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https://www.readbyqxmd.com/read/29650038/a-lifelong-study-of-a-pack-rhodesian-ridgeback-dogs-reveals-subclinical-and-clinical-tick-borne-anaplasma-phagocytophilum-infections-with-possible-reinfection-or-persistence
#1
Emil Hovius, Arnout de Bruin, Leo Schouls, Joppe Hovius, Niels Dekker, Hein Sprong
BACKGROUND: Various tick-borne infections often occur without specific clinical signs and are therefore notoriously hard to diagnose separately in veterinary practice. Longitudinal studies over multiple tick seasons performing clinical, serological and molecular investigations in parallel, may elucidate the relationship between infection and disease. In this regard, six related Rhodesian Ridgeback dogs living as a pack became subject of lifetime studies due to ongoing tick infestations and recurring clinical problems...
April 12, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29628691/prospective-study-of-immunomodulation-in-osteoarticular-tuberculosis-non-responsive-to-anti-tubercular-therapy
#2
Saurabh, B P Sharma, Amit Kumar, Saubhik Das, Shambhu Prasad
Background: Tuberculosis is one of the common disease of Indian subcontinent. India has the highest TB burden, accounting for one fifth of the global incidence. Previous studies have shown positive response of immunomodulation in patients of ostearticular tuberculosis We did this prospective study to assess the role of immunomodulation in the cases of osteoarticular tuberculosis who were not responding to anti tubercular therapy. Materials and method: This study was conducted in our institute...
March 2018: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/29622875/study-of-complete-haemogram-and-iron-profile-from-cord-blood-of-newborn-with-respect-to-primigravida-multigravida-and-apgar-score
#3
Madhumita Mondal, Swapan Kumar Sinha, Moumita Sengupta, Debdas Bose, Sudip Saha, Utpal Chaudhuri
Study of different parameters of cord blood usually reflects neonatal health status. One of the widely used system for assessing neonatal health is APGAR score. It is assed at 1 and 5 min from baby's birth. Immediate medical care may improve 5 min score of neonate who showed poor score at 1 min. The main objective of this study is to establish whether any correlation exists between complete hemogram and iron profile with APGAR score and gravid of mother. Cord blood was collected from 96 new born, delivered vaginally, mothers having no chronic medical disease...
April 2018: Indian Journal of Hematology & Blood Transfusion
https://www.readbyqxmd.com/read/29616647/epidemiology-of-malignant-hemopathies-recorded-in-hospitals-in-cameroon
#4
P T Moueleu Ngalagou, E Ngouadjeu Dongho Tsakeu, F Ngo Sack, E C Eboumbou Moukoko, Y Konn Jolly, H Luma
Data about malignant blood diseases are sparse in Cameroon. Their epidemiology was studied in patients at the General Hospital of Douala (GHD) and the Yaoundé Central Hospital (CHY) from 2004 through 2014. The variables we studied were social and demographic (age, sex, occupation, marital status), clinical (reasons for consultation, clinical signs, year of diagnosis), and biological (blood count, myelogram and blood smear, immunophenotyping, biopsy, and cytogenetics). In all, 4409 files were reviewed and 454 cases identified, documented and confirmed (248 in GHD and 206 in CHY)...
February 1, 2018: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/29578147/comparison-of-the-efficacy-of-strontium-89-chloride-in-treating-bone-metastasis-of-lung-breast-and-prostate-cancers
#5
Xiaojuan Ye, Da Sun, Cen Lou
Objective: The aim of this study was to comparatively evaluate the efficacy of strontium-89 chloride (89 SrCl2 ) in treating bone metastasis-associated pain in patients with lung, breast, or prostate cancer. Materials and Methods: The 126 patients with lung cancer included 88, 16, 15, 4, and 3 patients with adenocarcinoma, squamous cell carcinoma, nonsmall cell carcinoma, mixed carcinoma, and small cell carcinoma, respectively, and the control group consisted of patients with breast (71 patients) or prostate cancer (49 patients) who underwent89 SrCl2 treatment during the same period...
