keyword
MENU ▼
Read by QxMD icon Read
search

anaphylactic reaction

keyword
https://www.readbyqxmd.com/read/29331065/component-resolved-diagnostics-to-direct-in-venom-immunotherapy-important-steps-towards-precision-medicine
#1
Simon Blank, Maria Beatrice Bilò, Markus Ollert
Stings of Hymenoptera can induce IgE-mediated systemic and even fatal allergic reactions. Venom-specific immunotherapy (VIT) is the only disease-modifying and curative treatment of venom allergy. However, choosing the correct venom for VIT represents a necessary prerequisite for efficient protection against further anaphylactic sting reactions after VIT. In the past, therapeutic decisions based on the measurement of specific IgE (sIgE) levels to whole venom extracts were not always straightforward, especially when the patient was not able to identify the culprit insect...
January 13, 2018: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29319891/teicoplanin-anaphylaxis-associated-with-surgical-prophylaxis
#2
Tariq Azamgarhi, Ashik Shah, Simon Warren
BACKGROUND: The rate of true anaphylaxis to teicoplanin is currently unknown. METHODS: A case-series including all suspected anaphylactic reactions attributed to teicoplanin anaphylaxis within a single institution over a 29-month period were categorised according to the probability of true IgE mediated anaphylaxis using previously published criteria. The number of patients who receive Teicoplanin was determined and used to calculate the rate of IgE mediated anaphylaxis...
January 10, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29318637/factors-increasing-the-risk-for-a-severe-reaction-in-anaphylaxis-an-analysis-of-data-from-the-european-anaphylaxis-registry
#3
Margitta Worm, Wojciech Francuzik, Jean-Marie Renaudin, Maria Beatrice Bilo, Victòria Cardona, Kathrin Scherer Hofmeier, Alice Köhli, Andrea Bauer, George Christoff, Ewa Cichocka-Jarosz, Thomas Hawranek, Jonathan O'B Hourihane, Lars Lange, Vera Mahler, Antonella Muraro, Nikolaos G Papadopoulos, Claudia Pföhler, Iwona Poziomkowska-Gęsicka, Franziska Ruëff, Thomas Spindler, Regina Treudler, Montserrat Fernandez-Rivas, Sabine Dölle
BACKGROUND: Preventive measures to decrease the frequency and intensity of anaphylactic events are essential to provide optimal care for allergic patients. Aggravating factors may trigger or increase the severity of anaphylaxis and therefore need to be recognized and avoided. OBJECTIVE: To identify and prioritize factors associated with an increased risk of developing severe anaphylaxis. METHODS: Data from the Anaphylaxis Registry (122 centers in 11 European countries) was used in logistic regression models considering existing severity grading systems, elicitors, and symptoms to identify the relative risk of factors on the severity of anaphylaxis...
January 10, 2018: Allergy
https://www.readbyqxmd.com/read/29316984/coronary-artery-spasm-due-to-intravenous-atropine-infusion-in-a-child-possible-kounis-syndrome
#4
Ana Castellano-Martinez, Moises Rodriguez-Gonzalez
Coronary vasospasm can result from silent myocardial ischaemia to sudden death. There are many precipitant factors including different pharmacological agents. Kounis syndrome is defined by acute coronary syndromes associated with anaphylactic or anaphylactoid reactions. We report, to the best of our knowledge, the first paediatric case of Kounis syndrome due to intravenous atropine.
January 10, 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29300005/food-allergy
#5
REVIEW
Harald Renz, Katrina J Allen, Scott H Sicherer, Hugh A Sampson, Gideon Lack, Kirsten Beyer, Hans C Oettgen
Food allergies manifest in a variety of clinical conditions within the gastrointestinal tract, skin and lungs, with the most dramatic and sometimes fatal manifestation being anaphylactic shock. Major progress has been made in basic, translational and clinical research, leading to a better understanding of the underlying immunological mechanisms that lead to the breakdown of clinical and immunological tolerance against food antigens, which can result in either immunoglobulin E (IgE)-mediated reactions or non-IgE-mediated reactions...
