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https://www.readbyqxmd.com/read/27914857/imidacloprid-induces-various-toxicological-effects-related-to-the-expression-of-3%C3%AE-hsd-nr5a1-and-ogg1-genes-in-mature-and-immature-rats
#1
Amany Abdel-Rahman Mohamed, Wafaa A M Mohamed, Safaa I Khater
This study aimed to evaluate the adverse effects of the insecticide imidacloprid (IMI) on male spermatogenesis, steroidogenesis, and DNA damage in sexually mature and immature rats. Forty male rats (mature and immature) were equally divided into four groups: two mature and two immature groups. IMI groups of both ages were orally administered IMI in corn oil at a concentration of 1 mg/mL for kg BW/day, whereas their respective controls were orally administered corn oil only (1 mL/kg of body weight) daily for 65 days...
November 30, 2016: Environmental Pollution
https://www.readbyqxmd.com/read/27909620/is-normal-saline-the-best-irrigation-fluid-to-be-used-during-percutaneous-nephrolithotomy-in-renal-failure-patient-a-prospective-randomized-controlled-trial
#2
Bimalesh Purkait, Manoj Kumar, Ankur Bansal, Ashok Kumar Sokhal, Satya Narayan Sankhwar, Kawaljit Singh
OBJECTIVE: Endoscopic procedures like percutaneous nephrolithotomy (PCNL) needs continuous irrigation for better vision and to wash away stone fragments and blood clots. Systemic absorption of irrigation fluids may lead to fluid overload and electrolyte disequilibrium. Renal failure patients are more prone to these electrolyte disturbances. We have evaluated the outcomes of normal saline as irrigation solution to be used in renal failure patient in comparison to distilled water. METHODS: Seventy-six patients with renal calculi were enrolled in this study between September, 2014, and December, 2015...
December 2016: Turkish Journal of Urology
https://www.readbyqxmd.com/read/27876958/effect-of-haemoproteus-columbae-infection-on-the-hemogram-of-the-pigeons-columba-livia-domestica
#3
Amir Dehghani Samani, Khodadad Pirali Kheirabadi, Abdonnaser Mohebbi
It has been reported that parasites affect the health and productivity of birds, initiate excessive preening which interrupts feeding, as the birds spend much time preening rather than being involved in other essential life activities. Haemoproteuscolumbae occurs in pigeons widely in tropical and subtropical regions. The present investigation was concentrated on the effect of H. columbae infection on the hemogram and changes in the number of white blood cells in infected pigeons. Blood samples taked from 100 pigeons in Shahrekord...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27865186/relationship-between-neutrophil-lymphocyte-ratio-and-severity-of-lower-extremity-peripheral-artery-disease
#4
Jacob Teperman, David Carruthers, Yu Guo, Mallory P Barnett, Adam A Harris, Steven P Sedlis, Michael Pillinger, Anvar Babaev, Cezar Staniloae, Michael Attubato, Binita Shah
BACKGROUND: The aim of this study was to determine the association between neutrophil-lymphocyte ratio (NLR) and severity of lower extremity peripheral artery disease (PAD). METHODS: A retrospective chart review identified 928 patients referred for peripheral angiography. NLR was assessed from routine pre-procedural hemograms with automated differentials and available in 733 patients. Outcomes of interest were extent of disease on peripheral angiography and target vessel revascularization...
November 14, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27784356/-clinicopathologic-characteristics-and-outcome-of-isolated-ovarian-relapse-in-adolescent-with-acute-lymphoblastic-leukemia
#5
Ya-Ping Yu, Ping Song, Jian-Gang Mei, Zhi-Ming An, Xiao-Gang Zhou, Feng Li, Li-Ping Wang, Yu-Mei Tang, Yong-Ping Zhai
OBJECTIVE: To investigate the clinicopathologic characteristics,diagnosis and treatment of isolated ovarian relapse of acute lymphoblastic leukemia(ALL). METHODS: A 16-year-old girl presented with complaints of bone and joint pain. The peripheral blood and bone marrow(BM) smears showed 32% and 72% blasts, respectively, which were myeloperoxidase-negative. The blasts were positive for HLA-DR, TdT, CD10, CD19, CD22 and cCD79a and negative for CD34, CD5, CD7, CD13, CD33, CD56 and MPO detected by flow cytometry...