2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29562891/correlation-between-maternal-and-umbilical-cord-blood-in-pregnant-women-of-pokhara-valley-a-cross-sectional-study
#6
Sameer Timilsina, Sirisa Karki, Aajeevan Gautam, Pujan Bhusal, Gita Paudel, Deepak Sharma
BACKGROUND: Complete blood count is one of the routinely advised blood investigation during pregnancy. It is also utilized as a diagnostic tool for neonatal anemia, sepsis and determining hemostatic status of the newborn. The present study aims at estimating the complete blood count of maternal and umbilical cord blood at the time of delivery and to establish its correlation. METHOD: This cross sectional study included 114 mothers and their healthy neonates born through normal vaginal delivery...
March 21, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29559378/acute-alterations-in-the-hematological-and-hemorheological-profile-induced-by-resistance-training-and-possible-implication-for-microvascular-functionality
#7
Daniel A Bizjak, Daniel Jacko, Philipp Zimmer, Sebastian Gehlert, Wilhelm Bloch, Marijke Grau
Depending on the exercise variables and training design, resistance exercise can be applied to gain muscle mass, prevent diseases like osteoporosis and sarcopenia or generally increase strength capacity. But the influence on blood flow parameters and possible consequences in health and disease are less understood. To examine the possible impact of resistance exercise of different duration on hemorheology, oxidative stress and microvascular function, participants (n = 6) performed lower-limb resistance exercise of the quadriceps femoris...
March 17, 2018: Microvascular Research
https://www.readbyqxmd.com/read/29555411/clinical-features-of-acute-human-immunodeficiency-virus-infection-in-taiwan-a-multicenter-study
#8
Te-Yu Lin, Chia-Jui Yang, Chung-Eng Liu, Hung-Jen Tang, Tun-Chieh Chen, Guan-Jhou Chen, Tung-Che Hung, Kuan-Yin Lin, Chien-Yu Cheng, Yi-Chien Lee, Shih-Ping Lin, Mao-Song Tsai, Yu-Lin Lee, Shu-Hsing Cheng, Chien-Ching Hung, Ning-Chi Wang
BACKGROUND/PURPOSE: Acute HIV infection is characterized by a high concentration of HIV RNA in the plasma and rapid depletion of the CD4 cell count. This multicenter, retrospective observational study aimed to characterize the manifestations of acuteHIV infection in Taiwan. METHODS: Between 1 January 2012 and 31 December 2016, all patients aged 20 years or greater who presented with acute HIV infection were included. Demographic and clinical characteristics of the patients at diagnosis were collected...
March 2, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/29548288/relationship-between-high-density-lipoprotein-cholesterol-and-the-red-cell-distribution-width-in-patients-with-coronary-artery-disease
#9
Eyup Avci, Tuncay Kiris, Abdullah Orhan Demirtas, Hasan Kadi
BACKGROUND: The red cell distribution width (RDW) is a numerical measurement of variability in the size of red blood cells. Many studies have shown that high-density lipoprotein cholesterol (HDL-C), has an anti-inflammatory effect. The aim of this study was to investigate the relationship between the serum HDL-C level and RDW in patients with coronary artery disease (CAD). METHODS: Patients who underwent coronary angiography were reviewed. Patients who had moderate or severe heart failure, moderate or severe renal failure, significant systemic disease, anemia, a blood transfusion within the last 3 months, or a hematologic disease, as well as those who were taking lipid-lowering medication, were excluded from the study...
March 16, 2018: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29546926/-perinatal-dengue-a-case-report
#10
Ramiro Manzano Núñez, James Alejandro Zapata, Herney A García-Perdomo, Diego A Gomez, Mónica A Solís Velasco
INTRODUCTION: Few reports are available about perinatal dengue, with controversial results in regards the risk of perinatal outcome. OBJECTIVE: To report a case of perinatal dengue as a differential diagno sis with neonatal sepsis, which must be considered in endemic areas. CLINICAL CASE: Male newborn of a 23 year-old female, who presented a Non-Structural Protein 1 (NS1) antigen positive to dengue at 36 weeks of gestation and negative anti-dengue antibodies...