January 4, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29284348/severe-anaphylactic-reaction-following-anti-thymocyte-globulin-administration-in-a-pediatric-stem-cell-transplantation-patient
#6
Tiene Bauters, Victoria Bordon, Jef Willems, Bram De Wilde, Geneviève Laureys
We present a case of a severe reaction after anti-thymocyte administration despite premedication and strict adherence to administration guidelines during the conditioning regimen. Due to the severity of the adverse drug reaction, we believe that this case should be reported.
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29280268/obstetricians-awareness-associated-with-better-outcomes
#7
David A Eschenbach
Doctors are charged to treat disease while causing no harm. An anaphylactic reaction is the furthest from our mind in dispensing medication. However, an anaphylactic reaction to medication can cause serious harm and even death as outlined by McCall et al. (1). This report is a well-conducted and important prospective study. First, their strict definition of anaphylaxis included only patients with a life threatening airway problem, a life threatening breathing problem or a significant circulation problem. Second, they also used a semi-active surveillance system to both identify and report anaphylaxis monthly at individual hospitals...
December 27, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29277702/the-transcription-factors-gata2-and-mitf-regulate-hdc-gene-expression-in-mast-cells-and-are-required-for-ige-mast-cell-mediated-anaphylaxis
#8
Yapeng Li, Bing Liu, Laura Harmacek, Zijie Long, Jinyi Liang, Kara Lukin, Sonia M Leach, Brian O'Connor, Anthony N Gerber, James Hagman, Axel Roers, Fred D Finkelman, Hua Huang
BACKGROUND: Histamine is a critical mediator of IgE/mast cell-mediated anaphylaxis. Histamine is synthesized by decarboxylating the amino acid histidine, a reaction catalyzed by the Hdc-gene encoded enzyme histidine decarboxylase. However, regulation of the Hdc gene in mast cells is poorly understood. OBJECTIVE: We sought to investigate the in vivo regulation of IgE/mast cell mediated anaphylaxis by transcription factors GATA2 and MITF and the mechanisms by which GATA2 and MITF regulate Hdc gene expression in mouse and human mast cells...
December 22, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29274313/mitral-ring-extraction-due-to-nickel-allergy
#9
Carlos Dominguez-Massa, Ana M Bel-Minguez, Manuel Perez-Guillen, Alberto Berbel-Bonillo, Fernando Hornero-Sos
The incidence of allergic reactions due to mechanical prosthesis or rings is not well established. We report the case of a 56-year-old male patient who presented a persistent urticarial rash and anaphylactic shock after mitral valve repair surgery. Prick skin tests were positive for nickel. After removing the nucleus from the mitral annulus, the urticarial clinic disappeared.
December 20, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29258788/anaphylactic-reactions-after-discontinuation-of-hymenoptera-venom-immunotherapy-a-clonal-mast-cell-disorder-should-be-suspected
#10
Patrizia Bonadonna, Roberta Zanotti, Mauro Pagani, Massimiliano Bonifacio, Luigi Scaffidi, Elisa Olivieri, Maurizio Franchini, Federico Reccardini, Maria Teresa Costantino, Chiara Roncallo, Marina Mauro, Elisa Boni, Fabio Lodi Rizzini, Maria Beatrice Bilò, Anna Rosaria Marcarelli, Giovanni Passalacqua
BACKGROUND: Up to 75% of patients with severe anaphylactic reactions after Hymenoptera sting are at risk of further severe reactions if re-stung. Venom immunotherapy (VIT) is highly effective in protecting individuals with ascertained Hymenoptera venom allergy (HVA) and previous severe reactions. After a 3- to 5-year VIT course, most patients remain protected after VIT discontinuation. Otherwise, a lifelong treatment should be considered in high-risk patients (eg, in mastocytosis). Several case reports evidenced that patients with mastocytosis and HVA, although protected during VIT, can re-experience severe and sometimes fatal reactions after VIT discontinuation...
