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Enteral nutrition for acute pancreatitis

https://read.qxmd.com/read/37450700/the-2023-manctra-acute-biliary-pancreatitis-care-bundle-a-joint-effort-between-human-knowledge-and-artificial-intelligence-chatgpt-to-optimize-the-care-of-patients-with-acute-biliary-pancreatitis-in-western-countries
#21
JOURNAL ARTICLE
Mauro Podda, Marcello Di Martino, Benedetto Ielpo, Fausto Catena, Federico Coccolini, Francesco Pata, Giovanni Marchegiani, Belinda De Simone, Dimitrios Damaskos, Damian Mole, Ari Leppaniemi, Massimo Sartelli, Baohong Yang, Luca Ansaloni, Walter Biffl, Yoram Kluger, Ernest E Moore, Gianluca Pellino, Salomone Di Saverio, Adolfo Pisanu
OBJECTIVE: To generate an up-to-date bundle to manage acute biliary pancreatitis using an evidence-based, artificial intelligence (AI)-assisted GRADE method. SUMMARY BACKGROUND DATA: A care bundle is a set of core elements of care that are distilled from the most solid evidence-based practice guidelines and recommendations. METHODS: The research questions were addressed in this bundle following the PICO criteria. The working group summarized the effects of interventions with the strength of recommendation and quality of evidence applying the GRADE methodology...
July 17, 2023: Annals of Surgery
https://read.qxmd.com/read/37438694/catheter-directed-thrombolysis-versus-systemic-anticoagulation-in-the-treatment-of-symptomatic-splanchnic-venous-thrombosis-secondary-to-acute-pancreatitis-a-retrospective-cohort-study
#22
JOURNAL ARTICLE
Zongwen Zhang, Lin Gao, Zirui Liu, Gang Li, Bo Ye, Jing Zhou, Lu Ke, Zhihui Tong, Weiqin Li
BACKGROUND: Catheter-directed thrombolysis (CDT) has been an important therapy and seems effective in patients with splanchnic venous thrombosis (SVT) secondary to some diseases, but this intervention hasn't been formally evaluated in the setting of acute pancreatitis (AP). METHODS: This was a retrospective study enrolled patients between January 2013 and December 2018. AP patients who developed SVT-induced symptoms, including intractable ascites and/or enteral nutrition intolerance, were included...
July 12, 2023: BMC Surgery
https://read.qxmd.com/read/37404118/acute-pancreatitis-review
#23
JOURNAL ARTICLE
Yuting Huang, Dilhana S Badurdeen
Acute pancreatitis, a prevalent illness with devastating consequences, poses a grave threat to those affected. There has been a steady increase in the occurrence of acute pancreatitis at about 3% per year from 1961 to 2016. There are 3 main guidelines on acute pancreatitis, including the American College of Gastroenterology, the International Association of Pancreatology/American Pancreatic Association guideline in 2013, and the American Gastroenterological Association guideline in 2018. However, several milestone studies have been published since then...
August 2023: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://read.qxmd.com/read/37214572/controversies-in-the-management-of-acute-pancreatitis-an-update
#24
REVIEW
Manish Manrai, Saurabh Dawra, Anupam K Singh, Daya Krishna Jha, Rakesh Kochhar
This review summarized the current controversies in the management of acute pancreatitis (AP). The controversies in management range from issues involving fluid resuscitation, nutrition, the role of antibiotics and antifungals, which analgesic to use, role of anticoagulation and intervention for complications in AP. The interventions vary from percutaneous drainage, endoscopy or surgery. Active research and emerging data are helping to formulate better guidelines. The available evidence favors crystalloids, although the choice and type of fluid resuscitation is an area of dynamic research...
April 26, 2023: World Journal of Clinical Cases
https://read.qxmd.com/read/37206070/nutrition-in-acute-pancreatitis
#25
REVIEW
Srikanth Gopi, Anoop Saraya, Deepak Gunjan
Acute pancreatitis (AP) has varying severity, and moderately severe and severe AP has prolonged hospitalization and requires multiple interventions. These patients are at risk of malnutrition. There is no proven pharmacotherapy for AP, however, apart from fluid resuscitation, analgesics, and organ support, nutrition plays an important role in the management of AP. Oral or enteral nutrition (EN) is the preferred route of nutrition in AP, however, in a subset of patients, parenteral nutrition is required. EN has various physiological benefits and decreases the risk of infection, intervention, and mortality...
