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https://www.readbyqxmd.com/read/28212153/new-therapies-for-the-prevention-and-treatment-of-exacerbations-of-bronchiectasis
#1
Hani Abo-Leyah, James D Chalmers
PURPOSE OF REVIEW: Exacerbations of bronchiectasis have a major impact on quality of life, healthcare costs, and long-term risk of complications. Preventing exacerbations is one of the major goals of treatment. Bronchiectasis is increasingly recognized and the impact of bronchiectasis exacerbations on daily clinical practice is also increasing. RECENT FINDINGS: Preventing bronchiectasis exacerbations are dependent on appropriate risk assessment, identifying the patients at highest risk to rationally target preventive therapies...
February 16, 2017: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/28210864/pharmacy-benefit-management-companies-do-they-create-value-in-the-us-healthcare-system
#2
Alan Lyles
Pharmacy benefit management companies (PBMs) perform functions in the US market-based healthcare system that may be performed by public agencies or quasi-public institutions in other nations. By aggregating lives covered under their many individual contracts with payers, PBMs have formidable negotiating power. They influence pharmaceutical insurance coverage, design the terms of coverage in a plan's drug benefit, and create competition among providers for inclusion in a plan's network. PBMs have, through intermediation, the potential to secure lower drug prices and to improve rational prescribing...
February 16, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28192746/changing-the-navigator-s-course-how-the-increasing-rationalization-of-healthcare-influences-access-for-undocumented-immigrants-under-the-affordable-care-act
#3
Laura López-Sanders
A number of researchers have shown that brokers (e.g., navigators and street-level bureaucrats) bridge access to healthcare services and information for immigrant patients through rich personal relationships and a mission of ethical care. An open question remains concerning how the increasing rationalization of healthcare over the past few decades influences brokerage for undocumented immigrant patients. Drawing from fieldwork and interviews conducted in California, as the Affordable Care Act (ACA) was implemented, I develop the concept of the "double-embedded-liaison...
February 2, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28191922/synergistic-integration-of-experimental-and-simulation-approaches-for-the-de-novo-design-of-silk-based-materials
#4
Wenwen Huang, Davoud Ebrahimi, Nina Dinjaski, Anna Tarakanova, Markus J Buehler, Joyce Y Wong, David L Kaplan
Tailored biomaterials with tunable functional properties are crucial for a variety of task-specific applications ranging from healthcare to sustainable, novel bio-nanodevices. To generate polymeric materials with predictive functional outcomes, exploiting designs from nature while morphing them toward non-natural systems offers an important strategy. Silks are Nature's building blocks and are produced by arthropods for a variety of uses that are essential for their survival. Due to the genetic control of encoded protein sequence, mechanical properties, biocompatibility, and biodegradability, silk proteins have been selected as prototype models to emulate for the tunable designs of biomaterial systems...
February 13, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28187802/critical-care-management-of-traumatic-brain-injury
#5
D K Menon, A Ercole
Traumatic brain injury (TBI) is a growing global problem, which is responsible for a substantial burden of disability and death, and which generates substantial healthcare costs. High-quality intensive care can save lives and improve the quality of outcome. TBI is extremely heterogeneous in terms of clinical presentation, pathophysiology, and outcome. Current approaches to the critical care management of TBI are not underpinned by high-quality evidence, and many of the current therapies in use have not shown benefit in randomized control trials...
2017: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/28173764/-medically-unexplained-symptoms-and-symptom-disorders-in-primary-care-prognosis-based-recognition-and-classification
#6
EDITORIAL
Marianne Rosendal, Tim C Olde Hartman, Aase Aamland, Henriette van der Horst, Peter Lucassen, Anna Budtz-Lilly, Christopher Burton
BACKGROUND: Many patients consult their GP because they experience bodily symptoms. In a substantial proportion of cases, the clinical picture does not meet the existing diagnostic criteria for diseases or disorders. This may be because symptoms are recent and evolving or because symptoms are persistent but, either by their character or the negative results of clinical investigation cannot be attributed to disease: so-called "medically unexplained symptoms" (MUS). MUS are inconsistently recognised, diagnosed and managed in primary care...
February 7, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28148332/what-s-new-in-graduate-medical-education
#7
Raquel G Hernandez
The development of new graduate medical education programmes provides both opportunities and challenges. Efforts to address physician workforce shortages as well as a realisation that curricula need to be updated to adjust to our rapidly changing healthcare environment have resulted in more educators considering the "how to" and "what's new" of programme development. Understanding the Next Accreditation System, an accreditation system introduced by the Accreditation Council of Graduate Medical Education in 2012, is critical to the success of new as well as existing residency and fellowship programmes...
