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https://www.readbyqxmd.com/read/29221152/distal-embolization-versus-combined-embolization-techniques-for-blunt-splenic-injuries-comparison-of-the-efficacy-and-complications
#1
Yon-Cheong Wong, Cheng-Hsien Wu, Li-Jen Wang, Huan-Wu Chen, Kuo-Ching Yuan, Being-Chuan Lin, Yu-Pao Hsu, Shih-Ching Kang
Comparable failure rates of distal or proximal transcatheter arterial embolization (TAE) techniques for blunt splenic injuries have been reported. This study is to investigate the efficacy and complication of combining both TAE techniques. We included 26 patients of blunt splenic injuries for TAE therapy and randomized them into distal TAE and combined TAE groups. A prospective study was performed to compare their demographics, clinical parameters, hemograms, post-TAE splenic infarct volumes, splenic abscess and pancreatitis between the two groups...
November 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29208882/thrombocytopenia-in-late-onset-neonatal-sepsis-and-its-relationship-with-specific-organism-in-a-tertiary-care-hospital
#2
F Ahmed, A Y Raj, L N Begum
Late onset neonatal sepsis (LONS) is a common complication in the Neonatal Intensive Care Unit (NICU) especially in premature infants, in whom the clinical presentation can be subtle and nonspecific. Thrombocytopenia is an important complication of sepsis. The objective of the present study was to identify the organism-speci?c platelet response in neonate with culture proven LONS. In this retrospective study all the infants with blood culture positive LONS in the neonatal intensive care unit (NICU) at Square Hospitals Ltd...
October 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29201765/association-of-severity-of-helicobacter-pylori-infection-with-peripheral-blood-neutrophil-to-lymphocyte-ratio-and-mean-platelet-volume
#3
Mustafa Guclu, A Faruq Agan
Aim: To determine the correlation of Helicobacter pylori infection with peripheral blood neutrophil/lymphocyte ratio (NLR) and mean platelet volume (MPV). Materials and methods: The NLR, MPV, platelets, leukocytes, neutrophils, and lymphocytes were calculated and the differences between groups were investigated. Results: A total of 199 patients were included in the study. Neutrophil/lymphocyte ratio was statistically lower in H. pylori-positive patients than in H...
January 2017: Euroasian Journal of Hepato-Gastroenterology
https://www.readbyqxmd.com/read/29179457/traditional-chinese-medicine-danggui-buxue-tang-inhibits-colorectal-cancer-growth-through-induction-of-autophagic-cell-death
#4
Shun-Ting Chen, Tzung-Yan Lee, Tung-Hu Tsai, Yu-Chuen Huang, Yin-Cheng Lin, Chin-Ping Lin, Hui-Ru Shieh, Ming-Ling Hsu, Chih-Wen Chi, Ming-Cheng Lee, Hen-Hong Chang, Yu-Jen Chen
Purpose: The induction of autophagic cell death is an important process in the development of anticancer therapeutics. We aimed to evaluate the activity of the ancient Chinese decoction Danggui Buxue Tang (DBT) against colorectal cancer (CRC) and the associated autophagy-related mechanism. Materials and methods: CT26 CRC cells were implanted into syngeneic BALB/c mice for the tumor growth assay. DBT extracts and DBT-PD (polysaccharide-depleted) fractions were orally administered...
October 24, 2017: Oncotarget
https://www.readbyqxmd.com/read/29146407/-hemogram-profile-and-interest-of-pre-donation-hemoglobin-measurement-in-blood-donors-in-the-northwest-region-of-morocco
#5
S Bakrim, A Ouarour, K Jaidann, M Benajiba, A Masrar
BACKGROUND: Blood donation in Morocco and more particularly in the northwest region is carried out without prior determination of the pre-donation hemoglobin. In addition, we note the lack of scientific research that reports data on the red blood cells, leukocytes and platelet lines in donated blood at the regional or even national level. AIMS: To study hemogram profile in blood donors taken from the Northwest region of Morocco in order to provide decision makers of the National Center of Blood Transfusion and Hematology with valid scientific arguments to complete the criteria to donate whole blood, by the hemogram...