April 27, 2023: World Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/37111158/nutrition-in-acute-pancreatitis-from-the-old-paradigm-to-the-new-evidence
#26
REVIEW
Sara Sofia De Lucia, Marcello Candelli, Giorgia Polito, Rossella Maresca, Teresa Mezza, Tommaso Schepis, Antonio Pellegrino, Lorenzo Zileri Dal Verme, Alberto Nicoletti, Francesco Franceschi, Antonio Gasbarrini, Enrico Celestino Nista
The nutritional management of acute pancreatitis (AP) patients has widely changed over time. The "pancreatic rest" was the cornerstone of the old paradigm, and nutritional support was not even included in AP management. Traditional management of AP was based on intestinal rest, with or without complete parenteral feeding. Recently, evidence-based data underlined the superiority of early oral or enteral feeding with significantly decreased multiple-organ failure, systemic infections, surgery need, and mortality rate...
April 18, 2023: Nutrients
https://read.qxmd.com/read/37035927/impact-of-solid-food-provision-within-24%C3%A2-hours-of-hospital-admission-on-clinical-outcomes-for-adult-patients-with-acute-pancreatitis-a-literature-review
#27
REVIEW
Crystal Meyers, Diane Rigassio Radler, Rena S Zelig
Acute pancreatitis (AP) is a common gastrointestinal disease necessitating hospitalization, with incidence increasing both in the United States and worldwide. Some recent guidelines for hospitalized patients with AP recommend initiation of oral feeding within 24 h of admission; however, a lack of clarity regarding feeding time and diet orders in clinical practice still exists. This review presents recent randomized clinical trials regarding feeding administration for patients with mild to moderate AP...
April 10, 2023: Nutrition in Clinical Practice
https://read.qxmd.com/read/37033570/malnutrition-imparts-worse-outcomes-in-patients-admitted-for-acute-pancreatitis
#28
JOURNAL ARTICLE
Alexander Le, Amjad Shaikh, Mohsin Ali, Ayham Khrais, Yazan Abboud
Purpose Cessation of enteral nutrition is usually a part of the early stage of acute pancreatitis (AP) treatment. To our knowledge, there is no large database study that examines the effects of preexisting malnutrition on the morbidities of patients admitted for acute pancreatitis. We aimed to investigate the effects of malnutrition on patients admitted for acute pancreatitis. Methods Data between 2008 and 2014 from the National Inpatient Sample (NIS) database was extracted. Inclusion criteria included patients with a primary diagnosis of AP using the International Classification of Diseases, Ninth Revision (ICD-9) codes, and ages greater than 17...
March 2023: Curēus
https://read.qxmd.com/read/37021072/efficacy-of-enteral-nutrition-for-patients-with-acute-pancreatitis-a-systematic-review-and-meta%C3%A2-analysis-of-17-studies
#29
JOURNAL ARTICLE
Yafei Liu, Zhanou Wan, Dalin Liao
Nutrition support is a key method to treat acute pancreatitis (AP). Enteral nutrition (EN) has a role in treating AP, but the time point for EN initiation remains unclear. The present systematic review and meta-analysis aimed to assess the efficacy of early EN (EEN) and delayed EN (DEN) based on different time points (24, 48 and 72 h). The relevant databases including Pubmed, Web of Science, Embase and Cochrane library were searched until Dec 1, 2022. Studies comparing EEN and DEN in AP were included. The relative risk (RR) was used for comparing categorical variables, while standard mean difference (SMD) was used for continuous variables, both reported with 95% CI...
April 2023: Experimental and Therapeutic Medicine
https://read.qxmd.com/read/36958784/neostigmine-for-the-treatment-of-acute-pancreatitis-a-protocol-for-a-systematic-review-and-meta-analysis
#30
JOURNAL ARTICLE
Kun He, Xiaxiao Yan, Zihan Yang, Yuelun Zhang, Huijun Shu, Dong Wu
INTRODUCTION: Acute pancreatitis (AP) is a common disease with substantial mortality. Gut dysfunction may result in abdominal compartment syndrome (ACS) and delay enteral nutrition, worsening AP condition. Neostigmine is used as a prokinetic drug for the treatment of AP. But there are no recommendations from guidelines due to the lack of evidence. Therefore, we plan to conduct a systematic review and meta-analysis to explore the efficacy and safety of neostigmine for AP, aiming to provide current evidence for clinical practice...