October 2016: Zhongguo Shi Yan Xue Ye Xue za Zhi
https://www.readbyqxmd.com/read/27784351/-establishment-of-mouse-model-with-humanized-chronic-myeloid-leukemia
#6
Yu-Jie Xu, Wen-Hua Jia, Cang-Chun Liu, Wan-Ru Chen, De-Peng Li, Yi-Hong Huang
OBJECTIVE: To establish a BALB/c nude mouse model with the huamanized chronic myeloid leukemia (CML) for the study of human CML. METHODS: The BALB/c nude mice aged 4 weeks pretreated by splenectomy, the cyclophosphamide intraperitoneal injection and sublethal irradiation (SLI) were transplanted intravenously with bone marrow mononuclear cells from CML patients. The SLI-pretreated nude mice were divided into 2 groups: group A, in which the nude mice were injected with 0...
October 2016: Zhongguo Shi Yan Xue Ye Xue za Zhi
https://www.readbyqxmd.com/read/27727360/association-between-interleukin-6-174-g-c-promoter-gene-polymorphism-and-runners-responses-to-the-dietary-ingestion-of-antioxidant-supplementation-based-on-pequi-caryocar-brasiliense-camb-oil-a-before-after-study
#7
Ana Luisa Miranda-Vilela, Ieler Ferreira Ribeiro, Cesar Koppe Grisolia
Exercise is a double-edged sword: when practiced in moderation, it increases the expression of antioxidant enzymes, but when practiced strenuously it causes oxidative stress and cell damage. In this context, polymorphisms in the interleukin (IL)-6 gene should be investigated better because they can influence performance, at least in exercise that generates oxidative stress and leads to muscular injuries with consequent inflammation. In this work, we investigated the influence of IL-6 -174 G/C polymorphism on tissue damage and inflammation markers, lipid peroxidation, hemogram and lipid profile of runners before and after ingestion of 400 mg of pequi oil in capsules supplied daily for 14 consecutive days...
October 2016: Genetics and Molecular Biology
https://www.readbyqxmd.com/read/27717800/effect-of-iron-deficiency-anemia-and-iron-supplementation-on-hba1c-levels-implications-for-diagnosis-of-prediabetes-and-diabetes-mellitus-in-asian-indians
#8
S V Madhu, Abhishek Raj, Stuti Gupta, S Giri, Usha Rusia
BACKGROUND: We investigated the effect of iron deficiency anemia (IDA) on levels of glycated hemoglobin (HbA1c) and to compare its levels before and after iron supplementations. METHODS: Age and sex matched subjects were enrolled and clustered in 2 groups: IDA (n=62) and healthy controls (HC; n=60). HbA1c levels were estimated by HPLC. Hemogram were estimated by hematology analyser. Serum ferritin (ELISA) and other parameters of iron profile were measured by standard guidelines of ICSH...
October 5, 2016: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/27688423/evaluation-of-periodontal-parameters-in-patients-with-early-stage-chronic-lymphocytic-leukemia
#9
Nives Rinčić, Darko Božić, Goran Rinčić, Petar Gaćina, Darije Plančak
OBJECTIVE: To assess periodontal conditions in patients with early stage CLL and to compare it with the periodontal status of age matched healthy controls and to analyze the relationship between periodontal and hematological parameters in CLL patients. MATERIALS AND METHODS: 60 subjects were examined: 30 patients with CLL Rai 0 (test group) and 30 age-matching healthy individuals (control group). The exclusion criteria were: presence of other systemic disease or condition (e...
March 2016: Acta Stomatologica Croatica
https://www.readbyqxmd.com/read/27678153/correlations-of-maternal-neutrophil-to-lymphocyte-ratio-nlr-and-platelet-to-lymphocyte-ratio-plr-with-birth-weight
#10
Nilufer Akgun, Muberra Namlı Kalem, Ebru Yuce, Ziya Kalem, Hatice Aktas
OBJECTIVE: The aim of this study is to investigate the possible correlation of hemogram parameters including NLR and PLR with birth weight and gestational week. MATERIALS AND METHODS: This prospective study has been conducted with 783 patients. The maternal age, parity, gestational age, type of delivery, values of CBC variables, and the weight of newborn were recorded. We analyzed the statistical differences between the NLR, PLR, HGB, PDW, RDW, MPV, platelet, neutrophil, lymphocyte, and WBC in terms of the birth weight...