November 13, 2017: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
https://www.readbyqxmd.com/read/29137105/urgent-laparoscopic-ureterolithotomy-for-proximal-ureter-stones-accompanied-with-obstructive-pyelonephritis-is-it-safe-and-effective-without-preoperative-drainage
#6
Huan Yang, Xiao Yu, Ejun Peng, Cong Li, Lei Cui, Xing Zeng, Shen Wang, Chao Wei, Zhihua Wang, Xiaolin Guo, Zhiqiang Chen, Zhangqun Ye, Shaogang Wang, Chenming Zhao
To evaluate the safety and efficacy of retroperitoneal laparoscopic ureterolithotomy (RLU) in the treatment of proximal ureteral stones accompanied with obstructive pyelonephritis without preoperative drainage.We retrospectively reviewed 21 cases of proximal ureteral stones with infected kidney undergoing RLU between July 2013 and September 2016. Stone-induced obstructive infected hydronephrosis was diagnosed using blood and urine tests and imaging modalities. Empirical effective broad spectrum antibiotic therapy was initiated immediately, and then urgent RLU was performed without preoperative drainage...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29128084/-chimerism-analysis-after-hematopoietic-cell-transplantation-guidelines-from-the-francophone-society-of-bone-marrow-transplantation-and-cellular-therapy-sfgm-tc
#7
Valérie Dubois, Mehdi Alizadeh, Jean Henri Bourhis, Pascaline Etancelin, Olivier Farchi, Christophe Ferrand, Laure Goursaud, Isabelle Mollet, Virginie Renac, Pauline Varlet, Ibrahim Yakoub-Agha, Jacques-Olivier Bay
Chimerism analysis is an important step for the patient follow-up after hematopoietic stem cell transplantation. It is used to quantify the donor and the recipient part of a cell population issued from blood or bone marrow sample. In addition to hemogram, this technique is necessary to appreciate the quality of engraftment. The aim of this article is to propose some recommendation about methods, result analysis and therapeutic decision in hematopoietic stem cell transplantation for malignant or non-malignant diseases...
November 8, 2017: Bulletin du Cancer
https://www.readbyqxmd.com/read/29115652/early-laparoscopic-cholecystectomy-following-acute-biliary-pancreatitis-expedites-recovery
#8
Seracettin Eğin, Metin Yeşiltaş, Berk Gökçek, Hakan Tezer, Servet Rüştü Karahan
BACKGROUND: In this retrospective study, we aimed to assess the reliability of early cholecystectomy, risk of recurrent biliary pancreatitis, and their effects on hospital length of stay and morbidity by comparing the results of early and late laparoscopic cholecystectomy in patients with acute biliary pancreatitis. METHODS: A total of 131 patients, who were diagnosed with acute biliary pancreatitis at Okmeydanı Education and Research Hospital in January 2009-December 2012, were included in the study...
November 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/29096305/vnn3-a-potential-novel-biomarker-for-benzene-toxicity-is-involved-in-1-4-benzoquinone-induced-cell-proliferation
#9
Pengling Sun, Xiaoli Guo, Yujiao Chen, Wei Zhang, Huawei Duan, Ai Gao
Benzene is widely employed in the field of production, and its toxicity on biological systems has received increasing attention. Cell proliferation is a major life characteristic of living organisms. KLF15 and NOTCH1 are mature and classical genes in cell proliferation studies, particularly in the area of tumor investigation. The aim of this study was to investigate the effect and mechanism of VNN3 on cell proliferation induced by 1,4-benzoquinone (1,4-BQ), an important metabolite of benzene, and obtain a sensitive biomarker for the hazard screening and health care of benzene exposure...
October 27, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29091474/pilot-study-safety-and-effectiveness-of-simple-ultrasound-guided-high-intensity-focused-ultrasound-ablating-uterine-leiomyoma-with-a-diameter-greater-than-10%C3%A2-cm
#10
Ruijie Hou, Liwei Wang, Shaoping Li, Fengmin Rong, Yuanyuan Wang, Xuena Qin, Shijin Wang
OBJECTIVE: The study aimed to prospectively investigate whether uterine leiomyoma greater than 10 cm in diameter could be treated with simple ultrasound-guided high-intensity focused ultrasound (USgHIFU) in one-time treatment. METHODS: A total of 36 patients with 36 symptomatic uterine leiomyoma greater than 10 cm in diameter who underwent simple USgHIFU treatment alone were analysed. Enhanced MRI was performed before and after HIFU treatment, and all patients had follow-up for 6 months after treatment...