March 23, 2023: BMJ Open
https://read.qxmd.com/read/36747275/efficacy-and-safety-of-neostigmine-on-treating-gastrointestinal-dysmotility-in-severe-acute-pancreatitis-patients-study-protocol-for-a-randomized-controlled-trial
#31
JOURNAL ARTICLE
Han Sun, Yaqi Sheng, Tiekuan Du, Huadong Zhu
BACKGROUND: Acute pancreatitis is a serious threat to human health and gastrointestinal dysmotility is a common complication for acute pancreatitis patients, resulting in delayed feeding, oral feeding intolerance, paralytic ileus, and abdominal compartment syndrome. Currently, there are limited treatment for this complication. Neostigmine is known to increase gastrointestinal motility and has been used to treat gastrointestinal dysmotility after surgery. However, research in treating acute pancreatitis with neostigmine is currently limited...
February 6, 2023: Trials
https://read.qxmd.com/read/36587014/quality-improvement-initiative-to-improve-timing-of-enteral-feeds-in-pediatric-acute-pancreatitis
#32
JOURNAL ARTICLE
Kate Templeton, Jenny Chan Yuen, Caitlin Lenz, Alison R Mann, Haley S Friedler, Ramy Yim, Maria Alfieri, Amy J Starmer, Amit S Grover
BACKGROUND: Acute pancreatitis (AP) represents a significant disease burden in the pediatric population. The management of AP includes fluid resuscitation, pain management, and early enteral feeds. Contrary to old dogma, early enteral feeding has been shown to improve outcomes and reduce hospital length of stay (LOS), yet uptake of this approach has not been standardized. Our aim was to standardize the management of AP, increasing the percentage of patients receiving early enteral nutrition from 40% to 65% within 12 months...
January 1, 2023: Pediatrics
https://read.qxmd.com/read/36562889/infections-in-acute-pancreatitis-organisms-resistance-patterns-and-effect-on-mortality
#33
JOURNAL ARTICLE
Fang Li, Feng Zhang, Xueqin Wan, Kesong Wu, Qing Liu, Chuiyan Qiu, Haiyan Yin, Jun Lyu
BACKGROUND: Acute pancreatitis (AP) is a common gastrointestinal disease in which infection is a serious complication. Understanding its bacterial spectrum and antibiotic resistance is of great significance for treatment. OBJECTIVE: This retrospective study analyzed the Medical Information Mart for Intensive Care database with the aim of identifying the distribution characteristics of pathogenic bacteria in AP patients. METHODS: First, 2089 AP patients were classified and analyzed statistically according to culture results...
February 2023: Digestive Diseases and Sciences
https://read.qxmd.com/read/36509643/acute-pancreatitis-is-characterized-by-generalized-intestinal-barrier-dysfunction-in-early-stage
#34
JOURNAL ARTICLE
Samagra Agarwal, Pooja Goswami, Shekhar Poudel, Deepak Gunjan, Namrata Singh, Rajni Yadav, Umesh Kumar, Gaurav Pandey, Anoop Saraya
BACKGROUND AND AIMS: The role of intestinal-barrier in acute pancreatitis(AP) is poorly understood. We aimed to assess structural and functional changes in the intestinal-barrier in patients with early AP (time from onset<2 weeks) and the effect of enteral nutrition on them. METHODS: In this prospective observational study, patients with early AP not on enteral nutrition were compared with controls for baseline intestinal-permeability(lactulose: mannitol ratio(L:M)), endotoxinemia(serum IgM/IgG anti-endotoxin antibodies), bacterial-translocation(serum bacterial 16S rRNA) and duodenal epithelial tight-junction structure by immunohistochemistry(IHC) for tight-junction proteins(claudin-2,-3,-4, zonula occludens-1(ZO1), junctional adhesion molecule(JAM) and occludin) and electron microscopy...
January 2023: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://read.qxmd.com/read/36504520/diagnosis-severity-stratification-and-management-of-adult-acute-pancreatitis-current-evidence-and-controversies
#35
REVIEW
Kai Siang Chan, Vishal G Shelat
Acute pancreatitis (AP) is a disease spectrum ranging from mild to severe with an unpredictable natural course. Majority of cases (80%) are mild and self-limiting. However, severe AP (SAP) has a mortality risk of up to 30%. Establishing aetiology and risk stratification are essential pillars of clinical care. Idiopathic AP is a diagnosis of exclusion which should only be used after extended investigations fail to identify a cause. Tenets of management of mild AP include pain control and management of aetiology to prevent recurrence...