December 16, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29238519/how-to-manage-anaphylaxis-in-primary-care
#11
REVIEW
Alberto Alvarez-Perea, Luciana Kase Tanno, María L Baeza
Anaphylaxis is defined as a severe life-threatening generalized or systemic hypersensitivity reaction characterized by rapidly developing airway and/or circulation problems. It presents with very different combinations of symptoms and apparently mild signs and can progress to fatal anaphylactic shock unpredictably. The difficulty in recognizing anaphylaxis is due, in part, to the variability of diagnostic criteria, which in turn leads to a delay in administration of appropriate treatment, thus increasing the risk of death...
2017: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/29233461/long-term-safety-of-subcutaneous-immunotherapy-with-to-204-in-japanese-patients-with-house-dust-mite-induced-allergic-rhinitis-and-allergic-bronchial-asthma-multicenter-open-label-clinical-trial
#12
Takao Fujisawa, Terufumi Shimoda, Keisuke Masuyama, Kimihiro Okubo, Kohei Honda, Mitsuhiro Okano, Toshio Katsunuma, Atsuo Urisu, Yasuto Kondo, Hiroshi Odajima, Kazuyuki Kurihara, Makoto Nagata, Masami Taniguchi, Shoichiro Taniuchi, Satoru Doi, Tomoshige Matsumoto, Shoji Hashimoto, Akihiko Tanaka, Kensuke Natsui, Nahoko Abe, Hideki Ozaki
BACKGROUND: To evaluate the long-term safety of subcutaneous immunotherapy with TO-204, a standardized house dust mite (HDM) allergen extracts, we conducted a multicenter, open label clinical trial. METHODS: Japanese patients aged 5-65 years were eligible for the study, if they had HDM-induced allergic rhinitis (AR), allergic bronchial asthma (BA), or both. TO-204 was administered in a dose titration scheme, and the maintenance dose was determined according to the predefined criteria...
December 7, 2017: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29214012/evidence-of-the-efficacy-and-safety-of-house-dust-mite-subcutaneous-immunotherapy-in-elderly-allergic-rhinitis-patients-a-randomized-double-blind-placebo-controlled-trial
#13
Andrzej Bożek, Krzysztof Kołodziejczyk, Renata Kozłowska, Giorgio Walter Canonica
Background: Allergen specific immunotherapy (AIT) in elderly patients is controversial, and there is still little evidence supporting the safety and efficacy of this treatment in this population. The study objective was to evaluate the safety and efficacy of AIT for house dust mite allergens in patients over 65 years of age with allergic rhinitis (AR) and a documented allergy to house dust mites. The primary endpoint was the change from baseline in the mean average adjusted symptom score (AAdSS) and the total combined rhinitis score (TCRS) difference in the least square means for the label compared to placebo...
2017: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/29210337/death-following-ceftazidime-induced-kounis-syndrome
#14
Idg Kitulwatte, S Gangahawatte, Ulms Perera, Pas Edirisinghe
Kounis syndrome, also known as allergic myocardial infarction or allergic angina syndrome, coincides with chest pain and allergic reactions. It involves the activation of interrelated inflammatory cells following allergic, anaphylactic or anaphylactoid insults. We report a case of Kounis syndrome complicated by an injection of ceftazidime. A 52-year-old man developed shortness of breath and hypotension, leading to immediate unconsciousness, after a ceftazidime injection. Despite intensive care management, he showed no improvement and died approximately 19 h after ceftazidime administration...
December 2017: Medico-legal Journal
https://www.readbyqxmd.com/read/29210121/proanthocyanidin-rich-pinus-radiata-bark-extract-inhibits-mast-cell-mediated-anaphylaxis-like-reactions
#15
Yun Ho Choi, Chang Ho Song, Sung Phil Mun
Mast cells play a critical role in the effector phase of immediate hypersensitivity and allergic reactions. Pinus radiata bark extract exerts multiple biological effects and exhibits immunomodulatory and antioxidant properties. However, its role in mast cell-mediated anaphylactic reactions has not been thoroughly investigated. In this study, we examined the effects of proanthocyanidin-rich water extract (PAWE) isolated from P. radiata bark on compound 48/80-induced or antidinitrophenyl (DNP) immunoglobulin E (IgE)-mediated anaphylaxis-like reactions in vivo...