September 27, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27652358/the-role-of-platelet-count-mean-platelet-volume-and-the-mean-platelet-volume-platelet-count-ratio-in-predicting-postoperative-vomiting-in-children-after-deep-sedation
#11
Dilek G Canpolat, Fatma Dogruel, Zeynep B Gönen, Canay Yılmaz, Gokmen Zararsız, Alper Alkan
OBJECTIVES: To determine the role of hemogram parameters such as platelet count (PLT), mean platelet volume (MPV), and the MPV/PLT ratio in predicting the risk of postoperative vomiting (POV) in children after tooth extraction under deep sedation. METHODS: A total of 100 American Society of Anesthesiology Classification I and II pediatric patients who underwent tooth extraction procedures under a standard anesthetic method were included in the study between 2012 and 2014...
October 2016: Saudi Medical Journal
https://www.readbyqxmd.com/read/27632389/deregulation-of-vital-mitotic-kinase-phosphatase-signaling-in-hematopoietic-stem-progenitor-compartment-leads-to-cellular-catastrophe-in-experimental-aplastic-anemia
#12
Ritam Chatterjee, Sukalpa Chattopadhyay, Sujata Law
Aplastic anemia, the paradigm of bone marrow failure, is characterized by pancytopenic peripheral blood and hypoplastic bone marrow. Among various etiologies, inappropriate use of DNA alkylating drugs like cyclophosphamide and busulfan often causes the manifestation of the dreadful disease. Cell cycle impairment in marrow hematopoietic stem/progenitor compartment together with cellular apoptosis has been recognized as culpable factors behind aplastic pathophysiologies. However, the intricate molecular mechanisms remain unrevealed till date...
November 2016: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/27615666/association-of-neutrophil-lymphocyte-ratio-with-metabolic-syndrome-and-its-components-in-asian-indians-cures-143
#13
Jayagopi Surendar, Karunakaran Indulekha, Viswanathan Mohan, Rajendra Pradeepa
BACKGROUND: Metabolic syndrome (MS) is the state of chronic low grade inflammation. This study looks at the relationship of neutrophil-lymphocyte ratio (NLR) in subjects with and without MS in Asian Indians. METHODS: Study subjects (n=754) were recruited from the Chennai Urban Rural Epidemiology Study. MS was defined using the National Cholesterol Education Program-Adult Treatment Panel (NCEP-ATP) III criteria modified for waist according to World Health Organization Asia Pacific guidelines...
November 2016: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/27614228/myh9-related-disorder-a-probable-may-hegglin-anomaly-case-series-a-tertiary-care-experience
#14
Vandana Kamath, Kiruthiga Kala Gnanasekaran, Joy Mammen
OBJECTIVE/BACKGROUND: May-Hegglin anomaly (MHA) is a rare familial bleeding disorder characterized by a triad of thrombocytopenia, giant platelets, and Döhle-like inclusion bodies within the leukocytes. The clinical spectrum as well as the pathophysiology of this entity is not well defined. The objective of this work is to present a series of three cases of MHA diagnosed in our hospital, where the patients presented with variable bleeding manifestations, thrombocytopenia, and giant platelets...
December 2016: Hematology/oncology and Stem Cell Therapy
https://www.readbyqxmd.com/read/27600691/ameliorative-effect-of-black-grape-juice-on-systemic-alterations-and-mandibular-osteoradionecrosis-induced-by-whole-brain-irradiation-in-rats
#15
Robson B Freitas, Paquita González, Nara Maria B Martins, Edson R Andrade, María Jesús Cesteros Morante, Iban Conles Picos, Serafín Costilla García, Liliane F Bauermann, Juan Pablo Barrio
PURPOSE: Whole brain irradiation (WBI) causes a variety of secondary side-effects including anorexia and bone necrosis. We evaluated the radiomodifying effect of black grape juice (BGJ) on WBI alterations in rats measuring food and water intake, body weight, hemogram, and morphological and histological mandibular parameters. MATERIALS AND METHODS: Forty male rats (200-250 g) were exposed to eight sessions of cranial X-ray irradiation. The total dose absorbed was 32 Gy delivered over 2 weeks...