November 21, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29017671/could-red-cell-distribution-width-be-a-marker-of-thyroid-cancer
#11
Gulali Aktas, Mustafa Sit, Ibrahim Karagoz, Edip Erkus, Bahri Ozer, Mehmet Zahid Kocak, Semih Yaman, Fatih Keyif, Rabia Altinordu, Hayri Erkol, Haluk Savli
OBJECTIVE: To study red cell distribution width (RDW) values, a novel inflammatory marker in routine hemogram, of patients with benign or malignant thyroid nodules and to compare with healthy population. STUDY DESIGN: Descriptive study. PLACE AND DURATION OF STUDY: Abant Izzet Baysal University Hospital, Bolu, Turkey, from November 2015 and February 2017. METHODOLOGY: The hemogram values of patients undergone thyroid surgery for thyroid nodule between November 2015 and February 2017 were retrospectively analyzed, and compared to those in healthy subjects...
September 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28993978/anemia-in-patients-with-ulcerative-colitis-in-remission-a-study-from-western-india
#12
Alisha Chaubal, Vikas Pandey, Dhaval Choksi, Prateik Poddar, Meghraj Ingle, Aniruddha Phadke, Prabha Sawant
BACKGROUND: Anemia is common in patients with active ulcerative colitis. We aimed to study the anemia profile in patients with ulcerative colitis in clinical remission. METHODS: Sixty-four patients with ulcerative colitis and with a clinical Mayo score less than 3 for at least 3 months were evaluated for anemia. Initial screening was done by hemogram and only patients with anemia were evaluated further for the cause of anemia. We also screened a control population for anemia...
October 9, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28958967/immune-thrombocytopenia-associated-with-malaria-a-case-report
#13
Mouhcine Miloudi, Mohammed Sbaai, Jamal Fatihi
The association of immune thrombocytopenic with malaria is a rare event. We describ the case of a young soldier who, after returning from Central Africa, presented a fever associated with petechial purpura and gingivorrhagia, hemogram showed deep thrombocytopenia and macrocytic normochrome anemia, thick peripheral blood smears confirmed the diagnosis of Plasmodium falciparum malaria, the patient was treated with quinine, but deep thrombocytopenia and hemorrhagic manifestations persisted, the patient then underwent corticosteroid therapy, with favorable evolution and progressive normalization of platelets...
October 1, 2017: Annales de Biologie Clinique
https://www.readbyqxmd.com/read/28861733/patterns-of-uveitis-in-children-at-the-apex-institute-for-eye-care-in-india-analysis-and-review-of-literature
#14
Brijesh Takkar, Pradeep Venkatesh, Nripen Gaur, Sat Pal Garg, Rajpal Vohra, Supriyo Ghose
AIM: To study patterns of uveitis in Indian children and compare with data sets published earlier in the literature. METHODS: Consecutive patients below 16 years of age presenting to the uvea clinic of a tertiary eye care center were included prospectively through the period of July 2009-August 2013. Children with retinal vasculitis, exogenous endophthalmitis and masquerade syndromes were excluded from analysis. Uveitis was classified as per the nomenclature system adopted by the International Uveitis Study Group...
August 31, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28830584/immune-activation-of-platelets-in-response-to-serial-phlebotomy-in-pigtailed-macaques-macaca-nemestrina
#15
Meghan S Vermillion, Claire E Lyons, Kevin M Najarro, Robert J Adams, Kelly A Metcalf Pate
Serial phlebotomy is a common sampling practice for repeated-measures studies in biomedical research. In NHP, the effect of serial blood collection on RBC parameters has been characterized, but the effects on platelet parameters and other aspects of the hemogram have not been well studied. We sought to characterize the circulating platelet phenotype throughout the course of 7 serial phlebotomies spanning 30 d in pigtailed macaques (Macaca nemestrina). Phlebotomy was performed on 23 animals at days 0, 2, 4, 7, 10, 21, and 30 to quantify the circulating platelet count and markers of both hemostatic and immune platelet activation...
