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https://www.readbyqxmd.com/read/29244731/comparative-therapeutic-effects-of-plant-extract-synthesized-and-traditionally-synthesized-gold-nanoparticles-on-alcohol-induced-inflammatory-activity-in-sh-sy5y-cells-in-vitro
#1
Ashok K Singh
The present study describes potential beneficial and adverse effects of plant-extract synthesized gold nanoparticles (AuNPs) on ethanol toxicity in SH-SY5Y cells. Although kudzu root extract (K), edible-gum extract (G), alone or in combination (KG), reduced Au3+ into AuNPs, the extract's composition and the reaction temperature determined their size (AuNPKG(90<50<37) < AuNPK(90,50<37) < AuNPG(90<50); the subscript KG, K, or G is extract identification and numerical vales are reaction temperature in Celsius) and biological properties (AuNPKG(90,50>37) < AuNPK(90,50>37) < AuNPG(90,50))...
December 15, 2017: Biomedicines
https://www.readbyqxmd.com/read/29243908/thin-film-nanocomposite-membrane-with-the-minimum-amount-of-mof-by-the-langmuir-schaefer-technique-for-nanofiltration
#2
Marta Navarro, Javier Benito, Lorena Paseta, Ignacio Gascón, Joaquin Coronas, Carlos Téllez
An innovative procedure for positioning a monolayer of hydrophilic metal-organic framework (MOF) MIL-101(Cr) nanoparticles (NPs) in thin film nanocomposite (TFN) membranes has been implemented by transferring a Langmuir-Schaefer (LS) film of the MOF in between the polyamide thin layer at the top and the cross-linked asymmetric polyimide (P84®) support at the bottom. The presence and layout of the LS-MIL-101(Cr) monolayer in the TFN membrane was confirmed by STEM-HAADF images, and XPS, EDS, EELS and AFM analysis...
December 15, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29243173/magnetic-resonance-imaging-findings-of-two-cases-with-multinodular-and-vacuolating-neuronal-tumor
#3
Erkan Gökçe
Multinodular and vacuolating neuronal tumors (MVNT) are low grade neuronal tumors classified in cerebral tumors based on 2016 WHO central nerve system classification. Previously, MVNTs were probably tumors incidentally determined by imaging methods, but they could not be diagnosed or they were misdiagnosed. Two cases are reported in the present study, for which radiological imaging was carried out for epilepsy in one and for headache in the other. The first case was a twenty seven years old female patient with headache complaint...
December 14, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/29241998/the-prevalence-and-morphology-of-the-corona-mortis-crown-of-death-a-meta-analysis-with-implications-in-abdominal-wall-and-pelvic-surgery
#4
Beatrice Sanna, Brandon Michael Henry, Jens Vikse, Bendik Skinningsrud, Jakub R Pękala, Jerzy A Walocha, Roberto Cirocchi, Krzysztof A Tomaszewski
PURPOSE: Corona mortis is a highly variable vascular connection between the obturator and external iliac or inferior epigastric arteries or veins located behind the superior pubic ramus in the retropubic space (space of Retzius). Due to the significant variation in this collateral circulation, detailed anatomical knowledge of the corona mortis is vital to enhance the prevention of possible iatrogenic errors in hernia repair and other pubic surgical procedures. The aim of our meta-analysis was to provide comprehensive data on the prevalence, anatomical characteristics, and ethnic variations of the corona mortis vessel...
December 9, 2017: Injury
https://www.readbyqxmd.com/read/29239267/a-retrospective-study-of-predictors-of-return-to-duty-vs-medical-retirement-in-an-active-duty-military-population-with-blast-related-mild-traumatic-brain-injury
#5
Philip A Cook, Thomas M Johnson, Suzanne G Martin, Philip R Gerhman, Seema Bhatnagar, James C Gee
Traumatic Brain Injury (TBI), has been described as the "signature injury" of the Global War on Terror. Explosive blast TBI has become a leading cause of injury as a result of the widespread use of improvised explosive devices in Iraq and Afghanistan. We present a retrospective cross-sectional study of patients with blast-related mild TBI (N=303) seen at the Intrepid Spirit Concussion Recovery Center at Naval Medical Center Camp Lejeune. The objective was to predict outcomes of return to duty (RTD) vs. medical retirement via medical evaluation board (MEB), based on brain imaging, neuropsychological data and history of mTBI...
