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https://www.readbyqxmd.com/read/29679763/leaving-the-nest-improving-food-allergy-management-on-college-campuses
#1
Ashley A Dyer, Amy O'Keefe, Madeleine K Kanaley, Lauren Kao, Ruchi S Gupta
BACKGROUND: The transition from adolescence to young adulthood marks a developmental period where responsibility for management of chronic conditions such as food allergy shifts from the caregiver to the young adult. Fatal food-induced anaphylaxis is most common among adolescents and young adults. However, colleges are currently not well-positioned to provide integrated support for students with food allergies. OBJECTIVE: The study objective was to explore the systems, structures, and policies that currently support students with food allergies at college, assess unmet needs, and develop pilot interventions through the use of patient-centered design processes...
April 18, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29676818/new-insights-into-the-phenotypes-of-atopic-dermatitis-linked-with-allergies-and-asthma-in-children-an-overview
#2
F Amat, A Soria, P Tallon, M Bourgoin-Heck, N Lambert, A Deschildre, J Just
Atopic dermatitis (AD) is a complex disease with multiple causes and complex mechanistic pathways according to age of onset, severity of the illness, ethnic modifiers, response to therapy, and triggers. A group of difficult-to-manage patients characterized by early-onset AD and severe lifelong disease associated with allergic asthma and/or food allergy, has been identified. In this paper, we focus on these severe phenotypes, analyzing their links with other atopic comorbidities, and taking into account the results from recent cohort studies and meta-analyses...
April 20, 2018: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29676439/oral-and-sublingual-immunotherapy-for-egg-allergy
#3
REVIEW
Olga Romantsik, Maria Angela Tosca, Simona Zappettini, Maria Grazia Calevo
BACKGROUND: Clinical egg allergy is a common food allergy. Current management relies upon strict allergen avoidance. Oral immunotherapy might be an optional treatment, through desensitization to egg allergen. OBJECTIVES: To determine the efficacy and safety of oral and sublingual immunotherapy in children and adults with immunoglobulin E (IgE)-mediated egg allergy as compared to a placebo treatment or an avoidance strategy. SEARCH METHODS: We searched 13 databases for journal articles, conference proceedings, theses and trials registers using a combination of subject headings and text words (last search 31 March 2017)...
April 20, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29676066/allergen-specific-immunotherapies-for-food-allergy
#4
REVIEW
Elizabeth Feuille, Anna Nowak-Wegrzyn
With rising prevalence of food allergy (FA), allergen-specific immunotherapy (AIT) for FA has become an active area of research in recent years. In AIT, incrementally increasing doses of inciting allergen are given with the goal to increase tolerance, initially through desensitization, which relies on regular exposure to allergen. With prolonged therapy in some subjects, AIT may induce sustained unresponsiveness, in which tolerance is retained after a period of allergen avoidance. Methods of AIT currently under study in humans include oral, sublingual, epicutaneous, and subcutaneous delivery of modified allergenic protein, as well as via DNA-based vaccines encoding allergen with lysosomal-associated membrane protein I...
May 2018: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/29675865/allergen-immunotherapy-in-people-dogs-cats-and-horses-differences-similarities-and-research-needs
#5
R S Mueller, E Jensen-Jarolim, F Roth-Walter, E Marti, J Janda, A A Seida, D DeBoer
In human patients with seasonal allergic rhinoconjunctivitis sensitized to grass pollen, the first successful allergen immunotherapy (AIT) was reported in 1911. Today, immunotherapy is an accepted treatment for allergic asthma, allergic rhinitis and hypersensitivities to insect venom. AIT is also used for atopic dermatitis and recently for food allergy. Subcutaneous, epicutaneous, intralymphatic, oral and sublingual protocols of AIT exist. In animals, most data are available in dogs where subcutaneous AIT is an accepted treatment for atopic dermatitis...
April 19, 2018: Allergy
https://www.readbyqxmd.com/read/29670991/food-labelling-regulations-and-public-health-implications
#6
V Marcotrigiano, C Lanzilotti, D Rondinone, O De Giglio, G Caggiano, G Diella, G B Orsi, M T Montagna, C Napoli
Legislators have implemented policies to improve food labelling to protect consumers and to make the presentation of ingredients and nutritional information more transparent. Proper food labelling allows consumers who may suffer from food allergies or intolerances to know exactly what ingredients a product contains, and it also helps them make more informed health and nutrition choices. This paper deals with the most current European and Italian legislation on food labelling, actions taken in non-EU countries to increase health choices, and the expected impact on Public Health...