December 2017: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/29534635/reference-intervals-for-hemoglobin-and-hematocrit-in-a-low-risk-pregnancy-cohort-implications-of-racial-differences
#11
Giuseppe Chiossi, Stefano Palomba, Maged M Costantine, Angela I Falbo, Hassan M Harirah, George R Saade, Giovanni B La Sala
OBJECTIVE: As anemia in pregnancy is associated with adverse perinatal outcomes, we sought to define the mean and the fifth percentile of Hb and Ht using a contemporary multiethnic large cohort of low risk pregnancies, and assess potential racial differences. METHODS: We conducted a retrospective cohort study on women who delivered between 1 January 2008 and 31 December 2013 in Reggio Emilia County, Italy. Linear mixed effects models were used to describe changes in mean Hb and Ht, while quantile regression with matrix-design bootstrap defined changes in the fifth percentile of Hb and Ht, controlling for race, maternal age, smoking, and pregnancy number...
March 13, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29523134/effects-of-herbal-nutraceuticals-and-or-zinc-against-haemonchus-contortus-in-lambs-experimentally-infected
#12
Zora Váradyová, Dominika Mravčáková, Michal Babják, Magdalena Bryszak, Ľubomíra Grešáková, Klaudia Čobanová, Svetlana Kišidayová, Iveta Plachá, Alžbeta Königová, Adam Cieslak, Sylwester Slusarczyk, Lukasz Pecio, Mariusz Kowalczyk, Marián Várady
BACKGROUND: The gastrointestinal parasitic nematode Haemonchus contortus is a pathogenic organism resistant to several anthelmintics. This study assessed the efficacy of a medicinal herbal mixture (Herbmix) and organic zinc, as an essential trace element for the proper functioning of both unspecific and specific immune defensive mechanisms, against experimental infections with H. contortus in lambs. All lambs were infected orally with approximately 5000 third-stage larvae of a strain of H...
March 9, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/29496418/a-short-18-items-food-frequency-questionnaire-biochemically-validated-to-estimate-zinc-status-in-humans
#13
Sarah Trame, Inga Wessels, Hajo Haase, Lothar Rink
Inadequate dietary zinc intake is wide-spread in the world's population. Despite the clinical significance of zinc deficiency there is no established method or biomarker to reliably evaluate the zinc status. The aim of our study was to develop a biochemically validated questionnaire as a clinically useful tool that can predict the risk of an individual being zinc deficient. From 71 subjects aged 18-55 years blood and urine samples were collected. Zinc concentrations in serum and urine were determined by atomic absorption spectrometry...
February 21, 2018: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/29472768/effect-of-zhen-qi-fu-zheng-granules-on-the-bone-marrow-depression-model-induced-by-zidorf
#14
Mingsan Miao, Lihua Cao, Ming Bai, Gangling Chen
Zidorf is a commonly used drug for the treatment of AIDS, the most common side effects of AZT was bone marrow depression. Therefore, we investigated the effects of Zhen Qi Fu Zheng (AQFZ) granules on the model of bone marrow depression induced by AZT. We showed that the high, medium and low doses of AQFZ granules could increase the number of WBC in the mice model induced by AZT, and the difference was significant ( P  < 0.01) compared with the model group. Each dose of AQFZ granules can increase the thymus cortex thickness, the number of thymus lymphocytes, spleen nodule size, the number of lymphocytes in the spleen ( P  < 0...
February 2018: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/29434729/a-composite-mouse-model-of-aplastic-anemia-complicated-with-iron-overload
#15
Dijiong Wu, Xiaowen Wen, Wenbin Liu, Linlong Xu, Baodong Ye, Yuhong Zhou
Iron overload is commonly encountered during the course of aplastic anemia (AA), but no composite animal model has been developed yet, which hinders drug research. In the present study, the optimal dosage and duration of intraperitoneal iron dextran injection for the development of an iron overload model in mice were explored. A composite model of AA was successfully established on the principle of immune-mediated bone marrow failure. Liver volume, peripheral hemogram, bone marrow pathology, serum iron, serum ferritin, pathological iron deposition in multiple organs (liver, bone marrow, spleen), liver hepcidin, and bone morphogenetic protein 6 (BMP6), SMAD family member 4 (SMAD4) and transferrin receptor 2 (TfR2) mRNA expression levels were compared among the normal control, AA, iron overload and composite model groups to validate the composite model, and explore the pathogenesis and features of iron overload in this model...
