An Staes, Katie Boucher, Sara Dufour, Teresa Mendes Maia, Evy Timmerman, Delphi Van Haver, Jarne Pauwels, Hans Demol, Jonathan Vandenbussche, Kris Gevaert, Francis Impens, Simon Devos
With current trends in proteomics, especially regarding clinical and low input (to single cell) samples, it is increasingly important to both maximize the throughput of the analysis and maintain as much sensitivity as possible. The new generation of mass spectrometers (MS) are taking a huge leap in sensitivity, allowing analysis of samples with shorter liquid chromatography (LC) methods while digging as deep in the proteome. However, the throughput can be doubled by implementing a dual column nano-LC-MS configuration...
April 22, 2024: Analytical Chemistry