October 7, 2016: International Journal of Radiation Biology
https://www.readbyqxmd.com/read/27598581/clinical-characteristics-of-cerebrovascular-pathology-with-patients-suffering-from-ph-negative-myeloproliferative-disease
#16
Marine M Tanashyan, Polina I Kuznetsova, Alla A Shabalina, Anton A Raskurazhev, Olga V Lagoda, Irina N Subortseva, Anait L Melikyan
BACKGROUND: Disturbances of microcirculation play a significant role in the development and progression of both acute and chronic cerebrovascular diseases (CVD) and may be associated with different hemogram abnormalities. One of the reasons of the prothrombogenic state of the endothelium is the increase in the number of blood corpuscles leading to (non-Ph) myeloproliferative disorders (MPD) including essential thrombocythemia (ET), polycythemia vera (PV), and primary myelofibrosis (PM)...
September 7, 2016: Cerebrovascular Diseases Extra
https://www.readbyqxmd.com/read/27578978/mean-platelet-volume-in-bipolar-disorder-the-search-for-an-ideal-biomarker
#17
Derya Guliz Mert, Hatice Terzi
BACKGROUND: The pathophysiology of bipolar disorder (BD) remains a mystery. In this context, interest in the role of the immune and inflammatory systems in BD has been increasing. We aimed to compare the routine hemogram values of BD patients with those of the participants in the healthy control group, to assess the inflammation levels of the two groups. Mean platelet volume (MPV) can be obtained as routine hemogram parameters and may aid in the detection of systemic inflammation. SUBJECTS AND METHODS: This study was conducted with BD (manic episode) inpatients (n=132) and healthy controls (n=135)...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27574431/relationship-between-neutrophil-lymphocyte-ratio-with-oxidative-stress-and-psychopathology-in-patients-with-schizophrenia
#18
Burak Kulaksizoglu, Sibel Kulaksizoglu
INTRODUCTION: The aim of our study was to evaluate the relationship between neutrophil/lymphocyte ratio (NLR) and total antioxidant status (TAS), total oxidative status (TOS), oxidative stress index (OSI), paraoxonase, and total thiol (T.thl) in schizophrenic patients compared to healthy control group and investigate the relationship between these parameters and psychopathological symptoms. METHODS: The study population consisted of 61 healthy control subjects and 64 volunteer patients monitored in the outpatient clinics of psychiatry of Antalya Education and Research Hospital...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27561397/assessment-and-comparison-of-pregnancy-outcome-among-anaemic-and-non-anaemic-primigravida-mothers
#19
Rohini Sehgal, Alka Kriplani, Perumal Vanamail, Leema Maiti, Shobha Kandpal, Neeta Kumar
BACKGROUND: Primigravidas (PGs) are high-risk women and anemia in pregnancy is one of the commonest causes of maternal morbidity and mortality. OBJECTIVES: The study was conducted to assess impact of anemia on course and outcome of pregnancy in anemic (Hemoglobin 8-10.9 gm%) and nonanemic PGs. METHODS: This prospective longitudinal study was conducted in All India Institute of Medical Sciences, New Delhi. PGs 20-30 years age, gestation age 16-18 weeks, hemoglobin >8 gm%, live singleton pregnancy, and no other medical illness were recruited after informed consent...
July 2016: Indian Journal of Public Health
https://www.readbyqxmd.com/read/27541023/agranulocytosis-under-biotherapy-in-rheumatoid-arthritis-three-cases-hypothesis-of-parvovirus-b19-involvement-in-agranulocytosis-observed-under-tocilizumab-and-rituximab-for-the-treatment-of-rheumatoid-arthritis
#20
REVIEW
C Giraud, Z Tatar, M Soubrier
Leukopenia is a considerably common complication of tocilizumab [TCZ] and rituximab [RTX] therapy. RTX-induced leukopenia typically exhibits delayed onset. While agranulocytosis has been reported linked to RTX treatment of lymphoma, this complication rarely occurs in rheumatoid arthritis (RA) treatment and, to our knowledge, has never been reported in association with TCZ therapy. We herein report four agranulocytosis cases in three patients, with the first two cases suspected to be secondary to human parvovirus B19 (PVB19) infection...
October 2016: Clinical Rheumatology
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