November 27, 2022: World Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/36425407/evidence-based-approach-to-the-surgical-management-of-acute-pancreatitis
#36
REVIEW
Alex James Sagar, Majid Khan, Niteen Tapuria
Background  Acute pancreatitis is a significant challenge to health services. Remarkable progress has been made in the last decade in optimizing its management. Methods  This review is a comprehensive assessment of 7 guidelines employed in current clinical practice with an appraisal of the underlying evidence, including 15 meta-analyses/systematic reviews, 16 randomized controlled trials, and 31 cohort studies. Results  Key tenets of early management of acute pancreatitis include severity stratification based on the degree of organ failure and early goal-directed fluid resuscitation...
October 2022: Surgery Journal
https://read.qxmd.com/read/36364832/nutritional-support-in-pancreatic-diseases
#37
REVIEW
Pablo Cañamares-Orbís, Guillermo García-Rayado, Enrique Alfaro-Almajano
This review summarizes the main pancreatic diseases from a nutritional approach. Nutrition is a cornerstone of pancreatic disease and is sometimes undervalued. An early identification of malnutrition is the first step in maintaining an adequate nutritional status in acute pancreatitis, chronic pancreatitis and pancreatic cancer. Following a proper diet is a pillar in the treatment of pancreatic diseases and, often, nutritional counseling becomes essential. In addition, some patients will require oral nutritional supplements and fat-soluble vitamins to combat certain deficiencies...
October 31, 2022: Nutrients
https://read.qxmd.com/read/36152590/enteral-nutrition-for-children-with-acute-leukemia-related-pancreatitis
#38
JOURNAL ARTICLE
Da Li, Ying Wu, Yuanyuan Zhang, Wei Lin, Jia Fan, Peijing Qi, Huyong Zheng, Jie Yan, Ruidong Zhang
OBJECTIVE: Pancreatitis in children with acute lymphoblastic leukemia and acute myeloid leukemia may cause discontinuation of chemotherapy, thus adversely affecting treatment outcomes. Enteral nutrition (EN) is recommended for acute pancreatitis. The optimal use of EN for leukemia-related pancreatitis is under debate. The aim of this study was to determine the clinical efficacy of EN for children with leukemia-related pancreatitis. METHODS: Medical records of 53 children with characteristics of leukemia-related pancreatitis were abstracted retrospectively...
2022: Nutrition
https://read.qxmd.com/read/36074968/enteral-nutrition-preparations-for-blood-glucose-variability-and-prognosis-for-severe-acute-pancreatitis-with-stress-hyperglycemia
#39
JOURNAL ARTICLE
Hong Zhang, Lei Li, Jingyi Wu, Wen Xu, Jun Wu
Context: Severe acute pancreatitis (SAP) is a common critical illness, and stress hyperglycemia is the greatest independent risk factor for poor prognoses in critically ill patients. Enteral nutrition can not only provide an essential energy source for the body and improve a patient's intestinal micro-ecology but also can play a critical role in blood glucose management, especially for blood glucose variability. Objective: The study intended to investigate the effects of different enteral nutrition preparations, including a slow-release starch, on blood glucose variability, nutritional status, inflammatory indexes, and prognosis for patients with SAP with stress hyperglycemia...
September 9, 2022: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/36074322/acute-pancreatitis-diagnosis-and-treatment
#40
REVIEW
Peter Szatmary, Tassos Grammatikopoulos, Wenhao Cai, Wei Huang, Rajarshi Mukherjee, Chris Halloran, Georg Beyer, Robert Sutton
Acute pancreatitis is a common indication for hospital admission, increasing in incidence, including in children, pregnancy and the elderly. Moderately severe acute pancreatitis with fluid and/or necrotic collections causes substantial morbidity, and severe disease with persistent organ failure causes significant mortality. The diagnosis requires two of upper abdominal pain, amylase/lipase ≥ 3 ×upper limit of normal, and/or cross-sectional imaging findings. Gallstones and ethanol predominate while hypertriglyceridaemia and drugs are notable among many causes...
September 8, 2022: Drugs
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