December 2016: Cardiology in the Young
https://www.readbyqxmd.com/read/28139971/evaluation-of-drug-prescribing-patterns-based-on-the-who-prescribing-indicators-at-outpatient-clinics-of-five-hospitals-in-jordan-a%C3%A2-cross-sectional-study%C3%A2
#8
Ahmad Al-Azayzih, Sayer I Al-Azzam, Karem H Alzoubi, Mohammad Shawaqfeh, Majed M Masadeh
BACKGROUND: Irrational drug prescribing is considered one of the major challenges for the healthcare sectors worldwide, leading to negative outcomes in patients including various drug-related problems, such as polypharmacy, adverse drug events, more demands on drug monitoring, and unwanted increase in treatment cost. OBJECTIVE: The main objective of this study was to evaluate the trends and issues related to prescription at outpatient hospital pharmacies in Jordan and to contrast that to the WHO rational medication list and WHO drug use indicators...
January 30, 2017: International Journal of Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28134678/what-is-new-in-the-management-of-skin-and-soft-tissue-infections-in-2016
#9
Garyphallia Poulakou, Efthymia Giannitsioti, Sotirios Tsiodras
PURPOSE OF REVIEW: Skin and soft tissue infections (SSTIs) are the most frequent infectious cause of referrals to emergency departments and hospital admissions in developed world, contributing to significant morbidity and healthcare expenditures. We sought to review recent literature covering epidemiology and management of SSTIs. RECENT FINDINGS: Incidence trends of SSTIs were increasing worldwide with Staphylococcus aureus and streptococci predominating and methicillin-resistant S...
January 27, 2017: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/28127654/-postoperative-wound-infections-diagnosis-classification-and-treatment
#10
D Seidel, J Bunse
BACKGROUND: Surgical site infections are a frequent complication of surgery and a severe burden for the patient as well as for the healthcare system. Sound knowledge of the disease pattern is an essential prerequisite for effective therapy. OBJECTIVE: This article presents an overview of the diagnosis, classification and treatment options for surgical site infections. MATERIAL AND METHODS: Based on the existing experience, the currently available evidence and pathophysiological considerations, an overview of the diagnostic possibilities, the existing classification systems and the treatment options is presented...
January 26, 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/28094587/applying-theories-to-better-understand-socio-political-challenges-in-implementing-evidence-based-work-disability-prevention-strategies
#11
Christian Ståhl, Katia Costa-Black, Patrick Loisel
PURPOSE: This article explores and applies theories for analyzing socio-political aspects of implementation of work disability prevention (WDP) strategies. METHOD: For the analysis, theories from political science are explained and discussed in relation to case examples from three jurisdictions (Sweden, Brazil and Québec). RESULTS: Implementation of WDP strategies may be studied through a conceptual framework that targets: (1) the institutional system in which policy-makers and other stakeholders reside; (2) the ambiguity and conflicts regarding what to do and how to do it; (3) the bounded rationality, path dependency and social systems of different stakeholders; and (4) coalitions formed by different stakeholders and power relations between them...
January 17, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28089281/features-of-public-healthcare-services-provided-to-migrant-patients-in-the-eastern-macedonia-and-thrace-region-greece
#12
Christos A Tsitsakis, Anastasios Karasavvoglou, Efstathios Tsaridis, Georgia Ramantani, Giannoula Florou, Persefoni Polychronidou, Stamatios Stamatakis
BACKGROUND: The influx of migrants, refugees and asylum-seekers into European Union (EU) countries, especially into Greece, in the last 20 years is an issue of growing concern and requires a rational approach. The aim of this study is to chart the use of public health services by the migrants of the Eastern Macedonia and Thrace Region, which forms the northeastern border of Greece. METHODS: We collected data from five of the six public hospitals in the specified region, and we carried out a per clinic cross tabulation analysis of admission diagnosis and citizenship variables in order to establish the frequency at which the various diagnoses emerge per distinct group of migrant and non-migrant patients in each clinic...
December 27, 2016: Health Policy
https://www.readbyqxmd.com/read/28073721/the-contribution-of-the-french-muskoka-fund-to-improving-access-to-essential-medicines-and-priority-health-products-for-mothers-and-children
#13
C Macé, J-B Nikiema
One objective of the French Muskoka Fund since 2011 has been to improve the availability of quality healthcare services for mothers and children and thus to contribute to the continued presence of essential drugs and affordable quality health products and to their rational use by healthcare personnel. This project thus contributed to reinforcing the work of the national regulatory authorities, guarantor of the quality of the products supplied to the populations, but also to strengthening the coordination of supplies at the country level...
November 1, 2016: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/28057183/immunoth%C3%A3-rapie-une-innovation-de-rupture-non-soutenable-%C3%A3-conomiquement
#14
Jean-Pierre Thierry
A NON-SUSTAINABLE BREAKTHROUGH?: The arrival of new immunotherapy anticancer drugs on the market marks a turning point. Their reference prices are fixed in the US and are positioned at the same level that the anticancer targeted therapies. They benefit from an accelerated approval process and often obtain the status of orphan drugs. The extensions of indications to many cancers and the likely combinations could significantly increase healthcare spending at a level that recently unveiled their non-sustainability, due to unrealistic prices approved by regulators...