February 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29411723/diagnostic-role-of-neutrophil-lymphocyte-ratio-in-oral-cavity-cancers
#16
M D Zl, R Karamert, H Tutar, M Şahin, A Türkcan, M Yılmaz
AIM: In this study, we aimed to evaluate the diagnostic role of neutrophil-lymphocyte ratio (NLR) and other hemogram parameters in differentiating nonmalignant oral cavity lesions from oral cavity cancers. METHODS: Ninety-five patients who were performed oral cavity biopsy between the years 2013 and 2015 were retrospectively reviewed. The control group comprised consecutive 70 patients who underwent septoplasty/septorhinoplasty procedures. Inclusion criteria were to be available with common blood count (CBC) just prior to procedure...
January 2018: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29408596/clinical-and-immunological-profiles-of-anaemia-in-children-and-adolescents-with-plasmodium-vivax-malaria-in-the-par%C3%A3-state-brazilian-amazon
#17
Ana Maria Revoredo da Silva Ventura, Andrea Aparecida Moraes Fernandes, Graziela Maria Zanini, Lilian Rose Pratt-Riccio, Carina Guilhon Sequeira, Carlos Rodrigo Souza do Monte, Arnaldo Jorge Martins Filho, Ricardo Luiz Dantas Machado, Rosana Maria Feio Libonati, José Maria de Souza, Cláudio Tadeu Daniel-Ribeiro
Children and adolescents are at great risk for developing iron deficiency anaemia worldwide. In the tropical areas, malaria and intestinal parasites may also play an important role in anaemia pathogenesis. This study aimed at evaluating clinical and immunological aspects of anaemia in children and adolescents with Plasmodium vivax malaria, in the Pará State, Brazil. A longitudinal study was performed in two Reference Centres for malaria diagnosis in the Brazilian Amazon in children and adolescents with malaria (n = 81), as compared to a control group (n = 40)...
February 1, 2018: Acta Tropica
https://www.readbyqxmd.com/read/29404160/spontaneous-splenic-rupture-in-the-early-postoperative-period-to-after-lobectomy
#18
Ayşe Gül Ergönül, Tevfik İlker Akçam, Ali Özdil, Ufuk Çağırıcı
Spontaneous splenic rupture is a quite rare entity that may develop secondary to some special situations (lymphoma, post-abdominal surgey etc). In the literature, the case of a patient has been reported following thoracic surgery. In a patient who had undergone right upper lobectomy for pulmonary carcinoma, signs of acute abdomen and low levels in the hemogram were detected on the fifth postoperative day; therefore, the patient underwent further investigations. A radiological evaluation revealed splenic rupture, and the patient was operated on...
April 2017: Turkish Thoracic Journal
https://www.readbyqxmd.com/read/29403202/thrombocytosis-in-children-clinico-hematological-profile-from-a-single-centre-in-eastern-india
#19
Rachita Sarangi, Sarita Pradhan, Avantika Dhanawat, Rashmi Patanayak, Gautam Benia
BACKGROUND AND OBJECTIVE: Thrombocytosis is not an uncommon finding in hemograms of children with an incidence of 6%-15% among hospitalized children. This study aims to determine the etiology of thrombocytosis and analyze various platelet parameters in children attending our hospital. MATERIALS AND METHODS: A prospective observational study was carried out in a tertiary care center in Odisha, in eastern part of India, for 6 months from July 2016 to December 2016...
January 2018: Journal of Laboratory Physicians
https://www.readbyqxmd.com/read/29401268/voluntary-intake-and-digestibility-by-sheep-of-alfalfa-ensiled-at-different-moisture-concentrations-following-fertilization-with-dairy-slurry
#20
J K Clark, K P Coffey, W K Coblentz, B C Shanks, J D Caldwell, R E Muck, D Philipp, M A Borchardt, R T Rhein, W E Jokela, E A Backes, M G Bertram, W B Smith
Dairy slurry is used commonly as an animal-sourced fertilizer in agronomic production. However, residual effects of slurry application on intake and digestibility of alfalfa (Medicago sativa L.) silage from subsequent harvests are not well known. The objective of this study was to determine if moisture concentration of alfalfa silage and timing of dairy slurry application relative to subsequent harvest affected intake and digestibility by sheep. Katahdin crossbred ewes (n = 18; 48 ± 5.3 kg) in mid-gestation were stratified by BW and allocated randomly in each of 2 periods to 1 of 6 treatments arranged in a 2 × 3 factorial arrangement...
February 1, 2018: Journal of Animal Science
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