Bianca Sampaio Dotto Fiuza, Candace Machado de Andrade, Pedro Milet Meirelles, Jorley Santos da Silva, Milca de Jesus Silva, Cinthia Vila Nova Santana, Gabriela Pimentel Pinheiro, Harriet Mpairwe, Philip Cooper, Collin Brooks, Lucy Pembrey, Steven Taylor, Jeroen Douwes, Álvaro A Cruz, Mauricio L Barreto, Neil Pearce, Camila A V Figueiredo
BACKGROUND: Asthma is a complex disease and a severe global public health problem resulting from interactions between genetic background and environmental exposures. It has been suggested that gut microbiota may be related to asthma development; however, such relationships needs further investigation. OBJECTIVE: This study aimed to characterize the gut microbiota as well as the nasal lavage cytokine profile of asthmatic and nonasthmatic individuals. METHODS: Stool and nasal lavage samples were collected from 29 children and adolescents with type 2 asthma and 28 children without asthma in Brazil...
May 2024: J Allergy Clin Immunol Glob