December 14, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29237541/life-threatening-hemorrhage-from-the-corona-mortis-treated-with-balloon-assisted-coiling-technique
#6
Xinjian Xu, Fei Teng, Jingjing Li, Juan Wu, Rui Zhu, Wenbin Ji
Isolated pubic ramus fractures are common and generally uncomplicated injuries in the elderly. However, pubic ramus fractures are closely related to important vascular structures. The corona mortis, located in the retropubis, has an important anastomotic value, as it serves as a communication between the internal and external iliac vessels. The following case report describes an 88-year-old male who was diagnosed with a right superior pubic ramus fracture, which led to a severe picture of hemodynamic instability...
December 8, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29236904/retrocochlear-impairments-in-systemic-sclerosis-a-case-report-study
#7
Julia de Souza Pinto Valente, Ana Paula Corona
PURPOSE: To report three cases of patients with Systemic Sclerosis (SSc) and retrocochlear impairments. METHODS: This is a case report of three individuals with SSc and retrocochlear impairments assisted at a rheumatology outpatient clinic. All individuals underwent Brainstem Auditory Evoked Potential (BAEP) and, when necessary, audiometry. RESULTS: All three individuals presented sensorineural hearing loss. Although no retrocochlear impairment was identified in the basic audiologic evaluation, the BAEP results were altered...
December 7, 2017: CoDAS
https://www.readbyqxmd.com/read/29235134/sex-hormone-binding-globulin-is-associated-with-androgen-deficiency-features-independently-of-total-testosterone
#8
Giulia Rastrelli, Giovanni Corona, Sarah Cipriani, Edoardo Mannucci, Mario Maggi
OBJECTIVE: It is recognized that total testosterone (TT) does not sufficiently describe androgen status when sex hormone binding globulin (SHBG) is altered. However, in humans, evidence supporting the existence of a hypogonadism due to low T bioactivity is scanty. The aim of the study was to assess whether changes in SHBG levels, independently of TT, are associated with subjective and objective androgen dependent parameters. DESIGN: Cross-sectional observation. PATIENTS: 2622 men (aged 51...
December 13, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/29232130/atom-transfer-radical-polymerization-of-multi-shelled-cationic-corona-for-the-systemic-delivery-of-sirna
#9
Hyesung Kim, Young Ju Son, Wei Mao, Kam W Leong, Hyuk Sang Yoo
We propose an effective siRNA delivery system by preparing poly(DAMA-HEMA)-multilayered gold nanoparticles using multiple surface-initiated atom transfer radical polymerization (SI-ATRP) processes. The polymeric multilayer structure is characterized by transmission electron microscopy (TEM), matrix-associated laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF), UV-Vis spectroscopy, Fourier transform infrared spectroscopy (FT-IR), dynamic light scattering (DLS) and ζ-potential. The amount of siRNA electrostatically incorporated into the nanoparticle can be tuned by the number of polymeric shells, which in turn influences the cellular uptake and gene silencing effect...
December 12, 2017: Nano Letters
https://www.readbyqxmd.com/read/29231944/stability-of-plant-virus-based-nanocarriers-in-gastrointestinal-fluids
#10
Alberto Berardi, David J Evans, Francesca Baldelli Bombelli, George P Lomonossoff
Cowpea mosaic virus (CPMV) is a plant virus which is being extensively investigated as a drug delivery and vaccine nanocarrier for parenteral administration. However, to date little is known about the suitability of plant-based nanocarriers for oral delivery. In this study, the colloidal (i.e. aggregation), physical (i.e. denaturation) and chemical (i.e. digestion of the polypeptides) stability of CPMV and its empty virus-like particles (eVLPs) in conditions resembling the gastrointestinal fluids were evaluated...
December 12, 2017: Nanoscale
https://www.readbyqxmd.com/read/29230295/modulating-protein-amyloid-aggregation-with-nanomaterials
#11
Bo Wang, Emily H Pilkington, Yunxiang Sun, Thomas P Davis, Pu Chun Ke, Feng Ding
Direct exposure or intake of nanopaticles (NPs) to the human body can invoke a series of biological responses, some of which are deleterious, and as such the role of NPs in vivo requires thorough examination. Over the past decade, it has been established that biomolecules such as proteins can bind NPs to form a 'corona', where the structures and dynamics of NP-associated proteins can assign new functionality, systemic distribution and toxicity. However, the behavior and fate of NPs in biological systems are still far from being fully understood...