November 2016: Bulletin du Cancer
https://www.readbyqxmd.com/read/27992278/definition-of-compassion-in-healthcare-a-systematic-literature-review
#15
REVIEW
Encarnación Perez-Bret, Rogelio Altisent, Javier Rocafort
AIM: To reflect on the definition of compassion and analyse the concepts encompassed by the term. BACKGROUND: A large number of authors have defined compassion, with certain nuances that differ from case to case. This raises the need for specificity in the definition of the term. DATA SOURCES: First, a systematic search was conducted of scientific databases. Second, a selection of experts were consulted and a request made to them for specific articles...
December 2016: International Journal of Palliative Nursing
https://www.readbyqxmd.com/read/27987098/a-surgical-department-for-intensified-care
#16
Pierluigi di Sebastiano, Tommaso Grottola, Anna Maysse, Maria Marino, Francesco Zavattaro, Pas Quale Flacco, F Francesco di Mola
PURPOSE: The growing pressure to rationalize costs in the healthcare system demands the development of new healthcare models aimed at allowing patients to receive the best treatment, without ignoring the rising costs. METHODS: In the Healthcare Unit 2 located in the Abruzzo region in Italy, a new model of intensified care surgical department was designed in January 2013. The department was based on the selection of the degree of patient disease. Patients requiring a medium-low degree surgery were treated in the peripheral unit, in the Ortona hospital, while more complex surgical procedures, most cancer cases (including stomach, liver, pancreas, colon-rectum or multi-organ resections), were performed in the central unit in the Chieti hospital...
December 16, 2016: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/27974913/product-policy-the-main-component-of-the-marketing-mix-in-the-romanian-health-services
#17
EDITORIAL
B I Coculescu, V L Purcarea, E C Coculescu
The objectives of the reforms in the EU healthcare systems are based on the implementation of the marketing concept in the health systems, which are, among other things: • efficient management of the financial resources and control costs of the rendered health services; • increased satisfaction of the clients of health care services; • broad accessibility to health services; • effective implementation of modern technologies; • rational stimulation of medical services consumption; • achievement of a fair and neutral competition between the public/ private providers and health insurance companies; • introduction of performance criteria in order to increase the incomes of the medical staff and hierarchy in hospitals; • implementation of modern management methods in health services management; • decentralization of the public healthcare system...
January 2016: Journal of Medicine and Life
https://www.readbyqxmd.com/read/27931213/assessment-of-core-drug-use-indicators-using-who-inrud-methodology-at-primary-healthcare-centers-in-bahawalpur-pakistan
#18
Muhammad Atif, Muhammad Rehan Sarwar, Muhammad Azeem, Mubeen Naz, Salma Amir, Kashaf Nazir
BACKGROUND: Proper utilization of medicines is a critical component of pharmaceutical care plan. The aim of this study was to assess drug use pattern at ten primary healthcare centers (PHCCs) of the Bahawalpur district of the Punjab province of Pakistan by employing the WHO/INRUD core drug use indicators. METHODS: This was a descriptive, non-experimental and cross-sectional study. For the prescribing indicators, 1000 prescriptions (100 prescriptions per PHCC) were systematically sampled out of the total 290,000 prescriptions written during January to December 2014...
December 8, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27925047/a-pioneering-healthcare-model-applying-large-scale-production-concepts-principles-and-performance-after-more-than-11-000-transplants-at-hospital-do-rim
#19
José Medina Pestana
The kidney transplant program at Hospital do Rim (hrim) is a unique healthcare model that applies the same principles of repetition of processes used in industrial production. This model, devised by Frederick Taylor, is founded on principles of scientific management that involve planning, rational execution of work, and distribution of responsibilities. The expected result is increased efficiency, improvement of results and optimization of resources. This model, almost completely subsidized by the Unified Health System (SUS, in the Portuguese acronym), has been used at the hrim in more than 11,000 transplants over the last 18 years...
October 2016: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/27892723/optimization-and-stratification-of-multiple-sclerosis-treatment-in-fast-developing-economic-countries-a-perspective-from-qatar
#20
Dirk Deleu, Boulenouar Mesraoua, Hisham El Khider, Beatriz Canibano, Gayane Melikyan, Hassan Al Hail, Noha Mhjob, Anjushri Bhagat, Faiza Ibrahim, Yolande Hanssens
OBJECTIVE: The introduction of disease-modifying therapies (DMTs) - with varying degrees of efficacy for reducing annual relapse rate and disability progression - has considerably transformed the therapeutic landscape of relapsing-remitting multiple sclerosis (RRMS). We aim to develop rational evidence-based treatment recommendations and algorithms for the management of clinically isolated syndrome (CIS) and RRMS that conform to the healthcare system in a fast-developing economic country such as Qatar...
December 31, 2016: Current Medical Research and Opinion
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