keyword
MENU ▼
Read by QxMD icon Read
search

Corona

keyword
https://www.readbyqxmd.com/read/28731222/bio-nano-interface-and-environment-a-critical-review
#1
Gerardo Pulido-Reyes, Francisco Leganes, Francisca Fernández-Piñas, Roberto Rosal
The Bio-Nano interface is the boundary where the Engineered NanoMaterials (ENM) meet the biological system, exerting the biological function for what they have been designed or inducing adverse effects to other cells or organisms when they reach non-target scenarios, i.e: the natural environment. Research has been performed to determine the fate, transport, and toxic properties of ENM, but much of it focused on pristine or "as manufactured" ENM or where modifications of the materials were not assessed. This article reviews the most recent progresses regarding the Bio-Nano interface and the transformations that ENM suffer in the environment, paying special attention to the adsorption of environmental biomolecules on the surface of ENM...
July 21, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28729533/common-brain-structure-findings-across-children-with-varied-reading-disability-profiles
#2
Mark A Eckert, Kenneth I Vaden, Amanda B Maxwell, Stephanie L Cute, Mulugeta Gebregziabher, Virginia W Berninger
Dyslexia is a developmental disorder in reading that exhibits varied patterns of expression across children. Here we examined the degree to which different kinds of reading disabilities (defined as profiles or patterns of reading problems) contribute to brain morphology results in Jacobian determinant images that represent local brain shape and volume. A matched-pair brain morphometry approach was used to control for confounding from brain size and research site effects in this retrospective multi-site study of 134 children from eight different research sites...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28724595/hypertensive-encephalopathy-mimicking-cerebral-vasculitis-with-pontine-oedema-cerebellar-white-matter-lesions-and-multiple-cerebral-infarctions
#3
Daniela Ceccarelli, David Hargroves, Ibrahim Balogun, Thomas Webb
A 47-year-old man with poorly controlled hypertension presented with headaches, right-sided weakness and dysarthria. CT and MRI scans of the brain showed widespread abnormalities including significant pontine oedema, basal ganglia and corona radiata infarctions and cerebellar white matter high signal. Imaging of the intracerebral vasculature also demonstrated wall irregularities. Initially a central nervous system inflammatory disorder was thought to be the most likely diagnosis, possibly acute demyelinating encephalomyelitis or cerebral vasculitis, and the patient was treated with high-dose intravenous steroids...
July 19, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28724292/adsorption-of-proteins-on-colloidal-lignin-particles-for-advanced-biomaterials
#4
Timo Leskinen, Joanna Witos, Juan José Valle Delgado, Kalle Sakari Lintinen, Mauri A Kostiainen, Susanne Kristina Wiedmer, Monika Österberg, Maija-Liisa Mattinen
Coating of colloidal lignin particles (CLPs), or lignin nanoparticles (LNPs), with proteins was evaluated in order to establish a safe, self-assembly-mediated modification technique to tune their surface chemistry. Gelatin and poly- L-lysine formed the most pronounced protein corona on the CLP surface, as determined by dynamic light scattering (DLS) and zeta potential measurements. Spherical morphology of individual protein coated CLPs was confirmed by transmission electron (TEM) and atomic force (AFM) microscopy...
July 19, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28723467/human-papillomavirus-infection-and-vaccination-in-males
#5
REVIEW
Eugenio Ventimiglia, Simon Horenblas, Asif Muneer, Andrea Salonia
CONTEXT: Human papillomavirus (HPV) is the commonest sexually transmitted pathogen in humans and is linked to the aetiopathogenesis for both benign and malignant disease in men. OBJECTIVE: To evaluate and summarise the evidence for HPV infection and vaccination in men. EVIDENCE ACQUISITION: A search of Medline, PubMed, and Scopus was performed to identify articles published in English within the last 10 yr addressing HPV epidemiology, the natural history of HPV infection and its long-term consequences, and vaccination in men...
October 2016: European Urology Focus
https://www.readbyqxmd.com/read/28719260/symptomatic-falciparum-malaria-after-living-in-a-nonendemic-area-for-10-years-recrudescence-or-indigenous-transmission
#6
Joaquín Salas-Coronas, Manuel Jesús Soriano-Pérez, Ana B Lozano-Serrano, Rosario Pérez-Moyano, Carmen Porrino-Herrera, María Teresa Cabezas-Fernández
AbstractWe report the case of a patient from Mali who, after 10 years of living in Spain, presented with symptomatic Plasmodium falciparum malaria without having visited an endemic area during that time. We cannot completely rule out the possibility of indigenous transmission, but this case most likely represents recrudescence of an infection acquired over 10 years earlier.
