increases-risk-of-gastric-cancer-a-prospective-study-of-one-carbon-metabolism-nutrients-and-risk-of-upper-gastrointestinal-tract-cancer
#19
Eugenia H Miranti, Rachael Stolzenberg-Solomon, Stephanie J Weinstein, Jacob Selhub, Satu Männistö, Philip R Taylor, Neal D Freedman, Demetrius Albanes, Christian C Abnet, Gwen Murphy
Previous studies have found associations between one-carbon metabolism nutrients and risk of several cancers, but little is known regarding upper gastrointestinal tract (UGI) cancer. We analyzed prediagnostic serum concentrations of several one-carbon metabolism nutrients (vitamin B12, folate, vitamin B6, riboflavin and homocysteine) in a nested case-control study within the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study of male smokers, which was undertaken in Finland between 1985 and 1988...
May 31, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28561882/muc1-rs4072037-polymorphism-is-associated-with-decreased-risk-of-gastric-cancer-a-meta-analysis
#20
Yu Ye, Chong Yang, Lei Xu, Dilong Fang
BACKGROUND: Several studies have recently investigated the association between mucin 1 (MUC1) rs4072037 polymorphism and gastric cancer (GC) risk, but with conflicting results. The aim of this meta-analysis was to evaluate the association between MUC1 rs4072037 polymorphism and GC risk. METHODS: A comprehensive database search of PubMed, Elsevier, Embase and China National Knowledge Infrastructure (CNKI) databases was performed to identify relevant studies. Pooled odds ratios (ORs) and 95% confidence intervals (CIs) were used to assess the strength of any association...
May 26, 2017: International Journal of Biological Markers
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