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Clinical manifestations catheter related bloodstream infections

Akihiro Sato, Itaru Nakamura, Hiroaki Fujita, Ayaka Tsukimori, Takehito Kobayashi, Shinji Fukushima, Takeshi Fujii, Tetsuya Matsumoto
BACKGROUND: The purpose of this study was to identify the clinical characteristics and outcomes of peripheral vascular catheter-related bloodstream infections (PVC-BSIs) and determine the risk of severe complications or death. METHODS: We performed a retrospective observational study from June 2010 to April 2015 at two regional university-affiliated hospitals in Tokyo. We studied the clinical manifestations, underlying diseases, laboratory results, treatment methods, recurrence rates, and complications in 62 hospitalized patients diagnosed with PVC-BSIs by positive blood cultures...
June 17, 2017: BMC Infectious Diseases
Teresa Jackowska, Katarzyna Pawlik
INTRODUCTION: Patients pediatric wards are particularly at risk of nosocomial infections. Therefore, the newest principles of prevention of infections should be implemented and monitored. AIM: 1) to determine the prevalence, etiology and clinical manifestations of nosocomial infections in hospitalized patients; 2) to evaluate the effectiveness of procedures that aim at preventing hospital rotavirus infections and catheter-related bloodstream infections; 3) to analyse the incidence of flu among staff in two consecutive seasons of the epidemic influenza H1N1 (2009/2010 and 2010/2011); 4) to promote vaccinations of the medical staff...
April 2015: Developmental Period Medicine
Hung-Jen Tang, Chih-Cheng Lai, Hsin-Lan Lin, Chien-Ming Chao
AIM: This study is conducted to investigate the clinical characteristics of patients with bacteremia caused by Aeromonas species. MATERIALS AND METHODS: Patients with bacteremia caused by Aeromonas species during the period 2009 to 2013 were identified from a computerized database of a regional hospital in southern Taiwan. The medical records of these patients were retrospectively reviewed. RESULTS: A total of 91 patients with bacteremia due to Aeromonas species were identified...
2014: PloS One
Shannon Kasperbauer, Gwen Huitt
Nontuberculous mycobacteria represent a vast group of environmental organisms that have the potential to cause disease in humans. Unlike tuberculosis, these organisms are not known to be transmitted from human to human. The most common clinical presentation is pulmonary disease. Approximately 10% of infections manifest as extrapulmonary disease. The portals of entry are the respiratory tract, gastrointestinal tract, or direct inoculation via trauma or an invasive procedure. Like tuberculosis, the nontuberculous mycobacteria have the potential to infect any organ system given the opportunity in an immunocompromised host...
February 2013: Seminars in Respiratory and Critical Care Medicine
Chetan Naik, Hrishikesh Kulkarni, Ali Darabi, Nitin Bhanot
Ochrobactrum anthropi, a Gram-negative bacillus, is an unusual human pathogen. It has been implicated primarily in catheter-related bloodstream infections. Sporadic cases of infection at other body sites have been reported. Pneumonia, however, is an exceedingly rare clinical manifestation; only one case has been reported in the medical literature so far. We present another case of lower respiratory tract infection secondary to O. anthropi in a patient who was critically ill, but recovered with a favorable outcome...
February 2013: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
M Picardi, S Pagliuca, F Chiurazzi, D Iula, M Catania, F Rossano, F Pane
BACKGROUND: Septic thrombophlebitis increases patient morbidity and mortality following metastatic infections, pulmonary emboli, and/or septic shock. Central venous catheter (CVC) removal for occult septic thrombophlebitis challenges current strategy in neutropenic patients. PATIENTS AND METHODS: We prospectively evaluated infection-related mortality in 100 acute leukemia patients, with CVC-related bloodstream infection (CRBSI) after chemotherapy, who systematically underwent ultrasonography to identify the need for catheter removal...
August 2012: Annals of Oncology: Official Journal of the European Society for Medical Oncology
Deborah Tomlinson, Leonard A Mermel, Marie-Chantal Ethier, Anne Matlow, Biljana Gillmeister, Lillian Sung
The objective of this review was to determine whether consistent definitions were used in published studies of bloodstream infections due to central venous catheters in patients with cancer (ie, catheter-related or catheter-associated bloodstream infections). Review of 191 studies reporting catheter-related or catheter-associated bloodstream infections in patients with cancer revealed a lack of uniformity in these definitions. We grouped definitions by type, with 39 articles failing to cite or report a definition...