December 6, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29203045/anaphylactic-shock-with-an-ultrasound-contrast-agent
#16
S Coudray, C Fabre, I Aichoun, A Perez-Martin
Echo contrast agents, such as SonoVue®, (Bracco, Milan, Italy) are often used to enhance diagnosis. Although their use is safe, some rare side effects could be severe or even fatal. We are reporting a case of severe systemic allergic reaction after infusion of SonoVue®. After a brief review of the literature, the aim of this paper is to draw attention to this risk and recall the safety instructions coming with the use of ultrasound contrast agents.
December 2017: Journal de Médecine Vasculaire
https://www.readbyqxmd.com/read/29201066/anaphylactic-shock-following-castor-bean-contact-a-case-report
#17
Y Coattrenec, D Jaques, P Jandus, T Harr, D Spoerl
Background: The castor bean plant, Ricinus communis, is known to have allergenic and toxic properties. Castor bean allergy has been described mainly as an occupational inhalation allergy in laboratory workers, in persons working in oil processing mills or in agricultural industry. So far, only one case of anaphylactic reaction due to castor bean sensitization confirmed by specific IgE has been described in literature. Case presentation: A 30-year-old woman presented to the emergency room with severe angioedema followed by urticaria, hypotension and tachycardia...
2017: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/29189183/ige-sensitization-to-anisakis-simplex-and-diet-recommendation-in-a-polycentric-study
#18
Rosalba Buquicchio, Maria Teresa Ventura, Pier Luigi Traetta, Saverio Nenna, Giuseppe Iadarola, Thea Magrone
BACKGROUND: Allergy to Anisakis simplex (s.) is spreading due to the increased consumption of raw, smoked or marinated fish. In humans, Anisakis s. can directly attack the gastrointestinal mucosa, provoking a parasitosis known as anisakiasis, or giving rise to the formation of IgE and, finally, inducing IgE-mediated reactions like urticaria, angioedema and anaphylactic shock. During recent years, a dietary approach to Anisakis s. infestation has also been addressed. METHODS: A total of 620 patients with urticaria, angioedema, or both and a history of anaphylaxis following consumption of raw, smoked or marinated fish were recruited, evaluated for specific IgE levels to Anisakis s...
November 29, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/29180995/b-cell-intrinsic-mechanisms-constraining-ige-memory
#19
REVIEW
Brice Laffleur, Orianne Debeaupuis, Zeinab Dalloul, Michel Cogné
Memory B cells and long-lived plasma cells are key elements of adaptive humoral immunity. Regardless of the immunoglobulin class produced, these cells can ensure long-lasting protection but also long-lasting immunopathology, thus requiring tight regulation of their generation and survival. Among all antibody classes, this is especially true for IgE, which stands as the most potent, and can trigger dramatic inflammatory reactions even when present in minute amounts. IgE responses and memory crucially protect against parasites and toxic components of venoms, conferring selective advantages and explaining their conservation in all mammalian species despite a parallel broad spectrum of IgE-mediated immunopathology...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29171912/concomitant-sensitization-to-legumin-fag-e-2-and-fag-e-5-predicts-buckwheat-allergy
#20
S Geiselhart, C Nagl, P Dubiela, A C Pedersen, M Bublin, C Radauer, C Bindslev-Jensen, K Hoffmann-Sommergruber, C G Mortz
BACKGROUND: Buckwheat (Fagopyrum esculentum) has become increasingly popular as a healthy food in Europe. However, for sensitized individuals, consumption can cause anaphylactic reactions. The aim of this study was to identify individual well-characterized buckwheat allergens for component resolved diagnosis. METHODS: Patients were selected by positive skin prick test to buckwheat and divided into two groups: (1) sensitized to buckwheat without clinical symptoms and (2) buckwheat allergy...
November 24, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
keyword
keyword
33953
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"