June 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28718977/effect-of-simulated-gastrointestinal-digestion-and-fermentation-on-polyphenolic-content-and-bioactivity-of-brown-seaweed-phlorotannin-rich-extracts
#7
Giulia Corona, Maria Magdalena Coman, Yuxuan Guo, Sarah Hotchkiss, Chris Gill, Parveen Yaqoob, Jeremy P E Spencer, Ian Rowland
SCOPE: Unlike other classes of polyphenols, there is a lack of knowledge regarding brown seaweed phlorotannins and their bioactivity. We investigated the impact of in vitro gastrointestinal digestion and colonic fermentation on the bioactivity of a seaweed phlorotannin extract from Ascophyllum nodosum and its high molecular weight (HMW) and low molecular weight (LMW) fractions. METHODS AND RESULTS: The highest phlorotannin and total polyphenol (TP) concentration was observed in the HMW fraction...
July 18, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28715860/hemoglobin-bioconjugates-with-surface-protected-gold-nanoparticles-in-aqueous-media-the-stability-depends-on-solution-ph-and-protein-properties
#8
Rafael Del Caño, Lucia Mateus, Guadalupe Sánchez-Obrero, José Manuel Sevilla, Rafael Madueño, Manuel Blázquez, Teresa Pineda
The identification of the factors that dictate the formation and physicochemical properties of protein-nanomaterial bioconjugates are important to understand their behavior in biological systems. The present work deals with the formation and characterization of bioconjugates made of the protein hemoglobin (Hb) and gold nanoparticles (AuNP) capped with three different molecular layers (citrate anions (c), 6-mercaptopurine (MP) and ω-mercaptoundecanoic acid (MUA)). The main focus is on the behavior of the bioconjugates in aqueous buffered solutions in a wide pH range...
July 5, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28712204/middle-east-respiratory-syndrome-corona-virus-alert-verification-in-mirpur-azad-kashmir
#9
Mumtaz Ali Khan, Muhammad Ishaq, Mujeeb Ur Rehman, Asim Altaf, Mirza Aamir Baig, Safdar Rana, Jaleel Kamran, Muazam Abbas Ranjha, Jawad Asgher Rana
BACKGROUND: Middle East Respiratory-Corona virus (MERS-CoV), SARS like virus, identified in September 2012 in Middle-East. February 2013, an elderly man, who visited Pakistan and KSA, was confirmed as MRS-CoV in UK. A team visited Mirpur to assess current and past SARI trends in major indoor facilities, to explore possible contact of the patient with known or suspected SARI case during his stay in Pakistan and enlist close contacts. METHODS: Review of indoor records in hospitals, interviews with relatives & physicians and active contact tracing using operational case definition...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28712035/ginsenoside-improves-physicochemical-properties-and-bioavailability-of-curcumin-loaded-nanostructured-lipid-carrier
#10
Ajay Vijayakumar, Rengarajan Baskaran, Han-Joo Maeng, Bong Kyu Yoo
The aim of this study was to develop a ginsenoside-modified nanostructured lipid carrier (G-NLC) dispersion containing curcumin. The NLC was prepared by melt emulsification with slight modification process. Different G-NLC dispersion systems were prepared using lipid carrier matrix composed of ginsenoside, phosphatidylcholine, lysophosphatidylcholine, and hydrogenated bean oil. TEM image of the nanoparticles in the NLC dispersion showed core/shell structure, and there was corona-like layer surrounding the particles in the G-NLC...