October 2011: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Jiun-Nong Lin, Chung-Hsu Lai, Yen-Hsu Chen, Hsing-Lin Lin, Chun-Kai Huang, Wei-Fang Chen, Jiun-Ling Wang, Hsing-Chun Chung, Shiou-Haur Liang, Hsi-Hsun Lin
BACKGROUND/PURPOSE: Sphingomonas paucimobilis is a glucose-nonfermenting Gram-negative bacillus that is widely distributed in both natural environment and hospitals. Various infections in humans have been reported, but most have been limited to sporadic case reports. The aim of this study was to describe the clinical characteristics and manifestations of S. paucimobilis bacteremia. We also reviewed the literature on S. paucimobilis bacteremia. METHODS: Cases of S...
February 2010: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
Issam Raad, Hend Hanna, Dennis Maki
Indwelling vascular catheters are a leading source of bloodstream infections in critically ill patients and cancer patients. Because clinical diagnostic criteria are either insensitive or non-specific, such infections are often overdiagnosed, resulting in unnecessary and wasteful removal of the catheter. Catheter-sparing diagnostic methods, such as differential quantitative blood cultures and time to positivity have emerged as reliable diagnostic techniques. Novel preventive strategies include cutaneous antisepsis, maximum sterile barrier, use of antimicrobial catheters, and antimicrobial catheter lock solution...
October 2007: Lancet Infectious Diseases
Rania Hanna, Issam I Raad
Catheter-related bloodstream infection is a potentially serious condition with a mortality rate of 12% to 25%. Catheter-related bacteremia is difficult to diagnose, and clinical manifestations of the condition have proved to be unspecific and often inconclusive. Microbiologic techniques to diagnose catheter-related bloodstream infection have been developed, some of which require catheter removal whereas others do not. Differential time to positivity has demonstrated marked accuracy and practicality as it allows the catheter to remain in place...
November 2005: Current Infectious Disease Reports
Ioannis Germanakis, Athanasia Christidou, Emmanouil Galanakis, Iraklis Kyriakakis, Yiannis Tselentis, Maria Kalmanti
BACKGROUND: Paired quantitative and qualitative blood cultures have been introduced for the diagnosis of catheter-related bloodstream infections (CRBI) with the catheter in situ. The aim of the study was to compare the diagnostic performance and the prognostic value of the two methods in the evaluation of febrile episodes without an apparent source in children with cancer. PROCEDURE: During a 4-year period, in every febrile episode without an apparent focus, blood was drawn simultaneously from the catheter lumen and a peripheral vein in order to perform paired quantitative (Isolator) as well as qualitative (BacT/Alert) blood cultures...
December 2005: Pediatric Blood & Cancer
Fabio Paglialonga, Susanna Esposito, Alberto Edefonti, Nicola Principi
Infectious complications of the central venous catheter (CVC) are a major source of morbidity among children treated with hemodialysis (HD), with catheter-related bloodstream infections (CRBSI) being the most important clinical manifestations. As only a few studies of children on HD have been published, the management of CVC-related infections in this population is mainly based on data derived from adults or occasionally from children not affected by end-stage renal disease (ESRD). The aim of this review is to discuss current knowledge concerning the epidemiology, prevention, and treatment of catheter-related infections in children on HD...
December 2004: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
Janet Pettit
Peripherally inserted central catheters (PICCs) are frequently placed in neonates to optimize nutrition and provide stable infusions of critical medications into the central vascular system. PICCs have been associated with a number of device-specific complications that can manifest during insertion, while the line is indwelling, and/or after the removal of the line. The first article of this series in Focus on the Physical, titled "Assessment of Infants With Peripherally Inserted Central Catheters: Part I. Detecting the Most Frequently Occurring Complications," presented assessment strategies to detect common complications such as catheter occlusions and catheter-related bloodstream infections...
February 2003: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
M B Salzman, L G Rubin
Vascular catheter-related infection is an important cause of mortality and morbidity in hospitalized patients. The mean incidence of catheter-related bloodstream infection in hospitalized pediatric patients is 2.4 episodes per 1,000 days. Totally implantable central venous catheters may be associated with a lower risk of infection. Coagulase-negative staphylococci are the predominant cause and account for about one third of episodes of catheter-related bloodstream infection. The diagnosis of catheter-related bloodstream infection is often difficult because there are frequently no signs of inflammation around the catheter...
1995: Advances in Pediatric Infectious Diseases
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