September 1, 2017: Environmental Science. Nano
https://www.readbyqxmd.com/read/29228858/common-patterns-of-regional-brain-injury-detectable-by-dti-in-otherwise-normal-appearing-white-matter-in-patients-with-early-moderate-to-severe-traumatic-brain-injury
#12
Kristine O'Phelan, Chad Kuniyuki Otoshi, Thomas M Ernst, Linda Chang
Traumatic brain injury (TBI) alters the lives of millions of people every year. Although mortality rates have improved, due to better prehospital care and reduction of secondary injury in the critical care setting, improvements in functional outcomes after TBI have been difficult to achieve. Diffusion-tensor imaging (DTI) allows detailed measurement of microstructural damage in regional brain tissue after TBI, thus improving our understanding of the extent and severity of TBI. METHODS: Twenty subjects were recruited from a Neurological Intensive Care Unit, and compared to 18 healthy control subjects...
December 11, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29223324/novel-method-for-the-characterization-of-charged-polymer-self-assemblies-multidetector-thermal-field-flow-fractionation-in-aqueous-mobile-phase
#13
Guilaume Greyling, Harald Pasch
Charged block copolymer self-assemblies, such as charged micelles, have attracted much attention as versatile drug delivery systems due to their readily tunable characteristics such as size and surface charge. However, current column-based analytical techniques are not suitable to fractionate and comprehensively characterize charged micelles in terms of size, molar mass, chemical composition and morphology. Multidetector thermal field-flow fractionation (ThFFF) is shown to be a unique characterization platform that can be used to characterize charged micelles in terms of size, molar mass, chemical composition and morphology in aqueous mobile phases with various ionic strengths and pH...
December 5, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29217570/a-precise-measurement-of-the-magnetic-field-in-the-corona-of-the-black-hole-binary-v404-cygni
#14
Yigit Dallilar, Stephen S Eikenberry, Alan Garner, Richard D Stelter, Amy Gottlieb, Poshak Gandhi, Piergiorgio Casella, Vik S Dhillon, Tom R Marsh, Stuart P Littlefair, Liam Hardy, Rob Fender, Kunal Mooley, Dominic J Walton, Felix Fuerst, Matteo Bachetti, A J Castro-Tirado, Miguel Charcos, Michelle L Edwards, Nestor M Lasso-Cabrera, Antonio Marin-Franch, S Nicholas Raines, Kendall Ackley, John G Bennett, A Javier Cenarro, Brian Chinn, H Veronica Donoso, Raymond Frommeyer, Kevin Hanna, Michael D Herlevich, Jeff Julian, Paola Miller, Scott Mullin, Charles H Murphey, Chris Packham, Frank Varosi, Claudia Vega, Craig Warner, A N Ramaprakash, Mahesh Burse, Sujit Punnadi, Pravin Chordia, Andreas Gerarts, Héctor de Paz Martín, María Martín Calero, Riccardo Scarpa, Sergio Fernandez Acosta, William Miguel Hernández Sánchez, Benjamin Siegel, Francisco Francisco Pérez, Himar D Viera Martín, José A Rodríguez Losada, Agustín Nuñez, Álvaro Tejero, Carlos E Martín González, César Cabrera Rodríguez, Jordi Molgó, J Esteban Rodriguez, J Israel Fernández Cáceres, Luis A Rodríguez García, Manuel Huertas Lopez, Raul Dominguez, Tim Gaggstatter, Antonio Cabrera Lavers, Stefan Geier, Peter Pessev, Ata Sarajedini
Observations of binary stars containing an accreting black hole or neutron star often show x-ray emission extending to high energies (>10 kilo--electron volts), which is ascribed to an accretion disk corona of energetic particles akin to those seen in the solar corona. Despite their ubiquity, the physical conditions in accretion disk coronae remain poorly constrained. Using simultaneous infrared, optical, x-ray, and radio observations of the Galactic black hole system V404 Cygni, showing a rapid synchrotron cooling event in its 2015 outburst, we present a precise 461 ± 12 gauss magnetic field measurement in the corona...