May 2018: Annali di Igiene: Medicina Preventiva e di Comunità
https://www.readbyqxmd.com/read/29669337/search-for-a-novel-allergen-in-hen-s-egg-allergy-using-an-ige-immunoblotting-assay
#7
Kazuyuki Sogawa, Yuria Takahashi, Yui Shibata, Mamoru Satoh, Yoshio Kodera, Fumio Nomura, Toshio Tanaka, Hironori Sato, Fumiya Yamaide, Taiji Nakano, Kazuhiko Iwahashi, Yoshiko Sugita-Konishi, Akinori Shimada, Naoki Shimojo
BACKGROUND: Food allergy is a serious health issue affecting roughly 4% of children, with a substantial effect on quality of life. Chicken egg allergy is frequently observed in infants. Therefore, some of them have to exclude hen's eggs from their daily diet to avoid allergenic symptoms. Hen's egg is composed of 2 soluble parts; one is egg white, which has been characterized as the major source of allergenicity, while the other is egg yolk, which is estimated as a miner source. Only 2 allergens from egg yolk, α-livetin (Gal d 5) and YGP42 (Gal d 6), have been described to date...
April 18, 2018: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/29666678/allergic-rhinitis-in-relation-to-food-allergies-pointers-to-future-research
#8
Rashid Al-Abri, Asdaf S Al-Amri, Zaina Al-Dhahli, Ajoy M Varghese
Allergic rhinitis is a ubiquitous type of allergic reaction which results in significant costs to affected patients and their families. Although allergic rhinitis can coexist with other atopic conditions, the role of food allergies in the development of allergic rhinitis has not been well studied. This article explores relevant literature on this subject in order to identify gaps in the available body of knowledge and elucidate scope for further research.
February 2018: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29662290/extra-intestinal-manifestations-of-non-celiac-gluten-sensitivity-an-expanding-paradigm
#9
REVIEW
Giuseppe Losurdo, Mariabeatrice Principi, Andrea Iannone, Annacinzia Amoruso, Enzo Ierardi, Alfredo Di Leo, Michele Barone
Non celiac gluten sensitivity (NCGS) is a syndrome characterized by a cohort of symptoms related to the ingestion of gluten-containing food in subjects who are not affected by celiac disease (CD) or wheat allergy. The possibility of systemic manifestations in this condition has been suggested by some reports. In most cases they are characterized by vague symptoms such as 'foggy mind', headache, fatigue, joint and muscle pain, leg or arm numbness even if more specific complaints have been described. NCGS has an immune-related background...
April 14, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29661744/allergy-to-limanda-aspera-yellowfin-sole-report-of-a-case-of-food-allergy-in-a-child
#10
M Viñas, F Pineda, A Izquierdo-Domínguez, M Castillo, M J Castillo, N Hernández, B Delavalle, J Barrena, M Ibero
No abstract text is available yet for this article.
April 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29660855/the-impact-of-oral-food-challenges-for-food-allergy-on-quality-of-life-a-systematic-review
#11
Hannah M Kansen, Thuy-My Le, Yolanda Meijer, Bertine M J Flokstra-de Blok, Paco M J Welsing, Cornelis K van der Ent, André C Knulst, Francine C van Erp
BACKGROUND: Food allergy significantly impairs health-related quality of life (HRQL). Currently, it is still unknown whether diagnostic interventions for food allergy improve HRQL. We aim to assess the impact of diagnostic interventions for food allergy on HRQL. METHODS: A systematic search was performed in MEDLINE, Embase, Cochrane Library and CINAHL focused on patients with a (suspected) food allergy who underwent diagnostic interventions (i.e. skin prick test, specific IgE or oral food challenges (OFC)), and in whom HRQL was assessed...
April 16, 2018: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29656306/oral-and-sublingual-immunotherapy-for-treatment-of-ige-mediated-food-allergy
#12
REVIEW
Amy M Scurlock
Development of active therapies for IgE-mediated food allergy is a critical action step toward alleviating the adverse medical, psychosocial, and economic burdens on affected patients and families. Significant progress has been observed specifically in the application of single-allergen oral and sublingual immunotherapy for treatment of IgE-mediated food allergy, with emphasis on milk, egg, and peanut as the primary allergens. Oral immunotherapy (OIT) has demonstrated efficacy in promoting immunomodulatory effects that lead to the clinical outcome of desensitization, defined as reduced reactivity while on active OIT, in the majority of treated individuals; however, achievement of sustained unresponsiveness following cessation of therapy has been observed in a smaller subset of treated subjects...
April 14, 2018: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/29656088/-ne-nnipadua-mmpe-the-body-hates-it-exploring-the-lived-experience-of-food-allergy-in-sub-saharan-africa
#13
George A Atiim, Susan J Elliott, Ann E Clarke
Allergic diseases have closely followed the rise of non-communicable diseases (NCDs) especially in western societies. As prevalence of NCD is increasing in sub-Saharan Africa (SSA), researchers are hinting that the same future may hold for (food) allergic disease in this world region. Already, researchers are beginning to record prevalence, though with little attention to the social experience of individuals and parents with food allergic children. This paper presents the first qualitative analysis of the daily realities of adults and parents of children with allergies in SSA using Ghana as a case study...