July 15, 2017: Archives of Pharmacal Research
https://www.readbyqxmd.com/read/28710547/cross-cultural-adaptation-and-validation-of-the-italian-version-of-the-kerlan-jobe-orthopaedic-clinic-shoulder-and-elbow-score
#11
Giovanni Merolla, Katia Corona, Gustavo Zanoli, Simone Cerciello, Stefano Giannotti, Giuseppe Porcellini
BACKGROUND: The Kerlan-Jobe Orthopaedic Clinic (KJOC) Shoulder and Elbow score is a reliable and sensitive tool to measure the performance of overhead athletes. The purpose of this study was to carry out a cross-cultural adaptation and validation of the KJOC questionnaire in Italian and to assess its reliability, validity, and responsiveness. MATERIALS AND METHODS: Ninety professional athletes with a painful shoulder were included in this study and were assigned to the "injury group" (n = 32) or the "overuse group" (n = 58); 65 were managed conservatively and 25 were treated by arthroscopic surgery...
July 14, 2017: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/28709718/gadoxetic-acid-enhanced-high-temporal-resolution-hepatic-arterial-phase-imaging-with-view-sharing-technique-impact-on-the-li-rads-category
#12
Satoshi Goshima, Yoshifumi Noda, Kimihiro Kajita, Nobuyuki Kawai, Hiromi Koyasu, Hiroshi Kawada, Masayuki Matsuo, Kyongtae T Bae
PURPOSE: To evaluate the value of view-sharing multi-hepatic arterial-phase (mHAP) imaging for diagnosis of hypervascular hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Forty-seven consecutive patients with HCC underwent gadoxetic acid-enhanced magnetic resonance (MR) imaging before angiographic and lipiodol CT. Hepatic arterial-phase images were obtained at 5 consecutive phases with shared central k-space of 25%, followed by portal venous, late (2 and 3min), and hepatobiliary phase imaging...
July 3, 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28705622/long-term-toxicological-effects-of-persistent-luminescence-nanoparticles-after-intravenous-injection-in-mice
#13
Gonzálo Ramírez-García, Silvia Gutiérrez-Granados, Marco A Gallegos-Corona, Lourdes Palma-Tirado, Fanny d'Orlyé, Anne Varenne, Nathalie Mignet, Cyrille Richard, Minerva Martínez-Alfaro
The ZnGa1.995Cr0.005O4 persistent luminescence nanoparticles offer the promise of revolutionary tools for biological imaging with applications such as cell tracking or tumor detection. They can be re-excited through living tissues by visible photons, allowing observations without any time constraints and avoiding the undesirable auto-fluorescence signals observed when fluorescent probes are used. Despite all these advantages, their uses demand extensive toxicological evaluation and control. With this purpose, mice were injected with a single intravenous administration of hydroxylated or PEGylated persistent luminescence nanoparticles at different concentrations and then a set of standard tests were carried out 1day, 1 month and 6 months after the administration...
July 10, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28704605/protein-adsorption-to-charged-gold-nanospheres-as-a-function-of-protein-deformability
#14
Jordan M Dennison, Jennifer M Zupancic, Wayne Lin, Jonathan H Dwyer, Catherine J Murphy
The corona that forms as protein adsorbs to gold nanospheres (AuNSs) is directly influenced by the surface chemistry of the AuNS. Tools to predict adsorption outcomes are needed for intelligent design of nanomaterials for biological applications. We hypothesized that the denaturation behavior of a protein might be a useful predictor of adsorption behavior to AuNSs, and used this idea to study protein adsorption to anionic citrate capped AuNSs and to cationic poly(allylamine hydrochloride) (PAH) wrapped AuNSs...
July 13, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28703921/estimating-and-modelling-the-transmissibility-of-middle-east-respiratory-syndrome-corona-virus-during-the-2015-outbreak-in-the-republic-of-korea
#15
Xu-Sheng Zhang, Richard Pebody, Andre Charlett, Daniela de Angelis, Paul Birrell, Hunseok Kang, Marc Baguelin, Yoon Hong Choi
BACKGROUND: Emerging respiratory infections represent a significant public health threat. Because of their novelty, there are limited measures available to control their early spread. Learning from past outbreaks is important for future preparation. The MERS-CoV 2015 outbreak in the Republic of Korea (ROK) provides one such opportunity. OBJECTIVES: We demonstrated through quantitative methodologies how to estimate MERS-CoV's transmissibility and identified the effective countermeasures that stopped its spread...