December 8, 2017: Science
https://www.readbyqxmd.com/read/29216541/texting-while-walking-differently-alters-gait-patterns-in-people-with-multiple-sclerosis-and-healthy-individuals
#15
Massimiliano Pau, Federica Corona, Giuseppina Pilloni, Micaela Porta, Giancarlo Coghe, Eleonora Cocco
BACKGROUND: In recent times, increasing safety concerns have been associated with the use of mobile phones by pedestrians. In particular, texting has been shown to significantly alter gait patterns. However, no specific investigations have been performed on people with Multiple Sclerosis (pwMS), who are already characterized by gait dysfunctions caused by the disease. OBJECTIVE: To assess the existence of possible alterations in spatio-temporal parameters of gait in pwMS when simultaneously texting on a smartphone and walking...
December 2, 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29215914/feasibility-and-effectiveness-of-a-parenting-programme-for-mexican-parents-of-children-with-acquired-brain-injury-case-report
#16
Clara Chavez-Arana, Cathy Catroppa, Guillermina Yáñez Téllez, Celia Godfrey, Belén Prieto-Corona, Miguel A de León, Antonio García, Vicki Anderson
BACKGROUND: Acquired brain injury (ABI) during childhood typically causes behaviour problems in the child and high levels of stress in the family. OBJECTIVES: (1) To investigate the feasibility and effectiveness of a parenting programme to: improve behaviour and self-regulation (SR) in Mexican children with ABI, enhance parenting skills, and decrease parental stress in parents of children with ABI; (2) to explore the impact of parent SR on child. METHODS: Case study design with four participants post-ABI, aged 7-12 years, recruited in Mexico City...
December 7, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29213254/blue-light-therapy-following-mild-traumatic-brain-injury-effects-on-white-matter-water-diffusion-in-the-brain
#17
Sahil Bajaj, John R Vanuk, Ryan Smith, Natalie S Dailey, William D S Killgore
Mild traumatic brain injury (mTBI) is a common and often inconspicuous wound that is frequently associated with chronic low-grade symptoms and cognitive dysfunction. Previous evidence suggests that daily blue wavelength light therapy may be effective at reducing fatigue and improving sleep in patients recovering from mTBI. However, the effects of light therapy on recovering brain structure remain unexplored. In this study, we analyzed white matter diffusion properties, including generalized fractional anisotropy, and the quantity of water diffusion in isotropic (i...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29206030/a-decade-of-the-protein-corona
#18
Pu Chun Ke, Sijie Lin, Wolfgang J Parak, Thomas P Davis, Frank Caruso
In this Perspective, we reflect on a decade of research on the protein corona and contemplate its broad implications for future science and engineering at the bio-nano interface. Specifically, we focus on the physical origins and time evolution of the protein corona, differences in the nanoparticle-protein entity in in vitro and in vivo environments, the role of stealth polymers to minimize the formation of the protein corona, relevant computational and theoretical developments, and the "biocorona", a concept extrapolated from the field of nanomedicine...
December 5, 2017: ACS Nano
https://www.readbyqxmd.com/read/29204342/sex-differences-in-white-matter-alterations-following-repetitive-subconcussive-head-impacts-in-collegiate-ice-hockey-players
#19
Nico Sollmann, Paul S Echlin, Vivian Schultz, Petra V Viher, Amanda E Lyall, Yorghos Tripodis, David Kaufmann, Elisabeth Hartl, Philipp Kinzel, Lorie A Forwell, Andrew M Johnson, Elaine N Skopelja, Christian Lepage, Sylvain Bouix, Ofer Pasternak, Alexander P Lin, Martha E Shenton, Inga K Koerte
Objective: Repetitive subconcussive head impacts (RSHI) may lead to structural, functional, and metabolic alterations of the brain. While differences between males and females have already been suggested following a concussion, whether there are sex differences following exposure to RSHI remains unknown. The aim of this study was to identify and to characterize sex differences following exposure to RSHI. Methods: Twenty-five collegiate ice hockey players (14 males and 11 females, 20...
2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/29204123/network-modularity-in-breast-cancer-molecular-subtypes
#20
Sergio Antonio Alcalá-Corona, Guillermo de Anda-Jáuregui, Jesús Espinal-Enríquez, Enrique Hernández-Lemus
Breast cancer is a heterogeneous and complex disease, a clear manifestation of this is its classification into different molecular subtypes. On the other hand, gene transcriptional networks may exhibit different modular structures that can be related to known biological processes. Thus, modular structures in transcriptional networks may be seen as manifestations of regulatory structures that tightly controls biological processes. In this work, we identify modular structures on gene transcriptional networks previously inferred from microarray data of molecular subtypes of breast cancer: luminal A, luminal B, basal, and HER2-enriched...
2017: Frontiers in Physiology
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