March 23, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29655746/identification-of-pyruvate-kinase-as-a-novel-allergen-in-whiteleg-shrimp-litopenaeus-vannamei-by-specific-ige-present-in-patients-with-shrimp-allergy
#14
Chih-Hung Lee, Chia-Ching Wu, Yu-Chang Tyan, Wei-Tai Yu, Edward S Huang, Hsu-Sheng Yu
Food allergy is one of the most important health issues worldwide. In Taiwan, current literature suggests shrimps and crabs are the most common causes of food allergy, and are frequently associated with acute allergic reactions such as urticaria, atopic dermatitis, and asthma. However, knowledge regarding the shrimp allergens remains limited. Thus, there is an urgent need to establish comprehensive information for elucidating underlying triggers for food allergy. In this study, whiteleg shrimp (Litopenaeus vannamei) was used to evaluate the IgE-binding properties of various shrimp proteins to 7 allergic patients' sera by western blot...
August 30, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29655584/nanoemulsion-adjuvant-driven-redirection-of-t-h-2-immunity-inhibits-allergic-reactions-in-murine-models-of-peanut-allergy
#15
Jessica J O'Konek, Jeffrey J Landers, Katarzyna W Janczak, Rishi R Goel, Anna M Mondrusov, Pamela T Wong, James R Baker
BACKGROUND: Immunotherapy for food allergies involves progressive increased exposures to food that result in desensitization to food allergens in some subjects but not tolerance to the food. Therefore new approaches to suppress allergic immunity to food are necessary. Previously, we demonstrated that intranasal immunization with a nanoemulsion (NE) adjuvant induces robust mucosal antibody and TH 17-polarized immunity, as well as systemic TH 1-biased cellular immunity with suppression of pre-existing TH 2-biased immunity...
April 11, 2018: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29650229/allergen-component-analysis-as-a-tool-in-the-diagnosis-and-management-of-occupational-allergy
#16
Monika Raulf
We are now in the epoch of "molecular allergology" and numerous clinically relevant allergenic molecules are available improving the performance of in vitro allergen tests and allergen detection methods. This review is focusing on characterized occupational allergens and their implementation into the in vitro diagnosis for occupational allergy and in allergen detection methods. More than 400 occupational agents are identified and documented as being 'respiratory sensitizers', but currently only a limited number of them are characterized on the molecular level and available for routine diagnosis as native or recombinant allergens...
April 9, 2018: Molecular Immunology
https://www.readbyqxmd.com/read/29649882/local-atopy-in-childhood-adenotonsillar-hypertrophy
#17
Kyu-Sup Cho, Seong Heon Kim, Sung-Lyong Hong, Jaeyoung Lee, Sue Jean Mun, Young Eun Roh, Young Mi Kim, Hye-Young Kim
Background Although the cause of adenotonsillar hypertrophy remains unknown, some studies have shown that allergy may be a risk factor. Purpose This study determined the levels of allergen-specific immunoglobulin E (sIgE) in the adenotonsillar tissues of children with adenotonsillar hypertrophy and evaluated the clinical significance of local atopy in adenotonsillar tissues. Methods We measured 21 types of specific immunoglobulin E in the serum and adenotonsillar tissues of 102 children with adenotonsillar hypertrophy and compared the sensitization patterns of the serum and local tissues...
January 1, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29629957/how-to-actively-treat-food-allergy
#18
Valentina Pecora, Maurizio Mennini, Veronica Calandrelli, Giampiero Patriarca, Rocco Valluzzi, Vincenzo Fierro
PURPOSE OF REVIEW: In the last years, food allergy treatment is moving away from food avoidance to interventional treatments. We review here the recent developments on immunotherapy with food allergens. RECENT FINDINGS: Oral immunotherapy remains the best studied form of food immunotherapy. In 2017, further evidence has been added to its efficacy. Its mechanisms of action are under scrutiny. To reduce its side effects, studies have been dedicated to the simultaneous use of biologics, in particular omalizumab...
April 6, 2018: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29629956/what-you-should-not-miss-from-the-systematic-reviews-and-meta-analyses-on-allergen-specific-immunotherapy-in-2017
#19
Désirée Larenas-Linnemann, Jorge A Luna-Pech
PURPOSE OF REVIEW: Allergen immunotherapy (AIT) is a well recognized and extensively studied therapeutic intervention for some allergic diseases. Every year new systematic reviews and meta-analysis provide the most powerful source of evidence to orient decision making on prevention or efficacy of AIT. We here discuss systematic reviews and meta-analyses on AIT (published January 2017 to February 2018). RECENT FINDINGS: We identified 4 systematic reviews and 10 meta-analyses...
April 6, 2018: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29629955/how-to-manage-food-dependent-exercise-induced-anaphylaxis-fdeia
#20
Tomoyuki Asaumi, Motohiro Ebisawa
PURPOSE OF REVIEW: In recent years, the number of reports on food-dependent exercise-induced anaphylaxis (FDEIA) has been increasing. This review aims to describe the standard management of FDEIA including provocation tests and identify the issues that remain unclear. RECENT FINDINGS: Provocation tests with aspirin for FDEIA enable us to confirm the definitive diagnosis and to make differential diagnosis. In some cases, FDEIA symptoms can be induced by aspirin and the causative food without exercise...
April 6, 2018: Current Opinion in Allergy and Clinical Immunology
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