July 13, 2017: Influenza and Other Respiratory Viruses
https://www.readbyqxmd.com/read/28702661/clinically-approved-pegylated-nanoparticles-are-covered-by-a-protein-corona-that-boosts-the-uptake-by-cancer-cells
#16
M Papi, D Caputo, V Palmieri, R Coppola, S Palchetti, F Bugli, C Martini, L Digiacomo, D Pozzi, G Caracciolo
Today, liposomes are an advanced technology of drug carriers with a dozen drugs in clinical practice and many more in clinical trials. A bottleneck associated with the clinical translation of liposomes has long been 'opsonization', i.e. the adsorption of plasma proteins at the liposome surface resulting in their rapid clearance from circulation. For decades, the most popular way to avoid opsonization has been grafting polyethylene glycol (PEG) onto the liposome surface. Recent studies have clarified that grafting PEG onto the liposome surface reduces, but does not completely prevent protein binding...
July 12, 2017: Nanoscale
https://www.readbyqxmd.com/read/28702354/white-matter-integrity-in-dyskinetic-cerebral-palsy-relationship-with-intelligence-quotient-and-executive-function
#17
Olga Laporta-Hoyos, Kerstin Pannek, Júlia Ballester-Plané, Lee B Reid, Élida Vázquez, Ignacio Delgado, Leire Zubiaurre-Elorza, Alfons Macaya, Pilar Póo, Mar Meléndez-Plumed, Carme Junqué, Roslyn Boyd, Roser Pueyo
BACKGROUND: Dyskinetic cerebral palsy (CP) is one of the most disabling motor types of CP and has been classically associated with injury to the basal ganglia and thalamus. Although cognitive dysfunction is common in CP, there is a paucity of published quantitative analyses investigating the relationship between white matter (WM) microstructure and cognition in this CP type. AIMS: This study aims (1) to compare brain WM microstructure between people with dyskinetic CP and healthy controls, (2) to identify brain regions where WM microstructure is related to intelligence and (3) to identify brain regions where WM microstructure is related to executive function in people with dyskinetic CP and (4) to identify brain regions where the correlations are different between controls and people with CP in IQ and executive functions...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28695931/methods-of-protein-corona-isolation-for-magnetic-nanoparticles
#18
Debora Bonvin, Diego Chiappe, Marc Moniatte, Heinrich Hofmann, Marijana Mionić Ebersold
Nanoparticles (NPs) in contact with a biological environment get covered by proteins and some are loosely bound and some are tightly bound. The latter form a hard protein corona (HPC) which is known to determine their biological behavior. Therefore, in order to study the biological behaviour of NPs one needs to start from the HPC. However, established methods and standards of HPC isolation are still not known. This is especially a challenge in the case of magnetic NPs which form a major branch of nanomedicine...
July 11, 2017: Analyst
https://www.readbyqxmd.com/read/28694329/feminization-of-male-mouse-liver-by-persistent-growth-hormone-stimulation-activation-of-sex-biased-transcriptional-networks-and-dynamic-changes-in-chromatin-states
#19
Dana Lau-Corona, Alexander Suvorov, David J Waxman
Sex-dependent pituitary GH secretory profiles--pulsatile in males and persistent in females--regulate sex-biased, STAT5-dependent expression of hundreds of genes in mouse liver, imparting sex differences in hepatic drug/lipid metabolism and disease risk. Here we examine transcriptional and epigenetic changes induced by continuous-GH infusion (cGH) in male mice, which rapidly feminizes the temporal profile of liver STAT5 activity. cGH repressed 86% of male-biased genes and induced 68% of female-biased genes within 4-days; however, several highly female-specific genes showed weak or no feminization, even after 14-days cGH...
July 10, 2017: Molecular and Cellular Biology
https://www.readbyqxmd.com/read/28691585/hyper-brain-connectivity-in-binge-drinking-college-students-a-diffusion-tensor-imaging-study
#20
Karl Kashfi, Kareem Al-Khalil, Jiancheng Hou, Dan Fang, Ron Anderson, Ravi Rajmohan, Peter Syapin, Michael W O'Boyle
The current study used diffusion tensor imaging to examine patterns/degree of brain connectivity in 12 college-aged binge drinking (BD) and 12 moderate drinking individuals. Voxel-level and region-of-interest analyses revealed increased connectivity of the BD brain in the right corona radiata, right external capsule, and both the right and left cingulum. Also, fractional anisotropy and axial diffusivity values of these regions correlated with a number of drinking behaviors of the BD as well as both groups combined...
July 10, 2017: Neurocase
keyword
keyword
3395
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"