August 1, 2017: Comparative Medicine
https://www.readbyqxmd.com/read/28780099/effect-of-recombinant-bovine-somatotropin-on-leukocyte-mrna-expression-for-genes-related-to-cell-energy-metabolism-cytokine-production-phagocytosis-oxidative-burst-and-adaptive-immunity
#16
P R B Silva, C D Nelson, J P Driver, W W Thatcher, R C Chebel
Objectives of the current experiment were to evaluate the effects of treatment of periparturient dairy cows with recombinant bovine somatotropin (rbST) on mRNA expression in peripheral leukocytes for genes related to the somatotropic axis, cell energy metabolism, and innate and adaptive immune responses. Cows were enrolled in the experiment at 253 ± 3 d of gestation and assigned to an untreated control group (n = 98) or to receive 125 mg of rbST weekly from -21 to 21 d relative to calving (rbST125; n = 98)...
August 2, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28761209/extranodal-non-hodgkin-s-lymphoma-of-the-oral-cavity-a-case-report
#17
Babyamma Raghavan Varun, Nettiyat Oommen Varghese, Trivandrum Thanappan Sivakumar, Anna Palliath Joseph
Lymphomas are solid malignant tumors having a wide spectrum of clinical and pathological features. Non-Hodgkin's lymphoma (NHL) is a subtype of lymphoma with two-thirds of the cases presenting as lymph node enlargement. The remaining one third of NHL cases has been reported in the extranodal sites, including the gastro intestinal tract, Waldeyer's ring, bone, skin, and brain. Intraoral non-Hodgkin's lymphoma is uncommon and may affect either the jaw bones or occur within the soft tissues of the oral cavity...
July 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28752141/neutrophil-gelatinase-associated-lipocalin-reflects-the-severity-of-anemia-without-iron-deficiency-and-secondary-hyperparathyroidism-in-hemodialysis-patients
#18
Irem Pembegul Yigit, Ramazan Ulu, Nevzat Gozel, Hulya Taskapan, Necip Ilhan, Ayhan Dogukan
OBJECTIVE: Secondary hyperparathyroidism (SHPT) and anemia are the primary and most common complications in patients receiving hemodialysis (HD). Neutrophil gelatinase-associated lipocalin (NGAL) is a new marker to assess iron deficiency and manage iron therapy for HD patients. The aim of this study was to determine any association between serum NGAL level and anemia without iron deficiency in patients with SHPT on chronic HD. METHODS: Total of 61 SHPT patients on chronic HD were enrolled in the study and divided into 3 groups: mild SHPT group (n=17), moderate SHPT group (n=21), and severe SHPT group (n=23)...
2017: Northern Clinics of Istanbul
https://www.readbyqxmd.com/read/28749571/l-ornithine-l-aspartate-in-bouts-of-overt-hepatic-encephalopathy
#19
Sandeep Singh Sidhu, Barjesh Chander Sharma, Omesh Goyal, Harsh Kishore, Navpreet Kaur
High quality data on efficacy of L-Ornithine L-Aspartate (LOLA) in cirrhotics with bouts of overt hepatic encephalopathy (OHE) is missing. We aimed to evaluate the efficacy of intravenous LOLA in reversal of bouts of OHE in cirrhotics. In this prospective double-blind randomized placebo controlled trial conducted at two tertiary care institutes in India, 370 cirrhotics with bouts of OHE were screened. After exclusion, 193 (52.16%) patients were randomized to receive either intravenous infusions of LOLA (n=98), 30 grams daily or Placebo (n=95) for 5 days...
July 27, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28748896/sickled-erythrocytes-in-urine-as-a-clue-to-the-diagnosis-of-sickle-cell-trait
#20
Shanu Srivastava, Rashmi Srivastava, K G Ghorpade
Sickled erythrocytes in patients of sickle cell trait with microscopic hematuria have rarely been reported so far. A 30-year-old female underwent delivery of a healthy full-term baby by cesarean section. However, postcesarean, she had pain in abdomen and fever, for which she was advised blood and urine examination. The hemogram suggested mild leukocytosis with neutrophilia and the urine showed red blood cells, some of which were sickled. The patient was advised hemoglobin electrophoresis which suggested sickle cell trait (Hb-AS)...
July 2017: Saudi Journal of Kidney Diseases and Transplantation
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